CN112812950A - Biological cell lysis preparation workstation - Google Patents

Biological cell lysis preparation workstation Download PDF

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Publication number
CN112812950A
CN112812950A CN202110096151.1A CN202110096151A CN112812950A CN 112812950 A CN112812950 A CN 112812950A CN 202110096151 A CN202110096151 A CN 202110096151A CN 112812950 A CN112812950 A CN 112812950A
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liquid
shaking
transmission
vertical
horizontal
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CN202110096151.1A
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吴永芝
刘义生
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Suzhou Baofangu Industrial Technology Co ltd
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Suzhou Baofangu Industrial Technology Co ltd
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Priority to CN202110096151.1A priority Critical patent/CN112812950A/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/08Flask, bottle or test tube
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/10Rotating vessel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16Vibrating; Shaking; Tilting

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  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a biological cell cracking preparation workstation which comprises a box body assembly, a feeding and discharging device, a horizontal liquid shaking device, a vertical liquid shaking device and a power transmission device, wherein the feeding and discharging device is fixedly connected with the box body assembly, the box body assembly comprises a mounting plate, the horizontal liquid shaking device is mounted on one side of the upper end of the mounting plate, the vertical liquid shaking device is mounted on one side, far away from the horizontal liquid shaking device, of the upper end of the mounting plate, the power transmission device is fixedly connected with the mounting plate, the bottom end of a liquid removing mechanical arm is fixedly connected with the mounting plate, a plurality of liquid injection mechanical arms are arranged on the mounting plate, the liquid injection mechanical arms are fixedly connected with the mounting plate, a plurality of screwing mechanical arms are arranged on one.

Description

Biological cell lysis preparation workstation
Technical Field
The invention relates to the technical field of biological cell lysis, in particular to a biological cell lysis preparation workstation.
Background
At present, the biological cell lysis is mostly prepared by manual work in the market, especially in the laboratory, but when mass production is needed, a large amount of manpower is often needed for participation, the working efficiency is low, the configuration deviation of the culture solution can be caused due to the difference of individual levels, the final experimental result is influenced, in addition, in order to simulate the special living environment of fungi, some special substances are often added into the culture solution, and the special substances are directly exposed in the air and can cause harm to the health of human bodies, and the isolation through wearing protective clothing is not beneficial to the experimental operation, and an independent closed laboratory is needed for preventing leakage, so that the experimental cost is increased, especially when mass preparation is carried out, a large amount of personnel participation is needed for improving the efficiency, the space is narrow, the operation is not beneficial to expansion, in addition, because the density difference of some culture solutions is too large, simple filling can lead to the culture solution layering, is unfavorable for later stage schizolysis to generate, carries out artifical mixture during large-scale experiment and increases the configuration degree of difficulty.
Disclosure of Invention
The present invention is directed to a biological cell lysis preparation workstation, which solves the above problems of the prior art.
In order to solve the technical problems, the invention provides the following technical scheme:
the utility model provides a biological cell schizolysis preparation workstation, includes box subassembly, go up unloader, level and shakes liquid device, vertical liquid device and power transmission unit that shakes, goes up unloader and box subassembly fastening connection, and the box subassembly includes the mounting panel, and the level shakes liquid device and installs in mounting panel upper end one side, and vertical liquid device that shakes is installed and is kept away from horizontal liquid device one side in the mounting panel upper end, and power transmission unit and mounting panel fastening connection.
The invention carries out mechanical batch configuration on the target bottle for biological cell lysis to replace manual configuration, ensures the processing efficiency and reduces the labor cost, the target bottle is automatically fed by the feeding and discharging device, the mounting plate is a main mounting substrate, the device controls the processing process by the controller, the precision is higher, the configuration process weakens the vibration influence, the single injection amount of the culture solution is less, the culture solution injected into the target bottle in times is easy to stratify due to higher density, in order to ensure that the culture solution in the target bottle is uniformly mixed, a horizontal shaking device and a vertical shaking device are additionally arranged on the upper surface of the mounting plate, the horizontal shaking device picks up the target bottle by the chuck and rotates on the horizontal plane to mix the culture solution injected in times, in order to ensure that the target bottle cannot fall off from the chuck, the controller controls the target bottle to rotate at a lower rotating speed, the lower meeting of rotational speed leads to the culture solution to mix inadequately, consequently changes over to next station after mixing and reinjects into the culture solution, then rocks in vertical plane rotating the target bottle through vertical rocking liquid device, rotates through horizontal plane and vertical face in turn, makes the culture solution further mix, and power transmission device and mounting panel fastening connection guarantee that the torque transmission is steady.
Furthermore, the box body assembly further comprises an upper frame, a lower frame and an alarm lamp, one side of the upper frame is connected with the mounting plate in a sealing mode, one side of the lower frame is fixedly connected with one side, far away from the upper frame, of the mounting plate, and the alarm lamp is mounted at the upper end of the upper frame.
In order to provide an ideal experimental space for the preparation of biological cell lysis, constitute a confined space between last frame and mounting panel, be main working space, the target bottle keeps sealed when entering into tooling device, and only can carry out the opening and annotate the liquid in the device, influence the experiment result in preventing that external foreign matter from falling into the target bottle, the mounting panel is main bearing plate, cause positioning deviation in order to prevent collision and vibrations, frame and mounting panel fastening connection will descend, for the ease of detecting special plane behavior, set up the warning light at the top when equipment trouble or operation are incorrect, the warning light scintillation.
Further, the feeding and discharging device comprises a feeding assembly, a transmission assembly and a wire protecting chain, a plurality of safety baffles are arranged at the upper end of the feeding assembly, the feeding assembly is fixedly connected with a mounting plate, the transmission assembly is fixedly connected with one side of the wire protecting chain, the feeding assembly comprises a feeding cylinder, a feeding pile, a transmission block and a pile support, one side of the feeding cylinder is fixedly connected with the pile support, the output end of the feeding cylinder is fixedly connected with the transmission block, feeding guide rails are arranged at two sides of the bottom end of the feeding pile, a sliding block is arranged at the top end of the pile support, the sliding block of the pile support is slidably connected with the feeding guide rails, the middle of the bottom end of the feeding pile is fixedly connected with the transmission block, the transmission assembly is fixedly connected with the mounting plate, the transmission assembly comprises a sliding cylinder, a lead screw, a nut, a bearing seat, a transmission support, a transmission chuck, a chuck, the output end of the sliding cylinder is fixedly connected with one side of the screw rod, two ends of the screw rod are movably connected with the bearing seat, one end of the transmission support is provided with an installation cavity, the inner wall surface of the installation cavity of the bearing seat is fixedly connected with the inner wall surface of the transmission support, the nut is connected with the screw rod in a threaded manner, the outer circular surface of the nut is fixedly connected with one side of the transmission slide block, one side of the transmission support is fixedly connected with a protection wire chain, the bottom end of the transmission support is fixedly connected with the installation plate, one side of the transmission support is provided with a transmission guide rail, the transmission slide block is slidably connected with the transmission guide rail, one side of the transmission slide block is provided with a guide rail, the direction of the transmission slide block guide rail is perpendicular to that of the transmission guide rail, one.
