CN112810046A - Thermoplastic forming die of implanted flexible magnetic control bladder pump - Google Patents
Thermoplastic forming die of implanted flexible magnetic control bladder pump Download PDFInfo
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- CN112810046A CN112810046A CN202110163986.4A CN202110163986A CN112810046A CN 112810046 A CN112810046 A CN 112810046A CN 202110163986 A CN202110163986 A CN 202110163986A CN 112810046 A CN112810046 A CN 112810046A
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Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/14—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
- B29C45/14336—Coating a portion of the article, e.g. the edge of the article
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/17—Component parts, details or accessories; Auxiliary operations
- B29C45/26—Moulds
- B29C45/2602—Mould construction elements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
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- Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Mechanical Engineering (AREA)
- Prostheses (AREA)
Abstract
The invention relates to a thermoplastic forming die of an implanted flexible magnetic control bladder pump, which comprises: the mold core consists of a mold core main body and a mold core handle, the shape of the mold core main body is adapted to the shape of the filled bladder, and the shape of the mold core handle is adapted to the shape of the urethra connected with the bladder; the top of the front mould box is provided with a plurality of slots matched with the front mould box plug block group; a front accommodating chamber is arranged in the front mould box; the top of the rear molding box is provided with a jack matched with the rear molding box insert block; a rear accommodating chamber is arranged in the rear molding box; the mold core handle is arranged in the back mold accommodating cavity. The implanted flexible magnetic control bladder pump prepared by the thermoplastic forming die can effectively and permanently solve difficult urination diseases such as nerve bladder dysfunction and the like, and after the flexible magnetic control bladder pump is implanted through an operation, the function of normal urination can be realized through the large moment of magnetic force exerted by an external magnetic field under the condition of not connecting any extra external pipeline.
Description
Technical Field
The invention relates to the technical field of biomedicine, in particular to a thermoplastic forming die of an implanted flexible magnetic control bladder pump.
Background
The rapid development of soft robots for biomedical applications aims to improve medical conditions and provide novel therapeutic tools such as surgical instruments, body simulation and drug delivery. As an active system with high compliance and biocompatibility, the soft robot has wide prospect in assisting the movement of organs and even reconstructing the organs. Efforts have been made to use soft-body robots in prosthetic aids to cope with various diseased muscles, such as the myocardium, hand muscles and sphincters.
The low functional bladder (UAB) is characterized by prolonged urination time due to weakness of muscles, leading to serious complications and even death, and the incidence of UAB is high, with 9-98% in men and 12-45% in women, affected by aging, neurological diseases, trauma, diabetes, etc. Neuro-based therapies represented by neuromodulation (SNM) have shown potential to overcome OAB (overactive bladder)/DU (detrusor hypoactivity). However, a complete micturition reflex arc neural circuit is essential to achieve the clinical efficacy of SNM, suggesting that the device is not suitable for patients with sacral or pudendal nerve injury or with pathological detrusor muscle.
Unlike current solutions, increasing the force of detrusor contraction is a direct and fundamental solution to voiding the bladder. Attempts have been made to restore detrusor contractile capacity through regenerative medical strategies (e.g., muscle transplantation and stem cell injection). However, these methods only partially restore the urine storage function of the bladder, and the risk-to-benefit ratio remains to be further evaluated in a wider range of OAB/DU patients.
At present, the problem of bladder urination dysfunction is difficult to solve by adopting methods such as medicines, electrical stimulation, operations, body nerve reflex treatment and the like or by adopting auxiliary urination measures such as abdominal pressure, drainage, diversion and the like, is one of the problems acknowledged by the medical field, and the problem of difficulty in urination weakness when bladder muscle contraction dysfunction exists is solved effectively is the problem which needs to be solved urgently by technical personnel in the field at present.
Several solutions for directly pressing the bladder based on a contact type hydraulic system directly implanted by a soft robot are proposed in the prior art, and are named as Endoskeleton/artificial detrusor muscle. These intravesical pressure maintenance system driving forces are mainly derived from thermally responsive gels or shape memory alloys, intended to encapsulate the bladder and physically contract in response to stimuli. Previous research results have shown that these mechanical strategies effectively increase intravesical pressure, ameliorate the problem of hypodynamic bladder, and that, while encouraging results have been achieved, existing artificial detrusor muscles provide limited hydraulic pressure, far from human muscle levels, due to the relatively inefficient operation of the stimulation source. In addition, current soft bladder assisted robotic systems do not enable reliable long-term functionality due to lack of realistic medical design and optimization of biological safety.
Disclosure of Invention
The application provides a thermoplastic forming die of an implanted flexible magnetic control bladder pump, which solves or partially solves the technical problems that in the prior art, the hydraulic pressure provided by an artificial detrusor is limited, is far from the level of human muscles, is lack of practical medical design and optimization of biological safety, and cannot realize reliable long-term functions; the provided thermoplastic forming die enables the implanted flexible magnetic control bladder pump prepared by the thermoplastic forming die to effectively and permanently solve difficult urination diseases such as nerve bladder dysfunction and the like, and after the flexible magnetic control bladder pump is implanted through an operation, the normal urination function can be realized through the large moment of magnetic force exerted by an external magnetic field under the condition of not connecting any extra external pipeline.
