CN112891433A

CN112891433A - Method for preparing Chinese herbal medicine anticancer inhalation

Info

Publication number: CN112891433A
Application number: CN202110076679.2A
Authority: CN
Inventors: 熊俊宇
Original assignee: Hunan Final Technology Co ltd
Current assignee: Hunan Final Technology Co ltd
Priority date: 2021-01-20
Filing date: 2021-01-20
Publication date: 2021-06-04

Abstract

The invention discloses a method for preparing a Chinese herbal medicine anticancer inhalation, which comprises the following steps: s1, selecting materials: the materials are selected from bark and leaves of Taxus chinensis, stems and leaves of Foeniculum vulgare, Pelargonium graveolens, Glycyrrhrizae radix, herba Solani Nigri, herba et Gemma Agrimoniae, herba Hedyotidis Diffusae, herba Lobeliae chinensis, Ginseng radix, herba Corchori oliolithi, Ganoderma and Eucommiae cortex. The invention relates to a method for preparing Chinese herbal medicine anti-cancer smoking articles, which utilizes an extraction process to extract and quickly freeze all anti-cancer components for storage, the explosion beads are broken before smoking, anti-cancer liquid medicine flows into filter tip cotton, when a smoker smokes smoke, the smoke can bring medicine property into the lung through the filter tip cotton, the curative effect of the anti-cancer medicine is fully absorbed by the capillary vessels of the lung, the effect of killing cancer cells is achieved, the function of the smoking article on the mouth is reflected, the smoker can fully smoke the smoking article mouth containing the medicine property in the smoking process, the due effect of the medicine can be fully exerted, and great contribution is made to human health.

Description

Method for preparing Chinese herbal medicine anticancer inhalation

Technical Field

The invention relates to the technical field of cigarette manufacturing, also relates to the technical field of medical traditional Chinese medicine, and in particular relates to application of a Chinese herbal medicine anti-cancer smoking product.

Background

The cigarette is introduced into China from the Ming dynasty for over 400 years, and not only the smoker suffers the harm to himself, but also the second-hand cigarette enables the relatives and friends of the smoker, at present, the cigarette is scientifically developed, the result obtained by scientific detection shows that the second-hand cigarette is harmful to more than 500 kinds of cancer substances, so-called substitutes for the cigarette and health-care products of the cigarette have no scientific basis, the middle ignition point of a common cigarette is 1200 ℃, and all health-care medicines can be cracked, so can the health-care function be achieved? Therefore, in order to solve the pain of smokers who are afflicted by cancer diseases, the invention specially selects 12 anticancer Chinese medicinal materials, extracts anticancer medicinal components in the Chinese medicinal materials, wraps the anticancer medicinal components into blasting beads through a scientific formula, implants the blasting beads into the middle of filter cotton of a cigarette holder, the smokers cut the blasting beads before smoking, liquid medicine flows into the filter cotton of the cigarette holder, smoke of the smokers can bring medicine properties into the lung during smoking, the problem of fission caused by burning tobacco shreds is avoided, the curative effect of the medicine with the medicine properties is achieved, and the smoking addiction of the smokers is also solved.

After years of thought and fine selection, 12 Chinese herbal medicines are selected to have a certain anticancer effect, and the medicinal liquid is atomized into the lung to completely inhibit the growth of cancer cells through a plurality of white rat tests and clinical results.

Ganoderma lucidum: the product is a plant of Polyporaceae, has sweet and mild taste, has effects of invigorating kidney, nourishing heart, and tranquilizing mind, and has effects of inhibiting lung metastasis of mouse subcutaneous transplanted fibrosarcoma, and inhibiting cell toxic activity of P3HP-15CIT26-P3 tumor cell strain, and Ganoderma water extract can inhibit growth of mouse S180 solid tumor.

Sweet in flavor, neutral in nature, entering heart, lung, liver and kidney meridians, and mainly used for treating: has effects in invigorating qi, tranquilizing mind, relieving cough and asthma, and can be used for treating restlessness of heart-mind, insomnia, palpitation, cough and asthma due to lung deficiency, asthenia, short breath, and anorexia.

