CN112790125A - Creation method of rabbit hundred-pleated skirt Taishi goldfish - Google Patents

Creation method of rabbit hundred-pleated skirt Taishi goldfish Download PDF

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CN112790125A
CN112790125A CN202110089143.4A CN202110089143A CN112790125A CN 112790125 A CN112790125 A CN 112790125A CN 202110089143 A CN202110089143 A CN 202110089143A CN 112790125 A CN112790125 A CN 112790125A
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余鹏
桂建芳
汪洋
周莉
李志�
李亮亮
杨小丽
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Institute of Hydrobiology of CAS
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Abstract

The invention relates to a fish molecular design breeding technology, in particular to a method for creating a rabbit hundred-pleated skirt Tai lion goldfish. The method comprises the steps of target point design, microinjection and fertilization incubation. The invention is based on CRISPR/Cas9 gene editing technology, the rabbit goldfish with red-eye characteristic is generated on F0 generation goldfish after knockout is carried out on pigment gene oca2, the high-efficiency gynogenesis condition and high-temperature group expanding condition of the golden fish of the ruffle skirt Taishi are established through experiments, and the homozygote of the golden fish of the Yurabbit ruffle skirt Taishi is obtained in F1 generation; and extensive population expansion was carried out for the F2 generation by temperature-induced reversal. The invention quickly realizes the transfer of single target characters by a molecular breeding means, stably and quickly creates a variety of the rabbit hundred-pleated lion Tai-Goldfish with high ornamental value, and has wide application prospect and market value.

Description

Creation method of rabbit hundred-pleated skirt Taishi goldfish
Technical Field
The invention relates to a fish molecular design breeding technology, in particular to a method for creating a rabbit hundred-pleated skirt Tai lion goldfish.
Technical Field
The goldfish is originated from tetraploid crucian carps in China, is an ornamental fish formed by artificial selection for hundreds of years, and is named as Chinese essence in China. In the development history of goldfishes, the body color, body type and almost all external organs of the goldfishes are obviously changed due to mutation, the mutation is reserved under the action of artificial selection, and then the mutation is recombined through hybridization to form a plurality of goldfishes with complex variation; nowadays, goldfish have more than 300 varieties.
The color is an important direction for future breeding of the goldfish, and the good-looking color system can greatly increase the ornamental value of the goldfish, such as tiger stripes, ink and wash, dairy cow color systems and the like. In goldfish, there is a phenomenon of yellowing or whitening, which is manifested as white or yellowish color of the whole body, and the eye becomes transparent red, and is called a rabbit like rabbit. Previous reports of this goldfish appeared only on a very small variety of goldfish of normal scales, which showed a delicate ornamental feature but were almost vacant in the market. Although many fisheries are trying, the fish body color can be purified to white at most, the eyes are still black, and the fish is not yellowed/whitened in the true sense, so the real rabbit goldfish does not appear.
If a few individual varieties of the rabbit goldfishes exist, the characters of the rabbits are transferred to the variety of the hundred-skirt Tai lion goldfishes, and only a method of continuous purification after hybridization is available at present. However, the hybridization can weaken and even lose many original characters of the target fish, and the transfer of single target characters cannot be realized.
How to stably obtain the hundred-pleated-skirt Taishi goldfish which has a rabbit-shaped appearance and still retains other ornamental values is an unsolved problem.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a method for creating a rabbit and hundred-pleated skirt lion-Tai goldfish.
The invention adopts the following technical scheme:
a method for creating germplasm of a hundred-pleated skirt Tai lion goldfish comprises the following steps:
s1, target point design: carrying out gene sequencing on the golden fish of the Bairuu Taishi to obtain a DNA sequence of a gene for regulating and controlling the properties of the rabbit, designing a proper knockout target spot on an exon of the DNA sequence, and transcribing the sequence of the target spot into gRNA in vitro;
the rabbit character gene is pigment gene oca2, and the DNA sequence and amino acid sequence of the gene are shown in the sequence list part of the specification;
the sequence of the target point is as follows: GGAGTATATTCTGATCCAGG are provided.
S2, microinjection: flatly paving roes of the golden fish of the Bairuu Taishi in a sterile culture dish, adding a proper amount of ovarian fluid, taking 2 mu L of each mRNA of CRISPR/Cas9 protein and gRNA, uniformly mixing, injecting the mixed mRNA into an egg animal pole by using a microinjection instrument, and injecting 200-grain roes and 3000-grain roes into 4 mu L of the uniformly mixed mRNA;
s3, fertilization and incubation: and adding the sperms of the male plenopus heterophyllus into a culture dish after the injection operation is finished, transferring fertilized eggs to an incubation nest for incubation after the fish eggs are fertilized, and obtaining the plenopus heterophyllus goldfish with the characteristics of a jade rabbit.
Preferably, the method further comprises a step of gynogenesis, wherein the gynogenesis method comprises the following steps: taking the golden fish of the Bai-Shi-Tai lion with the rabbit phenotype in the S3 as a parent, namely an F0 generation, taking carp sperms for inactivation, mixing inactivated semen and the eggs of the female Bai-Shi-Tai lion golden fish of the F0 generation for fertilization, then carrying out shock treatment, and hatching the fertilized eggs to obtain the F1 generation homozygous golden fish of the Bai-Shi-Tai lion with the rabbit trait.
Preferably, the method also comprises a high-temperature group expanding step, wherein the high-temperature group expanding method comprises the steps of feeding part of female fish at the high temperature of 27-28 ℃ at the early stage after the F1 generation homozygote is subjected to membrane emergence, so that the female fish is subjected to sex reversal to be male fish, the sex reversal female fish and the normally fed F1 generation female fish are bred, and the homozygote offspring baotia populi Tai goldfish is obtained in batches.
Preferably, in the step S1, the exon and the intron of the gene for regulating and controlling the rabbit character are designed and obtained according to the DNA sequence of the obtained gene, and a knockout target point is designed on the exon sequence of the Baikui Taishi goldfish oca2 gene by using GG [ G/A ] GG or CC [ T/C ] CC wildcard.
Preferably, in step S1, after obtaining the target sequence, before in vitro transcription, a local genome database is constructed using the target sequence, and the uniqueness of the target is searched and determined using blast software.
Preferably, in step S3, before hatching the fertilized eggs, the method further includes a knockout efficiency detection operation, wherein 10 fertilized eggs before emergence of the membrane are randomly selected, DNA in the fertilized eggs is extracted as a template, DNA sequences near the knockout target are amplified and sequenced and compared with normal sequences, the knockout efficiency is calculated according to the comparison result, if the knockout efficiency reaches 20% or more, the fertilized eggs in the group are kept for continuous hatching, otherwise, hatching is terminated and knockout is performed again, mRNA injection concentrations of CRISPR/Cas9 and gRNA are knocked out again, or the target sequences are injected again after in vitro transcription.
Preferably, the extracting DNA from fertilized eggs and the amplifying are specifically: putting the selected fertilized eggs into a PCR tube, adding 70-100 mu L of 50mM NaOH solution, reacting in a PCR instrument at 95 ℃ for 20min, and taking the mixture as a DNA template; designing a PCR amplification primer near a knockout target, selecting 10 target clones after PCR amplification, transformation and cloning, sequencing and comparing with a normal sequence to check whether the knockout site is knocked out, wherein the region near the target is 200-300bp upstream and downstream of the target.
Preferably, the goldfish ovum for gynogenesis is taken from the same F0 generation female golden marmot of Bairuyi Thailand lion.
Preferably, in step S2, after the fertilized eggs are hatched to form fry, the temperature of the raising water for fry is not more than 24 ℃ within 1 month of hatching.
Preferably, the shock treatment is heat shock, and the fertilized eggs are placed in water at 41 ℃ for heat shock treatment for 2min after being developed at the constant temperature of 24 ℃ for 43-47 min.
Preferably, the shock treatment is cold shock, and the fertilized eggs are placed in ice water at 0 ℃ for cold shock for 2min after being developed at a constant temperature of 24 ℃ for 3-7 min.
The invention has the beneficial effects that:
1. since the gold fish of the Lyophyllum decastes is tetraploid, and the chromosomes are doubled compared with those of the diploid, many genes are two in the gold fish, which are respectively called a and b. The oca2 gene used in the invention is two in the Bairuu Taishi goldfish, which are respectively named as oca2a and oca2B, and when a and B are required to be knocked out simultaneously in order to knock out oca2 gene, the knock-out in the prior art is usually to design a specific target point of A and then design a target point of B, and knock out A and B after combination, but the effect of only one target point is sometimes generated, so that the purpose of completely knocking out the gene cannot be achieved, and therefore, the desired phenotype cannot be obtained, and the knock-out fails. The invention only designs 1 target spot, and can successfully knock out 2 genes by using only one target spot to generate effect, generate required phenotype, and is efficient, convenient and fast.
2. The invention inseminates after injecting fish eggs, so that RNA is translated into protein in advance to generate effect, and the gene editing efficiency is improved. The injection is carried out on the fish eggs with weak viscosity, and the phenomenon that the injection needle is blocked by the viscosity generated after the fish eggs are fertilized is effectively avoided, so that the microinjection is successfully carried out. In addition, the injection concentration of mRNA of CRISPR/Cas9 protein (400-600 ng/. mu.L) and gRNA (150-300 ng/. mu.L) is improved, so that the knockout efficiency can be effectively increased. The technology realizes F0 generation to obtain a great amount of chimeric goldfishes with rabbit characters.
3. The invention obtains the nucleotide and amino acid sequence of the goldfish oca2 gene by whole genome sequencing. The method is matched with a goldfish efficient propagation technology to provide high-quality roe for gene knockout of goldfishes and provide necessary experimental materials for exploration of gynogenesis conditions; the invention can reduce background difference by using multiple spawning experiments of the same fish, and is beneficial to exploring the optimal conditions for gynogenesis.
4. Meanwhile, the invention obtains homozygous fish in F1 generation by an artificial gynogenesis method; the fish sex of the gynogenesis is reversed into a male fish by a high-temperature stimulation method, and then the male fish is fertilized with a normal F1 female fish, and the Baikui Taishi with the rabbit character is obtained in batches by the F2 generation. The establishment of a series of methods with challenge on goldfish and the combination of the methods enable the molecular design breeding technology to be applied to goldfish for the first time, successfully realize the transfer of single-purpose characters, and successfully transfer the characteristics of the rabbit to the golden fish of the Bairuyi Taishi lion without changing other ornamental characters, thereby successfully creating a new variety of the golden fish of the Yutu Bairuyi Taishi lion with extremely high ornamental value. The method also provides technical support for the efficient cultivation of new goldfish varieties by molecular design breeding.
Drawings
FIG. 1 is a normal ruffle lion goldfish;
FIG. 2 is a schematic view of a Jade rabbit-shaped Bai-shirt Tai lion goldfish, which shows that the eyes and body color of the Jade rabbit-shirt Tai lion goldfish are lighter, and the ornamental characters in the aspects of head tumor, dorsal fin, tail, body type and the like are consistent with those of the Bai-shirt Tai lion goldfish with normal body color and are not lost;
FIG. 3 is a color photograph of the normal baypu lion goldfish of FIG. 1;
FIG. 4 is a color photograph of the rabbit-shaped Baizu Taishi goldfish shown in FIG. 2, wherein the body color of the rabbit-shaped Baizu Taishi goldfish appears white to light yellow, and the eyes become transparent red.
Detailed Description
For easy understanding, the technical solution of the present invention is described in more detail with reference to the following embodiments:
example 1: efficient breeding of golden fish of Bairuu Taishi
S1, seedling cultivation: feeding newly opened fry in a turnover box at 23-25 deg.C for 3 times a day, wherein the turnover box has a length of 60-100cm, a width of 40-60cm, a height of 20-30cm, and a water level of 15-20 cm. One side of the turnover box is provided with a sponge filter for filtration, and an oxygen increasing head is arranged beside the turnover box for oxygenation, and the oxygen amount is appropriate. The sponge filter was cleaned once a week.
After the body length of the fry exceeds 2cm, selecting four fries in a overlooking mode, removing the fries with deformed and folded fin lines in a side view, and feeding the selected high-quality fries in a new container with the density of about 2 fishes per liter of water; the container is internally provided with a 7-watt small-sized water pump for dripping and adding water, the daily water inflow is 1/5 of the total water body, and the three layers of turnover box dripping boxes are used for filtering. The fairy shrimp is fed manually for 1 time every day, the automatic feeder feeds the fodder with 48 percent of protein content for 5 times, and the feeding amount is preferably 10min for each time. The first layer of the circulation box is provided with a filter pad material such as a magic blanket and filter cotton, the second layer and the third layer are provided with bacterial balls, liquid digestive live bacteria are added on the day of fry placement to help fries to quickly establish a digestive system, and the adding amount is 100mL of liquid digestive live bacteria added in every 100L of water. The magic blanket is a filtering blanket with long fluff on one side, and can be cleaned repeatedly.
When the length of the fry exceeds 4cm, the fry with longer body length, stout body, back peak, upwarping tail and round and moist tail tip is selected and put into a fish tank, the length of the fish tank is more than 80cm, the width of the fish tank is more than 50cm, the water depth is preferably 30-40cm, and the density is 1 fish per liter of water. And continuously filtering by using a drop box of a turnover box, adjusting the hourly flow of a water pump to be 3-5 times of the total water body, feeding the feed with 46 percent of protein for 5 times every day by using an automatic feeder, wherein the feeding amount is suitable for 5min to finish feeding every time, and meanwhile, manually feeding Chironomus larvae at noon and evening, wherein the feeding amount is 15min to finish feeding.
When the body length of a fry exceeds 8cm, selecting a fish with strong and uniform body, round and upwarping tail and ruffles, putting the fish into a fish tank, wherein the fish tank is over 80cm long, 50-60 cm wide and 40-50 cm deep in water, feeding the feed with 46% of protein content for 5 times by an automatic feeder every day, feeding the feed for 10min each time, feeding the shrimps to supplement calcium at noon, feeding the midnight midge larvae to increase bodies, and feeding the midge larvae for 15 min. Irradiating the fish tank with lamp light of three-primary-color lamp beads with a lens, wherein the power of the three-primary-color lamp beads is 80w, the lamp-on time is 7: 30-24: 00, and the green algae are attached to the bottom of the fish tank and fully spread to form a moss shape through the lamp light irradiation.
S2, parent cultivation: when the fish body is more than 12cm in length, selecting the fish with strong and uniform physique, round and smooth tail and upwarping and with ruffles as a parent, feeding the fish with feed with 44% of protein content 5 times every day, feeding the fish with feed for 5min each time, feeding the fish with brine shrimp for supplementing calcium at noon, and feeding the fish with feed for 15 min.
A bottom filtration system with strong filtration is selected to filter the water body, and water is changed 2-3 times per week when the water temperature is 24-26 ℃ in summer, 1/3 water is changed every time, and water is changed 1-2 times per week when the water temperature is 21-23 ℃ in winter, 1/4-1/3 water is changed every time; when water is added, the dechlorinated tap water is added, or the tap water can be directly added, but the water inlet flow is slow and is controlled to be full in half an hour, and the temperature difference is large in winter, so that the time is prolonged properly. The filter cotton in the filter system is replaced and cleaned when water is replaced, preferably, the filter cotton is replaced at noon in a fine day, the chlorine in tap water can be effectively removed and the water temperature can be improved due to high temperature, and the damage of the temperature difference to the fish is reduced. The filter cotton is cleaned by a high-pressure water gun and then dried in the sun for sterilization.
The method is characterized in that 3 lenses are additionally arranged on an algae exposure lamp or a worm-germinating lamp, algae exposure is started for 12 hours every day, green algae grow on a bottom layer gradually and form a green coating, organic residues such as fish feces and the like in the green coating are cleaned by a brush every two days, the green algae can be used as plant baits to provide rich nutrients such as vitamins and dietary fibers for breeding fishes, and nitrogen, phosphorus and other substances in a water body can be absorbed.
S3, artificial insemination: when the male fish and the female fish with rear-end collision are observed, fishing out the female fish, manually extruding eggs, collecting the eggs at the cloaca by using a 10mL centrifuge tube, adding semen into the centrifuge tube, covering a tube cover, slightly turning upside down to complete the sufficient mixing of the sperm and the eggs, putting the incubation bed into an incubator, controlling the water depth of the incubator to be 10-30cm, controlling the water temperature to be 22-24 ℃, pouring the sufficiently mixed eggs into the incubation bed, uniformly spreading, carrying out oxygen-charging incubation, and preferably using running water for incubation.
The 10mL centrifuge tube is used for collecting roes, all roes are collected conveniently, waste is avoided, the roes cannot be stuck to the goldfish fin, the roes are prevented from being brought back to the fish tank by the fin to pollute water, the roes can be stored in the centrifuge tube at room temperature for half a day, and the experiment is convenient to use. When insemination is needed, semen is directly extruded into a centrifuge tube, or the semen is sucked by a pipette tip and added into the centrifuge tube, a tube cover is covered, and the semen and the roe are mixed by slightly reversing the upper part and the lower part. At the moment, the roes with the semen mixed evenly are poured into a basin and laid out evenly for hatching, and the insemination rate reaches up to 99 percent.
S4, postnatal care: in 3 hours after the goldfish lays eggs, water is changed from the fish tank 1/4 in winter and from the fish tank 1/3 in summer, and the dried clean filter cotton is cleaned and replaced, so that the situation that the water quality is damaged due to breeding of bacteria caused by excessive semen and ovarian fluid in the water body is avoided, and the death of the goldfish after laying is avoided.
During the culture process, salt, baking soda, methylene blue, white-point agent, heating rod and the like are prepared for preventing and treating fish diseases. If the fish is found to be in a bad state, 1/4 g/L water is replaced, salt is added for sterilization, sodium bicarbonate is added in a proper amount to adjust the pH value to 8, and the water temperature is maintained at 25-27 ℃, so that the fish can be quickly recovered.
Example 2: exploration of gynogenesis conditions
Two gynogenesis methods are established, the proportion of normal fish generated by the two methods is compared, and the optimal gynogenesis condition of the Taishi goldfish with high homozygote yield is selected.
1. Meiotic gynogenesis
Inactivating the sperm of the carp, mixing the inactivated sperm with the ovum of the golden fish of the hundred-shire Taishi lion for fertilization, and then carrying out cold shock treatment, wherein the cold shock treatment method comprises the steps of developing the fertilized ovum at the constant temperature of 24 ℃ for 3-7min, and then placing the fertilized ovum in ice water at the temperature of 0 ℃ for cold shock for 2min to inhibit the discharge of a second diode, so that two gametes are combined into a whole to form the tetraploid. Hatching the fertilized eggs after cold shock treatment to obtain the meiosis Taishi goldfish with the characteristics of a rabbit.
2. Mitotic gynogenesis
Inactivating the sperm of the carp, mixing the inactivated sperm with the eggs of the hundred-pleated Taishi goldfish for fertilization, and then carrying out heat shock treatment, wherein the heat shock treatment method comprises the steps of developing the fertilized eggs at the constant temperature of 24 ℃ for 43-47min, and then placing the fertilized eggs in water at the temperature of 41 ℃ for 2min so as to destroy the formation of spindle threads, so that the two steps are combined into one. Hatching the fertilized eggs after heat shock treatment to obtain the mitotic lion goldfish with the characteristics of a rabbit.
The egg of the golden fish of the ruffle tao lion used above is preferably the egg produced from the same ruffle tao golden fish to reduce the background difference.
The fertilization rate, the membrane emergence rate and the normal rate of the tai-shi goldfish generated by meiosis and mitosis are counted, the results are shown in table 1, and as can be seen from table 1, the number of the normal fish obtained by heat shock 47min after fertilization is higher than that of other combinations and reaches 3.34%, and the number of the normal fish obtained by cold shock 6min after fertilization is higher than that of other combinations and reaches 45.52%.
TABLE 1 statistics of F1 generation homozygote under mitotic and meiotic conditions
Figure BDA0002911778820000071
Example 3: creation of rabbit hundred-pleated skirt Taishi goldfish
S1, target point design: performing gene sequencing on the golden fish of the Bairuu Taishi lion to obtain a DNA sequence and an amino acid sequence of a gene for regulating and controlling the rabbit character, designing a proper knockout target on an exon of the DNA sequence of the gene for regulating and controlling the rabbit character by using a wildcard GG [ G/A ] GG or CC; in wildcard "? "represents an arbitrary base," [ ] "represents a match with any one of the bases within [ ],"/"represents an" or ".
The gene for regulating and controlling the rabbit character is oca2 gene, the number of the target points is 1, and the sequence of the target points is as follows:
GGAGTATATTCTGATCCAGG;
s2, microinjection: flatly paving roes of the golden sea bream lion in an aseptic culture dish, adding a proper amount of ovarian liquid to prevent the roes from being dry, taking 2 mu L of each mRNA of CRISPR/Cas9 protein and gRNA, uniformly mixing, injecting the mixed mRNA into an egg animal pole by using a microinjection instrument, and injecting 200-3000 roes into 4 mu L of the mixed mRNA;
s3, fertilization and incubation: and adding male plectrum unijugum and Taishi goldfish sperms into a culture dish after injection operation is completed, transferring fertilized eggs to an incubation nest for incubation after fertilization of the fish eggs, putting 10 fertilized eggs which are just before membrane removal into a PCR (polymerase chain reaction) tube, adding 70-100 mu L of 50mM NaOH solution, and reacting in a PCR instrument at 95 ℃ for 20min to obtain a DNA template. Designing PCR amplification primers near the knockout target, selecting 10 target clones after PCR amplification, transformation and cloning, sequencing, comparing with a normal sequence to check whether the knockout site is knocked out, and calculating the knockout efficiency according to the comparison result.
The specific method for selecting 10 target clones for sequencing after PCR amplification, transformation and cloning comprises the following steps: and performing PCR amplification on DNA sequences near a target by using 10 DNA templates, recovering PCR products, connecting the recovered PCR products to a vector, transforming the vector into competent cells, and selecting 10 positive clones for sequencing after overnight culture at 37 ℃ in an Amp culture medium so as to test whether the knockout site is knocked out.
In this step, "near the target" refers to the 200 and 300bp regions upstream and downstream of the target.
If the fertilized egg rate of the knocked-out target spot reaches 20% or more, the fertilized eggs are kept for further hatching, and the obtained golden fish of the Bairuu Taishi is the golden fish of the Bairuu Taishi with the characteristics of a rabbit. Otherwise, the incubation is terminated, the knockout is carried out again, the mRNA injection concentration of CRISPR/Cas9 and gRNA is increased when the knockout is carried out again, or the steps S2 and S3 are repeated after the target sequence is transcribed in vitro again.
