CN112858274A - Rapid detection device for antibody and antigen - Google Patents

Rapid detection device for antibody and antigen Download PDF

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Publication number
CN112858274A
CN112858274A CN202110088844.6A CN202110088844A CN112858274A CN 112858274 A CN112858274 A CN 112858274A CN 202110088844 A CN202110088844 A CN 202110088844A CN 112858274 A CN112858274 A CN 112858274A
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CN
China
Prior art keywords
box body
detection
base
tank
wall
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Pending
Application number
CN202110088844.6A
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Chinese (zh)
Inventor
曹凌波
陈园力
杨廷亚
汪金凤
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Nanjing Bomino Biotechnology Co ltd
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Nanjing Bomino Biotechnology Co ltd
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Priority to CN202110088844.6A priority Critical patent/CN112858274A/en
Publication of CN112858274A publication Critical patent/CN112858274A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B1/00Cleaning by methods involving the use of tools
    • B08B1/30Cleaning by methods involving the use of tools by movement of cleaning members over a surface
    • B08B1/32Cleaning by methods involving the use of tools by movement of cleaning members over a surface using rotary cleaning members
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Engineering & Computer Science (AREA)
  • Brushes (AREA)

Abstract

The invention relates to the technical field of antibody and antigen detection, and discloses a rapid detection device for an antibody and an antigen, which comprises a base, wherein a box body is arranged above the base, supporting rods are fixedly arranged at four corners of the bottom of the box body, the supporting rods are fixedly arranged on the upper surface of the base, a rotary disc is arranged in the box body, a rotary rod is fixedly arranged at the center of the lower surface of the rotary disc, the lower end of the rotary rod is rotatably connected with the bottom of the box body through a first rolling bearing, the lower end of the rotary rod extends to the lower side of the box body and is fixedly provided with a rocking handle, a limiting mechanism is arranged between the rocking handle and the base, a plurality of uniformly distributed fixing seats are rotatably arranged on the circumferential wall of the rotary disc, a transparent detection tank is arranged on the fixing seats. This quick detection device of antibody and antigen not only can carry out the multiunit and detect the contrast, and is good to the cleaning performance of transparent detection jar moreover to the detection efficiency of antibody antigen has been improved.