Eucommia ulmoides: is bark of eucommia ulmoides and eucommia ulmoides of Eucommiaceae, is sweet and warm, has the functions of tonifying liver and kidney and strengthening skeleton and fetus, and has the effect of inhibiting Wacker carcinoma W256 by lupeol contained in eucommia ulmoides; the product has effects in enhancing immunity, regulating cellular immunity, lowering blood pressure, promoting urination, tranquilizing mind, relieving pain, and promoting eye sight.

Herba ephedrae: the product is dry herbaceous stems of Ephedraceae plants, Ephedra E, intermedia chrnktc, A, Mey, or Ephedra equiseti E, equi-setinaBge, green herbaceous stems are picked in autumn and dried in the sun, and the herb is pungent in taste, slightly bitter in taste, warm in nature, enters lung and bladder channels, and has the main treatment effects: inducing sweat and dispelling cold, dispersing lung qi and relieving asthma, inducing diuresis and relieving edema, and can be used for treating wind-cold type common cold, chest distress, asthma, edema due to wind-cold type common cold, bronchial asthma, and lung moistening and cough relieving of herba Ephedrae.

Herba Hedyotidis Diffusae: is the whole herb of spreading hedyotis herb oldde-landdiaffusa (willd) Roxb of the rubiaceae family, has slightly bitter, sweet and cold taste, and is mainly used for treating: it is often used for treating lung cancer, nasopharyngeal carcinoma, laryngeal carcinoma, tongue cancer, liver cancer, esophageal cancer, cervical cancer, ovarian cancer, breast cancer, etc.

Fennel: is dry mature fruit of Umbelliferae plant and Foeniculum vulgare VUI-gare Mill, the plant is picked when the fruit is mature in autumn, the fruit is cut, the impurity is removed, the taste is pungent and warm, the fruit enters liver channel, kidney channel, spleen channel and stomach channel, the main treatment is as follows: dispel cold and alleviate pain, regulate qi and harmonize stomach, and can be used for treating abdominal pain due to hernia of cold, testicular tenesmus, dysmenorrhea, cold pain in lower abdomen, abdominal distention and pain, anorexia and vomiting.

Clove: is a dry bud of Eugenia caryophyllata Thunb of Myrtaceae, commonly called as flos Caryophylli, usually collected from 9 months to 3 months next year when the bud turns from green to red, has pungent and warm taste, and has effects of invigorating spleen, stomach, lung and kidney meridians, and mainly treats: warming middle energizer to check adverse rise of qi, invigorating kidney and tonifying yang, and can be used for treating deficiency-cold of spleen and stomach, singultus emesis, anorexia vomiting and diarrhea, psychroalgia of heart and abdomen, and sexual impotence due to kidney deficiency.

Agrimony: is dry overground part of Agrimonia pilosa-losa Ledeb of Rosaceae, is harvested when stems and leaves are flourishing in summer and autumn, has bitter, astringent and flat taste, and has main functions of heart and liver meridians, and is mainly used for treating: astringe to stop bleeding, stop dysentery, check malaria, remove toxicity, tonify deficiency, and be used for hemoptysis, hematemesis, metrorrhagia and metrostaxis, malaria, bloody dysentery, carbuncle, sore, pruritus vulvae, leukorrhagia, and internal injury due to overstrain.

Ginseng: is dried root and rhizome of Panax ginseng C.A. and Mey belonging to Araliaceae, and wild is named as "mountain Ginseng"; the culturist is called Yuanshen; yuanshen is generally harvested after 6-7 years of cultivation, is sweet, slightly bitter and warm in taste, enters lung, spleen, heart and kidney meridians and is mainly used for treating: invigorating primordial qi, restoring pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production, nourishing blood, tranquilizing mind, and improving intelligence, and can be used for treating asthenia, weak limbs, slight cold pulse, spleen deficiency, anorexia, cough and asthma due to lung deficiency, thirst due to body fluid consumption, internal heat, diabetes, deficiency of qi and blood, asthenia due to chronic diseases, palpitation, insomnia, sexual impotence, and cold womb.

