CN112815638A - Method for drying erythromycin thiocyanate fungus residues - Google Patents
Method for drying erythromycin thiocyanate fungus residues Download PDFInfo
- Publication number
- CN112815638A CN112815638A CN202011638548.0A CN202011638548A CN112815638A CN 112815638 A CN112815638 A CN 112815638A CN 202011638548 A CN202011638548 A CN 202011638548A CN 112815638 A CN112815638 A CN 112815638A
- Authority
- CN
- China
- Prior art keywords
- drying
- aqueous solution
- pressure
- stirring
- feeding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001035 drying Methods 0.000 title claims abstract description 48
- PGNYNCTUBKSHHL-UHFFFAOYSA-N 2,3-diaminobutanedioic acid Chemical compound OC(=O)C(N)C(N)C(O)=O PGNYNCTUBKSHHL-UHFFFAOYSA-N 0.000 title claims abstract description 34
- 241000233866 Fungi Species 0.000 title claims abstract description 31
- 238000000034 method Methods 0.000 title claims abstract description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 28
- 235000001674 Agaricus brunnescens Nutrition 0.000 claims abstract description 21
- 238000003825 pressing Methods 0.000 claims abstract description 16
- 239000007864 aqueous solution Substances 0.000 claims description 28
- 238000003756 stirring Methods 0.000 claims description 27
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 21
- 229920002401 polyacrylamide Polymers 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 5
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 4
- 239000008394 flocculating agent Substances 0.000 claims description 4
- 239000011259 mixed solution Substances 0.000 claims description 4
- 238000007602 hot air drying Methods 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 17
- 238000005265 energy consumption Methods 0.000 abstract description 6
- 239000002699 waste material Substances 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 230000003311 flocculating effect Effects 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 description 21
- 238000000855 fermentation Methods 0.000 description 8
- 230000004151 fermentation Effects 0.000 description 8
- 238000005189 flocculation Methods 0.000 description 8
- 230000016615 flocculation Effects 0.000 description 7
- 241000894006 Bacteria Species 0.000 description 5
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000002893 slag Substances 0.000 description 3
- 241000255925 Diptera Species 0.000 description 2
- 241000282414 Homo sapiens Species 0.000 description 2
- 238000007865 diluting Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229960003276 erythromycin Drugs 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 239000000543 intermediate Substances 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 239000013049 sediment Substances 0.000 description 2
- 239000002689 soil Substances 0.000 description 2
- RXZBMPWDPOLZGW-XMRMVWPWSA-N (E)-roxithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=N/OCOCCOC)/[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 RXZBMPWDPOLZGW-XMRMVWPWSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 235000019750 Crude protein Nutrition 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 241000204031 Mycoplasma Species 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- 229960004099 azithromycin Drugs 0.000 description 1
- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229960002626 clarithromycin Drugs 0.000 description 1
- AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 235000019784 crude fat Nutrition 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000002921 fermentation waste Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- 239000003120 macrolide antibiotic agent Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229960005224 roxithromycin Drugs 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 239000002910 solid waste Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 150000003567 thiocyanates Chemical class 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B7/00—Drying solid materials or objects by processes using a combination of processes not covered by a single one of groups F26B3/00 and F26B5/00
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B1/00—Preliminary treatment of solid materials or objects to facilitate drying, e.g. mixing or backmixing the materials to be dried with predominantly dry solids
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B3/00—Drying solid materials or objects by processes involving the application of heat
- F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/14—Drying solid materials or objects by processes not involving the application of heat by applying pressure, e.g. wringing; by brushing; by wiping
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Processing Of Solid Wastes (AREA)
- Drying Of Solid Materials (AREA)
Abstract
The invention provides a method for drying erythromycin thiocyanate mushroom dregs. Comprises the steps of flocculating the erythromycin thiocyanate fungus residue, filter-pressing by a plate frame and drying by hot air. The method has a very good drying effect, the water content of the dried erythromycin thiocyanate fungus residue is very low and is only 15-22%, high-temperature heat drying is avoided, energy consumption is reduced, waste is avoided, automation of the whole drying process can be realized, manpower is saved, and the cost is greatly reduced. The dried mushroom dregs with low water content are beneficial to further treatment, and the transportation cost and the treatment cost are reduced.