The periphery of the feeding assembly is provided with safety baffles to prevent target bottles from tilting during transfer installation, the feeding assembly is fixedly connected with the installation plate, the influence of working vibration of a feeding cylinder on feeding is reduced, a power line and a control line are uniformly fixed through a wire protection chain, the wire protection chain is tied at one end of a transmission bracket in order to prevent a line from interfering movement, the wire protection chain is freely stretched along with movement of a nut, in order to improve infusion efficiency of culture solution, a plurality of target bottles are neatly placed on feeding stacking, the target bottles are automatically picked up through a transmission chuck, one side of the feeding cylinder is fixedly connected with a stacking bracket, the feeding cylinder is installed and positioned, the output end of the feeding cylinder is fixedly connected with a transmission block, the transmission block is controlled to reciprocate through cylinder movement, the middle of the bottom end of the feeding cylinder is fixedly connected with the transmission block, and a guide rail and a sliding block are additionally arranged for accurately controlling feeding stacking movement, the feeding stacking movement is guided through sliding connection, the feeding stacking movement is finished along with the completion of filling and sealing of target bottles close to one side of a transmission chuck, the feeding stacking movement is controlled through an air cylinder to move to one side of the transmission chuck, an alarm lamp is lightened and then replaced after all the target bottles are infused, the feeding stacking movement is controlled through a sliding air cylinder, the transmission chuck is controlled to move horizontally, the sliding air cylinder is installed on one side of a transmission support for facilitating and driving, an output end is tightly connected with a lead screw, positioning control is more accurate through threaded engagement, the adjustment times of the transmission chuck are reduced, two bearing blocks are installed in a transmission support installation cavity, the lead screw can rotate along an axis through movable connection of a built-in bearing and two ends of the lead screw, the transmission slide block tightly connected with a nut is controlled to move on the horizontal plane, when the feeding stacking movement is moved to the position right above the target bottles, a chuck fixing plate is controlled to move along the The target bottle then shifts up transmission cylinder control chuck to send into next station through slip cylinder control target bottle horizontal migration, can pick up the target bottle of co-altitude through vertical removal, the practicality is higher, through fastening connection between each part, makes controller control accuracy higher, and machining efficiency also further improves.
Further, the horizontal shaking liquid device comprises a horizontal shaking liquid bracket, a horizontal shaking liquid beam, a horizontal shaking liquid slider, a horizontal shaking liquid cylinder, a horizontal rotary table, a first motor, a first guide post and a first slider, wherein the top end of the horizontal shaking liquid bracket is fixedly connected with one side of the horizontal shaking liquid beam, the bottom end of the horizontal shaking liquid bracket is fixedly connected with a mounting plate, one side of the horizontal shaking liquid beam is provided with a horizontal shaking liquid guide rail, the horizontal shaking liquid slider is in sliding connection with the horizontal shaking liquid guide rail, the top end of the horizontal shaking liquid slider is fixedly connected with the horizontal shaking liquid cylinder, one side of the horizontal shaking liquid slider is provided with a vertical guide rail vertical to the horizontal shaking liquid guide rail, one side of the first motor is provided with a slider, the first motor slider is in sliding connection with the horizontal shaking liquid slider vertical guide rail, the output end of the horizontal shaking liquid cylinder is fixedly connected with the first motor slider, the output end of the first motor is fixedly connected with the horizontal rotary table, and the, horizontal rocking liquid crossbeam one side is equipped with guide post mounting groove, and first guide post and horizontal rocking liquid crossbeam guide post mounting groove terminal surface fastening connection, first slider and first guide post sliding connection, first guide post one side and horizontal rocking liquid slider fastening connection are kept away from to first slider.
The horizontal shaking liquid device is arranged on one side of the mounting plate, in order to facilitate the picking of target bottles, two groups of guide rail sliding block mechanisms are arranged on the horizontal shaking liquid device, the motion is guided, in order to prevent the horizontal shaking liquid from colliding with other parts, the target bottles are moved along the direction far away from the screwing manipulator along the horizontal direction through the horizontally arranged guide rail sliding block mechanisms, the target bottles with different heights are picked up through the vertically arranged guide rail sliding block mechanisms, because the linear displacement of the horizontal shaking liquid chuck is controlled through a cylinder, the influence of vibration on the displacement is reduced through fastening connection, a guide rail is arranged on the horizontal shaking liquid slider in order to improve the integration performance of the horizontal shaking liquid device, a sliding block is arranged on one side of a first motor, the output end of the horizontal shaking liquid cylinder is fastened and connected with the sliding block of the first motor, the up and down movement of the first motor is precisely controlled, and the output end of, rotate horizontal carousel through first motor and rotate control along the axle center and rotate, make the culture solution in the target bottle mix gradually through rotating, be equipped with a plurality of horizontal shaking liquid chucks at horizontal carousel lower surface, can control a plurality of target bottles and rotate, improve work efficiency, control horizontal shaking liquid chuck through small-size cylinder and press from both sides tight target bottle bottleneck, small-size cylinder of every horizontal shaking liquid chuck configuration, carry out the independent control to horizontal shaking liquid chuck, add a guide post slider mechanism on horizontal shaking liquid crossbeam, with the cooperation of guide rail slider mechanism, carry out two-way location to horizontal migration, make the displacement precision higher.
Further, the vertical liquid shaking device comprises a vertical liquid shaking support, a vertical liquid shaking crossbeam, a vertical liquid shaking slide block, a vertical liquid shaking cylinder, a vertical rotary table, a second motor, a second guide post and a second slide block, wherein the top end of the vertical liquid shaking support is fixedly connected with one side of the vertical liquid shaking crossbeam, the bottom end of the vertical liquid shaking support is fixedly connected with the mounting plate, one side of the vertical liquid shaking crossbeam is provided with a vertical liquid shaking guide rail, the vertical liquid shaking slide block is slidably connected with the vertical liquid shaking guide rail, one side of the vertical liquid shaking slide block is fixedly connected with the vertical liquid shaking cylinder, one side of the vertical liquid shaking slide block is provided with a vertical guide rail perpendicular to the vertical liquid shaking guide rail, one side of the second motor is provided with a slide block, the second motor slide block is slidably connected with the vertical liquid shaking slide rail of the vertical liquid shaking slide block, the output end of the vertical liquid shaking cylinder is fixedly connected with the second motor slide block, the output end, vertical liquid crossbeam one side of shaking is equipped with the guide post mounting groove, and second guide post and vertical liquid crossbeam guide post mounting groove terminal surface fastening connection shake, first slider and second guide post sliding connection, second guide post one side and vertical liquid slider fastening connection shake are kept away from to the second slider.
