CN106381334B - Quality control method and kit for detecting human BRCA1/2 gene variation based on high-throughput sequencing - Google Patents
Quality control method and kit for detecting human BRCA1/2 gene variation based on high-throughput sequencing Download PDFInfo
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Abstract
The invention relates to a quality control method and a kit for detecting human BRCA1/2 gene variation based on high-throughput sequencing, and application thereof. The invention extracts a plurality of genome DNAs of human tumor cell lines with positive BRCA1/2 gene variation, determines the variation positive sites as positive control sites and the wild type sites as negative control sites by a Sanger sequencing method, and mixes the genome DNAs in a certain proportion to obtain a quality control product for detecting the human BRCA1/2 gene variation by high-throughput sequencing. The kit comprises a quality control product for detecting the human BRCA1/2 gene variation.
Description
Technical Field
The invention relates to the field of gene detection, in particular to a quality control method and a kit for detecting BRCA1/2 gene variation based on high-throughput sequencing.
Background
Breast cancer is one of the most common malignant tumors that seriously affect women's health and even life. According to statistics, the incidence rate of the traditional Chinese medicine preparation accounts for 7-10% of various malignant tumors of the whole body. The incidence of breast cancer is often genetically related, and in addition, between the ages of 40-60, the incidence of women is high before and after menopause.
Breast cancer can be divided into two broad categories, sporadic and hereditary. Wherein the hereditary breast cancer accounts for about 5% -10% of the incidence rate of breast cancer. The risk of breast cancer in life was estimated to be 90% for carriers of the BRCA1 or BRCA2 mutant genes, which are genetically mutable in the first family break and the over-family cancer metastasis gene, BRCA1 and BRCA 2. In addition, mutations in BRCA1 and BRCA2 have also been associated with ovarian cancer. All ovarian cancers, with or without family history or age of onset, have mutations in BRCA1 in 2-6% and BRCA2 in 3-4%. Therefore, screening for mutations in the BRCA gene has also received increased attention from researchers.
The genes BRCA1 and BRCA2 are respectively positioned at 17ql2_21 and 13ql2_13, the coding sequences are 5711bp and 10987bp respectively, and the expression has certain tissue specificity. The BRCA1 and BRCA2 proteins consist of 1863 amino acids and 3418 amino acids, respectively, both of which share some of the characteristics of the Granin protein. BRCA1/2 is two genes with effects of inhibiting malignant tumor, and has important effects in regulating human cell replication, repairing genetic material DNA injury, and normal cell growth. Families with this gene mutation tend to have a high incidence of breast cancer, usually at a younger age, with cancer in both breasts and ovarian cancer at the same time. If the structure of BRCA1/2 gene is altered, its function of inhibiting tumorigenesis is affected. By 2013, as many as hundreds of mutations in BRCA1/2 have been found. Scholars summarize the lifetime risks of cancers associated with mutations in BRCA1 and BRCA2 genes, and show that those with mutations in BRCA1 gene have a risk of 50% to 85% and 15% to 45% for breast and ovarian cancers, respectively, and that those with mutations in BRCA2 gene have a risk of 50% to 85% and 10% to 20% for breast and ovarian cancers, respectively.
The BRCA1/2 can be detected to screen high risk groups of breast cancer, ovarian cancer and other related malignant tumors, and is beneficial to early diagnosis and treatment of the diseases.
High throughput Sequencing, also known as Next Generation Sequencing (NGS), can perform Sequencing on hundreds of thousands to millions of DNA molecules at a time, and then compare the Sequencing result with a reference sequence to find mutation information existing on the DNA molecules. The high-throughput sequencing technology is an efficient and accurate gene mutation detection method.
At present, quality control products and kits aiming at BRCA1/2 gene detection are not available at home. The conventional detection of fetal chromosomal aneuploidy (T21, T18, T13) uses a semiconductor sequencing method, and such detection analyzes a variation at the chromosome level depending on the purpose of analysis, and therefore cannot be used for detection analysis aiming at targeted genetic variation. Other gene mutation detection products, such as EGFR hot spot mutation detection, adopt PCR-fluorescence probe method, fluorescence PCR-capillary electrophoresis method, flow fluorescence hybridization method, FISH, sequencing method, Taqman-ARMS method, etc., because only can detect the mutation of a certain specific site, the detection efficiency is low, the cost is high, the mutation of BRCA1/2 gene has no specific hot spot, the incidence rate of the mutation has no obvious site specificity, therefore, the conventional method is not suitable for the screening of the mutation, and can not well meet the requirement of BRCA1/2 gene detection which requires detection and analysis for the whole coding region of the target gene.
Disclosure of Invention
The invention aims to provide a quality control method and a kit for detecting human BRCA1/2 gene variation based on high-throughput sequencing.
According to one aspect of the invention, the preparation method of the quality control product for detecting the human BRCA1/2 gene variation comprises the following steps:
(1) selecting a human tumor cell line with positive BRCA1/2 gene variation and stable passage for culturing, respectively extracting and purifying each cell genome DNA, and respectively diluting the purified DNA to the same concentration to obtain quality control product raw material DNA;
(2) determining potential variation sites on BRCA1/2 gene in each cell line by Sanger sequencing method, and using heterozygous and homozygous variation sites confirmed by Sanger sequencing method as positive control sites;
(3) mixing the DNA of quality control material from different cell lines according to a certain proportion to obtain the quality control material.
The variation frequency value of each potential variation site in the quality control product can be determined according to the mixing proportion and the variation frequency determined by a Sanger sequencing method, and the calculation formula is as follows:
wherein the mixing ratio i refers to the mixing ratio of the genomic DNA of the selected ith cell line in the quality control product, and the variation frequency i refers to the variation frequency of the genomic DNA of the selected ith cell line at the position.
In the above preparation method, the step (2) may be further: potential variation sites on BRCA1/2 gene in each cell line were determined by Sanger sequencing, heterozygous and homozygous variation sites confirmed by Sanger sequencing were used as positive control sites, and sites confirmed to be wild type were used as negative control sites.
In a preferred embodiment, the selected stably passable human tumor cell lines are HCC1599, HCT-15, Jurkat, and NCI-H720 cell lines.
In a further preferred embodiment, the DNA of the quality control raw material obtained from HCC1599, HCT-15, Jurkat and NCI-H720 cell lines is subjected to a DNA sequencing in accordance with 1 to 2:1:1:1 (volume/volume ratio) was mixed uniformly.
It is understood that cell lines used in accordance with the present invention include, but are not limited to, HCC1599, HCT-15, Jurkat, and NCI-H720 cell lines, and that other human tumor cell lines may be used. The DNA of the quality control raw materials obtained from HCC1599, HCT-15, Jurkat and NCI-H720 cell lines may be mixed uniformly in other proportions. The invention can prepare the BRCA1/2 gene variation detection quality control product by selecting different cell lines, configuring different proportions of quality control product raw material DNA and verifying different variation sites. When different cell lines are selected and different proportions of the DNA of the quality control material are configured, the variation sites, wild type sites and/or site variation frequency of the obtained quality control material may be different, but the application of the quality control material as the quality control material is not hindered.
In some embodiments, the culture conditions of the stably passable human tumor cell line are: the culture conditions are as follows: constant temperature of 37 ℃ and 5% CO2And humidity is 50%. Culturing until the cell density reaches 80-90% of the culture dish area.
In some embodiments, the extracting of genomic DNA of the cells refers to collecting the genomic DNA of the cells in the logarithmic phase of cell growth, and extracting the genomic DNA of the cells by centrifuging the precipitate at the speed of 800-.
In some embodiments, purification of cellular genomic DNA refers to column purification and elution.
In a preferred embodiment, the purified DNA is diluted to 100. + -. 5 ng/. mu.L, respectively.
In some embodiments, the purified DNA is diluted with Tris-EDTA buffer.
In a preferred embodiment, the DNA as the quality control material is required to be transparent liquid in appearance without visible impurities and to have a purity of 1.9 > OD260/280 > 1.7.
According to another aspect of the invention, a quality control product for detecting the human BRCA1/2 gene variation obtained by the method is provided.
According to another aspect of the invention, a kit for detecting the human BRCA1/2 gene variation is provided, which comprises the quality control product for detecting the human BRCA1/2 gene variation.
The human BRCA1/2 gene variation detection kit of the invention may also comprise any other components for high throughput sequencing of human BRCA1/2 gene variation. In a preferred embodiment, the human BRCA1/2 gene variation detection kit further comprises one or more reagents selected from the group consisting of a mixture of end-repair enzymes, an end-repair reaction buffer, DNA ligase, a ligation buffer, a linker containing a molecular tag, a library amplification primer, a PCR pre-mix, a linker blocker, a DNA blocker, a hybridization buffer, a hybridization enhancer, a magnetic bead wash, a hybridization wash, a capture library PCR primer, a capture probe, a nucleic acid purification magnetic bead, and a streptavidin magnetic bead. Optionally, the kit for detecting the human BRCA1/2 gene variation can also comprise a negative quality control product. In a particularly preferred embodiment, the human BRCA1/2 gene variation detection kit comprises all of the reagents described above.
According to another aspect of the present invention, there is provided a use of the quality control product for detecting human BRCA1/2 genetic variation or the kit for detecting human BRCA1/2 genetic variation in quality control of high-throughput sequencing detection of human BRCA1/2 genetic variation.
The high-throughput sequencing method is also called second-generation sequencing, and is mainly characterized in that large-scale parallel sequencing can be simultaneously carried out on input sequences, and a large number of short sequence sequencing results are obtained. The basic principle of high-throughput sequencing is to randomly break the DNA to be detected into small fragments, construct a library through the steps of end repair, linker sequence connection, PCR and the like, and finally use sequencers such as Illumina, Ion Torrent and the like to perform sequencing.
The human BRCA1/2 quality control product can be used as a positive quality control product. The human BRCA1/2 quality control product can also be used as a single quality control product simultaneously containing positive control information and negative control information, and the single sample detection can meet the quality control requirement. The human BRCA1/2 quality control product comprises variation sites with different variation frequencies, which is beneficial to controlling and analyzing accuracy. The human BRCA1/2 genetic variation detection quality control product and the kit provided by the invention can effectively evaluate the reliability of a high-throughput sequencing detection system for human BRCA1/2 genetic variation, improve the efficiency and reduce the detection quality control cost.
Detailed Description
The test methods used in the following examples are all conventional methods unless otherwise specified.
Materials and reagents used in the following examples are commercially available unless otherwise specified.
Example 1: preparation of quality control product for detecting human BRCA1/2 gene variation
1.1. Four commonly used stably passable human tumor cell lines HCC1599, HCT-15, Jurkat, NCI-H720 were purchased from the ATCC.
1.2. The four human tumor cell lines are cultured by adopting a special culture medium under the culture conditions: constant temperature of 37 ℃ and 5% CO2And humidity is 50%. Culturing until the cell density reaches 80-90% of the culture dish area, collecting in the logarithmic phase of cell growth, centrifuging at the speed of 800-.
1.3. And (3) respectively diluting the purified genome DNA of each cell line to 100 +/-5 ng/mu L by using Tris-EDTA buffer solution, wherein the purified genome DNA is transparent liquid without visible impurities, and the purity is 1.9-OD 260/280-1.7, so that the quality control product raw material DNA is obtained.
1.4. The genomic DNA of each cell line was sequenced by Sanger sequencing, and the sites of heterozygous and homozygous variation confirmed by Sanger method served as positive control sites. The test result shows that the mutant contains 27 positive variant sites and 660 wild type sites.
1.5. The quality control raw material DNA of four cell lines HCC1599, HCT-15, Jurkat and NCI-H720 is subjected to the following steps of 1:1: 1:1, and storing at-20 ℃.
Example 2: preparation of human BRCA1/2 gene variation detection kit
2.1. Designing and synthesizing a plurality of capture probes directed to different target regions on human BRCA1/2 gene, the collection of all capture probes being capable of covering all coding exon regions and exon intron junction regions of human BRCA1/2 gene; the capture probe is provided with a biotin label; the sequences of the capture probes are shown in table 1.
TABLE 1 human BRCA1/2 Gene variation detection hybrid Capture Probe sequences
2.2. All the above capture probes were mixed together in the same mass and the mixture was diluted to a working concentration of 1.5PM (PM ═ picomoles/liter), stored at-20 ℃.
2.3. The capture probe mixture and the quality control product obtained in example 1 were separately dispensed.
2.4. Preparing a specification and an outer package, and assembling and sealing.
2.5. Wherein the dosage of the capture probe mixture is 6 muL/3 reaction, 12 muL/6 reaction, 24 muL/12 reaction and 48 muL/24 reaction; the dosage of quality control material is 5 μ L/3 reaction, 10 μ L/6 reaction, 20 μ L/12 reaction, and 40 μ L/24 reaction.
Example 3: sequencing detection of human BRCA1/2 gene variation
The instrument used for sequencing in this example was NextSeq 500.
The preparation method of the positive quality control material is the same as that of example 1.
3.1. Human genome DNA is extracted from 20 positive blood samples, and positive quality control products are directly used without extraction.
Fragmentation of DNA samples and quality controls
Taking 200ng of each human genome DNA sample, taking 200ng of quality control products, supplementing less than 50 mu L of available PCR-gradewater to 50 mu L, shaking, mixing uniformly, and centrifuging briefly. And then transferring the solution into a microtube completely, and selecting an interrupt program with the fragment length of 200-300 bp to fragment the genomic DNA sample and the quality control DNA. 5. mu.L of the fragmented sample was subjected to agarose gel electrophoresis.
3.3. Library construction
3.3.1. End repair and splice connection
And (3) adding 200-400 ng of the broken genome DNA sample or quality control product into a 0.2ml PCR reaction tube, filling the mixture to 50 mu L by using PCR-grade water, shaking and uniformly mixing the mixture, and centrifuging the mixture for a short time. Respectively adding 3 mu L of terminal repair enzyme mixture and 7 mu L of terminal repair reaction buffer solution, shaking, uniformly mixing, centrifuging for a short time, and then preserving heat at 20 ℃ for 30min, and then preserving heat at 65 ℃ for 30min to carry out terminal repair. The PCR reaction tube was removed, centrifuged briefly, and then 2. mu.L of adaptor (containing index tag), 10. mu.L of DNA ligase, 30. mu.L of ligation buffer, and 8. mu.L of PCR-grade water were added, respectively. Shaking and mixing, centrifuging for a short time, keeping the temperature at 20 ℃ for 15min, and performing joint connection.