S4, fry feeding and parent selection: after the fertilized eggs are hatched to produce fry, raising the fry to be large, wherein the raising water temperature does not exceed 24 ℃ in the early 1 month, and the eyes begin to bulge outwards when the fry is raised for about 2-3 months, and the obtained plectrum rufimbriae tai golden fish is the chimeric plectrum ruffle golden fish with the character after the target gene is knocked out; select good and eye-bulging Baikui Taishi as parent, and record as generation F0.
S5, gynogenesis: inactivating the sperm of the carp, mixing the inactivated sperm with the ovum of the female plectrum thyesti of Taishi lion of F0 generation for fertilization, and then carrying out cold shock treatment, wherein the cold shock treatment method comprises the steps of developing the fertilized ovum at the constant temperature of 24 ℃ for 3-7min, then placing the fertilized ovum in ice water at the temperature of 0 ℃ for 2min, and hatching the treated fertilized ovum to obtain the homozygous of F1 generation with the characteristics of a rabbit.
S6, high-temperature group expanding: at the early stage after the membrane generation of F1, feeding half of female fish at high temperature of 27-28 deg.C to make female fish become male fish in sex reversal, breeding the female fish in sex reversal and the female fish of F1 generation fed normally to obtain the pure zygote offspring Baikui lion goldfish in batches.
Example 4: creation of rabbit hundred-pleated skirt Taishi goldfish
The preparation method of example 4 is the same as that of example 3, except that in step S5, the fertilized egg is subjected to heat shock treatment, and the specific operations of S5 are as follows:
s5, gynogenesis: inactivating the sperm of the carp, mixing the inactivated sperm with the ovum of the female plectrum thyesti of Taishi lion of F0 generation for fertilization, and then carrying out heat shock treatment, wherein the heat shock treatment method comprises the steps of developing the fertilized ovum at the constant temperature of 24 ℃ for 43-47min, then placing the fertilized ovum in ice water at the temperature of 41 ℃ for 2min, and hatching the treated fertilized ovum to obtain the homozygous of F1 generation with the characteristics of a rabbit.
The above embodiments are only used to illustrate the technical solutions of the present invention, and do not limit the present invention; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those skilled in the art that: any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Figure BDA0002911778820000101
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Sequence listing
<110> institute of aquatic organisms of Chinese academy of sciences
<120> creation method of rabbit hundred-pleated skirt lion goldfish
<141> 2021-01-22
<160> 4
<170> SIPOSequenceListing 1.0
<210> 1
<211> 75568
<212> DNA
<213> Carassius auratus
<400> 1
tgtgttccag ccaagcccga tgtgagttgc gagaaggtag cacatgccta tcgtgcaggt 60
catcagcatc atagggaagc ccaacctgtg aaatagagca cagcaagaat tcatgttatg 120
aagatgaaaa ctgaacttta gaaagtctgt aaatcccatt ctgtcagaag ggagaattca 180
atgtatagct tttggggaaa gaatctgcaa cacagtctga tgcttggtgc tctttcttaa 240
tgaaagactg tatgcttgtg ttccactgaa agttcatctc ccagcattcc cctctgtttc 300
attcctcgtt tgtttctcat atgatgattt ctgagcagtt tcgcattatt ctcccttctg 360
cggagcattt gtttaagtct gtctgtgtgt gtgtgattcg attctgatca gcaggggtct 420
cgatgctctc ctgctgagga gcgtgacagg aacgttaact gcttcatcga cttggtatta 480
aagtgtgagt ctttaaacat tacggcagag tcaaaggcag aggacaaaag cagtaaagta 540
tgatctccag gcattattat tgaagtcaaa ggctggagac gcaataggac tgatgatact 600
tgtcccccca tttaacataa gctgctttcc tcaaagccgt caactctcag agacacatgg 660
accgtacttg ttgtgtttgc ttgtaaaagc atccatctgg agagtggaat taccattgta 720
attacaactg gacactggcc taatctccag actcgatcgg catgaatcag tgcccttttg 780
accctcggtt caacatgctg tgtctcatct gtccatgagg attatactac atgccatcca 840
aactcaaata ttatcagtag aactgcacat ggacactatg tgcagacaca taaatcagta 900
caaaagaaat caacagatta taaagagaag tggacagatt atcaagggaa catggacaat 960
agcacccaga aaatacacag cgaactatat aatctgtttg caaaacaatg tcagtgccca 1020
accctgcctc tatcaaataa tcgagaccaa tataaattag attctgtcat tattaactca 1080
ccccgatgcc atttcaaatc tgtgctttat tttctgtgaa acacacaagg agaattttaa 1140
aacatctata tgtaaatcct gtttcatata acaaagttca aagtgttcat ggctttggga 1200
aaaaatctgg taaaacttta gaataggtaa cacctattag ctgcttatta gcatgcatat 1260
tactagaata ttagctatgt attggtgcta attaaaaaca tattaatgcc ttattctaca 1320
tccctaatct tacccaatac ctaaacctaa cagctacctt actaactatt aataagcggc 1380
aaattaagac tttattgaga gaaatgtcgt agttaatagt taacaagtgt tacctattct 1440
aaagtgtaac cccaaatttt gtccattccg catctgtgca atatttcatg tctttttaag 1500
caatatgagc agggaaaaga caaaagttcc ggtaagagcc gttaatatga atgttgcagt 1560
gactggatta ccaaatcagg aaatgattca atcttttgaa ccagttcttt ttaatgaatc 1620
aatttattga gttgacaaat caaactcaat attttgtaca tgaatcaaaa ttatttgttc 1680
atgaactgaa attgcctcac tgattcaatt atctgctttc agcagttatc catttaacag 1740
ctcaccagag gggaagatta agattataag caaataatga attaaattaa tttaaaatat 1800
tgtacacagt actctacatt taacagattt ctaagattaa acactgcacc tttacataga 1860
aaatctgtct tgtttttgcc ccacagcctg ctgatctgag tcccctcttt ctttttacag 1920
aacactgaaa ctccacatgc aattttaata atttctgttc tgtttacttc tctgatagtt 1980
tataaaagac tgtgatcttg tttctgaata aaaagtcctg tagaaaggga ttctggaatg 2040
aataaatgag tgaaagagct gctgagagga caaagcactt gtgaggatga aagcactgga 2100
catccattta ggccgagtgc ataccttcag cagcccagtg gatactgagt gcatgggtaa 2160
ataaagagca tttggggcat agagaaatca acaagctcag aagagcaagt ggccactaaa 2220
cgagaggatg atgggaagca aatggatgat aaaaagagag gggacaaaaa ctgggagaaa 2280
caaggtttcc tgataatttt gcaaatcaca ttattaaacc aaacaactct tgtcaaaaaa 2340
tgcttaagtg aataatagtt cagccagttt actcaggcca tccaagatgc agatgagttt 2400
gttacttctc ctgaacagat ttgaagaaat gtagcattac tttatttgct caccaatgga 2460
tcatctgcag tgaatgggtg ccgtgagaat gagaatccaa acagctgata aaaacatcac 2520
aaaagtccat taacaatttg tgaatcaaaa agttgtgttt agaataaaca aatttattat 2580
taaaaactcc tctatccata ttatagcttt ttccagggat aatgctgtct catctgaatc 2640
aaaagagaaa tattcacaga taaaatacca tttgcaagtc taaaacagtt cttatacagt 2700
ggatcattgt aatgcatctt agctgtttgg actcattctg atgctcccat ttattgtcat 2760
gccaggtatt caatagtcaa caagtgatgc aatgcttaat ttctaccact atctatttac 2820
ctttacctat tatctacctt tatctatttt atttaccttt aagttcagaa tagtaaatca 2880
tgctgctagc aattcatgat caattctcat gaactaataa aatgtattct gcagtgcaag 2940
ttgtttaagt gctttaagtg caaaatgtct gccaaatgca taaatgtaac atgtaggcta 3000
cagcaaaaat gacctacacc cagaactgta aattagtttg tcccttcaac acacaaaaaa 3060
aggtataaaa ctaggattta aggaatcagt gaaagaatca atagaggaag gggctgccaa 3120
aggacacaaa tcaagacaga gaaaatgaga catgagggta atacacttcc acgtgaaact 3180
gtcctctagc acttcctgtc ttctacttca tctctttcta acatactcta aaattagatt 3240
attggaaagc acatatttta aggcctatta tgtaagtatg acaaagataa cagctggttc 3300
agggaacaaa tcaggtgttc agtatccaga aagcaggtgg ggaggctaaa tgctggactg 3360
cagaaggaac aggtatttat aatctgtata aggcatgcat caaagcaggt gcatgtgcca 3420
cgggtgtgag ggcaggtcag attgctaatg cacaatttga gtgatgtgaa tgaagcagcc 3480
aggtgcccga ttcatatgta gtgaagtggg ctaatcgatg tgcactgaaa cacagggttt 3540
ccagggtgtg agatgtacaa cctgaaaagc gtctccacat gtggtttgtt aaacaggcag 3600
attaaatagc acattacacg gcactaagta ctgcataaac cattctaaaa tgaaaggcat 3660
gctttttttc tctaacggca taatgaaagg aagagtaaag tcactaaatt cttacaaagg 3720
tgatacaagt ccatcctagt tggaggacaa agatgactcc aacaacatac tgaggcagtc 3780
tttcaagcta ttcaatgcat tacaatcaca tttattcatt tagcagatgt tttatctaaa 3840
gtgacacaat tatctttttt tttttttcag tagcatgaca ctcaaagtca gtaaccttag 3900
tttacatatc ttgctcaagg acacaaggat ggcaactcat taattgtgcc atattgggtt 3960
taattttaca gtgtttcaat tacacatttt accgctatct atgttaatct atgttaaggt 4020
caaattcttg ctatttacaa accattaact atgacttttg cctcaataaa ctcccaattt 4080
gctgcttatt aatagtcaat taggtaattg ttaaatttaa gcattaagta ggaattggga 4140
actaaaatat ggacatgcag aatgtgtgct ttttgctata atatgctaat aagcaactcg 4200
tatatagtga gatttagtgg gtccttatta gtgttgggtg taattgaatt acttttcctt 4260
tgaaaatgta aagaaagaga ttactcttta ttttttctgt aatttaatta cagttacttc 4320
ttatgcagtt gaacttgata ctgtgtatag actgtagaac atttatatac aatacaatag 4380
tggatttaac ataaaaaaat gtaaagccta accttaaagt gcatgctttt tatgcaccat 4440
tctcactata aatactttga tgagtcaacc tcttaactgt cacccccgac ccccttttaa 4500
caaagaagga atgtacacta ttcagactta aattattata attcataaac acttttaaat 4560
acagaccaaa gtttggtctc tttttaaaga agataatctg cagattattg cagaagtgaa 4620
atcattttaa aaaaatgcaa gcataaaaaa gttatagaag tttaaatgta ctgtaaagaa 4680
aatgtactat actattttta ttttttaata tatatttttt atataaaaaa tttattttaa 4740
tccaaaattg ctataaaatt aaagccatat gtctacataa gttgggttcc aaatttgaag 4800
ttcataaaat aatgccattc aaactgaatt gatttttttt atgcattttt ctgtcacaaa 4860
tgtatcaatt tctctttcaa tattatgcct atgacaaaat aaccaccaaa tcttgagact 4920
cagacctttc caactatatg tattttttca agattgtgaa aagtttgatt ctaaaagacc 4980
ataatatatt tggaatgtga cacctcccac taaggaggag gagcccacta aaagatttta 5040
aagtacgatt ttcaagataa cgcatgaatt tggaggtttt aagctttcag atgatatata 5100
atttacgatg gttgctaaaa cgtgataggg taaaaggaag caaaaaagat tttttgtgac 5160
aaaggtcaga actcctgtta tgatgaggtg cactcgtcat aaattaatct attactgttc 5220
ctacatattt ttgttacaac aaaaagtggt caaatatcta tttaggagtc ttagaccttt 5280
ccaacgatat gtagtttttc atgattagat tgtaaataga aaaacacaca tataaatgtc 5340
ttattctgca agactttatt ctaaatcctt aatcctaatt cctttccaat ccttaaattt 5400
aacaactact ttaccaagta ttaataagca gtaattagga gtatactaaa ttcatagtta 5460
atagtgagaa ttggactata atctaaagtc tgcctagaat aatttatgca gttatctaat 5520
atttatttta aagatttaaa agaacagttc catttctatc tttgtatcat taacttgtca 5580
ggttaatata ggatttagaa agtaattagt aataagtaaa tacgtataac tatcttcgga 5640
gagagtaatt tgtacagtaa tctaattgca ctgttaaaaa tgtaattagt aagcattaat 5700
gaattacttt tttagagtaa cactggtcct tatactaaag tgttaccaaa cagttttgag 5760
ttaaacccct tgcggtgcaa aaaacaatgt gaaatgcaat aagccaatgc tgtaaggtca 5820
gtctgatctc ataagaagtt ctagtaatat gtaacatgta cacatgcatt tttgtattgg 5880
atatttgctg aaacagtagg agacaattgt ctaagagttc cacagaatgt tgatggggtt 5940
caaagttaaa accattgaat taaaagctca gatctttacc actaaaccat gatacgcata 6000
tgcatgacct tggggaaaaa tctgttttga gttgagggaa aaataagatt cttttgtcca 6060
tgttgcccaa ccttccttgc tcaaggctat cgactatgtg gcacattttg tattaaaaac 6120
cctcaacatc tcaaacatga tgagatcaga actgctatct gccacaatct cactcactat 6180
cactacaaga ttgctgatgt acacaacatt tccttacgac tgtgaaaacc catctcatgg 6240
ggctcagcaa gcatcagaat gccaattttc agttataact ggagaaaaag acaggaaagc 6300
cattaaaact agggaaggaa atgactttct caaagtcaca aaaagatacg gtagcgagtg 6360
gaaattaagg tcagtgttga ttaagcctga tatttcggac attattataa atgccatcat 6420
tgtcataatt ctgtactttt cataagggac acaccagatg gtttgtcatt tggacatcca 6480
ccattatctt acatgccagt gtttgggggc acatgatgga ttttgaaagc caaagtggct 6540
tggcatgatg ggaataacaa tgtgatccaa gctctggttt tgtttgtaca atagaccatg 6600
attgcccatg gttacataca cacacatgct gcttctctcc cctgtaaaag cacagaaata 6660
taagtatatt cataccaaca gatagggaaa gagaccaaat aggaaaggaa aataaggata 6720
tgcaaaacca cattggctag taggaggaat ttctcaaaaa tttatttata tatcgtatta 6780
atattgagaa aatgtgatga caattctgat attcaagaca ataagaaaag gaaacatatc 6840
tgcatgaaaa cacagatcaa caaacattac tagggtctat gatataacat gcacttttat 6900
ttgtattaat ctgcagatat gtactattaa agtaatatat atccattctc aaacgcattt 6960
cattgaaacc agaccatttt taatatgaca tcatatgatc caaaaagatt gaaatgataa 7020
ccctattact actgaataaa gctcaggtaa ggactatgtt ccacaaaaaa aaaatacatc 7080
acatgaagtc attatgagtg ttttctaggc aatgatggag ctcctgtaat cacagttcat 7140
tgtagctata tctggtattg tgatcttttt taataaatta atttagcatt tgcacttaaa 7200
actgaccaca gtgctgtgaa atagaaatgg aaattatttc aaaagctttg ctgatgttgt 7260
gcatgctaag gcccacattt tccaccactt taagagtggt agctgaacag agactcatta 7320
gaaatgatag gagaagggaa aaatgtaatg gagcactctc aaatgccatc ttaaaaaatt 7380
taaggacttt tagaaatctg tggcggtaga ctagctgagg gctataacgg agctgtctac 7440
tctagagagt gtaaaactga ggtgaaaaag caatgagtat tcgactcact agaaaaaatg 7500
aaacagaact aagattcaca ttaagccgtt ataacatggt ctctctaggg atgtacgtga 7560
aactgtgtga aaaacaaaaa atcagggtgg ggggttgcaa agttaaaaac acaataagct 7620
ttctgtatca ggatgaaggc atcacagtgc tttaactaat tgaaataatt ggctaattca 7680
aacccaggat atgaacaacg ctagttcagt agcacattga tactactata ataacaaaat 7740
aaactttttt ctttctttct tttttaccta ctttttgctg ggatcatcat gaagatagag 7800
aggcagctgg tcttgagcag tgaatcgtct aatgtacttt ttgatcaaaa tggtatatgg 7860
gatattaatg taaacaatca ggacaaaaag tcggatttgt caaaatatct gatatctggc 7920
atgaggcttt gcattgcaaa tgccactgaa tcatgtctta atatttatca aatagtgatc 7980
aatactggct tcaatctggc ttttcattta tttgtccttt actactgatt gtttacttga 8040
atattttctt gagcaatttg aaccaatata aaatatttga aagaaatatt tgaagactgt 8100
atgcctatac tgtattttaa tttagcttgt taattagtat atatatatat atatatatat 8160
atatatatat atatatatat atatatatat atatatatat atatatatat acacagtaca 8220
gaccaaaagt ttggacacac cttctcattc aaagagtttt ctttatttta atgactatga 8280
aaattgcaga gtcacactgc aggcatcgag ggctatttga ccaagaaaga gagtgatggg 8340
atgctacgcc agatgacctg gcctccacag tcaccggacc tgaacccaat cgagatggtt 8400
taggggtgat ctggaccgca gacagaaggc aaaagggcca acaagtgcta agcatctctc 8460
ggggaactcc ttcaagactg ttggaagacc atttcaggtg actagctctt gaagctcatc 8520
aagagaaagc caagagtgtg caaagcagta atcaaagcaa aaggtgacta ctttgaagaa 8580
cctagaatat gacatattta cagttgtttc acactttttt gttatgtata taattccata 8640
tataattcca catgtgttaa ttcatagttg tgatgccttc agtgtgaatc tacaattttc 8700
atagtcatta aaataaagaa aactctttga atgagaaggt gtgtccaaac ttttggtctg 8760
tactgtgtat atatatatat atatctatat atatatctat atatctatat atatatatat 8820
atatatatat atatatatat atatatatat atatatatat atatatatat atatatatat 8880
atatataagc atagagtact caatagcata ttaccaagtc ctctagtctc agattaaaat 8940
gacgaagaag ccaagcaaca atttaaatgt gattaaataa taattccttg ttctttgctt 9000
taaaaccaca ttacaatttc tatctaacta atataatgta taaagcacac aaatggatga 9060
gcattcttca gaaagcttgc atctctctct ctctctctct ctctctctct ctctcaaaga 9120
ctccatcacc gatcttcctt ttctgtaaac ctgtatgccc aggtgtgcca cttaaactcc 9180
ctcccttaat tacagaagcc tgacagcatc aatcacgctc ccaatgtgac gctacagcag 9240
cagttataat agcaccaatc taggtcctcc ccgtctgcaa taatcggcgc ctaatcattc 9300
gacaagtctt gccctaaagc acacacaaaa tcacatgaga cttgagtttg acgcctttag 9360
aagcagcagc accttaatag aacagtgact gaaacatcaa aatcgggata aacttttaaa 9420
agcccttttc tttgttccta aatgaatgtt aaagaggaaa tccattggca tgtagtccga 9480
tccctaacaa gcattccttc gtggcttaaa ctctcacagc gcttcaaaca aatgggagag 9540
tgatataatt tgatatggag aggaagtctt attgcagctt agtaatagca tgaaactttg 9600
atcataaaag gtctgaaagg ccaacaatca tgattacgtc taaaagctat tgcataaagg 9660
ttaaaaaagt ggttatagtg tgagttactc tgaaaaataa taatttaagt ggctcagttc 9720
ttaacaatta cagaccaatt gtaaaataat aatttttaag cacagcatta gaaatgggcc 9780
ttaaaacagt tgaacaactt tgataatctc tgtactgtat cttagtgaaa ttgaatcttt 9840
caataaaatg aaagcagtca tatagctaca gtcagaataa gtggcctaat gcattctttt 9900
agtatgcagc atgaagaaca gctcttgaga aatgatcata aatggtatct tttgacatat 9960
gattatatgc aatgcactac ttagctcaca ttgtccataa accatgcttt cattttgtat 10020
tcgtgcttac aataaaataa aaacttacta tccactttca tggattgaaa actagataga 10080
actgtcatac ttctgtttta actttttttg tgcttttctt gcatatttcc tgctttttgt 10140
catgtcttca cttttgttta ccacttgttc tttgaattga tggattaagc aagacagaaa 10200
cccctcctaa agcaaattca cactttcaga caaaaatata tataaaaaca catttataaa 10260
tacatacatg gttgcgatct tccttgttta acttttgtga acagtagatt tcttcattca 10320
ttttgattag agtagaagtc atgtccatag tttggatgtg tctgctctct ctcggttata 10380
accccccttc tttccatgtc tcaaccagcc ctgcactaga gcttgaaatt gattcagtgc 10440
caaatgcaga ttacacacct gcaatatcaa agcacaggtt tggtattgtc tgtgctacag 10500
ggctatcgag acacagctgt aaatgggaat gctaattaca tcacatgacg tgggagatcc 10560
gtctgttgaa aacaagagaa cgaggagatc ctttccacgc aaatcagcca gtattgtctt 10620
tgttgttttt acaatagtta catcgactgt ttatctgccc tgaagcaagt caatggtatt 10680
cacggagtct ttgctggaag tgttttgcaa tacacttttt caaattaatt aattcagcaa 10740
ttaatgaaaa tgctgatgca tttgtatgca catgcataca tctatattta tatgtgcctt 10800
gatctaaacc acacacacat tcagatgcag atataaaatg ctcacattac tggcactcag 10860
tttttaacca aaagtactat ttcagtattg tgtttaattg aacactgcat actgaaactg 10920
acagggtcgg ggagtaactc gtagcatgta acagtgtaac agtacatcat ttaattaaat 10980
actttaactg taatctgtaa ttacataaca gttacttagg aaaatgttaa caattacaag 11040
aaagggttac atctaaatac tttctgtaaa acagatattg gttactcaag gtaaatttta 11100
aatagggtaa cttgtatatt tctaagtaac cttcccaaca ctgataatag gtcctaactc 11160
ctaagagaag aatagaatta agggagaatt aatagaatta agggagaaat tacaatccta 11220
gctgtaattt agcctaccct atatatatat atcctataat cctagcctat atatatatat 11280
atatatatat atatatatat atatatatat attttttttt tttttttttt tttttttttt 11340
ttacaaaact ggttactagt gctccaataa ttttggccac cttagactga tttttacacc 11400
agagcagcaa tgtctagcta ttcttacttt tcagagagta aagtaaatca tcatgtcttt 11460
aactaatcac actaatatat ccctcatatt atcaaaagta caaaatatac aatatgcaat 11520
caaactgtta tagttaattt gtctacttag gttcttcttt atacagctgc tcaggacaca 11580
cttatagtat gtgtaaagat gtcaagagtc aaaaatatag cctgccaata atgtgaggta 11640
actgcgtata ctatggattt acaagctctg catcattaaa gttttacagc cggtcaggct 11700
acgtctccat atgtcacttc attaattctg cagttcactc agagggcttg gccagagacg 11760
aaaaatgcca gcagaagatg gatgttggat agagaaaaaa aacaagtgtt caatataggc 11820
aacttgccct ggtgtggtaa aaaatgctcc atttaagagc aggtcccctt ggtcattcag 11880
actaacatcc ttatgccaaa aatggtcagc gatggttttc taagaaaagg tatatatgga 11940
ggtcagaggg gcaaggctgc aaagccaagc gagtcatcac aagccaatat cgccactatt 12000
gggaaaggct agggtgagta gaaaatggca ggagattgac aggaaaagag cgcgatgcac 12060
ggtttaataa aatctggact catctgaaca ccaatggaag acttcctgtc acttacattt 12120
ggacagatta ctccaagact tttggagcaa gcagaaagtt tagattaaat gcattgctag 12180
agaacaacag agaatgtcca tattctacat ccctaatcct acctaatacc aaaagttaac 12240
aattacctta ataacctatt aataagcaac aaattagtag ttttttgagg caagagtcat 12300
agttaatgac gtggtaacag cgcaaactgg gttaggggta gggttagaaa taaagtgtta 12360
ccaaagaact tacctatttg acctcactaa actactatta atttggatgg aagactagat 12420
gagtatcctg acctgtcatt gatcaaaata tactaacata aatggattct gatgaaacta 12480
ctaagtaaga aatactggtt acatattgga ctagcactag tataaagaac atattaattc 12540
tatattctgc atgaccgtat tgtagatcct ttaactccta gtcataccta aacttaacaa 12600
ctaccttggc taagatatta ggagtttatt gtggcaaaaa tcatacttaa tagtttattt 12660
atactgataa ttggtccatc actagtttct aactaaagtg ccagagacag tctcagttcc 12720
cactgcatcc ccatagcaac caaccaatca gccaattaca ggctgagctg aggacccatt 12780
catcacaaag tcccaaccat cacatgccat acaaatgagg ccccaaaata caaaaagcaa 12840
atatgcagaa gttcaggatt acatcgcaat ttatctactt ctgagactct acctgaagag 12900
gtatagaagc agttcagatg acatgcagag gttgataagg atgacttgaa ttctctgtga 12960
gtatcaagca ggagggaggt taatgatgaa tgagcaatta ctcaaacatc tgctgccacc 13020
ctgtttgttt tcctagcact gccaaaaaaa taagttccca tgggcgattg cctcctccct 13080
cacccacccc actgccatca gcccattccc atttggctca gccttgagtc gcccagctgc 13140
tctacctgcc tctggacagt cctatgggcc ccagaatgag gaaggaggga atccaagaat 13200
acgtctcatg agtgcacaca gcgagcagct ctttggctta gcagaggtac ttcattactg 13260
aaacagaatc ggaagcaagt ggcagccgtt caacttaaag tgaagtagtg atgcagaatc 13320
tggggttctt gctatcgtta ggacggattg gattcactct taagattagc ttgaattgat 13380
ctgccttatc tccctgtctg atgtgctgtt tagactgagc tcccgttctt ttccctgtgt 13440
tgagccgagg gccttgggct cggtctaatg ccattgattt ctcctgtttc aggggttaaa 13500
agtgccatgg ccacttagac ttagacagac aagcaaagga gatacataat ggtaagtgat 13560
tgcttgttaa tgaagatgga ttgcaaggtc atggaaaaat tatcaaaaaa ctaattattt 13620
attatttata aataaaagtg tatgtattat atacagtatt atactgtatt ctataaatat 13680
aatagtcatt ttttatcatt ttcatattat tgttatcatt tttattattc tttttttgtt 13740
ataatttata ataaagttgc atttattagt tcatacatta catataattt aggtatcaca 13800
aactaaaaat acaattattt tatatcatat attaattcat gttaattcaa gcttgttcat 13860
aatacagtga cttatgttat ttcataaaac ttgcaattta aaaaaaaaaa ttctgtaaaa 13920
ttattgataa atgaaggctc atgataccta attgatacca atttaacctt actgaaccaa 13980
gtgtttcata taattctgtt aattagttgg cataatctga ataaaaacac aatatgccaa 14040
ttaattaaca gaattaatgc aattaatagc ataaaatccc cccaaatatt tttaaaacat 14100
attacatgta aagtacataa attacattaa tgacagatga aagcattaca ttaatgacag 14160
atgaaagcat taaataaata ataagttata tatatatggg ggggctgggc aaatttctac 14220
acaagtagta tttaaatcca aagacaaata cctaaggtaa aagtgaaagt gtgaagtgcc 14280
ttcatgtctg gctttgtgct aggcatgtct gaacttcctt ttcagattct atatactggg 14340
attgaaagac cccactgtct cccaccagga tcatttcaca gtccaatcag atgtgcattc 14400
agcttcctct ttttcaccat tgaccaccaa caccccaccg actgggagaa agccagatat 14460
ctgcatgcat ctgtatttgc atggaaagca cttccatcga gcaggtggta acaagcaggg 14520
agaaccgaat caaaagagac ggtgaatatc tccgcaagcc tctcaccaag aggtaatcag 14580
caagcagctc cttttccaca ttcagatgta tttgttgata cgctagagag tgcttgaaat 14640
caagctgtct taagagtctc tctaaaacta ggtctgtcac ttcttaaaaa gagagacaca 14700
cttagggata tttttggaac atgatgaaca tgatcagttt acactgattt tacatggagc 14760
atgcaagaca aatgacttca acaaaacatc ttacataaat acagaggaac acaggccatt 14820
ataagacata acgtttacat ctattaaaca agctcgagtt gagtgaaatt ttgattgtaa 14880
ctgctggtta tgctgttctc tttttgattg caatattgct ccagctttaa atgtattgta 14940
taatgtgaag agaagagaga acatgaccag aagcaacaga ctgcaggagc tgctggtaaa 15000
aagtgtgccc tgaaacagaa cccatttaag ctaccactgg ccaacagatc tggctggaat 15060
gatcacagtt ttccctgagg agtgagagta catgaaaatc tataaacatc tggacataaa 15120
gctaggagat tgactcttgc accagggtat tcttgggtaa tttcgctgtt caagttacta 15180
gcttttttta cgaagaggaa aaagtattag tgcaagaata aatttgtgcc caacacaaat 15240
acctgaagaa ctccatgaag gaaaatccat aaccatgctg ttcagcaatc ccagcacaca 15300
ctacatttgc agatgctcca atcagtgttc catttccttt gggaatagaa agagaagaac 15360
aaaaaatgaa cgaattggaa aatgaatctt ggataactct gatagcttga ataaacatag 15420
acattcactt atttttacag aaaaatacat gtttgcctaa gtgaattctt ccatatacac 15480
tctaaccaat cacatgagtc tgccttgaaa gataggatct gagaatttgt aaatgtttaa 15540
atagcactat acaggtgcat ctcaataaat tagaatgtcg tggaaaggtt catttattca 15600
ttaattcaac tcaaattgtg aaacttgtgt attaaataaa ttcagtgcac acagactgaa 15660
gtagttcaag tctttggttc gtttagttgc gatgatttag gctcacattt aacataaacc 15720
cacaaatctc aacaaattag aatacttcat aagaccaata aaacaaattt ctttagtgaa 15780
ttgttggctt tctggaaagt atgttgtgaa tctttttctt ccacactttt tcctcccact 15840
caaccgtctg ttaacatgct tggatacagc actctgtgaa cagccaactt atttggcaat 15900
aaatgtttgt ggcttaccct ccttgtgaag ggtgtcaatt attgtcttct ggacaactgt 15960
cagatcagct gtcaacatgt caccatattc taatttgctg agatagtgaa ttggtggggt 16020
tttgttaaat gtgagccaaa atgatcacaa ttaaaagaac caaagactca gtgtgcattc 16080
tgtgcattca gtctgtgtgc actgaattta atacatgagt ttcacaattt gagttgaatt 16140
actgaaataa atgaaccttt ccacgatatt ctaatttatt gagatgcatc tatacgtcct 16200
ttacaaatac aacactgtac caacacagat ctttataaat gaatattaga attgattaga 16260
attgtgcaca gcagattttg ttatactgat tgcaatttaa agttctccac tgtgcaatca 16320
cttatgttag agtaacagca atgaaatgac cttcagtgct aagttgcaga ggtgatttag 16380
caagtttttt tttttttttt ttgtcaggca tgatagcttt ctgatggagg acagaggtca 16440
tcacttaatc aatagcatgt ctagaaagat ttactctgaa gcatctaaac gtgttcttca 16500
atgtattgtt ccatctctaa aacttccaaa tctgggatga aaccagtgtg atgggtcttt 16560
agcatgtcat aaatttctgt tttagactgt ttaccatacc atgtcataaa caatgatatt 16620
ccaaataaat atgttaaaac acacacacac acacacacac acacacacac acacacacat 16680
atatatatat atcaatatat gaaggctctt cacaaatgta ttttctgatt ttgaacaatt 16740
taaaactcta aaggcagttt acactcataa atttgtcatt ttcttaaaga catatttctt 16800
aaagcatatt gcttagcctt gtagaagaat ggtcttcata tgaaaggtac acatcttgaa 16860
aggtgtcagc gtgacaaaac tgtctgcctt atcatttcat ggatcgatag tacaggtaac 16920
gcatttcctt tgattaggct gtaggactgc cacatttttc tctgtgtcct tagagccaaa 16980
caggcaatga ggcattttca gatggacttg taagcataca ttcctaaatg tagagtgatc 17040
tattgtgcac tgtggtgctt tcaaagccag tgaggaagaa gtctgtggca ttgaaaaacc 17100
atagcttatt aaggctgaca aaacgtaatg aaaagagacc ttttttgaat tactagtatg 17160
gatgctagtt atatatcaca gatatatttc ggcaaagtaa ttacttctcg catctatttt 17220
tcagagaaaa agcaacaaat tgtcttttca gctcaaacct ggtctaaagt ctggcgcaat 17280
gttttttctt tgttgcttat taaacacagg cacacacagc agcacacaag catgccaaat 17340
attaaaaatt aaaggattgc aatgcataag attctttttt gtaggctaaa tttatatata 17400
tatagatata tatatatatg cctacatgtc ataatggata gtcatcgcat gtatcagaat 17460
taggctattt gctcgcacgc gaaacagctc cgtctcatct tggagacgcg ttctgtcttt 17520
gcgcttgcca aatggcacaa aaaacaccca ttactcatta agaaaatagg gacaacccat 17580
ttagaccatg cgcccgggtg cgccaaccgt ttttccgtcg ttaaaatagc taaagaggat 17640
ttgaacatgc cctgagtgga cctgcgccat gcacttcaca ctttgtgttt agatcgttaa 17700
aatagggccc atagtgttca ttacaggtca tcaaacgact tgaaccatgg ttgctgtaat 17760
gatatgatac ataagagagt taataatgca actgacctcc aaggcaagca cccatagcca 17820
atgcaaaaat gagaggttta attggtaggt tgacatctgc atcttgactg aggtttataa 17880
gcacaggaat ctgtgaaaga aataaaaaca catcagataa atattttggt aacacttaac 17940
gtaaagcctt gcttatatta gcattataaa actttattaa aggctataat tcttatagac 18000
caagatggca ggaccttcaa gacctagatg gcggtgcgta cgcatcacaa ggctcatcgt 18060
ctctccagtt ttggcaattt tgctatattt ttcctgctca tctcgggtct gttcatactg 18120
aacagctttg ccttaaccct ctggagtcgg gacaatcctg aaatctaaaa tgttgtcccg 18180
aattccaaat ctggccctaa ttgtcccaaa aattatacta aagcaaaatc ttgagtaatt 18240
attgtctgat aaacattaaa aactgtctgc ggaggttgag tcgtcctgca accagcccct 18300
gccggctgct cattggctgc agcatctttt tctaagttct aaaaaaatac cgtaggcggc 18360
tggcacgaat ttagatattc atttatctaa ttaatctata tgcacaaaga caatacggcc 18420
tttttgtccc ctttttgttt taaagctgaa tgaaaagagc gcaagttgct gcagctgcga 18480
ggaggacagt gatgcacgcg tacaggagtg attgacagtt cgcagcactg tgtacaaaaa 18540
atactccgct acacaattat ttatgttatt tttgtttaag cttattagcg ttagcgttac 18600
agaaaggtct gatttacgca ctgttacaac agtcattgtt tttttttgtt ttctttacag 18660
tgacatttga gttcaagatt ttaatgttgt tatttcttgt ggcagactta agagtaattc 18720
cgccccgaat ttaagccaat ctcatctcgt catcctattc taagggtatt tttaaaaatc 18780
ttttttgcac attttattta tgttcaatag ctctttctag ctcaaggaaa tccacaaact 18840
aataaaagga tttatcattt tttctaaggt cgtttgctgt atataaaacc attaaatata 18900
gttgttgtta cctcagggga tgagaggagt catcaaaaaa aaaaaaaact atatatatat 18960
atatatatat atatatatat atatatatat atatatatat atatatatac tgaatcattt 19020
taaacggttc gcgtctccag tacgtattaa tccacaaatg actttagcag ttaacttttt 19080
taatgtgact aacactccct ctgagttcaa acaaaccgat atcccacagt aatccatgta 19140
ctcaaacagt acactgactg aactgatgtg aagagagaac tgaagatgta cacagagccg 19200
agccagataa tgacagctcg tttctgtcag tttctgtcag atgtgtccga ttcgagaacc 19260
gaggagctga tgatactgcc tatgtgtgat tcagggtgaa gcagaccgac acacagaaca 19320
tctgaaccga actgattctt ttggtgattt actctgaact gattctgtgc taatgttatc 19380
agcccaggta aactgaaggc tcgaatcaag ggcaatcatc gccaatgacg ccattacgtc 19440
gagcgcaaaa gaaccggtaa accgttttct tcaaccggtt tattgaatcg aactgtcctg 19500
aaagaactac tgttgatccg aaaatcgatg caaccggttc ttgacttgtg aaagagtcaa 19560
tctttcgttc attatctggc tcggctcggt gttcatcttc agttctctct tcacagcagt 19620
tcagtcagtg tactgtttga gtaaatgaat tactccggga tattggtttg tttgaactca 19680
gagggagtgt caggcacatt aaaaagttaa cagctaagtc atttgttgat taatgcgtat 19740
tggagatgta aaccgtttaa aacgattcag ttcgatttgg tgaactggtt caaaaagatc 19800
caattacatc gaatgattcg ttcgcgaacc agatatcaca aactgcttcg ttttgaactc 19860