Description
Technical Field
The invention belongs to the field of post-treatment of biological pharmacy, and particularly relates to a method for drying erythromycin thiocyanate mushroom dregs.
Background
Erythromycin thiocyanate is a thiocyanate salt of erythromycin, is used for infection of gram-positive bacteria and mycoplasma, and can be directly used as veterinary antibiotic. In addition, erythromycin thiocyanate is also a key intermediate raw material for synthesizing macrolide antibiotics such as erythromycin, roxithromycin, azithromycin, clarithromycin and the like, and has high market value. In recent years, the market demand of erythromycin thiocyanate is increasing, and the annual export amount is also increasing. Erythromycin thiocyanate is a pure fermentation product and cannot be synthesized in large quantities by artificial means in industry. The production of erythromycin thiocyanate by fermentation of strains inevitably generates a large amount of fermentation waste.
Antibiotic dregs are solid wastes involved after antibiotic fermentation in antibiotic manufacturing industry, and are generated in a filtering stage, and a large amount of dregs are generated in both fermentation liquor extraction and hypha extraction modes. The antibiotics produced in China are various in types, generally every 100m3The fermentation liquor can form 30-40 m3The yield of the antibiotic fungi residues in China in 2012 is as high as 130.9 ten thousand tons.
The antibiotic fungi residues mainly contain medicinal components such as mycelium, fermentation metabolic intermediate products, culture medium degradation products, a small amount of antibiotics and the like, the water content of the antibiotic wet fungi residues generated after the antibiotics are fermented is 79-92%, most of the antibiotic wet fungi residues are bound water, the viscosity is high, and the antibiotic wet fungi residues are easy to deteriorate after being placed for a long time. The antibiotic contains rich mycoprotein, crude protein in dry antibiotic dregs accounts for 30-40%, crude fat accounts for 10-20%, organic solvent, calcium, magnesium, trace elements, etc.
Because antibiotic residues and metabolic intermediates exist in the antibiotic residues, the antibiotic residues are special dangerous wastes, and if the antibiotic residues are not properly treated, the antibiotic residues can generate potential harm to the ecological environment and the human health, and the harm has the characteristics of concealment, hysteresis, accumulation, cooperativity, linkage and the like. How to safely and effectively treat antibiotic fungi residues and improve the harmless treatment and resource utilization efficiency becomes a difficult problem to be solved by the emergency basin.
The drying of antibiotic mushroom dregs is a key link for mushroom dregs treatment, because the mushroom dregs directly produced by fermentation have high water content, and the outward transportation treatment needs a large amount of manpower and material resources, so the cost is high. Therefore, at present, production enterprises often perform drying treatment on the mushroom dregs, so that the water content is reduced, the reduction output is realized, the transportation and treatment cost is reduced, and then the resource treatment is performed.
At present, the antibiotic fungi residues are mostly dried by a direct airing method, and are easy to autolyze and deteriorate after being placed for a long time due to high viscosity, high water content and high content of bound water (difficult to dry). The antibiotic bacterium residues can emit strong pungent smell during the airing period, and the bacterium residues have high organic matter content, so that secondary fermentation can be caused, finally, the color becomes black, the stink is generated, and mosquitoes and flies are bred. On the one hand, the malodorous smell can cause serious air pollution; on the other hand, part of antibiotic residues contained in the mushroom dregs can enter soil and enter the ecological system circulation along with the migration and transformation of the soil, so that the generation of drug-resistant microorganisms is accelerated and the drug-resistant microorganisms enter the plant body, and finally the safety of human beings is influenced. In addition, manufacturers adopt heat drying treatment, namely, bacteria residues are dried by using equipment such as spray drying, barrel drying, spiral drying and the like through heat sources such as high-temperature furnace gas, oil lamp heat exchange, steam and the like, but huge energy consumption is generated, and the cost is very high.
Therefore, the method for drying the rhodanamycin residues, which is environment-friendly, saves energy consumption, and has low cost and good drying effect, has very important significance.