3.3.2. Purification of
And taking the nucleic acid purification magnetic beads, and balancing to room temperature. And (3) taking the PCR reaction tube connected with the joint in the step 3.3.1, centrifuging for a short time, and transferring all products into a 1.5mL centrifuge tube. Then adding 99 mu L of nucleic acid purification magnetic beads, shaking and uniformly mixing, standing for 5min at room temperature, then centrifuging briefly, transferring to a magnetic frame, standing for 1min, and absorbing and removing the supernatant. Then, 200. mu.L of 80% ethanol was added, and after standing for 1min, the supernatant was aspirated. Washing is repeated once, and the mixture is left standing for 3min after being uncovered. Add 22. mu.L of nucleic-free water resuspension magnetic beads to the tube, let stand at room temperature for 5min, transfer to magnetic stand and let stand for 1min, and take 20. mu.L of supernatant to a new 0.2ml PCR reaction tube for use.
3.3.3. Library amplification and purification
Adding 25 μ L of 2 XPCR premix and 5 μ L of library amplification primers into the 0.2ml PCR reaction tube filled with 20 μ L of supernatant in the step 3.3.2, shaking and mixing uniformly, performing amplification in a PCR instrument according to the following procedures after short-time centrifugation: 1min at 98 ℃; 7-9 cycles, each cycle being 98 ℃ for 15s, 60 ℃ for 30s, and 72 ℃ for 30 s; 1min at 72 ℃; storing at 4 deg.C for use. And (4) taking out the PCR reaction tube after amplification, and transferring all amplification products into a 1.5mL centrifuge tube after short-time centrifugation. Adding 45 mu L of nucleic acid purification magnetic beads into a centrifuge tube, shaking and uniformly mixing, standing at room temperature for 5min, then centrifuging briefly, transferring to a magnetic frame, standing for 1min, and absorbing and removing the supernatant. Then, 200. mu.L of 80% ethanol was added thereto, and after standing for 30 seconds, the supernatant was aspirated. Washing is repeated once, and the mixture is left standing for 3min after being uncovered. Add 52. mu.L of nucleic-free water to the centrifuge tube, let stand at room temperature for 5min, transfer to the magnetic frame, let stand for 1min, and take 50. mu.L of supernatant to a new 1.5mL centrifuge tube for use. mu.L of library DNA or quality control DNA was taken and quantified (using a Qubit fluorescence quantifier).
3.4. Library Capture
3.4.1. Hybridization of
Mixing 8 libraries in a sample pool for hybridization capture, mixing less than 8 libraries in a sample pool for hybridization capture, mixing the libraries in a 1.5mL Lobind centrifuge tube to form a sample pool, wherein the dosage of a blood sample is not less than 125ng, and the total amount of the sample pool is not more than 1 mug. Adding 2 mu L of linker sealing agent and 5 mu L of DNA sealing agent into the sample cell, shaking and uniformly mixing, centrifuging for a short time, and freezing and vacuum-pumping to dry. Add 8.5. mu.L hybridization buffer (2X), 2.7. mu.L hybridization enhancer and 3.8. mu.L PCR-grade water, mix well with shaking, centrifuge briefly, and then let stand at room temperature for 5min to redissolve. The redissolved solution was transferred to a new 0.2mL PCR reaction tube and incubated at 95 ℃ for 10 minutes. Taking out the PCR reaction tube, adding 2 mu L of the capture probe mixture obtained in the example 2 after short-time centrifugation, shaking and uniformly mixing for 3-5s, preserving the temperature at 65 ℃ for 4h after short-time centrifugation, and keeping the temperature of a hot cover at 75 ℃.
3.4.2. Enrichment of
And washing streptavidin magnetic beads, adding 1 volume of magnetic bead washing solution, shaking for resuspension, and subpackaging 100 mu L of each tube into different 0.2mL PCR reaction tubes.
And (3) taking out the PCR reaction tube in the step (3.4.1), centrifuging for a short time, transferring all the hybridization products to the PCR reaction tube containing streptavidin magnetic beads, fully suspending, incubating at 65 ℃ for 45min on a PCR instrument, and sucking and uniformly mixing every 12 min. After the incubation is finished, 100 μ L of 1 × lotion I preheated at 65 ℃ is added into each tube, the whole suspension is transferred into a 1.5mL Lobind centrifuge tube, the mixture is uniformly mixed by shaking, the mixture is transferred to a magnetic frame after short-time centrifugation and is kept stand for 20s, and the supernatant is removed by suction.
Adding 200 μ L of 1 × hybridization washing solution preheated at 65 deg.C, shaking, mixing, centrifuging for a short time, incubating at 65 deg.C for 5min, transferring to magnetic frame, standing for 20s, and removing supernatant. This step was repeated once.
Then, after the mixture was sufficiently eluted with a magnetic bead washing solution, 18. mu.L of nucleic-free water was added thereto, and the mixture was shaken to resuspend the mixture, and then the whole mixture was transferred to a 0.2mL PCR reaction tube for further use.
3.4.3. Capture library amplification and purification
Adding 25 μ L of 2 XPCR premix and 2.5 μ L of capture library PCR primers into the PCR reaction tube respectively, mixing thoroughly, centrifuging briefly, and performing PCR amplification according to the following procedures: 3min at 95 ℃; 10 cycles, each cycle being 98 ℃ for 20s, 60 ℃ for 30s, 72 ℃ for 30 s; 1min at 72 ℃; storing at 4 deg.C for use.
After the PCR reaction tube was briefly centrifuged, the product was transferred to a 1.5mL centrifuge tube in its entirety. Adding 75 mu L of nucleic acid purification magnetic beads, shaking and uniformly mixing, standing at room temperature for 10min, then centrifuging briefly, transferring to a magnetic frame, standing for 1min, and absorbing and removing the supernatant. 200 μ L of 80% ethanol was added, and after standing for 30 seconds, the supernatant was aspirated. And (5) repeatedly washing once, uncovering and drying until no liquid drops are left. Adding 21.6 mu L of luclease-free water, shaking the resuspended magnetic beads, standing at room temperature for 5min, transferring to a magnetic frame, standing for 1min, and taking 20 mu L of supernatant to a new 1.5mL Lobind centrifuge tube for later use. mu.L of the captured library or the captured quality control DNA was taken for quantification (using a Qubit fluorescence quantifier).
3.5. Sequencing and data analysis
3.5.1. Sequencing
And performing on-machine sequencing according to the use instructions of the sequencing instrument and the matched reagent. Average effective depth of coverage: blood samples are greater than or equal to 300X.
3.5.2. Data analysis
After the original sequencing data are obtained, the obtained data are compared with a reference database for mutation analysis and interpretation.
The detection results are as follows:
the mutation sites and the detection results of the clinical samples are shown in Table 1. Clinical sample detection compliance rate: 20/20 is 100%. All clinical samples were verified to be error free by Sanger sequencing.
TABLE 1 clinical samples mutation sites and test results
The detection results of the variation positive sites and the negative (i.e., wild type) sites of the positive quality control products are shown in tables 2 and 3, wherein the reference mutation frequency is a theoretical variation frequency value obtained by calculation according to the mixing ratio and the variation frequency determined by a Sanger sequencing method, and the detection value is a high-throughput sequencing experiment detection result.
TABLE 2 variation sites and test results of quality control products
TABLE 3 variation negative sites and detection results of quality control products
As can be seen from the results in tables 2 and 3, the positive control corresponds to 100% of the positive control, and the wild-type sequence corresponds to 100% of the positive control.
Example 4: repeatability test
A positive control B-P1 was prepared according to the method of example 1, except that four cell line DNAs were mixed at a volume ratio of 2:1:1:1 in example 1.
Three batches of the kit were produced according to the preparation method of example 2, batch numbers 20160126, 20160127, 20160128, respectively.
High throughput sequencing assays were performed according to the assay method of example 3. The same batch of kit 20160126 detects B-P1 three times, and the detection results are shown in Table 4. The different batches of kits 20160126, 20160127, 20160128, detect B-P1 1 time each, and the detection results are shown in Table 5.
TABLE 4 Intra-batch differences
| Batch number | Sample name | Percent of positive variation | Percent sequence identity of wild type |
| 20160126 | B-P1 | 100％ | 100％ |
| 20160126 | B-P1 | 100％ | 100％ |
| 20160126 | B-P1 | 100％ | 100％ |
TABLE 5 inter-batch differences
| Batch number | Sample name | Percent of positive variation | Percent sequence identity of wild type |
| 20160126 | B-P1 | 100％ | 100％ |
| 20160127 | B-P1 | 100％ | 100％ |
| 20160128 | B-P1 | 100％ | 100％ |
And (3) detection results: the repeatability of the kit meets the requirement.
SEQUENCE LISTING
<110> Angio Biotechnology (Shanghai) Ltd
<120> quality control method and kit for detecting human BRCA1/2 gene variation based on high-throughput sequencing
<130>201610824194.6
<160>631
<170>PatentIn version 3.5
<210>1
<211>120
<212>DNA
<213> Artificial sequence
<400>1
aaaaaaatca agaagaaact acttcaattt caaaaataac tgtcaatcca gactctgaag 60
aacttttctc agacaatgag aataattttg tcttccaagt agctaatgaa aggaataatc 120
<210>2
<211>120
<212>DNA
<213> Artificial sequence
<400>2
aaaaacgata aatggcacca agaaaatgaa atactttgag aagctttcca ttaaatgaaa 60
atatatcata caaattaatt ttagcacagg aattgaaatc acctagtatg gaactacaag 120
<210>3
<211>120
<212>DNA
<213> Artificial sequence
<400>3
aaaaagtaag aactagcaag actaggaaaa aaattttcca tgaagcaaac gctgatgaat 60
gtgaaaaatc taaaaaccaa gtgaaagaaa aatactcatt tgtatctgaa gtggaaccaa 120
<210>4
<211>120
<212>DNA
