CN112881256B - Oxygen permeability detection device for hollow capsules - Google Patents
Oxygen permeability detection device for hollow capsules Download PDFInfo
- Publication number
- CN112881256B CN112881256B CN202011604426.XA CN202011604426A CN112881256B CN 112881256 B CN112881256 B CN 112881256B CN 202011604426 A CN202011604426 A CN 202011604426A CN 112881256 B CN112881256 B CN 112881256B
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- Prior art keywords
- capsule
- flow
- oxygen
- sealing cavity
- sealing
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- 239000002775 capsule Substances 0.000 title claims abstract description 108
- 239000001301 oxygen Substances 0.000 title claims abstract description 72
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 72
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 69
- 230000035699 permeability Effects 0.000 title claims abstract description 27
- 238000001514 detection method Methods 0.000 title claims abstract description 24
- 238000007789 sealing Methods 0.000 claims abstract description 68
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 66
- 239000007921 spray Substances 0.000 claims abstract description 36
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 31
- 238000005192 partition Methods 0.000 claims abstract description 13
- 229910001873 dinitrogen Inorganic materials 0.000 claims description 5
- 238000003825 pressing Methods 0.000 claims description 2
- 238000005086 pumping Methods 0.000 claims 4
- 238000005507 spraying Methods 0.000 claims 4
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 1
- 229910001882 dioxygen Inorganic materials 0.000 claims 1
- 238000007599 discharging Methods 0.000 claims 1
- 230000009286 beneficial effect Effects 0.000 abstract description 4
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 238000005056 compaction Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/08—Investigating permeability, pore-volume, or surface area of porous materials
- G01N15/0806—Details, e.g. sample holders, mounting samples for testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/08—Investigating permeability, pore-volume, or surface area of porous materials
- G01N15/082—Investigating permeability by forcing a fluid through a sample
- G01N15/0826—Investigating permeability by forcing a fluid through a sample and measuring fluid flow rate, i.e. permeation rate or pressure change
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Fluid Mechanics (AREA)
- Accommodation For Nursing Or Treatment Tables (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Abstract
The invention discloses an oxygen permeability detection device for hollow capsules, which comprises a sealing box body, a sealing partition plate, an oxygen flow sealing cavity, a nitrogen flow sealing cavity, a capsule limiting groove, a capsule tightening convex ring, a capsule tightening groove, a capsule tightening cover plate, a splicing sealing cavity, an electric lifting seat, an electric telescopic nitrogen spray pipe, an air flow outlet, an air flow sensor, an oxygen flow spray plate, a branch spray pipe, an oxygen flow discharge plate and a control center. The device can automatically detect the oxygen permeability of the hollow capsule, has accurate detection result, convenient operation and high detection efficiency, and is beneficial to subsequent adjustment and control of the oxygen permeability of the hollow capsule.
Description
[ Field of technology ]
The invention relates to the technical field of capsule detection, in particular to the technical field of an oxygen permeability detection device for a hollow capsule.
[ Background Art ]
The oxygen permeability is one of the important parameter indexes of the hollow capsule, and oxygen can cause certain medicines to be oxidized and deteriorate, so that the oxygen permeability of the hollow capsule directly affects the safety and stability of the medicines. The hollow capsule with low oxygen permeability can protect the internal filling from oxidation, prolong the storage period and improve the stability of the medicine. Therefore, the method is particularly important for detecting the oxygen permeability of the empty capsules.
[ Invention ]
The invention aims to solve the problems in the prior art, and provides an oxygen permeability detection device for hollow capsules, which can automatically detect the oxygen permeability of the hollow capsules, has accurate detection results, is convenient to operate, has high detection efficiency, and is beneficial to subsequent adjustment and control of the oxygen permeability of the hollow capsules.