Disclosure of Invention
The invention aims to provide a method for drying erythromycin thiocyanate mushroom dregs.
The invention provides a method for drying erythromycin thiocyanate mushroom dregs, which comprises the following steps:
(1) adding water to dilute the erythromycin thiocyanate fungi residues;
(2) adding a flocculating agent to flocculate the fungus residues to obtain a flocculated mixed solution;
(3) feeding the mixed liquid obtained in the step (2) into a plate-and-frame filter press for plate-and-frame filter pressing to obtain filtered fungus residues;
(4) and (4) drying the filtered fungus dregs obtained in the step (3) by hot air through a drier.
Further, the temperature of the erythromycin thiocyanate fungus residue in the step (1) is 20-42 ℃, and the temperature of water is not higher than 35 ℃.
Further, the volume ratio of the erythromycin thiocyanate fungus dregs to the water in the step (1) is 1 (2-7), and preferably 1: 5.
Further, the flocculating agent in the step (2) is polyaluminium chloride and polyacrylamide; preferably, the flocculant is added as follows: respectively adding a polyaluminum chloride aqueous solution and a polyacrylamide aqueous solution; the volume ratio of the mushroom dregs to the polyaluminium chloride aqueous solution and the polyacrylamide aqueous solution is 1 (0.15-0.5) to 0.01-0.1, and the preferred volume ratio is 1:0.22: 0.08; more preferably, the mass percent concentration of the polyaluminum chloride aqueous solution is 10%, and the mass percent concentration of the polyacrylamide aqueous solution is 5% o.
Furthermore, the content of alumina in the polyaluminium chloride is not less than 28%, preferably, the content of alumina in the polyaluminium chloride is 29%; and/or the molecular weight of the polyacrylamide is 15000-25000.
Further, the above-mentioned aqueous solutions of polyaluminum chloride and polyacrylamide are added, respectively, as follows: firstly adding polyaluminium chloride aqueous solution, stirring, then adding polyacrylamide aqueous solution, and stirring.
Furthermore, the stirring speed of adding the polyaluminium chloride aqueous solution for stirring is 800-1000 rad/min, and the stirring time is 20-40 min; preferably, the stirring speed is 900rad/min, and the stirring time is 30 min; and/or the stirring speed of adding the polyacrylamide aqueous solution for stirring is 500-700 rad/min, the stirring time is 50-70 min, preferably the stirring speed is 600rad/min, and the stirring time is 60 min.
Further, the feeding method in the step (3) is as follows: feeding the materials by a low-pressure pump and a high-pressure pump, wherein the pressure of low-pressure feeding is 0.04-0.08 MPa, the time of low-pressure feeding is 16000-20000 s, preferably the pressure is 0.06MPa, and the time of feeding is 18000 s; and/or the pressure of the high-pressure feeding is 0.5-1.5 MPa, the high-pressure feeding time is 8800-12800 s, and preferably the pressure is 1MPa, and the feeding time is 10800 s.
Further, in the step (3), the plate frame filter pressing pressure is 1-1.5 MPa, and the filter pressing time is 1500-2500 s; preferably, the filter pressing pressure of the plate frame is 1.2MPa, and the filter pressing time is 2000 s.
Further, the conditions of the drying machine hot air drying in the step (4) are as follows: drying at 55-75 ℃ for 0.5-1.5 h, preferably at 65 ℃ for 1 h.
The invention also provides dried erythromycin thiocyanate mushroom dregs, which are obtained by drying the erythromycin thiocyanate mushroom dregs by the method.
The method has a very good drying effect, the water content of the dried erythromycin thiocyanate fungus residue is very low and is only 15-22%, high-temperature heat drying is avoided, energy consumption is reduced, waste is avoided, automation of the whole drying process can be realized, manpower is saved, and the cost is greatly reduced. The dried mushroom dregs with low water content are beneficial to further treatment, and the transportation cost and the treatment cost are reduced.
Obviously, many modifications, substitutions, and variations are possible in light of the above teachings of the invention, without departing from the basic technical spirit of the invention, as defined by the following claims.