<213> Artificial sequence
<400>4
aaaaagtatc tttttgaaag ttaaagtaca tgaaaatgta gaaaaagaaa cagcaaaaag 60
tcctgcaact tgttacacaa atcagtcccc ttattcagtc attgaaaatt cagccttagc 120
<210>5
<211>112
<212>DNA
<213> Artificial sequence
<400>5
aaaaagtggc cattattgaa cttacagatg ggtggtatgc tgttaaggcc cagttagatc 60
ctcccctctt agctgtctta aagaatggca gactgacagt tggtcagaag at 112
<210>6
<211>118
<212>DNA
<213> Artificial sequence
<400>6
aaaaatcatc tctccgaaaa acaagatact tatttaagta acagtagcat gtctaacagc 60
tattcctacc attctgatga ggtatataat gattcaggat atctctcaaa aaataaac 118
<210>7
<211>111
<212>DNA
<213> Artificial sequence
<400>7
aaaaatgact gtaacaaaag tgcttctggt tatttaacag atgaaaatga agtggggttt 60
aggggctttt attctgctca tggcacaaaa ctgaatgttt ctactgaagc t 111
<210>8
<211>120
<212>DNA
<213> Artificial sequence
<400>8
aaaataaaaa tgcagccatt aaattgtcca tatctaatag taataatttt gaggtagggc 60
cacctgcatt taggatagcc agtggtaaaa tcgtttgtgt ttcacatgaa acaattaaaa 120
<210>9
<211>119
<212>DNA
<213> Artificial sequence
<400>9
aaaataactc tcctgaacat ctaaaagatg aagtttctat catccaaagt atgggctaca 60
gaaaccgtgc caaaagactt ctacagagtg aacccgaaaa tccttccttg gtaaaacca 119
<210>10
<211>120
<212>DNA
<213> Artificial sequence
<400>10
aaaatatttc agaaaaagac ctattagaca cagagaacaa aagaaagaaa gattttctta 60
cttcagagaa ttctttgcca cgtatttcta gcctaccaaa atcagagaag ccattaaatg 120
<210>11
<211>114
<212>DNA
<213> Artificial sequence
<400>11
aaaatgaaga taacaaatat actgctgcca gtagaaattc tcataactta gaatttgatg 60
gcagtgattc aagtaaaaat gatactgttt gtattcataa agatgaaacg gact 114
<210>12
<211>120
<212>DNA
<213> Artificial sequence
<400>12
aaaatgtaga aaaagaaaca gcaaaaagtc ctgcaacttg ttacacaaat cagtcccctt 60
attcagtcat tgaaaattca gccttagctt tttacacaag ttgtagtaga aaaacttctg 120
<210>13
<211>117
<212>DNA
<213> Artificial sequence
<400>13
aaaatgtttt taaagaagcc agctcaagca atattaatga agtaggttcc agtactaatg 60
aagtgggctc cagtattaat gaaataggtt ccagtgatga aaacattcaa gcagaac 117
<210>14
<211>120
<212>DNA
<213> Artificial sequence
<400>14
aaacacaaca aaaccatatt taccatcacg tgcactaaca agacagcaag ttcgtgcttt 60
gcaagatggt gcagagcttt atgaagcagt gaagaatgca gcagacccag cttaccttga 120
<210>15
<211>120
<212>DNA
<213> Artificial sequence
<400>15
aaaccaaacc catgcaaaag gaccccatat agcacaggta catgcaggca ccttaccatg 60
gaagccattg tcctctgtcc aggcatctgg ctgcacaacc acaattgggt ggacaccctg 120
<210>16
<211>120
<212>DNA
<213> Artificial sequence
<400>16
aaacctttca ttgtaatttt tcagttttga taagtgcttg ttagtttatg gaatctccat 60
atgttgaatt tttgttttgt tttctgtagg tttcagatga aattttattt cagatttacc 120
<210>17
<211>120
<212>DNA
<213> Artificial sequence
<400>17
aaactagttt ttgccagttt tttaaaataa cctaagggat ttgctttgtt ttattttagt 60
cctgttgttc tacaatgtac acatgtaaca ccacaaagag ataagtcagg tatgattaaa 120
<210>18
<211>120
<212>DNA
<213> Artificial sequence
<400>18
aaactgtaag tgaaaaaaat aataaatgcc aactgatatt acaaaataat attgaaatga 60
ctactggcac ttttgttgaa gaaattactg aaaattacaa gagaaatact gaaaatgaag 120
<210>19
<211>120
<212>DNA
<213> Artificial sequence
<400>19
aaagagctaa catacagtta gcagcgacaa aaaaaactca gtatcaacaa ctaccggtac 60
aaacctttca ttgtaatttt tcagttttga taagtgcttg ttagtttatg gaatctccat 120
<210>20
<211>120
<212>DNA
<213> Artificial sequence
<400>20
aaaggttgtg agaataatat aaattatatg gcttataaaa tattaatgtg cttctgtttt 60
atactttaac aggatttgga aaaacatcag ggaattcatt taaagtaaat agctgcaaag 120
<210>21
<211>130
<212>DNA
<213> Artificial sequence
<400>21
aaataaatta ttgagcctca tttattttct ttttctcccc ccctaccctg ctagtctgga 60
gttgatcaag gaacctgtct ccacaaagtg tgaccacata ttttgcaagt aagtttgaat 120
gtgttatgtg 130
<210>22
<211>120
<212>DNA
<213> Artificial sequence
<400>22
aaataatatc cttaatgatc agggcatttc tataaaaaat aaactatttt ctttcctccc 60
agggtcgtca gacaccaaaa catatttctg aaagtctagg agctgaggtg gatcctgata 120
<210>23
<211>120
<212>DNA
<213> Artificial sequence
<400>23
aaatacaagg gaaaacatta tgtttgcagt tagagaaaaa tgtatgaatt ataatcaaag 60
aaaccaagag aaaccctatg tatgctcttt gttgtgttaa gacaatgcat taaggttacc 120
<210>24
<211>120
<212>DNA
<213> Artificial sequence
<400>24
aaatacatac tgtttgctca cagaaggagg actccttatg tccaaattta attgataatg 60
gaagctggcc agccaccacc acacagaatt ctgtagcttt gaagaatgca ggtttaatat 120
<210>25
<211>120
<212>DNA
<213> Artificial sequence
<400>25
aaataccaga aaaaaataat gattacatga acaaatgggc aggactctta ggtccaattt 60
caaatcacag ttttggaggt agcttcagaa cagcttcaaa taaggaaatc aagctctctg 120
<210>26
<211>130
<212>DNA
<213> Artificial sequence
<400>26
aaatatttct ttttaggaga accctcaatc aaaagaaact tattaaatga atttgacagg 60
ataatagaaa atcaagaaaa atccttaaag gcttcaaaaa gcactccaga tggtaaaatt 120
agctttttat 130
<210>27
<211>104
<212>DNA
<213> Artificial sequence
<400>27
aaatctaaaa gtaaatctga aagagctaac atacagttag cagcgacaaa aaaaactcag 60
tatcaacaac taccggtaca aacctttcat tgtaattttt cagt 104
<210>28
<211>120
<212>DNA
<213> Artificial sequence
<400>28
aaatggaaaa aacctgcagt aaagaattta aattatcaaa taacttaaat gttgaaggtg 60
gttcttcaga aaataatcac tctattaaag tttctccata tctctctcaa tttcaacaag 120
<210>29
<211>120
<212>DNA
<213> Artificial sequence
<400>29
aaatggtttt gtcaaattca agaattggaa aaagaagagg agagcccctt atcttagtgg 60
gtaagtgttc atttttacct ttcgtgttgc caatcactat ttttaaagtg tttattcagt 120
<210>30
<211>121
<212>DNA
<213> Artificial sequence
<400>30
aaatttttta ggatctgatt cttctgaaga taccgttaat aaggcaactt attgcaggtg 60
agtcaaagag aacctttgtc tatgaagctg gtattttcct atttagttaa tattaaggat 120
t 121
<210>31
<211>120
<212>DNA
<213> Artificial sequence
<400>31
aacaaaaaca actccaatca agcagtagct gtaactttca caaagtgtga agaagaacct 60
ttaggtattg tatgacaatt tgtgtgatga atttttgcct ttcagttaga tatttccgtt 120
<210>32
<211>120
<212>DNA
<213> Artificial sequence
<400>32
aacaactatc aatttgcaat tcagtacaat taggtgggct tagatttcta ctgactacta 60
gttcaagcgc atgaatatgc ctggtagaag acttcctcct cagcctattc tttttaggtg 120
<210>33
<211>120
<212>DNA
<213> Artificial sequence
<400>33
aacaatgctt tttattctta gaatactaga aatgttaata aaaataaaac ttaacaattt 60
tccccttttt ttacccccag tggtatgtgg gagtttgttt catacaccaa agtttgtgaa 120
<210>34
<211>113
<212>DNA
<213> Artificial sequence
<400>34
aacaatttaa tttcaggagc ctacaagaaa gtacgagatt tagtcaactt gttgaagagc 60
tattgaaaat catttgtgct tttcagcttg acacaggttt ggagtgtaag tgt 113
<210>35
<211>120
<212>DNA
<213> Artificial sequence
<400>35
aacagttacc agaatagtat caccatgtag caaatgaggg tctgcaacaa aggcatattc 60
ctaaatattt atatgtgtac tagtcaataa acttatatat tttctcccca ttgcagcaca 120
<210>36
<211>120
<212>DNA
<213> Artificial sequence
<400>36
aacataacat taagaagagc aaaatgttct tcaaagatat tgaagaacaa tatcctacta 60
gtttagcttg tgttgaaatt gtaaatacct tggcattaga taatcaaaag aaactgagca 120
<210>37
<211>120
<212>DNA
<213> Artificial sequence
<400>37
aacattcaga ccagctcaca agagaagaaa atactgctat acgtactcca gaacatttaa 60
tatcccaaaa aggcttttca tataatgtgg taaattcatc tgctttctct ggatttagta 120
<210>38
<211>120
<212>DNA
<213> Artificial sequence
<400>38
aaccagaaag aataaatact gcagattatg taggaaatta tttgtatgaa aataattcaa 60
acagtactat agctgaaaat gacaaaaatc atctctccga aaaacaagat acttatttaa 120
<210>39
<211>120
<212>DNA
<213> Artificial sequence
<400>39
aaccagaata ttcatctacc tcatttagaa cgtccaatac atcagctact ttggcatttg 60
attcagactc cccatcatgt gagtcatcag aacctaacag ttcatcactt ctggaaaacc 120
<210>40
<211>113
<212>DNA
<213> Artificial sequence
<400>40
aaccagtctc agtgtccaac tctctaacct tggaactgtg agaactctga ggacaaagca 60
gcggatacaa cctcaaaaga cgtctgtcta cattgaattg ggtaagggtc tca 113
<210>41
<211>115
<212>DNA
<213> Artificial sequence
<400>41
aacgtgatga aaagatcaaa gaacctactc tattgggttt tcatacagct agcgggaaaa 60
aagttaaaat tgcaaaggaa tctttggaca aagtgaaaaa cctttttgat gaaaa 115
<210>42
<211>120
<212>DNA
<213> Artificial sequence
<400>42
aactaccctg atacttttct ggatgcctct cagctgcacg cttctcagtg gtgttcaaat 60
cattattact gggttgatga tgttcagtat ttgttacatc cgtctcagaa aattcacaag 120
<210>43
<211>120
<212>DNA
<213> Artificial sequence
<400>43
aactagtatc ttcctttatt tcaccatcat ctaacaggtc atcaggtgtc tcagaacaaa 60
cctgagatgc atgactactt cccataggct gttctaagtt atctgaaatc agatatggag 120
<210>44
<211>111
<212>DNA
<213> Artificial sequence
<400>44
aacttagaac agcctatggg aagtagtcat gcatctcagg tttgttctga gacacctgat 60
gacctgttag atgatggtga aataaaggaa gatactagtt ttgctgaaaa t 111
<210>45
<211>120
<212>DNA
<213> Artificial sequence
<400>45
aacttttctc agacaatgag aataattttg tcttccaagt agctaatgaa aggaataatc 60
ttgctttagg aaatactaag gaacttcatg aaacagactt gacttgtgta aacgaaccca 120
<210>46
<211>120
<212>DNA
<213> Artificial sequence
<400>46
aacttttttg ttctgattgc tttttattcc aatatcttaa atggtcacag ggttatttca 60
gtgaagagca gttaagagcc ttgaataatc acaggcaaat gttgaatgat aagaaacaag 120
<210>47
<211>120
<212>DNA
<213> Artificial sequence
<400>47
aagaagaaga agaagaagaa aacaaatggt tttaccaagg aaggattttc gggttcactc 60
tgtagaagtc ttttggcacg gtttctgtag cccatacttt ggatgataga aacttcatct 120
<210>48
<211>118
<212>DNA
<213> Artificial sequence
<400>48
aagaagagca aaatgttctt caaagatatt gaagaacaat atcctactag tttagcttgt 60
gttgaaattg taaatacctt ggcattagat aatcaaaaga aactgagcaa gcctcagt 118
<210>49
<211>120
<212>DNA
<213> Artificial sequence
<400>49
aagaagattt gtcagattta acttttttgg aagttgcgaa agctcaagaa gcatgtcatg 60
gtaatacttc aaataaagaa cagttaactg ctactaaaac ggagcaaaat ataaaagatt 120
<210>50
<211>119
<212>DNA
<213> Artificial sequence
<400>50
aagaatgagt ctaatatcaa gcctgtacag acagttaata tcactgcagg ctttcctgtg 60
gttggtcaga aagataagcc agttgataat gccaaatgta gtatcaaagg aggctctag 119
<210>51
<211>120
<212>DNA
<213> Artificial sequence
<400>51
aagaatgtgg gatacatact actgaatgca aaggacacca cacacacgca tgtgcacaca 60
cacacacgct ttttacctga gtggttaaaa tgtcactctg agaggatagc cctgagcagt 120
<210>52
<211>120
<212>DNA
<213> Artificial sequence
<400>52
aagattcagg taagtatgta aatgctttgt ttttatcagt tttattaact taaaaaatga 60
ccttactaac aaaatgatta taaatccaga taaagtataa agttagttta tatcagagaa 120
<210>53
<211>120
<212>DNA
<213> Artificial sequence
<400>53
aagcaaatgc ttttgaagca ccacttacat ttgcaaatgc tgattcaggt acctctgtct 60
tttttttttt gtaaatagta catatagttt tatagatgac gattccttct gtgttttttt 120
<210>54
<211>113
<212>DNA
<213> Artificial sequence
<400>54
aagcacctaa aaagaatagg ctgaggagga agtcttctac caggcatatt catgcgcttg 60
aactagtagt cagtagaaat ctaagcccac ctaattgtac tgaattgcaa att 113
<210>55
<211>120