The target bottle after horizontal shaking is sent to the screwing manipulator, the screwing manipulator unscrews the target bottle cap, culture solution is injected into the target bottle again through the liquid injection manipulator along with the rotation of the rotating disc, the bottle cap is screwed down through the screwing manipulator after the liquid injection again, the horizontal shaking cannot enable the culture solution to be mixed more uniformly along with the increase of components of the culture solution, the culture solution is further mixed through the vertical shaking device, the culture solution is not layered for two times, the vertical shaking support, the vertical shaking beam and the mounting plate are connected more tightly through fastening connection, the positioning error caused by external collision is weakened, the vertical shaking guide rail is arranged on one side of the vertical beam, the horizontal displacement is guided through sliding connection with the vertical shaking slide block, bidirectional positioning is realized through the guide column slide block mechanism, the positioning precision is improved, and one side of the vertical shaking cylinder is fastened and connected with the vertical shaking slide block, the vertical displacement mechanism moves horizontally along with the movement of the sliding block, then the second motor moves along the vertical direction through a vertical liquid shaking guide rail arranged on a vertical liquid shaking sliding block, along with the downward movement of the second motor, a plurality of vertical liquid shaking chucks arranged on a vertical rotary disc touch a target bottle mouth, the vertical liquid shaking chucks are controlled by a small-sized cylinder to clamp the bottle mouth of the target bottle, in order to prevent the target bottle from colliding with other devices when the vertical rotary disc rotates, the height of the chucks is lifted through a vertically arranged guide rail sliding block mechanism, the vertical rotary disc is far away from a screwing manipulator through a horizontally arranged guide rail sliding block mechanism, the second motor drives the vertical rotary disc to rotate along the axis, the target bottle rotates along with the chuck, culture solution in the target bottle is overturned and mixed on the vertical plane, the mixing degree of the culture solution in the target bottle is further improved, the total number of two vertical liquid shaking devices is two, and the target, the waiting time that the target bottle was got to vertical liquid chuck clamp has been shortened, sets up a plurality of vertical liquid chucks of shaking under the vertical carousel and can constantly pick up the target bottle along with the carousel rotates, then through second motor drive, shakes the liquid to a plurality of target bottles simultaneously, improves the efficiency of shaking the liquid greatly.
Further, power transmission device includes driving motor, reduction gear, flange carousel, rolling disc, reduction gear support and supplementary runner assembly, and driving motor one side and reduction gear rotate to be connected, reduction gear and reduction gear support fastening connection, and the reduction gear support upwards extends and is equipped with the support column, reduction gear support column and mounting panel fastening connection, reduction gear and flange carousel fastening connection, flange carousel bottom and rolling disc fastening connection, and the rolling disc lower surface is equipped with a plurality of supplementary runner assemblies, supplementary runner assembly includes runner and runner support, runner and runner support swing joint.
The invention takes the driving motor as the main power source of the power transmission device, in order to improve the stability among all parts, the influence of vibration on torque transmission is reduced by fastening connection, the output torque of the driving motor is directly connected to the rotating disc, because the rotating speed of the driving motor is too high, force transmission is unstable and inconvenient to rotate, the output rotating speed is reduced by the reducer, and the reduced torque is transmitted to the rotating disc by the flange rotating disc, the torque output is more stable because the contact surface between the flange rotating disc and the rotating disc is larger, in order to reduce the radial force to the output shaft of the reducer when the rotating disc rotates, a plurality of auxiliary rotating assemblies are arranged at the bottom end of the rotating disc along the circumferential direction, the auxiliary rotating assemblies are arranged on the rotating disc by the rotating wheel bracket, the rotating wheel rolls on the surface of the mounting plate along with the rotation of the rotating disc, and plays a, further improving the stability of the rotation of the rotating disc.
Further, the preparation workstation still includes removes liquid manipulator, removes liquid manipulator bottom and mounting panel fastening connection, is equipped with a plurality of notes liquid manipulators on the mounting panel, annotates liquid manipulator and mounting panel fastening connection, and rolling disc one side is equipped with a plurality of screwing manipulators along the circumferencial direction, screwing manipulator bottom and rolling disc fastening connection.
After a target bottle is sent to a screwing manipulator for uncapping, the target bottle is clamped out through a liquid removing manipulator, the target bottle is inverted, residual liquid in the target bottle after cleaning is removed, residual liquid is collected through a connecting disc at the bottom end of the liquid removing manipulator, multi-component culture solution can be prepared through a plurality of arranged liquid injection manipulators, each manipulator controls an air cylinder to work through a controller, vibration is large, the work is smoother through fastening connection, a plurality of screwing manipulators are arranged on a rotating disc in order to improve the work efficiency, each station corresponds to at least one screwing manipulator, the transmission path between adjacent stations is reduced, the liquid injection efficiency is improved, the screwing manipulators have the function of code spraying on the target bottle besides the cap screwing operation, the target bottle is convenient to distinguish, particularly when the large-batch culture solution is prepared, the classification efficiency is greatly improved.