The present invention will be described in further detail with reference to the following examples. This should not be understood as limiting the scope of the above-described subject matter of the present invention to the following examples. All the technologies realized based on the above contents of the present invention belong to the scope of the present invention.
Detailed Description
The plate-and-frame filter press used in the invention is a product of Shandongjing environmental protection equipment Co., Ltd, and has the following model: XAZCFQ710/2000, the drier is a product of Guangzhou sanden energy equipment, Inc., model number is SBWHD45000, the raw materials and other equipment used in the invention are known products, and the drier is obtained by purchasing a commercial product.
Example 1 method for drying erythromycin thiocyanate mushroom dregs
Step 1, moving to 20m3Adding 100m of erythromycin thiocyanate fungus dregs3Diluting with water;
step 2, adding 4.4m3Aqueous polyaluminum chloride (PAC) solution with concentration of 10%, aluminum oxide (Al) in PAC2O3) The content of (b) is 29%, stirring at 900rad/min for 30min, and adding 3.6m3Polyacrylamide (PAM) aqueous solution with the concentration of 5 per mill is stirred for 60min at the rotating speed of 600 rad/min. At the moment, the fungus residues are flocculated in large scale, and the separation effect of the hypha residues and the water is obvious;
3, pumping the flocculated mixed solution into a plate frame through a low-pressure pump and a high-pressure pump for filter pressing, wherein the pressure of the low-pressure mixed solution entering the plate frame is 0.06MPa, and the low-pressure feeding time is 18000 s; the pressure of high pressure entering the plate frame is 1MPa, and the feeding time is 10800 s. The filter pressing pressure of the plate frame is 1.2MPa, and the filter pressing time is 2000 s.
And 4, drying the filter-pressed solid material with water content of 55-65% in a drier under the following drying conditions: drying at 65 ℃ for 1 h.
As a result: the water content of the erythromycin thiocyanate fungus dreg discharged from the drying machine is detected as follows: 15-22%.
The inventor discovers through screening experiments that:
1. in the flocculation process, factors influencing the flocculation effect are as follows:
(1) volume ratio of mushroom dregs to water, polyaluminium chloride aqueous solution and polyacrylamide aqueous solution
When the volume ratio of the erythromycin thiocyanate slag to water, the polyaluminium chloride aqueous solution (with the concentration of 10%) and the polyacrylamide aqueous solution (with the concentration of 5 ‰) is out of the range of 1 (3-6): (0.2-0.5): 0.06-0.22), the flocculation effect is deteriorated.
(2) Temperature of mushroom dregs and temperature of water for diluting mushroom dregs
When the temperature of the bacterial dregs is not controlled within 20-42 ℃, or the temperature of the primary water exceeds 35 ℃, the flocculation effect is deteriorated.
(3) Time and rate of agitation after addition of flocculant
The longer the stirring time or the higher the rate, the lower the effect of the flocculant; too short a stirring time or too low a speed results in incomplete dissolution of the flocculant, which leads to poor flocculation.
(4) Selection of PAC and PAM
Al of PAC used when flocculating2O3The content of (b) is less than 28%, or the flocculation effect is deteriorated when the molecular weight of PAM is out of the range of 15000 to 25000.
Above-mentioned factor all can show the influence flocculation effect, and wherein arbitrary one leads to the flocculation effect variation, all can further lead to the fungus sediment to be difficult to get into the sheet frame and carry out filter-pressing and subsequent processing, or lead to the filter-pressing effect to reduce, and final drying effect also obviously descends, and the water content that the last erythromycin thiocyanate fungus sediment goes out the desiccator reaches 55 ~ 65%.
2. In the drying process, the drying temperature can obviously influence the drying effect
If the drying is carried out at the temperature higher than 75 ℃, not only can the energy consumption be obviously improved, but also the surface of the material is hardened due to the action of high temperature, but the interior of the material is still moist and cannot be dried, and finally, the drying effect of the erythromycin thiocyanate fungi residue is obviously deteriorated; if the drying temperature is too low, the drying time is significantly prolonged and the drying effect is also reduced. Drying at too high or too low temperature to finally obtain the erythromycin thiocyanate bacterium slag, wherein the water content of the erythromycin thiocyanate bacterium slag discharged from the drying machine reaches 55-65%.