tctcacaaca gacacggaag agaacacaat gctgaataaa gcttgctagt tttggaccag 19920
aatgtatttt caatgctcaa aatattctaa ctgaccctct gatgtctcat ggactacttt 19980
gaagatgttt ttcttaccat tctggacatg gacagtatac cgtacacaca gtttcaatgg 20040
agggactgag atctctcgga ctaaatctaa aatatcttaa actgtgttcc aaaaataaac 20100
ggaggtctta ctggtttgga atgacaggaa ggtgagttat taattacaca attttggttt 20160
ttgggtgaac tatcccttta aggactcctt tcaccctgac caaagactgc ttaacctcct 20220
gccctccaag aggtgcttca agagcctccg gacaaggacc agcagactcg gcaacagctt 20280
tttccccaca gctgtctcct tactgacttc taccaataca actaaaccac tgaattatac 20340
ataaaggctt atttaagtat taccagtata ttatatatag tgtgtatgtg atagatagag 20400
acagacagac agacagacag acagacagac agacagacag acagacagac agacagatag 20460
atagatagat agatagatag atagatagat agatagatag atagatagat agatagatag 20520
atgccctaat cataattctc atagccaatg ttttcaaaga aaagcaatca agcaatgcct 20580
attacaaaca accatctgtc aagaactaaa cattgtgtat gtcagggtca cgaagaatgt 20640
tatattcaat aattctgaca gccgtccaac ctattagcag attgagtcat attcttctgc 20700
tccacaagtc aagaacaaga aaatcaatag ttgatgacat tagatttctt tatccatatt 20760
tctctctttt tgcacagaca cagagcttga ataaacagaa aatgaaaata tcatgaaaca 20820
gcatgtatga tccaagcatc accactttgg cccaggcatg aaatctacat ggatataaat 20880
gagacaaaaa cactccacaa tggctatagc catcagtact aagcatgagc atataatggt 20940
gaaaagcaga gaatgcatcc ctgtggcgac aacaacagat atgcatgcat ccgtttctca 21000
aggcaaataa gcatttgatc ttcccaccag tgtagtgtaa tttaaagatt gcatatttgc 21060
agaaaatgtc ttctgccttg aagatttctg tgtgtagcca cttgtccgct acacgctggc 21120
ctcccagcta acatcagctt cagctgcaat cgacttgaat aaattacaca gcacaactgt 21180
gattaaattt tctactacat ttgccatccg gttcattcag ctgtggcatc gccagcatgg 21240
atgggagggt accagaagtc aaagcaaccg tacacttgtg ctgacaagaa aatagcagtt 21300
ttatgtttgc agtggagcgc aaatagcaca tttttaatct gtgtggaaga tcctaacttg 21360
acacaggtga catggaaaca tctttacagc tatcacacat ggtctctgta atcataactc 21420
tgcaatctta aatattagta tatttatcac aaataaaatt actttataat taatgcggat 21480
taacaaatca gcaaattatt attatttttt tttgaagggt cacgtgatac tgaatactgg 21540
ggtgatggct gctgaaaatt cagctttgcc atcacaagaa taaattacat tctaaaatat 21600
tttaacagaa aaaaaaaaat ggaaaacaga tatttaaatt aaaatgtcat tgtgagttcc 21660
agatcctggt tctcaccagg tggttcgttt gggatattct tgtagatctc tttcaggata 21720
accacttagt gttcctgaaa atataatatc aattgctgct taaaggttta ccacaaagac 21780
agaaccttag ataatacagg ttaagaatgg tcaataatgt tcaaattaaa tgatcgcctt 21840
cattaaatcc cacaagcact ctgatcaagt ttacttattg caattacaga acaatccttg 21900
gcaagtcatc catcaaatgg ccagggacac aaaagagata caaacatggt gaggacgagc 21960
agagacatgt ctacagccat gtatatgtca tattccattg ccgttgagac cagggacaga 22020
agtaaaccgc ttcagtattg atcttcaggt cagatgttta atgctccatg tggatgtcag 22080
tgattgtgtc atgtttgaaa aggtactcaa cttgaacacg ctgaggctga tatgtgaacc 22140
taaacatggt gagcacaatt tagaaattgc tttatgcatg gtgtgatatg aagtcaatac 22200
ttaaagcaaa tgtctaacca cagaaacttg ttgctcgaac cattatgaat ttccatggcg 22260
gactattttg gttagttaaa tggtctttct aatgaagctt gttgaccaaa tgaggcttga 22320
gggttaagtt agttttgtgg tccgttgagg acaccaccat accagcattc agacatactt 22380
ttcaagagca tggataaaaa tagctgaaca catgctgatt tttgttgata gtagagtcaa 22440
aaacaagaac attctgtgct ctacagaaat gaagtgtgtg tttaactgca tggtcttttt 22500
agtccagctt caaattatta gagggcactg ctgagaagtc ttttctgtat ttatacagaa 22560
gtgatccatt accaccacag gtgtatgctg agctcaagca catttcactc tgtttatctc 22620
ttatttttga cagagcgagt gaaagagaca gacatcgagc aagaataaca ctgaatagga 22680
cagagttgca gatcccagtg gctaactagt catccaacaa tcgactttat gtacacgcgt 22740
cctaagaaat atactctaat atatataata ggggtcagtt tgacaagcta attatactag 22800
actagtattc agctagttgt tcacacaaca actctgctta actagttctc aacctaacaa 22860
ctaatgtagt tctgttcata cctactacac acaagtcgag aaagtaagtg aaagttagta 22920
aggaaagagg tcaacataga cagatcaaat gaaacgtgtg gaaaacgctg gagaaggagg 22980
aaatgaaaag gcttttgaaa tgctaagtga cttgtctctt catctgccct gcattcttcc 23040
cttctgctca tttggcagtg tgcgatcggt gcacagctct gtctgtttgg tgccatgttc 23100
atcatatcag ctcacagcac gtgttccttc atgattcaca tgattcatgc gccgctctga 23160
tagcacatca tcactcacta ctgttgctca cacatttcaa ttgactatag aggataagat 23220
gcactatttt cacctatttg tcaacagaat gtgggcacta ggtaacatgg taagcagtga 23280
cggcagtgtt ctgcagtgtg acatgccata ctaaaagtat tttaaaaagc gattaattta 23340
taatcataaa acggctccag tgttctcctt tggataaata atgtttaaag agtactggga 23400
catttcacgt tttactttgt tcccagggat taaattgaaa gaattaaaaa aaaattggca 23460
gtggttcagg gtctctaggc aagatctggc aatcctttaa cttaggtaag ggagttcagt 23520
cattgtcatt acattaatag cttcaggctc atccgagatc cgcctggttc acatgaggcc 23580
agatctcctg tcttattttg tgataaagat caggtgactt aacttcttat ccacagaact 23640
attttataaa agacttcaac ggtctcagca tctcatacta tatacttgat aatactatgt 23700
ttactgtaca ctatatttat tattacaaaa ataatgcaat ttaaattaat aaattagctt 23760
aataaattct attttaatgt atattaaata gcaatatttc acaaaaaagg ccaagtacta 23820
ataaaaagtc tttgtaagaa atataaacta gagacaaact agagtgtgat tcagagctat 23880
tttttcctct tctttaccat atatttgtgt tttacgtgca aattctagga aggagtaagt 23940
gagttcatta ccatagtggc agtgaaggga atgttgtcta taagagagga ggccagtgct 24000
gagacccaca tgaccaaaat gatggcgatg gccaaccgct cgtcctctgg cactgcctgg 24060
aagagaagat aacgataaaa tgtcacaacc aaacacacac acacacacac acacacacac 24120
acaaaccctc tctctctgtc cgtctcataa aggtgcgtag atgccaacac aaaggtggga 24180
gggctttgca gacaatgtgt tcatggtaca gtcacattgg attcattatt tcacactctg 24240
ttgatttcat gaaccgaaac accacacatg tacacaaact gacgtaaaaa cacactctca 24300
ccacatgcct gttttcattc cagctatgat gtatgtgaaa acacaccgta gtctttttat 24360
tagcatgtag gaatgctgtt tattgggggg gggggtattt taatcatttc cccactattt 24420
ctctctctgg ttgttcatct acatggtcag attttcgggg gtgctggtgc tgctgattgg 24480
attgaatgca tcagacctgt catgaataat tgctgtgatt gtaaaaggct tgcacaccaa 24540
acccaagctg aagggtcttt tagattgtga tcaccagcca ggaagagctg gacacttcca 24600
ggtctatgaa aatctctgta tttatggtca ccatagacct actactggat caaagataat 24660
aataatttca gccagccaga aaatttaatg aggatcattt ggctggttta cctaaagtag 24720
tttatttttt atttttttaa gtgtggaatt tcatgctctt cgaattatgg tccatttgtt 24780
gaaaaacata cagaataaaa cagcatctat ccactttttc aggagccttg tttttttttt 24840
catatagatt tttttaagtc tttgttcaag agttataaac catgaaccaa atcaaccagc 24900
aatgaggtta atgacattct gaagcaaaaa tacccacagc cccatgaaga actgtgaaag 24960
acaaacaaaa ctacatattt tatgtttact tcaaaatatg catatataga caaatacagt 25020
actaaaaagg ttctttcttt gcatttatat tcccaagggt tctttatagt gaaaaaaaaa 25080
gaaaaaaagg ttattgatta taaaaaatat tcttcacaaa aaagggttgt tttaagaact 25140
gttcacaaaa tggctcttct attgcatcca aatccccttt ttgaactttt atttttaaca 25200
gtgtacttca tttgcaatgc ttcatgggat gtgtgcaggc aaatcaggaa atcgataaag 25260
aattcctttt tcgtaatttg cttgctattc tcttataggt ggagatgtca ttgctgaatc 25320
gttggataat ttagtttcgc atctgctgtt aaaatgatta tttaaaaaat attgcaggca 25380
gatggacatg tactgtcaat taacaacctt gtactgtagc tcacactgta agtacatgtt 25440
agttaaaaat caatccttaa atgaatggga tttttcagaa accaatcgtt ggcacttcat 25500
tttagactaa gctgcagcac agaactcggg caacagtcaa tctaactcta aatacaaact 25560
gcaactttat atctaaaaat ttgattttaa ctctcagaaa ttaaccttat atctcacaat 25620
gacctattat tttgcaaatg ctggtttgtt tcctataact gtaactttag attacaatct 25680
tacaatgtga cttacaatga ctatcttctt acaatgacta tcttcttatt tttataagag 25740
gaggcagaaa cagacctttt cctcaaaatc cgatcacaag tggtcacagg agacacatct 25800
gaaagatgtt acatcaaggt gtaaacagca tgtgtcgcct tcccacttgt gatcgtatcg 25860
cccaatattt aacaccactt tttgggatag attttctgct gattgcataa cacctttagt 25920
gagtcgagcg gcaaagcaac acagacagcc catgcaaata tacattccta gtgaaatccc 25980
cccaaagact gtatcaaaca cttctggagc aaatactcac ttttatcaac actgctgtct 26040
gctccccgat gtagtcgatg agctgcagat gtgctagggc cttaaaaaca caccacagag 26100
aaaatcaagt catagaccag aaaccaaaac aacagacatt taacctgaca gctctgattt 26160
tccatctttt aaacaatgga agtggaatat cagtattcat ctatttttgt ctcgccgctt 26220
gcggtgcaca ctggtataag tgattgtgaa agttggctct gttatagagg gcaaacagtt 26280
tatcttggag cagcgataag ctccccactg ggcccaaggg gtgggcttcc ctgtgtgaat 26340
actgtcctcc taacaaaaca aaggattaaa ccaacacaaa caacaaacct agcgtttctg 26400
ctgctgacat gctcactttc tccttactta gactccgaat ctctaagtca ccctctttct 26460
ccttctttat ttatgaatgc aatagataaa aataaacaga acaatgcact actatataca 26520
ctataaatat tttatctttc atgacaatgc acttatattt tatattaaaa ttattttgtt 26580
ctctataaca atgcactttt tccctcgggt ttgtaaataa caaaaagaca cattcaattt 26640
aggcagggaa aataacaaat atatataata tatatatata gacataataa aaatatatta 26700
agcctataca taataataca ctattacata tctttcatga aaacgcactt taaatactta 26760
gtttcgttct ttttcacact taaaaaaaaa agagtatata aatataaaaa cagacacaaa 26820
catgtatgtg tgtatgtgta agtgtttgtg tgtgtgtttg tgtgtgtgtg tgtgtttgtg 26880
tgtgaaatag atttaataaa aaataaaaag tagaacacat tttcatacaa taattgtgca 26940
aattaattta caagtctaat gtaatataat aatataatat ttttttaaga tcatatttta 27000
ggggaattac actttttatt acatttttat aattaacatt tttgtttgca tataaaaaaa 27060
aaaaaatgac gggggtacat ttgaggtatg acaggctcct aaaccagcat ccaaaaacac 27120
aacatggacc agtgaccaac taaactgatc ttggtaaaca atgactagcc atcactgtga 27180
tgtaacagat gacagaacat tgggatatgt gggcgtttgt tgagcattag catacctcca 27240
taagcacaaa cagagcagcg aagaacaaca gggtggccca ttccactctg tgaagaatga 27300
tttcaaagtc ctgaatgtca gccagcacca gtaaccacag agcccccaag atagcgatcc 27360
aacctgaggg acaaaacagt acatcactgg agatcactgg aaaacaaccg agaacacggt 27420
tcacacaaac atttgatttc ctgttgttgt acgaaaaggt tttaagataa tggaatcctg 27480
gaaaacagcc gaccggtggt taatgcaatg catcaatcat atgttatgtc tctatctatc 27540
ttgccttccc atgaccataa acactttctc atgagccgac cacagcggtc ctaaatctgg 27600
cattccactc acacaaaaaa aaacattcag caggagagag aacaaacagc ggcattcaat 27660
tagaaacaca gcccagccac cccacaaaca gactcataat cgctctgcac atcgatacac 27720
tgacaccaca ggtagtctgc atcaccacaa tggactacgg gctgtcaggg cataagaata 27780
ataagccagt tactggaaag ccttcattaa aggcttctgt gatgtgcccg acactgatct 27840
aagaacctca ttctaaataa atgatgggaa tcgcaactac aacagagata acagaacata 27900
aaagtgccag tttccctgag agaggagatc atagtaatta attctgtatg cttttgaatg 27960
tttgagaagt ctcttatgct cacaacggct gcatttattt gatcaaaaac aaagtaaaaa 28020
cagtagtatt gtgaaatatt attgatgctt ttaagatgtt ttcaaatata tatttggcaa 28080
cactttattt taggataaac tagttgctta ttagtatgca tattactaga attttagcca 28140
tttattagta ctaattaaga acatattaat gccttattct acatgactat attctacatc 28200
cctaatccta cccaatacct aaacataaca actaccttac taactagtaa taagcagcaa 28260
attaagaatt tatcgagaga aatagtgaag ttaatagtga ataattgttc cctattctaa 28320
agtgttacca tattttttga tgttgtttat tcttgtgatg gaaaagctga attttcagca 28380
gccattactc cagtcttcag tgtctcatga atcatgatcc ttcaaaaatc attctaatat 28440
gcagatttac tgctcaggaa acatttctag ttattaaaaa tattgaaaat aattgtgctt 28500
aatttcattt ttatcaatat tatttgatga atagaaaatt aaaaggaaca gcatttattc 28560
aagatataaa ttttaattaa agtctctcat gtcatttttg ttgttgttaa ataataaatt 28620
gagcatttta tgtgagcatt ccctgtgctc tgttcaataa atattagcaa aataaaagtc 28680
aatctgtacc acagtttatt ttaatcaact cagatgttat tgtgatatca aactgaaata 28740
tctctgaaaa atgttggtga aatataaaag gccattagct ggtgtgaaca ttgtgcatgc 28800
tgtcaagaaa tattgccaga cattttactg ctgattaagt gatgtactgt ttcccagaag 28860
cctctgggat taaaaacata tgcagcgtgt caggaacaaa atgttcgagt cactaaagtg 28920
agacggataa tacagcagga agcggaccag cgatatactg ctccatcaca tgcggtggta 28980
gaagtccatc ataatgagtg tgccatttag acatcaagac cgtgcacagc taatgtgcca 29040
catctcagcc tctgaccttt actataatag ccacagaaaa acaggcttta ttctggacct 29100
gcgtattaca tgcaactgac gttggcaatc tcaaaaaaac aaaaggacat aaatgactgc 29160
ctgcaaatgt tacaacaaat agaagccatt agcacactta atgtatgctt acaacatggg 29220
agaaacattt acaaggagta aaatcagact tagaaatgta gataagtgca ggtagtggat 29280
taagaatatg ttgtattccc aaaaattcta cttcgttaat aacttccaaa agttaggata 29340
gctccagact taaatcataa atagtaagaa tgatttacgg tagttaattt attgggttat 29400
ttaaaattaa ttgttgtttt taagcattgc aacaacaaca gatactgtaa gggaaacggg 29460
tcaatttagc tcaaagggaa ttattttaga ttttaaagag aatttgggca gaatcactgt 29520
ttcattgctg atcactgaat cggccagcaa ttcattgaac cattgagcca tataacatca 29580
actctggact gtatatcaaa atccaaatat agtgaaaaca ctaatgagta acaagatcgt 29640
cagtttaaaa cattaacttg taagcacaaa acactagata cttctctttt cagtataaat 29700
aaataaggct ttattggata aatcaaagac atataaacta atctagcaca tgaacacaca 29760
cacacacatt catacatcca cgcaagttgc agaaagagag aaagagagga aagaatgagt 29820
ttgagagaat gaaaaatgtg aaatcccaag tttacagtaa catgtgcaat tgcttagatc 29880
tgaacaacca tcaatcattt aattagccct tgcattgagt tactcaatga ggctaaaatg 29940
tatattaaat gcaccagatc agctagaata gggttgtgcc caagttttct aaagtgatgc 30000
gtttactgaa agcaaaagtt agcaaaaagg ctgtgtccaa catgaaaata ccaacaaaaa 30060
agttctaggt aaacaactgc tttggatcgc cagcttgtaa aaacatttgc caaaaccagc 30120
acttgagccc aaaaaagtgg ggtcttccat aaacattttg tcccagtgct ctgtgaattt 30180
aagccagaaa ggacaattgt gagtcctttc ttttttcatt atcaaactgc acaatcatga 30240
aaggctcaac tttctcacta tcaatttgac agcagaaatc gtcacaagag ttacaatcca 30300
acccactcaa agcaggatac caaattactg agcaattatc taaagacccc atttccacca 30360
gactatttcc tgttaaccat caggggcttt ggacttcagc cagcgatgcc agtgattgaa 30420
gagcctccat taaaataagc tggacaatgg tcaaacactt cctattcaag cttcccaaat 30480
ttagcacaat acacaacata tgcatggcac acatactttt gggactataa ccaacgctgg 30540
tcagtaaatg ctgcaacaaa cggatacact ataaatcata gccaaggagg caacagtatg 30600
cttccaattc tagcacaatt tgattaaaca ggtgagtgct agagattgcc cgtgggaaat 30660
catttaataa ggaatgagaa ggacaaaaac aagaatcttt atataataca gcgcacctcg 30720
acatttggac acctgtaacc agggcacccc gcctgcatgt agctcaggta agagtatggt 30780
gctgccgcac ttgtaacatt tatttttttg gcaacaagtg tgggatcagc tttgactagc 30840
caagcaattg taagtagtag cctacactat agtatttttg taaggtggtg gggatagaga 30900
tggagagtat tatttcgttc gtgtgttctt tgcgtaatgg ttgtggagaa ctgttaaata 30960
acgtttaaat agtcggagat tatttccttg tggtttgtgt aaaaaggttg gagatggaga 31020
cagaaagctt tatactgtac gtgtgttttt tgcgtaatgg atgtggagaa ctgttcaata 31080
aacaaattgc ttaaatagtc agagattatt tccttgtggt gtgcgtaaaa agattttgga 31140
gttaatagag ttgcgtgtga cataaacgtg cagtgactca agccagctga ccaaatcgat 31200
tgcattgttt tagcgttatt gtgaagtttg attaatatta tattttgttg taatattatt 31260
tcttgtatct aaataagtta catgtatgta taggctatct gaaattgtaa tgaaagtaat 31320
tatttcgttt tctttcgatt attaaactat tatttctgct tccgcttcag attaatagcg 31380
cattgcacat atctgagaac tgatgtctgt gtgtttcaga ccctggctgg ctgtgcactg 31440
aagtgtatat gacaataaag tagtaaatct caatgtattt ttttttttat gtattttaaa 31500
taggcctata ggctcatagg ttttttgtcc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 31560
aaattcacag caccccctgt tcaaaattac ttcccgcggc cctgagaaga gccaaagaca 31620
ggaggagaaa gaacagaagt agacagagaa agaatcacct acagacacac agaggacaca 31680
gatgtattgt aattgtggaa gagaatatat taatgtaaag aaggtttaaa tgtggttaag 31740
atattggtgt tcagaatagc tgaatgatgg aagacaatat tatgatcaag tgtattaatt 31800
aaaaaaagtg gatttttgca aaccaggaag gagttgatgg aaattgattg atggaagcta 31860
aaactgaata gtaaaaatga aagtgtgact cactaatata agtgatgaag ttcaaatatc 31920
tgttatgccc ctcttgtttg gtttgtaccc taaagacgca tatgtaaaca tacagtattt 31980
taaaacatta taaagtaata ccaaaattaa gctcctgctt tcccttcaga gtctttgaat 32040
atccaaagat ctaaagaaaa cccaggagaa agaaattaat gaagctttaa tctctttaaa 32100
actgtgatta taattttttt ttccctttta agattagaag tcaagaagta tcagtctgat 32160
atctaaatta taagcatgtt ttttgagata ttaaatgggc tttagggtgc aacaaaactt 32220
tacatactgt atacaacaaa acatatgtac acacattttg catcttttct cagaaagtga 32280
agcatattca ctgatttgga tggcacacac acacacacac acatacacac acacacagac 32340
acacacacac acacacacac acatataaac tctagcagtg tagttcatgc atggtgtgaa 32400
atgaatccca gacttcttcc acactggcac tgggacggtt ttgtcacaac actagtccaa 32460
aaaaagtaac ttttgatttg ctttctgctt caatgttccc ccacggcatc caacggaaga 32520
cggaggagga attgggggcc tttagcagtg cgcagcacaa acagagcaga aaaatgagag 32580
agacagagag aaagaaggct ctgcaattaa aagaagtttg ctgagaagcc tgggaggctc 32640
attcatcata cccaaaacaa cgcaggcatt ctggcccgta gagtgagaca caaacaccac 32700
cgcatcatgt tcttcatttt aaagcaaacg tgtttccaca agcaccttat ttataaagaa 32760
ctctgtctct ctcaggatgt tctgggaaga aatgagctgt ttgtgtgtgt tctactctga 32820
ttaatcttcc tctgtttcct catttattat ttggtggtac agcttttgtg cttcccagga 32880
gataaattat gtctggattt taaggtattt attcataaat aaatgaccat attaagagat 32940
gaattacatt agcaatattt aatatgcatg tggtccagat cttaaatgtg accgtttcct 33000
tgtttaaaag ttgtacccct aaataaatga atattgcttt aaagttgcac tacagaagag 33060
attcaaactg aacaaatcaa catgtatacc tcaaaccatc tgatttatcc ttctgcagag 33120
gagcagtgcc aaagcatgac ccatgtaaag aaaaaagttt gttattttac atttcaaaca 33180
gagaagaggg caaagtttca tagcgcatat ttaaaagaaa atggtttaaa acaaacattc 33240
acatgaaaac atatccataa taataaagat aataaagcag cttaattcac acggagcatc 33300
gcctcatgat tgttgaaatg ttgagatcac atgaccacat taccttttct tgttatcaaa 33360
cctttgctta tggaataaat tagtcatggc ttactatatg aattgggtat ttttataatg 33420
cgtaatgaac atttttgttc atgctttatt ctatctgtat ccatgccact aggtgtcggt 33480
atatttcggg aaaactagca aatcaattag aaactttaag cagaactgca aaattttaac 33540
tacataagaa aataagtatt gcaagtttct taagtcaaat gttaaatgtt gcttgttgtt 33600
ttctatcaac ctctttggat tttttgagca ggaaaatacc tgtactttca gagtaaagtc 33660
tcacactgag aaaattattg atatttcctt gaaaatccat tacgacctac acgtgaaatg 33720
ttttgatgga cttaaagaag tgacctttca gataatattt ttaatctctt aacagctttt 33780
cagtgatctt taaaatcaag aaaactctgg gatgcacggt tactgctcat attgttcaca 33840
gaatgtgtta aatgttcacc agtcaattat agcagaatca aactgtaatt acataatttt 33900
tctgggaaat gggtggcctt ggggcttaag aatcacttaa ttgtcatgaa tgtgcttttc 33960
gttggaaaga catgaggagt gcagcgcatc ctgcatgctt cattaccctc cagcaggcgc 34020
actgtatcct tgcccatgat taaataatca atatcaaagg tcaaacagag tggttatgtg 34080
tcaacctaat gaaagtctaa tgacagtcat ttgcagtcca tgctggacga cccgggtttt 34140
gatcagaatg aggaatttga aagcagaacc aaactgtttt tttttttttt ttttttatgg 34200
taatgtagag tgattatttt ttaaatcatg gccaattaat tgagtacaca gctgtggaag 34260
gccaaaaaaa aacatgattt tgtatgtatg aagagatgag acatgataat ttagatgtgt 34320
catctttcta caagatcaaa ctgtccgcaa ataagaattg attatcaata cacaataaga 34380
cccaaacaat acaacaactt cagcaagctg cgaggcttgc attctctgat tgaccaactc 34440
attcacactt aatagtgttt ggtgaagttc tcgatctcat ttccatttat aattgacatc 34500
tcattcaccg attaataaac aatgtccata aaccaatccg acaaagctat agcaaaatga 34560
aaggttgggt ggtggaaaga caaaatattg aaaaaaataa cacagattca ttttaggctg 34620
agtaatacca aagtcctttc aggcaagtcg tgccactctg ccgccatctt ggcaatgcct 34680
ccgggaagct atttcagaat aacaagacca gctccttttc taaatgaatg gggagagaac 34740
tgcagaaatg cactttcact ggtcaccgtg acatgaaaac agcatgtata gaaacagcag 34800
tgaaatgtga taaaaatcga ttaaaaatgt tgatgacttt gccccaaaat aaggtttaaa 34860
acgccttttc ccccacaggt tgtacctttt actacgcatg cgcaagggtt cctcaactgt 34920
gcgcctacgt cagtggaacc agacgatagg cttaaatgtt tcccgtcttg actgttaaaa 34980
gcagatgatt ggctttccag cgggaggggc gggacatgtg cacacaaccg ccatctttgc 35040
catcacaggt tttcattata tagttgtatt gaggattggg gaagtggcat gtctcttata 35100
aactgtctct ggtaatacta gctgtcttat ttaatctcat tgttatggct ttctgcattt 35160
aatgcccagc tgcaaacaat tatgacatca acacattgat ggattcatac acacaccaat 35220
tagatcacag gaaagtggtt agccaagtaa catttgtttc tctaatttta ttctatgaac 35280
catgatataa tgcatataaa attaaatgtt tgctccatgg taccggaatt ggcaaatttt 35340
atataatttc aaaaatagct agatattctt gtgattccat ttcctctgct taaacataga 35400
ggaaacaagc cctcataatt acagagtgag gcatgtaaac aggaagggcc agttcagcaa 35460
tagaaacgga tgaatcctga acatttgtat ccttgtttgt ctctcgctta cccagttcca 35520
gatgtatggc agggacaaag gagttcagga agaacatgaa gatgaccacc ccaaggacag 35580
tcagacactt gaccagaagg attttgtcag ttattctgtg ctgtgaaaga ccatgaaaaa 35640
catgtttaga tacaggagac atataaacgt gtcaaatacc tatgatgcca tataaacagt 35700
gtttctcaac tgcatatatc acaatgctaa tcatataaag taaggttagc tttataggtt 35760
aacatttaca agagagaaaa aaaacacatc ttttgttatt gacgtcagat aaggttatgc 35820
atccaattaa actccataaa tagtaattaa caaaaaacac actgccagaa gcggcgtaat 35880
gcatgcactt cggatgagag tcagcacggg aaccgatcaa ggtactcctc tcagaaaatg 35940
cccaaataaa gatcatttta tatgttacat tactattgga gcattggaat cactagacga 36000
gggcttttaa tgaactcatt tttgtgaaaa cctcacattc gaccaaaact tgcgcattgc 36060
aactcatatt gcaagcacgg gtcacaaata tggatggata tttagaaaca aaattataat 36120
cactgtttca tttgttagtc actttgtata aaatcatctg cttagtgaat aaatgaacat 36180
ttaaacactt ctgatgttta tacaatcaca aaatattttt tttttattaa atcagtatca 36240
gctcatagta atatatgaca atttgttatg ataatttgat agcttgtaca atcaaagaaa 36300
aatatggctt taaatgtata aataattatt atgtaattat tgtcccaaat tctggttgtt 36360
ccaaattctg actccactgg aatcaaataa attggtgaag tttcttatca tataataaga 36420
taacatcaga aatataaggc aggtttagca gtgaggttct acacttgatc aaccaaagcc 36480
atgttaatta agctttgatt tacctttttc tgcagctctt gaatattgtg ttcccagttt 36540
ttgtcttcct gtgatatttg cctacgaaaa taaaggaata aaacagaata gagggtgtta 36600
atacatcctt tcagccagca tggacacctg caaatgagta ggagtggtga tttcatgcgg 36660
tcaccccgaa ccttttcaac tcggcatgtg atcctgtaaa tagcttctgt gattattcta 36720
tctgtcatca aagtaaaccc caagcagaac taatcggatt tctttagtta aaagaagcat 36780
ttataataat aataataaat aaataaaaac aggctactgt tgagaacaaa attattctgc 36840
atgattaaaa tttcagctct ctatgagagc ttcagagagc cgacacaatt gagaacaatt 36900
acctactttt ctacaggtta attattgctc attcatcatc ctgggcttct gggtaagtgc 36960
taccgtcaga cacaacaggt gtcatgcaca gggaatggat atattttgga cctaataggg 37020
tgttttcaag tgatctcata ccaagaaaga cactcatctt aataccttat atgcaatatc 37080
aaaataatga aagattctaa ggcttaagaa tgcatctgga gtatactgaa agtgtagact 37140
aatatgtttt attctcatga tacaattata taaaaaaaat tctaatccac atacatccat 37200
ggttttaaag cccactatgt aaggtgtaga cagactgctt gtattttaac caggccgaca 37260
aggaaaagaa cggattgagc atgagtgtgg cacctctgga aggtcttgag cttcttgtgt 37320
aggaggcttt ccagattgag caccttctgc atcagaagac acttgacggc cgtctcctct 37380
cggctggcag ggttaatgcg atgggctgtc tgcctccaca ccagaatctc atgcttcagt 37440
tctgcagggt gacacaaatc gtgacaagat aaagggttca gctgtagaac agacaaacac 37500
gaattaagat aagaatttca aatctaatta tatctacagt ccagaaaaaa attataataa 37560
agaagggata attgggacac tttagttcgc tcatttattc agaatatgtt tagcctaaag 37620
ctttgaaatt tgacctcaaa catctttgaa atgtctgtag tcactatgta ctgcatgccc 37680
attaattgta taacttaatt tggtagacac tgaattcaga caaagcaatg tgaagagttt 37740
ttgtttttta atactgtgac caaatcagac taaaaaacaa tagcaaatcc aattttcaat 37800
gcagcgataa cggtttaaaa taaatgtttg atttgatcaa aaaagctgtc aatatttatc 37860
tgtaatatga aatatttatc gaagttggag tttgtatgta gtttaaaata atgagagtgt 37920
ctgtctcatg aaaaattaca actaaaggtt gttatataat gtaggcaaac aaaacgaata 37980
tatatatata tatatatata tatatatata tatattagat agacagacag acagacagac 38040
agataggagg atgaagtaca agctaggcaa ttatacaaag aatggaaaag taaggaaaga 38100
aaatatattg agaaggaaag aaagcaagag atatgtgaag caagattttt cactagtcct 38160
tcagcatgac tcctcaccat gttatgggga ggctgcttgg aaagcttccc agaggctaat 38220
tgacacagga aaaacatgct gatcacaatc gacagtaatg catcatgccg agggcctgga 38280
aaactgtatc agccgcacag caggtttgat tttttttaaa gcgaggctct gtggggactt 38340
aaggctttac agaattagaa attggactgg tattgagtgg tcaccatcag gccttgtgga 38400
ggtctttggt tccaggcgca gcacccacct ggggaaccgg caagccaatc atttaagttc 38460
ctgttcctgt ttatagagca gagttctaag actctgcatc agctcaacaa cagctagtac 38520
tctctcattg tgttagccac ccaaaagccc aataaacaca gaacaaaggg aaagattggc 38580
attctggaag gtgctagtcc catgctgatg atgtctcaaa gggaaggcaa tcctcacagt 38640
gggtaaatgc caacagtgtg tgagaacata taaagtgtgc ctcctgcctt ctgagaaaga 38700
aattattttt attttattta cttgtctcac accttgtttt atgtcttaaa tgatatgcac 38760
aaaaatatat gaatttatgt aattaaggct ctattattac tagtataaga tcaaagaaaa 38820
tgatgatttg gaaaatggaa acttaaaaaa attatattgc ttccctagct acagcgctgt 38880
ggacagtgat ttattgtttt tattacaaaa aaaaaataat aataataaag tacacaactg 38940
tacacaaatg gcaaattaaa atattattta agttcaatat atttaagttc acagaggaaa 39000
aaattcaaaa atgtccctat agttttaact atttttattt aattttttaa gcctgggggg 39060
gttgacatac attaaatcct gtaaatctaa aatctcacac tctttaaaat tactgttgta 39120
agcaacaagt aacaccctga attaaacatg acattttaaa gcaagtctac gattatttat 39180
ttatttattg gaaaatgtac ttcaataatc tttattttgt ttacaaaaaa caattttcac 39240
agtgtaacaa aaacaagaat ggggtggggg ggggggtgat aatctactag acgccttaat 39300
aatgtcacct gatggttcac tgtttaatgt aaagttctta aaatttccac ttttccacac 39360
agtcttatga tataaaggtc cattcaagca gttttacatg atgaatgaaa gttaagactg 39420
aactcctgct tacattgatc tatacacaag tcaaactttc atacctacta cttttctgtg 39480
acatgtctga tcaacaagca gttcccagtg tcatgctgtt ttacagaatc aaataatgtc 39540
tcaaaagacc tggtttaaat cggaagacca accactgtgt gactcttaga actttcagaa 39600
ggaacacaac ttagaaacgg ctttgtgttt tcctctcatt ctgatttatg ggtatggtga 39660
aagcctctct gggaactcca gagccagatt tcagcctata aatggctgaa atgagtggtt 39720
tattataaag gagctattgt cgtactgtca ggtgtgtgaa ggagagctca ggtgtggagg 39780
tgtatgggag atgtgaggag ttggtctctg tggagcaggg ggagcagctg ctcaagaggc 39840
taatggccat ctgtagagag aagttgacaa ctggaggaag aggactcatc tgattatttt 39900
gtctatttat ttacacaatg aataatgaaa taaaaagacc aaaaaatatt tgactgaggt 39960
taaaaatgat caaaccaagc aaataaaatg aatacattaa aatgttattg taataaagaa 40020
ataattcgct atatttaaat attatagttg ctttgcttac acatcctatt ttgtagcttg 40080
aatacctcaa gggtaagttt acacaaaaaa aaatgaatga atgaatgaat cctttcagca 40140
tttactcatc ctcttggttt tggaccccac tgacttttgt aacataatct gtttagcgca 40200
tagtatatgt gtgtttttca aaggaaagaa agaaagaaag aaagaaagaa agaaagaaag 40260
aaagaaagaa agaaagaaag aaactcatgg aaagactaat ggaggtgaga caacattttg 40320
tcagtgtgaa gtctgtgaag atgaagaaat ttgtttgtcc attaatttta gtggcttgcc 40380
aaaatgggag aaatggtaag aaagtgtata catcctgcct gtgaaagaag agggaaagaa 40440
cagagcgtgc ctggctctca gtggaggtgg tgatgaagcg atgactcccc aggtgagagt 40500
ggtattgacc cgtctatgtc tataatggct ttaaccgcct ttctagctgc gttggcacct 40560
tcacacttgg gctaaatgtg ccctgttcct tcaaaatgtc ataaatatgc aattctttga 40620
cacagcacct attccaagca agcattaccc aacggtggat atcaagatac aagtgcaata 40680
gacacgctga taacagtaca acaataacca tgctctaaca agcaccctgt tagggtgtat 40740
ttttgtagat agcaagaaaa tgttcaatac tgtaaattta aagtaccatt tacaatgtgc 40800
tatctttgct tgtaggaagc tctgggcaga gttttcgagt taatcacctg aactgtaaat 40860
ttgaataatt attcaagaac acactgttcc aggcccaatg attcattagc gctctcgtac 40920
tgtaaataaa taaataaaat acaaatacgt gtgtgtgtgt gtgtgtgtgt gtgcgtttat 40980
actacacagt atgcaacagt tctttctggt cctcgaatct ggttggatga taagagtgcg 41040
atattagagt gataacggaa cggagctcca acaactgttt cactgtttgt aactgtatag 41100
tctcgctata gccagacctt cagactaaat gggccatgct aaccagacaa acactgaccc 41160
ccctgacatg tccttgtctg aaaactgtgc ataagtcaag gttttgagag aggtcatcta 41220
tgaaaggatt tatgtattta atacagacga gttacggctt tcagaacagg ctcatccgat 41280
aagaataatg gaaataacag cctgaagggg acagagagac taaatgcatc aatgtgatca 41340
tcagtggtgg gggaggagga agggtggatg ataaattgat gtattgctga gattctaatc 41400
attcatgaaa gggtaggctg tgcctatccc agtcactggg gctcaaaggc caaatgtaag 41460
gagctttgga taggatatga gatttggtgt aaatagcgta gaatggtgta tgagactcat 41520
tcacataccc atataggaag aactgctgtc aacaagggaa ggtcaagtgt gccctcaaca 41580
actctatggt ttttagaaaa gattgctcat tccttaagat ctaggtcaat ggggttatga 41640
attaattttt cattgcacat gtcagaacaa aagagcttga atcgaaaagg aaggaaagca 41700
gagtggctct gcatacactt gagggtagtt ccgtgtgagt tagggaaaca gagcagaata 41760
aatgaatact cacccacgat ttcgctggat tctttgttgt aaagtttctt attccagtac 41820
agcattctca aaaaaggaaa tgaggtcagc agcaccagac agattcccag gaacatgtaa 41880
cccgtaaagg ccgcgaagtc aatcccctag aggaagaaga gggcgggtta attttcaccc 41940
tttaaaaaat tatgcaatta atttgctgtg gtatttcacg aaatctattc taagcactaa 42000
gtagagatca catccacttt actggctctc catataatgt ggatggaggc cttgattaca 42060
tttcatcaac agaatcatgc atctttatgc atttaaacac ttacataaga tttaaatgag 42120
cacctgcttg tggcacaaat cctcttaaaa tgctcttgac tatttattaa ttttcattca 42180