<212>DNA
<213> Artificial sequence
<400>55
aaggaaaaaa aataccgaaa gaccaaaaat cagaactaat taactgttca gcccagtttg 60
aagcaaatgc ttttgaagca ccacttacat ttgcaaatgc tgattcaggt acctctgtct 120
<210>56
<211>120
<212>DNA
<213> Artificial sequence
<400>56
aaggagataa aggggaagga aagaattttg cttaagatat cagtgtttgg ccaacaatac 60
acaccttttt ctgatgtgct ttgttctgga tttcgcaggt cctcaagggc agaagagtca 120
<210>57
<211>118
<212>DNA
<213> Artificial sequence
<400>57
aagtaaaaat gatactgttt gtattcataa agatgaaacg gacttgctat ttactgatca 60
gcacaacata tgtcttaaat tatctggcca gtttatgaag gagggaaaca ctcagatt 118
<210>58
<211>120
<212>DNA
<213> Artificial sequence
<400>58
aagtacttac ctcattcagc atttttcttt ctttaataga ctgggtcacc cctaaagaga 60
tcatagaaaa gacaggttac atacagcaga agaacgtgct cttttcacgg agatagagag 120
<210>59
<211>120
<212>DNA
<213> Artificial sequence
<400>59
aagtgaaaaa cctttttgat gaaaaagagc aaggtactag tgaaatcacc agttttagcc 60
atcaatgggc aaagacccta aagtacagag aggcctgtaa agaccttgaa ttagcatgtg 120
<210>60
<211>120
<212>DNA
<213> Artificial sequence
<400>60
aagtgaaaga catatttaca gacagtttca gtaaagtaat taaggaaaac aacgagaata 60
aatcaaaaat ttgccaaacg aaaattatgg caggttgtta cgaggcattg gatgattcag 120
<210>61
<211>120
<212>DNA
<213> Artificial sequence
<400>61
aagtttctaa aatatcacct tgtgatgtta gtttggaaac ttcagatata tgtaaatgta 60
gtatagggaa gcttcataag tcagtctcat ctgcaaatac ttgtgggatt tttagcacag 120
<210>62
<211>115
<212>DNA
<213> Artificial sequence
<400>62
aataatatcc ttaatgatca gggcatttct ataaaaaata aactattttc tttcctccca 60
gggtcgtcag acaccaaaac atatttctga aagtctagga gctgaggtgg atcct 115
<210>63
<211>120
<212>DNA
<213> Artificial sequence
<400>63
aatactccac tatgtaagac aaaggctggt gctggaactc tggggttctc ccaggctctt 60
acctgtgggc atgttggtga agggcccata gcaacagatt tctagccccc tgaagatctg 120
<210>64
<211>120
<212>DNA
<213> Artificial sequence
<400>64
aatatatctg aaacttctag caataaaact agtagtgcag atacccaaaa agtggccatt 60
attgaactta cagatgggtg gtatgctgtt aaggcccagt tagatcctcc cctcttagct 120
<210>65
<211>121
<212>DNA
<213> Artificial sequence
<400>65
aatatcgtag gtaaaaatgc ctattggatc caaagagagg ccaacatttt ttgaaatttt 60
taagacacgc tgcaacaaag caggtattga caaattttat ataactttat aaattacacc 120
g 121
<210>66
<211>120
<212>DNA
<213> Artificial sequence
<400>66
aatcaaaaat ttgccaaacg aaaattatgg caggttgtta cgaggcattg gatgattcag 60
aggatattct tcataactct ctagataatg atgaatgtag cacgcattca cataaggttt 120
<210>67
<211>120
<212>DNA
<213> Artificial sequence
<400>67
aatctgtaag aaaggtgaaa ttgtagacat caagggaacg ggtactgttc aaaaaggaat 60
gccccacaag tgttaccatg gcaaaactgg aaaagtctac aacgtgaccc agcatgctgt 120
<210>68
<211>118
<212>DNA
<213> Artificial sequence
<400>68
aatgagattc atcagtttaa caaaaacaac tccaatcaag cagtagctgt aactttcaca 60
aagtgtgaag aagaaccttt aggtattgta tgacaatttg tgtgatgaat ttttgcct 118
<210>69
<211>111
<212>DNA
<213> Artificial sequence
<400>69
aatggctgaa ctagaagctg tgttagaaca gcatgggagc cagccttcta acagctaccc 60
ttccatcata agtgactctt ctgcccttga ggacctgcga aatccagaac a 111
<210>70
<211>120
<212>DNA
<213> Artificial sequence
<400>70
aattaaattg ttctttcttt ctttataatt tatagatttt gcatgctgaa acttctcaac 60
cagaagaaag ggccttcaca gtgtccttta tgtaagaatg atataaccaa aaggtatata 120
<210>71
<211>120
<212>DNA
<213> Artificial sequence
<400>71
aattaatttg cactcttggt aaaaatcagt cattgattca gttaaattct agaagtttta 60
catttaaatt ttaaatgctt actaaggatg ctcaatttct tagatgtact gataatttta 120
<210>72
<211>125
<212>DNA
<213> Artificial sequence
<400>72
aattattgag cctcatttat tttctttttc tcccccccta ccctgctagt ctggagttga 60
tcaaggaacc tgtctccaca aagtgtgacc acatattttg caagtaagtt tgaatgtgtt 120
atgtg 125
<210>73
<211>120
<212>DNA
<213> Artificial sequence
<400>73
aattggtatc acatttaggg tttttcattc ttttttggtc caaacttttc atttctgctt 60
ttaaaggaaa tacttttgga aacataaata tgtgggtttg caatttataa agcagctttt 120
<210>74
<211>119
<212>DNA
<213> Artificial sequence
<400>74
aatttaattt caggagccta caagaaagta cgagatttag tcaacttgtt gaagagctat 60
tgaaaatcat ttgtgctttt cagcttgaca caggtttgga gtgtaagtgt tgaatatcc 119
<210>75
<211>120
<212>DNA
<213> Artificial sequence
<400>75
aatttgaagg tacagttgaa attaaacgga agtttgctgg cctgttgaaa aatgactgta 60
acaaaagtgc ttctggttat ttaacagatg aaaatgaagt ggggtttagg ggcttttatt 120
<210>76
<211>120
<212>DNA
<213> Artificial sequence
<400>76
aatttgctaa tagatgccta agcccagaaa gggtgcttct tcaactaaaa tacaggcaag 60
tttaaagcat tacattacgt aatcatatac ggcagtatgg ttaaggtttc tgtgtagtct 120
<210>77
<211>120
<212>DNA
<213> Artificial sequence
<400>77
acaaaagtgc ttctggttat ttaacagatg aaaatgaagt ggggtttagg ggcttttatt 60
ctgctcatgg cacaaaactg aatgtttcta ctgaagctct gcaaaaagct gtgaaactgt 120
<210>78
<211>120
<212>DNA
<213> Artificial sequence
<400>78
acaaaatctc caaggaagtt gtaccgtctt tggcctgtga atggtctcaa ctaacccttt 60
caggtctaaa tggagcccag atggagaaaa tacccctatt gcatatttct tcatgtgacc 120
<210>79
<211>120
<212>DNA
<213> Artificial sequence
<400>79
acaaacaaca gttggtatta ggaaccaaag tgtcacttgt tgagaacatt catgttttgg 60
gaaaagaaca ggcttcacct aaaaacgtaa aaatggaaat tggtaaaact gaaacttttt 120
<210>80
<211>120
<212>DNA
<213> Artificial sequence
<400>80
acaattatga atctgatgtt gaattaacca aaaatattcc catggaaaag aatcaagatg 60
tatgtgcttt aaatgaaaat tataaaaacg ttgagctgtt gccacctgaa aaatacatga 120
<210>81
<211>118
<212>DNA
<213> Artificial sequence
<400>81
acacaaatca gtccccttat tcagtcattg aaaattcagc cttagctttt tacacaagtt 60
gtagtagaaa aacttctgtg agtcagactt cattacttga agcaaaaaaa tggcttag 118
<210>82
<211>120
<212>DNA
<213> Artificial sequence
<400>82
acaccttttt ctgatgtgct ttgttctgga tttcgcaggt cctcaagggc agaagagtca 60
cttatgatgg aagggtagct gttagaaggc tggctcccat gctgttctaa cacagcttct 120
<210>83
<211>120
<212>DNA
<213> Artificial sequence
<400>83
acactcttgt gctgacttac cagatgggac actctaagat tttctgcata gcattaatga 60
cattttgtac ttcttcaacg cgaagagcag ataaatccat ttctttctgt tccaatgaac 120
<210>84
<211>120
<212>DNA
<213> Artificial sequence
<400>84
acagtactat agctgaaaat gacaaaaatc atctctccga aaaacaagat acttatttaa 60
gtaacagtag catgtctaac agctattcct accattctga tgaggtatat aatgattcag 120
<210>85
<211>115
<212>DNA
<213> Artificial sequence
<400>85
acagtgcagt gaattggaag acttgactgc aaatacaaac acccaggatc ctttcttgat 60
tggttcttcc aaacaaatga ggcatcagtc tgaaagccag ggagttggtc tgagt 115
<210>86
<211>120
<212>DNA
<213> Artificial sequence
<400>86
acatgagtag tctcttcagt aattagatta gttaaagtga tgtggtgttt tctggcaaac 60
ttgtacacga gcatctgaaa ttaaatcaaa tattccatta tcatgagtta cctctagcac 120
<210>87
<211>120
<212>DNA
<213> Artificial sequence
<400>87
accacattgg aaagtcaatg ccaaatgtcc tagaagatga agtatatgaa acagttgtag 60
atacctctga agaagatagt ttttcattat gtttttctaa atgtagaaca aaaaatctac 120
<210>88
<211>127
<212>DNA
<213> Artificial sequence
<400>88
accagaactt tgtaattcaa cattcatcgt tgtgtaaatt aaacttctcc cattcctttc 60
agagggaacc ccttacctgg aatctggaat cagcctcttc tctgatgacc ctgaatctga 120
tccttct 127
<210>89
<211>121
<212>DNA
<213> Artificial sequence
<400>89
acccatgcct gagagaaagg tccttgcccg aaggcagatt ttcgccaagc aaattcgagc 60
cccgcccctt ccctgggtct ccatttcccg cctccggccc ggcctttggg ctccgccttc 120
a 121
<210>90
<211>110
<212>DNA
<213> Artificial sequence
<400>90
accgtgtgga agttgcgtat tgtaagctat tcaaaaaaag aaaaagattc aggtaagtat 60
gtaaatgctt tgtttttatc agttttatta acttaaaaaa tgaccttact 110
<210>91
<211>120
<212>DNA
<213> Artificial sequence
<400>91
acctaaaata aaagttaaaa tatttttaaa aagagagaaa catcaatcct taatattaac 60
taaataggaa aataccagct tcatagacaa aggttctctt tgactcacct gcaataagtt 120
<210>92
<211>120
<212>DNA
<213> Artificial sequence
<400>92
acctagtcat gatttctaga ggcaaagaat catacaaaat gtcagacaag ctcaaaggta 60
acaattatga atctgatgtt gaattaacca aaaatattcc catggaaaag aatcaagatg 120
<210>93
<211>120
<212>DNA
<213> Artificial sequence
<400>93
acctgtgggc atgttggtga agggcccata gcaacagatt tctagccccc tgaagatctg 60
gaagaagaga ggaagagaga gggacagggg aatggagaga aggaaaatct agttataaaa 120
<210>94
<211>121
<212>DNA
<213> Artificial sequence
<400>94
accttgtgat gttagtttgg aaacttcaga tatatgtaaa tgtagtatag ggaagcttca 60
taagtcagtc tcatctgcaa atacttgtgg gatttttagc acagcaagtg gaaaatctgt 120
c 121
<210>95
<211>118
<212>DNA
<213> Artificial sequence
<400>95
acgaaactgg actcattact ccaaataaac atggactttt acaaaaccca tatcgtatac 60
caccactttt tcccatcaag tcatttgtta aaactaaatg taagaaaaat ctgctaga 118
<210>96
<211>120
<212>DNA
<213> Artificial sequence
<400>96
acgagatact ttcctgagtg ccataatcag taccaggtac caatgaaata ctgctactct 60
ctacagatct ttcagtttgc aaaacccttt ctccacttaa catgagatct ttggggtctt 120
<210>97
<211>115
<212>DNA
<213> Artificial sequence
<400>97
acgtatttct agcctaccaa aatcagagaa gccattaaat gaggaaacag tggtaaataa 60
gagagatgaa gagcagcatc ttgaatctca tacagactgc attcttgcag taaag 115
<210>98
<211>120
<212>DNA
<213> Artificial sequence
<400>98
actaaggaac gtcaagagat acagaatcca aattttaccg cacctggtca agaatttctg 60
tctaaatctc atttgtatga acatctgact ttggaaaaat cttcaagcaa tttagcagtt 120
<210>99
<211>111
<212>DNA
<213> Artificial sequence
<400>99
actaaggaac ttcatgaaac agacttgact tgtgtaaacg aacccatttt caagaactct 60
accatggttt tatatggaga cacaggtgat aaacaagcaa cccaagtgtc a 111
<210>100
<211>120
<212>DNA
<213> Artificial sequence
<400>100
actacaggca gaccaaccaa agtctttgtt ccacctttta aaactaaatc acattttcac 60
agagttgaac agtgtgttag gaatattaac ttggaggaaa acagacaaaa gcaaaacatt 120
<210>101
<211>120
<212>DNA
<213> Artificial sequence
<400>101
actactttga aacagaagca gtagaaattg ctaaagcttt tatggaagat gatgaactga 60
cagattctaa actgccaagt catgccacac attctctttt tacatgtccc gaaaatgagg 120
<210>102
<211>120
<212>DNA
<213> Artificial sequence
<400>102
actcagcatc tgcagaatga aaaacactca aaggattaga agttgaaaac aaaatcagga 60
agtgctgtcc taagaagcta aagagcctca gttttttaca ctcccaagat caatctggat 120
<210>103
<211>120
<212>DNA
<213> Artificial sequence
<400>103
actcattaac tttctgaatg ctgctattta gtgttatcca aggaacatct tcagtatctc 60
taggattctc tgagcatggc agtttctgct tattccattc ttttctctca cacaggggat 120
<210>104
<211>119
<212>DNA
<213> Artificial sequence
<400>104
actccaataa tattcaaaga gcaagggctg actctgccgc tgtaccaatc tcctgtaaaa 60
gaattagata aattcaaatt agacttaggt aagtaatgca atatggtaga ctggggaga 119
<210>105
<211>120
<212>DNA
<213> Artificial sequence
<400>105
actgactcac acatttattt ggttctgttt ttgccttccc tagagtgcta acttccagta 60