In conclusion, the method has a very good drying effect, the water content of the dried erythromycin thiocyanate fungus residue is very low and is only 15-22%, high-temperature heat drying is avoided, energy consumption is reduced, waste is avoided, automation of the whole drying process can be realized, manpower is saved, and the cost is greatly reduced. The dried mushroom dregs with low water content are beneficial to further treatment, and the transportation cost and the treatment cost are reduced.
Claims (10)
1. A method for drying erythromycin thiocyanate mushroom dregs is characterized by comprising the following steps:
(1) adding water to dilute the erythromycin thiocyanate fungi residues;
(2) adding a flocculating agent to flocculate the fungus residues to obtain a flocculated mixed solution;
(3) feeding the mixed liquid obtained in the step (2) into a plate-and-frame filter press for plate-and-frame filter pressing to obtain filtered fungus residues;
(4) and (4) drying the filtered fungus dregs obtained in the step (3) by hot air through a drier.
2. The method of claim 1, wherein: the temperature of the erythromycin thiocyanate fungus residues in the step (1) is 20-42 ℃, and the temperature of water is not higher than 35 ℃; and/or the volume ratio of the erythromycin thiocyanate fungus dregs to the water is 1 (2-7), and preferably 1: 5.
3. The method of claim 1, wherein: in the step (2), the flocculating agent is polyaluminium chloride and polyacrylamide; preferably, the flocculant is added as follows: respectively adding a polyaluminum chloride aqueous solution and a polyacrylamide aqueous solution; the volume ratio of the mushroom dregs to the polyaluminium chloride aqueous solution and the polyacrylamide aqueous solution is 1 (0.15-0.5) to 0.01-0.1, and the preferred volume ratio is 1:0.22: 0.08; more preferably, the mass percent concentration of the polyaluminum chloride aqueous solution is 10%, and the mass percent concentration of the polyacrylamide aqueous solution is 5% o.
4. The method of claim 3, wherein: the content of alumina in the polyaluminium chloride is not less than 28%, preferably, the content of alumina in the polyaluminium chloride is 29%; and/or the molecular weight of the polyacrylamide is 15000-25000.
5. The method of claim 3, wherein: the step of respectively adding the polyaluminium chloride aqueous solution and the polyacrylamide aqueous solution comprises the following steps: firstly adding polyaluminium chloride aqueous solution, stirring, then adding polyacrylamide aqueous solution, and stirring.
6. The method of claim 5, wherein: the stirring speed of adding the polyaluminium chloride aqueous solution for stirring is 800-1000 rad/min, and the stirring time is 20-40 min; preferably, the stirring speed is 900rad/min, and the stirring time is 30 min; and/or the stirring speed of adding the polyacrylamide aqueous solution for stirring is 500-700 rad/min, the stirring time is 50-70 min, preferably the stirring speed is 600rad/min, and the stirring time is 60 min.
7. The method of claim 1, wherein: the feeding method in the step (3) comprises the following steps: feeding the materials by a low-pressure pump and a high-pressure pump, wherein the pressure of low-pressure feeding is 0.04-0.08 MPa, the time of low-pressure feeding is 16000-20000 s, preferably the pressure is 0.06MPa, and the time of feeding is 18000 s; and/or the pressure of the high-pressure feeding is 0.5-1.5 MPa, the high-pressure feeding time is 8800-12800 s, and preferably the pressure is 1MPa, and the feeding time is 10800 s.
8. The method of claim 1, wherein: in the step (3), the plate frame filter pressing pressure is 1-1.5 MPa, and the filter pressing time is 1500-2500 s; preferably, the filter pressing pressure of the plate frame is 1.2MPa, and the filter pressing time is 2000 s.
9. The method of claim 1, further comprising: the conditions of the drying machine for hot air drying in the step (4) are as follows: drying at 55-75 ℃ for 0.5-1.5 h, preferably at 65 ℃ for 1 h.