Description

Rapid detection device for antibody and antigen
Technical Field
The invention relates to the technical field of antibody and antigen detection, in particular to a rapid detection device for an antibody and an antigen.
Background
At present, the breeding industry utilizes the injected vaccine to control the epidemic disease and becomes one of the important means, the antibody that daily monitoring produced after the injected vaccine also becomes one of the important means of detecting the morbidity condition, but need detect internal antibody of pig and antigen before giving the pig injected vaccine, the mode of detecting at present mainly comes the blood detection of pig through the reagent, judge through the change of colour, need use transparent glass to hold during the detection, it needs to wash and disinfect the glass again to detect another to detect one to detect, consequently, cause detection efficiency slow, increase staff's burden.
Wherein the patent number is CN209894708U, discloses a quick detection device for swine disease antibodies and antigens, which comprises a detection box, the upper end of the detection box is provided with an opening, the rear side of the upper end of the opening is connected with an upper end connecting cover through a hinge, the upper end of the interior of the detection box is provided with a support plate, the left side of the upper surface of the support plate is provided with a transparent detection tank, the bottom surface of the interior of the detection box is provided with a sewage box, the upper end inlet of the sewage box is connected with the outlet of the transparent detection tank through a conduit, the conduit connecting the sewage box and the transparent detection tank is provided with an electromagnetic valve, the left side of the upper surface of the support plate is uniformly provided with a reagent placing groove, the lower surface of the upper end connecting cover is provided with a rubber sealing ring and a water dispersing ring, the water dispersing ring is positioned at the inner side of the rubber sealing ring and corresponds to, the upper surface of washing liquid holds the case is equipped with the feeding post.
In the scheme, only a single transparent detection tank is adopted, and when more detection contrast is needed, the detection requirement cannot be met, so that the cleaning effect on the transparent detection tank is poor, and the detection efficiency of the antibody antigen is finally reduced.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a rapid detection device for antibodies and antigens, which can not only carry out multi-group detection comparison, but also has good cleaning effect on a transparent detection tank, thereby improving the detection efficiency of the antibodies and antigens, solving the problems that only a single transparent detection tank is adopted, the detection requirement cannot be met when more detection comparison is needed, the cleaning effect on the transparent detection tank is poor, and the detection efficiency of the antibodies and antigens is finally reduced.
(II) technical scheme
In order to achieve the purpose, the invention provides the following technical scheme: a rapid detection device for antibodies and antigens comprises a base, wherein a box body is arranged above the base, supporting rods are fixedly arranged at four corners of the bottom of the box body, the supporting rods are fixedly arranged on the upper surface of the base, a rotary disc is arranged in the box body, a rotary rod is fixedly arranged at the center of the lower surface of the rotary disc, the lower end of the rotary rod is rotatably connected with the bottom of the box body through a first rolling bearing, the lower end of the rotary rod extends to the lower part of the box body and is fixedly provided with a rocking handle, a limiting mechanism is arranged between the rocking handle and the base, a plurality of uniformly distributed fixing seats are rotatably arranged on the circumferential wall of the rotary disc, a transparent detection tank is arranged on the fixing seats, a pressing plate is elastically arranged on the left side of the top of the box body, a shell is fixedly arranged on the lower surface of the pressing plate, a motor is fixedly arranged in the shell, the lower extreme of rotatory pipe extends to the inside of box and is located the top of transparent detection jar, the fixed washing brush that is equipped with of pipe wall of rotatory pipe, the fixed storage water tank that is equipped with of left side wall of box, the top intercommunication of storage water tank is provided with the inlet tube, the tip of inlet tube extend to the inside of box and set up with the pipe wall intercommunication of rotatory pipe, the top right side of box is equipped with the opening, and the articulated apron that is provided with of opening part, the left side wall of box and correspond the department with the position of transparent detection jar and be equipped with the hand and stretch into the mouth.
Preferably, the side wall of fixing base is fixed and is equipped with the pivot, the one end that the fixing base was kept away from in the pivot is rotated through the lateral wall of second antifriction bearing and carousel and is connected, the axle wall activity of pivot has cup jointed torsion spring, torsion spring's both ends respectively with the lateral wall fixed connection of the lateral wall of fixing base and the lateral wall of carousel.