acgagatact ttcctgagtg ccataatcag taccaggtac caatgaaata ctgctactct 120
<210>106
<211>121
<212>DNA
<213> Artificial sequence
<400>106
actgttcagc ccagtttgaa gcaaatgctt ttgaagcacc acttacattt gcaaatgctg 60
attcaggtac ctctgtcttt ttttttttgt aaatagtaca tatagtttta tagatgacga 120
t 121
<210>107
<211>94
<212>DNA
<213> Artificial sequence
<400>107
actttaacag gatttggaaa aacatcaggg aattcattta aagtaaatag ctgcaaagac 60
cacattggaa agtcaatgcc aaatgtccta gaag 94
<210>108
<211>121
<212>DNA
<213> Artificial sequence
<400>108
acttttattg atttattttt tggggggaaa ttttttagga tctgattctt ctgaagatac 60
cgttaataag gcaacttatt gcaggtgagt caaagagaac ctttgtctat gaagctggta 120
t 121
<210>109
<211>122
<212>DNA
<213> Artificial sequence
<400>109
agaaagaata aatactgcag attatgtagg aaattatttg tatgaaaata attcaaacag 60
tactatagct gaaaatgaca aaaatcatct ctccgaaaaa caagatactt atttaagtaa 120
ca 122
<210>110
<211>120
<212>DNA
<213> Artificial sequence
<400>110
agaaagtaat tgtgcaaact tcctgagttt tcatggacag cacttgagtg tcattcttgg 60
gatattcaac acttacactc caaacctgtg tcaagctgaa aagcacaaat gattttcaat 120
<210>111
<211>120
<212>DNA
<213> Artificial sequence
<400>111
agaaatctgt attaacagtc tgaactactt cttcatattc ttgctttttt atttcaggat 60
gcttacaatt acttccagga agactttgtt tatagacctc aggttgcaaa acccctaatc 120
<210>112
<211>115
<212>DNA
<213> Artificial sequence
<400>112
agaacttttc tcagacaatg agaataattt tgtcttccaa gtagctaatg aaaggaataa 60
tcttgcttta ggaaatacta aggaacttca tgaaacagac ttgacttgtg taaac 115
<210>113
<211>120
<212>DNA
<213> Artificial sequence
<400>113
agaagcagtt cctttaacta tacttggaaa tttgtaaaat gtgctcccca aaagcataaa 60
catttagctc acttctataa atagactggg gcaaacacaa aaacctggtt ccaataccta 120
<210>114
<211>120
<212>DNA
<213> Artificial sequence
<400>114
agaaggatca gattcagggt catcagagaa gaggctgatt ccagattcca ggtaaggggt60
tccctctgaa aggaatggga gaagtttaat ttacacaacg atgaatgttg aattacaaag 120
<210>115
<211>120
<212>DNA
<213> Artificial sequence
<400>115
agaatagcct ctagaacatt tcagcaatct gaggaacccc catcgtggga tcttgcttat 60
aatactccac tatgtaagac aaaggctggt gctggaactc tggggttctc ccaggctctt 120
<210>116
<211>120
<212>DNA
<213> Artificial sequence
<400>116
agaattcagc cttttctaca ttcattctgt ctttagtgag taataaactg ctgttctcat 60
gctgtaatga gctggcatga gtatttgtgc cacatggctc cacatgcaag tttgaaacag 120
<210>117
<211>115
<212>DNA
<213> Artificial sequence
<400>117
agacaagtgt tttctgaaat agaagatagt accaagcaag tcttttccaa agtattgttt 60
aaaagtaacg aacattcaga ccagctcaca agagaagaaa atactgctat acgta 115
<210>118
<211>112
<212>DNA
<213> Artificial sequence
<400>118
agaccacatt ggaaagtcaa tgccaaatgt cctagaagat gaagtatatg aaacagttgt 60
agatacctct gaagaagata gtttttcatt atgtttttct aaatgtagaa ca 112
<210>119
<211>120
<212>DNA
<213> Artificial sequence
<400>119
agaccattga gatcacagct gccccaaagt gtaaagaaat gcagaattct ctcaataatg 60
ataaaaacct tgtttctatt gagactgtgg tgccacctaa gctcttaagt gataatttat 120
<210>120
<211>120
<212>DNA
<213> Artificial sequence
<400>120
agacttttga gaaataaaac tgatattatt tgccttaaaa acatatatga aatatttctt 60
tttaggagaa ccctcaatca aaagaaactt attaaatgaa tttgacagga taatagaaaa 120
<210>121
<211>109
<212>DNA
<213> Artificial sequence
<400>121
agagaaatgg gaaatgagaa cattccaagt acagtgagca caattagccg taataacatt 60
agagaaaatg tttttaaaga agccagctca agcaatatta atgaagtag 109
<210>122
<211>119
<212>DNA
<213> Artificial sequence
<400>122
agagcagcatcttgaatctc atacagactg cattcttgca gtaaagcagg caatatctgg 60
aacttctcca gtggcttctt catttcaggg tatcaaaaag tctatattca gaataagag 119
<210>123
<211>120
<212>DNA
<213> Artificial sequence
<400>123
agagttctca cagttccaag gttagagagt tggacactga gactggtttc ctgctaaaca 60
gtatggtaaa gaacagtcaa gcaattgttg gccagttctg tgcttttcct cctgaagaga 120
<210>124
<211>120
<212>DNA
<213> Artificial sequence
<400>124
agagttgaac agtgtgttag gaatattaac ttggaggaaa acagacaaaa gcaaaacatt 60
gatggacatg gctctgatga tagtaaaaat aagattaatg acaatgagat tcatcagttt 120
<210>125
<211>105
<212>DNA
<213> Artificial sequence
<400>125
agataataga aatgacacag aaggctttaa gtatccattg ggacatgaag ttaaccacag 60
tcgggaaaca agcatagaaa tggaagaaag tgaacttgat gctca 105
<210>126
<211>108
<212>DNA
<213> Artificial sequence
<400>126
agatagtttt tcattatgtt tttctaaatg tagaacaaaa aatctacaaa aagtaagaac 60
tagcaagact aggaaaaaaa ttttccatga agcaaacgct gatgaatg 108
<210>127
<211>120
<212>DNA
<213> Artificial sequence
<400>127
agatatgata cggaaattga tagaagcaga agatcggcta taaaaaagat aatggaaagg 60
gatgacacag ctgcaaaaac acttgttctc tgtgtttctg acataatttc attgagcgca 120
<210>128
<211>120
<212>DNA
<213> Artificial sequence
<400>128
agatgagctc taattttgtt gtatttgtcc tgtttaaagc catctagtta caatagatgg 60
aacttttttg ttctgattgc tttttattcc aatatcttaa atggtcacag ggttatttca 120
<210>129
<211>120
<212>DNA
<213> Artificial sequence
<400>129
agattgatga ccaaaagaac tgcaaaaaga gaagagcctt ggatttcttg agtagactgc 60
ctttacctcc acctgttagt cccatttgta catttgtttc tccggctgca cagaaggcat 120
<210>130
<211>120
<212>DNA
<213> Artificial sequence
<400>130
agattttgtg ggttgtaaag gtcccaaatg gtcttcagaa taatctaatt acagtactgt 60
atctacccac tctcttttca gtgcctgtta agttggcaaa ctttgccatt accctttttt 120
<210>131
<211>115
<212>DNA
<213> Artificial sequence
<400>131
agcaaaagcg tccagaaagg agagcttagc aggagtccta gccctttcac ccatacacat 60
ttggctcagg gttaccgaag aggggccaag aaattagagt cctcagaaga gaact 115
<210>132
<211>120
<212>DNA
<213> Artificial sequence
<400>132
agcacaacat atgtcttaaa ttatctggcc agtttatgaa ggagggaaac actcagatta 60
aagaagattt gtcagattta acttttttgg aagttgcgaa agctcaagaa gcatgtcatg 120
<210>133
<211>120
<212>DNA
<213> Artificial sequence
<400>133
agcatataaa aatgactcta ggtcaagatt taaaatcgga catctccttg aatatagata 60
aaataccaga aaaaaataat gattacatga acaaatgggc aggactctta ggtccaattt 120
<210>134
<211>120
<212>DNA
<213> Artificial sequence
<400>134
agcattctgc ctcatacagg caattcagta aacgttaagt gaaataaaga gtgaatgaaa 60
aaataatatc cttaatgatc agggcatttc tataaaaaat aaactatttt ctttcctccc 120
<210>135
<211>120
<212>DNA
<213> Artificial sequence
<400>135
agccacggga gccccttcac ttcagcaaat ttttagatcc agactttcag ccatcttgtt 60
ctgaggtgga cctaatagga tttgtcgttt ctgttgtgaa aaaaacaggt aatgcacaat 120
<210>136
<211>119
<212>DNA
<213> Artificial sequence
<400>136
agccattaaa ttgtccatat ctaatagtaa taattttgag gtagggccac ctgcatttag 60
gatagccagt ggtaaaatcg tttgtgtttc acatgaaaca attaaaaaag tgaaagaca 119
<210>137
<211>120
<212>DNA
<213> Artificial sequence
<400>137
agcctcagtc aattaatact gtatctgcac atttacagag tagtgtagtt gtttctgatt 60
gtaaaaatag tcatataacc cctcagatgt tattttccaa gcaggatttt aattcaaacc 120
<210>138
<211>120
<212>DNA
<213> Artificial sequence
<400>138
agctcttcaa caagttgact aaatctcgta ctttcttgta ggctcctgaa attaaattgt 60
ttgagaaaca cactcagcaa gtgattatca accttttaag gacactaaaa taagaaaaga 120
<210>139
<211>114
<212>DNA
<213> Artificial sequence
<400>139
agctggacac ctacctgata ccccagatcc cccacagcca ctactgactg cagccagcca 60
caggtacaga gccacaggac cccaagaatg agcttacaaa gtggcctttc cagg 114
<210>140
<211>120
<212>DNA
<213> Artificial sequence
<400>140
aggaaacaga catagttaaa cacaaaatac tgaaagaaag tgtcccagtt ggtactggaa 60
atcaactagt gaccttccag ggacaacccg aacgtgatga aaagatcaaa gaacctactc 120
<210>141
<211>120
<212>DNA
<213> Artificial sequence
<400>141
aggaaacagt ggtaaataag agagatgaag agcagcatct tgaatctcat acagactgca 60
ttcttgcagt aaagcaggca atatctggaa cttctccagt ggcttcttca tttcagggta 120
<210>142
<211>111
<212>DNA
<213> Artificial sequence
<400>142
aggaatcttt ggacaaagtg aaaaaccttt ttgatgaaaa agagcaaggt actagtgaaa 60
tcaccagttt tagccatcaa tgggcaaaga ccctaaagta cagagaggcc t 111
<210>143
<211>120
<212>DNA
<213> Artificial sequence
<400>143
aggaatttga tttaatcaga actgagcata gtcttcacta ttcacctacg tctagacaaa 60
atgtatcaaa aatacttcct cgtgttgata agagaaaccc agagcactgt gtaaactcag 120
<210>144
<211>115
<212>DNA
<213> Artificial sequence
<400>144
aggagaacaa aaatagtgta aagcagcata taaaaatgac tctaggtcaa gatttaaaat 60
cggacatctc cttgaatata gataaaatac cagaaaaaaa taatgattac atgaa 115
<210>145
<211>120
<212>DNA
<213> Artificial sequence
<400>145
aggatattct tcataactct ctagataatg atgaatgtag cacgcattca cataaggttt 60
ttgctgacat tcagagtgaa gaaattttac aacataacca aaatatgtct ggattggaga 120
<210>146
<211>120
<212>DNA
<213> Artificial sequence
<400>146
aggattcaga gtaaaatcaa agtgtttgtt ccaatacagc agatgaaata ttacctagat 60
cttgccttgg caagtaagat gtttccgtca aatcgtgtgg cccagactct tccagctgtt 120
<210>147
<211>120
<212>DNA
<213> Artificial sequence
<400>147
aggcatgagc cactgtgccc aaacactacc tttttaactt agtgaaaaat atttagtgaa 60
tgtgattgat ggtactttaa ttttgtcact ttgtgttttt atgtttaggt ttattgcatt 120
<210>148
<211>120
<212>DNA
<213> Artificial sequence
<400>148
aggccagtac ggaagaatgt gagaaaaata agcaggacac aattacaact aaaaaatata 60
tctaagcatt tgcaaaggcg acaataaatt attgacgctt aacctttcca gtttataaga 120
<210>149
<211>120
<212>DNA
<213> Artificial sequence
<400>149
agggaagctc ttcatcctca ctagataagt tctcttctga ggactctaat ttcttggccc 60
ctcttcggta accctgagcc aaatgtgtat gggtgaaagg gctaggactc ctgctaagct 120
<210>150
<211>120
<212>DNA
<213> Artificial sequence
<400>150
agggagactg tgtgtaatat ttgcgtgctt aaatattttc aatgaaaagt tactttgatt 60
tagtttttta tgttactaca taattatgat aggctacgtt ttcatttttt tatcagatgt 120
<210>151
<211>120
<212>DNA
<213> Artificial sequence
<400>151
agggtcgtca gacaccaaaa catatttctg aaagtctagg agctgaggtg gatcctgata 60
tgtcttggtc aagttcttta gctacaccac ccacccttag ttctactgtg ctcataggta 120
<210>152
<211>120
<212>DNA
<213> Artificial sequence
<400>152
agggtgaatg atgaaagctc cttcaccaca gaagcaccac acagctgtac catccattcc 60
agttgatcta aaatggacat ttagatgtaa aatcactgca gtaatctgca tacttaaccc 120
<210>153
<211>120
<212>DNA
<213> Artificial sequence
<400>153
aggttttccc aaatattttg tcttcaatat tactctctac tgatttggag tgaactcttt 60
cacttttaca tattaaagcc tcatgaggat cactggccag taagtctatt ttctctgaag 120
<210>154
<211>120
<212>DNA
<213> Artificial sequence
<400>154
agtagtatga gcagcagctg gactctgggc agattctgca actttcaatt ggggaacttt 60
caatgcagag gttgaagatg gtatgttgcc aacacgagct gactctgggg ctctgtcttc 120
<210>155
<211>120
<212>DNA
<213> Artificial sequence
<400>155
agtagtggct gtgggggatc tggggtatca ggtaggtgtc cagctcctgg cactggtaga 60
gtgctacact gtccaacacc cactctcggg tcaccacagg tgcctcacac atctgcccaa 120
<210>156
<211>107
<212>DNA
<213> Artificial sequence
<400>156