tatcaagagc acacagccct ctcggctgaa catctagctt cagatgatat tttcttgcct 42240
gtgcagccca ccccatcttt catcataacc agatggcatc acattttcaa atggcagcac 42300
tgatagagat gcgtaaaaca gatccgtgtg gcctgaaatc taatccaaca acttaccatg 42360
aggtatcttt gcttgtttac acggggacct gtgtgtacat aattagtaca aagacattct 42420
acaaagaatt ctatagttct caatatagtt ctatagttct ctctgctttc gtgtttaaat 42480
tgtccttagt gagaattctg taacattaaa taactattta atggaaggct accattgtga 42540
caacttagaa acaatatcat attaacaaaa ggtcaacagg tgttaaataa actgtgcatt 42600
tttcctggac aataataatg gcaaaaaaaa ataaaaaaaa attattgtag ccaagacttt 42660
attttttgta actatacaat ttttttttta aatgggacaa ctaaaccccg tctcctctat 42720
tttgtaaaga aactggcaag ataaaagata attgcatccc ctgctgtagt tcggctcccc 42780
acattgctca agcttggcaa aaacacagga cttcaaggta cttcttagaa atgaaacgaa 42840
aggctagtaa agatgtactg tatgtgtgtg tgttgggggg ggggggggtc actgatgctg 42900
gttttggcat tataacctcc ctaaagcaac tcaaggtact aaatcctcca cccttaaaac 42960
aaaaccacta ttaaatgata aatatgttat tgtattattt gaaaaaacta aaaaatgtaa 43020
atgctagtaa gcaaataaca ggtaaacaac atgtccaatc tcagaagcca gaatgaagac 43080
gtgaagactg gtatacagtg acctctacag gagatgagtg agtgcgagag agaggggcat 43140
tcagaacaca catccatttg tgaactctat aaattcgatt tgtactggcg ttttaaagga 43200
aacagcattg aattattatt tggaattatt taaccacatt ataaagagaa aaatacactc 43260
aaaagacagg gaggcgaaat gaaaggacca atgcaagaca aggggaaacc ccttagatat 43320
atgaaaaagt tcactcaaat attatctcat catttattca tcctcattgc aaaaagtgat 43380
gtctaatttg tgaaaagata aaatcagatt tttttttcag tcaatctgct gatccatata 43440
tacagtacag accaaaagtt tggaaacatt actattttta attcattaat tactactttt 43500
tttgaaagaa gtttcttctg ttcatcaagc ctgcatttat ttgatcaaaa acacagaaaa 43560
aactgtaata ttgtgaaata ttatttcaac ttaaaataat agttttctat ttgaatatgc 43620
ttaaaaacaa attattcctg tgatgcaaag ctgaatttcc agcatcatta ctccatttat 43680
aaacagttct gctgtctaat atatttgatg aataaaaggt taaaaagaac tgcatttatt 43740
caaaataaac atttaaaaat tctaataata tatattctaa taatatattt tctttactat 43800
cactttttat taatttaaca catccttgct gaaaaaagta ttgattttat aaaaaagaaa 43860
gaaagaaaaa aattactgac cagtagtgta tattgttatt acaaaatatt tatattttaa 43920
aaacatagct tcttttttta ttttttattc atcaagtatc ctaaataagt atcacatgtt 43980
ctaaaaaaaa aaaaaaagtt aaaaattaaa aaatatatat atattcacaa atcaacctga 44040
tcaggttctt gaattctaaa ggtctggaat aacagacata ataagatggt gagcgaatga 44100
taatgaattt tatcacttta agattcaagt aaagactaat atattgaaag attcaggaaa 44160
atacaaatat cattattagt ttaaaatgaa ccagccttgg gatcatttaa ttttaaaata 44220
atttaggaat tgtgcgatgc atctaaaagt caaaagtatc actctattgt ctgaacctac 44280
tgaaaataag atccttaaca tccttataca gacttattgg ggcaagctgg gctagtgggg 44340
atctgtcaat aacatttcat taaagcggtt ctctgctttt attcctcatg gatttcctgc 44400
gctgttgagc tgtatgccct gtcatatgga gtagatgcat aagtcctcat tactcagcaa 44460
tgcagctgca gacaataggc agtgtttggg gatttctctt tgtagattct cttgttgtgt 44520
cccgaaggca ggcatgtctt gataatgact tagacatagg gtgtaaataa gacctcccct 44580
tactccattt ctgttgtcac tgtcccactt ttagcagcca agaaagtaac ttcataaagc 44640
aatgagaaga gggaatgaga aatcactatt caaaaagacc ttcactgttg gcgctagctg 44700
attagagagc agtcaggggc cacggtcaaa ccagagtctg ccgaagccgg tctgcctggg 44760
gccaggagaa gcactgattg gcagctgaga tttctggaag tgtgactgaa gacccagcag 44820
atgccagaga gtaggcacag ggtctatgag atgtctcctc agcgaccctg aaacactcct 44880
tctgcccagg ctcaaatatc tgatctacag agagctccac agatggatgc ttgactgacc 44940
aaatggcaac atccctgctg tagaaatcct gtcgagaccg aaggggggcc catttcgact 45000
cgcacggccc aaacaaacag agaaacacaa acaaataaac aaagaggcca caagtacaag 45060
atgttccgtc atgactgact gctgccgggg aaatgtggga cagacagggt tcacacgttc 45120
agggaaaacc tggaaacttt ggaggttata aaatttgtga gttctaggcc tggataagtc 45180
agagatatta agaaaatcat aaatcatttc aaccgatttt ctatcatcta ccactcattt 45240
gctctctaac aatcatttga taaaactatg gaaaacctaa taataaaaaa agtttgaatt 45300
tggtcattca aactgtgatt tttgtttttt taaaaaggag tgatggcaca cattttagtg 45360
ttacaaataa atgttgtttt atggtatgaa aaaaaaagta ttaaggtttg atattaaaga 45420
ctggagttaa attgcttgaa tattctgctt tgccatgaaa ggaatatatt ttattttaaa 45480
atataataaa acagaaaaca attattttaa ataaataaaa aaatctgtat ttataatcaa 45540
ataaatgcag ccttggtaag cataaaagac ttctttcaaa accatcatac agattacatt 45600
atttgctttt tgtaagtcaa ggtagtgcat aaaatctttt gaagctgtgg attagtaaag 45660
cacagtgctt tttattaagc tgtatggtac cgtgtcatcc ctctatttgt atggcagagc 45720
ttgcattcag aatcaagagg atctaaagat cttgaggctg attggagctt aataaacaga 45780
ttaagtgact gctggagaag gtggcttcac tatagactca aattaaatcc ttggctataa 45840
acaagcaaac agacatgagt cacacaaaaa tgcaaatact cattcattta catacagagc 45900
tgaaaacaac agtataccca gaaagagtca agctagttta aagtctgcaa gtaaaataaa 45960
atataataaa aaaatgtcag gtacagaaat gcatttatat ttttagaaaa atcgcctaaa 46020
gaacttttaa gcttatacaa aggatcagta aactacatta caccacttta tgtgcacaca 46080
catacacacc ataaaagcac ctgtttgaac cagtttaaaa atagttttgg atcagtcatt 46140
cacggaaagc ccagagtttc atcgactcct acctctattg catcaggaac ccgagtcctc 46200
cgacacatgc gtagacatgt gtaaagcaga aaagtgtttc atcataaaac agggaatctc 46260
ttagtaaact ggtattttat gtgactaact ttaagaccca gctaaatagg tcccaaatca 46320
atgcacacag cagtcaacaa atgagcaagt attgaactgc atatatgtat gtgtgtgtca 46380
ttttttgcac atgaagctgt atctccattc atcatctgca tgttgtcaac acaaacagaa 46440
gccctctcaa atataaacaa atctggcccg tgtatcacag agataacaca aaccactgca 46500
tccatgtcaa taattacagc agatgcaatc tctccctgcg gaacagaatt gatgaatctg 46560
tccagtactt cacacactcc tctgtgtatg cgctacagga gcatatttat cactgaacgt 46620
cccgatggaa agcaaaaatg atgtttataa agttgtacat ttagagcagg ggggtcttca 46680
gtacgtttga tgggttccac cctccagaga tttaggcctg tcagaaatgc aagtttatgg 46740
atattggggt tttttgaaac gtcccactgt caattgtagc ccagcaggaa gggaccttga 46800
tgtggaaaat ataacttgag cgtgattacc gctgcatcat cctgtgcaac agccggtttg 46860
acaggcaagg acggtgtatc tactgagcca caaatgaact caaaccccac agcgatttca 46920
gctctgaaag ccagctgaag aaacaatcat ttaaaccagg cccctttctg tcgctgatgg 46980
aagggtgtga ggaataacta aattaaaaac tgtgatggca gctattctca tgaaatattt 47040
acgttgccct tgttgatggg ttttaatggg tttaatgacc ttttttttta cagagaagta 47100
aaaaaaaaac ttcttacagt aagacttgga ttaaaaatga atggaaaata cttctacagc 47160
atttgttgat cactttgttg ctattaacaa aatattaatt aaaagtgaat acgcaattct 47220
ttaactatta catacaataa gaaaacgttt taagtccgct ttcctttttt ttttttttgc 47280
acatttttat acgtttatga aatatgaggt ggttttcgtc caattttttt aaaactaata 47340
atatcacttt cattttcatc ccttttacta attaaatgtc tgtcattttg tgtgtattgt 47400
gaattttata tctttcatat cccaatttct acaaatcttt gtgaaatgta aagagtacaa 47460
gacaattgaa aatggccagc tcactgctta ctaatttacc aaataattta ataatattaa 47520
actataaaaa cactgaaatg ccaagccagc tgcagcttga tatagctaaa aagccatgaa 47580
attgcataaa aagaggatag tttgttctaa acaaattctt tctgtttaag ttagtttaaa 47640
agttccaagg tctcctttcc aaaatgtgtt tccttttttc aataaaattt tattttaagg 47700
atttttcata gtgcaacaca aacaaacaac acggttgcag acttcacata cactatcgaa 47760
gaaaaaaaaa tacataaaaa caaataaata ataaaaataa aataaaaaca ataaaaatac 47820
atgtgtgtgc aatacctttt aaattaaata caggattagt gctgcaaaat attaagatta 47880
gtttttctaa atagccaaga aaggatccct aggcagcaca taacatttca atggacatag 47940
acctcacaaa tcggagtctc caaaatgtgt tttctaacca gtttttgaca ataattctga 48000
caacaatatt aacagaattt atgcgctaat taaaaaaaaa cattaaaggg gggggggggg 48060
tgaaatgctc attttcactc aatatcctgt taatcttgag tacctataga gtagtactgc 48120
atccttcata actccaaaaa gtctttagtt ttattatatt cataagagaa agatagtctg 48180
taccgatttt tcccagaaaa acacgaccgg ctggaggcgt gacgtgtggg cggagctaaa 48240
gaatcacgag cgccagtagg cttttgcgtt gagagcgttt ggaagctgtg acaccgtgag 48300
gacaaaacca accaaaacaa accatggcta acagccagat tcagtgtata tttatgatcc 48360
agaggctgaa atttaagaag agcagcatca gcaacaacgt atctatgtgg tatgtactga 48420
aactgtatat attggcttag cggttttgga aaatgactaa gttccacttt gtcgtctttt 48480
tttttttttt tttttttttt ttttttaagc tgtacatgtg gaaagtgcag tttgatgaca 48540
acatcgcatg ttgtttactt gatgtgctta cgcgccgata gctaagttaa gttaataacc 48600
gcatgcggtt ccaacacacg atcgtgaccc tttttcgttg ggactgcatt atccttaaag 48660
gtcccatgac atggattatt tccttttctt taaatgcttt ttaatgtttc cttaggtgta 48720
tttaaatttt tagtatgatt tttgcattta aaatttagaa ataaaaagca tttttatatc 48780
ctgacattag ccctctggct tgaatgctct gtttgaaggg gcgtgtctgc tgtgagactc 48840
cgagtaaacc acaactgttg tgattggctg acatctttgc attcgaaatg catattacat 48900
gtgaaacccc tctcaaatat atatatatat atattactat tacagctgtc gagattaacg 48960
aatcgtggaa gtgttgatta tataattatt tttccgatct tttccccatc acatgaaagg 49020
ctgcagtgat gagcattgag tagacagagt ctgtttatcg cgtggatgca gtgatctcgt 49080
cattattgca acacgttatc tcacaaaatg ctttcaccac agctaacagc aaacacatga 49140
atacagtaag agctccgttg tgcagcataa cagcgtcatt cattgtaacg gcagtttggg 49200
caagtgtgca gatatactcg cgatgtgtaa cagctccgga aaaaagcgag cgttctttga 49260
tcgctctctg tagttaaatc acaatttaaa taacagattt gtttcatgct actaagagaa 49320
acaacgtgaa gttgatcgtt tagtcactgg cttgattcac tgattcatca gtattaaaca 49380
atttagaaag aaagtcggtg tgaacttgaa tgattagcta cacatcagaa atcactgatc 49440
acagatcagg cattaatgaa cactgttact cactgtttgt gccggtgctg tcgaatccat 49500
atcataaaag tctgtttgta acgactgtgc tgacattgcg actgaattat atgtaaatat 49560
ttgggcgggc aaagcagaga aaggggaggt aacaattctc gttgcaacgt cacaacgagg 49620
agattcaaga tcagcccgtt tgagcttcca ttttctcaaa ggcagagaaa gatagaaaaa 49680
tctcaattta caccgattca aatttctaga aacttgggga ccatatacgg gctaggggaa 49740
ctcataataa acttaaaaaa cctcagaaag tgaaattttc atgtcatagg acctttaaga 49800
aataaacgat gtgcaaatcc gtcgtcaaac tgggccttgt ttgtaaaaca agcatcttcg 49860
aaatgcaggg gaacaaacac aaacacttgc acaactccgt tgatgctctg taaaaataaa 49920
ctccatccac tggtccctta atgctgtttc tcttttggta atctgtgcag ggttgtcttg 49980
ccctggcaac caaaaacaca cttcttttgt gacatttcgc aacgctctcg ctctggtcag 50040
tgattgtctg tgctcagcct ctcagtgctc tgctatacgg gagcgcgcgc tcttccggca 50100
gaagtgccct taagacccat ataaggaaat tccgctccat ctaacgtcac acagagccat 50160
actcgaaaaa aactttccga aacttgtgac aaaccggaag tagtattttt ggaacagaaa 50220
tactccttca aacgtacaac ttaatttttg aaactttgtc catgtttaga atgggaatcc 50280
aactctttaa cagtgtaaaa aactcagtat gcatgaaata gcatttcacc acccaacccc 50340
ccccccccat aaaatatagt gtcgaccctt gtgaattttt tgattcatgt gaaaatgagc 50400
cctaactact gttgatctat tgctatgatg acttctgaaa aaaatcatgt gcattgccaa 50460
actcctcttt ttacctttgc tagacccttc aagtcaccct tgagattctc cctttaaaac 50520
gcacttaaaa tgtgaagcag cacttgatta aaacagctaa tttaatgtgc ttcacacact 50580
aattcatccg tctctgtcag aaagtgtgat ggtgctggaa atcagtttcg ctgacaagat 50640
gtttatatga catcagaatt tatggctctg aatggattga ggattttagg catatagttg 50700
ttcttttgcc gtgtaccctt ttaaatagac tgtcagaaaa agatggatct cctattctgt 50760
tatagccacc ccttttcccc tccctttctt ttttgcactg atactcacac acacacacac 50820
ggttctgtgt cttagccatt gtctctgtgg tagtgtgtga cagaagagct gcagggtaga 50880
gtggctctaa agagagcatc tttaatcagc atccagagcc ggagatgaaa gagctctatc 50940
tcgtccactg tgtctcattc agggcttcag ctggacactt acctgtacat gtaggctact 51000
tactgacaca cacttcgacc atatacacta acacatacac tagcatacat gcttttatgg 51060
gagaagaact tgccgtcgta aatgattcat aacttacaga ttctcctttc taaaaattct 51120
actgagtttc ataccgttta gctctgacta tattcacaaa ttgcatgtaa ataaatgtgc 51180
ttctgaattt gagggaaaag cacctcttaa gcaattagac catacatgaa acaaataatt 51240
aagcaagcta ctaaacactg gtgatttaaa gatgtgaaat attatgtcat catcatcata 51300
tccagtcacc ttcagtaact gttgattttg aaagtctgga caaaaatatt tgtgatatgt 51360
ctttgtggtt ttcatgttta ttcatgttcg ttcatgaaat gcagggattc ccaatcagtt 51420
ctctgatatt ggttaatgga cacaatgaca tgcaggtaaa caaataaaag cataatgttt 51480
aaaatattta gttttcttct tttttatcaa ctcacaaagc cactgcagtt attacattaa 51540
gcctagtttg gtaaaccatt atgtaatgtt taatgcattt ttttgtgttg tttttataag 51600
aataaaaata aatatatata tagatagtag atagatagaa tttagacctg aagtatactt 51660
gcaaacgctc aactaaagca ttgcgagcac agtcccattg aacatattaa atgtgtgttc 51720
ttacacatgg agactgataa caaatctcat gggatgatag atctagcttc aaatgtcttc 51780
gctattgaat cggatttgtt attattcagg taaacatact tatgagatct aacctgctca 51840
gcaacattct cttcaaactg ccccttctct gatttaaaag agaaaactag ctttagaaac 51900
aaacagttta tgctaatgcc agcttgcggc aatgccaaga acgcagagaa tgcagagaac 51960
gcatacttct gttgtgttat gaagtgcact caaagggtta gctgttcata tccataatcc 52020
taaataagag ctataaaaca actaacacga ctacaaaaag acaaactggc agacactcaa 52080
atacacacag aataagctcc aagacatata ctgtgaattt agccatacaa ccgatgaggt 52140
caaacatgaa cattttaatc aagcacaaac cggggtcaca ctgttctgtc tcctccatta 52200
aagtgaataa taaatcacaa aatgttccct cgccttttca tatcaagcca atattacaca 52260
agcctcaaag aagaccacac aagactctgt gctttgaggt cacatcataa acctggagat 52320
tattcagccc gcctgtgacc ttgtccaacc ggcaggacgg aactttaaat tgtgttttcc 52380
tgcgagttag ggtttgattg aaacagtttg ctcatagact ttgtagttgt acaacgaaaa 52440
aagaaagttc tgtgattatg ttaggaaagt acacgccgat gttgcagacc tatattttgt 52500
aatcacttgc atccacaggc attgcttcgt tgtaccttca acagcatcaa gtatcacaca 52560
ataagatctt tttcacacag tgcataatca agtaggagtg tcacaatata ctgatatcaa 52620
tgagaaccat ttaaaaatga aatactgata acacgttaat agtacaaata cataatatca 52680
taactaatcc agcgccaata actggttgac acttccaaca tagtaggtgg ctgtgttgca 52740
gccaaacact aatcctaacc ctaaccatta attaatacta ctcagtactt aaatgtataa 52800
ttacattgta acaagaacac cttaaaataa agtgtaacct atagatttta tatatacagt 52860
atatctatat gtaatagtgt tatctatagt ctatagtgtt cctgtagctc aattggtaga 52920
gcactgcttt atcaagctca aggttggggg ttcgattccc cgggaacaca tgataggtca 52980
aaatttatat tctgaatgca ctgtaagtca ctttggataa aagcgtctgc taaatgcata 53040
aattcaattt taatttaatc tgatttacat taataagaat tagatattta cactcaaatg 53100
gtaatatgac aaataaaact gcctaaatga ccttgatttt ctgatgtgca atgtgtcaat 53160
accttacatg ctgtttctgc atagtatgtg aaacaaggga gatactgtga gtaacaagtc 53220
tattgcagca aaacatccca taaaccttta gtcgaaaaac tgtctcagag tttgtacaca 53280
atgattgtac atgtttgcca tttagttttt actaaagtta aaagatttca actctgctga 53340
gagagagata gaaagagagc aagagagata gagagagaga gtttggcaga gcgtaactaa 53400
agctggcaag aagtattcct acataattaa tagtctgagg tgtaagacag gatgccatgg 53460
tgttttagcc ttgagtagat agtgacagcg tgttttggca caaggctatc attctatgcc 53520
acatgcttgt gtctgtgtgt ttttgtttat ttgtgcagtc atgtataatt tgtccaacaa 53580
gttccccgag acattctcaa caggcacacg acagtagcac aatatccttt cacccgtgaa 53640
taacccagca tcaaataaga acggtgggaa ttaatgacat acttttttcc gcagatcctg 53700
attggatacg atgatgacat tgggtggatc tccaacagct gtggcagctc ctccgatgtt 53760
agtgaagatg acctcggcaa tcaggacgtg cctggggtcc agattgagca cttcacataa 53820
cctaatgtac ggaagacatt acaaaacttg attagaactg ttgttcctgg aacaccaatg 53880
caatgctcta agaaagttaa atgctcatcc atcctacttc tatgattttt gtatggtaga 53940
acataaacca tgcaaaaaaa cacacagaac accttccact tatacaaaaa ggttccgaaa 54000
aatatttcaa atatatatat tctgtactaa gtaaaacatt ttagtactac ttgagcacaa 54060
tgcacactga tgaggaatgc atgatctttg aataaaatat taatataaat cgaataatac 54120
actgtatact gtattagtct ttaaatgtaa gaaatttaaa gtgtaactga agtatacttg 54180
caatagctcc actttagcac aatcaattat acttcagtgc atctttagtt ggacttcagc 54240
actacttacg cacaagtgca ttaagtacaa aattagttgt ttcaatttaa cagactttaa 54300
gtatatcagt ttagtgaact aaaagtacag ttgcagggta attttattaa gtacttaaat 54360
aatgtaaatg tatttgtagt aataataaat gcatttcaag tacattttag tatacctatt 54420
ttgcactagg gttaacaacc aatgtggttg ttaaccctag tgcaaaatag gtatactaaa 54480
atgttgagca gcaacatggc aaccaccaca atgtcctagc attgtagctt ttgtagtttt 54540
acacagacta acatgtttta ccataaaata tggaaaggtg aggacatgat tcttcagcag 54600
caaaacttta agctgagatt ttcaagcaaa tctaaagata aatcagtttc cctgctaaat 54660
tggcataaaa aaaactcttg cacaagcaaa tagcctgtca acgaaaagct gaactctcta 54720
atttctcaaa ttcgttcttt aacgtgtgtg tgtgtgtgtg tgtactgtgt ctttgaaccc 54780
tgaaaccccc gaaggtgttt gaagatgcaa ttggtgatgc ataatcaaaa aaaggagtca 54840
tttctcacta gcagtgccat gaaaatgctg aggcagcgta taacttttta atggctactt 54900
gtgtggtcgg ataaaataaa tctatatttc acaagagatt tacttttaat gtctacataa 54960
gatgataaga atttgatgga tgaattttgc atgaggataa aaaaaaaaaa aaagagtatc 55020
cttgttgaaa aaatacatgc tttgttggct ctttttttaa gcagggatga gacatgaaac 55080
aatactacat gacgcctaat tgcttcatat cacatgtagg gtgtcctaaa catagctaaa 55140
caaacgatat gtaaatgatg ctgtacatca ggatataaaa catataaatg acttaaaatc 55200
acaaatataa tgtgcacagg caccaataaa tcacattgag ggacaacgtg caacggtgaa 55260
aagatggaag aaaataagct caaatggagc tgaaaagagc aatgaggtgg gatgtttata 55320
gcatggagac atgagttatt gaatcctcat ataaatctaa gcacagacta acagagaaaa 55380
tcttgtcagc agaaaagcca aggccttttt tttttttttt tttttttttt gttgttgtag 55440
cagttcagct taacaaactt ctttacaaag tttactcttt attagagaaa tgttccaagt 55500
tcaatgcaaa ttaagctcta ttgatagtat ctgtggcatg ctgtcactta ccaaagaaat 55560
ggatttgtcc ctcagttcat aaaaataaag gaaagtcacg ttttacagca aagcacttac 55620
aacgaatgtc tattgggaaa ggcattctgg aggttttctg aggagtctca catgttgtgg 55680
cttcaacctc agaacattgt attttaaagt ttattccagt gtgattactt gtcacataga 55740
cttgtattac taaacagggt tgaaaaaaga agtcaaaaga gatattaaga gagaaacaga 55800
ctctgttcca ggaagagaga ccattacctg attgtaacag gggtgaagag catcatggtt 55860
gtgacgttat caagaaaggc tgacagaacg gccgcaatta ggcacagaat cataatcatg 55920
ggccacactc ttcctcgtga taactgatac gcctgtgtgg agacatagag aacactgttg 55980
ggaatccttg gtttacaaag gtttgatttt tctcgtaaca tctcattaat gaaaactaac 56040
tgggtcaaaa ataaattaaa ccccaaaatc gcttgccttt gtttatgaac ataaaaaaaa 56100
aaaaaaaatc atgtgttcaa agcattcttc agtggaatgg ggagatggat ttaacagtgc 56160
ctcaaagaca gagaatcaag agcagtcctc tgagagggtc tcagaacaca atgttcaaaa 56220
gtgaaattta atgaggaatt cagtctaaaa actgacacgg atctgtagtg tttttgctca 56280
ttcgtgcctg aaaagaaaag aatacaaaaa aaaaaaagac ctccaacttt aagagcctgt 56340
cgctatggag acattatcag gctgtctgga atcatactaa tcaagtggta atgccggggt 56400
gttgtaaccc acctattatg tcactgcttc ctgactaaaa aaagatgcta actgaaaaaa 56460
aaaaaaaaaa cagagcaaag gcccgttcac accaaggatg ataactatta cattaacaat 56520
aaagaaagaa taggggatcc tatatcacaa ctgtgaaagg cacaaaggaa cgatagcatt 56580
ttttcttcca gccgatgaat gctgaaaaca ttgacagctg atcaggaggg ccacagctct 56640
gcacagttta gctccaaccc tgagcaggat tactaaaaac ttccaagcag gtgtgagttg 56700
gagctggttg gaactaaact ctgcagagct gaggccctcc agtcatggag tttgagacta 56760
ctatattatg ccctttttac aatatgtaat ataactcatg tttccccaga atgtgtctgt 56820
gaattgcctg ctcaaaatac cccacagatc atttattata tcattttgaa aaagcatttt 56880
tgagtggaag cagaaacatg cttttttttg tgcatatctc tttaaatgca aatgagctgc 56940
tgctgctccc caccccccat tttccagaat agagcgctgc ctttacagct tattcttcag 57000
attcttcaga tacattcagt ttgtttttgg ttttgactat catgtctatc gtgcagaagt 57060
tatgtgtttt aaacaatatt agtttaaact tctgatatag gggtttctga gcacatgttt 57120
ccaaagcaca tgcacagata gcggctttca aatggcatgt gagtattaaa ctaagttctc 57180
tttcatgtct tattgcacat aaactctcaa atacacacag gtttatgttt gaaaacacac 57240
aagttgcaaa aactgtaggt tatgtctgtg aaggttaaca gccagaaaga aattgcatgt 57300
ttatattaga tctgtgtggc agcagcataa tacatagtaa ataaatcaat aaatccactg 57360
ctctcttgtc tcctctaaat agtgttctgt gctcgtcagt gcagccaaag acagaacaat 57420
tagcatgctt tgctcgaact gtttcatggc attagctgtt gggggaaaca tgcaaattaa 57480
ggagcagtaa tattattaat aaagggtcat atgtaatttt ttcacaagct tgctgggaaa 57540
ggcgtccaat tggtagatgc actggagacc cgattgtggc acttaaacaa aaaaaaaaat 57600
cagattttca tgatatgtca cctttaaagc cgcagatgac aacagcagtg cacatttata 57660
ataaacagaa cattaccgtg cgttggtgtg gacactaata ttgttatcgt tacagttatc 57720
gtccttcatg tatacatgcc ttaaccacac aagaccacac acacggatag aataagcttg 57780
atttttttat ttcaaggcaa aatactttat gctgtcttga gatgatgttc aatcaaaagg 57840
gttgtttgta tggcaatatt tgaaattgtg gaacatgtcc tcgtccagaa ccctcttaat 57900
attcataaat ggaatgagag gacataagca tgtgccttca taatgtccag ggcacatcca 57960
taatgttcca acaggtcttt tacaacagtc cccagaatcc ctgaaaataa ggactgcgat 58020
atttatccaa tgaagctcat cctaagattt atttttaggc tttcattaaa tctaacccat 58080
tttcttcatg atttataaac gtttgcgtca tttaacaaag attcgttcca tctgattcct 58140
tttcacatct ctattggggc tcgatatttc cccataaatt tcatatataa aacatttgtg 58200
gggttctcat cacttagcat gagagtgaat gactttcagg gcggctatcg taatagctct 58260
gctgcttttc cccaaagctt actgggaaaa atagcatgat gggattacag agactaaata 58320
aaaaataggg acatcaataa tgtaaaatga aagaatatca gactgaatca atagcagcag 58380
ttcacatgct acctagttgt ttctgactaa acattagtag ttttatatgt aagtatataa 58440
ggtatataac tgtatataat attacctgta tatgctaagg tgggtgggat agattgagaa 58500
gactaatttt agaaaggata tgatgaaata agtctctcag aaaccaagac tcaccttcac 58560
tgcacagtaa tcaaagaaac cggtctcaga gaatattgcc accagtatca tctgaaagta 58620
aatagggtta taagacttga acatttcatg gtttctattt ttagtgctta ctgccacatg 58680
tgtcgctata aaatcacatt atgtctcaaa taccacacgg tctctcactc aatttcatgc 58740
cacatatata cttctctgaa tttgtattta ttttttattt tttttgccct gagatacaga 58800
aacagacagt cttcgaatta tagaaaatca ataaagtgaa acatcaatat ttctgagttc 58860
attaaagcaa atgtttctaa tgtaaaatgg ctctcagtct ctttgatagt cagtccttaa 58920
aattgacagc tgctatgatt cattctctat catcagtctc tgattttctt ttatgctttt 58980
cctcaaatac tcctacatgt agtcttctgg atgagggctg attgaatgta tttgtttcca 59040
tggagacaga cactgaacaa acagagatct tgaaaagggt ggcacttcag aaataatatt 59100
agagaggctg tgttcttaat gtgtattcat attttttggt cacactgtgt tgcattaaca 59160
tgtaaaatat ggactaataa ctaatgcaga ccaccagcca cacctagcaa acatttcaac 59220
cgaccgtgct gctgcaatgt acagtacatg caacgcaaat aacgccctga ggaattcttt 59280
ctaacagcta gcactactgt aggttaacag cacattaaag aaaggtgccc cactaagtgc 59340
ctgacaggct gagcagcctg agagactgat gtaggttggg gttaagggct ggataagggg 59400
ctttgtcaga ctgtcaagca cttagcaggg caactttctc caacaggaag gttaaagcat 59460
ctcattacac catgtttaat gctctctgaa agaattcaat tactagtttt tatctgaaga 59520
aaacatgatg tcggttgcga gatttggcat ttgtaattcc atctgtggta ttttattaca 59580
aagttataag tccagtttca tctaaatgta tctgcacaca tcttcccaac atatatggat 59640
atatgttcac agtacacaca gagcaccagt tttactttta tcatttgaaa agccctgctg 59700
tgagtttata tttaatatat ttctttggaa ccctcctgct gatgttaacg gagtaaaaaa 59760
gttctggagc gcttctagac ctggtagaaa tatgcttacc attccaaaca gcaatgcgag 59820
agtttcatag tcgatccatt ctacaacagt catcagactc ggcctctaca ggaaaaagac 59880
agtgagatca aatagtcatc atctgtttat ctccttcctc agatgcaaaa ggacattttc 59940
acatcctagt cttaactggg ttttctgaat tgttgaaata attgcatcaa ttaccatacc 60000
atttaggcct acatactgta ttctgtttac tggatttgaa agtttaaagt ttttagtaaa 60060
aaaaaataaa taaagacatt tgagactaga gagctattgg tctttttaaa gggcactcca 60120
tctatcaaac agacagaagt tcactgagta attttactca tgctcaaata acgtactatc 60180
tccaatttct ggaatacaat aactaatact cacatagcac attagagtaa atcagtgcaa 60240
ttaagttaaa tagtccggtt agttaattgt gtaaatgtca ctgtctttta tcatatactg 60300
tatatatata tatatatata tatatatata tatatatata ctctgaagct catgaactgt 60360
aatttgtaca tactttatac ataatttata cagacttctg cacatgacag aatgttgctt 60420
tgctcataag ctaataaaac acaagaccat cactgcagtt ctcagcatta ataaaatcct 60480
catcagaata gactcttcat cagaaaagaa taaatacatt ctctaaatct tacatctcca 60540
atgaaagcca gtgctgccag agcagccagg gatcctaaca ttgcagccag agtgcggtga 60600
acaatctgca aacacagatg caacattttt actcacaatt taaatactat atattttgga 60660
aatgttatta taaacctggt catatatcaa tgggcacaat gtaacacaaa ctagatttgt 60720
gctatgggct cactaagatg ttctgagtgt ttttggcatg ttgctatgcg gttgccagga 60780
tgttgtaagt ggatgcttac tgccccaatt tctttatcat tgaaagccag tatggttttc 60840
tcactatttt ttcacctgcc aagcaaaaat cataaatctg attgcttaga aaagtaatag 60900
aacaactcat ctcaacaagc tccatgatat gaggtatcac aaaattgtaa tacttgggat 60960
tagggaggtg ttcaaatccc aaaccctttg catcagcaac agtaatagcg atgctttcct 61020
tagcaaacac aattaaatat tgaaaatata agcctgtgta taacagttgt ttttcaacca 61080
atttttcctc attcaaaatg cctattaacc ctctacccca cacttaattt atttttgatc 61140
cacctcattt ctttaaactc attctgcccc ttttatgcac tcttacaatc aaatgataaa 61200
tgccaaatca caaggatata tacgcgtcag tcgacagcgt cttctagatg cctgctcttc 61260
aatcagcctc aggactaaaa gcaccgcctt aaagtgcact gtcagatatc tgcatcttca 61320
gcatctgttt tcctggtgag agcacttgac tggaacacct gaatcaaact ttctctgatg 61380
cacctctttc agaatcatgt gccaagatga agaagtcatt acaagagctt gtaatcagcc 61440
agaagagcca aaaaagggca atgagtacag aacatgttgg gtaaaagcta atgactccag 61500
tctcgaagga gcaagtaatc tgtgtcagtc cgacaacttc cctgaggggg aggaacactt 61560
ggtgcaatgt tgtgattgta agtctaaaac aggtcattaa gataaatggt tgaacactgc 61620
tttctgagca gaattaatca gcaacataaa tatatattgt gctgctttgc ataagaaagt 61680
atcctctgag actaatgttt ctctgttttg tggtttaaac caattactct caattatagg 61740
gtaagaaaca gtttatggct aaatgaaaag tcaaaatgtg cctgtgtggg atgtaatgtt 61800
agttttatac ccaaagcccc ccagtaactg agaaactgca actctagtct aatttaagaa 61860
taatctatca gccattatta aaatgtttac aagatatctg caattagatt gtgaagatgc 61920
attattcatg aatcttttaa ggcatattaa tatttataag catatcatac tgttatatat 61980
ctcagatttt aggttttgcc ctctctcggg gcaattgagt tttagctgtc agagctgctg 62040
atgaaactca ccatctgagc ccttgtaatc aaagtagttt tcagagtgct gattctagat 62100
cagttcggag gattatcact aagctgctat acaatgcaga taggaagaac aggcccaggt 62160
cgataaaaca aatgctgctt ccttatgtac aatggagtcc aaatgtctga gaacacaaac 62220
ttctgcggaa tctctaatgc tattcaagtc tattttaact tggaagtaaa caaagttttg 62280
gaagatttta aacataaaat gaagaaatat ttaggggggg ggggggggtt aaatgctcgt 62340
tttcactcaa tatcctgtta atcttgagta cctatagagt agtactgcat ccttcataac 62400
tccaaaaagt ctttagtttt attatattca ttagagaaac aaagtctgta ccgatttttc 62460
ccggaaaaac acgaccggct ggaggcgtga cgtgtgggcg gagctaaaga atcacgagcg 62520
cgaataggct tttgcgttga gagcgtttgg aagctgtgac attaccttga ggaaaaaaac 62580
atcatccaaa acaaaccatg gcttacagtc agattcagcc gtttatttat gatccagaat 62640
cagatcccga ggctgaaact gaacgagagc agcagcagca acgactcgct ccgagcgggg 62700
ctcgaacccg gttctccggc atgggagggg acgcactaac aaggaggcag agacatttta 62760
agcagtttta ccaacacacg atcgtgaccc tttttcgttg ggattgcatc atccttaaga 62820
aataaacgat acgcaaatcc gtcgtcaaac tgaaccttgt ttgtaaaaca agcatcttcg 62880
aaatgcaggg aacaaacaca aacacttgca caactccgtt gatgctctgt aaaaataaac 62940
tccatccact ggtcccttaa tgctgttttt tctttggtaa tctgtgcagg gttgtcttgc 63000
cctggcaacc aaaaacactc catttgtgac atttcgcgac gcttttgctc tgatcagtga 63060
ttgtctgtgc acagcctctc tctgctctgc tatatgggag cgcgcgctct tccgggagaa 63120
gtgccctcag gacccatata aggaaattcc gctccatcta acatcacaca gagccatact 63180
cgaaaaaaac tttttcgaaa cttgtgacaa accggaagga gtatttttgg aacagaaata 63240
ctccttcaaa cgtacaactt aatttttgaa actttgtcca tgtttagcat gggaatccaa 63300
ctcttcaaca gtgtataaaa ctcagtatgc atgaaatagc atttcacccc ccctttaaga 63360
ttctgcactt tggttgctaa ttaaaccagc cgtgtgaact actgtgtaaa acgtttatta 63420
tgacgacaga tattcttact tccactgaat gacaagactc ttttgaagat cgcaaattat 63480
gctcaataat atgatcattc attttcataa aaatctctgg tgatgctgtc aacacataag 63540
acttcattta aaagtttacc tttttcccac taaaattgct atgctgataa tgtaatgtat 63600
aaatcgatgt cgaataattg tattccattt ttttaatata tatatttagt actgttgtat 63660
atcatctgat tcagcagtct attaaaagct gattatgaag gcacaatctg ggcaactgca 63720
ctttccttct ggcacacaca catttatttg gctacatcat atgctgttta gatcaataca 63780
tgaaaaacag cgatatttta attataattg gactgagtaa tggtggctgt atttcctagt 63840
attaaaatca agatcaaaaa gctagcgata aattcagact aagaatgact gtatgagcaa 63900
gtgttgtttt ggtgttatgt tacttctagt gaaatgtcat gctgtgttat gtgtgagata 63960
ttcatcatta aaaatggaca gactgcactc agttggacag caaagttact gtgtttttcc 64020
aacacttttt gatgatttct aaaaagcctg ggaactagtt catatacatc tcatagttga 64080
ctgaagttgt aatattttct cttaattaaa gttgtaatgt tttctcacat ccagaaaatt 64140
tttatatata atataatgca gtcttcaaca atgggattat ctgatgaatc tcatctgtaa 64200
tccattctta gatactggaa gtgttctcac tgggaaggga tttgggggaa acttcttata 64260
aatagatgat cacagaggta acgctcctct attttaaaag cataataaat aaacgaacta 64320
tgactcaccc attcaacata aaatttgttc attagttcac ttttaaaagc attattttta 64380
ttttctcagc tccttgatga cagtgtagcc atagttgtga agcattagta ttaacggtaa 64440
aagtggaaac atgggccccc aaagtctcca ttagcattcc cacaaaggtc taattaaact 64500