In order to achieve the above purpose, the invention provides an oxygen permeability detection device for hollow capsules, comprising a sealing box body, a sealing baffle plate, an oxygen flow sealing cavity, a nitrogen flow sealing cavity, a capsule limiting groove, a capsule tightening convex ring, a capsule tightening groove, a capsule tightening cover plate, a splicing sealing cavity, an electric lifting seat, an electric telescopic nitrogen spray pipe, an air flow outlet, an air flow sensor, an oxygen flow spray plate, a branch spray pipe, an oxygen flow discharge plate and a control center, wherein the middle part of the sealing box body is transversely provided with the sealing baffle plate, the sealing baffle plate divides the sealing box body into the oxygen flow sealing cavity and the nitrogen flow sealing cavity, a plurality of capsule limiting grooves are uniformly arranged on the sealing baffle plate in a penetrating way, the bottom of the outer side surface of the capsule limiting groove is circumferentially provided with a capsule tightening convex ring, the outer side of the capsule tightening convex ring is correspondingly sleeved with the capsule tightening groove, the capsule compresses tightly the recess and runs through the setting in the capsule compresses tightly the apron, the capsule compresses tightly the apron and passes through fixing bolt demountable installation at sealed baffle top, the below of capsule spacing groove is provided with the concatenation seal chamber, the bottom in concatenation seal chamber passes through electric lift seat and installs in the nitrogen flow seal chamber, be provided with electric telescopic nitrogen spray tube in the concatenation seal chamber, the inboard bottom in concatenation seal chamber is provided with the air current discharge port, the cover is equipped with the air current inductor on the air current discharge port, the top in capsule spacing groove is provided with the oxygen flow and spouts the board, the bottom of oxygen flow spouts the board is provided with a plurality of branch spouts just facing the capsule spacing groove, be provided with a plurality of oxygen flow discharge plates on the lateral wall of oxygen flow seal chamber, the top of seal box is provided with the control center, the control center respectively with concatenation seal chamber, electric lift seat, the electric telescopic nitrogen spray pipe, the air flow outlet, the air flow sensor, the oxygen flow spray plate and the oxygen flow outlet plate are connected one by one.
Preferably, a capsule guiding cambered surface is arranged at the top of the outer side surface of the capsule limiting groove.
Preferably, an elastic sealing ring is arranged at the inner side of the capsule pressing groove corresponding to the position of the capsule supporting convex ring.
Preferably, the number of the capsule limiting grooves is multiple, and the capsule limiting grooves are uniformly and vertically distributed on the sealing partition plate.
Preferably, the top end of the electric telescopic nitrogen spray pipe is provided with a distance sensor, and the distance sensor is connected with the control center.
Preferably, the sealing partition plate is provided with an air guide electromagnetic valve, the nitrogen flow sealing cavity is internally provided with a vacuumizing mechanism, the vacuumizing mechanism is connected with the air guide electromagnetic valve, the oxygen flow sealing cavity and the nitrogen flow sealing cavity are internally provided with air pressure sensors, the air pressure sensors are connected with the vacuumizing mechanism, and the air guide electromagnetic valve, the vacuumizing mechanism and the air pressure sensors are respectively connected with the control center.
Preferably, a self-locking universal wheel is arranged at the bottom of the sealing box body.
The invention has the beneficial effects that: according to the invention, the sealing box body, the sealing partition plate, the oxygen flow sealing cavity, the nitrogen flow sealing cavity, the capsule limiting groove, the capsule tightening convex ring, the capsule compacting groove, the capsule compacting cover plate, the splicing sealing cavity, the electric lifting seat, the electric telescopic nitrogen spray pipe, the air flow outlet, the air flow sensor, the oxygen flow spray plate, the branch spray pipe, the oxygen flow outlet plate and the control center are combined together, and through experimental optimization, the device can automatically detect the oxygen permeability of the hollow capsule, the detection result is accurate, the operation is convenient, the detection efficiency is high, and the subsequent adjustment and control of the oxygen permeability of the hollow capsule are facilitated.
The features and advantages of the present invention will be described in detail by way of example with reference to the accompanying drawings.
[ Description of the drawings ]
Fig. 1 is a schematic structural view of an oxygen permeability detection device for a hollow capsule according to the present invention.