agtcatttaa taaaattgta aatttctttg atcagaaacc agaagaattg cataactttt 60
ccttaaattc tgaattacat tctgacataa gaaagaacaa aatggac 107
<210>157
<211>120
<212>DNA
<213> Artificial sequence
<400>157
agtcatttaa taaaattgta aatttctttg atcagaaacc agaagaattg cataactttt 60
ccttaaattc tgaattacat tctgacataa gaaagaacaa aatggacatt ctaagttatg 120
<210>158
<211>120
<212>DNA
<213> Artificial sequence
<400>158
agtctgtttc cacacctgtc tcagcccaga tgacttcaaa gtcttgtaaa ggggagaaag 60
agattgatga ccaaaagaac tgcaaaaaga gaagagcctt ggatttcttg agtagactgc 120
<210>159
<211>120
<212>DNA
<213> Artificial sequence
<400>159
agttaagaaa atcagcaatt acaatagcct aatcttacta gacatgtctt ttcttcccta 60
gtatgtaagg tcaattctgt tcatttgcat aggagataat cataggaatc ccaaattaat 120
<210>160
<211>120
<212>DNA
<213> Artificial sequence
<400>160
agttatatag tttcttatct ttaaatctcc cttctttggg tgttttatgc ttggttcttt 60
agttttagtt gcttttgaat ttacagttta gtgaattaat aatccttttg ttttcttaga 120
<210>161
<211>120
<212>DNA
<213> Artificial sequence
<400>161
agttcagcca tttcctgctg gagctttatc aggttatgtt gcatggtatc cctctgcttc 60
aaaaacgata aatggcacca agaaaatgaa atactttgag aagctttcca ttaaatgaaa 120
<210>162
<211>120
<212>DNA
<213> Artificial sequence
<400>162
agttgatcta aaatggacat ttagatgtaa aatcactgca gtaatctgca tacttaaccc 60
aggccctcta ccctacactc tccggatgaa ggcttatagc aagacctctc aatgggagag 120
<210>163
<211>120
<212>DNA
<213> Artificial sequence
<400>163
agttgttgaa ttcagtatca tcctatgtgg tttttatgat aatattctac ttttatttgt 60
tcagggctct gtgtgacact ccaggtgtgg atccaaagct tatttctaga atttgggttt 120
<210>164
<211>120
<212>DNA
<213> Artificial sequence
<400>164
agtttcacac tgaagattat tttggtaagg aaagtttatg gactggaaaa ggaatacagt 60
tggctgatgg tggatggctc ataccctcca atgatggaaa ggctggaaaa gaagaatttt 120
<210>165
<211>120
<212>DNA
<213> Artificial sequence
<400>165
agtttgaatc catgctttgc tcttcttgat tattttcttc caagcccgtt cctctttctt 60
catcatctga aaccaattcc ttgtcactca gaccaactcc ctggctttca gactgatgcc 120
<210>166
<211>120
<212>DNA
<213> Artificial sequence
<400>166
agttttagtt gcttttgaat ttacagttta gtgaattaat aatccttttg ttttcttaga 60
aaacacaaca aaaccatatt taccatcacg tgcactaaca agacagcaag ttcgtgcttt 120
<210>167
<211>120
<212>DNA
<213> Artificial sequence
<400>167
ataaaaacct tgtttctatt gagactgtgg tgccacctaa gctcttaagt gataatttat 60
gtagacaaac tgaaaatctc aaaacatcaa aaagtatctt tttgaaagtt aaagtacatg 120
<210>168
<211>113
<212>DNA
<213> Artificial sequence
<400>168
ataaaaatta acagcaaaaa tgcagagtct tttcagtttc acactgaaga ttattttggt 60
aaggaaagtt tatggactgg aaaaggaata cagttggctg atggtggatg gct 113
<210>169
<211>120
<212>DNA
<213> Artificial sequence
<400>169
ataaaagatc gaagattgtt tatgcatcat gtttctttag agccgattac ctgtgtaccc 60
tttcggtaag acatgtttaa atttttctaa attctaatac agtatgagaa aagtctcgtt 120
<210>170
<211>120
<212>DNA
<213> Artificial sequence
<400>170
ataacaaata tactgctgcc agtagaaatt ctcataactt agaatttgat ggcagtgatt 60
caagtaaaaa tgatactgtt tgtattcata aagatgaaac ggacttgcta tttactgatc 120
<210>171
<211>120
<212>DNA
<213> Artificial sequence
<400>171
ataatagcaa atgtgtattt acaagaaaga gcagatgagg ttgataattg tcatctctaa 60
tacttctgtt aaaaggaaat atgaaaagaa aatattagat aatgtctttg ataagtgtgt 120
<210>172
<211>120
<212>DNA
<213> Artificial sequence
<400>172
ataatcacta tagatggatc atatggaaac tggcagctat ggaatgtgcc tttcctaagg 60
aatttgctaa tagatgccta agcccagaaa gggtgcttct tcaactaaaa tacaggcaag 120
<210>173
<211>120
<212>DNA
<213> Artificial sequence
<400>173
ataatttaac acctagccaa aaggcagaaa ttacagaact ttctactata ttagaagaat 60
caggaagtca gtttgaattt actcagttta gaaaaccaag ctacatattg cagaagagta 120
<210>174
<211>120
<212>DNA
<213> Artificial sequence
<400>174
atacctctga agaagatagt ttttcattat gtttttctaa atgtagaaca aaaaatctac 60
aaaaagtaag aactagcaag actaggaaaa aaattttcca tgaagcaaac gctgatgaat 120
<210>175
<211>120
<212>DNA
<213> Artificial sequence
<400>175
atacgtatgg cgtttctaaa cattgcataa aaattaacag caaaaatgca gagtcttttc 60
agtttcacac tgaagattat tttggtaagg aaagtttatg gactggaaaa ggaatacagt 120
<210>176
<211>120
<212>DNA
<213> Artificial sequence
<400>176
atactttaac aggatttgga aaaacatcag ggaattcatt taaagtaaat agctgcaaag 60
accacattgg aaagtcaatg ccaaatgtcc tagaagatga agtatatgaa acagttgtag 120
<210>177
<211>120
<212>DNA
<213> Artificial sequence
<400>177
atagacctta atgaggacat tattaagcct catatgttaa ttgctgcaag caacctccag 60
tggcgaccag aatccaaatc aggccttctt actttatttg ctggagattt ttctgtgttt 120
<210>178
<211>120
<212>DNA
<213> Artificial sequence
<400>178
atagattaca gatacagaac taaaattaac ctagactaaa aggtcttatc accacgtcat 60
agaaagtaat tgtgcaaact tcctgagttt tcatggacag cacttgagtg tcattcttgg 120
<210>179
<211>120
<212>DNA
<213> Artificial sequence
<400>179
ataggtactc tatgcaaaaa gattgtgtgt taacttttat gtattccctc atccctcttt 60
cttctcttaa ctgtctctcg aactaaaaag ttggctagaa atcaaatttt tatgcattta 120
<210>180
<211>120
<212>DNA
<213> Artificial sequence
<400>180
atagttaatt ttttttattg attcttttaa aaaacattgt cttttaaaat ctcttatgat 60
tagttggagc taccagttgg caaatttgct agctaactag tgatctgaaa gtaagcctct 120
<210>181
<211>120
<212>DNA
<213> Artificial sequence
<400>181
atatatgttc tctaggcctt ttagaaaaca tggagttgtt cctttggcca tgtatatgcg 60
aatctgtaag aaaggtgaaa ttgtagacat caagggaacg ggtactgttc aaaaaggaat 120
<210>182
<211>120
<212>DNA
<213> Artificial sequence
<400>182
atatcattct tacataaagg acactgtgaa ggccctttct tctggttgag aagtttcagc 60
atgcaaaatc tataaattat aaagaaagaa agaacaattt aatttacttc cttttgtaga 120
<210>183
<211>119
<212>DNA
<213> Artificial sequence
<400>183
atatggaaac tggcagctat ggaatgtgcc tttcctaagg aatttgctaa tagatgccta 60
agcccagaaa gggtgcttct tcaactaaaa tacaggcaag tttaaagcat tacattacg 119
<210>184
<211>120
<212>DNA
<213> Artificial sequence
<400>184
atatggtaca cattgttatt tctaatatga gaacaaagtc ttagagactt tgaatttaac 60
atttttaatg agtaaattgt ttttattttg agtagtaaat tgactttatt ttttagtatc 120
<210>185
<211>117
<212>DNA
<213> Artificial sequence
<400>185
atattacaaa ataatattga aatgactact ggcacttttg ttgaagaaat tactgaaaat 60
tacaagagaa atactgaaaa tgaagataac aaatatactg ctgccagtag aaattct 117
<210>186
<211>120
<212>DNA
<213> Artificial sequence
<400>186
atcaaaaaaa cactagtttt tccaaagtaa tatccaatgt aaaagatgca aatgcatacc 60
cacaaactgt aaatgaagat atttgcgttg aggaacttgt gactagctct tcaccctgca 120
<210>187
<211>120
<212>DNA
<213> Artificial sequence
<400>187
atcaactagt gaccttccag ggacaacccg aacgtgatga aaagatcaaa gaacctactc 60
tattgggttt tcatacagct agcgggaaaa aagttaaaat tgcaaaggaa tctttggaca 120
<210>188
<211>120
<212>DNA
<213> Artificial sequence
<400>188
atcaatgggc aaagacccta aagtacagag aggcctgtaa agaccttgaa ttagcatgtg 60
agaccattga gatcacagct gccccaaagt gtaaagaaat gcagaattct ctcaataatg 120
<210>189
<211>120
<212>DNA
<213> Artificial sequence
<400>189
atcagagaag caaaatccac tactaatgcc cacaaagaga taatataaaa gaggatctgt 60
atttattttg aaacaaacat ttaaatgata atcacttctt ccattgcatc tttctcatct 120
<210>190
<211>102
<212>DNA
<213> Artificial sequence
<400>190
atcaggcctt catcctgagg attttatcaa gaaagcagat ttggcagttc aaaagactcc 60
tgaaatgata aatcagggaa ctaaccaaac ggagcagaat gg 102
<210>191
<211>120
<212>DNA
<213> Artificial sequence
<400>191
atctacccac tctcttttca gtgcctgtta agttggcaaa ctttgccatt accctttttt 60
gcagaatcca aactgatttc atccctggtt ccttgagggg tgatttgtaa caattcttga 120
<210>192
<211>118
<212>DNA
<213> Artificial sequence
<400>192
atctggaatc agcctcttct ctgatgaccc tgaatctgat ccttctgaag acagagcccc 60
agagtcagct cgtgttggca acataccatc ttcaacctct gcattgaaag ttccccaa 118
<210>193
<211>122
<212>DNA
<213> Artificial sequence
<400>193
atcttgggag tgtaaaaaac tgaggctctt tagcttctta ggacagcact tcctgatttt 60
gttttcaact tctaatcctt tgagtgtttt tcattctgca gatgctgagt ttgtgtgtga 120
ac 122
<210>194
<211>99
<212>DNA
<213> Artificial sequence
<400>194
atgaaagaga ggaagaaaag gaagcagcaa aatatgtgga ggcccaacaa aagagactag 60
aagccttatt cactaaaatt caggaggaat ttgaagaac 99
<210>195
<211>111
<212>DNA
<213> Artificial sequence
<400>195
atgaaatagg ttccagtgat gaaaacattc aagcagaact aggtagaaac agagggccaa 60
aattgaatgc tatgcttaga ttaggggttt tgcaacctga ggtctataaa c 111
<210>196
<211>120
<212>DNA
<213> Artificial sequence
<400>196
atgaactcat aaaaacttaa tgatcttgaa caatgtagtt tttgtacaga gaatagttgt 60
agttgttgaa ttcagtatca tcctatgtgg tttttatgat aatattctac ttttatttgt 120
<210>197
<211>120
<212>DNA
<213> Artificial sequence
<400>197
atgaagctat tatattaaaa tatttaaatg aaacattttc ctacatatat ttgttctata 60
aagatgaatc tgatttttat gctaatattt tggctaagag cctggtagaa gatcttacat 120
<210>198
<211>120
<212>DNA
<213> Artificial sequence
<400>198
atgacctaga aagataaatg gaaggagaaa accatcgcca ccaattgtga aaggacaaat 60
catacttgct gggcagccaa agcataaatg aaacagctca tgtcagagag atcagaaatg 120
<210>199
<211>120
<212>DNA
<213> Artificial sequence
<400>199
atgatactga tccattagat tcaaatgtag caaatcagaa gccctttgag agtggaagtg 60
acaaaatctc caaggaagtt gtaccgtctt tggcctgtga atggtctcaa ctaacccttt 120
<210>200
<211>120
<212>DNA
<213> Artificial sequence
<400>200
atgatcatga aaatgccagc actcttattt taactcctac ttccaaggat gttctgtcaa 60
acctagtcat gatttctaga ggcaaagaat catacaaaat gtcagacaag ctcaaaggta 120
<210>201
<211>120
<212>DNA
<213> Artificial sequence
<400>201
atgcaaaatc tataaattat aaagaaagaa agaacaattt aatttacttc cttttgtaga 60
aagaatactc aaaaggcaaa tagccatgaa aagataatct cacaactgcc cttaagagcc 120
<210>202
<211>106
<212>DNA
<213> Artificial sequence
<400>202
atgccatggt ggaataacta gtattctgag ctgtgtgcta gaggtaactc atgataatgg 60
aatatttgat ttaatttcag atgctcgtgt acaagtttgc cagaaa 106
<210>203
<211>120
<212>DNA
<213> Artificial sequence
<400>203
atgcgccacc gtgcctcgcc tcatgtggtt ttatgcagca gatgcaaggt attctgtaaa 60
ggttcttggt atacctgttt tcataacaac atgagtagtc tcttcagtaa ttagattagt 120
<210>204
<211>115
<212>DNA
<213> Artificial sequence
<400>204
atgctataca tgatgaaaca tcttataaag gaaaaaaaat accgaaagac caaaaatcag 60
aactaattaa ctgttcagcc cagtttgaag caaatgcttt tgaagcacca cttac 115
<210>205
<211>120
<212>DNA
<213> Artificial sequence
<400>205
atgctgatct tcatgtcata atgaatgccc catcgattgg tcaggtagac agcagcaagc 60
aatttgaagg tacagttgaa attaaacgga agtttgctgg cctgttgaaa aatgactgta 120
<210>206
<211>120
<212>DNA
<213> Artificial sequence
<400>206
atggataagg ggggactact actatatgtg cattgagagt ttttatacta gtgattttaa 60
actataattt ttgcagaatg tgaaaagcta tttttccaat catgatgaaa gtctgaagaa 120
<210>207