Compared with the prior art, the invention has the following beneficial effects: according to the invention, the target bottles for biological cell lysis are mechanically configured in batches to replace manual configuration, so that the processing efficiency is ensured, the labor cost is reduced, and the target bottles are automatically fed through the feeding and discharging device; a horizontal liquid shaking device and a vertical liquid shaking device are additionally arranged on the upper surface of the mounting plate, and culture solution is uniformly mixed through the alternate rotation of a horizontal plane and a vertical plane; a closed space is formed between the upper frame and the mounting plate, the target bottle keeps sealed when entering the tool device, and only the device is opened for liquid injection, so that external foreign matters are prevented from falling into the target bottle to influence an experimental result; two groups of guide rail sliding block mechanisms are arranged on the horizontal liquid shaking device, the target bottles are enabled to move along the direction away from the screwing manipulator along the horizontal direction through the horizontally arranged guide rail sliding block mechanisms, other parts are not collided during horizontal liquid shaking, and the target bottles with different heights are picked up through the vertically arranged guide rail sliding block mechanisms; the auxiliary rotating assemblies are arranged at the bottom end of the rotating disc along the circumferential direction, and the rotating wheel rolls on the surface of the mounting plate along with the rotation of the rotating disc, so that the rotating disc is supported, and the rotating stability of the rotating disc is further improved; the screwing manipulator has the function of spraying codes to the target bottles besides the operation of screwing the cover, is convenient to distinguish the target bottles, and greatly improves the classification efficiency especially when large-batch culture solution is prepared.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is a schematic diagram of the operational configuration of the present invention;
FIG. 2 is a schematic structural view of the case assembly of the present invention;
FIG. 3 is a schematic structural view of a loading and unloading apparatus according to the present invention;
FIG. 4 is a left side view of the view of FIG. 3;
FIG. 5 is a schematic view of the structure of a horizontal shaking device;
FIG. 6 is a top view of the view of FIG. 5;
FIG. 7 is a schematic view of the vertical shaking device;
FIG. 8 is a left side view of the view of FIG. 7;
FIG. 9 is a top view of the view of FIG. 7;
FIG. 10 is a schematic structural view of the power transmission device of the present invention;
FIG. 11 is a general installation configuration of the present invention
In the figure: 1-box body component, 11-upper rack, 12-lower rack, 13-mounting plate, 14-alarm lamp, 2-loading and unloading device, 21-loading component, 211-loading cylinder, 212-loading and stacking, 213-transmission block, 214-stacking bracket, 215-loading guide rail, 22-transmission component, 221-sliding cylinder, 222-lead screw, 223-nut, 224-bearing seat, 225-transmission bracket, 2251-transmission guide rail, 226-transmission chuck, 227-chuck fixing plate, 228-transmission cylinder, 229-transmission slider, 23-safety baffle, 24-wire protection chain, 3-liquid removing manipulator, 4-horizontal shaking device, 41-horizontal shaking device bracket, 42-horizontal shaking device beam, 421-horizontal shaking liquid guide rail, 43-horizontal shaking liquid slide block, 44-horizontal shaking liquid cylinder, 45-horizontal rotary table, 46-first motor, 47-horizontal shaking liquid chuck, 48-first guide column, 49-first slide block, 5-vertical shaking liquid device, 51-vertical shaking liquid bracket, 52-vertical shaking liquid beam, 521-vertical shaking liquid guide rail, 53-vertical shaking liquid slide block, 54-vertical shaking liquid cylinder, 55-vertical rotary table, 56-second motor, 57-vertical shaking liquid chuck, 58-second guide column, 59-second slide block, 6-rotary-joint mechanical arm, 7-power transmission device, 71-driving motor, 72-speed reducer, 73-flange rotary table, 74-rotary table, 75-speed reducer bracket, 76-auxiliary rotating assembly, 761-rotating wheel, 762-rotating wheel support and 8-liquid injection manipulator.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides the technical scheme that:
as shown in figures 1 and 11, the biological cell lysis preparation workstation comprises a box body assembly 1, a feeding and discharging device 2, a horizontal liquid shaking device 4, a vertical liquid shaking device 5 and a power transmission device 7, wherein the feeding and discharging device 2 is fixedly connected with the box body assembly 1, the box body assembly 1 comprises a mounting plate 13, the horizontal liquid shaking device 4 is mounted on one side of the upper end of the mounting plate 13, the vertical liquid shaking device 5 is mounted on one side, far away from the horizontal liquid shaking device 4, of the upper end of the mounting plate 13, and the power transmission device 7 is fixedly connected with the mounting plate 13.
The invention carries out mechanical batch configuration on the target bottles for preparing the biological cells by cracking, replaces manual configuration, ensures the processing efficiency and reduces the labor cost, the target bottles are automatically fed by the feeding and discharging device 2, the mounting plate 13 is a main mounting base plate, the device controls the processing process by the controller, the precision is higher, the configuration process weakens the vibration influence, the single injection amount of the culture solution is less, the culture solution injected into the target bottles in times is easy to stratify due to higher density, in order to uniformly mix the culture solution in the target bottles, the horizontal shaking device 4 and the vertical shaking device 5 are additionally arranged on the upper surface of the mounting plate 13, the horizontal shaking device 4 picks up the target bottles by the chucks and rotates on the horizontal plane to mix the culture solution injected in times, in order to ensure that the target bottles cannot fall off from the chucks, the controller controls the target bottles to rotate at a lower rotating speed, the lower meeting of rotational speed can lead to the culture solution to mix inadequately, consequently changes to next station after mixing and reinjects into the culture solution, then rocks in vertical plane rotating the target bottle through vertical liquid device 5, rotates through horizontal plane and vertical face in turn, makes the culture solution further mix, and power transmission device 7 and mounting panel 13 fastening connection guarantee that the torque transmission is steady.
As shown in FIG. 2, the box assembly 1 further comprises an upper frame 11, a lower frame 12 and an alarm lamp 14, wherein one side of the upper frame 11 is hermetically connected with a mounting plate 13, one side of the lower frame 12 is fixedly connected with one side of the mounting plate 13 far away from the upper frame 11, and the alarm lamp 14 is mounted at the upper end of the upper frame 11.
In order to provide an ideal experimental space for the preparation of biological cell lysis, a closed space is formed between the upper frame 11 and the mounting plate 13 and is a main working space, a target bottle keeps sealed when entering a tooling device, and only opening liquid injection can be carried out in the device to prevent external foreign matters from falling into the target bottle to influence an experimental result, the mounting plate 13 is a main bearing plate, in order to prevent collision and vibration from causing positioning deviation, the lower frame 12 and the mounting plate 13 are fixedly connected, in order to detect the working condition of a special machine, the alarm lamp 14 is arranged at the top, and when equipment fails or is not operated correctly, the alarm lamp 14 flickers.