cttcgccacg cagcatgctg tccctcctga agacataaat gtaattagga aaggaggtcc 64560
cctctgccct catgtccccc tggagccaca ctaaagcgcc gctttttcgc aaaacgtgtg 64620
cactacaggg agaagaggaa gttaaaagtg tggaggagtg ttttgctgta aggctcttta 64680
aggctctagt tgttccgact gacatgacga acattgtatg aaagtgaaca aaaaagtaaa 64740
taaatatata aaatcagaaa ttaatcattt ttaaggtgaa ttagagtcat aatcaaaaaa 64800
gaccagaaaa ttatgtcttt atatagtcca aaagagacca ctagtgaaaa tgcacctatt 64860
ttgcattctt ttgtcattta catttttaaa tcaactgaaa tgatcatgtt tgagtgaaca 64920
gtttaattga aaaactaaca agaatttttt aagaatgtct tagtaattat ttccctcatt 64980
gatttgactg acagcagcac tcgagctgca tgagctgcat aggcagtttt tgagtttcag 65040
tggaagcaag ggcacatcca acaatttgta caagagttca catggtcaca ttgttcttct 65100
tgaatttacc ttcgaaatat ttcatttaca atgtttcaga ggcttaaaac attgtgtatt 65160
ttcattcgca ctaatacagt tagttcagtg tgggtgagca gaaagctctt cctgatagca 65220
ttagtagatg ctagtgacct ctagtgctca aaagcagtac agatacaaat taaaaagaaa 65280
aaaaagacat gactttatga atagctacct gccaaggaca tctcagtgta gtgctggatt 65340
tacaagcaca actttagaaa gtttatgaat aacataccca gcatggcatc tactcttcca 65400
gaggaggtac aaaagactac agatgtgcgc atgcaaatct cagacgacgc cacacagagt 65460
cagtgtggca aaacagccga gaatgatctt atttatgggg atgaaatatg ggatgagtca 65520
tgaaagacca ttgaaaggat taccgtgccg ggtgaaaata atgtcttcaa accgacacct 65580
cgtattttac ctcaaagatg atgagcacat agactcctgc caggatcaat ccggcgataa 65640
gcacctgtgt ttccacggtt acatagagtg actggtgagt catggacaga ggaaccacct 65700
gactgtctaa cagaaaggcc tgcacactga tcagaatatg agcgctggag ggcaaaagaa 65760
agaaagatta gagagacgga gacacactag agcaggcacc atgacaggaa cataaatgtg 65820
cataacccac attataaaat gatcgcattt actgaactgt taacacaatt taaaaatctg 65880
atggcaatag tatgacaata ttattttact ttttttttaa atatagagca actgattttg 65940
tttggttggt cttacctgct aaccatttcg aatgtccttg ttctcagaat ttggtcactt 66000
cgttgggaat gcaatggtat agtccagtta taaagcacct gttcgaaaaa tactacagtt 66060
tgtattctga atgtataatc tctttaatct tttaatttta attaaatgta ttttacatac 66120
agcatcctaa aaagtatttg gatacttatt aggtcttata ttcatcctta aaatgaatgc 66180
atttgcatta tatacacatt aatataaaaa aaaggcattt tttttattat ataaataatt 66240
tacagtacaa tgccattcca aagtttgggg tcagtaagtt tattttttgt tgtttgcttg 66300
tttttttttt ttttttttaa gaacttatac tcaacaaaga atcctgacaa aatgtattac 66360
agcttctaca aacatatccg agtagcacaa ttgttttcag cataagagat gagatcattt 66420
ttttgtatat tcagaaattc tactaataag aaatgcttct tgatcacaaa atcggcatat 66480
tcaaataatt tctgaaggaa ttttagcttt gccatcactg caataaattg taacaatatt 66540
actgtttttc ctgtaatttt gatttgaatt tttttttttt tttacatttt aaaaaatctg 66600
actccgaact attttattaa agcataaata aacttatttt tgtgaggcca gattgacagt 66660
ctaattatat ttaacattag tttaatctgc tggtagtgtg aagaacataa ctcttcgatt 66720
tggctctgtt gaaacaactc taacctgctg agttcttctc cggcgagacc ccgcctcttc 66780
agtctgctcc acctggatca gaatatactc ctgggcttct tgtactgcct ccatcccccc 66840
caaaaacggc ccaccaacct gcagcttcag cagggagttg tcacgaaaat cagtaagatt 66900
catagctacc cgatcagttg ggttaagaaa aatgtccaaa aactaggaaa cacattacca 66960
atgaaaacac tataacacaa aatatccatc gagcttaaac atgagcattt tggaaaggtt 67020
ttgcaaactg atgtcagctg gccatggttt cattttggac agacaatccc ctcccaccag 67080
cagaaggtac tttgaagcac ttcagtgcat tgttcactct tcaaattcat ctctccagct 67140
ctgcaggacc cacagattgc ttcaagtatc aggcagatct gctgttatgc acgaagtcat 67200
aggcaagact gttaccatga cagaggccgc tgtaaatagc agatggtgag attgtcacag 67260
aaacggaaat gaattagcgc agcccttcag tgcaatctcc gaaccaaaca taaatccctg 67320
cagggtctga ggagttagcg cagtggcatg catcatcaca atatttgact tgtgcattaa 67380
tgattcttat ttatctagtc aatgcaaacc caaacaacgc agattcccaa acaatgcaga 67440
aacggggagg atacagaagc tctcaggtgg atgagactgc cagcatcctc caggggcttt 67500
ccctgtcagg atacatgctg aagaacagct gatgattcaa ataaatatag ttatttcaga 67560
gtgtcagaca agttctttga gcttttaagt gaaacaatca taaatgggtt ttattccata 67620
taaaaaaatc tgtggagtaa atttaatgag tagaaaacct actgaacaca gaacaacaat 67680
gatgaagatg gtgatgattt ttgttgtcct taagcagtgc ctataaaaac aaacgtaggc 67740
agatgttatc tcatccacct agcaacagaa atacaattat tgtcccagaa ttttcactat 67800
ttaatgtttc taaatttaaa ggtttggggt cagcataagt attgtgtatg tatttaagca 67860
ttaatatata gaagtgacct gtgttcacta ttatatatat atatatatat atatatatat 67920
atatatatat atatatatat atatatatat atatatatat tataaatata taattttttt 67980
ttctttgata gtgaagctac attttcatca gccactactc ttatctcaag tgtcacatga 68040
tccaggtttt ttttttattt tataacattt tcaacagaac agtgtttatt taaagtaaac 68100
tttagaaatg tctttaatgt cttggctcaa taataaaaaa ttaaaaaacg tactaacccc 68160
aaatgttgaa tggtagtgtg tgtatgccat acctgatggg aaatgacagt ttgaagtaat 68220
gttcacattt ctccatggat gtgatgtggg agagactggt cacctcgctg cccagcctgc 68280
acctcctctc caattcagca gagcttgcct cccatgattc ctctccagac cccaggcttg 68340
gctcatgcag tgtcatgtaa gttatactgc acaaaacagt gtaaaaacac tgggttacac 68400
actgtggtgc ttgcaaaaca ttgctctgtt tgtttgagca gtccaagaga ttgactctac 68460
caatggcgtg agtttggggc gggactttct gtttagtggt gaaatttaat tagcttgacc 68520
tggaaaacct gttaacaata atcattattt ttacagccac atctgttgcc gcaagtctca 68580
aggaataaac acttcacctt taaatttagt tgtgaaaatc caatccctct tggctaactt 68640
ttagtatcat ccaaagtaaa acatcacttc ttgcagctac tgaagcgatc agtcatctaa 68700
atgctaattg cagccacaca atagagatta aaactaatga aaggtgttaa aagcctgtta 68760
tgctacgcag ttctttgaca aattcatgct aagagaggat acacctaagt gcctagacat 68820
aacttgaggc ttttgtgttg attataggca gcaagacgca ttattctgac tgagagcaca 68880
atataatcgc tagcagcatt agcattcagc tcactgcctt acagagggaa tgaaaaatgt 68940
attactgagg gcagcagata gcaaccagcc attttagtcc tgtgacaaca gtttactcca 69000
tgtaggaccc ttgatctcag agggctgtct ttcagggtct tcaatagagc gtccacggtg 69060
gtactgcatg gtgggcccac caattgtttt gaattaaact aattggtgaa gaactgacaa 69120
acaaaaaact attttaattt aacttcaaat acatctagaa gctaaaattt agcagatttt 69180
attattaaaa ggtaatgtca tgcaaatgac tatgtcataa ctgaatatgc atatcagttt 69240
gacaaagtat gtcaaaacat caatatggtc tctcatgttg taaattaaag tgtatattat 69300
agaatttcat ttaatttgaa cattttaatt tgctcacaat ttctacacta taaagtattt 69360
tagagtttag cataacaaaa aaaaaaaaac atagacacat tttttataat ttacatggct 69420
ttttaagatc tagaaattat atttttaaaa ggaggcttct tcagatattg agtgggttga 69480
atcaaaataa taaatatctt aatgtttgtt gtttaaaatg attttgatat gttttgtcta 69540
cattttagtc attttaagcc acaccccacc cccagaagtt tgctgaagtc ccctagcggg 69600
ccctggccct caggttgaga aaccctgcaa tatggggtcc cttaaacaca caaacataaa 69660
aaaaaaaaaa aaaaaactaa tgtaatcctg tgtttgattc cattagaatt ttcattcagt 69720
ttgcaatttc cataagacaa cttgtcctac tttttatgag atttttcttg atgtacctca 69780
taaaataatg ttgcatgaaa atagtaatat tcagcattga ggaggacaca atatcctcca 69840
aacagaatta atacaggtgt gatccttatg actataactc ttcttgttac ataaaatcac 69900
tggctttaga gttctggtaa ggatacatgg gtgaatcaag gacgtattct ggagaaaaca 69960
ggaaattcat aaaacaaaat aactcatacc tcaaaaacat tgatgaacta cactattaca 70020
gttggtttcc acataaaatt attgatttgt atacaaaaat acaaacattt tgtatggaaa 70080
atgtggtatt cttgtgcaaa taacatggct agtgggaaca tattcttcac tggttgagca 70140
aactggaatg cgctccatgt ctagtattat attcaatatg ttggaatcat tcccaattat 70200
tatagacgct gacaactgaa agttcagctt ctgtactgca ggcagtgttt ggtttaatta 70260
agaagtacat ataggtcaag accacttcaa gatttctaaa tgccatacat tatgtgagga 70320
gctctgtttg ccttcaacct ggtaatatat aaagtaattg ttggaaatga aggtcacaaa 70380
gccacttttt ctcattactg aatgagaatg aggtcggtaa ttacagaccc caggtaatat 70440
tcctacaact gttctgccga agctttcttg actaaagcca agtcaacagg tcctgcaact 70500
ttggaagaaa ttagtggtta acgcttgcaa caacttgcaa acgaaaatta tattctatta 70560
tgcttaacag acaattaatt aaatagccag aaaactttga tttatatatt ttggtatata 70620
taattttacc tgctctgatt tgctcgcaga taataaggtt aaagcaggag caccattaga 70680
ttttattggt attggtaaat aaatacatat actgtaaata cataatacat acataaagta 70740
aataaatgaa tccagaaaaa caaaccttac cagaattgtt cactgcttaa cagaaaagga 70800
aacattgaat atgaaatatt gtgaaaccaa cagggaaata aatataggct cacctgtcat 70860
tttgggggaa cttgagaagg ggtgaccgtt ctgtgtggtt ggcttggttg gatttgtctt 70920
tgaggaggtt taccatgctg aagctgtgcc tgggaacaag gagagaactt attaaatccg 70980
agcatgatgt ctgtcataaa tagcatctca gccacattta gaaatcaatt cttggcatcc 71040
atttttaatg actcgtctat aaaaactggc agctgaaata aaatggaact aaaagttttt 71100
gagcagaact gaaagtcatt cctccttttt ggactctgtt aagtcatctt tacaccacta 71160
agaaacatcc ttgtcttgtg tgtcaaacaa ggtctaagct acatgatcat aaaataaatg 71220
tagattttca aacatccaaa aggttaacga caattatata agtcatcctt ctggtccact 71280
atgtccttct acagctgtct tgatcattta actgacacct cgtaatttgt cagggtggat 71340
gggcagattt acagagacat gaaagtgata tggttattac aggtttaagg acaacagtat 71400
cctgcttatt cgggccttga atactagggt ataaggttct ggccttggtt tcgatgctat 71460
aaaatacagt gacacattga aataaatcaa acagttgctt tgtgatttta ttttatgtca 71520
gtgaaaggct catgtattgc acgaatcccc aacaaaagtc aatgccgcaa tctcatgatt 71580
ttaaaatatg tatctttcaa catgtcatat aacagatatc caagtttaga acatcataca 71640
aagaaataga aggactatga tgtatgtaca tataaatctg aaatcctgac atgggaaatc 71700
aattgttttt tgcagaatgt gccagattta tgtcttaata gtatcttggt ttagaagttg 71760
catttctcta gtgctccgga tctggagttt tcaacagggg ctccacggca gtgcagcagg 71820
gggtcaaact tttttgtgga atttttttct ccattaaaaa atgactaaaa caaaatggca 71880
actaaagcta aagaagctaa agtacatctt taattgttcc tcccaaaata aaatgtattc 71940
tataagacag ggattcccaa aggataggat gtaaaatatt tctttgaaat accacctgag 72000
aatttaagct attatttcaa taatttaaga acacatttgc atgtcttctg atgctggtta 72060
attgtcacat ggcatgcaaa taaacatata ttttgatggc caaaacatta tattaaaatt 72120
attttgtcat atattgcgac tgaaatttga actgctggca tttcatctca tatattaaat 72180
gtatatttat aaaatatatt gtgatttcgg tttcatttca actaattctg cggcacaatt 72240
gggttatttt aattttacat ttgatttact tcattattag cttttcatta actcatgaac 72300
cccatgcagt ttccttgtga agcccctggt gtgcatcaat tataattatt tcaatggttt 72360
tgtaatgtaa gcatcataaa aggtaagtaa atagattaat atgttactaa atgcttactg 72420
tagtatatca ttaaaacagt atatttcaat ttaattgaaa agggccacta gcattgtttc 72480
atgcagtaat catactttat cctctaaact tcctcagaca aggacagctt tatttactgt 72540
agtcataaag caaacatttc acatctcata tactcaataa caacaaaata aatcaataga 72600
agtctccaga agaagagaga gaagagaaag gatggattct gagctattgc tcagagacac 72660
cagcaggtgt tgagattttt cggcctgtgt aaatagaaca gatggaaatc cggagaactc 72720
tgtgggctaa ttactggaac ctcttcagta atctaattat tgtgaaaaat tctctgtttg 72780
tcataattaa tgacagttta aatgggtaaa gtccctcttc tattggctct gagtttgtgt 72840
gtaagttatg gagagccttt tgcagaatgc caaaatagat caatgctgct cagcacagga 72900
cagactatag agtcaaccct agtccaattc taacacatca ttgggcaaat cccaaacctc 72960
agctgcttag cattacagag gcctcaaaca actcacccac ccctactgat gcctgcgcac 73020
tgcaaacagc tgggatggtg tgtgtgcgtg tgtgagtgtg tgtgtctgtg ggctccagac 73080
aagacataat aggcatggcc tccagaatat atcctggtgt tgagtttggt caaaagggag 73140
attagacagg atatttcaag gcctttaatc cttctccctg cagttacaca acagagagga 73200
gatttgaaat gttagctcac cgaatgcagg atttataaat gaagcaaagc cttcacttat 73260
tgtgcctgaa tccaaatgtg tgaggtccag atgagaatga aaccaaagag gggggagtac 73320
gtaacccagt gggacaccta taacatcctt ttagatccgg cctcaaatac cagcctaatt 73380
gaagtctacc tgacatactt acattaattt cctgaacaat atgaagaaag ttgaaatttt 73440
tgactaattt actttactta aaatactttt attaagcaag gatgcattaa atgccaaaaa 73500
agggacagaa aaaaacaaat gtgtgcctat atgtgtgtct atataaacgt gtgtgtgtgt 73560
gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtcttt taaagtactt ttgataaata 73620
agtgcagtct cagactttca aacacataaa aaatttgact gaaaccacca ttttaaataa 73680
taatttatgt ggaatgatat atggcttact ctggcatatt tcccatagga caaaagataa 73740
acaaacaact attgaaatac atatatcttt ttaaataata catgtgatgt gatcagctga 73800
tgtcattgag agtggttatc attaaagaat tcctgcagga gagagcagtc atgagagcag 73860
aagaccacat ctcatgcatg actaacaatt aatcacgtga tggctgatct aaaactgcac 73920
tctctaatcc gaaaagtgtc acaaccacaa gcttgagatt aagaccccca ttgtcatagt 73980
ccacagtacc ataccacact caattttttt ctctcacaaa gacacacatt tgatcttact 74040
acagtaatgc aactccacac gtgagcacaa atcctcttta gagttgatta gcagctgttt 74100
cacacagaaa agctctcact aagggttctg gggaccttct ctggcaaatg tgttctgctt 74160
aatgtcagcc ataacagtgg aagcacaatg gaagcacatt ttgcttgaag attttctagc 74220
atgaggtttc tttgaaacat ctcaaaggtt aagcatgtta ctttgttaaa atactttctc 74280
ttaccacagt ttattgtgca gagacaaata taatcaagtc attaatagac tgatctccca 74340
gaatagtgta aacactgtgg cactatcaaa actattgttc tgtttgtttg tgctcaaaag 74400
tctggttgaa tgtgtttggg ctggacaacc tgtttgtcca aatcatcttt ggcatatgat 74460
gcattcaagt cctccaggaa aaaaaattct taaaaaaaaa tacttacaat tcggggagcc 74520
acgattatga tgttaggttt gttcaagcca cattggttgg acaaaggtgg cgacattccc 74580
agggttatta actaaaacta aactaaaacc attaaaaaat tctttacttg aaataaaata 74640
atttctcaaa aattcatttc agacaatatt tctttttttt tttatttagt ttgatgtact 74700
aaaacaaaaa atgtataaaa cttccaaaat ctaaaattac tataaaaaca aacaaacaca 74760
cacacacaca caaacaacta aaactacaat taaaacggga gacgcttcga aatattaatg 74820
tcaatgataa taaattaaca ccagaggtac ctttctataa aaacaaacaa acaaataaat 74880
aaatattttt ttaactacta gaaaatttca aacaaagaat gctgttatgg cttgcaaata 74940
ttaaattgta aaatatagta tttatatatt atttatcata attttatcct atttttcatg 75000
taacttgtag ttagatgcta gctactgtaa aataataatg aaaataataa tttaattaat 75060
aaaaaatttg acttaataca gctgctgcaa ctcaaagttg taagttttcc acttgtaatt 75120
ccgactttta attattaacg agaatgcaca agtaaactaa tcaaactaat aaataattag 75180
tattaattat taattgtaat ataaataaat aataatatga aaatataaag ttaaaatact 75240
aacttaaaag gatgtatata ttttttattt tatttaattt tagggtgaaa tatcccttta 75300
acagaattga tctttgatga actatttgac tgtcctacct atcatcttga tggacgtcag 75360
tgtagattat gcagtttccc gagggcatgg ctgcagcctg cagcgatttc tgtgtctcta 75420
tcttccctga gaatccctcc agcagacgaa gctcatcaaa gttcccagcc acagtgtcag 75480
acttcctgca gcctaccctg ctggagtgac cctggcctcc ggtttgagac atctccacct 75540
caatattact cttattctcc aggtacat 75568
<210> 2
<211> 843
<212> PRT
<213> Carassius auratus
<400> 2
Met Tyr Leu Glu Asn Lys Ser Asn Ile Glu Val Glu Ile Ser Gln Thr
1 5 10 15
Gly Gly Gln Gly His Ser Ser Arg Val Gly Arg Arg Asn Ser Asp Ser
20 25 30
Val Ala Gly Asn Phe Asp Glu Leu Arg Leu Leu Glu Gly Phe Ser Gly
35 40 45
Lys Arg Glu Thr Gln Lys Leu Gln Gln Ala Ala Ala Met Pro Ser Gly
50 55 60
His Cys Ile Ile Tyr Thr Asp Val Gln Gln Asp Asp Arg His Ser Phe
65 70 75 80
Ser Val Val Asn Phe Leu Lys Gly Lys Ser Asn Gln Ala Asn His Glu
85 90 95
Gln Ser Pro Leu Leu Lys Phe Pro Gln Asn Asp Ser Met Thr Tyr Met
100 105 110
Thr Leu His Glu Pro Ser Leu Gly Ser Gly Glu Glu Ser Trp Glu Ala
115 120 125
Ser Ser Ala Glu Leu Glu Arg Arg Cys Arg Leu Gly Ser Glu Val Ala
130 135 140
Ser Leu Ser His Ile Thr Ser Met Glu Lys Cys Glu His Tyr Phe Lys
145 150 155 160
Ile Ser Ser Pro Ile Arg Cys Cys Leu Arg Thr Ala Lys Ile Ile Thr
165 170 175
Ile Phe Ile Ile Val Val Leu Cys Ser Leu Phe Phe Ser Met Tyr Pro
180 185 190
Asp Arg Glu Ser Pro Trp Arg Met Leu Ala Val Ser Ser Thr Glu Ser
195 200 205
Phe Ser Met Asn Leu Ser Asp Phe Arg Asp Asn Ser Leu Leu Lys Leu
210 215 220
Gln Val Gly Gly Pro Phe Leu Gly Gly Met Glu Ala Val Gln Glu Ala
225 230 235 240
Gln Glu Tyr Ile Leu Ile Gln Val Glu Gln Thr Glu Glu Ala Gly Ser
245 250 255
Arg Arg Arg Arg Thr Gln Gln Val Leu Tyr Asn Trp Thr Ile Pro Leu
260 265 270
His Ser Gln Arg Ser Asp Gln Ile Leu Arg Thr Arg Thr Phe Glu Met
275 280 285
Val Ser Ser Ala Pro Val Leu Ile Ser Val Gln Ala Phe Leu Leu Asp
290 295 300
Ser Gln Val Val Pro Leu Ser Met Thr His Gln Ser Leu Tyr Val Thr
305 310 315 320
Val Glu Thr Gln Val Leu Met Ala Gly Leu Ile Leu Ala Gly Val Tyr
325 330 335
Val Leu Ile Ile Phe Glu Ile Val His Arg Thr Leu Ala Ala Met Leu
340 345 350
Gly Ser Leu Ala Ser Leu Ala Ala Leu Ala Phe Ile Gly Asp Arg Pro
355 360 365
Ser Leu Met Thr Val Val Glu Trp Ile Asp Tyr Glu Thr Leu Ala Leu
370 375 380
Leu Phe Gly Met Met Ile Leu Val Ala Ile Phe Ser Glu Thr Gly Phe
385 390 395 400
Phe Asp Tyr Cys Ala Val Lys Ala Tyr Gln Leu Ser Arg Gly Arg Val
405 410 415
Trp Pro Met Ile Met Ile Leu Cys Leu Ile Ala Ala Val Leu Ser Ala
420 425 430
Phe Leu Asp Asn Val Thr Thr Met Met Leu Phe Thr Pro Val Thr Ile
435 440 445
Arg Leu Cys Glu Val Leu Asn Leu Asp Pro Arg His Val Leu Ile Ala
450 455 460
Glu Val Ile Phe Thr Asn Ile Gly Gly Ala Ala Thr Ala Val Gly Asp
465 470 475 480
Pro Pro Asn Val Ile Ile Val Ser Asn Gln Asp Leu Arg Lys Lys Gly
485 490 495
Ile Asp Phe Ala Ala Phe Thr Gly Tyr Met Phe Leu Gly Val Cys Leu
500 505 510
Val Leu Leu Thr Ser Phe Pro Phe Leu Arg Met Leu Tyr Trp Asn Lys
515 520 525
Lys Leu Tyr Asn Lys Glu Ser Ser Glu Ile Val Glu Leu Lys His Glu
530 535 540
Ile Leu Val Trp Arg Gln Thr Ala His Arg Ile Asn Pro Ala Ser Arg
545 550 555 560
Glu Glu Ser Ala Val Lys Cys Leu Leu Met Gln Lys Val Leu Asn Leu
565 570 575
Glu Ser Leu Leu His Lys Lys Leu Lys Thr Phe Gln Arg Gln Ile Ser
580 585 590
Gln Glu Asp Lys Asn Trp Glu His Asn Ile Gln Glu Leu Gln Lys Lys
595 600 605
His Arg Ile Thr Asp Lys Ile Leu Leu Val Lys Cys Leu Thr Val Leu
610 615 620
Gly Val Val Ile Phe Met Phe Phe Leu Asn Ser Phe Val Pro Ala Ile
625 630 635 640
His Leu Asp Leu Gly Trp Ile Ala Ile Leu Gly Ala Leu Trp Leu Leu
645 650 655
Val Leu Ala Asp Ile Gln Asp Phe Glu Ile Ile Leu His Arg Val Glu
660 665 670
Trp Ala Thr Leu Leu Phe Phe Ala Ala Leu Phe Val Leu Met Glu Ala
675 680 685
Leu Ala Gln Leu Gln Leu Ile Asp Tyr Ile Gly Glu Gln Thr Ala Val
690 695 700
Phe Gly Cys Asp Thr Phe Tyr Cys Tyr Leu Leu Ser Gln Ala Val Pro
705 710 715 720
Glu Asp Glu Arg Leu Ala Ile Ala Ile Ile Leu Val Met Trp Val Ser
725 730 735
Ala Leu Ala Ser Ser Leu Ile Asp Asn Ile Pro Phe Thr Ala Ala Met
740 745 750
Ile Pro Val Leu Ile Asn Leu Ser Gln Asp Pro Asp Val Asn Leu Pro
755 760 765
Ile Lys Pro Leu Ile Phe Ala Leu Ala Met Gly Ala Cys Leu Gly Gly
770 775 780
Asn Gly Thr Leu Ile Gly Ala Ser Ala Asn Val Val Cys Ala Gly Ile
785 790 795 800
Ala Glu Gln His Gly Tyr Gly Phe Ser Phe Met Glu Phe Phe Arg Leu
805 810 815
Gly Phe Pro Met Met Leu Met Thr Cys Thr Ile Ala Met Cys Tyr Leu
820 825 830
Leu Ala Thr His Ile Gly Leu His Trp Asn Thr
835 840
<210> 3
<211> 67316
<212> DNA
<213> Carassius auratus
<400> 3
atgtacctgg agaataagag taatattgag gtggagatat ctcaaactgg aggacagggt 60
cactccagca gggtaggccg cagaaattct gacagtgtgg ctgggaactt tgatgagctt 120
cgtctgctgg agggattctc tgggaaaaga gagacgcaga aattgcagca ggccgcagcc 180
atgccctctg gacactgcat aatctacact gacgtccagc aagatgatag gtaggaggac 240
agtagttcaa atacttaatc atgaataaat actgttaaac gggtatttcg ctccaaaatt 300
aaaatggaaa atcatcatat actcatccat ctaattttgt tgcaaacttg aattactgac 360
attcttctag ggaacacaaa ataagtattt ttaggaatgt ttttgtccag tgaaaatcag 420
tggagtgagt ccaaagcaac attcagaccc cattttcatt atatggacca aaaaataaat 480
aaaataaaaa gacatttttc atataacaac aggataatat ccgtttaagg taatttttag 540
ttttatattt attatatgta attaataatt agttattagt tcactggtgc attcaagtta 600
acaattacac gtcataatta caagtgggag acttgcagaa tctgtattga tgtacttttt 660
tttttttttt ttttttttac aaattattat taatattttt atatttaaag taaatcatac 720
ttgcatgaaa aatatggtag tattgcacaa ttatgataat gaacatatta tataaatata 780
tgtaacaatt taatttgtag cttcttcata atttaaataa acataagcta aaacacaccc 840
gctttcttta tttgtcattt tgtagttagt taaaaaaaat tgaattaact ttgataattt 900
ttcattttat ttacttattt atttgagtac atcaagttaa actaaaatga gaaatatttt 960
ctgaaataaa attgtgttaa aggaattata ggcataatta caacttctca aattgtagaa 1020
atgaactttc ctggaggact tgaatgcacc tatatgtcaa agatgaattg gatcaatggg 1080
tagtcccacc ccaaacacac tcaagacttt caagcttgat agtgccacag tttttagact 1140
tttctgggag atcagtctaa aaatgacttt cttatagttg tccctgcaca ttaaactttg 1200
gtaagagaaa gtattttaac aaagtaacca cctctctttc aagatgtttc aaagaaaggt 1260
catgcttgga aaggaatctt aatgcaaaat gtactttacg aattcattgt aacagtgaac 1320
atctactatt atggctgaca ttcagctgaa cacatttggc agataaggtc ttcagaaccc 1380
ttagtgagag cttttctgtg tgaaacagct gcttatcgac cttaaagagg attggtgctc 1440
atgtgtggag tcacattact gtagtaacat catgaaaaat gtgtgtctat gtggcggggt 1500
gtgtgtgtga tggtaccata gaatatgacg acgggggtct taatctcaag ctcgtggttg 1560
ttgcactttc agatcagaca ttacattttg gatcagccat cacgtgatta attggtagtc 1620
atgcatgaga tgagatctgc ttctgctctc ataactgctc tctcttacag gaattcttta 1680
acgataacca ctttctcaat gaaatcagct gatcacatca catgtattag ttaaaaaaca 1740
tatatatttc agtagttgta tctccattct ctctatcttt ttctgtctta tatattctat 1800
aatttaatta tataaaacgt tcaatagttg tttgtttatc tttctgtcct atgggaaata 1860
tgccacagtt atataaaaat atgccatata ttatcgcaca catattattg tgtaaaactt 1920
tggtgttagt aagatttttt aatgggtttg aaagtttctt atgcttacca agactgcact 1980
tatttaatta aaagtacttt aaaaacaaag caaaaaaaaa aaaaaaaaaa aaaaaaaacc 2040
cagatataaa tgtataatgt gtgtatacac atttgtaaca ctgtaaatgt ttttactgtt 2100
acttttgagc tatttaatgc atccttgccg taaaaaatta ttctgtttga cattatagta 2160
tgatgtgatt aaaaatggag cagaatttct tcatattgtt aatggaatta aattatgtca 2220
ggtagcattc aatttgactt gtattctatg ccagatctga gaggatgata ggtgtcccac 2280
tgggttatgt actccccttc tttggtttca gtctcatctg gaccacacac actcagattc 2340
atgcacaata agagaaagct ttgcttaatt tataaatcct gcattctgtg agctaacatt 2400
tcaaatctcc tctccgttgt gtaactgcag ggagagggat taaaggcctt gaaatatcct 2460
gtctaatctc ccttttgccc gaaacctaac accaggatat atcctggagg ccatggctat 2520
tatgtcttgt ctggagtgct caaaaacaca cacacacaca accacaccca cccaccccag 2580
ttgtttgcag tgagctgagg cattggtagg ggtgggagag ttgtttgagt cctctgtaac 2640
actaagcagc tgaggtttgg gatttaccca aagatgagtg ttagaaatgg actagggttg 2700
actctatagt ctggccggcc tgtgatgagc agctttgatc tattctggca ttctgcaaaa 2760
ggctctccat aactcacaca caaactcgga gccaattgaa gagataagag ggactttacc 2820
catttaaact gtcattaatt atgacagaga atttttctca tttattagat tagtgaaaag 2880
gctccagtaa ttagcccaca gagttctcgc gatttccatc tgttctcttc acacaagccg 2940
ataaaaaaaa tcaacactgc tggtgtctcc gagcattaga gaatcttttc tcttctcccc 3000
tttttttttc ttgagacttc tattgatttt tctgttgtta ttgagtacag tatatgatat 3060
gagaaatgat tggctatagt aaataaagct gtccttgtct gaggaagttg agaggataaa 3120
gtgtgattac tgaacgaagg aatgctaatg gcccaaatta tattgaaata cgttaatgtg 3180
gttttacagt tgaaatacat tagtggtact acaaaattat tacaattatg aatagatata 3240
atttttgcat gccagggttg cccaaactgg ggtttgcaaa gaaactgcac agggttcagg 3300
gatcaggagt taatgaaaag ataataatga aatgaatcaa atgtaatatt aaaataataa 3360
tactaaagaa aacaaacaca gatatctggg agaactggct gttgtcagac tcattgtgca 3420
tacagaaatc tgatgggatt attacaatta atggcaaaag gaatttttga aaatgtaaat 3480
tgatatttcc tataggataa ggacatgcta cagcaaaaga ttgtgatgcc tttttttttt 3540
gggaaaatat tagttgcttg cacattccac tatccttggg gtcagaattt aaattttata 3600
tgtacattgt agttctgatt tcttttaata atactcttaa gttggatatt ggttaaatgc 3660
attacataag catttcactg acacaagaca aagtaacaaa gcaatagttt atttcacaat 3720
agaccagaag gatggctttt atgattgtta ttaattcttt tggatgtgta gcttgcttat 3780
gtttgcaaat gtacatttat tttatgatca tgtagcttag accttgtttg acacactaga 3840
ccaggatgtt taataaagat gactaaacga agaccaaaaa ggaagaatga ctatcagttc 3900
tgctcaaaga cttttagttc cattttattt cagctgccag tttttataga agagtcattc 3960
aaaatgcatg ccaagaactg attttctaaa tgtggctgag atgttattta tgacagacat 4020
catgttctga tttaatatgt ttctatgtgc cttgttccca ggcacagctt cagcgtggta 4080
aatttcctca aaggcaaatc caaccaagcc aaccacgaca gaacaatcac cccttcttaa 4140
gttcccccaa aatgacaggt gagcctaaat atatgtcccc attggtttca cagtatttca 4200
aatttgatgt tcatttgttc ttgtttactt ttctgatctc ttcaattaac tatttgggta 4260
aggtttgttt atttgacacc agaatgtatg tatttatttg acttgtatat atgtatttat 4320
aaatatcaat aaaatccact ggcactccta ctaatgatct ttttaaatca gtttaatggc 4380
aattctggct attactatta ctatactatt ttcgtttgca aagcgttaac cactcgtaca 4440
caaggaaatg tatccctctt tctttctttc aaagttgcag gacctgttga ctcaataaag 4500
attctgaagg aatattacct ggggtcttta attaccgacc tcattttcat tcagtaatga 4560
gaaaaagtgg ctttgtgacc ttcatttcca actatttata tatatatata ttttatatat 4620
taccaggttg agggcaaaca cagttcctca cataatgcat ggcattctga tatcttgaag 4680
tggtcttgac ctctatgtac ttcttaatta aaccaaacac tgcctgcagt acagtatctg 4740
aactctcagt tgtcagcctc tatattaatc gttattgatt ccaacacatt gattataata 4800
ccagactgga gcacattcca attcgctcaa cctgtcagga atgttatgat tagtcatgtt 4860
atttgcataa cagtctccaa atgtctatat aaaacgtttt gtatttttga actatctgta 4920
atagttttta gttcttcaat attttagcat ttcctgattt ccccagcatg agtccttgat 4980
tcacccatgt atccctacca ggactctaaa gccagagatt tttatgtaac aagaaaactc 5040
atagtcataa ggattacacc tgtgtttcat ttagtttggg ttatataatg tcctcttcag 5100
tgctgaatat tcctattttc atgaaacatt attttatcag gtatgtcaag aacaatctca 5160
taaaaagtag gatacgtttt cttaagaaaa ttgaaagctc aatgaaaatt caaatggaat 5220
caaacacagg attttaatgt cttaaatctt tgactgtgta agaaacccct tattacagtg 5280
tttcttatta cagtgtttct tgtttgcagt cttttttttt tgtagttatg tcaaactcta 5340
aaaatatgaa aatagaaaaa tgaataaaaa aatacatttg tgcgagcaaa catttaatta 5400
aatgctaaat tacgcccttt gtcatgattg caattgcatg gagtatatta tatagagtca 5460
agacattact attattatta atgacactgc tgaaatttag cttctagatg tagttgaagt 5520
aactttacat tttgtttatc agtttttaac ctgataactg tcactgacgt ttttgaagat 5580
agacttgaat gtgcatgata caaaccaaaa tttttatatt tcatgactga aaacattttg 5640
taacatgatt ttgatgtgcc atttacatgg taatgcaatg tctgatttta aaatgggttt 5700
tgaaggatga attttgagat tttatgtttt caagtgatat ataacttctg atgatttcta 5760
aaatgtgata gagaaaaagg caacgaggaa gtcttttttt taaacaaagg tcaaagctcc 5820
ttttgtaatg tagatttctg agggtgcact cttgtcataa attgatatat tacttttcct 5880
acataatttt taacaacaaa tattggtata atatatattt gggagtctta gacctttcca 5940
acgatatata gtttgtcaag attagattaa atttgattgt aatatagtat agtcaacgta 6000
ggtgtcccgt atacgggacg gggtgacatt taacaggtta acagattatt ttgatatcaa 6060
acaattgatg ggccctctgc agtaccacgg tggacccttt gttgaagacc cccagtctgt 6120
gttatcataa tggccctctg agatcaagag gcatacaaag agtaaagtgt tgtcataatg 6180
ctaatatggc tggttgctat ctgttgccct cagtaataca tttttcattc cctctgtaag 6240
gcagtgagct gaatgctaat gctgctagcg attatattgt gttctcagtc ggaataatgt 6300
atctctgctg cctataatca acacaaaagc ctctagttat gtctgggcac ttaggtgtat 6360
ccactcttgg tagcatgaat ttgtcaaaga actgtgtacc ataataggct tttaacacct 6420
ttcattgttt ttaatctttg ttgtgtggct gcaattaaca tttagatgac ggatcgcttc 6480
ctagctgcag gagtggtgtg ttactttgaa tgataggatt ggattttcac tactaaattt 6540
aaacctggag tgtttcattt gcataagact agcggcaaca catgcaaatg caaaaataat 6600
gattattgta cacaagtttc ccgggttaaa ctaattagtt ttaccactaa acagatagtc 6660
ccgctccaaa ctcatgccat tggttgagtc agaagtcaat atcttggact gctcaaacaa 6720
acagagtaac actttgcaag catcacagtg tttaacacac agtttttctg ctgttctgtg 6780
cagtatgacc tacatgacac tgcatgagcc cagcctggga tctggagagg aatcatggga 6840
ggccagctct gctgaattgg agaggaggtg caggctgggc agtgaggtgg ccagtctctc 6900
ccacatcaca tccatggaga aatgtgaaca ttacttcaaa atatcatccc ccatcaggta 6960
cggcatacat acactcaaaa tgttgggtta gttatataga tagatatcca tccatccatc 7020
catgcatcca tccatccacc catccatcca tccatccatc catccatgca tccatctatc 7080
cacccatcca ccctacaccc atccatgcat ccatccatcc acccatccat ccatccatcc 7140
atccatccat ccatccatcc atccatccat ccatgcatcc atctatccac ccatccatcc 7200
tacacccatc catgcatcca tccatccatc catccatgca tccatctatc cacccatcca 7260
ccctacatcc atccatgcat ctatctatcc acccatccac cctacaccca tccatccatc 7320
catccatcca tccatccatc gtgtgcagga gagccattaa atgattgtag aaatcccttt 7380
actctagctc cataactcaa aattctggga cattaaatgt gtttttgttg ctaggtagat 7440
gacataacta aacatgaacc taaatttgct tttaaatagg tgttgcttaa ggacagcaaa 7500
aatcatcacc atcttcatca ttgttgttct ctgttcagta agtttttcgg tcgtcaaacc 7560
tactcaacag cttttgttat atagaatagt atccaattat gattgtatta caaacgctca 7620
atgattttat ttgtctgacg ccctgagata actatattta tttgaatcct cagctgtttt 7680
tcagcatgta tcctgacagg gaaagcccct ggaggatgct agcagtctca tccaccgaaa 7740
gcttctgtat ccttcccatt tgtgtacttt agagaatctg cattgtttgg atttgcactg 7800
actagataaa taagaatcat taattcacaa gtcaaatatt gtgatgatgc atgccactgc 7860
gttaactcct cagaccctgc ggggattttt tggttggttc ggagattgca ctgaagggct 7920