10. A dried erythromycin thiocyanate pomace obtained by drying erythromycin thiocyanate pomace by the method according to any one of claims 1 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011638548.0A CN112815638A (en) | 2020-12-31 | 2020-12-31 | Method for drying erythromycin thiocyanate fungus residues |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011638548.0A CN112815638A (en) | 2020-12-31 | 2020-12-31 | Method for drying erythromycin thiocyanate fungus residues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112815638A true CN112815638A (en) | 2021-05-18 |
Family
ID=75857641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011638548.0A Pending CN112815638A (en) | 2020-12-31 | 2020-12-31 | Method for drying erythromycin thiocyanate fungus residues |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112815638A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116239258A (en) * | 2023-03-09 | 2023-06-09 | 河北协同环境科技有限公司 | Advanced treatment process for biological fermentation fungus residues |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1376401A (en) * | 2001-03-27 | 2002-10-30 | 孙玉胜 | Detoxicated pencillim dregs, its preparing process and application of its somatic protein in feed |
| DE10154165A1 (en) * | 2001-11-05 | 2003-05-15 | Hopp Vollrath | Production of filter cakes from liquid manure, useful as soil improvers, fertilizers or fertilizer additives, comprises treatment of coarse solid-free filtrate with a flocculant, followed by pressing of the resultant sediment |
| CN102173443A (en) * | 2011-03-14 | 2011-09-07 | 金泳霖 | Method for preparing gamma-aluminium oxide (Al2O3) framework material by using erythromycin fungus dreg produced by fermentation method as core-shell material |
| CN102212094A (en) * | 2011-03-14 | 2011-10-12 | 金泳霖 | Processing process of erythromycin residual decoction dregs |
| CN105198511A (en) * | 2015-09-18 | 2015-12-30 | 湖北大学 | Multifunctional organic fertilizer prepared by utilizing tannery sludge and wood fibers and preparation method and application thereof |
| CN105733970A (en) * | 2016-02-22 | 2016-07-06 | 伊犁川宁生物技术有限公司 | Harmless treatment method for erythrocin strain residues |
| CN106925593A (en) * | 2015-12-29 | 2017-07-07 | 中国科学院过程工程研究所 | A kind of method of antibiotic fermentation bacteria residue solidification dehydration |
| CN107915763A (en) * | 2016-10-09 | 2018-04-17 | 津药新瑞制药股份有限公司 | A kind of method of neomycin fermented waste fluid slag-liquid separation and recycling residual neomycin |
| CN108101263A (en) * | 2017-12-27 | 2018-06-01 | 宁夏宝塔化工中心实验室(有限公司) | A kind of erythromycin bacterium slag waste water is innoxious with processing equipment for recycling and integrated technique |
| WO2018210379A1 (en) * | 2017-05-15 | 2018-11-22 | Ecoenergy Gesellschaft Für Energie- Und Umwelttechnik Mbh | Method for removing organic and inorganic harmful substances from waste by means of wet mechanical separation |
-
2020
- 2020-12-31 CN CN202011638548.0A patent/CN112815638A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1376401A (en) * | 2001-03-27 | 2002-10-30 | 孙玉胜 | Detoxicated pencillim dregs, its preparing process and application of its somatic protein in feed |
| DE10154165A1 (en) * | 2001-11-05 | 2003-05-15 | Hopp Vollrath | Production of filter cakes from liquid manure, useful as soil improvers, fertilizers or fertilizer additives, comprises treatment of coarse solid-free filtrate with a flocculant, followed by pressing of the resultant sediment |
| CN102173443A (en) * | 2011-03-14 | 2011-09-07 | 金泳霖 | Method for preparing gamma-aluminium oxide (Al2O3) framework material by using erythromycin fungus dreg produced by fermentation method as core-shell material |
| CN102212094A (en) * | 2011-03-14 | 2011-10-12 | 金泳霖 | Processing process of erythromycin residual decoction dregs |
| CN105198511A (en) * | 2015-09-18 | 2015-12-30 | 湖北大学 | Multifunctional organic fertilizer prepared by utilizing tannery sludge and wood fibers and preparation method and application thereof |