In the figure: the device comprises a 1-sealed box body, a 2-sealed partition plate, a 3-oxygen flow sealing cavity, a 4-nitrogen flow sealing cavity, a 5-capsule limiting groove, a 6-capsule tightening convex ring, a 7-capsule tightening groove, an 8-capsule tightening cover plate, a 9-spliced sealing cavity, a 10-electric lifting seat, a 11-electric telescopic nitrogen spray pipe, a 12-air flow outlet, a 13-air flow sensor, a 14-oxygen flow spray plate, a 15-branch spray pipe, a 16-oxygen flow outlet plate, a 17-control center, a 18-capsule guiding cambered surface, a 19-distance sensor, a 20-air guide electromagnetic valve, a 21-vacuumizing mechanism and a 22-air pressure sensor.
[ Detailed description ] of the invention
Referring to fig. 1, the oxygen permeability detection device for hollow capsules of the invention comprises a sealed box body 1, a sealing partition plate 2, an oxygen flow sealing cavity 3, a nitrogen flow sealing cavity 4, a capsule limiting groove 5, a capsule tightening convex ring 6, a capsule tightening groove 7, a capsule tightening cover plate 8, a splicing sealing cavity 9, an electric lifting seat 10, an electric telescopic nitrogen spray pipe 11, an air flow discharge port 12, an air flow sensor 13, an oxygen flow spray plate 14, a branch spray pipe 15, an oxygen flow discharge plate 16 and a control center 17, wherein the sealing partition plate 2 is transversely arranged in the middle of the sealed box body 1, the sealing partition plate 2 divides the sealed box body 1 into the oxygen flow sealing cavity 3 and the nitrogen flow sealing cavity 4, a plurality of capsule limiting grooves 5 are uniformly and penetratingly arranged on the sealing partition plate 2, the capsule tightening convex ring 6 is circumferentially arranged at the bottom of the outer side surface of the capsule limiting groove 5, the outside of the capsule supporting convex ring 6 is correspondingly sleeved with a capsule compressing groove 7, the capsule compressing groove 7 is arranged in a capsule compressing cover plate 8 in a penetrating way, the capsule compressing cover plate 8 is detachably arranged at the top of the sealing partition plate 2 through a fixing bolt, a splicing sealing cavity 9 is arranged below the capsule limiting groove 5, the bottom end of the splicing sealing cavity 9 is arranged in the nitrogen flow sealing cavity 4 through an electric lifting seat 10, an electric telescopic nitrogen spray pipe 11 is arranged in the splicing sealing cavity 9, the bottom of the inner side of the splicing sealing cavity 9 is provided with an air flow outlet 12, an air flow sensor 13 is sleeved on the air flow outlet 12, an oxygen flow spray plate 14 is arranged above the capsule limiting groove 5, a plurality of branch spray pipes 15 which are opposite to the capsule limiting groove 5 are arranged at the bottom of the oxygen flow spray plate 14, a plurality of oxygen flow discharge plates 16 are arranged on the side wall of the oxygen flow sealing cavity 3, the top of sealed box 1 is provided with and controls the center 17, control the center 17 respectively with concatenation seal chamber 9, electric lift seat 10, electric telescopic nitrogen gas spray tube 11, air current discharge port 12, air current inductor 13, oxygen flow spray plate 14 and oxygen flow discharge plate 16 link to each other one by one, the lateral surface top of capsule spacing groove 5 is provided with capsule guide cambered surface 18, the inboard of capsule compaction groove 7 is provided with the elastic seal ring corresponding to capsule tight bulge loop 6 position, the quantity of capsule spacing groove 5 has a plurality of, capsule spacing groove 5 evenly vertical distribution is on sealed baffle 2, the top of electric telescopic nitrogen gas spray tube 11 is provided with apart from inductor 19, apart from inductor 19 and control the center 17 and link to each other, be provided with air guide solenoid valve 20 on the sealed baffle 2, be provided with evacuating mechanism 21 in the nitrogen flow seal chamber 4, evacuating mechanism 21 links to each other with air guide solenoid valve 20, all be provided with atmospheric pressure inductor 22 in oxygen flow seal chamber 3 and the nitrogen flow seal chamber 4, atmospheric pressure inductor 22 links to each other with evacuating mechanism 21, evacuating mechanism 20, air guide valve 21, 17 are provided with the universal wheel that the universal joint is controlled to the bottom of the sealed box 1 respectively.