According to the thermoplastic forming die of the implanted flexible magnetic control bladder pump, the implanted flexible magnetic control bladder pump is a flexible magnetic control inclusion formed by combining a flexible non-magnetic base body and a ferromagnetic complex; the implanted flexible magnetic control bladder pump is adapted to the shape of the inflated bladder, and a movable cavity wrapping the bladder is arranged in the implanted flexible magnetic control bladder pump; the thermoplastic forming die comprises: a core, a front molding box, a rear molding box, a front molding box insert block group and a rear molding box insert block, wherein,
the mold core consists of a mold core main body and a mold core handle, and the mold core handle is in inserted sliding connection with the mold core main body; the shape of the core main body is adapted to the shape of the inflated bladder, and the shape of the core handle is adapted to the shape of the urethra connected with the bladder; the position of the core body close to the core handle is provided with a bulge for forming a ureteral orifice and a cut of the implanted flexible magnetic control bladder pump;
the top of the front mould box is provided with a plurality of slots matched with the front mould box plug block group; a front accommodating chamber is arranged in the front molding box; when the core main body is placed in the front mould accommodating cavity, the ferromagnetic complex body positioned at the lower part of the core main body is tightly attached to the inner bottom surface of the front mould box; the gap formed after the front mould box, the front mould box insert block group and the core main body are assembled is a main body injection molding cavity, and the flexible nonmagnetic matrix in a hot melting state is injected into the main body injection molding cavity through the slot to form a main body part of the flexible magnetic control inclusion;
the top of the rear molding box is provided with a jack matched with the rear molding box insert block; a rear accommodating chamber is arranged in the rear molding box; the core handle is arranged in the back mold accommodating cavity; the gap formed after the rear mould box, the rear mould box insert block and the core handle are assembled is a urethra injection molding cavity, and the flexible non-magnetic matrix in a hot melting state is injected into the urethra injection molding cavity through the insertion hole to form a urethra coating body of the flexible magnetic control coating body.
Preferably, the drag mold comprises: a front-type box bottom layer structure body, a front-type box middle layer front end structure body, a front-type box middle layer rear end first structure body, a front-type box middle layer rear end second structure body and a front-type box top layer structure body, wherein,
the top surface of the front mould box bottom layer structure body is matched with the bottom surface of the implanted flexible magnetic control bladder pump in shape;
the front mould box middle layer front end structure body is arranged at the front end above the front mould box bottom layer structure body in a sliding manner; a positioning slide rod is arranged at the front end of the front structure body in the middle layer of the front mould box, and a positioning slide groove is arranged in the front structure body at the bottom layer of the front mould box corresponding to the positioning slide rod;
the first structure body at the rear end of the middle layer of the front mould box is movably arranged at the rear end of the left side above the structure body at the bottom layer of the front mould box, and the first structure body at the rear end of the middle layer of the front mould box is hinged with the structure body at the bottom layer of the front mould box;
the second structure body at the rear end of the middle layer of the front mould box is movably arranged at the rear end of the right side above the structure body at the bottom layer of the front mould box, and the second structure body at the rear end of the middle layer of the front mould box is hinged with the structure body at the bottom layer of the front mould box;
the front mould box top structure body is hinged on the front end structure body of the front mould box middle layer;
the core main body and the front mould box bottom layer structure body, the front mould box middle layer front end structure body, the front mould box middle layer rear end first structure body, the front mould box middle layer rear end second structure body, the front mould box top layer structure body and the front mould box plug block group are assembled to form the main body injection molding cavity.
Preferably, the shape of the bottom surface of the front box top structure is adapted to the arrangement shape of the ferromagnetic composite body on the upper part of the core main body; and after the front molding box top structure body is turned over to be right above the front molding box middle layer front end structure body, the bottom surface of the front molding box top structure body is attached to the top surfaces of all the ferromagnetic complex bodies, and the positions of the slots respectively correspond to the gap positions of the ferromagnetic complex bodies.
Preferably, the front mould box further comprises a first net belt limiting group and a second net belt limiting group,
the first mesh belt limiting group comprises two first mesh belt limiting frames which are respectively arranged on the left side and the right side of the front mould box bottom layer structure body; when the main body part of the flexible magnetic control inclusion body is manufactured, one ends of two first operation mesh belts pass through the corresponding first mesh belt limiting frames and then are introduced into the main body injection molding cavity;
the second mesh belt limiting group comprises two second mesh belt limiting frames which are respectively arranged on the first structural body at the rear end of the middle layer of the front molding box and the second structural body at the rear end of the middle layer of the front molding box; and when the main body part of the flexible magnetic control inclusion body is manufactured, one ends of two second operation mesh belts pass through the corresponding second mesh belt limiting frames and then are introduced into the main body injection molding cavity.
Preferably, the two sides of the front mold box bottom layer structure, the front mold box middle layer front end structure and the front mold box top layer structure extend outwards to form binding convex blocks respectively, and after the core body is placed in the front mold accommodating cavity of the front mold box, the core body is fixedly sleeved on the binding convex blocks on each side through two binding hoops respectively, so that the front mold box bottom layer structure, the front mold box middle layer front end structure and the front mold box top layer structure are fixed into a whole.
Preferably, the back mold comprises: a back molding box bottom layer structure body, two back molding box middle layer structure bodies, a back molding box top layer structure body and a back cover, wherein,
the rear mould box bottom structure is provided with a rear mould accommodating chamber for placing the mould core handle; the butt joint surface of the rear molding box bottom structure body and the front molding box is respectively provided with a positioning lug and a positioning groove matched with the positioning lug;
the two rear molding box middle layer structural bodies are respectively arranged at two sides above the rear molding box bottom layer structural body; the butt joint surface of the rear molding box middle layer structure body and the rear molding box bottom layer structure body is respectively provided with a positioning lug and a positioning groove matched with the positioning lug;
the rear molding box top layer structure body is arranged above the two rear molding box middle layer structure bodies, and the butt joint surfaces of the rear molding box top layer structure body and the rear molding box middle layer structure body are respectively provided with a positioning lug and a positioning groove matched with the positioning lug;
the rear cover is arranged at the rear end of the rear molding box bottom structure body, and a positioning lug and a positioning groove matched with the positioning lug are respectively arranged on the butt joint surface of the rear cover and the rear molding box bottom structure body; the rear cover is assembled and then clings to the rear end surfaces of the rear molding box bottom structure body, the two rear molding box middle structure bodies and the rear molding box top structure body;
the core handle, the back mould box bottom structure, the two back mould box middle structure, the back mould box top structure, the back cover and the back mould box insert block are assembled to form the urethra injection molding cavity.
