CN112839653A - 使用曲司氯铵治疗膀胱过度活动症的方法 - Google Patents
使用曲司氯铵治疗膀胱过度活动症的方法 Download PDFInfo
- Publication number
- CN112839653A CN112839653A CN201980064872.5A CN201980064872A CN112839653A CN 112839653 A CN112839653 A CN 112839653A CN 201980064872 A CN201980064872 A CN 201980064872A CN 112839653 A CN112839653 A CN 112839653A
- Authority
- CN
- China
- Prior art keywords
- trospium chloride
- days
- bladder
- day
- weeks
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0266—Shape memory materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1078—Urinary tract
- A61M2210/1085—Bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862713414P | 2018-08-01 | 2018-08-01 | |
| US62/713,414 | 2018-08-01 | ||
| US201962850481P | 2019-05-20 | 2019-05-20 | |
| US62/850,481 | 2019-05-20 | ||
| PCT/US2019/044478 WO2020028554A1 (en) | 2018-08-01 | 2019-07-31 | Methods of treating overactive bladder using trospium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112839653A true CN112839653A (zh) | 2021-05-25 |
Family
ID=69232612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980064872.5A Pending CN112839653A (zh) | 2018-08-01 | 2019-07-31 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11464734B2 (https=) |
| EP (1) | EP3829582A4 (https=) |
| JP (2) | JP2021532155A (https=) |
| KR (1) | KR20210039403A (https=) |
| CN (1) | CN112839653A (https=) |
| AU (1) | AU2019315957A1 (https=) |
| BR (1) | BR112021001337A2 (https=) |
| CA (1) | CA3107461A1 (https=) |
| MX (1) | MX2021001264A (https=) |
| WO (1) | WO2020028554A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT4124339T (lt) | 2014-03-06 | 2025-11-10 | Vaisto įvedimo sistemos ir būdai šlapimo pūslės vėžiui gydyti gemcitabinu | |
| BR112020000832A2 (pt) | 2017-07-25 | 2020-07-21 | Taris Biomedical Llc | métodos para tratar metástase tumoral |
| JOP20200124A1 (ar) | 2017-11-08 | 2020-05-20 | Taris Biomedical Llc | طُرق لعلاج سرطان المثانة باستخدام جيمسيتابين وعلاج مدوامة لذلك |
| CN112839653A (zh) | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5998430A (en) * | 1996-11-27 | 1999-12-07 | Dr. R. Pfleger Chemische Fabrik Gmbh | Use of trospium chloride and 2-component system for the same |
| WO2006101954A2 (en) * | 2005-03-17 | 2006-09-28 | Indevus Pharmaceuticals, Inc. | Interstitial cystitis treatment |
| EP2719374A1 (en) * | 2012-10-12 | 2014-04-16 | Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen | Drug delivery device |
| CN104640549A (zh) * | 2012-08-31 | 2015-05-20 | 塔里斯生物医药公司 | 用于治疗膀胱癌的药物递送系统和方法 |
| CN104684556A (zh) * | 2012-09-18 | 2015-06-03 | 塔里斯生物医药公司 | 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2013000002A (es) * | 2001-07-27 | 2013-04-29 | Teva Womens Health Inc | Metodos de tratamiento de condiciones patologicas asociadas con vejiga hiperactiva. |
| US20060058777A1 (en) | 2002-12-11 | 2006-03-16 | Pia Norup Nielsen | Urinary catheter device with a pharmaceutically active composition |
| WO2004064789A2 (en) | 2003-01-16 | 2004-08-05 | University Of Rochester | Quaternary antimuscarinic compounds for the treatment of bladder diseases |