According to the invention, the sealing box body 1, the sealing partition plate 2, the oxygen flow sealing cavity 3, the nitrogen flow sealing cavity 4, the capsule limiting groove 5, the capsule tightening convex ring 6, the capsule tightening groove 7, the capsule tightening cover plate 8, the splicing sealing cavity 9, the electric lifting seat 10, the electric telescopic nitrogen spray pipe 11, the air flow discharge port 12, the air flow sensor 13, the oxygen flow spray plate 14, the branch spray pipe 15, the oxygen flow discharge plate 16 and the control center 17 are combined together, and through experimental optimization, the device can automatically detect the oxygen permeability of the hollow capsule, and has the advantages of accurate detection result, convenient operation and high detection efficiency, and is beneficial to subsequent adjustment and control of the oxygen permeability of the hollow capsule.
The above embodiments are illustrative of the present invention, and not limiting, and any simple modifications of the present invention fall within the scope of the present invention.
Claims (7)
1. An oxygen permeability detection device of hollow capsule, its characterized in that: including seal box (1), seal baffle (2), oxygen flow seal chamber (3), nitrogen flow seal chamber (4), capsule spacing groove (5), capsule prop up bulge loop (6), capsule compress tightly recess (7), capsule compress tightly apron (8), concatenation seal chamber (9), electric lift seat (10), electric telescopic nitrogen spray pipe (11), air current discharge port (12), air current inductor (13), oxygen flow spray plate (14), branch spray pipe (15), oxygen flow discharge plate (16) and control center (17), seal baffle (2) have been transversely placed in the middle part of seal box (1), seal baffle (2) separate seal box (1) into oxygen flow seal chamber (3) and nitrogen flow seal chamber (4), even run through on seal baffle (2) and be provided with a plurality of capsule spacing groove (5), the outside face bottom of capsule spacing groove (5) is encircleed and is provided with capsule prop up bulge loop (6), the outside of capsule prop up bulge loop (6) corresponds the cover and is equipped with capsule compress tightly recess (7), capsule compress tightly recess (7) run through and set up in capsule (8) and install seal bolt (8) through seal bolt (8) at the top of dismantling, the capsule is characterized in that a splicing sealing cavity (9) is arranged below the capsule limiting groove (5), the bottom end of the splicing sealing cavity (9) is arranged in the nitrogen flow sealing cavity (4) through an electric lifting seat (10), an electric telescopic nitrogen spray pipe (11) is arranged in the splicing sealing cavity (9), an air flow outlet (12) is arranged at the bottom of the inner side of the splicing sealing cavity (9), an air flow sensor (13) is sleeved on the air flow outlet (12), an oxygen flow spraying plate (14) is arranged above the capsule limiting groove (5), a plurality of branch spray pipes (15) which are right opposite to the capsule limiting groove (5) are arranged at the bottom of the oxygen flow spraying plate (14), a plurality of oxygen flow discharging plates (16) are arranged on the side wall of the oxygen flow sealing cavity (3), and an operation center (17) is arranged at the top of the sealing box (1) and is respectively connected with the splicing sealing cavity (9), the electric lifting seat (10), the electric telescopic nitrogen spray pipes (11), the air flow outlet (12), the air flow sensor (13) and the oxygen flow spraying plate (14) and the oxygen flow spraying plate (16) are connected.
2. The oxygen permeability detection apparatus for empty capsules as claimed in claim 1, wherein: the top of the outer side surface of the capsule limiting groove (5) is provided with a capsule guiding cambered surface (18).
3. The oxygen permeability detection apparatus for empty capsules as claimed in claim 1, wherein: an elastic sealing ring is arranged on the inner side of the capsule pressing groove (7) corresponding to the position of the capsule supporting convex ring (6).
4. The oxygen permeability detection apparatus for empty capsules as claimed in claim 1, wherein: the number of the capsule limiting grooves (5) is multiple, and the capsule limiting grooves (5) are uniformly and vertically distributed on the sealing partition plate (2).
5. The oxygen permeability detection apparatus for empty capsules as claimed in claim 1, wherein: the top of the electric telescopic nitrogen spray pipe (11) is provided with a distance sensor (19), and the distance sensor (19) is connected with the control center (17).