Preferably, binding lugs extend outwards from two sides of the rear molding box bottom structure, the two rear molding box middle structure and the rear molding box top structure respectively, and the core handle is placed in the rear accommodating cavity of the rear molding box and then is fixedly sleeved on the binding lugs on each side through two binding hoops respectively so as to fix the rear molding box bottom structure, the two rear molding box middle structure and the rear molding box top structure into a whole;
binding convex blocks extend outwards from the corresponding positions of the two side ends of the rear molding box bottom structure and the side end of the front molding box respectively, and are fixedly sleeved on the binding convex blocks on each side through two binding clamp rings respectively so as to fix the front molding box and the rear molding box bottom structure into a whole;
binding convex blocks extend outwards from the outer side end of the middle layer structure of the rear molding box and the corresponding positions of the side end of the front molding box respectively, and are fixedly sleeved on the binding convex blocks on each side through two binding clamp hoops respectively so as to fix the front molding box and the middle layer structure of the rear molding box into a whole;
and binding convex blocks extend outwards from the corresponding positions of the two side ends of the rear molding box top layer structure body and the side end of the front molding box respectively, and are fixedly sleeved on the binding convex blocks on each side through two binding clamp rings respectively so as to fix the front molding box and the rear molding box top layer structure body into a whole.
Preferably, a slide shaft with a positioning key extends from the center of the end part of the core main body; the center of the core handle is provided with a shaft hole corresponding to the sliding shaft; the core handle is sleeved on the sliding shaft, and the core handle is slid to a position attached to the end face of the core main body when the core is assembled.
Preferably, when the implantable flexible magnetically controlled bladder pump is manufactured, the ferromagnetic composite body is fixed at a set position on the surface of the core main body through medical mesh pasting.
Preferably, the middle position of the ferromagnetic composite body in the thickness direction is provided with a split mesh opening; the medical mesh passes through the split mesh opening and is adhered to the surface of the mold core through glue; the ferromagnetic complex at the mesh opening is bonded with the medical mesh by glue.
One or more technical solutions provided in the embodiments of the present application have at least the following technical effects or advantages:
the thermoplastic forming die of the implanted flexible magnetic control bladder pump is provided with a structure consisting of a core, a front molding box, a rear molding box, a front molding box insert block group and a rear molding box insert block; a gap formed after the front mould box, the front mould box insert block group and the core main body are assembled is a main body injection molding cavity, and a hot-melt flexible nonmagnetic matrix is injected into the main body injection molding cavity through the insert slot to form a main body part of a flexible magnetic control inclusion; the gap formed after the rear mould box, the rear mould box insert block and the core handle are assembled is a urethra injection molding cavity, the flexible non-magnetic matrix in a hot melting state is injected into the urethra injection molding cavity through the jack to form a urethra coating body of the flexible magnetic control coating body, so that the implanted flexible magnetic control bladder pump conformal to the filled bladder is successfully manufactured, the manufactured flexible magnetic control bladder pump is sleeved on the neurogenic bladder, the flexible magnetic control bladder pump is enabled to carry out contact type extrusion to empty the bladder, and then the urination function of the disabled bladder is rebuilt.
This mould is moulded to heat adopts modular integrated configuration to be convenient for manufacturing, and the structure is exquisite, and the dismouting is simple to be convenient for maintain and change parts, and the simple operation during the use has guaranteed higher moulding manufacturing efficiency of heat.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is an exploded view of a thermoplastic molding tool according to an exemplary embodiment of the present disclosure;
FIG. 2 is a first state diagram of a molding tool during a filling phase according to an embodiment of the present disclosure;
FIG. 3 is a first state diagram illustrating a filling phase of a thermoforming mold according to an embodiment of the present disclosure;
FIG. 4 is a drawing of a first state of a thermoplastic forming die at an assembly stage according to an embodiment of the present application;
FIG. 5 is a drawing of a second state of the thermoplastic molding tool at an assembly stage according to an embodiment of the present application;
FIG. 6 is a drawing of a third stage of assembly of a thermoplastic molding tool according to an embodiment of the present application;
FIG. 7 is a drawing of a fourth phase of the assembly stage of a thermoplastic forming die according to embodiments of the present application;
FIG. 8 is a schematic view of a first configuration of a mandrel body provided in accordance with an embodiment of the present application;
FIG. 9 is a second schematic view of a core body provided in accordance with an embodiment of the present application;
fig. 10 is a schematic diagram of a first configuration of an implantable flexible magnetically controlled bladder pump provided in an embodiment of the present application;
fig. 11 is a second structural schematic diagram of the implantable flexible magnetically controlled bladder pump provided in the embodiment of the present application.