<211>120
<212>DNA
<213> Artificial sequence
<400>207
atggatattc tcttagattt taactaatat gtaatataaa ataattgttt cctaggcaca 60
ataaaagatc gaagattgtt tatgcatcat gtttctttag agccgattac ctgtgtaccc 120
<210>208
<211>120
<212>DNA
<213> Artificial sequence
<400>208
atgtatcaaa aatacttcct cgtgttgata agagaaaccc agagcactgt gtaaactcag 60
aaatggaaaa aacctgcagt aaagaattta aattatcaaa taacttaaat gttgaaggtg 120
<210>209
<211>120
<212>DNA
<213> Artificial sequence
<400>209
atgttgaatt tttgttttgt tttctgtagg tttcagatga aattttattt cagatttacc 60
agccacggga gccccttcac ttcagcaaat ttttagatcc agactttcag ccatcttgtt 120
<210>210
<211>120
<212>DNA
<213> Artificial sequence
<400>210
atgttgcaca ttcctcttct gcatttcctg gatttgaaaa cggagcaaat gactggcgct 60
ttgaaacctt gaatgtattc tgcaaatact gagcatcaag ttcactttct tccatttcta 120
<210>211
<211>118
<212>DNA
<213> Artificial sequence
<400>211
attacgaacc aaacctattt aaaactccac aaaggaaacc atcttataat cagctggctt 60
caactccaat aatattcaaa gagcaagggc tgactctgcc gctgtaccaa tctcctgt 118
<210>212
<211>117
<212>DNA
<213> Artificial sequence
<400>212
attaggaacc aaagtgtcac ttgttgagaa cattcatgtt ttgggaaaag aacaggcttc 60
acctaaaaac gtaaaaatgg aaattggtaa aactgaaact ttttctgatg ttcctgt 117
<210>213
<211>120
<212>DNA
<213> Artificial sequence
<400>213
attatctcag actgaaacga cgttgtacta catctctgat caaagaacag gagagttccc 60
aggccagtac ggaagaatgt gagaaaaata agcaggacac aattacaact aaaaaatata 120
<210>214
<211>120
<212>DNA
<213> Artificial sequence
<400>214
attcagacca gctcacaaga gaagaaaata ctgctatacg tactccagaa catttaatat 60
cccaaaaagg cttttcatat aatgtggtaa attcatctgc tttctctgga tttagtacag 120
<210>215
<211>120
<212>DNA
<213> Artificial sequence
<400>215
attcagactc cccatcatgt gagtcatcag aacctaacag ttcatcactt ctggaaaacc 60
actcattaac tttctgaatg ctgctattta gtgttatcca aggaacatct tcagtatctc 120
<210>216
<211>117
<212>DNA
<213> Artificial sequence
<400>216
attcagagga tattcttcat aactctctag ataatgatga atgtagcacg cattcacata 60
aggtttttgc tgacattcag agtgaagaaa ttttacaaca taaccaaaat atgtctg 117
<210>217
<211>120
<212>DNA
<213> Artificial sequence
<400>217
attcagtcat tgaaaattca gccttagctt tttacacaag ttgtagtaga aaaacttctg 60
tgagtcagac ttcattactt gaagcaaaaa aatggcttag agaaggaata tttgatggtc 120
<210>218
<211>120
<212>DNA
<213> Artificial sequence
<400>218
attctcctca gatgactcca tttaaaaaat tcaatgaaat ttctcttttg gaaagtaatt 60
caatagctga cgaagaactt gcattgataa atacccaagc tcttttgtct ggttcaacag 120
<210>219
<211>121
<212>DNA
<213> Artificial sequence
<400>219
attctgatga ggtatataat gattcaggat atctctcaaa aaataaactt gattctggta 60
ttgagccagt attgaagaat gttgaagatc aaaaaaacac tagtttttcc aaagtaatat 120
c 121
<210>220
<211>120
<212>DNA
<213> Artificial sequence
<400>220
attgaactta cagatgggtg gtatgctgtt aaggcccagt tagatcctcc cctcttagct 60
gtcttaaaga atggcagact gacagttggt cagaagatta ttcttcatgg agcagaactg 120
<210>221
<211>115
<212>DNA
<213> Artificial sequence
<400>221
attgagcctc atttattttc tttttctccc cccctaccct gctagtctgg agttgatcaa 60
ggaacctgtc tccacaaagt gtgaccacat attttgcaag taagtttgaa tgtgt 115
<210>222
<211>120
<212>DNA
<213> Artificial sequence
<400>222
atttattttg aaacaaacat ttaaatgata atcacttctt ccattgcatc tttctcatct 60
ttctccaaac agttatactg agtatttggc gtccatcatc agatttatat tctctgttaa 120
<210>223
<211>119
<212>DNA
<213> Artificial sequence
<400>223
atttgtcaat cctagccttc caagagaaga aaaagaagag aaactagaaa cagttaaagt 60
gtctaataat gctgaagacc ccaaagatct catgttaagt ggagaaaggg ttttgcaaa 119
<210>224
<211>126
<212>DNA
<213> Artificial sequence
<400>224
atttttatct tacagtcaga aatgaagaag catctgaaac tgtatttcct catgatacta 60
ctgctgtaag taaatatgac attgattaga ctgttgaaat tgctaacaat tttggaatgc 120
cttgtt 126
<210>225
<211>114
<212>DNA
<213> Artificial sequence
<400>225
caaaaacaga accaaataaa tgtgtgagtc agtgtgcagc atttgaaaac cccaagggac 60
taattcatgg ttgttccaaa gataatagaa atgacacaga aggctttaag tatc 114
<210>226
<211>120
<212>DNA
<213> Artificial sequence
<400>226
caaaaacatc cactctgcct cgaatctctc tgaaagcagc agtaggaggc caagttccct 60
ctgcgtgttc tcataaacag gtatgtgttt gtctacaata ctgatggctt ttatgacaga 120
<210>227
<211>120
<212>DNA
<213> Artificial sequence
<400>227
caaaaagcaa aaaagtttca gatataaaag aagaggtctt ggctgcagca tgtcacccag 60
tacaacattc aaaagtggaa tacagtgata ctgactttca atcccagaaa agtcttttat 120
<210>228
<211>109
<212>DNA
<213> Artificial sequence
<400>228
caaaaggtga ttctattcag aatgagaaaa atcctaaccc aatagaatca ctcgaaaaag 60
aatctgcttt caaaacgaaa gctgaaccta taagcagcag tataagcaa 109
<210>229
<211>120
<212>DNA
<213> Artificial sequence
<400>229
caaaagtgtc catgatagac tagtacatct aaaagttggt taaccagaat atctttatgt 60
aggattcaga gtaaaatcaa agtgtttgtt ccaatacagc agatgaaata ttacctagat 120
<210>230
<211>117
<212>DNA
<213> Artificial sequence
<400>230
caaaccataa tttaacacct agccaaaagg cagaaattac agaactttct actatattag 60
aagaatcagg aagtcagttt gaatttactc agtttagaaa accaagctac atattgc 117
<210>231
<211>118
<212>DNA
<213> Artificial sequence
<400>231
caaactgtaa atgaagatat ttgcgttgag gaacttgtga ctagctcttc accctgcaaa 60
aataaaaatg cagccattaa attgtccata tctaatagta ataattttga ggtagggc 118
<210>232
<211>111
<212>DNA
<213> Artificial sequence
<400>232
caaagatctc atgttaagtg gagaaagggt tttgcaaact gaaagatctg tagagagtag 60
cagtatttca ttggtacctg gtactgatta tggcactcag gaaagtatct c 111
<210>233
<211>120
<212>DNA
<213> Artificial sequence
<400>233
caaatcacag ttttggaggt agcttcagaa cagcttcaaa taaggaaatc aagctctctg 60
aacataacat taagaagagc aaaatgttct tcaaagatat tgaagaacaa tatcctacta 120
<210>234
<211>120
<212>DNA
<213> Artificial sequence
<400>234
caaggaatat tataagaagt atatatggag gccatcgtat attctgttgt atacctagta 60
aacatggtaa aatgtaatta aacttaatta gaaaatgtgg ttgttatgtg gctcctgtaa 120
<210>235
<211>120
<212>DNA
<213> Artificial sequence
<400>235
caaggtattc tgtaaaggtt cttggtatac ctgttttcat aacaacatga gtagtctctt 60
cagtaattag attagttaaa gtgatgtggt gttttctggc aaacttgtac acgagcatct 120
<210>236
<211>120
<212>DNA
<213> Artificial sequence
<400>236
caagtaaaaa tgatactgtt tgtattcata aagatgaaac ggacttgcta tttactgatc 60
agcacaacat atgtcttaaa ttatctggcc agtttatgaa ggagggaaac actcagatta 120
<210>237
<211>120
<212>DNA
<213> Artificial sequence
<400>237
caagtggaaa atctgtccag gtatcagatg cttcattaca aaacgcaaga caagtgtttt 60
ctgaaataga agatagtacc aagcaagtct tttccaaagt attgtttaaa agtaacgaac 120
<210>238
<211>120
<212>DNA
<213> Artificial sequence
<400>238
caagtggaaa gcaagtttcc attttagaaa gttccttaca caaagttaag ggagtgttag 60
aggaatttga tttaatcaga actgagcata gtcttcacta ttcacctacg tctagacaaa 120
<210>239
<211>120
<212>DNA
<213> Artificial sequence
<400>239
caatagctga cgaagaactt gcattgataa atacccaagc tcttttgtct ggttcaacag 60
gagaaaaaca atttatatct gtcagtgaat ccactaggac tgctcccacc agttcagaag 120
<210>240
<211>120
<212>DNA
<213> Artificial sequence
<400>240
caatgcagag gttgaagatg gtatgttgcc aacacgagct gactctgggg ctctgtcttc 60
agaaggatca gattcagggt catcagagaa gaggctgatt ccagattcca ggtaaggggt 120
<210>241
<211>114
<212>DNA
<213> Artificial sequence
<400>241
cacaaaatac tgaaagaaag tgtcccagtt ggtactggaa atcaactagt gaccttccag 60
ggacaacccg aacgtgatga aaagatcaaa gaacctactc tattgggttt tcat 114
<210>242
<211>120
<212>DNA
<213> Artificial sequence
<400>242
cacaaactgt aaatgaagat atttgcgttg aggaacttgt gactagctct tcaccctgca 60
aaaataaaaa tgcagccatt aaattgtcca tatctaatag taataatttt gaggtagggc 120
<210>243
<211>120
<212>DNA
<213> Artificial sequence
<400>243
cacacacgct ttttacctga gtggttaaaa tgtcactctg agaggatagc cctgagcagt 60
cttcagagac gcttgtttca ctctcacacc cagatgctgc ttcaccttaa ataacaaaaa 120
<210>244
<211>111
<212>DNA
<213> Artificial sequence
<400>244
cacagttttg gaggtagctt cagaacagct tcaaataagg aaatcaagct ctctgaacat 60
aacattaaga agagcaaaat gttcttcaaa gatattgaag aacaatatcc t 111
<210>245
<211>104
<212>DNA
<213> Artificial sequence
<400>245
caccactgag aagcgtgcag ctgagaggca tccagaaaag tatcagggta gttctgtttc 60
aaacttgcat gtggagccat gtggcacaaa tactcatgcc agct 104
<210>246
<211>120
<212>DNA
<213> Artificial sequence
<400>246
caccatcttt cagtaatttg ccaaaatgac gaacacaaag ggaaagagga gaggcacctg 60
atatatgttc tctaggcctt ttagaaaaca tggagttgtt cctttggcca tgtatatgcg 120
<210>247
<211>120
<212>DNA
<213> Artificial sequence
<400>247
cacctgcatt taggatagcc agtggtaaaa tcgtttgtgt ttcacatgaa acaattaaaa 60
aagtgaaaga catatttaca gacagtttca gtaaagtaat taaggaaaac aacgagaata 120
<210>248
<211>124
<212>DNA
<213> Artificial sequence
<400>248
cactaaagac agaatgaatg tagaaaaggc tgaattctgt aataaaagca aacagcctgg 60
cttagcaagg agccaacata acagatgggc tggaagtaag gaaacatgta atgataggcg 120
gact 124
<210>249
<211>107
<212>DNA
<213> Artificial sequence
<400>249
cactgaatta ttgtactgtt tcaggaagga atgttcccaa tagtagacat aaaagtcttc 60
gcacagtgaa aactaaaatg gatcaagcag atgatgtttc ctgtcca 107
<210>250
<211>120
<212>DNA
<213> Artificial sequence
<400>250
cactggaacc tatttcatta atactggagc ccacttcatt agtactggaa cctacttcat 60
taatattgct tgagctggct tctttaaaaa cattttctct aatgttatta cggctaattg 120
<210>251
<211>120
<212>DNA
<213> Artificial sequence
<400>251
cacttttaca tattaaagcc tcatgaggat cactggccag taagtctatt ttctctgaag 60
aaccagaata ttcatctacc tcatttagaa cgtccaatac atcagctact ttggcatttg 120
<210>252
<211>120
<212>DNA
<213> Artificial sequence
<400>252
cagaaaggcc ttctggattc tggcttatag ggtattcact acttttctgt gaagttaata 60
ctgctttaaa tggaatgaga aaacaaatct actttactgc tttgttctga tagtgataat 120
<210>253
<211>120
<212>DNA
<213> Artificial sequence
<400>253
cagaaggaaa gagatacaga atttatcatc ttgcaacttc aaaatctaaa agtaaatctg 60
aaagagctaa catacagtta gcagcgacaa aaaaaactca gtatcaacaa ctaccggtac 120
<210>254
<211>113
<212>DNA
<213> Artificial sequence
<400>254
cagaattctg tagctttgaa gaatgcaggt ttaatatcca ctttgaaaaa gaaaacaaat 60
aagtttattt atgctataca tgatgaaaca tcttataaag gaaaaaaaat acc 113
<210>255
<211>120
<212>DNA
<213> Artificial sequence
<400>255
cagaggttca gatgtaaaag cagactataa acgctgcaac ttgctgtgtc tttttcttct 60
cattggcagg actggattta ctttcatgtc acacaaaatg attaaattcc ttgctttggg 120
<210>256
<211>114
<212>DNA
<213> Artificial sequence
<400>256
cagatgacta tcttaaagac cacttctgag gaatgcagag atgctgatct tcatgtcata 60
atgaatgccc catcgattgg tcaggtagac agcagcaagc aatttgaagg taca 114
<210>257
<211>101
<212>DNA
<213> Artificial sequence
<400>257
cagatgctcg tgtacaagtt tgccagaaaa caccacatca ctttaactaa tctaattact 60