gcgctaattc atttcccttt ctgtgacaat ctcaccatct gctatttaca gcggcctgtg 7980
tcatggtaac agtcttgcct atgacttcgt gcataacaac agatctggct gatacttcca 8040
gcaatctgtg agtcctgcgg agctggagag atgaatgtga agagtgaaca atgcactgaa 8100
gtgcttcaga gtaccttctg ctggtgggag gggatcgtct ggccaaaatg aaaccatgac 8160
cagctgacat ctgtttgcaa aaattgttca aatcactcag gttaaagctt gatggatatt 8220
tagtgtcagt attttaattt gtttccctaa ctcatggtag tttttcttaa cctaactgat 8280
ccctgtagcc atgaatctta gtgattttcg tgacaactcc ctgctgaagc tgcaggttgg 8340
tgggccattt ttgggaggga tggaggcagt acaagaggcc caggagtata ttctgatcca 8400
ggtggagcag actgaagaag cggggtctcg ccggagacga actcaacagg ttggagatgt 8460
ttcaatatat ctattgcttt ataattcatt ttgttgaaac atttagcttg aaaagtgtgt 8520
ttattcttta ataaaaatag tttggggtca gaaagggttt ttaatgtttt gaaaagtcac 8580
ttttgcttgc caagactgca ttgatttgga tcaaaatgac agtaaaaaca gtttattctt 8640
gtgatggcat agctgaattt tcagcagcca tttatcaaat cttcagatcc ttcagaaatc 8700
atttcaatat gctgatttgg tgctcaagaa acatttctta ttattatcaa ttcttataat 8760
gttctctcat ttcttatgtt gaaaacagtt gtgcttctta atacttttga agaagtcgta 8820
atacattttt ttcttaagaa ttatttgata agtagtaagt acatgttaaa aaatctttct 8880
gaccacacac ttttgattgg tacagcattc tatagaatag aatagaaata aaaatatgta 8940
tttaaatgcc ttatagtttg attgtaaact aaaggcattt atacatttta aggagtcact 9000
tataagtatc caaacacctt ttcaggatgc tgtatgtaaa atgtatataa aatgaaaatg 9060
aaaagattaa aaaagtttat tctaaacatt cagaatataa attctaatgt ttttctaaca 9120
ggtgctttat aactggacta taccattgca ttcccaacga agtgaccaaa ttctgagaac 9180
aaggacattc gaaatggtta gcaggtatga ttgcccattc ctcatcaaac aaagacattt 9240
caggttatat ggtgcacttt attgtatcta ttttgctgca ttaaaaaagg agattaatca 9300
cactactgtc atcagatgtg aactttgcta atttgccagt agttcagtca atctgatcat 9360
gtgatgatgt tatttttgca gtagctcctg tcctcgtata tgctttatgt gtctccatct 9420
ctttgtcttg tcctccagcg ctcctgttct gatcagtgtg caggcctttc tgttagacag 9480
tcaggtggtt cctctgtcca tgactcacca gtccctctat gtaaccgtgg aaacccaggt 9540
gcttatggct ggactgatcc tggcaggagt ctatgtgctc atcatctttg aggtaaaata 9600
tgaggtggcg gtgtgaagac attattttca caccgcacga taatccactc aatggtcttt 9660
ccatattcca tccccataaa caagatcatc ttggctgttt tgccacattg aatgtgtgga 9720
gtcgccagag atttgtgtgc gcccatctgt agtctttcag gaggagtaga tggcgtgctg 9780
gttatgttgt tcataaacat tctgtagatc cagaactatg ctgagatgtc cttggcaggt 9840
agctgttcgt aaacttacag tttgtttttt tatttttacc tgtacctgct gttgagcact 9900
agaggtcact gggctctacc aatgtaaatc acaagaaata tatccgattt ttggaatacc 9960
agaaagtgac tttaaattgg attacttgaa ttggattgca aaattgcttg aattttatag 10020
caagaccaaa ctgtattagt gcaaacgttt gaaagcagtt tttatttttt tattttaaat 10080
tggaaataca ggctttaagc ctttaaaaca ttccaaatga aatattatga agtcaagtca 10140
agaagaaggc tcctgtacaa aatgtcagat gtcccttgct tcgtctgaag cacaaaaaat 10200
tcccacttca attcatgctg gataacatgg atcattcaga gttcgtgcag ctttagtgct 10260
gctgtcaatc aaatgaacat gagccagact aagacattct gaaatagaag ttattttaca 10320
attaaaatgt tcactcaaat gttatgatat catttggtat aaaattgtaa attataaaga 10380
atgcaaaata agaccattgt cactagtggt ctcctttgga ccacttgtaa aaatttactt 10440
ttctggtttc tattgctcat gatgccagtt caccctaaaa atgaatcatt tctgatttta 10500
tatatttaca tgttttaatt ttttgcttta ttttgcttta tttttgctca ctgtaactct 10560
tgaatcatgt agattattac agagccttac cgcaaaacac tcctccacat ttttaacttc 10620
atcttctccc tgtagtgcac actttttaga gtctgtggct ccagggggac acgagggcag 10680
aggggacctc ccttcctaat tacatttatt tcttcaggag ggacagcatg ctgcgtgtcg 10740
aagagtttaa ttagaccttt gtgagaatgc taatggagac tttgggggcc tgtgtttcca 10800
cttttaccgt taaaactaat gcttcataac tatggctaca ccatcatcaa agagctgaga 10860
aagtaaaaat tatatgtttt taaaagtgaa ctaatgaaca gattttatgt tgattgggtg 10920
agtcatcgta attttattta ttgtgttttt aaaacagggt tacttgcgga acataacctc 10980
tgtgatcatc ttcttatgag aaatttatat tatattatat tatattatat tatattatat 11040
tatattatat tatattatat tatattatat tatattatat tatattattc tgaccatttg 11100
aaaccattac aacttcagtc aactgtgata tgtatatgaa ctagttccca ggtgttttag 11160
aaatcatcaa aaagtgttag aaaaacacag tagctttgct gtccaaccga gtccagtctg 11220
ttaattttta gtgatgaatt tcacgtacat aacacggcat gacatttcag taaaagtaac 11280
ataacacata aacaacactt gctcatacag tcttagtcta aatgtgtctc tatgttcagt 11340
tattctataa ctttttttat cttgactttt aaaacttggg aatatagcca ccattaccca 11400
gcccagtgat gattaaaaat atagctgctt ctcaggcatt gatctaaatg gctaatgatg 11460
ttgccaaatg tatgtgtgca tgccagaagg aagttgcagc tgcccagatt gtgcctttca 11520
taatcagctt ttaattgact gctgagtcag atgatatgct acagtactgg acatttaaag 11580
ttttttttta ttcgctttgg tactattttt acaagcaact gttacatttt cacttttttc 11640
agtcagttgg gatttttttt aattatacac cttacttgtg aaaatagtac agtatagcat 11700
aataaatgag cagcatagca atcgtagtgg aaaaatgtaa acattttaaa aaaattctct 11760
atggcatttg gttaatcccc cttttgcttt aatgacagac agcaccactt gagttttgaa 11820
tacaacctta aagatcatgc tattgagcat aatttgatat cttcaaaaga gtattgctat 11880
ccattgtaaa caataatatc tgtcatcaat acccccaccc cccttttttt gggctgcttt 11940
gattagtgac caagaattgt gcagaatcct aaatatttca tacttaacat ttctttcata 12000
cataacatta tttctacata ataacatctt tcaatatgat aaaacttaaa atagatttga 12060
ttaacattac agattccaca gtctgtggtc tcaaactttt ggactccatt gtaaacaggg 12120
aatcctttgt tgtattgacc tgtgcctgat cttctgatct ccctctctgc attgcacagc 12180
agcttggtga taatcctctg agctgatcta gaatcagcac tctgaaaaca actttgatta 12240
aaagggctca gatggtgagt ttcatcagca gctctgatag ctaaatctca tttgcctcga 12300
gagagagaga gagagagaga gagagagagg gcaaaacctg aaatcggaga tatataatag 12360
tatgagatgg ttataaatat taatatgcct taaaagattc atgaataatg tattttctca 12420
atctaatcgc agatatctcg taaacacttt aataatggct gatagattat tcttcaatta 12480
gactagagtt acagtttctc attaactggg gggctttgag tataaaacta acatcacatc 12540
tcacacaggc acattctgac atttcattta gccatgaact ctttcttact gtataagtga 12600
gagtaattgg tttaaatcgc aaaacagaga cacattagtc tcagaggata ctttcatatg 12660
caaagcaact caatgcatat ccatgttgct gattaattct gcacagaaag cagtgttcaa 12720
caatttatct taatgacctg ttttagactt acaatcacaa cattgcacca agtgttcctc 12780
cccctcaggg aagtttccgg actgacatag attacttgct ccttccagac tggagtctct 12840
tactgttatc ctgcatgttg tgtactcatc gcccttcttt tgctcttcta gctgattaca 12900
ctgtcttgta atgactgctc ccaccttgac acatgacacc aaaagaggtg catcagacac 12960
tttttgattc aggtgtttca gtcaagtgct ctcaccagga aaacagatgc tgaagatgtt 13020
gatatctgac agtgcacttt aaggcagcgc ttttagtcca gagggtgaat gaagagcaga 13080
aaaccagtag atgttgtcga ctgacacata tattcttgtg aatctggaat taccatttga 13140
ttaaaatagt gcataaaagg gtcagaatga attaaatgta agaaatgagg ttgatcgacc 13200
ataaatgaag agtggggaag agggttaatt atcatttttg atgagcaaat gtattcactt 13260
gtccaaaggc tattttacag ccttatgttt tacataatta atagtgttta ctaagactag 13320
aatcgctgtt accgttgctg ataggaataa ttttgtgcta cagggtgaga atgatacctc 13380
ttattatgca gcttgttgaa attagttgta ctattacttt tctaagcaat cagacgtttg 13440
gtttttgcct ggctaagcaa tgccctgcat tgtgcatagg gaagcacaaa tctagtttgt 13500
ggtacattat tataagccca gatttgtaat aaaattgtca aaacaaattg tactctaatt 13560
atgatatatt accgctatct tatttttctg cgtttatttg ttgttgcaga ttgttcaccg 13620
tactctggct gcaatgttag gatccctggc ttctctggca gcgctggctt tcattggaga 13680
tgtaagtttt tgttttagag aatgttattt tactccattt ttatgtatat tgcttacact 13740
ttgtcaagag ttggactctg ggacttcatt cattttgaaa attgcagtga tgatcttatt 13800
gttactagct aaaagtagcc tatgagagct cagcaacaat ctgtcataaa taaaatatag 13860
tggaaaattc tgattttaat tacagggcat tagcttcagt atgtcataca aatcctggca 13920
aaaattattg aatcaccaca ctcggaagaa tgttcacaag taattttttt tttttttaac 13980
aaatagatga atcacagata tgacaaaaaa actatttttg ttttataatt taacatcctt 14040
gttaaagtga aacatacctc aaacaattga gattaaaaac agttaatgaa tggaaaacag 14100
tttaacacat caatgagaga aacaattatg gaatccatca aaaaacacca ttattacttt 14160
gttgatcctc ctctggcctt tgtgatcacc tgaaatcttt ggggtatcaa aaagcaatat 14220
tcttcattaa gctggtttca actttctgaa aagcacttga cagattagct atgcaacctg 14280
tgcattgaca gttcaggcag ggttgctatt tctcctgctc ttttacccta catacccata 14340
tcataaatga gttgcgaaat ttcattgttt tcttcaggca gtcatcttta tacatttcat 14400
taaaacggca ccagacaaaa gttccagcat catctccttg tccaaggcag attcatgatt 14460
catcactgaa tatcactttc atccaatcat ccctatgact gattctcttt agaccacctg 14520
aaccttgctg tcttctgttt aggtgttaat gctggttttc gtttggcttt tccatgtgta 14580
aatcccattt aattcaccca ttttcttaca gttctgtcac acacattgac tcctgattca 14640
ggccatttgt ttttcatttg tttcattgtg atgtaatgaa ttattgtgca ttttccattt 14700
tcaaggccga tttctatcct gacgctttga tgtcttccct ggtttgcctt tatgatttcc 14760
ttccattttg tttatacctg cagtaaattt tagaaaaagc tgactgagaa tatccaactt 14820
cttttgccac acttccatgt tggacttcag attccatcag attccatttt tcctcaacat 14880
tgaacgattc catatttttt ttcctttact tgatatggaa aatagttttc aattaaataa 14940
aataatcgta tttgtttgag gtatgtttca cataaccaga attattaaac aaaaacagtt 15000
ttgtgtcata tctatcattc gttcattttg tataaagtaa agaagatctg ttcgacaggg 15060
gttgaatatt gtaattgatg tgattatttc aacatttcag aaaacccagt taagattggt 15120
atgtgaaaat gctcttctgt atctgaagaa ggaggacaat gactatttca tcccattgtc 15180
tttactgtag aggccaagtc taatgactgt tgtggaatgg attgactatg aaacactcgc 15240
cttgctgttt ggaatggtaa gtataattct aacaggtcta ggaactctcc agcagtgcca 15300
cgtgtgtaat atgaacatat gatatcagat tgcgtggctt gttgaaaaga tatgtgctgt 15360
tacatttaga tgagattgca cttattattt tatctcctaa ccctaaccct accaacccta 15420
atctaccttt gatacaaata ccccaaacca aatctagcaa tgtttcaaat cgtctcattg 15480
tgaaactttg gtgttaactt gtctaaacaa atgccccata gccacataac aatgagctaa 15540
aatctctcat aaaaccctag caatgctcta gcaacaaact ctatgttttc ttcagaaaat 15600
atctagttat ttaatggttt cagacagcat aagaaacttg tctctggtgt aataagatga 15660
tttaatctgc ctgtttggag aaagttgccc tgctacagta tgttcttgac agtctgacaa 15720
gcctctattc caactcttaa ccccaaatat ttagcctctt aggctggtca gcctgacagg 15780
caattagtgt gacacctttc ttaatgtgct gttaacataa tgcttctttt agaaagaatt 15840
cttcaggagt ctaagatcat ttacgttgtt actttgagtc acactaaatg tacagcatca 15900
caatcagttg aaagttctgt tagctgaggc tgttagactg catatgacat tagtccatat 15960
tctacatggt tctgcaacaa agtgtgaccg aaaaatatca gtacaaatta aaacacacaa 16020
gccagtattt ttgccaaagt cccacccttt tcaagacctc tgtttgttca gtgtctgtct 16080
ccatggaaac aaatacattc aatcagcccc catccagaag actacatgaa ggagtatttg 16140
aggaagagca gaaaagaaaa tcagagactg atgatagaaa atgaagcaca gcatccatcc 16200
atttcaaaga ccgattagaa aagagccatt ttacataaaa aaggatagct ttaataagct 16260
cagaaatatt tatgttccac tttattgatt ttctatattt caaagatgtc tgtttctgta 16320
tctgaggccg aaaaaaggga agagaatgat atatgtggca tgaaattgag tgagagaccg 16380
tgtggcattt gagacataat gtgattttat agcaacacat gtggcggtaa gctctaaaaa 16440
tagaaaccat gaagtgttca agtctcataa cccttcctct ttactttcag atgatactgg 16500
tggcaatatt ctcggagact ggtttctttg attactgtgc ggtgaaggtg agttttctca 16560
atcataatgt ttaaaatgct tatttgttat tttattcata tctttaagca agatacagtg 16620
tcttgaccga gagagtcatt tcctcatatt ctctctaaaa tcaggctaat taatctatcc 16680
cacccacctt atatattata ttatacatat ttatatacat tatatatcta cagatacaga 16740
tacctactaa catttactca ttaatctaaa ggtagcatgc tgtctgttat tgattcagtc 16800
tgatatacat tcatttcgct ttatagatgt ccctgttttt gatttagtca atgtatccca 16860
tcatgctact ttactcagta agctttaggg catagaagca gagatttaca atggcagtcc 16920
tgaatatccc tgtcattcac tctcaagcga agtgatgaga atcccacaaa tgttttatat 16980
atatgaaatt tctgggtgaa catcaatctc caactgagtt atgaaaagga atcagacaga 17040
acaaatcttt gtgaaatgat gcaacccttt aaaaattgtg aataaaatgg gtctgaatta 17100
atgaaagtct aaaaataaat cttacaatga gcttcattgg atggatatcc tgttccttat 17160
tttcagggat tcggcagact gttgtaaaag cccctttgaa acattatgca tgtgctttgg 17220
ccattatgag ggcacatgct tatgtcctct catcccattc atgaatatta agagggttct 17280
gaacaaggac atgttccaca aattaaaata ttgccataga aacaaccccc ttgattgaac 17340
tgttgatgca ttttgtcttg aaatataaat caggcttctt taatctgttt tgtgagcggg 17400
tgagttaaag cctgttcaca ccaagtaatc ctagctataa cgttattagt gtccacacca 17460
acacacaata atgttctgtt tattataagt gtgaatagtg ctttaaatgc tcaagcttgt 17520
taaagcgggg tggattctga ttggctgtca atgtttttat cattcatcag ttaaaaaaaa 17580
agtcagtgtc catatttgtc agttaccata ttaccgataa ggaagttagt ggagtgagga 17640
agtggtgaca tttctttacc acttgattaa aatgattcca gacagcctgc caatgtctcc 17700
atagcgacag gctcttaaag cccagctcct ttgttttatg aatattttct tttcaggcat 17760
aaacattctt ttagcgctga agcccgtttg tacaaacaca ctatggatct gtgtcagttt 17820
ttagactgaa ttcctcatta aaatgtacct ttgaacattg tgttctgagc ccccctcaga 17880
ggaccgctcc cgattctcta tctctgaggc actgttaaat ctatctctcc tttcaagttt 17940
ttttttttaa acatgatttt gttaatgctc ataaacaaag gcaagagatt ttcgtgctca 18000
atttattttt gacccagttc gttttcatca gtgtgaactt gaactttttt taaaccaata 18060
atgaagtgtc ctcagcagta ttctgtatgt ctccacacag gcgtatcagt tatcccgagg 18120
aagagtgtgg ccaatgataa tgattctgtg cttaattgca gccgttctct cagcctttct 18180
cgataacgta acaactatga tgcttttcac ccctgttaca atcaggtaat ggtatctctt 18240
cttaaaacaa tgtctctttc tttctttctt tctttctttc tttctgtctc ttttgacttc 18300
ttttttaaac ttgtataatg attaacttcc aatggaagca tatgtggcaa gcaatcacac 18360
tggaatactt cgtgtttaca atctattgtt ttaagttaga cttgtgtgcc agaatccccg 18420
taaaacctcc aaaataccat tgcttgtaga gtttcattgt aaatgcttta ccgtatacat 18480
gactcttatt tttacaaact gagggataaa tccagattct tttctttggt aactgacagc 18540
atgccacaga tgctgtcaat agagattaac ttgtattaaa cctggagcat tcctttaaga 18600
ggacgttgaa gagaagaagt ttgttcatct gaaccactgc taaaaaaaaa aaaaatccca 18660
gaaggccttg gcttttctct agacaggaat tctttgtcag tctgctaaga gtaacatgag 18720
gatgcaataa gtcatgtctt catgctataa acttaccacc tcattgctct tctcagctcc 18780
atttgagctt atcttcttcc atcttttcac tgttacacgt tgtctctcaa tgtgattcat 18840
ttataggttt tatatcctga tatacaaaat catttattta gcattgttta agaaaccatg 18900
tgcactgaag caatttgata taatgtcgat agtgtttcat gtcccttccc tgctgaaaaa 18960
aaagacaaac ctaaagacca acaaaaaaac tttgagtaag gatacttttt ttttggtatt 19020
taattttttt ttatcattct actgctaaat tcatccatca aattattatc atcttagacc 19080
ttaaaaatcc ctagtgttgt aggatagaat caatctatat ttcacatagc cattaaaatg 19140
gtatgtgcag cctcagcgtt ttcatgacat tgctggtgag aaatgactcc tcttttttga 19200
ttatgcatcc ccaatggcat cttcaaacac ctttggggct tcagaggtta gagatgcagt 19260
acacacacac acgcagttaa agaacgaaag tgagaaatta gagaattcag cttttcatta 19320
acagttacaa atataacaga agtaaaatgc atgagtctgt gtataagttg cagctacaat 19380
gctaggatat tgtggtggtt gtcatgttgt tgctatgtga ttgttaaggt gttctctgtg 19440
tatgtttttt tgcacgtttt actgtatgtt tcaccaggca aaaatcatga aagtatgctg 19500
gattagaaaa acaatagcac accttgtctc aaaaattact agaaagcatt gatctgtctt 19560
gatgaccact tggagactac tctatgtaac atggttgcat tacattgatg ttccaggaac 19620
atcggtccta atcatttttt gtgatatctt ttgtactcaa ggttatgtga agtgcttaat 19680
ttggacccca ggcatgtcct aattgctgag gtaatcttca ccaacatcgg aggagctgcc 19740
actgctgttg gagatcctcc caatgttatc atcgtatcca accaggatct gcgtaaaaaa 19800
gtatgtcatt attttccacc gttcttactt gatgctgggt catttatggg tggacggata 19860
ttgtactgct gtcttgtgcc tgttgagagt gatttaagaa tgatagactt cactgtcact 19920
atcgactaaa ggctagaaca ccatggcatc ctgtcttaca cttaactatt aattatgtag 19980
gaatacttct tgccagcttt agccgcactc tgccaaagtc cctttctctc tgtccctctt 20040
ttttttctgt cataatggtt taatctcaaa cctgtatagc ctctctttat tgagccttgt 20100
gtaatattgg tttgactgaa aaggtggtgg gacattcgag tgtctaccag tttgtctttt 20160
tgtagtcagg tatgttattt tattactctt atttaggatt atgggtttga atgcagtttg 20220
aatggctaac cctttgagtg catttcatat cacaacccaa gtatgcgttg cgttctcggc 20280
attgccacaa gcttgcatta gcataaactg tctgcttctg cagctaggtt ttctctttta 20340
gggacagttt gaagcgaatg atgctgagca agtaagatct cataagtgtg tttacctgaa 20400
taataacaaa tcagattcaa tagtaaagac atttgaagct agctctatac ccccatgaga 20460
attattattg tctccatagt gcaagaacac acatttaata tgttcagcgg gactgtgcat 20520
tcagtgcttt agccgagcat ttgcataaac tatatttcag gtctaaatca tgcagctttt 20580
tgaggtgtgc tgttcccttg tgctttgcaa taaaacagaa aaagaaaatc ccttagatgt 20640
gcattcaaat tagggactag attgaggaaa tcatacagac ttgtgctgga tccaaaaatg 20700
catacttcca tactatgtag gcagttatgg gtcgatttct tacacatttt agtccattaa 20760
cgattaaata ttacatgata aaaactgtag ttagtagcgt aatctaggtt gcacatttta 20820
ggtaatgtaa tcttgctacc actttagatt acttttagat taggacctcc tttagctcac 20880
aaaacatgca agcagttagc atggggtttg ctacacaggc ccatacgcag aaggctgcta 20940
tgaaatagac tgtgacacat tgccctggtc accactgatg tagctgtaat aatgtgcgac 21000
ggtctttgct ctcctctggg atcaaggagt tgcggatgac ccacgggtgg acgacagttc 21060
atcgtttggc catccatgta ccacttttga tttaaactta ctgccattgt gtgaataata 21120
cgttaccatg taattcataa aaagttactt taaaccaaat acagtatttc ggatgcagct 21180
ttgatattgg ccagtaggca aacattctag taacaacctt gattcctaac cgcttaggaa 21240
tgcactaaaa acatcttaag catggccaaa gcaacagctt agcaaccaca tatgatggaa 21300
agttctcctc ccaaaaaaga ctgtgtgtta gtgtatttgg tcaaagtgtg cgtcagtaag 21360
tatgtgtacg agtccagcta aagccctgaa tgagacacag aggatgagac ggagctcttt 21420
catctccaac tccggatgct gattaaagat gctttctttg gagccactct accctgcagc 21480
tctttctgtc acacactacc gcagacacaa tgactaagac aaaaaacgtg tgtgtgtgtg 21540
agtgagcatc agtgcaaaaa agaaagggag cagaaaaagg gtggctataa aagtgtaggc 21600
gatccatctt tttctgacat tctatttaaa aggctacatg ccaaaagaac aactatatgc 21660
ctaaaaacct atttgaagcc atcaatattt atgtcaaata aacatgtcag atgaaacgga 21720
ttttcagcac catcacactt tctgacagag atggttgaat tattgtgtga agcaaattag 21780
ctgttttaat caagtgctgc tttatgtttt aagagtgctt taaagagaga atctcaaggt 21840
tggcttgaag ggtcatgcaa aggtgaagag tggagtcttc gaatatgtaa tgtttttagg 21900
aattctgggt ggtctaaaca ctccaccagg aatcaaagca aaatattatt agttagttta 21960
gggctcattt tcatctaaat caaaacatct gttgacctaa tctttttcta taactttagg 22020
gcatacaatc aaagtcaata tgaaaggttg tttaaatgaa taatcatgaa aaaaaagaag 22080
aagctactaa caaacaaaca aacacatttt ttctactttt taatccctgc attttcagca 22140
acttcaaacc acagctggct tggcatttct gcattgtctt ctgatatttc ctaacgtaac 22200
attattgaat tatttgtgaa atcagtaagc agtaagctgg ccattttcaa tggtcttagt 22260
actctttaca tttcatttca aagatttggg gatatcttgg atgtgaaaga tacatcattt 22320
gtgatgtgca caattctgta taaaaaaatt ttatacgtta aaggccagtt ggaatgaaaa 22380
ccaactaaat gttcacaaac atctattatt gtagaacatt ggtaatactt gagtaactat 22440
attcacagtg cattcatgtt tgttaataaa ctaatgtgaa ctactgaaaa tcaaatgtta 22500
agaatgtatt agtatatgca gaaattgacc ttattctagg ttaacaaatg ctgtaaatgt 22560
attgctcatt catttttaag cccgaattat acccaaaaca tttaactgaa cctaattgta 22620
aagtcttatg tattctttgt aagaaaggtc actaaaccca ttaaatccca ccaacgaggg 22680
caacttaaat gtttcatgtg aagttcaata gttaccatca cagttttcat ttagttattc 22740
ctcaaactct tccatcagcg acagaaaggt gcctggttta aaaggttgta tcttcagctg 22800
gctttcagag ctgaaatcac tgtggggttt gagttaattt atggctcagt agaaacatcg 22860
tccttgcctg tcaaaccggc tgttgcacag gatgatgcag cggtaatcat gcttgagttg 22920
cattttccac atcaaggtca cttcctgctg ggctacaatt gacagtgggg aattttctga 22980
aaaacccaat atccctaaac tcacatttct gacaggccta aatctctgga gggtggaacc 23040
catcagacgt aatgaaaccc cccccccccc cgctctatat tttctactgt ataaacatga 23100
ttttgggttt ccgtcagggt gttcagtgat aaatatgttc ctgtagtgga tgcacagtgg 23160
agggcctgtg actatccatg tgtgtggaag tgctggacag attcatccat tctgttccgc 23220
agggagagat tgcatctgct gtaattactg acatggatgc agtggtttgt gttatctctg 23280
tgttacactg ccagatttgt ttatatttga aagggcttct gtttgtgttg acaacatgca 23340
gataatgaat ggatatacaa cttcatgtgg aaaaaatgac acacaacaca cacacacacg 23400
cacacagttc aatacttgcc atttgcttat ttgttaattg ctttgtgcat tgaattgata 23460
tgacttttat agaataacta agagattcct tgcactatga aacaattttc tggtttacac 23520
gtgtctatgt gtgtgtctga ggactcgggt tcctgatgca ataaaggtag gagtcaatga 23580
aactttgggc tctctataaa tgactgatcc aaaactattt ttaagctagt gcaaacaggt 23640
gcttatatag tgctgtaatg tagtttactg atccattgtt tgagcttaaa aatgatttaa 23700
gcaattttcc tatttctgta cctattagtt tattgaggta tcacaccatt ttattcaata 23760
ttttttttta ttagggctgc atgagaaatc gcatgtgata ttttttgcgc atcttgtcag 23820
taaagccggt tctgtaatca gcagtaaatc tccatcacct gcgctctttc acatggaata 23880
gcattaacta cacagagctg tcgtttacta acaagctgtg gaaaaatacg atcatatttt 23940
gtgcatgttt tgcgcagctt gtcagtgaac aacgcccagt tatcgtgcaa ccctatattt 24000
tttatttcat ttaagttttc tgttttggca ccaaaatatc acatttaaac tttcgacttg 24060
ttgaaacatt atctgtatgt atttctctgc tctattatgt aaattaatga gtgtttgtat 24120
ttttttttgt ttgactcatg tctatttgct tgtatataac cgaggatcta atttgattgt 24180
agtgaagcca ccaccttctc caacagtcac ttaatccgtt tattaagata atcagcctca 24240
ggatctttag agcttctgga tactgaattg aagctctgcc atacaaatat atggttgaca 24300
tggcacaata cagtttatta aaatgcactg agctagaaat gtgctttact aatccacagc 24360
ttcaaaagtt tactgtacct tgacttacaa aagcaaataa tgttatcctt aagacgtttt 24420
tgaaagatgt caccaaggct gcttttatat ttcaaataat attaatatat aataaaattt 24480
aaagaatgtt tcgaatttta aaatataaaa aaaacaattt attcctgtga cggcaaagca 24540
gaattttcag gcaacatttt actcttcaat ataaaccatg acacatacat acatttattt 24600
agaacagcat acatttgcaa catggtaaaa gactgaacag tcacttttga tcaatgcgtt 24660
catgtttttt tctagaaaaa gttcacaatt ttaatgatca aattgacccc cccccccttt 24720
tttttttact aggtttttca tagttttatc aagtatggca ttagagaggt ggtagacaag 24780
tggtagaaat ggtaaaggga ttaggaaatt aaatcatgat ttaagatttt attaatttcc 24840
ctgacttaag gcctagaaat cacatttttt aatatgaaat ctttgaagtt tccaggtttt 24900
tcatgacggg gtgattcctg aacttagccc gtcctgcatt tcccaggcag cagtcagtca 24960
tgatggaaaa tcttgtacat gtgggctctt tgtttatttg tttttttctc tgtttgtttg 25020
ggctgtgcga gtcgaaatgg gcctcctcat cgttctcgac aggatcacta cagcaggaat 25080
gttgccattt ggcctgtcaa gcatccatct gtggagctct ctagatcaga catttgagat 25140
tgggcagaag gagtgtttca gggtcgctga ggagacgttt catatatatg ctgtgctctc 25200
tctctggcat ccactgggcc gtcagtcaca ctcccaggaa tctcagctgc caatcagtgc 25260
ttctccaggc cccaggcaga taggccttgg cgtactctgg tttgactgtg gaccctgact 25320
gctcactaat cagctagcgc caacagtgaa ggcctttttt ctcattccct cttttctccc 25380
acttaccttg ctttttgaag tttctttctt ggttgataaa agtgggacag tgacaacaga 25440
aatggagtaa gaggaggtct tatttacaca ctattgtaat tcatgcaaca ggcctgcatt 25500
caggacaaaa caaatgaatc tacaaagaaa aatctccaaa cactgcctat tgtttgcagc 25560
tatattactg accaagtatt gaatacttct gcatctactc tatagtgcat tcatctcaac 25620
agcacaggaa atccatgagc agtaaagcag agaaccactt taatataatg ttattgacag 25680
attccctcta gcccagcttg ccccaatgag tctgtaagga tatttcttat tttcttatct 25740
tataagcaga ttcattgaaa agatcagatt taattagttc acaaatcgga tatcactttt 25800
ttgcaatgag gttgcagtgg tcctttcatt tgttctccct gtcttttcat gcatttctct 25860
ttttctaatg tgattagaaa ataattctaa ataataataa taattctgtg tgctttcctt 25920
taaaacccca ttacaaatct aatcataggg tacacaaatg gatgtgtgtt ctcttgaata 25980
cctctccctt tctcacacat acacacagag agacacacat tttctctctc tgtctctctc 26040
tctctctctc tctctctctc acacacacac acacactctt ttttttcctg atctcctgta 26100
gaggtcactg tataccagtc ttcacgtgtc gttgtctcca ttcacatgtc tcatgttggt 26160
atatgagatt ggacatgttg tttgtgtgtt gtttgcttac tcacatctta aaaagccaaa 26220
agcattattg cccccccccc cacaaatttt ttaccagccc tttgtttagt ttctaaaaag 26280
tacctctaag ccctgggtgt ttgccaagcc tgagtaatgc ggggagccga actacaacga 26340
tgcaattatc ttgtattttg ccagttcctt tacaaaatag aagagactgg gtctagctgt 26400
cacatttttt actaatttct tatatttctg tataagtaca aaaaagaaag tcttggctac 26460
aataaaacat tattgccatt gttattgccc aagaaaaaga tacagtttat ttaacacctg 26520
ttggcctttt tttaaatatt ggtgctaagc tgtcacagtg gtaacctgcc attagccttt 26580
tatagactga caatttatac aattaaacag ttataaagca caagcaattt gtgaaaaagt 26640
atagcttttc actaattaat attgtaatta ataaattaca ggtgcatctc aataaattat 26700
gatgtcgtgg aaaagttaat ttattttagt aattaaactc aaattgtgaa ccacgtgtat 26760
taaattcagt gcacaaagac tgaagcagtt taagtctttg gttcttttaa ttgtaatgat 26820
tttggatcat atttaacaaa aaccccaatc ttatcaaatt agaatacttc ataggaccag 26880
ttaaaaatat attaaaaaaa cattaaaatg tttttgtgaa ttgttggtct tctggaaagt 26940
atgttcattt actgtacatg tactcaatac ttggtaaggg ctcattttgc tttaattact 27000
gtgaggcatg gaggtgatca gtttgtggca ctgctgaggt ggtatggaag cccaggtttc 27060
tttgacagta gccttcactt catctgcatt gtttggtctc ttgtttctca tcttcctctt 27120
gacaataccc catagattct ctatggggtt caggtctggt gaatttgctg gccagtcaag 27180
cacatcaaca gcatggtcat ttaatcaact tttggtgctt ttggcagtgt gggcaggatg 27240
ccaaatcctg ctggaaaatg aaatcagcat ctttaaaagc tggtcagcag aaggaagtat 27300
gaagtgctcc aaaatttctt ggtaaacggg tgcagtgact ttggttttca aaaaacacaa 27360
tggaccaaca ccagcagatg acattaaagc ccaaatcatc acagactgtg gaaacttaac 27420
actggacttc aagcaactgg ggctattagc ttctccaccg ttcctccaga ctctaggtct 27480
tggtttccaa atgaaataca aaacttgctc tgatctgaaa agaggacttt ggaccactgg 27540
acaacagtcc acatcttctt ctccttaggt aagatgcctc tgatgttgtc tgtagttcag 27600
caattccttg acacgtctgt gtgtggtggc tcttgatgcc ttgaccccag cttcagacaa 27660
ttccttctga agttctctca aattctcgaa tcgattttgc taaacaatcc ttataaggat 27720
gcggttctct cgtttggttg tgaatgtttt tcttccacag tttttccttc cactcaactt 27780
tctgttaaca tgcttggata cagcactctg tgaacagcca ggttctttgg caattaattt 27840
ttgtggctta ccctccttgt gaagggtgtc aatgattgtc ttctggacaa ctgtcagatc 27900
agcagtcttc cccatgattg tgtactctag tgaaccaaac tgagagacca atttgaaggc 27960
tcacgaaacc tttgaaggtg ctttgagttg attagctgat tcgcatgtca ccatattcta 28020
atttgttgat attgtgaatt gttggttttt tgttaaatgt gagccaaaat caacacaatt 28080
agaaaaatca aagactcaag tgtatttata aaaggtattt ataaattatt ataagttaag 28140
aggactttaa actagggttt tgaaaccgac atacaaaaac aagcatttgt gcctctcttt 28200
gtaaactgtc tttgtactac ttacgtactg tacacatgtc accatgtaaa caagaaaaga 28260
tacccaacta caatacgtta tacaccagct ttatattgga agataaattg ttggattaga 28320
tttcaagcga catagatcta ttttacacat cactatcagt ggtgccaaaa tgtaatgcca 28380
tctggttatg atgagaaatg gggtgggctg cacaggcaag aaaatataat ctaaagctag 28440
acgttcagtc gagaggacgg tgtgctcttg atatgaatta aaattaataa atagtcacga 28500
gcattttaag aggatttgtg ccacatacaa gtgcttattt aaatcttata taagtgttta 28560
atgtatcaag atgcatgcat taaaatgctg aatatgattc tgttgatgag atgtaatcaa 28620
ggcctccatc cacattatat gaagagccag taaaatggat gtgatctcta cttattgctt 28680
agaaaagatt tcatgaaata ctgcagcaaa ttaattgcac agtttttaaa agggtgaaaa 28740
ttaacccgcc ctcttcttcc tctaggggat tgactttgca gcctttacgg gttacatgtt 28800
cctgggagtc tgtctggtgc tgctgacctc atttcctttt ttgagaatgc tgtactggaa 28860
taagaaactt tacaacaagg aatccagcga aatcgtgggt gagtattcat ttattctgct 28920
ctatttctac gcaccaggtt tcctaaaatc atacagaact atcctcaagt gtatgtactg 28980
tagagccact ctgctttcct ttgtttttga ttcaagctct tttgttctga caatgaaaaa 29040
tgtattcata atcccattga cctagatcgt aaagaatgag caatcatttc taaaaaaccg 29100
tagacaccag tggttaaggg cacacttgac cttcctttgt tgacagcagt tcttcctata 29160
tgagcacgag aatgagagtc atacaccatt ctacactatt tacaccaaat ctcatatcct 29220
atccaaagct ccttacattt ggcctttgag cccctgtgac tgggataggc acagcctacc 29280
ctttaatgga tgattataac ctcggcaata catcaatttt tcatccgtcc ctccttctct 29340
cccacatccc acgatcatac tgatgcattt agtctctctg tacccttcag gctgttttcc 29400
ctgatatttc cattattctt atcggatgag cctgtgctga aagccttaac gcatctgtat 29460
taaatacata aatcctgtca tagatgacct ctctcaagac ttacacatat gcacagtttt 29520
cagacaggac atgtttgagg ggtcttggtt ggttagcatg gtccatttaa aataagaaat 29580
tattctattt ccaaggaata tatagttatg aatcatttat ttacagtgct cttattttac 29640
ctttcatgac acagctctaa taaagggctt ggaaccattt gtttttgtgt ggttaggcaa 29700
attaacaggt gattagctca aaaactctgt gcccagagct gcctgtgagc acttgtactt 29760
tctggtgtca acggttttaa atctacaata tttataattt tcttactatc tagaaaaaaa 29820
ggttctgtgt taaagcatgt ttatggtgta ctgtcatcag cctgtcataa tgtatgttgt 29880
acttgtatct tgatatccac cattgtgtga tgcttgcttg aaatgggtga tgcgtcagag 29940
agttgcatag ttatgacatt ttaaaagaac agggcacatt tagcacaagt gtgaaggtgc 30000
tagcacagct agaaaggccg ttaaagccat caaagccatc atgacaggtc aataccactc 30060
tcacctagtc atcgcttctt caccgcctcc actgaaagcc agtctggcca gaacagaatt 30120
ttgggttaat ttccaatgta tagatgatat caatgcagtg taaatttgtg aagataaatt 30180
tacttattta tttatttatt cattaattta tgtattgttc attttttgta cacttatgaa 30240
aaattgaaaa atacaaacat aaaaattagt taaatttatc aaaagcctat tactttgact 30300