| EP1703895A2 (en) * | 2004-01-13 | 2006-09-27 | Vasogenix Pharmaceuticals, Inc. | Controlled release cgrp delivery composition for cardiovascular and renal indications |
| ES2322148T3 (es) | 2004-08-11 | 2009-06-17 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | Medicamentos que contienen anticolinergicos para el tratamiento en las vias urinarias. |
| US20060128808A1 (en) | 2004-10-20 | 2006-06-15 | Galderma Research & Development, S.N.C. | Method of using adapalene in acne maintenance therapy |
| US7390816B2 (en) * | 2005-06-21 | 2008-06-24 | Bridge Pharma, Inc. | Methods for treating urinary incontinence in patients suffering from memory disorders |
| DK1933810T3 (da) | 2005-08-11 | 2013-01-28 | Childrens Medical Center | Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde |
| ES2365161T3 (es) | 2005-09-02 | 2011-09-23 | Theravida, Inc. | Terapia para el tratamiento de la vejiga hiperactiva. |
| EP1967202A1 (en) | 2007-03-05 | 2008-09-10 | AEterna Zentaris GmbH | Use of LHRH Antagonists for the Treatment of Lower Urinary Tract Symptoms, in particular Overactive Bladder and/or Detrusor Overactivity |
| KR101538748B1 (ko) | 2007-12-11 | 2015-07-22 | 메사추세츠 인스티튜트 오브 테크놀로지 | 이식형 의약 투여 장치와 방광과 기타 신체 낭 또는 내강의 치료 방법 |
| EA201170297A1 (ru) | 2008-08-09 | 2011-08-30 | Массачусетс Инститьют Оф Текнолоджи | Имплантируемое устройство для доставки лекарственных средств и способ лечения мужской мочеполовой системы и окружающих тканей |
| DK2445570T3 (da) | 2009-06-26 | 2013-02-25 | Taris Biomedical Inc | Implanterbare lægemiddelafgivelsesindretninger samt fremgangsmåder til deres fremstilling |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| PL3884988T3 (pl) | 2009-12-17 | 2025-09-08 | Taris Biomedical Llc | Urządzenie implantowalne z tolerancją wewnątrzpęcherzową |
| EP3795121A1 (en) | 2010-08-05 | 2021-03-24 | TARIS Biomedical LLC | Ureteral stent drug delivery device |
| WO2012048114A1 (en) | 2010-10-06 | 2012-04-12 | Taris Biomedical, Inc. | Time-selective bioresorbable or collapsible drug delivery systems and methods |
| JP2014503554A (ja) | 2011-01-10 | 2014-02-13 | タリス バイオメディカル,インコーポレイテッド | 膀胱痛及び刺激性排尿の持続的治療の使用のためのリドカインレジメン |
| EP2670398B1 (en) | 2011-02-04 | 2017-06-07 | TARIS Biomedical LLC | Implantable device for controlled release of low solubility drug |
| MX367070B (es) | 2012-08-31 | 2019-08-05 | Taris Biomedical Llc | Sistemas de administracion de farmaco y metodos para el tratamiento de la prostata. |
| JP2016508842A (ja) | 2013-03-05 | 2016-03-24 | タリス バイオメディカル エルエルシー | 装置の開口部を通じて制御された薬物放出のための薬物送達装置及び方法 |
| EP2968120B1 (en) | 2013-03-15 | 2026-01-14 | TARIS Biomedical LLC | Drug delivery devices and methods for drug delivery |
| KR102557326B1 (ko) | 2013-03-15 | 2023-07-19 | 타리스 바이오메디컬 엘엘씨 | 약물-투과성 구성요소를 가지는 약물 전달 장치 |
| KR102385603B1 (ko) | 2013-08-19 | 2022-04-11 | 타리스 바이오메디컬 엘엘씨 | 다중 유닛 약물 전달 장치 및 방법 |
| EP3065807A1 (en) | 2013-11-05 | 2016-09-14 | TARIS Biomedical LLC | Osmotic drug delivery devices, kits, and methods |
| LT4124339T (lt) | 2014-03-06 | 2025-11-10 | Vaisto įvedimo sistemos ir būdai šlapimo pūslės vėžiui gydyti gemcitabinu | |