(the components represented by each reference number in the drawing are sequentially 1 front mould case, 11 front mould case bottom layer structure body, 12 front mould case middle layer front end structure body, 13 front mould case middle layer rear end first structure body, 14 front mould case middle layer rear end second structure body, 15 front mould case top layer structure body, 16 second net belt limiting group, 17 first net belt limiting group, 2 back mould case, 21 back mould case bottom layer structure body, 22 back mould case middle layer structure body, 23 back mould case top layer structure body, 24 back cover, 25 positioning lug, 26 positioning groove, 3 front mould case insert block group, 4 back mould case insert block, 5 core, 51 core main body, 52 core handle, 53 sliding shaft, 54 bulge, 55 medical net sheet, 61 second surgical net sheet, 62 first surgical net sheet, 63 third surgical net sheet, 71 fixing lug, 72 binding hoop, 811 first magnetic force strip, 812 second magnetic force strip, 82 flexible base body, 83 urethra body coating, 84 ureter hole, 85 cut)
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are some embodiments of the present application, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
Referring to fig. 10 and 11, the implanted flexible magnetically controlled bladder pump provided by the present application is a flexible magnetically controlled inclusion formed by combining a flexible non-magnetic substrate 82 and a ferromagnetic complex; the flexible magnetic control inclusion is adapted to the shape of the inflated bladder, and a movable cavity for wrapping the bladder is arranged in the flexible magnetic control inclusion.
The flexible magnetic control inclusion body is provided with a notch 85 corresponding to the position of the bladder connecting the urethra and the ureter, and the bladder is sent into the movable cavity of the flexible magnetic control inclusion body through the notch 85; two ureter holes 84 are formed in the positions, corresponding to the ureters, of the flexible magnetron wrapping bodies, and the two ureter holes 84 are located at two ends of the cut 85.
The flexible magnetic control wrapping body extends to form a urethra wrapping body 83 corresponding to the urethra, the material of the urethra wrapping body 83 is the same as that of the flexible non-magnetic base body 82, and the length of the urethra wrapping body 83 can be designed to be equal to that of the urethra. The urethra coating body 83 is designed to prevent the bladder body from sliding out of the movable cavity of the flexible magnetic control coating body, and meanwhile, the flexible magnetic control coating body is convenient to fix on the pelvis.
The urethral coating body 83 includes: a first semi-circular stem tube, a second semi-circular stem tube, a first stem tube extension and a second stem tube extension, both formed by extending a flexible non-magnetic matrix 82 axially along the urethra; the first semicircular stem pipe and the second semicircular stem pipe are butted to form a stem pipe capable of wrapping the urethra; the first and second stem extension portions are formed by extending the first semicircular stem tube in the circumferential direction of the urethra, or the first and second stem extension portions are formed by extending the second semicircular stem tube in the circumferential direction of the urethra, and the first and second stem extension portions can wrap the stem tube after being butted.
After the bladder is placed in the movable cavity of the flexible magnetic control inclusion body, the incision 85 between the ureter hole 84 and the urethra inclusion body 83 is sewed through a medical suture; the first and second stalk extension portions are sutured together with a medical suture.
The flexible magnetic control inclusion body is divided into a front extrusion part and a back positioning part, the front extrusion part is close to the peritoneum of the organism, and the back positioning part is close to the pubis of the organism; the ferromagnetic composite body comprises a plurality of first magnetic strips 811, and the plurality of first magnetic strips 811 are arranged in the front extrusion part at intervals side by side. In the urination process, the front-surface squeezing part is close to the back-surface positioning part under the action of an external magnetic field to form a pressing effect, and the function of a detrusor is achieved.
The ferromagnetic composite body further comprises a plurality of second magnetic strips 812, and the plurality of second magnetic strips 812 are distributed on two sides of the back positioning portion at intervals side by side. The back positioning part of the flexible magnetic control inclusion is provided with a plurality of second magnetic strips 812, the back positioning part is tightly attached to the pubis under the action of an external magnetic field, free sliding of the front extrusion part in the pressing process of the flexible magnetic control inclusion can be effectively prevented, and the bladder extrusion action stability is guaranteed.
The fixing component comprises 3 pairs of operation mesh belts which are respectively arranged on the flexible magnetic control inclusion body, namely a first operation mesh belt 62, a second operation mesh belt 61 and a third operation mesh belt 63; one end of the operation mesh belt is embedded into the flexible non-magnetic matrix 82 and fixed into a whole through physical bonding, and the other end of the operation mesh belt is fixed on the organism by penetrating through the pelvic floor fascia on two sides of the organism, so that the flexible magnetic control inclusion body is stably sleeved on the bladder of the organism.
Referring to the attached drawings 1-3, the thermoplastic forming mold of the implanted flexible magnetic control bladder pump comprises: the mold core comprises a mold core 5, a front mold box 1, a rear mold box 2, a front mold box insert block group 3 and a rear mold box insert block 4, wherein referring to figures 8 and 9, the mold core 5 consists of a mold core main body 51 and a mold core handle 52, and the mold core handle 52 is in inserted sliding connection with the mold core main body 51; the shape of the core main body 51 is adapted to the shape of the inflated bladder, and the shape of the core handle 52 is adapted to the shape of the urethra connecting the bladder; the position of the core main body 51 close to the core handle 52 is provided with a bulge 54 which forms a ureter hole 84 and a notch 85 of the implanted flexible magnetic control bladder pump.
The top of the front mould box 1 is provided with a plurality of slots matched with the front mould box plug-in block group 3; a front accommodating chamber is arranged in the front mould box 1; when the core main body 51 is placed in the front mold accommodating chamber, the ferromagnetic complex body positioned at the lower part of the core main body 51 is tightly attached to the inner bottom surface of the front mold box 1; the gap formed after the front mould box 1, the front mould box insert block group 3 and the core main body 51 are assembled is a main body injection molding cavity, and the hot-melt flexible nonmagnetic matrix 82 is injected into the main body injection molding cavity through the slot to form the main body part of the flexible magnetic control inclusion.
The top of the back molding box 2 is provided with a jack matched with the back molding box insert block 4; a rear accommodating chamber is arranged in the rear molding box 2; the mandrel shank 52 is placed in the back-type containment chamber; the gap formed after the rear molding box 2, the rear molding box insert 4 and the core handle 52 are assembled is a urethra injection molding cavity, and the flexible nonmagnetic matrix 82 in a hot melting state is injected into the urethra injection molding cavity through the insertion hole to form a urethra coating body 83 of the flexible magnetic control coating body.