As shown in fig. 1 to 4, the loading and unloading device 2 includes a loading assembly 21, a transmission assembly 22 and a wire protecting chain 24, the upper end of the loading assembly 21 is provided with a plurality of safety baffles 23, the loading assembly 21 is fastened with a mounting plate 13, the transmission assembly 22 is fastened with one side of the wire protecting chain 24, the loading assembly 21 includes a loading cylinder 211, a loading pallet 212, a transmission block 213 and a pallet support 214, one side of the loading cylinder 211 is fastened with the pallet support 214, the output end of the loading cylinder 211 is fastened with the transmission block 213, two sides of the bottom end of the loading pallet 212 are provided with loading guide rails 215, the top end of the pallet support 214 is provided with a slide block, the pallet support 214 slide block is slidably connected with the loading guide rails 215, the middle of the bottom end of the loading pallet 212 is fastened with the transmission block 213, the transmission assembly 22 is fastened with the mounting plate 13, the transmission assembly 22 includes a sliding cylinder 221, a lead screw 222, the transmission device comprises a transmission bracket 225, a transmission chuck 226, a chuck fixing plate 227, a transmission cylinder 228 and a transmission slide block 229, wherein one side of the sliding cylinder 221 is tightly connected with the transmission bracket 225, the output end of the sliding cylinder 221 is tightly connected with one side of a lead screw 222, two ends of the lead screw 222 are movably connected with a bearing seat 224, one end of the transmission bracket 225 is provided with a mounting cavity, the bearing seat 224 is tightly connected with the inner wall surface of the mounting cavity of the transmission bracket 225, a nut 223 is in threaded connection with the lead screw 222, the outer circular surface of the nut 223 is tightly connected with one side of the transmission slide block 229, one side of the transmission bracket 225 is tightly connected with a wire protecting chain 24, the bottom end of the transmission bracket 225 is tightly connected with a mounting plate 13, one side of the transmission bracket 225 is provided with a transmission guide rail 2251, the transmission slide block 229 is in sliding connection with the transmission guide rail 2251, one, one side of the transmission cylinder 228 is tightly coupled to the transmission slider 229, the output side of the transmission cylinder 228 is tightly coupled to the collet fixing plate 227, and the collet fixing plate 227 is tightly coupled to the transmission collet 226.
The periphery of the feeding assembly 21 is provided with the safety baffle 23 to prevent the target bottles from tilting during transferring and installation, the feeding assembly 21 is fixedly connected with the installation plate 13, the influence of the working vibration of the feeding cylinder 211 on feeding is reduced, the power line and the control line are uniformly fixed through the wire protection chain 24, in order to prevent the line from interfering movement, the wire protection chain 24 is confined at one end of the transmission bracket 225, the wire protection chain 24 freely stretches along with the movement of the nut 223, in order to improve the culture solution infusion efficiency, a plurality of target bottles are orderly placed on the feeding stacking 212, the target bottles are automatically picked up through the transmission chuck 226, one side of the feeding cylinder 211 is fixedly connected with the stacking bracket 214, the feeding cylinder 211 is installed and positioned, the output end of the feeding cylinder 211 is fixedly connected with the transmission block 213, the reciprocating movement of the transmission block 213 is controlled through the cylinder movement, and the middle of the bottom end of the feeding stacking 212 is fixedly connected with the, in order to accurately control the movement of the feeding pallet 212, a guide rail and a slide block are additionally arranged, the movement of the feeding pallet 212 is guided through sliding connection, along with the completion of filling and sealing of target bottles close to one side of a transmission chuck 226, the feeding pallet 212 is controlled to move to one side of the transmission chuck 226 through an air cylinder until alarm lamps 14 are lightened and then replaced after infusion of all the target bottles is completed, as a plurality of target bottles are arranged on the feeding pallet 212 in a longitudinal and transverse mode, the transmission chuck 226 is controlled to move in the horizontal direction through a sliding air cylinder 221, the sliding air cylinder 221 is installed on one side of a transmission bracket 225 for transmission, the output end is tightly connected with a lead screw 222, positioning control is more accurate through threaded engagement, the adjustment times of the transmission chuck 226 are reduced, two bearing blocks 224 are installed in an installation cavity of the transmission bracket 225, and the lead screw 222 can rotate along the axial line through the, and control and fasten the transmission slide block 229 that connects with nut 223 and move on the horizontal plane, when moving to the goal bottle directly over, through the vertical direction movement of transmission cylinder 228 control chuck fixed plate 227 and touch the goal bottleneck and grasp the goal bottle, then the transmission cylinder 228 control chuck shifts up, and through sliding cylinder 221 control goal bottle horizontal migration send next station into, can pick up the goal bottle of different heights through vertical movement, the practicality is higher, through the fastening connection between each part, make the control accuracy of the controller higher, the machining efficiency also further improves.
As shown in fig. 5 to 6, the horizontal shaking liquid device 4 comprises a horizontal shaking liquid bracket 41, a horizontal shaking liquid beam 42, a horizontal shaking liquid slider 43, a horizontal shaking liquid cylinder 44, a horizontal rotary table 45, a first motor 46, a first guide column 48 and a first slider 49, wherein the top end of the horizontal shaking liquid bracket 41 is fastened and connected with one side of the horizontal shaking liquid beam 42, the bottom end of the horizontal shaking liquid bracket 41 is fastened and connected with the mounting plate 13, one side of the horizontal shaking liquid beam 42 is provided with a horizontal shaking liquid guide rail 421, the horizontal shaking liquid slider 43 is connected with the horizontal shaking liquid guide rail 421 in a sliding manner, the top end of the horizontal shaking liquid slider 43 is fastened and connected with the horizontal shaking liquid cylinder 44, one side of the horizontal shaking liquid slider 43 is provided with a vertical guide rail perpendicular to the horizontal shaking liquid guide rail 421, one side of the first motor 46 is provided with a slider, the slider of the first motor 46 is connected with the vertical guide rail in a sliding manner, the output end of the horizontal shaking liquid cylinder, the output end of the first motor 46 is fixedly connected with the horizontal rotary table 45, a plurality of horizontal shaking liquid chucks 47 are arranged on the bottom surface of the horizontal rotary table 45, a guide post mounting groove is formed in one side of the horizontal shaking liquid beam 42, a first guide post 48 is fixedly connected with the end face of the guide post mounting groove of the horizontal shaking liquid beam 42, a first sliding block 49 is slidably connected with the first guide post 48, and the first sliding block 49 is far away from one side of the first guide post 48 and is fixedly connected with the horizontal shaking liquid sliding block 43.