6. The oxygen permeability detection apparatus for empty capsules as claimed in claim 1, wherein: the novel nitrogen gas vacuum pump is characterized in that an air guide electromagnetic valve (20) is arranged on the sealing partition plate (2), a vacuum pumping mechanism (21) is arranged in the nitrogen gas flow sealing cavity (4), the vacuum pumping mechanism (21) is connected with the air guide electromagnetic valve (20), air pressure sensors (22) are arranged in the oxygen gas flow sealing cavity (3) and the nitrogen gas flow sealing cavity (4), the air pressure sensors (22) are connected with the vacuum pumping mechanism (21), and the air guide electromagnetic valve (20), the vacuum pumping mechanism (21) and the air pressure sensors (22) are respectively connected with the control center (17).
7. The oxygen permeability detection apparatus for empty capsules as claimed in claim 1, wherein: the bottom of the sealing box body (1) is provided with a self-locking universal wheel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011604426.XA CN112881256B (en) | 2020-12-30 | 2020-12-30 | Oxygen permeability detection device for hollow capsules |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011604426.XA CN112881256B (en) | 2020-12-30 | 2020-12-30 | Oxygen permeability detection device for hollow capsules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112881256A CN112881256A (en) | 2021-06-01 |
| CN112881256B true CN112881256B (en) | 2024-05-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011604426.XA Active CN112881256B (en) | 2020-12-30 | 2020-12-30 | Oxygen permeability detection device for hollow capsules |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112881256B (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0727655A1 (en) * | 1995-02-15 | 1996-08-21 | Georges H. Dr. Lyssy | Device and process for measuring oxygen permeability of a test piece |
| KR20120138468A (en) * | 2011-06-15 | 2012-12-26 | 성균관대학교산학협력단 | Method and apparatus for measuring transmission of water vapor and oxygen |
| CN105717022A (en) * | 2016-01-29 | 2016-06-29 | 广州标际包装设备有限公司 | Differential-pressure-method gas transmittance tester |
| CN205964493U (en) * | 2016-05-31 | 2017-02-22 | 浙江汇力胶囊有限公司 | Efficient capsule lock mould |
| CN108613915A (en) * | 2018-07-16 | 2018-10-02 | 济南兰光机电技术有限公司 | A kind of OTR oxygen transmission rate test device, system and method |
| CN111855535A (en) * | 2020-08-19 | 2020-10-30 | 广州西唐机电科技有限公司 | Side leakage prevention structure based on equal-pressure method gas transmission capacity test |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015066819A1 (en) * | 2013-11-08 | 2015-05-14 | Carlos Filipe | Method of stabilizing molecules without refrigeration using water soluble polymers and applications thereof in performing chemical reactions |
| US20170008694A1 (en) * | 2013-12-03 | 2017-01-12 | Biserkon Holdings Ltd. | Capsule and device for preparing beverages and method for producing the capsule |
-
2020
- 2020-12-30 CN CN202011604426.XA patent/CN112881256B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0727655A1 (en) * | 1995-02-15 | 1996-08-21 | Georges H. Dr. Lyssy | Device and process for measuring oxygen permeability of a test piece |
| KR20120138468A (en) * | 2011-06-15 | 2012-12-26 | 성균관대학교산학협력단 | Method and apparatus for measuring transmission of water vapor and oxygen |
| CN105717022A (en) * | 2016-01-29 | 2016-06-29 | 广州标际包装设备有限公司 | Differential-pressure-method gas transmittance tester |
| CN205964493U (en) * | 2016-05-31 | 2017-02-22 | 浙江汇力胶囊有限公司 | Efficient capsule lock mould |
| CN108613915A (en) * | 2018-07-16 | 2018-10-02 | 济南兰光机电技术有限公司 | A kind of OTR oxygen transmission rate test device, system and method |
| CN111855535A (en) * | 2020-08-19 | 2020-10-30 | 广州西唐机电科技有限公司 | Side leakage prevention structure based on equal-pressure method gas transmission capacity test |
Non-Patent Citations (1)
| Title |
|---|
| 氧气透过率试验仪校准方法研究;毛森等;《测试技术学报》;20191231;第第33卷卷(第第6期期);第480-482页 * |
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| CN112881256A (en) | 2021-06-01 |
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