Further, referring to fig. 4 to 7, the front mold 1 includes: the structure comprises a front type box bottom layer structure 11, a front end structure body 12 at the front middle layer of the front type box, a first structure body 13 at the rear end of the middle layer of the front type box, a second structure body 14 at the rear end of the middle layer of the front type box and a front type box top layer structure body 15, wherein the top surface of the front type box bottom layer structure body 11 is matched with the bottom surface of the implanted flexible magnetic control bladder pump in shape; the front molding box middle layer front end structure body 12 is arranged at the upper front end of the front molding box bottom layer structure body 11 in a sliding mode; the front end of the middle layer front end structure body 12 of the front mould box is provided with a positioning slide bar, and the bottom layer structure body 11 of the front mould box is provided with a positioning slide groove corresponding to the positioning slide bar. The positioning slide rod is a U-shaped rod with different rod lengths, the short rod end is fixed at the front end of the middle-layer front-end structural body 12 of the front molding box, and the long rod end extends into the positioning sliding groove. The sliding structure of the front mould box middle layer structure body 12 and the front mould box bottom layer structure body 11 is beneficial to the operation process of placing the core main body 51 in the front mould box 1.
The first structure body 13 at the rear end of the middle layer of the front mould box is movably arranged at the rear end of the left side above the bottom structure body 11 of the front mould box, and the first structure body 13 at the rear end of the middle layer of the front mould box is hinged with the bottom structure body 11 of the front mould box; the front mould box middle layer rear end second structural body 14 is movably arranged at the right side rear end above the front mould box bottom structural body 11, and the front mould box middle layer rear end second structural body 14 is hinged with the front mould box bottom structural body 11. The first structure body 13 at the middle rear end of the front molding box and the second structure body 14 at the middle rear end of the front molding box are respectively provided with two ends in a hinged mode, so that on one hand, the assembly of the mold core 5 is facilitated, and on the other hand, the clamping and fixing of the surgical mesh belt are facilitated.
The front mould top layer structure 15 is hinged on the front mould middle layer front end structure 12, and after the front mould top layer structure 15 is covered on the front mould middle layer front end structure 12, the bulge 54 on the core main body 51 for forming the ureter hole 84 and the notch 85 is tightly attached to the inner wall of the front mould top layer structure 15. The core body 51 forms a body injection molding cavity after being assembled with the front mold box bottom layer structure body 11, the front mold box middle layer front end structure body 12, the front mold box middle layer rear end first structure body 13, the front mold box middle layer rear end second structure body 14, the front mold box top layer structure body 15 and the front mold box insert block group 3.
The bottom shape of the front mould box top structure 15 is matched with the arrangement shape of the ferromagnetic complex on the upper part of the core main body 51; after the front box top layer structure body 15 is turned over to be right above the front box middle layer front end structure body 12, the bottom surface of the front box top layer structure body 15 is attached to the top surfaces of all the ferromagnetic complex bodies, and the positions of the slots correspond to the gap positions of the ferromagnetic complex bodies respectively, namely a plurality of first magnetic strips 811 which are just attached to the ferromagnetic complex bodies on the bottom surface of the front box top layer structure body 15, and the distance between every two adjacent first magnetic strips 811 corresponds to the positions of the slots.
Further, the front mould box 1 further comprises a first net belt limiting group 17 and a second net belt limiting group 16, wherein the first net belt limiting group 17 comprises two first net belt limiting frames which are respectively arranged at the left side and the right side of the front mould box bottom structure body 11; when the main body part of the flexible magnetic control inclusion body is manufactured, one ends of the two first operation net belts 62 penetrate through the corresponding first net belt limiting frames and then are introduced into the main body injection molding cavity, and then the two first operation net belts 62 are clamped and fixed.
The second mesh belt limiting group 16 comprises two second mesh belt limiting frames which are respectively arranged on the first structural body 13 at the rear end of the middle layer of the front molding box and the second structural body 14 at the rear end of the middle layer of the front molding box; when the main body part of the flexible magnetic control inclusion is manufactured, one ends of two second operation mesh belts 61 are led into a main body injection molding cavity after passing through corresponding second mesh belt limiting frames; then, the two second surgical mesh belts 61 are clamped and fixed.
And two third surgical mesh belts 63, one end of which is led into the main body injection molding cavity and the other end of which is led out of the front molding box 1. The front mould box middle layer front end structural body 12 slides to a working position, after the front mould box middle layer rear end first structural body 13 and the front mould box middle layer rear end second structural body 14 are turned over to the front mould box bottom structural body 11, the third operation net belt 63 can be clamped and fixed at the butt joint position of the front mould box middle layer front end structural body 12 and the front mould box middle layer rear end first structural body 13 or the front mould box middle layer rear end second structural body 14, and then the positioning and the fixing of the third operation net belt 63 are realized.
After the three groups of operation net belts are fixed, the hot-melt flexible non-magnetic matrix 82 is injected into the injection molding cavity of the main body, and finally the flexible magnetic control inclusion with the three groups of operation net belts is formed.
Binding lugs 71 extend outwards from two sides of the front mould box bottom layer structure body 11, the front mould box middle layer front end structure body 12 and the front mould box top layer structure body 15 respectively, and after the mould core main body 51 is placed in a front mould accommodating cavity of the front mould box 1, the two binding clamp hoops 72 are fixedly sleeved on the binding lugs 71 on each side respectively, so that the front mould box bottom layer structure body 11, the front mould box middle layer front end structure body 12 and the front mould box top layer structure body 15 are fixed into a whole.