The horizontal shaking liquid device 4 is arranged on one side of the mounting plate 13, in order to pick up a target bottle conveniently, two groups of guide rail sliding block mechanisms are arranged on the horizontal shaking liquid device 4, the motion is guided, in order to prevent the horizontal shaking liquid from colliding with other parts, the target bottle is moved along the direction far away from the screwing manipulator 6 along the horizontal direction through the horizontally arranged guide rail sliding block mechanisms, the target bottles with different heights are picked up through the vertically arranged guide rail sliding block mechanisms, because the linear displacement of the horizontal shaking liquid chuck 47 is controlled through a cylinder, the influence of vibration on the displacement is reduced through fastening connection, in order to improve the integration performance of the horizontal shaking liquid device 4, a guide rail is arranged on the horizontal shaking liquid sliding block 43, a sliding block is arranged on one side of the first motor 46, the output end of the horizontal shaking liquid cylinder 44 is fastened and connected with the sliding block of the first motor 46, and the first motor 46 is precisely, first motor 46 output and horizontal turntable 45 fastening connection, rotate control horizontal turntable 45 through first motor 46 and rotate along the axle center, make the culture solution in the target bottle mix gradually through rotating, be equipped with a plurality of horizontal shaking liquid chuck 47 on horizontal turntable 45 lower surface, can control a plurality of target bottles and rotate, improve work efficiency, control horizontal shaking liquid chuck 47 through small-size cylinder and press from both sides tight target bottle bottleneck, small-size cylinder of every horizontal shaking liquid chuck 47 configuration, carry out the independent control to horizontal shaking liquid chuck 47, add a guide post slider mechanism on horizontal shaking liquid crossbeam 42, and guide rail slider mechanism cooperation, carry out two-way location to horizontal migration, make the displacement accuracy higher.
As shown in fig. 7 to 9, the vertical shaking device 5 comprises a vertical shaking support 51, a vertical shaking beam 52, a vertical shaking slide block 53, a vertical shaking cylinder 54, a vertical turntable 55, a second motor 56, a second guide column 58 and a second slide block 59, wherein the top end of the vertical shaking support 51 is fixedly connected with one side of the vertical shaking beam 52, the bottom end of the vertical shaking support 51 is fixedly connected with the mounting plate 13, a vertical shaking guide rail 521 is arranged on one side of the vertical shaking beam 52, the vertical shaking slide block 53 is slidably connected with the vertical shaking guide rail 521, one side of the vertical shaking slide block 53 is fixedly connected with the vertical shaking cylinder 54, a vertical guide rail perpendicular to the vertical shaking guide rail 521 is arranged on one side of the vertical shaking slide block 53, a slide block is arranged on one side of the second motor 56, a slide block of the second motor 56 is slidably connected with the vertical guide rail of the vertical shaking slide block 53, the output end of the vertical shaking cylinder 54 is fixedly connected with the slide block of, the output end of the second motor 56 is fixedly connected with the vertical rotary disc 55, the bottom surface of the vertical rotary disc 55 is provided with a plurality of vertical liquid shaking chucks 57, one side of the vertical liquid shaking beam 52 is provided with a guide column mounting groove, the second guide column 58 is fixedly connected with the end surface of the guide column mounting groove of the vertical liquid shaking beam 52, the first sliding block 49 is slidably connected with the second guide column 58, and the second sliding block 59 is fixedly connected with the vertical liquid shaking sliding block 53 far away from one side of the second guide column 58.
The target bottle after horizontal shaking is sent to the screwing manipulator 6, the screwing manipulator 6 unscrews the target bottle cap, the target bottle is injected with culture solution again through the liquid injection manipulator 8 along with the rotation of the rotating disc 74, the bottle cap is screwed down through the screwing manipulator 6 after the liquid injection again, the horizontal shaking cannot enable the culture solution to be mixed more uniformly along with the increase of the components of the culture solution, the culture solution is further mixed through the vertical shaking device 5, the culture solution is not layered for two times through mixing, the connection among the vertical shaking bracket 51, the vertical shaking beam 52 and the mounting plate 13 is tighter through fastening connection, the positioning error caused by external collision is weakened, the vertical shaking guide rail 521 is arranged on one side of the vertical beam, the horizontal displacement is guided through sliding connection with the vertical shaking slide block 53, the bidirectional positioning is realized through the guide column slide block mechanism, the positioning precision is improved, one side of the vertical shaking cylinder 54 is fastened and connected with the vertical shaking slide block 53, the vertical displacement mechanism moves horizontally along with the movement of the sliding block, then the second motor 56 moves along the vertical direction through the vertical liquid shaking guide rail 521 arranged on the vertical liquid shaking sliding block 53, along with the downward movement of the second motor 56, a plurality of vertical liquid shaking chucks 57 arranged on the vertical rotary disc 55 touch the target bottle mouth, the target bottle mouth is clamped by controlling the vertical liquid shaking chucks 57 through a small-sized cylinder, in order to prevent the target bottle from colliding with other devices when the vertical rotary disc 55 rotates, the height of the chucks is raised through the vertically arranged guide rail sliding block mechanism, the vertical rotary disc 55 is far away from the screwing manipulator 6 through the horizontally arranged guide rail sliding block mechanism, the second motor 56 drives the vertical rotary disc 55 to rotate along the axis, the target bottle rotates along with the target bottle, the culture liquid in the target bottle is overturned and mixed on the vertical plane, the mixing degree of the culture liquid in the target bottle is further raised, and the total number of the vertical liquid shaking, pick up in turn to the target bottle, shortened the latency that vertical liquid shaking chuck 57 pressed from both sides and get the target bottle, set up a plurality of vertical liquid shaking chucks 57 and can constantly pick up the target bottle along with the carousel rotates under the vertical carousel 55, then through the drive of second motor 56, shake liquid to a plurality of target bottles simultaneously, improve the efficiency of shaking liquid greatly.
As shown in fig. 1 and 10, the power transmission device 7 includes a driving motor 71, a speed reducer 72, a flange turntable 73, a rotating disc 74, a speed reducer support 74 and an auxiliary rotating assembly 76, one side of the driving motor 71 is rotatably connected with the speed reducer 72, the speed reducer 72 is fixedly connected with the speed reducer support 74, the speed reducer support 74 extends upwards to form a support column, the support column of the speed reducer support 74 is fixedly connected with the mounting plate 13, the speed reducer 72 is fixedly connected with the flange turntable 73, the bottom end of the flange turntable 73 is fixedly connected with the rotating disc 74, a plurality of auxiliary rotating assemblies 76 are arranged on the lower surface of the rotating disc 74, each auxiliary rotating assembly 76 includes a rotating wheel 761 and a rotating wheel support 762, and the rotating wheel 761.
The invention takes the driving motor 71 as the main power source of the power transmission device 7, in order to improve the stability among all parts, the influence of vibration on torque transmission is reduced through fastening connection, the output torque of the driving motor 71 is directly connected to the rotating disc 74, because the rotating speed of the driving motor 71 is too high, force transmission is unstable and inconvenient to rotate, the output rotating speed is reduced through the speed reducer 72, and the reduced torque is transmitted to the rotating disc 74 through the flange rotating disc 73, because the contact surface between the flange rotating disc 73 and the rotating disc 74 is larger, the torque output is more stable, in order to reduce the radial force to the output shaft of the speed reducer 72 when the rotating disc 74 rotates, a plurality of auxiliary rotating assemblies 76 are arranged at the bottom end of the rotating disc 74 along the circumferential direction, the rotating disc 74 is installed on the rotating disc 74 through the rotating wheel bracket 762, and the rotating wheel 761 rolls on the surface of the installation plate 13 along, the rotating disc 74 is supported, and the rotating smoothness of the rotating disc 74 is further improved.