Preferably, the top of box and the equal vertical fixed spacing slide bar that is equipped with in the left and right sides that is located the clamp plate, the left and right sides of clamp plate all fixes and is equipped with spacing slider, two spacing slider's surface all through spacing slide hole and spacing slide bar's pole wall sliding connection, two spacing slide bar's the equal activity of pole wall has cup jointed the spring, the both ends of spring respectively with the top of box and spacing slider's downside fixed connection, two spacing slide bar's upper end all is fixed and is equipped with limit stop.
Preferably, a pressing pad is fixedly arranged on the upper surface of the pressing plate.
Preferably, stop gear includes spacing bolt and spacing snap ring, the lateral wall of rocking handle is offered and is used for the jack that spacing bolt passed, spacing snap ring is to encircle the fixed upper surface that is equipped with the base and sets up with the lower extreme joint of spacing bolt.
Preferably, a water collecting tank is fixedly arranged on the left side of the upper surface of the base, a water collecting pipe is communicated with the top of the water collecting tank, and the other end of the water collecting pipe is communicated with the bottom of the box body.
Preferably, the upper surface of the cover plate is fixedly provided with a U-shaped handle.
Preferably, the pipe wall of the rotating pipe is provided with a plurality of water outlet holes which are uniformly distributed.
(III) advantageous effects
Compared with the prior art, the invention provides a rapid detection device for antibodies and antigens, which has the following beneficial effects:
1. the rapid detection device for the antibody and the antigen comprises a turntable, a rotary rod, a rocking handle, a fixed seat, a transparent detection tank, a pressing plate, a shell, a motor, a rotary pipe, a cleaning brush, a water storage tank, a water inlet pipe, a cover plate, a limiting bolt and a limiting snap ring, wherein when a plurality of detection comparisons are needed, different antibodies and antigens are poured into the plurality of transparent detection tanks in sequence by a worker for detection, then corresponding detection reagents are added, the detection results of the antibodies and the antigens are observed through color changes, when the transparent detection tanks are needed to be cleaned, the worker takes the limiting bolt off the rocking handle and takes the lower end of the limiting bolt out of the limiting snap ring, then the rocking handle is rotated to enable the corresponding transparent detection tank on the turntable to move to be under the rotary pipe, then the pressing plate is pressed down by hands, so that the rotary pipe on the motor extends into the transparent detection tank and the motor is opened for work, the motor drives the washing brush rotation on the rotatory pipe and effectively washs the inside of transparent detection jar, opens the storage water tank simultaneously and makes its inside rivers flow into the inside of rotatory pipe to can carry out effectual washing with the inner wall of transparent detection jar.
2. This quick detection device of antibody and antigen, through the pivot that is equipped with, torsion spring, receive the water tank and receive the water pipe, can guarantee the fixing base angle rotation and pour out the inside washing water of transparent detection jar and trickle in the inside of receiving the water tank through receiving the water pipe, through the spacing slide bar that is equipped with, limit slide, spring and limit stop, when the clamp plate moves down, can make limit slide move and extrude the spring on limit slide's pole wall, when staff's hand left the clamp plate, receive extruded spring and exert ascending external force for the clamp plate and make the washing brush on the swivel pipe shift out from the inside automation of transparent detection jar this moment.
Drawings
FIG. 1 is a schematic structural diagram of an apparatus for rapid detection of antibodies and antigens according to the present invention;
FIG. 2 is an enlarged view of a portion A of FIG. 1;
fig. 3 is an enlarged view of a portion B in fig. 1.
In the figure: the device comprises a base 1, a box body 2, a supporting rod 3, a rotating disk 4, a rotating rod 5, a rocking handle 6, a fixed seat 7, a transparent detection tank 8, a pressing plate 9, a shell 10, a motor 11, a rotating pipe 12, a cleaning brush 13, a water storage tank 14, a water inlet pipe 15, a cover plate 16, a rotating shaft 17, a torsion spring 18, a limiting slide rod 19, a limiting slide block 20, a spring 21, a limiting stop 22, a limiting bolt 23, a limiting snap ring 24, a water collecting tank 25, a water collecting pipe 26, a lifting handle 27U-shaped and a water outlet 28.