Further, the back mold 2 includes: the mould comprises a rear mould box bottom structure body 21, two rear mould box middle structure bodies 22, a rear mould box top structure body 23 and a rear cover 24, wherein the rear mould box bottom structure body 21 is provided with a rear accommodating chamber for placing a mould core handle 52; the butt joint surface of the rear molding box bottom layer structure body 21 and the front molding box 1 is respectively provided with a positioning lug and a positioning groove 26 matched with the positioning lug.
The two rear molding box middle layer structural bodies 22 are respectively arranged at two sides above the rear molding box bottom layer structural body 21; the butt joint surfaces of the rear molding box middle layer structure 22 and the rear molding box bottom layer structure 21 are respectively provided with a positioning lug 25 and a positioning groove matched with the positioning lug 25.
The rear molding box top layer structure 23 is arranged above the two rear molding box middle layer structures 22, and the butt joint surfaces of the rear molding box top layer structure 23 and the rear molding box middle layer structure 22 are respectively provided with a positioning lug 25 and a positioning groove matched with the positioning lug 25.
The rear cover 24 is arranged at the rear end of the rear molding box bottom structure body 21, and the butt joint surface of the rear cover 24 and the rear molding box bottom structure body 21 is respectively provided with a positioning lug and a positioning groove 26 matched with the positioning lug; the rear cover 24 is attached to the rear end surfaces of the rear box substructure 21, the two rear box mid-layer structures 22, and the rear box top-layer structure 23 after being assembled.
The core handle 52 forms a urethra injection molding cavity after being assembled with the rear molding box bottom structure 21, the two rear molding box middle structures 22, the rear molding box top structure 23, the rear cover 24 and the rear molding box insert 4.
Furthermore, the two sides of the rear molding box bottom structure 21, the two rear molding box middle structure 22 and the rear molding box top structure 23 are respectively extended outward with a binding convex block 71, after the mold core handle 52 is placed in the rear accommodating chamber of the rear molding box 2, the two binding convex blocks 71 on each side are respectively sleeved and fixed by two binding hoops 72, and the rear molding box bottom structure 21, the two rear molding box middle structure 22 and the rear molding box top structure 23 are fixed into a whole.
Binding convex blocks extend outwards from the corresponding positions of the two side ends of the rear molding box bottom structure body 21 and the side end of the front molding box 1 respectively, and the two binding clamp hoops are fixedly sleeved on the binding convex blocks on each side respectively to fix the front molding box 1 and the rear molding box bottom structure body 21 into a whole.
Binding convex blocks extend outwards from the outer side end of the rear molding box middle layer structure body 22 and the corresponding positions of the side end of the front molding box 1 respectively, and are fixedly sleeved on the binding convex blocks on each side through two binding clamp hoops respectively so as to fix the front molding box 1 and the rear molding box middle layer structure body 22 into a whole.
Binding convex blocks extend outwards from the corresponding positions of the two side ends of the rear molding box top layer structure body 23 and the side end of the front molding box 1 respectively, and the binding convex blocks are fixedly sleeved on each side through two binding clamp rings to fix the front molding box 1 and the rear molding box top layer structure body 23 into a whole.
Further, referring to fig. 8 and 9, a slide shaft 53 with a positioning key extends from the center of the end of the core main body 51; the center of the core handle 52 is provided with a shaft hole corresponding to the sliding shaft 53; the core shank 52 is fitted over the slide shaft 53, and when the core 5 is assembled, the core shank 52 is slid to a position where it abuts against the end face of the core main body 51. The positioning key is provided to restrict the rotation of the mandrel shank 52 relative to the slide shaft 53. The slide type core shank 52 is designed to be well fitted to the assembly of the core 5, the core main body 51 is placed on the front mold box 1, the core shank 52 is placed on the rear mold box 2, and then the front mold box 1 and the rear mold box 3 are butted into a whole from a separated state, in which process the core shank 52 slides on the slide shaft 53.
Further, when the implantable flexible magnetically controlled bladder pump is manufactured, the ferromagnetic composite is fixed on the surface of the core main body 51 at a set position by sticking the medical mesh 55. The middle position of the ferromagnetic complex body along the thickness direction is cut open the mesh opening; the medical mesh 55 is stuck on the surface of the core 5 through glue after passing through the split mesh opening; the ferromagnetic complex at the mesh opening is bonded with the medical mesh 55 by glue.
The thermoplastic forming die of the implanted flexible magnetic control bladder pump consists of a core 5, a front mould box 1, a rear mould box 2, a front mould box insert block group 3 and a rear mould box insert block 4; the gap formed after the front mould box 1, the front mould box insert block group 3 and the core main body 51 are assembled is a main body injection molding cavity, and the hot-melt flexible nonmagnetic matrix 82 is injected into the main body injection molding cavity through the slot to form a main body part of a flexible magnetic control inclusion; gaps formed after the rear molding box 2, the rear molding box insert block 4 and the core handle 52 are assembled are a urethra injection molding cavity, the hot-melt flexible non-magnetic matrix 82 is injected into the urethra injection molding cavity through the insertion holes to form a urethra coating body 83 of the flexible magnetic control coating body, so that the implanted flexible magnetic control bladder pump conformal to the filled bladder is successfully manufactured, the manufactured flexible magnetic control bladder pump is sleeved on the neurogenic bladder, the flexible magnetic control bladder pump is enabled to conduct contact type extrusion to empty the bladder, and then the urination function of the disabled bladder is rebuilt.