| CN106925593A (en) * | 2015-12-29 | 2017-07-07 | 中国科学院过程工程研究所 | A kind of method of antibiotic fermentation bacteria residue solidification dehydration |
| CN105733970A (en) * | 2016-02-22 | 2016-07-06 | 伊犁川宁生物技术有限公司 | Harmless treatment method for erythrocin strain residues |
| CN107915763A (en) * | 2016-10-09 | 2018-04-17 | 津药新瑞制药股份有限公司 | A kind of method of neomycin fermented waste fluid slag-liquid separation and recycling residual neomycin |
| WO2018210379A1 (en) * | 2017-05-15 | 2018-11-22 | Ecoenergy Gesellschaft Für Energie- Und Umwelttechnik Mbh | Method for removing organic and inorganic harmful substances from waste by means of wet mechanical separation |
| CN108101263A (en) * | 2017-12-27 | 2018-06-01 | 宁夏宝塔化工中心实验室(有限公司) | A kind of erythromycin bacterium slag waste water is innoxious with processing equipment for recycling and integrated technique |
Non-Patent Citations (2)
| Title |
|---|
| 环境保护部污染防治司: "《国家环境友好企业创建工作手册》", 30 September 2009, 中国环境科学出版社, pages: 334 - 335 * |
| 马忠青、李鹏伟、韩星杰: "低温干化技术在抗生素菌渣处理上的应用", 《中国环境科学学会2019年科学技术年会——环境工程技术创新与应用分论坛论文集（三）》, 23 August 2019 (2019-08-23), pages 549 - 552 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116239258A (en) * | 2023-03-09 | 2023-06-09 | 河北协同环境科技有限公司 | Advanced treatment process for biological fermentation fungus residues |
| CN116239258B (en) * | 2023-03-09 | 2023-12-15 | 河北协同环境科技有限公司 | Advanced treatment process for biological fermentation fungus residues |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102992553B (en) | Method for comprehensively treating and utilizing dissolving pulp black liquor | |
| CN100551933C (en) | A kind of method of extracting bacteria alginate | |
| CN102583684B (en) | Method for preparing flocculating agent from paper mill sludge | |
| CN107827335B (en) | Municipal sludge harmless treatment method | |
| CN103159513A (en) | Method for producing biological bactericide by using paper-making wastewater | |
| KR101123854B1 (en) | Wet-dry serial parallel anaerobic digestion apparatus and method for treating organic waste | |
| CN112815638A (en) | Method for drying erythromycin thiocyanate fungus residues | |
| CN105016600A (en) | Sludge biological drying method | |
| CN104445851A (en) | Method for recycling sludge processing waste liquid to promote sludge harmless treatment | |
| CN106348562A (en) | Method for treating active sludge generated by sewage treatment and extracting protein | |
| CN107244781A (en) | A kind of processing method of paper waste | |
| CN103910476B (en) | Based on the municipal dewatered sludge of NaOH pretreatment without the biological dewatered method of auxiliary material | |
| CN106929539B (en) | Method for improving biogas yield through combined digestion of cow dung and pretreated corn straws | |
| CN108424215A (en) | A kind of method of sludge and garden garbage efficient low-consume aerobic compost | |
| CN101712503B (en) | Processing method of printing and dyeing textile sewage | |
| CN110759754A (en) | Harmless treatment and resource utilization method of glucosamine fermentation bacterium residues | |
| CN115650541A (en) | Heavy metal sludge treatment method | |
| CN105347875A (en) | Rapid odorless composting method for fresh filter mud in cane sugar factory and treatment system | |
| CN211814058U (en) | Sludge resource treatment device | |
| CN111320332B (en) | Leather sewage emission reduction treatment method | |
| CN113548786A (en) | Novel sludge dehydrating agent and using method thereof | |
| CN112726284A (en) | Composite paper and preparation method thereof | |
| CN111777151A (en) | Quaternary composite flocculant | |
| CN116354750A (en) | Treatment method of erythromycin thiocyanate fungus residues | |
| CN110746061A (en) | Sludge treatment method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210518 |
|
| RJ01 | Rejection of invention patent application after publication |