| KR20220061253A (ko) | 2014-06-26 | 2022-05-12 | 타리스 바이오메디컬 엘엘씨 | 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법 |
| WO2016172704A1 (en) | 2015-04-23 | 2016-10-27 | Taris Biomedical Llc | Drug delivery devices with drug-permeable component and methods |
| US20190060407A1 (en) * | 2015-09-10 | 2019-02-28 | Assistance Publique - Hôpitaux De Paris | Use of interleukin 2 for treating spondyloarthritis |
| JP6283440B1 (ja) * | 2016-10-27 | 2018-02-21 | Eaファーマ株式会社 | 逆流性食道炎の再発抑制剤 |
| PT3432970T (pt) * | 2017-02-01 | 2021-05-26 | Taris Biomedical Llc | Dispositivos de administração de fármaco in vivo |
| BR112020000832A2 (pt) | 2017-07-25 | 2020-07-21 | Taris Biomedical Llc | métodos para tratar metástase tumoral |
| CN112839653A (zh) | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
-
2019
- 2019-07-31 CN CN201980064872.5A patent/CN112839653A/zh active Pending
- 2019-07-31 AU AU2019315957A patent/AU2019315957A1/en not_active Abandoned
- 2019-07-31 BR BR112021001337-7A patent/BR112021001337A2/pt unknown
- 2019-07-31 WO PCT/US2019/044478 patent/WO2020028554A1/en not_active Ceased
- 2019-07-31 EP EP19844186.7A patent/EP3829582A4/en active Pending
- 2019-07-31 CA CA3107461A patent/CA3107461A1/en active Pending
- 2019-07-31 KR KR1020217005331A patent/KR20210039403A/ko not_active Ceased
- 2019-07-31 MX MX2021001264A patent/MX2021001264A/es unknown
- 2019-07-31 JP JP2021504826A patent/JP2021532155A/ja active Pending
- 2019-07-31 US US16/528,032 patent/US11464734B2/en active Active
-
2022
- 2022-08-11 US US17/886,325 patent/US12133913B2/en active Active
-
2024
- 2024-07-26 JP JP2024121447A patent/JP2024164020A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5998430A (en) * | 1996-11-27 | 1999-12-07 | Dr. R. Pfleger Chemische Fabrik Gmbh | Use of trospium chloride and 2-component system for the same |
| WO2006101954A2 (en) * | 2005-03-17 | 2006-09-28 | Indevus Pharmaceuticals, Inc. | Interstitial cystitis treatment |
| CN104640549A (zh) * | 2012-08-31 | 2015-05-20 | 塔里斯生物医药公司 | 用于治疗膀胱癌的药物递送系统和方法 |
| CN104684556A (zh) * | 2012-09-18 | 2015-06-03 | 塔里斯生物医药公司 | 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法 |
| EP2719374A1 (en) * | 2012-10-12 | 2014-04-16 | Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen | Drug delivery device |
Non-Patent Citations (1)
| Title |
|---|
| HAUPT等: "Lipid-based intravesical drug delivery systems with controlled release of trospium chloride for the urinary bladder", JOURNAL OF CONTROLLED RELEASE, vol. 170, no. 2, pages 161 - 166, XP028676589, DOI: 10.1016/j.jconrel.2013.05.018 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021532155A (ja) | 2021-11-25 |
| US20230075003A1 (en) | 2023-03-09 |
| US12133913B2 (en) | 2024-11-05 |
| US11464734B2 (en) | 2022-10-11 |
| MX2021001264A (es) | 2021-07-02 |
| AU2019315957A1 (en) | 2021-02-18 |
| CA3107461A1 (en) | 2020-02-06 |
| EP3829582A1 (en) | 2021-06-09 |
| US20200060966A1 (en) | 2020-02-27 |
| WO2020028554A1 (en) | 2020-02-06 |
| JP2024164020A (ja) | 2024-11-26 |
| EP3829582A4 (en) | 2022-04-27 |
| BR112021001337A2 (pt) | 2021-04-20 |
| KR20210039403A (ko) | 2021-04-09 |
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