After the flexible magnetic control bladder pump is implanted into a patient through an operation, the function of normal urination can be realized through the large moment of magnetic force exerted by an external magnetic field under the condition of not connecting any extra external pipeline. The control of the magnetic field does not bring additional harm to the body of the patient, and can provide larger torque; meanwhile, the implanted part is made of light and thin soft material without redundant parts and is directly sewed on the outer surface of the bladder, so that foreign body sensation and sliding cannot be generated, and discomfort is caused; the adopted flexible non-magnetic substrate is a high polymer material with good biocompatibility, and the health of a user is not influenced; due to the structural design of the centripetal movement tendency and the flexibility of the magnetic domain distribution design of the hard magnetic particles, the requirements of different patients can be met, and the effect of completely emptying urine is achieved; because the implanted flexible magnetic control bladder pump does not need to be supplied with energy internally, the implanted flexible magnetic control bladder pump can be permanently placed in a patient body after an operation, so that the implanted flexible magnetic control bladder pump can be used for a whole life after being implanted once, and the economic burden of a patient and the risk of the operation are reduced.
This mould is moulded to heat adopts modular integrated configuration to be convenient for manufacturing, and the structure is exquisite, and the dismouting is simple to be convenient for maintain and change parts, and the simple operation during the use has guaranteed higher moulding manufacturing efficiency of heat.
The above-mentioned embodiments, objects, technical solutions and advantages of the present invention are further described in detail, it should be understood that the above-mentioned embodiments are only illustrative of the present invention and are not intended to limit the present invention, and any modifications, equivalents, improvements and the like made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. The thermoplastic forming die of the implanted flexible magnetic control bladder pump is characterized in that the implanted flexible magnetic control bladder pump is a flexible magnetic control inclusion formed by combining a flexible non-magnetic base body and a ferromagnetic complex; the implanted flexible magnetic control bladder pump is adapted to the shape of the inflated bladder, and a movable cavity wrapping the bladder is arranged in the implanted flexible magnetic control bladder pump; the thermoplastic forming die comprises: a core, a front molding box, a rear molding box, a front molding box insert block group and a rear molding box insert block, wherein,
the mold core consists of a mold core main body and a mold core handle, and the mold core handle is in inserted sliding connection with the mold core main body; the shape of the core main body is adapted to the shape of the inflated bladder, and the shape of the core handle is adapted to the shape of the urethra connected with the bladder; the position of the core body close to the core handle is provided with a bulge for forming a ureteral orifice and a cut of the implanted flexible magnetic control bladder pump;
the top of the front mould box is provided with a plurality of slots matched with the front mould box plug block group; a front accommodating chamber is arranged in the front molding box; when the core main body is placed in the front mould accommodating cavity, the ferromagnetic complex body positioned at the lower part of the core main body is tightly attached to the inner bottom surface of the front mould box; the gap formed after the front mould box, the front mould box insert block group and the core main body are assembled is a main body injection molding cavity, and the flexible nonmagnetic matrix in a hot melting state is injected into the main body injection molding cavity through the slot to form a main body part of the flexible magnetic control inclusion;
the top of the rear molding box is provided with a jack matched with the rear molding box insert block; a rear accommodating chamber is arranged in the rear molding box; the core handle is arranged in the back mold accommodating cavity; the gap formed after the rear mould box, the rear mould box insert block and the core handle are assembled is a urethra injection molding cavity, and the flexible non-magnetic matrix in a hot melting state is injected into the urethra injection molding cavity through the insertion hole to form a urethra coating body of the flexible magnetic control coating body.
2. The thermoplastic molding mold for an implantable flexible magnetically controlled bladder pump according to claim 1, wherein the anterior mold box comprises: a front-type box bottom layer structure body, a front-type box middle layer front end structure body, a front-type box middle layer rear end first structure body, a front-type box middle layer rear end second structure body and a front-type box top layer structure body, wherein,
the top surface of the front mould box bottom layer structure body is matched with the bottom surface of the implanted flexible magnetic control bladder pump in shape;
the front mould box middle layer front end structure body is arranged at the front end above the front mould box bottom layer structure body in a sliding manner; a positioning slide rod is arranged at the front end of the front structure body in the middle layer of the front mould box, and a positioning slide groove is arranged in the front structure body at the bottom layer of the front mould box corresponding to the positioning slide rod;
the first structure body at the rear end of the middle layer of the front mould box is movably arranged at the rear end of the left side above the structure body at the bottom layer of the front mould box, and the first structure body at the rear end of the middle layer of the front mould box is hinged with the structure body at the bottom layer of the front mould box;
the second structure body at the rear end of the middle layer of the front mould box is movably arranged at the rear end of the right side above the structure body at the bottom layer of the front mould box, and the second structure body at the rear end of the middle layer of the front mould box is hinged with the structure body at the bottom layer of the front mould box;
the front mould box top structure body is hinged on the front end structure body of the front mould box middle layer;
the core main body and the front mould box bottom layer structure body, the front mould box middle layer front end structure body, the front mould box middle layer rear end first structure body, the front mould box middle layer rear end second structure body, the front mould box top layer structure body and the front mould box plug block group are assembled to form the main body injection molding cavity.
3. The thermoplastic molding mold of an implantable flexible magnetically controlled bladder pump according to claim 2,
the bottom surface shape of the front mould box top layer structure body is matched with the arrangement shape of the ferromagnetic complex on the upper part of the core main body; and after the front molding box top structure body is turned over to be right above the front molding box middle layer front end structure body, the bottom surface of the front molding box top structure body is attached to the top surfaces of all the ferromagnetic complex bodies, and the positions of the slots respectively correspond to the gap positions of the ferromagnetic complex bodies.