Biological cell schizolysis preparation workstation still includes except that liquid manipulator 3, removes 3 bottoms of liquid manipulator and mounting panel 13 fastening connection, is equipped with a plurality of notes liquid manipulator 8 on the mounting panel 13, annotates liquid manipulator 8 and mounting panel 13 fastening connection, and rolling disc 74 one side is equipped with a plurality of screwing in machines hand 6 along the circumferencial direction, and screwing in machines hand 6 bottoms and rolling disc 74 fastening connection.
After a target bottle is sent to a screwing manipulator 6 to be uncapped, the target bottle is clamped out through a liquid removing manipulator 3, the target bottle is inverted, residual liquid in the target bottle after cleaning is removed, residual liquid is collected through a connecting disc at the bottom end of the liquid removing manipulator 3, multi-component culture solution can be prepared through a plurality of arranged liquid injection manipulators 8, each manipulator controls an air cylinder to work through a controller, vibration is large, work is smoother through fastening connection, a plurality of screwing manipulators 6 are arranged on a rotating disc 74 to improve work efficiency, each station corresponds to at least one screwing manipulator 6, transmission paths between adjacent stations are reduced, liquid injection efficiency is improved, the screwing manipulators 6 have the function of code spraying on the target bottle besides cap screwing manipulator operation, the target bottle can be conveniently distinguished in large batch, particularly when the culture solution is prepared, the classification efficiency is greatly improved.
The working principle of the invention is as follows: according to the invention, the target bottles for preparing the biological cells by cracking are mechanically configured in batches to replace manual configuration, the target bottles are automatically fed by the feeding and discharging device 2, the horizontal shaking device 4 and the vertical shaking device 5 are additionally arranged on the upper surface of the mounting plate 13, and culture solution is uniformly mixed by alternately rotating the horizontal surface and the vertical surface, a closed space is formed between the upper rack 11 and the mounting plate 13, the target bottles are kept sealed when entering the tool device, and only opening injection is carried out in the device; set up two sets of guide rail slider mechanisms on horizontal shaking liquid device 4, the guide rail slider mechanism through the level arrangement makes the target bottle move along the direction that the spiral-closure manipulator 6 was kept away from to the horizontal direction, other spare part are not collided during the horizontal shaking liquid, pick up the target bottle of co-altitude through the guide rail slider mechanism of vertical arrangement, through arranging a plurality of supplementary rotating assembly 76 in rolling disc 74 bottom along the circumferencial direction, along with the rolling disc 74 rotates, runner 761 rolls on mounting panel 13 surface, play the supporting role to rolling disc 74, spiral-closure manipulator 6 still has the function of spouting the sign indicating number to the target bottle except carrying out the spiral cover operation, classify the target bottle.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (7)

1. A biological cell lysis preparation workstation characterized by: the preparation workstation includes box subassembly (1), last unloader (2), level shake liquid device (4), vertical shake liquid device (5) and power transmission device (7), go up unloader (2) and box subassembly (1) fastening connection, the box subassembly includes mounting panel (13), horizontal shake liquid device (4) is installed in mounting panel (13) upper end one side, vertical shake liquid device (5) are installed and are kept away from horizontal shake liquid device (4) one side in mounting panel (13) upper end, power transmission device and mounting panel (13) fastening connection.
2. A biological cell lysis preparation station according to claim 1 wherein: the box body assembly (1) further comprises an upper frame (11), a lower frame (12) and an alarm lamp (14), one side of the upper frame (11) is connected with a mounting plate (13) in a sealing mode, one side of the lower frame (12) is connected with the mounting plate (13) in a fastening mode, one side of the upper frame (11) is connected with the mounting plate (13) in a fastening mode, and the alarm lamp (14) is mounted at the upper end of the upper frame (11).
3. A biological cell lysis preparation station according to claim 1 wherein: the feeding and discharging device (2) comprises a feeding assembly (21), a transmission assembly (22) and a wire protection chain (24), a plurality of safety baffles (23) are arranged at the upper end of the feeding assembly (21), the feeding assembly (21) is fixedly connected with a mounting plate (13), the transmission assembly (22) is fixedly connected with one side of the wire protection chain (24), the feeding assembly (21) comprises a feeding cylinder (211), a feeding stacking block (212), a transmission block (213) and a stacking support (214), one side of the feeding cylinder (211) is fixedly connected with the stacking support (214), the output end of the feeding cylinder (211) is fixedly connected with the transmission block (213), feeding guide rails (215) are arranged on two sides of the bottom end of the feeding stacking block (212), a sliding block is arranged at the top end of the stacking support (214), the sliding block of the stacking support (214) is slidably connected with the feeding guide rails (215), and the middle of the bottom end of the feeding stacking block (212) is fixedly connected with the transmission block (213), the transmission assembly (22) is fastened and connected with the mounting plate (13), the transmission assembly (22) comprises a sliding cylinder (221), a lead screw (222), a nut (223), a bearing seat (224), a transmission support (225), a transmission chuck (226), a chuck fixing plate (227), a transmission cylinder (228) and a transmission slider (229), one side of the sliding cylinder (221) is fastened and connected with the transmission support (225), the output end of the sliding cylinder (221) is fastened and connected with one side of the lead screw (222), two ends of the lead screw (222) are movably connected with the bearing seat (224), one end of the transmission support (225) is provided with a mounting cavity, the bearing seat (224) is fastened and connected with the inner wall surface of the mounting cavity of the transmission support (225), the nut (223) is connected with the lead screw (222) in a threaded manner, the outer circular surface of the nut (223) is fastened and connected with one side of the transmission slider (229), one side of the transmission, the bottom end of the transmission support (225) is fixedly connected with the mounting plate (13), a transmission guide rail (2251) is arranged on one side of the transmission support (225), the transmission sliding block (229) is slidably connected with the transmission guide rail (2251), a guide rail is arranged on one side of the transmission sliding block (229), the guide rail of the transmission sliding block (229) is perpendicular to the direction of the transmission guide rail (2251), a sliding block is arranged on one side of the chuck fixing plate (227), the sliding block of the chuck fixing plate (227) is slidably connected with the guide rail of the transmission sliding block (229), one side of the transmission cylinder (228) is fixedly connected with the transmission sliding block (229), the output end of the transmission cylinder (228) is fixedly connected with the chuck fixing plate (227), and the chuck fixing plate (227) is fixedly connected with the transmission.