tttttgggtg aactattcct tatttacagt cacatcttta tatatacagt ggatatagaa 30360
aaaaatcacc cctctttaaa ataatccaat ttttttgctt tttagcctga aatgaagaca 30420
tatacaatat ataatattcc tcaattaaag tcacattttt atatatacag tgggtataga 30480
aaataaccat ccctctttaa aataatcaat ttttttgctt ttttagcctg aaataaagac 30540
agacacaata taacacaaat atgtccaaaa aaaaagaaat aaaaaaacgg aattgctgag 30600
gtgataaaag gatcaacccc cacccccctc caaaaaatga cttgtaaact caatcaggtg 30660
gagctaatca ccttctcaat ggaacacaac gctatttgac tttcaaccgt aatcggctgt 30720
ggtcattttg attagctcag catgaaaaga actttcctgg agcatttcag gtcttgatag 30780
tgcaactgaa gcaaaaaatc aactactgta taggtggcaa aacactgtca aaagatctcc 30840
aggatagagt tgtggacagg cacaattcag gagatggata caaaaacaaa aaataaataa 30900
ataaataaat aagaggcttt attagtgcct agaagcacag taaagtcagt tattaagaag 30960
cagaaggtat ttgataaaac acagtctctc cctggatcag gatgtcgctc caagtccaaa 31020
ctggatgaaa gagtctggag gaaactggtc agagaggctc ccaagagtcc tacagcaact 31080
ctaaagtagc tgcaggaatt tatgacagag tgctcattgt gtgcgtatga ccacaatatc 31140
acaaattctc cataaatgtg gtttgtaatg gagggttgca agaaagccac tccacaagaa 31200
atgcatgctg tcagcctgag ctttaccaaa acacaccttg aagattctga ggcagatgag 31260
actaaaatgg aattatgtag actcaaagcc aaacgatttg acagctcacc atccaaataa 31320
caccattctt ccagtaaagc atggaggtgg taatatcctg ttatgaggtg tttctctgca 31380
gtagggactg gagcacttgt caggatagaa ggagacattt atggggcaaa atacgttcaa 31440
attcttgagg aaaatctgct gccctctgcc agaaagttgt gaatgggagg aagatctacc 31500
ttccagcatg acaaagaccc aaaacacaca ttaaaactga ccacatggtg gttaaaggag 31560
aaaaaggtga atgtccttgc atggcctagt caaagcccca ctgaaaatct gtggaatgac 31620
ttgaagactg cagtcaacaa acggtcacca tcaaatgtac tgtacagtaa ctgaacttga 31680
gcagttctgc aaagaagagt ggtcaaatat cgcaaaatct agatgtgcaa cgctagtaga 31740
gacatatccc aatagactta aggctgttat tcaagcaaaa tgtggggggg atctttttcc 31800
aactccgtga ttgtggttgt gttttatttt attttttgga catgttggtg ttctatcttt 31860
tacttggatg ttgaggaaat acagctggat taaacaaaaa ctttgtccat tttcatggct 31920
gcaaagcaac caaatgtgat tattttacag gggggggggg gggggggggt gattcttttc 31980
tgatcaaatg gttttttgtt ctttttattg aattattcgc tgtgtaaata aatagaatta 32040
ataatcagat gagtcttcta gctccagttg tcaatgtctt tccacagatg gccattagcc 32100
tcttgagcag ctgctccctc tgctccacag agaccttctt ctcacatctc ccatacacct 32160
cacacctgag ctctccttca cacacctgac aatatgacaa tagctccttt ataacaaacc 32220
actcatttca gccattcaaa ggcatttcag ccataaaagt attcaatgca attcagttca 32280
attcacattt attagtataa cgcttttcat taagcatatc gttgcagagc agcttcacct 32340
aaaattaaag tttctacaat aaagagtagt atcagtggtg actatgtcaa ggtgataaac 32400
atatggcaga aatgtctaac tttcttccat catgtaacat tgcttgaatg gacctttttg 32460
tggtaaatag tggaagtttt gagaacttca gattacacag acaaccacca gtcgaccttg 32520
ttgatacagt atatgtgtaa taaataagag agaaacttta atttttttca ttcttgtttt 32580
tgatgcactg taaaattatt tttgatagct gtaaggatca ctggattacg ttttacaaaa 32640
aaaaaaaaaa attattttga caaaacacta ctttagattg taatggcttc acatttaatg 32700
tatctaattt agaacagtga tttttaagat ggttgacatt tatttctggc attaaattat 32760
tattattatt ttttgcctat atgaaaaagt tataacagca ttatcagtat ttgaatttag 32820
aaactgctta aagaacatct gtgttgtttt gaaaaaaacc tgctctaggc tacatacatg 32880
gatgcttcac atctacagta gaaccttaat tactgtacat gtatgcatgt tttgtgcctg 32940
tcattttata gataaaacaa gatgagaaaa aaaaagtgca atttctttct cagaaggcag 33000
gaagacacac tttatatgtt ctcttacacc actggctttt gcccactgtg agggttgtct 33060
ttgagacatc atcagcacgg gacaagcacc atccagaatg ccaattattg ggttttcggg 33120
tggctaacac aaagaaacag tgctggtcag tgtggagctg ttgcaaagtc ttagaactct 33180
actctataag gaacagggac ttaaatgatc ggtttgccgg ttccccaggt acatgctgtg 33240
cctggacgaa agacctccac taggcctgat ggtgaccact caatgccagt ccaatttcta 33300
attctgtaaa gcctgaagtc cccacagagc ctcactttta aaaaattcaa acctgctgtg 33360
cggctgatac agaattccag gctctcggca tgatgcatta ctgtgtctat tgtgatcagc 33420
atgttttccc cgtgtcaatt agcttctggg aagctttcct agcagactcc ccatcgcatg 33480
gtgaggagcc atgctgaagg actagagcaa aatcttgcct ctcctatctc tttatttttt 33540
ccttctgcct tatcttctcc ttccatactt tctccattct ttctgtacag taactgcctg 33600
gcttgtgctt catcctatct ctctcgttct ttctgtctct ctatatatat ctatctgtcc 33660
gtctgcctga tgtattttgt ttttatttat ctgtttaatt gtttgtctga ttgtttgttt 33720
gtttttggct acccttataa agtaacacaa tcattcatct tataagtgcc ataataatta 33780
caattgtgga gagaaggtag ttttagacaa ttcgtttttt agtaattatt agtaagttat 33840
ttgtcattac taagataaag acatcaaact aagatcttaa gtattatgga cttttatttc 33900
aaccatttat ttttaaacca taacattttg atattgcgta aggcattaag atgagtgttt 33960
ttcttggtaa aaggtcgctt gaaaacacaa tattaggtca aaaatataaa ttaagtcaat 34020
aacttggtat ttaagtcaat cttagatctt atttttttat ttagataatt ttttttagat 34080
tggactgtct gcattctagc tttactgtat ctgggaaaat gtatacagtt cagccatatt 34140
catacaatta attggcataa aggtagtgac agatatttta aagatgtttg aggtgaattt 34200
gaaaaatatt gtgaatatgg gagcgaacaa aaatattaca atcccttcct tattcttttt 34260
ttctggattg gctctgttga acatacatcc ctgtttttaa taggtcttgt tatctgtttc 34320
ttccgagttt tttggaatag attttaaatt cttatcttcg tatttgtctg ttctacagct 34380
gaaccccttt atcttgtcac gatttatgtc gccctgcaga actgaagcat gagattctgg 34440
tgtggaggca gacagcccat cgcattaacc ctgccagcag agaggagtct gcagtcaagt 34500
gtcttctcat gcagaaggtg ctcaatctgg aaagcctcct gcacaagaag ctcaagacct 34560
tccagaggtg ccatgctcat gctcaatcca ttcttttctt tgtctgtctg gttaaaaata 34620
caagcagtct gtctacaccc tgcatagtgt ttgatttgaa atcatggatg tatttcgaac 34680
ataagtgtat ttttgttttt tgttcttgtt ttataggctg gtttttggac tttttttact 34740
tgtgttgtct aaatgtcatg aggataatgg tggaaacaac cgaaaaacaa caaattaggc 34800
tatacctaat gcattcctca agctttcttt tactattttg atagtgcatg taatatgagt 34860
gtctttcttg gtatgagttc acttgaaagc actctattag ggccaaaata tatccattcc 34920
cactgcatga cacctgttgt gtctgacagc agcatatacc cagaagccca ggatgataaa 34980
tgagcaataa ttaacctgta gaaaagtagg taattgttct caattgtgtc ggctctctaa 35040
agctcttgta gagagctgaa attttaatca tgcagaataa ttttgttctc aacagttccc 35100
ctgttttttt tttttttttc ggttttatta taaatgcttc ttttaactaa agaaattcga 35160
tacgttatgc ttgtgggttt gtggatcttg tggtttgctt tgatgccaga tagaataatc 35220
acagaagcca tttacagcct cacatgctga gtagaaaagg tttggggtga ccacatgaaa 35280
ttacaactcc tactcatttg caggtgtcca tgctggctga aaggatgtat taacacactc 35340
cattctgttt tatttcttta ttttcacagg caaatatcac aggaagacaa aaactgggaa 35400
cacaatattc aagagctgca gaaaaaggta aaacaaatat actctggctt gtgtatttga 35460
taaaatatca ttaattggag gagtttaatt ggacgcgtca agaaaaaaaa gatatgtttc 35520
ttctaccttg taaatgtgtg agtgctgtta tatgattagc atcatttttt ttatcactgc 35580
tatatgtgat cctatgagaa tagacctgca gatctcatta ttgcttctta ataatactaa 35640
tactgataac aataaataat gaataatgaa tgatttaatt ctaaataata tattaatcta 35700
ataattaatt gatatggtcg aaatgaagaa attaactttt ttctattgta caaaaataaa 35760
caaaattgtt aaatatcaca taatattact atgagctgat gctaaataga aaaaaaaaag 35820
gaaattttgt tattgtataa agtgttaaag tttacattta tttatttagc agactctttt 35880
atccaaaatg acatactaat gagaccgtga ttatagtttg gtttctaaat atcaattgaa 35940
ctgtacagta aaactcttta gagagcataa tgggtatgtt tctttctgtc cttcatctaa 36000
acacgtcttt tatggtcttt cacagcacag aataactgat aaaatcctcc tggtcaagtg 36060
tctgactgtc cttggtgtgg tcatctttat gttcttcctg aactcctttg ttcctgccat 36120
acatctggat ctgggtaagc gagagacaaa caagggcgca gataaccagg attcatctgt 36180
ttctattgct gatccggccc tgctatttac atgcctcact gtataattat gagggcttgt 36240
ttcctctctg ttttgagcag aggaaatggc atcacaagaa tatctcgctt cttctttaaa 36300
tgatcaaaac tgtgccaatt cctctaccac ggagcgaaca tttcatttta tgtgcatttt 36360
attaggcttc gtagaataca attagtgaaa caaatgatat tctagtaaag ctggccactt 36420
tctcgcatga tctaattggg gtgtgcatga atctgtcaat gtgttgatgt cgtaattgtt 36480
tgcagctggg ctttaaatgc agaaaaagac acaaatgcaa aaccacaaca atggagtagc 36540
gtgcgattaa ataagacggc tagtaatacc caccccaaaa ttagtctttt gtttctgttt 36600
agccttcctt tttgctctag gtttgtcgaa ctggtttatg gatgtgttta ttatacagtg 36660
aatgagaagt caattacaga tggaaatgag attgggaact tcaccaaaca cattagcgag 36720
aacgagttgg tcaatcagag aaggccggcc acacagctca ctaaggtggt tgtgttgttt 36780
gggtctgatt gtgtattgac gatcagttct catttgtgga caggtttgtg gaaagatgac 36840
acatgaatat tagtttctaa atgatcatgt tctcatctcc tcattcatag aaattcatgt 36900
tttttccccc ctcttcaagg ctgtgtacat aattaattag caatgattga aaaaataatc 36960
actgtacatt accattttga aaaaaacagt gtggtcctgc tttcaaaatc tcttcagtgc 37020
ctcgttctga tcaaaaccag ggtcggtcag catgggcttt aaatgagtgt cattagactt 37080
tcattaggtt gacacatcac cactccattt gacctatgat attgattatt taatcatggc 37140
cgaggatact gtgcagcctg ctggagggca atgaagcaca caggatgcac tgtgctcaca 37200
gagctccacg tctttccaac gaaaagcaca ttcgtgaaaa ttaagtgatt tttaagcctc 37260
aaggccatct attttcccag aaaatcatgt aattacagtt cgattctgtg ataactgact 37320
ggtgaacttt tagtacattt ctgtaaaaca atgctagtag taacagtggc tctgggagtt 37380
ttcttgattt ttaggtcact gaaaagctgt tataagaaaa aaacaaaaaa ggctctgaag 37440
gtcatttcta taggtccata taaacatttc acatgtaggt cataatggaa tttcaaggaa 37500
atatcaataa ttttctcagt gtgagatttt attctaaaag taaagatatt ttcatgctca 37560
taaatcccaa agagctcatg gaaaacaaca actgacattt gattcaagaa acttttaatt 37620
tttttattat tcattcgtaa taatttttta tgtagtttaa atccaagttt ttcttgaagt 37680
tgctaattga tttggtagtt gtcccgaaat atactgacac ctagtggcat ggatacagat 37740
ttagaataaa gcaaaaatgt taattaagca tgccaaaagc catgtaacag gaacttttga 37800
gtgaaaacga aaatcagggc taggtcgtgt gatcaaatca tgtactgtaa attaagcagc 37860
cttactatct tatccttatt atatttattt tatatgtcat gagtttttat ctcatgtgaa 37920
tatgttttca acccatcatc tttcaccatc tctgtttgaa acataaaata gcaggttact 37980
agcaaaatta tttcttttgc tttgccactg cagaataata aatctgatgg tttgaggtat 38040
gcatattgat ttttgtaatt tgttttacca aaatctcttc tgttaatttc taatttctaa 38100
tctgaaattc taattaattt cagggtaaaa aataaataaa tgaggaaatt attacattta 38160
agggccacgt gcttattaaa tattactaat gtaactcatc tcttgatatg gtcatttatt 38220
tatgaataaa taagttacaa tccagacata aactctggcc agcacaagag ctgtaccaac 38280
caaataatga atgaggaaat ggtggaagat taatcaaagt agaaaatgca caacagctca 38340
tttcttccaa gatatttctg agaaagatag agagttcttt ataaagaagg tgcttgtgga 38400
aacagatttg ctttaaaatg aagaacatga tgaggtggtg tttgtgtctc actcaatggg 38460
gcagaatggc tgtgttgttt tgggtatgat gaatgagcct cccaggcttc tcagcaaact 38520
tcttttaatt gcagagtcct actttctctc tgtcgctctc atttttctgc tctgtttttg 38580
ctgcgcactg ctgaaggcct ccagttcctc ctccatcttc agttggatgc ctcgggggaa 38640
tactgaagca gaaagcaaat caaaagttac ttttttggac ttgttttgtg acaaaactgt 38700
cccagtgcca atgtggaaga agtctgggat ttatttcaca ccatgcatga actacagtgc 38760
taatgtgtgt gtgtgtgtgt gtattgtgcc atccaactga gttaatatgc ttcacttcta 38820
aagaaaagat gcatagtata tataatatag agtacatgta atatttgttt acttattgag 38880
gtggctgacc ttgaggaata tttaaggtat ccaagtgaca agaaagttgt tggaccccga 38940
agccctttta atatctcaaa aacatgctta taatttatgc atcaaactga tccttcttga 39000
ctttttctaa tcttatgaga cccaaaacaa actttttgat cagagtttta aagagattaa 39060
agcttcatta tttcccttct cctgggtttt cattagatca gaggatattc aaagactctg 39120
aagggaaaac cgaagcttaa ttttggaatt aaatgatcat ttttgtaatt ttgtttacat 39180
atacaccttt ggggtatcag ccaaataaga agggcataac agatatttga attaaacttg 39240
tcaactacat tagtgactgt tacacttcca tttttactat tagatttcag ctttgtacag 39300
tatgttgcag attcgtctat acatttccat tatctccatt ctgatccatc catcatttgg 39360
ctattcttaa caccattgcc gtcattacct cgtttaaact ttctttaaat gaataaattc 39420
tccttcacaa ttacaataca tctgtgtcct ctgtgtgact gcagctggtc ccttctctgc 39480
cttcttctgt tctttctctt cctgtctttg gctcttcctc tgttcgtcct tctcatccct 39540
tattaaatga tttcccacgg gcaatcttca gcactcacct gcttaatcaa attttgctag 39600
aattggaagc atactgtcgc cccctcagct atgatttata gcgtatcggt ttgttgcagc 39660
acttactgac cagtgttggt cataatccca aaagtatgtg tgcacgcttg aatgatgttt 39720
tgtgctaaat ttgagaagct tgaatagtga ctgtttgacc attgtccagc tcgttttaat 39780
agaggcactt cacacactgg cattgctggc taaagtccaa agcctctggc tggcttacag 39840
gaaatagtct gctggaagtg gggtctttag ataattgctc agttgtttgt tatcctgctt 39900
tgagtgggtt agtcttttga catttgtgac tatttctgtt gtcacagtgg tgggtttttc 39960
atgaatttga agtgtatgca ggttaataat gaaaccgtaa aacaagtatt ttcccaacta 40020
ttccttcatt tctgaaggaa agttctcgct gacaatcagt ttttctgagc aacattttat 40080
ggctgaccct acttttttgg gggcccaagc actggttatg gcaaatgatt ttgcttaagg 40140
acccagattt tactcattta atttgcaaga atgtggccgt ttttaagttg gaacatactt 40200
ttgcttgctt ttaccatgtg actgatgaaa ttatgccaaa aaaatccaca aaggaggatt 40260
tgttacacta taaattagta cgtttattgt taatgcttag catttattcc ctagatctgc 40320
cacccatttt ctttttagga ttgtgacaca ccgtgacagg atctggttcg tgattttcca 40380
gaggaaggcc ctgtcttatt atatgaaaaa taaatgtaat ttcagcccca aagcttttat 40440
agtgtgtgtt gtacatgacc gtctgctcaa cacatgctgt ttcaaagact gaactcagta 40500
cttcctctct acgtgttcct gcttttaact caaggccaac acactcatat acgctacact 40560
aaatgaactc ttcctttctc tctcatatct ttttctgagt acacagagga ttacatttca 40620
atagaaagat taataatgca caacgaataa atgcaaaata acaagaaatg aaatgttccc 40680
tttcaccgct ttgttttggg aaatgatgac gaacacagca tttttcagga aacattttat 40740
atggttgcta cgacgaatgt ccccttaatt gttgctccag taaaacacaa catagagaag 40800
ataatccact acctggattt atattcattt caaactctta ttttactgct tgtaaatgtt 40860
tctcccagtg tgtaagcata cattaactgg gctaatggct cctgttcatt tgtagatatt 40920
tgtactctct ctatctctca actgtcaacg tcaaacagtt gaatgtaata cacaggtcca 40980
gaatatagct tgtttttctg tagctattat attgtgcatg gtcctgatgt ctaaatggca 41040
ctgtaatgga aatattataa ccaccgcatg tgatggcgcc aatggtccat atcctgctgt 41100
attatccatc tcactttagt ggctcataca tttagttcct gacatgctgc atatgttttt 41160
aatcccagag gcttctggga aacagtaagt catcacctaa tcagtggtaa aatatctggc 41220
agtatttcat gacagcatgc ataatgttca gctaatgtcc ttttatattt cacctccatt 41280
cttgatagat atttcagact gagtggatta aaataaacat ggtttaattt agcttatatt 41340
gtatagtgta aaggaaacct ttacataaaa aaaaatgaag attcaggcat catttactta 41400
ccagcatgtt gtttgtttca aacttcatgt ggtggaacac aaaaagatat ttctaaaatt 41460
tacatatcat gtaaaagctg ttcttttgaa ttttctattc atcagataat cctgaaaaaa 41520
aagtatcacc ctttttctca caacaatatt aagcagcact atttttttca gcattgataa 41580
taattagaaa tgtttcctga gcagcaaatt ggcattttag aatgattttg gaaggatcat 41640
gagacactca agacttcgta atagtggctg aaaatcacag gaataaatta catttaaata 41700
tatattcgaa aacagttgtt taaaatcata atatttcaaa acattatagt ttttattgtg 41760
gttctgatca aataaatgca accatggtga gcataagaga cttctcagac atataaaaat 41820
gcatacagaa ttaatcagta tgatatcctc tctcagggaa actgacactt ttatgttctg 41880
tttatgttgt atttgcgatt cccatcattt atttagactg agatacttag atcagtcgga 41940
cacatcacag aagactttaa tgaaggcttt ccagtaactg gcttattatt cttatgccct 42000
gacagcctgt agttcattgt ggcgttgcag atcacctgtg gtgtctgtat attgatgtgc 42060
agagcgatta gtgagtctgt ttgagtggtg gctggactgt gtttctaatt gaatgccact 42120
gtttggtctc tctgttgctg aatgtttttt ttgtgtttgt gtgtgtgtgt gtgagtggaa 42180
taccagattt aggaacactg tggtcggctg atgagaaagt gtttgtggtc atgggaaggc 42240
aagatagatt gagacataac atatgattga tgcactgcat taaccagcca gcctgctgtt 42300
ttccaggatt ccattatctt aaagccttta cgtgcaacaa caggaaataa aatgtttgtg 42360
tgaacagtgt tcttggttct tttccagtga tcttggcttg atgtactgtt ttgtccctca 42420
ggttggatcg cgatcttggg ggctctgtgg ttactggtgc tggctgatat tcaggacttc 42480
gagatcatac ttcacagagt ggaatgggcc accctgttgt tctttgctgc tctgtttgtg 42540
cttatggagg tatagtaatg ctcaacaaac ccacatatcc caatggctag tcatagttta 42600
ccaagatcta tttttttata tattttttta taattttttt atgtgtaacc cagcctttgt 42660
caagcatgaa acagggaaaa aaattcattg ttacagatga caaaatattt aaagtgcatt 42720
gtcatgaaag ataaagtaga aatagtgtat aaaattcact attaaatata catgttatgt 42780
ttatttttat ctatcacatt cataaataaa gaaggagaaa gaccgtgagt gagtgactgg 42840
agattgtgag tcaaagtaag gagaaagtga gcatgtcagc agcagaaatg ctaggtttgc 42900
tgtttgtgtt ggtttaatcc tttgttttgt taggaggata gtattcacac agggaagccc 42960
acccctcggg cccagtgggg agcttaacac tgctccaaga taaactgttt gccctctaga 43020
gcagagccaa cattcacaat cattcatacc agtgtgcact gcaagcgctg agacaaaaat 43080
agatgaatta tgatattcca attccattgt tagaaggatg gaaaatcaga gctgtcaggt 43140
taaatgtctg ttgttttgtt ttatggtcta tggcttgatt ttctctttgg tgtattttta 43200
aggctctagc ccagctgcag ctaatcgatt acatcgggga gcagacagca ggtgttgata 43260
aaagtgagta tatgctccag aggtgtttga tactttgata cttttggggg gatttcacta 43320
ggaatttata tttgcatggg ctgtttgtgc tgctttggtg ctcgactcac taaaggtgtt 43380
atgcaatcag cacaaaatct atccaaaagt ggtattaaaa cttaagtgat atgatctcaa 43440
gtgggaaggt gacacacgct gcttacacct tgatgtaaaa tgcttcagat gtctcctgtg 43500
accactcatg ataggatttt gagggaaagg tctgtttctg cctcagagta tagacagatt 43560
ataaaaataa aaataggaat aaatacattg taagtcacat tgtaagacat tttaggccct 43620
attttaacaa tctaaatgca aagtgtaaag cgcacggcgc aggtgcactc agggcgtatc 43680
caaatccact tttgctattt taacgacgga aaaacggtcc atgcaccagg gtgcattttt 43740
ggaatgggtt gtccctattc tcttaatgag taatgggcat aacattcaat taaccaatca 43800
gagtgtcatc tcccattccc tgtgtgagat gcgctcacgc atttgcgccc attggcatgc 43860
tggtctaaaa aaaagaggtg tgttcaggtg cattgctatt ttgaggagct gaaaatagac 43920
tgcgccatag accaactcaa acctggtcta aagtctaaag tcaatgacga aatatttttt 43980
tgtcatttaa agagcacgtt ggtagaaaat gcgcctctgg gcaggtccac agtgcgtgtt 44040
cactttgctt attatacaca gggatgcaca tcacacaaac atccaaatat ataaaaaaaa 44100
aggattacag tgtaaaagaa tattattgtg taggctacaa aaatataaaa atgtcattat 44160
ggatagtcat tgcgtgtatt agaattatac ttatttgcaa ttacagaaca attacgctgt 44220
gcatttagat cgttaaaata gggccccaag gctcctgaaa aagtggacct gaaaagtgtt 44280
ctttaaaacc tggactataa ttctaagtgc ttgcattacc acacttaaaa caaaaaaaca 44340
atgtaaacca gccaaatgac ctcattaaat aacgtggctg gctcaaatta ttgtcatctt 44400
taaatccaat agtagggctg tgtggtccat aaatacagag atttccggag gtctggaagt 44460
gtccagctct gcctggctgg tgatcacact ttgatagacc cgtcagcttg tgtttgctgt 44520
gtgggccttt tacaatcaca gtaattattc atgacaggcg ctgctatggg gctctgatgc 44580
attcaatcca atcagcagca caaggacccc cgaaatctga ccatgtagat aaacaaccaa 44640
agagagaaat agtggggaaa cgactgaaat aaaactgtgc tctaataaac aacattctta 44700
cattcttaca ttcttacgca aaagctatgg tgtgttttca catacactat agctggattg 44760
aaaacaggca tgtggtgaga gtgtgtgttt atgtctgttt gtgtaatgtg ttgtgttttg 44820
tttatgaaag caacagagcg tgaaatgata aatccaatgt gactgtgtca tgaacacatt 44880
gtctgcaaac cctcccacct ttgtgttggc atttgtgtgt ctgtgtgtgc gagtttttgg 44940
ttgtgacaca ttttattgtt atcttctctc ccaggcagtg ccagaggatg agcggttggc 45000
catcgccatc attttagtca tgtgggtctc agcactggcc tcctctctta tagacaacat 45060
tcccttcact gccgctatgg taaggaacac acatactcct tcagacattt tttgcacaca 45120
aacacaaaga tatggtgaaa caaaactagc tctaaatctc cttctagttt gtctgacatc 45180
tttgtacaat ggcctttttt agtaatttga cttgaaagaa ggcctttatt tgataaaaac 45240
ctactgtttt ctatatttta aaatgtaatt tattcctcta atatgctgat tttctgctca 45300
agaaacactt cctttgttta tcaattttgc aaatagttgt gtggctgaat atttatgtgg 45360
atactatgat acattgtttt tatgatgcaa tacaaattat attcaattaa attattaatt 45420
gacaattgtt tttttttttt gtaaaaataa attggcatta tatattatat acattatata 45480
tatattatta gatactgaaa tcgctcacca ttttgttcag atttaatcat attttttatg 45540
ttccctgcaa taggcctata ggcaaagtct tttatacaac aattctctga acaaggaagt 45600
tatgtagagc gtaatatgca gacacttgat cattatcaca aaataagaca agattatcag 45660
gcctctgatg tgagccagga gggtcttgca tgattctgaa gcaatttatg taatgataat 45720
gactggagtc tcttaacttg agggactgtc atatcttgcc tatagggagc ctgaatcacc 45780
gccagatttt acagttcttt caatttaacc cctgcaagca aaatcaaacg ggaaatgtct 45840
catcgctatt gtaacgatat ttatccaacg tagaagacta gtgatgtttt gtgattataa 45900
ataaatgaga aatatgcttt ttcaaacagt tttagaatgg catgtctcac tggaggtcac 45960
tgccgtcact gcttgacatg ttgtgttcac taccccaagc tctgttgata ggtgaataca 46020
gtgcatctta tcctctatag tcaaccgaaa catgtgagaa tcagtagtga gtgatgatgt 46080
gctatcagag taaggcatga atcatgtgca tcataaagga gcacgtgctg tgagctgata 46140
tgatgaacat ggcaccagac agacagagct gtgctgccac tcactcactg ccagatgagc 46200
agaagggagg aacaaaaggc agatgaagag acaagtccac ttagaatttc aaaagacttt 46260
tcattttctt ctcctccagc gttttccacc ggtttgattt gatctgtcca ttttgcgtaa 46320
ttactttcac ttcttttctc accttgtgtt tagtaaggat gggcagaact acatcagttg 46380
ttgggttagt caactagtta ggcaaggttt ttaggttgta aggagcaact tgctgaacac 46440
tagtccagta gttaaactga cgatgattat atagatattt attaggacgt ttttacataa 46500
agatctcact gtgtttgact tatcagttgc tggatgacat gttagccact gggacctgcg 46560
actcttgtcc ttttttgtct tattcttgct cactgtctgt ctctttcatt cactttgtca 46620
aaaaaggaga gataaacagg gtgaaatgta cttgagctcg gcatatacct gctggtggta 46680
atggactgca ttgatttcgc tggtcccatc actgtataaa tgcagaaaaa gacttctcag 46740
taagtgctct ctcacaatct gaagctggaa taataaagac catgcagtta aacacacact 46800
tcattaatgc agagcacaga atgggcctgt ttctgactgt aacaacaaca aaaaattgca 46860
tgtattgagt tatttgaact tattttaact ccccacacga cttcataact agcttaacca 46920
tcatcaacta ccagcttcat tggaaaggtc atttaactaa cctgaatata cttgcatgga 46980
aattcctact ggtctgagca gcaaatttct gtggttagac atttaatagc ttgaagtatt 47040
gactctaaat cacaccatgc ataaggcaat tttaaattgg cttgccatgt ttcggtccat 47100
atatcaggca cagtgtgttc ggtttgagta ttctatatat tttcgaacgt cacacaatca 47160
ctgacatcca catggagcac tgaatatctg atctgaatat caatacatct gtctagaagc 47220
tgtttacttc ggtccctggt ctcatctgta agggattata tatgacatat acatggctgc 47280
agtcatggcc ctgctcacca tgattgtcga tctccttttg tttccatggt tatgtgttgg 47340
gtgacttgcc agtgattgtt ctgtaattgc aataagtaaa ctggatcaaa gtgcttgtgg 47400
gatttaatga aagtgatcat ataacatgac cattattgag cgttcttaac ctggataacc 47460
taaggttctg tctttgtggt aaatctttaa accacaattg atgtttaata agtggggatc 47520
ctgaaattaa tctgcaagaa atctaaaaaa taaataaaat aaatgcatgg taagaaccag 47580
tatatctaaa tctgactgac agcaacgaaa ttatttaatt taattaaaat gtattttagt 47640
cctgtgaata gaattttcag cagccattat cctatcttca ttgtcatgtg gtacaaacct 47700
ttgctagagt tctgatgtct tatttatgct tgtgttcagt caacacaagc aagttttaaa 47760
aacacagcat gtgataagcg tgaaatatgg tacttcagct caagtcgtat ggacttcatt 47820
tatgatgttt tatggtgccc tttttgagct tgactgtata catcaccatc cattttactt 47880
gaatgaatac ctaaagccct cctgaagatc tctttttgtt gttgttttgt ttcacagaag 47940
aaagaaacaa agaaacgtcc attcaaacca taagtttaac atgctgatgt ggtgcccaga 48000
aaacatttct tattattacc tccattattt attatcatca atgctaaaaa tagttgtgtt 48060
gcttaataac ttgaagaaac tgtaaaaact tcttttgata aataactgca tttatttaaa 48120
atggacatta ttttgaacag tgttaaagtc tttactgtca cttttcgatc aattaaatgc 48180
atgcttacct gagtcaaagt gttaatttct ttcaaaaatc taactatcga atggtagtgc 48240
atatatcaat atatgataaa tatatttcca attattagga tatttgttag ttaagaatct 48300
attaattaag tgtgatatag ttcgtttttg ctaaataaat cctttcaagg tgaccatggc 48360
tgtgatgact ttgtggttaa aaacacggtt gctatagatt atcccctcaa tatagtcctt 48420
aattctacac ctacataaaa gatcaaatgt ccccatatat tatttatcac agagtagctg 48480
ttcatgtgta gacaacatga tgaaagttta atataataca tatactaata tttatgatta 48540
cggagttatg ataacagaga gcatgtgtga tatctgtaaa aatgtttcca tgccacctgt 48600
gtcaagttag gattttccac acagatttaa aatgtgctac tggcaaatgt agtagaaaat 48660
gtaatcacag ttgtgctgtt taatttattc aagttgattg cagctgaagc cgctgttagc 48720
tgggaggcca gcgtgtagca ggcaagcggc tacacacaga aatctttgag gcagaagaca 48780
ttttctgcaa atatgcaatc tttaaattat gctacactgg tgggaagatc gaatgcttat 48840
gtgccttatg aaatggatgc atgcatattt gttgttgtcg ccacagggat ccattccctg 48900
cttctcacca ttatattgtc ttgctaagca ctgatggcta tagccattgt ggagtgtttt 48960
tatcctgttt atatccatgt agatttcatg cctgggccaa tgcagtgatg cttggatcat 49020
acatgctgtt tcatgagatt ttcatttgct gtttattcaa gctctgtgtt tgtgcaaaaa 49080
gagagaaata tggaaaataa atctaatggc atcaactatt gattttcttg ttcttgactt 49140
gtggagcagt agaatatgac tcaatttgct aataggttgg gcggctgtca ggatttgtga 49200
atattacatt ctctgtgacc ctgacatcca caattgcctg tgagaattat gatcaaggca 49260
ttttgccctc cctgtctgtc tgtatctctt cctacctacc ttatctacct atctatcatc 49320
ttatatacac actacgtata atatatttat ctgatgtttt tttttcccta cagattcctg 49380
tgcttattaa ccttagtcaa gatcctgatg tcaacctacc aatcaaacct ctcatttttg 49440
cattggcaat gggagcttgc cttgggggtc agtaaaattt ttgtctctct cttatattat 49500
tcagtgtaag tgttttttgt ttttctttaa acaaacatgc cattacagca cacttggttc 49560
aagtggattg atgaactgca gtgaaaacta tgccttttaa aatacataat ttgtagcatt 49620
tcatttgcat tgcaaaccac ctcctataga agaaaataag taattgcttt gcataaatgt 49680
atctgtgtaa tgtaatatat aattagcaat tctaactagt gattcaaaaa ggtctctttt 49740
tattacattt tgacaaacat aataagctgt agtttttcag tgccactaac ttcttcctca 49800
ctggctctga aagcaccact gtgcttacaa ggccatctga aaatgcctca ttgcctgttt 49860
ggttctaagg acatggagag agatgtggca gactttctgc caaatcaaag gagatgtgtt 49920
agctctagta ttgatccatg gaatgctaag gcaggcttat ggttttgttg tcacgctgac 49980
acctttgaag atgtgaacat ttcatatgaa gaccattctt caacaaggcc aaacaacacg 50040
cttcaagaaa tactgtatgt atcttagtaa aagacaaatt gatgggtgta aactgcattt 50100
agagttttaa attgtttaaa tttataatat atttagccat taaataaaaa atgtaatgtt 50160
gacacatcat ttgctttctt ttttaatgtc tctctatata attactgtac aattatgcaa 50220
ttgatatgca atgatccttt caaactctag attttcaaaa ttaaaaaaat acatattttg 50280
atatttttat gatggaattc cattgtttat gacaaattta atcaaagaca aaatataaaa 50340
ggcatttgaa aatagtaaaa atgatgcagg aatggcaaat gacatctgac aacagtttaa 50400
aacagttcaa ttcctaagat aagggaacaa gcgttgtgtt aacacactat ggggaaagtc 50460
ctgtttactc tgatactgaa gcctgatttg ataaactttg tgtagctgca tgaaccaacc 50520
gccaaaagct tggagctgac tgctatatcc tgtcagctct gagtgccatt ttgtcagaat 50580
ctttcgacta aggcaacagt catcgactag catgcagcct tatagcatgg ccagcctaca 50640
caaggcttat ttccttatct caaggatctg atattatgta agtaacctga gcactccctt 50700
tcaaaaaggc tctcccgttg cattaacact atatgaggaa cgcaccaatc atgctgtgct 50760
ataagtatgt gcagaactga agcccaaact caagacatta agtactgact gacagtcctt 50820
gcaggtcacc cactcgcttg accgataata aaggcagagg tgacaggggc cacaagttgg 50880
ctgattgaag cagtttgaag ggagggcaca atggggccct aaggactata gataagtccc 50940
aagtcagaac agtatgaggg cgaggcggat ctccaaagct cccctcagaa actaaatgat 51000
caggtcgttt ctggcaattg acctgtcatc tatgagagag agatttgcca taataactgc 51060
cacatacact ttgacccctt gtccaaaagc tcttgtagaa aagtaatcat gtaaggcatg 51120
tcgcaggagg atgggtcctt attctgtgct tcacacccgt cagaaaagac taccatttaa 51180
agctgcacta agtagacttt gccaaattat gttgatattt gaaagcacca aaacaaacat 51240
gcccataccc tgataggact tcgcccctat tttgataact ccgcccaacc cgtacataca 51300
catcccttaa agcgatgatg gcaaaatctg ctatgcatgc cagccaagat tattcaagca 51360
aaagtcaaca cagattagtt gtgtgaaaca agcaaaataa atgtaactca cctatcaaga 51420
agaaacaaag caaccttgaa taccaattca aaggctttcc cgctccttga gttctctcca 51480
ccacttgaaa gctgcttcaa tatttatgca tgccctaaat tttgccagat cataatccta 51540
ctttttaata ttttatttta cttctaatct gccatctatt gctacctata tttgatctgc 51600
taatatttgt cctgtgcact cactgagcgt tctcttctcc ctatcattac tagacactcc 51660
ccttactcct gattggcaga aagtgtgttt ttggacttgg tcagacactg tggtcaaaag 51720
tgtttttcaa atattgctta gtgcaccttt aagggcatag agatgtctta tagatggagc 51780
tgtagcatcc aaaatgttac ttacaatgtt agttacactc acagagaact gcaaagactc 51840
caatatatat atatatatat atatatatat attatatgaa atattcacta ggcatatata 51900
tatcctatat ttcatatata atataatgaa tgcctaagtt tatacaggct atcaaagtta 51960
tgcaagataa tcattctttt ttctttttct ctttctattc aaaaggaaat gggacactga 52020
ttggagcatc tgcaaatgtg gtgtgtgctg gaattgctga acagcatggc tatggatttt 52080
ccttcatgga gttcttcagg tatttgtgtt gggcacaatt ctttttattt ttttccccac 52140
agcttttatt acaaaataga gattcttttg ggaccagctg tgaagttgag ctcaaattcc 52200
acacacattt tctgctgttt tggtgtcctt tctgtaaaaa catttaaaga gacatgttta 52260
aactcatgcc attattttaa tgcatttttg gtaacactac gataaggtca cttttgttaa 52320
cattagttaa actacattac atacagtaac atgaactaac aatgaaagaa taataaaaat 52380
ttattaatct ttgttcattt aacatttact actatgctat catgaatgaa tcaatgaaca 52440
gttatatttt tattaattaa cttaaagtct aataaatact gtaacacata aaatgctcat 52500
tgttagtgct cactgataat tgttcatttt gtagtatttt tactaccgtt aagtaaaggg 52560
accttatttt aaagtgaatt tttaatgcta gtctataatt tttttttata gtctattata 52620
tccctctatg atcggttact tgataatttg gttaggtggt ctcttactaa gtgagcagtt 52680