Licorice root: is the dried root and rhizome of leguminous plant, glycyrrhiza siSFiSch, glycyrrhiza inflata G.inflataBat or glycyrrhiza glabra G.glabra L, collected in the second spring and autumn, collected in the above autumn, sweet and flat in taste, heart-entering, lung, spleen and stomach channels, and mainly treats: invigorating spleen and replenishing qi, eliminating phlegm and relieving cough, relieving spasm and pain, clearing heat and detoxicating, and harmonizing the drugs, and can be used for treating weakness of spleen and stomach, listlessness and debilitation, cardiopalmus and short breath, cough with excessive phlegm, abdominal and limbs spasm and pain, carbuncle and swelling, and sore, and relieving drug toxicity, and strong nature.

Black nightshade: the solanaceae solanum nigrum is full-grass, bitter and cold, has the functions of clearing heat, removing toxicity, promoting blood circulation and removing blood stasis, has an inhibiting effect on the tumor strains when being applied to mice inoculated with tumor cells such as ehrlich ascites carcinoma, lymphatic leukemia 615, sarcoma S180, sarcoma S37 and the like, and has the main treatment effects: it is used clinically to treat tongue cancer, larynx cancer, vocal cord cancer, nasopharyngeal carcinoma, cancerous ascites and chest cancer, esophagus cancer, stomach cancer, rectal cancer, liver cancer, etc.

Herba Lobeliae chinensis: is a plant of Campanulaceae, the whole herb with root of Chinese lobelia, is sweet, bland and cold, has the functions of clearing away heat and toxic material, inducing diuresis and reducing edema, and is tested in vitro: the results are screened by a Hela cell monolayer culture method, and the Chinese lobelia has anticancer activity; in vivo test: the product has effect in inhibiting mouse sarcoma S37; the heminelumbinis alkali has an inhibiting effect on cancer cells and is mainly used for treating: it is commonly used for treating lung cancer, liver cancer, gastric cancer, intestinal cancer, esophageal cancer, and laryngeal cancer.

Paclitaxel: a natural anticancer drug, molecular formula is C47H51N014, has been widely used in the treatment of breast cancer, ovarian cancer and partial head and neck cancer and lung cancer in clinic, paclitaxel is used as a diterpenoid alkaloid compound with anticancer activity, the lung septal day examination of inhaled male SD rat shows that the alveolar septal thickness is thin (P < 0.01), the expression levels of l, lll, collagen and TGF-Bl are all obviously reduced (P < 0.01), the conclusion is that: the paclitaxel liposome aerosol inhalation has obvious protective effect on pulmonary fibrosis of rats induced by bleomycin, and can reduce alveolitis, lung cell destruction degree and fibrosis degree, thereby reducing the death rate of rats.

Disclosure of Invention

Technical problem to be solved

Aiming at the defects of the prior art, the invention uses the Chinese herbal medicine anticancer smoking product to replace cigarettes, so that smokers are completely free from the harm of tobacco, and the wish of the health of the whole people is fulfilled.

(II) technical scheme

In order to achieve the purpose, the invention is realized by the following technical scheme: a method for preparing Chinese herbal medicine anticancer inhalation comprises the following steps:

s1, selecting materials: respectively selecting materials from barks and leaves of taxus chinensis, stems and leaves of fennel, lindera glauca, liquorice, solanum nigrum, agrimony, oldenlandia diffusa, Chinese lobelia, ginseng, jute, ganoderma lucidum and eucommia ulmoides, removing impurities from 12 medicinal materials, and packaging;

s2, extraction: respectively feeding the packaged medicinal materials into a filling bin, extracting 12 medicinal materials at high temperature, and feeding the extracted liquid into a quick freezing chamber for storage;

s3, baking: the dregs of the 12 medicinal materials after extraction are dehydrated, and the baking temperature is set to be 80-120 ℃ and the dregs are scorched for 3 hours;

s4, crushing: crushing the dehydrated slag into powder with the granularity of more than 120 meshes;

s5, slurry mixing: pouring 60% of the selected powder, 20% of the plant fiber, 10% of the plant glue, 3% of the combustion improver, 2% of the mildew preventive and 5% of the aroma-enhancing extract into a stirrer, and fully and uniformly stirring the mixture into a paste state;

s6, preparing tablets: feeding the insoluble particles stirred into a paste state into a sheet making device, and forming the sheet by using a rolling method;

s7, baking again: feeding the formed slices into microwave equipment, baking and dehydrating the slices again to form slices;

s8, shredding: the sheet is cut into filaments of 1mm width and 8 to 10mm length;

s9, puffing: the silk is sent into a puffing device, and the water content of the silk is set to be 11-12%;

s10, fragrance spraying: filling the quick-frozen plant spice into the shreds;

s11, tainting odor: and (3) sealing the silk sprayed with the fragrance in a sealing device for 7-10 days, so that all the silk is fully mixed with the fragrance, and the taste of each silk is consistent when the silk is sucked.