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-3, a rapid detection device for antibodies and antigens comprises a base 1, a box 2 is disposed above the base 1, support rods 3 are fixedly disposed at four corners of the bottom of the box 2, the support rods 3 are fixedly disposed on the upper surface of the base 1, a turntable 4 is disposed inside the box 2, a rotary rod 5 is fixedly disposed at the center of the lower surface of the turntable 4, the lower end of the rotary rod 5 is rotatably connected with the bottom of the box 2 through a first rolling bearing, the lower end of the rotary rod 5 extends to the lower side of the box 2 and is fixedly provided with a rocking handle 6, a limiting mechanism is disposed between the rocking handle 6 and the base 1, a plurality of uniformly distributed fixing seats 7 are rotatably disposed on the circumferential wall of the turntable 4, a transparent detection tank 8 is disposed on the fixing seats 7, a pressing plate 9 is elastically disposed on the left side of the top of the box 2, a pressing pad is fixedly disposed on the, casing 10's inside is fixed and is equipped with motor 11, motor 11's output shaft end runs through to casing 10's below and fixed and be equipped with rotatory pipe 12, the lower extreme of rotatory pipe 12 extends to box 2's inside and is located transparent detection jar 8's top, the fixed washing brush 13 that is equipped with of pipe wall of rotatory pipe 12, box 2's the fixed storage water tank 14 that is equipped with of left side wall, storage water tank 14's top intercommunication is provided with inlet tube 15, inlet tube 15's tip extend to box 2's inside and set up with rotatory pipe 12's pipe wall intercommunication, box 2's top right side is equipped with the opening, and the articulated apron 16 that is provided with of opening part, apron 16's last fixed surface is equipped with U type handle 27, box 2's left side wall just corresponds the department with transparent detection jar.
The fixed pivot 17 that is equipped with of lateral wall of fixing base 7, the one end that fixing base 7 was kept away from to pivot 17 is rotated through second antifriction bearing and is connected with the lateral wall of carousel 4, and torque spring 18 has been cup jointed in the axle wall activity of pivot 17, and torque spring 18's both ends respectively with the lateral wall of fixing base 7 and the lateral wall fixed connection of carousel 4.
The top of box 2 and the equal vertical fixed limit slide bar 19 that is equipped with in the left and right sides that is located clamp plate 9, the left and right sides of clamp plate 9 all fixes and is equipped with limit slide block 20, two limit slide block 20's surface all is through limit slide hole and limit slide bar 19's pole wall sliding connection, spring 21 has been cup jointed in the equal activity of two limit slide bar 19's pole wall, spring 21's both ends respectively with the top of box 2 and limit slide block 20's downside fixed connection, two limit slide bar 19's upper end is all fixed and is equipped with limit stop 22.
Limiting mechanism includes limiting bolt 23 and limiting snap ring 24, and the jack that is used for limiting bolt 23 to pass is seted up to the lateral wall of rocking handle 6, and limiting snap ring 24 is to encircle the fixed upper surface that is equipped with base 1 and sets up with the lower extreme joint of limiting bolt 23.
The upper surface left side of base 1 is fixed and is equipped with receipts water tank 25, and the top intercommunication of receiving water tank 25 is provided with receipts water pipe 26, and the other end of receiving water pipe 26 sets up with the bottom intercommunication of box 2.
The wall of the rotating pipe 12 is provided with a plurality of uniformly distributed water outlets 28, which can ensure that water is uniformly sprayed on the cleaning brush 13.
In conclusion, when a plurality of detection comparisons are needed, a worker pours different antibodies and antigens into the transparent detection tanks 8 in sequence for detection, adds corresponding detection reagents and observes the detection results of the antibodies and the antigens through color changes, when the transparent detection tanks 8 need to be cleaned, the worker takes the limit bolts 23 off the rocking handle 6 and takes the lower ends of the limit bolts 23 out of the limit inserting rings 24, rotates the rocking handle 6 to move the corresponding transparent detection tanks 8 on the rotary table 4 to be under the rotary pipe 12, then presses the pressing plate 9 by hands to enable the rotary pipes 12 on the motor 11 to extend into the transparent detection tanks 8 and open the motor 11 to work, the motor 11 drives the cleaning brushes 13 on the rotary pipe 12 to rotate and effectively clean the interiors of the transparent detection tanks 8, meanwhile, the water storage tank 14 is opened and water in the water storage tank flows into the rotating pipe 12, so that the inner wall of the transparent detection tank 8 can be effectively cleaned; through the arranged 17 rotating shaft, 18 torsion springs, the water collecting tank and 26 water collecting pipes, the hand of a worker can be ensured to stretch into the box body 2 and then the fixing seat 7 can rotate at an angle, cleaning water in the transparent detection tank 8 is poured out and flows into the water collecting tank 25 through the water collecting pipes 26, and when the hand of the worker leaves the fixing seat 7, the fixing seat 7 is automatically in a horizontal state under the action of the torsion springs 18, so that the transparent detection tank 8 is ensured to be in the horizontal state; when the pressure plate 9 moves downwards, the limiting slide block 20 moves on the rod wall of the limiting slide rod 19 and presses the spring 21, and when the hand of the worker leaves the pressure plate 9, the pressed spring 21 applies an upward external force to the pressure plate 9 and enables the cleaning brush 13 on the rotating pipe 12 to automatically move out of the interior of the transparent detection tank 8.
It is to be noted that the term "comprises," "comprising," or any other variation thereof is intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (8)