4. The thermoplastic molding mold for an implantable flexible magnetically controlled bladder pump of claim 2, wherein the former block further comprises a first belt set and a second belt set,
the first mesh belt limiting group comprises two first mesh belt limiting frames which are respectively arranged on the left side and the right side of the front mould box bottom layer structure body; when the main body part of the flexible magnetic control inclusion body is manufactured, one ends of two first operation mesh belts pass through the corresponding first mesh belt limiting frames and then are introduced into the main body injection molding cavity;
the second mesh belt limiting group comprises two second mesh belt limiting frames which are respectively arranged on the first structural body at the rear end of the middle layer of the front molding box and the second structural body at the rear end of the middle layer of the front molding box; and when the main body part of the flexible magnetic control inclusion body is manufactured, one ends of two second operation mesh belts pass through the corresponding second mesh belt limiting frames and then are introduced into the main body injection molding cavity.
5. The mold for thermoplastic molding of an implantable flexible magnetically controlled bladder pump according to claim 2, wherein the bottom front mold structure, the middle front mold structure and the top front mold structure have outward extending binding protrusions, respectively, and the core body is placed in the front receiving cavity of the front mold and then fixed to the binding protrusions of each side by two binding clips, respectively, to fix the bottom front mold structure, the middle front mold structure and the top front mold structure integrally.
6. The thermoforming mold of an implantable flexible magnetically controlled bladder pump according to claim 1, wherein the back mold comprises: a back molding box bottom layer structure body, two back molding box middle layer structure bodies, a back molding box top layer structure body and a back cover, wherein,
the rear mould box bottom structure is provided with a rear mould accommodating chamber for placing the mould core handle; the butt joint surface of the rear molding box bottom structure body and the front molding box is respectively provided with a positioning lug and a positioning groove matched with the positioning lug;
the two rear molding box middle layer structural bodies are respectively arranged at two sides above the rear molding box bottom layer structural body; the butt joint surface of the rear molding box middle layer structure body and the rear molding box bottom layer structure body is respectively provided with a positioning lug and a positioning groove matched with the positioning lug;
the rear molding box top layer structure body is arranged above the two rear molding box middle layer structure bodies, and the butt joint surfaces of the rear molding box top layer structure body and the rear molding box middle layer structure body are respectively provided with a positioning lug and a positioning groove matched with the positioning lug;
the rear cover is arranged at the rear end of the rear molding box bottom structure body, and a positioning lug and a positioning groove matched with the positioning lug are respectively arranged on the butt joint surface of the rear cover and the rear molding box bottom structure body; the rear cover is assembled and then clings to the rear end surfaces of the rear molding box bottom structure body, the two rear molding box middle structure bodies and the rear molding box top structure body;
the core handle, the back mould box bottom structure, the two back mould box middle structure, the back mould box top structure, the back cover and the back mould box insert block are assembled to form the urethra injection molding cavity.
7. The thermoplastic molding mold for an implantable flexible magnetically controlled bladder pump according to claim 6,
binding lugs extend outwards from two sides of the rear molding box bottom structure body, the two rear molding box middle structure bodies and the rear molding box top structure body respectively, and the core handles are placed in the rear accommodating cavity of the rear molding box and are fixedly sleeved on the binding lugs on each side through two binding hoops respectively so as to fix the rear molding box bottom structure body, the two rear molding box middle structure bodies and the rear molding box top structure body into a whole;
binding convex blocks extend outwards from the corresponding positions of the two side ends of the rear molding box bottom structure and the side end of the front molding box respectively, and are fixedly sleeved on the binding convex blocks on each side through two binding clamp rings respectively so as to fix the front molding box and the rear molding box bottom structure into a whole;
binding convex blocks extend outwards from the outer side end of the middle layer structure of the rear molding box and the corresponding positions of the side end of the front molding box respectively, and are fixedly sleeved on the binding convex blocks on each side through two binding clamp hoops respectively so as to fix the front molding box and the middle layer structure of the rear molding box into a whole;
and binding convex blocks extend outwards from the corresponding positions of the two side ends of the rear molding box top layer structure body and the side end of the front molding box respectively, and are fixedly sleeved on the binding convex blocks on each side through two binding clamp rings respectively so as to fix the front molding box and the rear molding box top layer structure body into a whole.
8. The thermoplastic molding die for the implantable flexible magnetically controlled bladder pump according to claim 1, wherein a slide shaft with a positioning key extends from the center of the end of the core body; the center of the core handle is provided with a shaft hole corresponding to the sliding shaft; the core handle is sleeved on the sliding shaft, and the core handle is slid to a position attached to the end face of the core main body when the core is assembled.
9. The thermoplastic molding die for the implantable flexible magnetically controlled bladder pump according to claim 1, wherein the ferromagnetic composite body is fixed on the surface of the core body at a set position by medical mesh bonding during manufacturing of the implantable flexible magnetically controlled bladder pump.
10. The thermoplastic molding die of the implanted flexible magnetically controlled bladder pump according to claim 9, wherein the ferromagnetic composite body is split at a middle position in the thickness direction through a mesh opening; the medical mesh passes through the split mesh opening and is adhered to the surface of the mold core through glue; the ferromagnetic complex at the mesh opening is bonded with the medical mesh by glue.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110163986.4A CN112810046A (en) | 2021-02-05 | 2021-02-05 | Thermoplastic forming die of implanted flexible magnetic control bladder pump |
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| CN202110163986.4A CN112810046A (en) | 2021-02-05 | 2021-02-05 | Thermoplastic forming die of implanted flexible magnetic control bladder pump |
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| CN112810046A true CN112810046A (en) | 2021-05-18 |
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| CN113648104A (en) * | 2021-08-18 | 2021-11-16 | 华中科技大学同济医学院附属同济医院 | Implanted flexible magnetic control bladder extrusion device |
| CN113910549A (en) * | 2021-10-11 | 2022-01-11 | 四川大学华西医院 | Thermoplastic forming die of implanted flexible magnetic control bladder pump |
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