Preferably, the auxiliary materials comprise a flavoring agent, a humectant, a combustion improver, a mildew preventive, a coloring agent, and the auxiliary materials comprise the following ingredients in parts by mass, namely sugar coating, paraffin, plant fiber and plant glue.

Preferably, the anti-cancer liquid medicine is thawed, and in order to ensure the effect of the Chinese herbal medicine anti-cancer inhalant, the liquid extracted from the 12 Chinese herbal medicines is quickly frozen into the ice cream, so that the frozen water cream is taken out and dissolved into the liquid for later use at the constant temperature of 26-30 ℃.

Preferably, the liquid obtained by supercritical extraction of 12 Chinese medicinal materials is reasonably prepared into an anticancer liquid medicine through scientific technology, the liquid medicine is wrapped into the blasting beads through sugar coating and paraffin, the blasting beads are woven into the liquid medicine when a smoking article filter is processed, a smoker pinches the blasting beads before smoking to enable the medicine to flow into filter cotton, smoke generated during smoking of the smoker can be brought into the lung through the filter cotton, and the drug capillary vessels of the lung can fully absorb the curative effect of the anticancer medicine to achieve the effect of killing cancer cells.

Preferably, the Chinese herbal medicine anti-cancer smoking product is similar to a cigarette non-tobacco product.

(III) advantageous effects

The invention provides a method for preparing a Chinese herbal medicine anticancer inhalation, which has the following beneficial effects: the invention discloses a process flow of a Chinese herbal medicine anti-cancer smoking article manufacturing method, which keeps the pharmacological formula secret, and can be used as a basis for converting the technology into productivity, adjusting taste, treating effect, clinical healing report and the like.

Drawings

FIG. 1 is a process flow chart of the manufacturing method of a Chinese herbal medicine anticancer drug of the invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1:

the invention relates to a method for preparing a Chinese herbal medicine anticancer drug, which comprises the following steps:

s1, selecting materials: respectively selecting raw materials of taxus bark and leaves, fennel stems and leaves, lindera glauca leaves, liquorice, black nightshade, hairyvein agrimony, oldenlandia diffusa, Chinese lobelia, ginseng, jute, ganoderma lucidum and eucommia, removing impurities from 12 medicinal materials, and packaging;

s2, extraction: respectively feeding the packaged medicinal materials into a filling bin, extracting 12 medicinal materials at high temperature, and delivering the extracted liquid into a quick freezing chamber for storage;

s3, baking: dehydrating the residue of the 12 medicinal materials, and baking at 80-120 deg.C for 3 hr to brown;

s5, slurry mixing: pouring 60% of powder, 20% of plant fiber, 10% of plant glue, 3% of combustion improver, 2% of mildew preventive and 5% of aroma-enhancing extract into a stirrer, and fully and uniformly stirring the mixture into a paste state;

s8, shredding: cutting the sheet into filaments 1mm wide and 8 to 10mm long;

s9, puffing: feeding the silk into a puffing device, setting the water content of the silk to be 11-12%;

s10, fragrance spraying: then the plant spice which is quickly frozen during extraction is reversely filled into the shreds;

s11, tainting odor: and (3) sealing the fragrant silks in a sealing device for 7-10 days, so that all silks are fully mixed with the flavor, the taste of each silk is consistent when the silks are sucked, and the production and the manufacture of the anti-cancer sucking products are facilitated.

Furthermore, the auxiliary materials comprise flavoring agents, humectants, combustion improvers, mildewproof agents, coloring agents, sugar coatings, paraffin, plant fibers and plant glue, and the auxiliary materials can increase the anticancer efficiency.