1. The utility model provides a quick detection device of antibody and antigen, includes base (1), its characterized in that: the improved multifunctional box is characterized in that a box body (2) is arranged above the base (1), supporting rods (3) are fixedly arranged at four corners of the bottom of the box body (2), the supporting rods (3) are fixedly arranged on the upper surface of the base (1), a rotary disc (4) is arranged inside the box body (2), a rotary rod (5) is fixedly arranged at the center of the lower surface of the rotary disc (4), the lower end of the rotary rod (5) is rotatably connected with the bottom of the box body (2) through a first rolling bearing, the lower end of the rotary rod (5) extends to the lower side of the box body (2) and is fixedly provided with a rocking handle (6), a limiting mechanism is arranged between the rocking handle (6) and the base (1), a plurality of uniformly distributed fixing seats (7) are rotatably arranged on the circumferential wall of the rotary disc (4), a transparent detection tank (8) is arranged on the fixing seats (7), and a pressing plate (9), a shell (10) is fixedly arranged on the lower surface of the pressure plate (9), a motor (11) is fixedly arranged inside the shell (10), the tail end of an output shaft of the motor (11) penetrates below the shell (10) and is fixedly provided with a rotating pipe (12), the lower end of the rotating pipe (12) extends to the interior of the box body (2) and is positioned above the transparent detection tank (8), the wall of the rotating pipe (12) is fixedly provided with a cleaning brush (13), the left side wall of the box body (2) is fixedly provided with a water storage tank (14), the top of the water storage tank (14) is communicated with a water inlet pipe (15), the end part of the water inlet pipe (15) extends into the tank body (2) and is communicated with the pipe wall of the rotary pipe (12), the right side of the top of the tank body (2) is provided with an opening, and the opening part is hinged with a cover plate (16), and the left side wall of the box body (2) and the position corresponding to the transparent detection tank (8) are provided with a hand stretching inlet.
2. The device for rapid detection of antibodies and antigens according to claim 1, wherein: the fixed pivot (17) that is equipped with of lateral wall of fixing base (7), the one end that fixing base (7) were kept away from in pivot (17) is rotated through the lateral wall of second antifriction bearing and carousel (4) and is connected, torsion spring (18) have been cup jointed in the axle wall activity of pivot (17), torsion spring (18) both ends respectively with the lateral wall of fixing base (7) and the lateral wall fixed connection of carousel (4).
3. The device for rapid detection of antibodies and antigens according to claim 1, wherein: the top of box (2) just is located the equal vertical fixed limit slide (19) that is equipped with in the left and right sides of clamp plate (9), the left and right sides of clamp plate (9) is all fixed and is equipped with limit slide (20), two the surface of limit slide (20) is all through the pole wall sliding connection of limit slide and limit slide (19), two spring (21) have all been cup jointed in the activity to the pole wall of limit slide (19), the both ends of spring (21) respectively with the top of box (2) and the downside fixed connection of limit slide (20), two limit slide (19)'s upper end is all fixed and is equipped with limit stop (22).
4. The device for rapid detection of antibodies and antigens according to claim 1, wherein: the upper surface of the pressing plate (9) is fixedly provided with a pressing pad.
5. The device for rapid detection of antibodies and antigens according to claim 1, wherein: stop gear includes spacing bolt (23) and spacing snap ring (24), the lateral wall of rocking handle (6) is seted up and is used for the jack that spacing bolt (23) passed, spacing snap ring (24) are around fixed upper surface that is equipped with base (1) and set up with the lower extreme joint of spacing bolt (23).
6. The device for rapid detection of antibodies and antigens according to claim 1, wherein: the water collecting tank is characterized in that a water collecting tank (25) is fixedly arranged on the left side of the upper surface of the base (1), a water collecting pipe (26) is communicated with the top of the water collecting tank (25), and the other end of the water collecting pipe (26) is communicated with the bottom of the tank body (2).
7. The device for rapid detection of antibodies and antigens according to claim 1, wherein: and a U-shaped handle (27) is fixedly arranged on the upper surface of the cover plate (16).
8. The device for rapid detection of antibodies and antigens according to claim 1, wherein: the pipe wall of the rotating pipe (12) is provided with a plurality of water outlet holes (28) which are uniformly distributed.
CN202110088844.6A 2021-01-22 2021-01-22 Rapid detection device for antibody and antigen Pending CN112858274A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110088844.6A CN112858274A (en) 2021-01-22 2021-01-22 Rapid detection device for antibody and antigen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110088844.6A CN112858274A (en) 2021-01-22 2021-01-22 Rapid detection device for antibody and antigen

Publications (1)

Publication Number Publication Date
CN112858274A true CN112858274A (en) 2021-05-28

Family

ID=76008037

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110088844.6A Pending CN112858274A (en) 2021-01-22 2021-01-22 Rapid detection device for antibody and antigen

Country Status (1)

Country Link
CN (1) CN112858274A (en)

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