cttagccaga ataagctgtg ataagcacca gacactttca gtgatttttt ttttcattct 52740
agatcaaagc tagtattgct aacagcaaac gtacccaaga ttgccctggt gcaagagtca 52800
gtccctagct ttatgtccag atgtttatag ccgttcatga actctcactc ttcagggaaa 52860
tctgtggcca gtggtatctt aagtgacact tatgccatgt ttccaccgaa attccctgga 52920
atcaaatgta ccagaaactt ttttccccag gaactatttt tcccccagac ctgttgcttt 52980
ctgcatttcc actgcagtct aaagtaccgt gaagtttagg caaatagtct agtaacatag 53040
atctgcccgt gtttctcaat aaaaagtacg cacatttcgg cggtggaaat gcggcttcag 53100
gtagtctgtt tcagggtata ctctgataca ctttttagca atctgcttct tcctgtcatg 53160
ttctcctttc tcttcacatt ataaaatata ccatttaaag gtggatcaac attgcaatca 53220
aaaagataac tgcttaacca gcccttacaa taaaaatgcc acacaactca tgacattttt 53280
ggttgtaaac atatttgtct ttgtatgctc cttgaagtca atgtaaattg atcatgtaca 53340
tcgtgtccca aaaatatccc taagcgtgtc tctcttttta agacatgaca gacctagttt 53400
tagagagact cttaaaacag cttgatttca agcactctct agtgtatcaa caaatacatc 53460
tgaatgtgga aaatgagctg ctcactgatt acctcttggt gagaggcttg cagagatatt 53520
cactgtctct tttgattcgg ttctccttgc ttgtcaccac ctgctcgatg gaagtgcttt 53580
ccatgcaaat acagatgcat gcagatatct ggctttctcc cagttggtgg gtgttggtgg 53640
tcaatggtga aaaagaggaa gctgaatgca catctgattg gactgtgaaa tgatctcagt 53700
gggagacagt gaggtctttc aatctcagta tataaaatca gaaaaggaag ttcagacatg 53760
cctagcacag agccagacat gaaggcactt cacactttca ccattacctt tgaaattttg 53820
tgactttgga tttacttaaa tactactgta ctttgcccaa ctccctgtac tatataaaat 53880
ggctcattct ccattaatta ttattgtcaa ttttattatc ttattaatgt aatttaaatt 53940
gaatgtaatt aaaatatatt ttgggagctt ttcttagcaa atatcgattt ctgtaaataa 54000
ttgcaattaa ttctgttaat taattggcat attctgtatt taatcagatt attgttaggt 54060
cattttttat attttttgtt atgtttatat atatagtact gtgtaaaata tataaacatg 54120
atttatttta tcgtaatact ttacgataag gttacattta ttaaattttt atttataata 54180
tatttcagat taaacactta gggttcaatg gatatcaatt acatatcacg aatgaacaat 54240
tatcaataat tttagggcat ttttaaaatg ataagtttaa tgaattaaca ttagtcactg 54300
taaaatgaac cagcatgact taaataagga attatttaac gacaggccat tgaaaataat 54360
gtatacctga atgcataccc atataattca acgtactgga gtcaattatt ctggttatac 54420
tacgcttacc acacctcaaa tattgttcag atgttgtatt taaagacagt aatcaggttt 54480
ttgtccttaa aaagctcttg tgagtaggat taatttctta ggcatgtcat ccaacatctc 54540
cgttgttaat tccaagacat aatttaaatc ctagcaacgg aggcttgagc cattgatagt 54600
agactaataa tgcagttaat aattagacag agagagatta agcttgtgtg aattaactga 54660
gtttgtgcgt ctctcaaaag tgatcggcag caccgtttct accaatagcg aagctatagt 54720
ttcatcatct tcaagaaaag ggccgttatt agtgggaatc gacgtagctt ttaagctgct 54780
aaactatttt cctgcttaaa tcgtcagagc aatgccaaaa acacgtttct gtgcgtgtgt 54840
gttaacgtgt atccaagtgt gtgtctgtac tgtatgagtg tgcgtctgta tgggggcgat 54900
aatgggagaa ataaagtatg ttttccgtac ataataaaac ataactgtgg caaaaacatg 54960
gaataatttg tcatttttat ctagtttatt gtatttattt actaggccag tgtcgttgtg 55020
ggttttggtt attttgctgt agttagctgt aaggaccttt gaaataacga agtgatctgg 55080
acatgtaatg tggttctaat tgcacacctt taggttgttt gtcagccaat cagattcaag 55140
cattcaatgt agtataatat gaattaatat attatataaa atattatata aaattaattg 55200
tattgttagt tcatgatgcc taataataac tgaagcagga actaatacat tttactttat 55260
tgtaaagtat tacaaaacat aataatattt aaataaaaca aatataaaaa tatgtaaata 55320
aataaacaat ataaatgaaa taataaaatc taatttgttt atataatact gtatatagag 55380
tatattctat aaatgtaatt aatattttaa tatttttcca tgacctaaca atccatcttc 55440
attgacaagc agtcactaac tattttgtag ttcctttact tgtctgtcta agtggccatg 55500
gcacctttaa accctgaaac aggagaaatc gaatatcatt agactgagtc caagtcccct 55560
cggctcaaca cagcgaagga acaggagctc agtctaaact gcacatcaga cagggagata 55620
aggcacatca attcaggcta aagttgggag tgaatccaat ccgtcctagt gttagcaaga 55680
accacatcct gcctcactct tcacttttag ctgaacggct gccacttgct ctcgattctg 55740
tttcagtaat gaagtacctc tgctaagcca aagacctgct cactgtgtgc actcatgaaa 55800
tgtattctca gattccctcc ttcctcgttc tagggcccat aggactgtcc agaggcaggt 55860
agagcagctg ggtgactctc ggctgagcca aatggggatg ggctggtggc agcggggtgg 55920
gtgagggagg aagcaatcgc ctgtgggatt taattttttt ggcagtgcta ggaaaacaaa 55980
cagggtggca gcagatgttt tagtaaatgg tcattcatca ttaacctccc tcctgcttga 56040
tgctcagaga gaattcaagt cattcttctc aaccgctgaa tattatctga accacttcta 56100
tacctcttca gatagagtcc cagaagtatt taaattgcaa tgtaatcctg aacttgagaa 56160
gattcacttt ttgtatttgg ggcctgattt gtgtgccttg tgacactgtt cctcacctga 56220
tttgtaaaat aacaagatca cttgtgtggc tgactcattt attttatcca caatctaagc 56280
acggtatcta aaatttctgc tctaaaagtc ttggtctgat ctgttcaact gtaagtgaca 56340
ggaagtcttg cattggtgtc cagattttat taaactgtgc atcacactct tttcctgtca 56400
atctcatgcc cttttccgct aaccctagcc tatcccaact gaggcgatat tggctcgata 56460
tgacttgctt agctttgcag ccaagcccct tgacctccat atatagtttt tcttagaaaa 56520
ccattgctga ccattttcgg tgtaaggagg ttagtctgaa tgactaaggc tttggggaca 56580
tgctcttaaa acggagcatg tttgccatac catggcaagt tgcctatatt gagcacttgt 56640
tttttctctc tccaacatcc atcttctgct ggcatttttt gtctctggcc aagccctctg 56700
agtgaactgc agaattaatg aagtgacata cggcaatgtt tcctgaccag ctgtaaaact 56760
ttaatgatgc agagcttgta aaattcattg tctacacagt tacctcacat tattgttggg 56820
ctatatgtct gactcttgac atctttacat ataagtgtca cctgagcagt tccaaaatag 56880
agaaatgaac tgtaacagtt tgattgtata atttgtatat ttgcttgaat tttttttggt 56940
cagcaagaga atctctaata attttaatgg aggtgttttt attttacact aatgaaaagt 57000
tagaatttag taaaacttca gtaagcattt taactagctt ctctggtgca gaaaataaat 57060
ctaacataga ttaaatgatt agcggactta taactactta ttaaaactgt attgttttat 57120
ttcataccac aatacctcga gagcctaggt ttgtaaataa tataacatca cttaacaaaa 57180
tataacatca cttaacataa tataatataa tataatataa aatttacaca cttcagcttt 57240
agtattattt ttatttttat tagcagtagt agtattctat ttttccttgc attctcttgt 57300
taggacctat atgtagtatt tcatttaaac ttttttcttg ctttctttct ttcttgcttg 57360
ctttttcttt ttttctctct cttggcaaac ctgtgtgata aaaatggaca aaacaagaca 57420
agtattgcat tgcatatgat catatgctaa aagacactgt ctatgatcat atctcaagag 57480
atgttcttca tacaaaaaga atgcaatatt aggccacttt ggctgtggct gtaacactgc 57540
tttgatttta ctgaaagatt cagtttcacc aagatagtac agaaattctc aactgtttca 57600
agtaccattt gtaatcttgg acttagagat tataattgta caattttcct gtaattgttg 57660
agaactgagc cacttgatga ttcttttaca gagtcactca cactataacc acttttttaa 57720
cctttatgcg atagctttta gacgtaataa tgatcgctgc ccattcagac ctttaatgat 57780
caaagtttca tgctgttacc aagctgcaat aagatccctt ctccatgcca aattatatca 57840
ccctcccatt tgtttgaagt gttgtgagag tcttggcctc ggaggaatgc ttgtttgaga 57900
ttggactaca tgctaatgga tttcctcttt aacattcatt taggaacaaa gagaaaaggc 57960
ttttagaagt ttatcctgat cctgatgttt cagtcactgt tttttttttt ttttttaagg 58020
tgctgtactt cttaaggctg tcaatctcaa gtctcatgtg attttgtgtg tgtgtgtttt 58080
agggcaagtc tctgaaaaaa taattaggag cccattattg cagatgggga ggacctagat 58140
tgatactatt tatagcctct gtagtgtcac attggaagca tgatggatgc tgtcaggctt 58200
ctgttattaa gggagggagt aagtggcaca cctgggtata caggtttaca gcaactgaag 58260
attagtgttt tatatatata tatatatata tatatatata tatatatata tatatatata 58320
tatagagaga gagagagaga gagagagaga gagagagaga gagagagaga gagagatatg 58380
caggctttga gaagaacact catcaatgtg tgtactgtgt cccctttttt actgtcaaag 58440
gaaataacat agaattatta ttaaaccaaa atgatttggt tagtttaatt gttgattagt 58500
tttaatacta atatgctatt aaactaatat gctattaaca aactaggcat ctatattctt 58560
taagtattgt gtagtgtata cagctcagtt atacccctca gctggtctac ctccacagat 58620
ttctaaaagt tcttacattt ttaaagatga tatttcagag agctccatta catttttctt 58680
ttctcctgtc atttctaatg agtctttatt ctgctaccac tcttatagcg atggaaaatg 58740
caggcctaaa tagcatacac gacaccaaca aaacttttca aatcatttcc agttgtattt 58800
ctcatcattg tggtcagttt tggtgcaaat gcaaaattaa tttatgaaaa gaccacactc 58860
ccagatataa agccagagtg aactgtgatt tcagaagctc catttcattg cttaaaatca 58920
ttaataataa ttttttggaa catgtaattt ccttacctgt aagtaaaagg ataattcttt 58980
aatctttttg gatttaatga tagatttttt gcaagaaata gaggtgtgtg gtctgacctc 59040
aaaacagaga caacaacaca gcgagacaaa atgaatctta cagacactag taattcaatt 59100
caattcaagt caagtttatt tgtatagcgc tttttacaat gcaactcgtt acaaagccac 59160
tttacagaat attatgtttc tacaatattt agtagtacct tatataagtg gtgaatgtca 59220
gtttgtgcac gtatgacagg atttgtagaa aaattaatac aagacgtagt cagccagatg 59280
atgaacatta ttaatattat aataataatt attattatat gatgcagtca cacttgtagc 59340
aatattagtt gtaatgtttg ttttctccta atgtttcctt ttcttcttct tcttcttctt 59400
tttttttttt ttgaatatcg gaattatgtt tgatatatca taaaacaagt aactaatcaa 59460
ttactgaatt caactagtta atctagattt gtttcaaaat tcttatgatt tgtgagtaaa 59520
aaaaacaaac aaacaaacaa aaaaaaaaaa aaaaaaaata tatatatata tatatatata 59580
tatatatata tatatatata tatatataga taatcttata taatcaaata atatatctgt 59640
ttaactgttt taaaagcagg aacatgtttt atgtaaacgg accctaagaa atgtgtccat 59700
ttggtgtcag atatacctaa aaccagttta attagttaat cagtgcttct taatattaat 59760
aagatatata aacaaatcat tgagaaattt caatatgtag tcttacacat ccctattttt 59820
cattcccaca tggtctcttt ccctcatgta ttggtatgaa tatacttata tctctgtgct 59880
tgagaggaga atagcagcat gtgtgtgtgt aaccatgggc aatcgttgtc ctattgtaca 59940
aacaaaccca gagcttggat cacattgtta ttcccagtac catgccaagc cactttggcc 60000
ttcaaaatcc atcatgtgcc ccataacact ggcatgtaag ataatggtgg atgtccaaat 60060
gacaaaccat ctggtgtgcc ttttgaaaag tacagactga tgacaatgat ggcatttata 60120
gtaatgtctg aaatatcagg cttaatcaac actgacctta atttccactc actaccgtgt 60180
ctttgtctga ctttgagaaa gtcatttcct tccctatttt taatggtttt cccttttttt 60240
tcctctccag ttaaaatgtt tcagaaaatt gccaatctga cgcattctga gccgcatgag 60300
attaggaaat gttgtgtaca tcagcaatct tgtagtgaga gtgggtgaga ttgtggcaga 60360
tagcttttcc ttatttcatc gcatgttgga gatgttgagg gtttttaaca caaatgtgcc 60420
acatagtcga tagccttgag caaggaaagc tggacaaaat ggataaacta atcataattt 60480
ttttcctcaa ctcaaaacag atttttcccc aaggtcatgc atatgggcag tggtggaaag 60540
agtactgaaa atttgtactt aaagctgcag tagggaactt ttgaggctct agcggttaat 60600
aaacagaact gcttgcgtct tgcggaagaa catcgtagcc ggaactactt ctctctgttt 60660
atgtctatga agaatcacaa aggtacaggg ttactccgcc gcggtacccc cgaaacaatc 60720
taaaatagtg cgaatataaa cacttattat aggtgtaccc tagtgattca ggacaagcta 60780
aaaacacggt ttggaaaatg gattcatggt gtactcgctt attatgttca tttttctaca 60840
ttttgaacac aaacaaagtt tgtgcagctc tgattggttg ctttttaccg ggagcggatg 60900
actttctgca aatggcaata ggaccactgg gaggagccag aggagcttga ttttttttca 60960
cagattatct gtctcatatt ctactgtcag gacataatga caggtgtaac aaatatgtaa 61020
aaaatatatt tttacaaaag ttacctactg cagctttaag tacaagtact gttacattga 61080
ttaaataata ctcaattaca agtaaaaact atcaaaccag tacttaagta aaagtaaaaa 61140
gtacttagtt actactagtt actttttagc tggtgatatt taattaccaa aaaatattca 61200
tatcaaagat ctatgtaaat ggataatagc aactttgaac aaaacccaat tttatcttat 61260
tgacaaagta tgttaattag tggtcatgat acagggattt ctaacttcaa taccttggtt 61320
ggataggagt ggttaaaggg gtcctattat gctcttttac aataacttga atttgttttg 61380
gggctgtact tgaacatgct ctcatgcttg gtaattttcc acataattta cattattaca 61440
atacctttct ccccagcttg gcacaaatgt ctcgattagt tccaggtttt atgaagacct 61500
gccttccgaa aaacaaaatg tgttgtgatt ggttagctgt cccagtgtgt tgtgattggt 61560
gaacatagat aaggatggca tcaatattgc catatcaatt tgatattgtt ttggaaaaca 61620
acgctgtagt ccagacaagc tgtttattgt agttcttgaa aagggattta aaaaaaaaat 61680
ctccctttgg agtggacttt gagatgtgta actttgtaga tctttgttat gcccaaacat 61740
acacactaca caccgactaa aattcaaaaa gagaaaaagc ataatagacc ccatcaagaa 61800
tatctgtttg ttacgtctga catcatcctt cactacttct gggacataat gctctgtcag 61860
acgccccttc agaaaacaac aacctgattc agctaaaata ttagtgagca cagagactgt 61920
agaatgcaca gtaaattacg cttagattaa ataggaaata ttaatgaaat agtgttaata 61980
aatggctgct gagatagtat tctcaagtga aatgagtaga ggcttggaca tggaaatagc 62040
agtcctaaca tcatggctta acaagaggat tctcccaagc catcaaactg gattcatcag 62100
agcaagaaca ccataccaaa gccggaagcg atggcagact attttgttcc cagtgtattg 62160
acttgcatgg ttcaactatt tgctacaaga ctagtactgt gcactaaaaa agctggtagg 62220
gttattttta atttcatgat gtacaaacat tttcaacacc attggcaaaa cctccacata 62280
ctgtatactg ccatatacct gtagatatat ttttttgtcc atccatttgt ataagttagg 62340
cctagttttc tgcgattaca tgacagcgtt ctcatgttgc aataaagcgc ttgtcatatt 62400
tgtacaggaa ttattacaat tatgccgaat acctgcaatc ccgtgcagac attcagactg 62460
ttattgacag gaggctgatg attgtcaaac caactcggag agaagagaga gagagaaacg 62520
cagattgtat tggtgtatat tgggtagata ctgtggaaaa tgaataatgg aaccgtgtca 62580
gatatttcag tatcggtatc aaaatataga tatttatgat aacactacca tgtagtttgt 62640
ttctccaagc tctgagtcca taaatgacgc tgagctccat ctctgtctga tcagctcttc 62700
acccgctgca gcggcgctgt tctcggttca gacatcagcg ttttgattcg gtccgtttac 62760
gatctgatat ttttattggt tactgaagta ctgtcaaaaa tttaatatca attcaaattg 62820
tgggcgtact ccgtaacgaa ctataattaa aagtaacgaa gcagattatt ttgcttaatt 62880
tgtacttaag taccagtaaa agtacagctt taaaatatac tcaaaaaagt acaagtaccc 62940
gaaaaaaaac tacttaatta cagtaatgtg agtagttgta tttcgttacc tccaaccact 63000
gcatatgggt gttgtggttt accagtaaag atctcagctt ataattcaaa ggttttaact 63060
ttgaacacca ttagcatgct gtgggttagc tgttagacaa tttcatcttg aaatgtattt 63120
ttgtacatgt tatgcattac tagaaattca tataaaatca agctgattaa tcagggaacc 63180
ctattggctc acgttgtttt ttgagcactt cactgttatg gttttaatca tgtatatagg 63240
tgctggtaaa aatggtaaaa tacctgtgct tataattgaa accttgtcga tttaaaacca 63300
agaaggacac aattaatgag ctgccatcat tttgcccttg agcaaggtat ttaaactcag 63360
gacactgatt gcaaccgtaa tgtaaaaaaa aggtaattgg gtcactttag ataaaacatc 63420
tgctaaatga ataaatgtga atgtcaggca ttgaatagct tgaaagactg cctcaatacg 63480
catgttggag tcatctttgt ccctctaaac gatttgtatc acctttgcaa gacttttagt 63540
cacattactc ttctttccat taggcctcta aagttgtaaa agcatgactt tgatttttag 63600
gatggtttat gcagtactta gtgccattta atgtgctatt tattcatcca gtttaacaaa 63660
ccacattctc acactctcga atccttggtt tcactgcaca tcgatttgtc cacttcacta 63720
cttttgaatc agtctcctgg ctgcttcatt gacatcactc aaattgtgta ttagccagct 63780
gacctgccct cacacccatg gcatgtgcac ctgctttgat gtatgtctca caaatgcctc 63840
cttatacaaa taatacacac ctgttccttc tgcagtccag cacttagcct ccccacctgt 63900
cttctggaaa ctgaacacct ttttttttcc tggaccagct gtgatctttg ccatacttac 63960
atgaataggc ctttaaatat gtgctttcca ataatctaat tttagagaat gttagaaaga 64020
gataaagtag aagacaggaa gtgctggagg acactattcc atttgggatt gtattacgct 64080
attaccctca tgtctcattt tctgtctagt tttgtgtgct ttgaaagccc ctttctatgg 64140
acactttcac tgattcctta tttaaaatcc ttttgtgtgt gtgtatgtgt gttgaaggga 64200
gaaaataatt atgtacaatt ctggtttaaa ttcagttttg ctttacatgt atgcatttcg 64260
cagacatttt ctaaacaaaa cattaaggag tatgttttat catttcatga taattgaaca 64320
catgatctgg gagtcgctcg cagcatgata tatatattat taatattttt ggaaggtata 64380
gttaaccaaa agggaacatt tgtgaaagtg ttcttaaaaa aaaaaaaaaa aaaaaagtga 64440
aaagtttaga aatgtctttc ctgattctgt caagacaact ttttcactgg agaaaacaat 64500
ttcatggata gatttttttt tcaaacaatt tatttaattt aaaaacgttt taataataat 64560
aaatgtatta aaaacacaca gcttttcgat tcacaaacta ttaattggac tgttttggac 64620
attctgatgg cacccattca ctgcaaagga ttcaatggtg aacaagtcat gtaatgctaa 64680
attcatccaa atctgttctg ataaagaaac tcatctgcat cttggatggc ctaagtttta 64740
ttcctttaag caacacctaa acttagcact ttttttgatg agttgtttgg tttaagatag 64800
tgatttgcaa cattttaagg aaaacttgtt tctccttctc tggctcttct ctggattttt 64860
tgctcttttt atcatccact tgctttccat catcctctca atcagtggcc actttctctt 64920
ctgagcttgt tgatttcttt atgccccaaa tgctctgtat ttacccatcc actcagtcag 64980
tatccaccaa gctactgaag gtatgcactc ggtataaatg gatgtccaga gctttcaacc 65040
tttcaagtgc tttgtcctct cagcagctct ttcattcatt cattcattac agaattcatt 65100
cattcattca ttaccctttt tacaggactt ttttcccttt ccctttcaac aacaagatct 65160
gaaatttatg agctatcaga gaagtaaaca gaacagaaat gattaaaact gcaatgtgga 65220
tttttagtgt tctgtaaaaa gattattttc tggggcaata ataaaacaga gtaaatgttt 65280
tcatagactc aactcatgtg ctattattat actatagact ttagtcaggg actaagaatg 65340
aaaatgcggc aaaatgaggc tttaagtgat agaagtatga ttaatggatt gtaccatgtt 65400
taataatata ttatttaata atatattatt atattattat tgtttagata aaacttccaa 65460
tagacaaaaa aaaaagttgt gagttttggc aattacatga tctgtgacat ttatacaatg 65520
gatgttattg taaggactgt aaggttatcc ctcatagcct ggtttcataa aaatcaacgt 65580
gacttctaac ctgactaagg tctagaaaat agtataatga caattatata gaatcctcat 65640
atgggtcttt attcttacaa atctgttaaa tggacagtac taccaattag tccacatgac 65700
ctgtgtataa tattttaaat taattaaatt ctttatttgc tgataatcct aatcttcccc 65760
tccggtgagc tgttaaatgg agaactgctg gaaccagata atttaatcaa tgaggaaagt 65820
ctagttcatg agcaaatcat ttcgatacaa gaacattccg attcgtgaag aaaatgatga 65880
gcctgatttg tcaactgaat catcttatta ctttaaaaga attcaattca tttcctgatt 65940
tgtttcaata acccagtcac agcaacattc gaattaatgg ctcactaaag ctatcatgtg 66000
gcttaaaaag acatgaacta ttgcacaaat gtgctataga ccttagttcc ctccccactt 66060
catatcaaac attttgtaaa gtttttttaa acttatttat ttgtttactt ttaactttgt 66120
tatatgaaac aagagcaata tatagatgct gtaaaattac cattaagtgt tccacaacaa 66180
aataatagca cgtagtttta aaatgggcat cagggagatt taatagtgac agaatctgat 66240
ttatattggt cttgattatt tgataaaggc aaggttgggc acaaacattg ttttgaaaac 66300
agattatagc tctctgtgta ttttctgttt gctattgtcc attttccctt tagaatctgt 66360
tgatttattt tgtactgatt tacccaacag agtgttcttc tgctgttgac atgtgaggtt 66420
ggatggcatg tactgtaatc ctcatggaca gacgagacgt acagtagcat gttgaacccg 66480
agggtcagaa gggcactgat gcatgctgat caagtgtgga gattaggcca gattccagtt 66540
gtaattacaa tggtgaatcc actctccaga tggatgcttt tacaagcgag cacaagaagg 66600
atggtccaca cgtctctgag agttgatggc tttgaggaaa gccgcttatg tttaatgggg 66660
ggacgagtat caccagtcta ttgcgtctcc agcctttgac ttcatcgtta atgcctggag 66720
atcatacttt taatgctgtt gtcccctgca tttgactctg ccataatgtt caaagactta 66780
cactttaata ccacttcgat gaagcgggta acatgcctgc cacgctcctc agcaggagag 66840
cttttgagac ccctgctgtt cagaatagaa tcccacacac acacacgcac gcacgcacac 66900
acacagccac acacacacac acacaaacaa atgcactaca gaagtgggta taatgcaaaa 66960
ctgctcggaa attgtcctat gagcaacaaa ggaggaatga aacagagaga gatgctgggt 67020
gatgttgagt gatgaacttt cagtagaaca caagaatgcg gtctttcatt aagaaaaaac 67080
actaagcaga ttcttttccc aaaagctttg tgttgaattc tcccttcaaa cagagtgggt 67140
tttataggct ctctaagttt caattttcat cttcttaaga actttcatgt agggactcat 67200
gatattaacc tctctgtatt ctatttcaca gattgggctt ccccatgatg ctgatgacct 67260
gtacgatagc catgtgctac cttcttgcaa ctcacatcgg acttcactgg aacact 67316
<210> 4
<211> 839
<212> PRT
<213> Carassius auratus
<400> 4
Met Tyr Leu Glu Asn Lys Ser Asn Ile Glu Val Glu Met Ser Gln Thr
1 5 10 15
Gly Gly Gln Gly His Ser Ser Arg Val Gly Cys Arg Lys Ser Asp Thr
20 25 30
Val Ala Gly Asn Phe Asp Glu Leu Arg Leu Leu Glu Gly Phe Ser Gly
35 40 45
Lys Ile Glu Thr Gln Lys Ser Leu Gln Ala Ala Ala Met Pro Ser Gly
50 55 60
Asn Cys Ile Ile Tyr Thr Asp Val His Gln Asp Asp Arg His Ser Phe
65 70 75 80
Ser Met Val Asn Leu Leu Lys Asp Lys Ser Asn Gln Ala Asn His Thr
85 90 95
Glu Arg Ser Pro Leu Leu Lys Phe Pro Gln Asn Asp Ser Ile Thr Tyr
100 105 110
Met Thr Leu His Glu Pro Ser Leu Gly Ser Gly Glu Glu Ser Trp Glu
115 120 125
Ala Ser Ser Ala Glu Leu Glu Arg Arg Cys Arg Leu Gly Ser Glu Val
130 135 140
Thr Ser Leu Ser His Ile Thr Ser Met Glu Lys Cys Glu His Tyr Phe
145 150 155 160
Lys Leu Ser Phe Pro Ile Arg His Cys Leu Arg Thr Thr Lys Ile Ile
165 170 175
Thr Ile Phe Ile Ile Val Val Leu Cys Ser Leu Phe Phe Ser Met Tyr
180 185 190
Pro Asp Arg Glu Ser Pro Trp Arg Met Leu Ala Phe Leu Asp Ile Phe
195 200 205
Leu Asn Pro Thr Asp Arg Val Ala Met Asn Leu Thr Asp Phe Arg Asp
210 215 220
Asn Ser Leu Leu Lys Leu Gln Val Gly Gly Pro Phe Leu Gly Gly Met
225 230 235 240
Glu Ala Val Gln Glu Ala Gln Glu Tyr Ile Leu Ile Gln Val Glu Gln
245 250 255
Thr Glu Glu Ala Gly Ser Arg Arg Arg Arg Thr Gln Gln Val Leu Tyr
260 265 270
Asn Trp Thr Ile Pro Leu His Ser Gln Arg Ser Asp Gln Ile Leu Arg
275 280 285
Thr Arg Thr Phe Glu Met Val Ser Ser Ala His Ile Leu Ile Ser Val
290 295 300
Gln Ala Phe Leu Leu Asp Ser Gln Val Val Pro Leu Ser Met Thr His
305 310 315 320
Gln Ser Leu Tyr Val Thr Val Glu Thr Gln Val Leu Ile Ala Gly Leu
325 330 335
Ile Leu Ala Gly Val Tyr Val Leu Ile Ile Phe Glu Ile Val His Arg
340 345 350
Thr Leu Ala Ala Met Leu Gly Ser Leu Ala Ala Leu Ala Ala Leu Ala
355 360 365
Phe Ile Gly Asp Arg Pro Ser Leu Met Thr Val Val Glu Trp Ile Asp
370 375 380
Tyr Glu Thr Leu Ala Leu Leu Phe Gly Met Met Ile Leu Val Ala Ile
385 390 395 400
Phe Ser Glu Thr Gly Phe Phe Asp Tyr Cys Ala Val Lys Ala Tyr Gln
405 410 415
Leu Ser Arg Gly Arg Val Trp Pro Met Ile Met Ile Leu Cys Leu Ile
420 425 430
Ala Ala Val Leu Ser Ala Phe Leu Asp Asn Val Thr Thr Met Met Leu
435 440 445
Phe Thr Pro Val Thr Ile Arg Leu Cys Glu Val Leu Asn Leu Asp Pro
450 455 460
Arg His Val Leu Ile Ala Glu Val Ile Phe Thr Asn Ile Gly Gly Ala
465 470 475 480
Ala Thr Ala Val Gly Asp Pro Pro Asn Val Ile Ile Val Ser Asn Gln
485 490 495
Asp Leu Arg Lys Lys Gly Ile Asp Phe Ala Ala Phe Thr Gly Tyr Met
500 505 510
Phe Leu Gly Ile Cys Leu Val Leu Leu Thr Ser Phe Pro Phe Leu Arg
515 520 525
Met Leu Tyr Trp Asn Lys Lys Leu Tyr Asn Lys Glu Ser Ser Glu Ile
530 535 540
Val Glu Leu Lys His Glu Ile Leu Val Trp Arg Gln Thr Ala His Arg
545 550 555 560
Ile Asn Pro Ala Ser Arg Glu Glu Thr Ala Val Lys Cys Leu Leu Met
565 570 575
Gln Lys Val Leu Asn Leu Glu Ser Leu Leu His Lys Lys Leu Lys Thr
580 585 590
Phe Gln Arg Gln Ile Ser Gln Glu Asp Lys Asn Trp Glu His Asn Ile
595 600 605
Gln Glu Leu Gln Lys Lys His Arg Ile Thr Asp Lys Ile Leu Leu Val
610 615 620
Lys Cys Leu Thr Val Leu Gly Val Val Ile Phe Met Phe Phe Leu Asn
625 630 635 640
Ser Phe Val Pro Ala Ile His Leu Glu Leu Gly Trp Ile Ala Ile Leu
645 650 655
Gly Ala Leu Trp Leu Leu Val Leu Ala Asp Ile Gln Asp Phe Glu Ile
660 665 670
Ile Leu His Arg Val Glu Trp Ala Thr Leu Leu Phe Phe Ala Ala Leu
675 680 685
Phe Val Leu Met Glu Ala Leu Ala His Leu Gln Leu Ile Asp Tyr Ile
690 695 700
Gly Glu Gln Thr Ala Val Leu Ile Lys Ala Val Pro Glu Asp Glu Arg
705 710 715 720
Leu Ala Ile Ala Ile Ile Leu Val Met Trp Val Ser Ala Leu Ala Ser
725 730 735
Ser Leu Ile Asp Asn Ile Pro Phe Thr Ala Thr Met Ile Pro Val Leu
740 745 750
Ile Asn Leu Ser Gln Asp Ala Asp Val Asn Leu Pro Ile Lys Pro Leu
755 760 765
Ile Phe Ala Leu Ala Met Gly Ala Cys Leu Gly Gly Asn Gly Thr Leu
770 775 780
Ile Gly Ala Ser Ala Asn Val Val Cys Ala Gly Ile Ala Glu Gln His
785 790 795 800
Gly Tyr Gly Phe Ser Phe Met Glu Phe Phe Arg Leu Gly Phe Pro Met
805 810 815
Met Leu Met Thr Cys Thr Ile Gly Met Cys Tyr Leu Leu Ala Thr His
820 825 830
Ile Gly Leu Gly Trp Asn Thr
835

Claims (10)

1. A preparation method of a rabbit and hundred-pleated skirt Tai lion goldfish is characterized by comprising the following steps:
s1, target point design: carrying out gene sequencing on the golden fish of the Bairuu Taishi lion to obtain a DNA sequence of a gene for regulating and controlling the properties of the rabbit, designing a proper knockout target spot on an exon in the DNA sequence, and transcribing the sequence of the target spot into gRNA in vitro;
the gene for regulating and controlling the rabbit character is a pigment gene oca2, and the sequence of the target point is as follows: GGAGTATATTCTGATCCAGG are provided.
S2, microinjection: flatly paving roes of the golden fish of the Bairuu Taishi in a sterile culture dish, adding a proper amount of ovarian fluid, taking 2 mu L of each mRNA of CRISPR/Cas9 protein and gRNA, uniformly mixing, injecting the mixed mRNA into an egg animal, and injecting 200-grain roes into 4 mu L of mRNA;
s3, fertilization and incubation: and (3) adding the male plectrum aurilave sperms into a culture dish after the injection operation is finished, hatching fertilized eggs after the fertilized eggs are fertilized, and obtaining the plectrum aurilave, namely the plectrum aurilave with the characteristics of a jade rabbit.
2. The method of creating germplasm of a ruffle lion-tuna of claim 1, further comprising the step of gynogenesis, said gynogenesis method comprising: taking the golden fish of the Bai-Shi-Tai lion with the rabbit phenotype in the S3 as a parent, namely an F0 generation, taking carp sperms for inactivation, mixing inactivated semen and the eggs of the female Bai-Shi-Tai lion golden fish of the F0 generation for fertilization, then carrying out shock treatment, and hatching the fertilized eggs to obtain the F1 generation homozygous golden fish of the Bai-Shi-Tai lion with the rabbit trait.
3. The method for creating germplasm of a Bai Kuu Tai lion goldfish as claimed in claim 2, further comprising a high temperature group expanding step, wherein the high temperature group expanding step comprises that after the homozygous roe of the F1 generation emerges from the membrane, part of female fish is raised at a high temperature of 27-28 ℃, so that the female fish is sex-reversed to male fish, and the sex-reversed female fish and the normally raised female fish of the F1 generation are bred, so that the homozygous roe Bai Kuu Tai golden fish filial generation is obtained in batches.
4. The method of claim 1, wherein in step S1, the exon and the intron of the gene for controlling the rabbit trait are designed and obtained according to the DNA sequence of the obtained gene, and the knockout target is designed on the exon sequence of the Baikui Taishi goldfish oca2 gene by using wildcard GG [ G/A ] GG or CC [ T/C ] CC.
5. The method of claim 1, wherein after obtaining the target sequence, a goldfish genome local database is constructed and the uniqueness of the target is determined by searching and determining using blast software before in vitro transcription in step S1.
6. The method for creating germplasm of a Pleurotus Parietini Goldfish according to claim 1, wherein in step S3, the fertilized egg hatching process further comprises the operation of detecting the knockout efficiency, randomly selecting 10 fertilized eggs before membrane emergence, extracting DNA in the fertilized eggs as a template, simultaneously amplifying DNA sequence near the knockout target spot, sequencing and comparing with a normal sequence, calculating the knockout efficiency according to the comparison result, if the knockout efficiency reaches 20% or more, keeping the fertilized eggs in the batch for continuous hatching, and otherwise, terminating the hatching.
7. The method for creating germplasm of a Bai-ruu Tai lion goldfish as claimed in claim 6, wherein said extracting DNA in fertilized egg and amplification specifically comprises: putting the selected fertilized eggs into a PCR tube, adding 70-100 mu L of 50mM NaOH solution, reacting in a PCR instrument at 95 ℃ for 20min, and taking the mixture as a DNA template; designing PCR amplification primers near the knockout target, selecting 10 target clones after PCR amplification, transformation and cloning, sequencing and comparing with a normal sequence to check whether the knockout site is knocked out.
8. The method of claim 2, wherein said female lion goldfish ovum is obtained from the same F0 generation female lion goldfish.
9. The method for creating the germplasm of a hundred-pleated-skirt lion-goldfish as claimed in claim 2, wherein the shock treatment is heat shock, and fertilized eggs are placed in water at 41 ℃ for heat shock for 2min after being developed at a constant temperature of 24 ℃ for 43-47 min.
10. The method for creating the germplasm of a hundred-pleated-skirt lion-goldfish as claimed in claim 2, wherein the shock treatment is cold shock, and the fertilized egg is put into ice water at 0 ℃ for cold shock for 2min after being developed at a constant temperature of 24 ℃ for 3-7 min.
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