Furthermore, the anti-cancer liquid medicine is unfrozen, in order to ensure the effect of the Chinese herbal medicine anti-cancer suction product, the liquid extracted from the 12 Chinese herbal medicines is quickly frozen into the ice cream, so that the frozen water cream is taken out and dissolved into liquid for later use at the constant temperature of 26-30 ℃, and the efficiency of the anti-cancer suction product is improved.

Furthermore, the liquid extracted by supercritical extraction from 12 Chinese medicinal materials is reasonably prepared into anticancer liquid medicine through scientific technology, the liquid medicine is wrapped into exploded beads through sugar coating and paraffin, the exploded beads are woven into the filter tip when the filter tip is processed, the exploded beads are pinched and broken by a smoker before smoking, the medicine flows into filter tip cotton, smoke generated by the smoker during smoking can bring medicine properties into the lung through the filter tip cotton, and the curative effect of the anticancer medicine is fully absorbed by capillary vessels of the lung, so that the effect of killing cancer cells is achieved, and the Chinese medicinal composition is convenient to use.

Furthermore, the Chinese herbal medicine anticancer smoking product is similar to a cigarette non-tobacco product.

In summary, the following steps: the invention relates to a method for preparing Chinese herbal medicine anticancer smoking article, which is characterized in that 12 Chinese herbal medicines are selected for years, after deep thought and fine selection, the selected Chinese herbal medicines have certain anticancer effect completely, the result obtained by a plurality of white rat experiments and clinic results is that the liquid medicine is atomized and enters the lung to completely inhibit the growth of cancer cells, the paclitaxel liposome atomization inhalation has obvious protective effect on pulmonary fibrosis of rats induced by bleomycin, the alveolitis, the destruction degree and the fibrosis degree of the lung cells can be reduced, the death rate is reduced, secondly, a smoker pinches off the blasting beads before smoking, the anticancer liquid medicine flows into filter cotton, when the smoker takes out smoke, the smoke can bring medicine property into the lung through the filter cotton, the curative effect of the anticancer medicine is fully absorbed by capillary vessels of the lung, the effect of killing the cancer cells is achieved, the function of the mouth of the smoking article is mainly embodied, the smoker can fully suck the smoking article containing the medicine property in the smoking process, ensures that the medicament can fully exert the due effect thereof and makes great contribution to the human health.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A method for preparing Chinese herbal medicine anticancer inhalation, which is characterized in that: the method comprises the following steps:

s10, fragrance spraying: filling the quick-frozen plant spice into the shreds;

2. The method for preparing Chinese herbal medicine anticancer inhalant according to claim 1, wherein the method comprises the following steps: the auxiliary materials comprise flavoring agents, humectants, combustion promoters, mildew preventives, coloring agents and ingredients with the following mass portions of sugar coatings, paraffin, plant fibers and plant glue.

3. The method for preparing Chinese herbal medicine anticancer inhalant according to claim 1, wherein the method comprises the following steps: the anti-cancer liquid medicine is thawed, and in order to ensure the effect of the Chinese herbal medicine anti-cancer inhalation product, the liquid extracted from the 12 Chinese herbal medicines is quickly frozen into the ice cream, and the frozen water cream is taken out and dissolved into liquid for later use at the constant temperature of 26-30 ℃.

4. The method for preparing Chinese herbal medicine anticancer inhalant according to claim 1, wherein the method comprises the following steps: the liquid extracted by supercritical extraction from 12 Chinese medicinal materials is formulated into anticancer liquid medicine through scientific technology, the liquid medicine is wrapped into exploded beads through sugar coating and paraffin, the exploded beads are woven into the filter tip during processing of an absorption product, the exploded beads are pinched by a smoker before smoking, the medicine flows into the filter tip cotton, the smoke of the smoker can bring medicine properties into the lung through the filter tip cotton, the curative effect of the anticancer medicine is fully absorbed by the capillary vessels of the lung, and the effect of killing cancer cells is achieved.

5. The method for preparing Chinese herbal medicine anticancer inhalant according to claim 1, wherein the method comprises the following steps: the Chinese herbal medicine anticancer smoking product is similar to a cigarette non-tobacco product.