4. A biological cell lysis preparation station according to claim 1 wherein: the horizontal shaking liquid device (4) comprises a horizontal shaking liquid bracket (41), a horizontal shaking liquid beam (42), a horizontal shaking liquid sliding block (43), a horizontal shaking liquid cylinder (44), a horizontal rotary table (45), a first motor (46), a first guide column (48) and a first sliding block (49), wherein the top end of the horizontal shaking liquid bracket (41) is fixedly connected with one side of the horizontal shaking liquid beam (42), the bottom end of the horizontal shaking liquid bracket (41) is fixedly connected with a mounting plate (13), a horizontal shaking liquid guide rail (421) is arranged on one side of the horizontal shaking liquid beam (42), the horizontal shaking liquid sliding block (43) is slidably connected with the horizontal shaking liquid guide rail (421), the top end of the horizontal shaking liquid sliding block (43) is fixedly connected with the horizontal shaking liquid cylinder (44), a vertical guide rail perpendicular to the horizontal shaking liquid guide rail (421) is arranged on one side of the horizontal shaking liquid sliding block (43), and a sliding block is arranged on one side of the first motor (46), first motor (46) slider and the vertical guide rail sliding connection of horizontal rocking liquid slider (43), horizontal rocking liquid cylinder (44) output and first motor (46) slider fastening connection, first motor (46) output and horizontal rotating disc (45) fastening connection, horizontal rotating disc (45) bottom surface is equipped with a plurality of horizontal rocking liquid chucks (47), horizontal rocking liquid crossbeam (42) one side is equipped with the guide post mounting groove, first guide post (48) and horizontal rocking liquid crossbeam (42) guide post mounting groove terminal surface fastening connection, first slider (49) and first guide post (48) sliding connection, first guide post (48) one side and horizontal rocking liquid slider (43) fastening connection are kept away from in first slider (49).
5. A biological cell lysis preparation station according to claim 1 wherein: the vertical liquid shaking device (5) comprises a vertical liquid shaking support (51), a vertical liquid shaking crossbeam (52), a vertical liquid shaking sliding block (53), a vertical liquid shaking cylinder (54), a vertical rotary disc (55), a second motor (56), a second guide column (58) and a second sliding block (59), wherein the top end of the vertical liquid shaking support (51) is fixedly connected with one side of the vertical liquid shaking crossbeam (52), the bottom end of the vertical liquid shaking support (51) is fixedly connected with a mounting plate (13), a vertical liquid shaking guide rail (521) is arranged on one side of the vertical liquid shaking crossbeam (52), the vertical liquid shaking sliding block (53) is slidably connected with the vertical liquid shaking guide rail (521), one side of the vertical liquid shaking sliding block (53) is fixedly connected with the vertical liquid shaking cylinder (54), a vertical guide rail perpendicular to the vertical liquid shaking guide rail (521) is arranged on one side of the vertical liquid shaking sliding block (53), and a sliding block is arranged on one side of the second motor (56), the liquid shaking device is characterized in that a second motor (56) sliding block is connected with a vertical liquid shaking sliding block (53) in a sliding mode through a vertical guide rail, an output end of a vertical liquid shaking cylinder (54) is connected with the second motor (56) sliding block in a fastening mode, an output end of the second motor (56) is connected with a vertical rotating disc (55) in a fastening mode, a plurality of vertical liquid shaking clamping heads (57) are arranged on the bottom surface of the vertical rotating disc (55), a guide column mounting groove is formed in one side of a vertical liquid shaking cross beam (52), a second guide column (58) is connected with the end face of the guide column mounting groove of the vertical liquid shaking cross beam (52) in a fastening mode, the first sliding block (59) is connected with the second guide column (58) in a sliding mode, and the second sliding block (59) is far away from one side of the.
6. A biological cell lysis preparation station according to claim 1 wherein: the power transmission device (7) comprises a driving motor (71), a speed reducer (72), a flange turntable (73), a rotating disc (74), a speed reducer bracket (75) and an auxiliary rotating assembly (76), one side of the driving motor (71) is rotationally connected with a speed reducer (72), the speed reducer (72) is tightly connected with a speed reducer bracket (75), the speed reducer bracket (75) extends upwards to be provided with a supporting column, the supporting column of the speed reducer bracket (75) is fixedly connected with the mounting plate (13), the speed reducer (72) is tightly connected with the flange turntable (73), the bottom end of the flange turntable (73) is tightly connected with the rotating disc (74), a plurality of auxiliary rotating assemblies (76) are arranged on the lower surface of the rotating disc (74), the auxiliary rotating assembly (76) comprises a rotating wheel (761) and a rotating wheel support (762), and the rotating wheel (761) is movably connected with the rotating wheel support (762).
7. A biological cell lysis preparation workstation as claimed in claim 6 wherein: the preparation workstation is still including removing liquid manipulator (3), remove liquid manipulator (3) bottom and mounting panel (13) fastening connection, be equipped with a plurality of notes liquid manipulator (8) on mounting panel (13), annotate liquid manipulator (8) and mounting panel (13) fastening connection, rolling disc (74) one side is equipped with a plurality of hands of closing soon (6) along the circumferencial direction, close manipulator (6) bottom and rolling disc (74) fastening connection soon.
CN202110096151.1A 2021-01-25 2021-01-25 Biological cell lysis preparation workstation Pending CN112812950A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110096151.1A CN112812950A (en) 2021-01-25 2021-01-25 Biological cell lysis preparation workstation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110096151.1A CN112812950A (en) 2021-01-25 2021-01-25 Biological cell lysis preparation workstation

Publications (1)

Publication Number Publication Date
CN112812950A true CN112812950A (en) 2021-05-18

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110096151.1A Pending CN112812950A (en) 2021-01-25 2021-01-25 Biological cell lysis preparation workstation

Country Status (1)

Country Link
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115180583A (en) * 2022-07-25 2022-10-14 展一智能科技(东台)有限公司 Method for opening and closing cover of packaging barrel

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115180583A (en) * 2022-07-25 2022-10-14 展一智能科技(东台)有限公司 Method for opening and closing cover of packaging barrel
CN115180583B (en) * 2022-07-25 2024-04-26 展一智能科技(苏州)有限公司 Method for opening and closing cover of packaging barrel

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