gaagagacta ctcatgttgt tatgaaaaca ggtataccaa g 101
<210>258
<211>120
<212>DNA
<213> Artificial sequence
<400>258
cagattctaa actgccaagt catgccacac attctctttt tacatgtccc gaaaatgagg 60
aaatggtttt gtcaaattca agaattggaa aaagaagagg agagcccctt atcttagtgg 120
<210>259
<211>113
<212>DNA
<213> Artificial sequence
<400>259
cagcaattgg gcagatgtgt gaggcacctg tggtgacccg agagtgggtg ttggacagtg 60
tagcactcta ccagtgccag gagctggaca cctacctgat accccagatc ccc 113
<210>260
<211>120
<212>DNA
<213> Artificial sequence
<400>260
cagcattatt agacacttta actgtttcta gtttctcttc tttttcttct cttggaaggc 60
taggattgac aaattcttta agttcactgg tatttgaaca cttagtaaaa gaaccaggtg 120
<210>261
<211>120
<212>DNA
<213> Artificial sequence
<400>261
cagcattcag atctaccttt ttttctgtgc tgggagtccg cctatcatta catgtttcct 60
tacttccagc ccatctgtta tgttggctcc ttgctaagcc aggctgtttg cttttattac 120
<210>262
<211>120
<212>DNA
<213> Artificial sequence
<400>262
cagctgaaaa tatacaaaaa taacaaggta ctcaaaaact gaattgtcat taaaaaaata 60
catacttcat acaccttgga ggtggaaatc aaccaactgg ctatattaga gaaactaacc 120
<210>263
<211>114
<212>DNA
<213> Artificial sequence
<400>263
cagctgctgc tcatactact gatactgctg ggtataatgc aatggaagaa agtgtgagca 60
gggagaagcc agaattgaca gcttcaacag aaagggtcaa caaaagaatg tcca 114
<210>264
<211>120
<212>DNA
<213> Artificial sequence
<400>264
cagctttcgt tttgaaagca gattcttttt cgagtgattc tattgggtta ggatttttct 60
cattctgaat agaatcacct tttgttttat tctcatgacc actattagta atattcatca 120
<210>265
<211>120
<212>DNA
<213> Artificial sequence
<400>265
caggaagtca gtttgaattt actcagttta gaaaaccaag ctacatattg cagaagagta 60
catttgaagt gcctgaaaac cagatgacta tcttaaagac cacttctgag gaatgcagag 120
<210>266
<211>120
<212>DNA
<213> Artificial sequence
<400>266
caggtattga caaattttat ataactttat aaattacacc gagaaagtgt tttctaaaaa 60
atgcttgcta aaaacccagt acgtcacagt gttgcttaga accataaact gttccttatg 120
<210>267
<211>120
<212>DNA
<213> Artificial sequence
<400>267
caggtcatat gactgatcca aactttaaaa aagaaactga agcctctgaa agtggactgg 60
aaatacatac tgtttgctca cagaaggagg actccttatg tccaaattta attgataatg 120
<210>268
<211>120
<212>DNA
<213> Artificial sequence
<400>268
caggtctaaa tggagcccag atggagaaaa tacccctatt gcatatttct tcatgtgacc 60
aaaatatttc agaaaaagac ctattagaca cagagaacaa aagaaagaaa gattttctta 120
<210>269
<211>118
<212>DNA
<213> Artificial sequence
<400>269
catactgttt gctcacagaa ggaggactcc ttatgtccaa atttaattga taatggaagc 60
tggccagcca ccaccacaca gaattctgta gctttgaaga atgcaggttt aatatcca 118
<210>270
<211>109
<212>DNA
<213> Artificial sequence
<400>270
catatttctg aaagtctagg agctgaggtg gatcctgata tgtcttggtc aagttcttta 60
gctacaccac ccacccttag ttctactgtg ctcataggta ataatagca 109
<210>271
<211>120
<212>DNA
<213> Artificial sequence
<400>271
catcatctga aaccaattcc ttgtcactca gaccaactcc ctggctttca gactgatgcc 60
tcatttgttt ggaagaacca atcaagaaag gatcctgggtgtttgtattt gcagtcaagt 120
<210>272
<211>109
<212>DNA
<213> Artificial sequence
<400>272
catgaggctt taatatgtaa aagtgaaaga gttcactcca aatcagtaga gagtaatatt 60
gaagacaaaa tatttgggaa aacctatcgg aagaaggcaa gcctcccca 109
<210>273
<211>120
<212>DNA
<213> Artificial sequence
<400>273
cattattact gggttgatga tgttcagtat ttgttacatc cgtctcagaa aattcacaag 60
cagctgaaaa tatacaaaaa taacaaggta ctcaaaaact gaattgtcat taaaaaaata 120
<210>274
<211>120
<212>DNA
<213> Artificial sequence
<400>274
cattcactga aaattgtaaa gcctataatt gtctcaaatt ttttgtgtat ttacagtaac 60
atggatattc tcttagattt taactaatat gtaatataaa ataattgttt cctaggcaca 120
<210>275
<211>120
<212>DNA
<213> Artificial sequence
<400>275
cattctgaat agaatcacct tttgttttat tctcatgacc actattagta atattcatca 60
cttgaccatt ctgctccgtt tggttagttc cctgatttat catttcagga gtcttttgaa 120
<210>276
<211>105
<212>DNA
<213> Artificial sequence
<400>276
cattctgaca taagaaagaa caaaatggac attctaagtt atgaggaaac agacatagtt 60
aaacacaaaa tactgaaaga aagtgtccca gttggtactg gaaat 105
<210>277
<211>120
<212>DNA
<213> Artificial sequence
<400>277
catttagctc acttctataa atagactggg gcaaacacaa aaacctggtt ccaataccta 60
agtttgaatc catgctttgc tcttcttgat tattttcttc caagcccgtt cctctttctt 120
<210>278
<211>120
<212>DNA
<213> Artificial sequence
<400>278
catttctatt atctttggaa caaccatgaa ttagtccctt ggggttttca aatgctgcac 60
actgactcac acatttattt ggttctgttt ttgccttccc tagagtgcta acttccagta 120
<210>279
<211>120
<212>DNA
<213> Artificial sequence
<400>279
catttgaagt gcctgaaaac cagatgacta tcttaaagac cacttctgag gaatgcagag 60
atgctgatct tcatgtcata atgaatgccc catcgattgg tcaggtagac agcagcaagc 120
<210>280
<211>120
<212>DNA
<213> Artificial sequence
<400>280
catttgttaa cttcagctct gggaaagtat cgctgtcatg tcttttactt gtctgttcat 60
ttggcttgtt actcttcttg gctccagttg caggttcttt accttccatg agttgtaggt 120
<210>281
<211>120
<212>DNA
<213> Artificial sequence
<400>281
cattttgtac ttcttcaacg cgaagagcag ataaatccat ttctttctgt tccaatgaac 60
tttaacacat tagaaaaaca tatatatata tctttttaaa aggtttataa aatgacaact 120
<210>282
<211>124
<212>DNA
<213> Artificial sequence
<400>282
catttttctc taactgcaaa cataatgttt tcccttgtat tttacagatg caaacagcta 60
taattttgca aaaaaggaaa ataactctcc tgaacatcta aaagatgaag tttctatcat 120
ccaa 124
<210>283
<211>120
<212>DNA
<213> Artificial sequence
<400>283
ccactcctgg ttctttattt ttactggtag aactatctgc agacacctca aacttgtcag 60
cagaaaggcc ttctggattc tggcttatag ggtattcact acttttctgt gaagttaata 120
<210>284
<211>120
<212>DNA
<213> Artificial sequence
<400>284
ccacttattt tcttagaata ttgacatact ttgcaatgaa gcagaaaaca agcttatgca 60
tatactgcat gcaaatgatc ccaagtggtc caccccaact aaagactgta cttcagggcc 120
<210>285
<211>120
<212>DNA
<213> Artificial sequence
<400>285
ccactttgaa aaagaaaaca aataagttta tttatgctat acatgatgaa acatcttata 60
aaggaaaaaa aataccgaaa gaccaaaaat cagaactaat taactgttca gcccagtttg 120
<210>286
<211>114
<212>DNA
<213> Artificial sequence
<400>286
ccagttgata atgccaaatg tagtatcaaa ggaggctcta ggttttgtct atcatctcag 60
ttcagaggca acgaaactgg actcattact ccaaataaac atggactttt acaa 114
<210>287
<211>114
<212>DNA
<213> Artificial sequence
<400>287
ccattttatc aagtttctgc tacaagaaat gaaaaaatga gacacttgat tactacaggc 60
agaccaacca aagtctttgt tccacctttt aaaactaaat cacattttca caga 114
<210>288
<211>120
<212>DNA
<213> Artificial sequence
<400>288
cccaaaaagg cttttcatat aatgtggtaa attcatctgc tttctctgga tttagtacag 60
caagtggaaa gcaagtttcc attttagaaa gttccttaca caaagttaag ggagtgttag 120
<210>289
<211>118
<212>DNA
<213> Artificial sequence
<400>289
cccatcaagt catttgttaa aactaaatgt aagaaaaatc tgctagagga aaactttgag 60
gaacattcaa tgtcacctga aagagaaatg ggaaatgaga acattccaag tacagtga 118
<210>290
<211>120
<212>DNA
<213> Artificial sequence
<400>290
cccttaccca attcaatgta gacagacgtc ttttgaggtt gtatccgctg ctttgtcctc 60
agagttctca cagttccaag gttagagagt tggacactga gactggtttc ctgctaaaca 120
<210>291
<211>123
<212>DNA
<213> Artificial sequence
<400>291
cccttctaaa tgcccatcat tagatgatag gtggtacatg cacagttgct ctgggagtct 60
tcagaataga aactacccat ctcaagagga gctcattaag gttgttgatg tggaggagca 120
aca 123
<210>292
<211>116
<212>DNA
<213> Artificial sequence
<400>292
ccctttgaga gtggaagtga caaaatctcc aaggaagttg taccgtcttt ggcctgtgaa 60
tggtctcaac taaccctttc aggtctaaat ggagcccaga tggagaaaat acccct 116
<210>293
<211>120
<212>DNA
<213> Artificial sequence
<400>293
cctcaaagtt ttcctctagc agatttttct tacatttagt tttaacaaat gacttgatgg 60
gaaaaagtgg tggtatacga tatgggtttt gtaaaagtcc atgtttattt ggagtaatga 120
<210>294
<211>117
<212>DNA
<213> Artificial sequence
<400>294
cctgaaataa aaaagcaaga atatgaagaa gtagttcaga ctgttaatac agatttctct 60
ccatatctga tttcagataa cttagaacag cctatgggaa gtagtcatgc atctcag 117
<210>295
<211>120
<212>DNA
<213> Artificial sequence
<400>295
cctgagatgc atgactactt cccataggct gttctaagtt atctgaaatc agatatggag 60
agaaatctgt attaacagtc tgaactactt cttcatattc ttgctttttt atttcaggat 120
<210>296
<211>116
<212>DNA
<213> Artificial sequence
<400>296
cctgatgcct gtacacctct tgaagcccca gaatctctta tgttaaaggt aaattaattt 60
gcactcttgg taaaaatcag tcattgattc agttaaattc tagaagtttt acattt 116
<210>297
<211>120
<212>DNA
<213> Artificial sequence
<400>297
cctgggttat gaaggacaaa aacaaaagct aataatggag ccacataaca cattcaaact 60
tacttgcaaa atatgtggtc acactttgtg gagacaggtt ccttgatcaa ctccagacta 120
<210>298
<211>120
<212>DNA
<213> Artificial sequence
<400>298
cctgttgttc tacaatgtac acatgtaaca ccacaaagag ataagtcagg tatgattaaa 60
aacaatgctt tttattctta gaatactaga aatgttaata aaaataaaac ttaacaattt 120
<210>299
<211>120
<212>DNA
<213> Artificial sequence
<400>299
ccttaaattc tgaattacat tctgacataa gaaagaacaa aatggacatt ctaagttatg 60
aggaaacaga catagttaaa cacaaaatac tgaaagaaag tgtcccagtt ggtactggaa 120
<210>300
<211>110
<212>DNA
<213> Artificial sequence
<400>300
ccttattcac taaaattcag gaggaatttg aagaacatga aggtaaaatt agttatatgg 60
tacacattgt tatttctaat atgagaacaa agtcttagag actttgaatt 110
<210>301
<211>118
<212>DNA
<213> Artificial sequence
<400>301
ccttgaatat agataaaata ccagaaaaaa ataatgatta catgaacaaa tgggcaggac 60
tcttaggtcc aatttcaaat cacagttttg gaggtagctt cagaacagct tcaaataa 118
<210>302
<211>120
<212>DNA
<213> Artificial sequence
<400>302
cgcttctgag ttttacctca gtcacataat aaggaatgca tccctgtgta agtgcatttt 60
ggtcttctgt tttgcagact tatttaccaa gcattggagg aatatcgtag gtaaaaatgc 120
<210>303
<211>113
<212>DNA
<213> Artificial sequence
<400>303
cgtttgtgtt tcacatgaaa caattaaaaa agtgaaagac atatttacag acagtttcag 60
taaagtaatt aaggaaaaca acgagaataa atcaaaaatt tgccaaacga aaa 113
<210>304
<211>120
<212>DNA
<213> Artificial sequence
<400>304
ctaaatattt atatgtgtac tagtcaataa acttatatat tttctcccca ttgcagcaca 60
actaaggaac gtcaagagat acagaatcca aattttaccg cacctggtca agaatttctg 120
<210>305
<211>120
<212>DNA
<213> Artificial sequence
<400>305
ctacagatct ttcagtttgc aaaacccttt ctccacttaa catgagatct ttggggtctt 60
cagcattatt agacacttta actgtttcta gtttctcttc tttttcttct cttggaaggc 120
<210>306
<211>120
<212>DNA
<213> Artificial sequence
<400>306
ctactggcac ttttgttgaa gaaattactg aaaattacaa gagaaatact gaaaatgaag 60
ataacaaata tactgctgcc agtagaaatt ctcataactt agaatttgat ggcagtgatt 120
<210>307
<211>111
<212>DNA
<213> Artificial sequence
<400>307
ctagagatac tgaagatgtt ccttggataa cactaaatag cagcattcag aaagttaatg 60
agtggttttc cagaagtgat gaactgttag gttctgatga ctcacatgat g 111
<210>308
<211>120
<212>DNA
<213> Artificial sequence
<400>308
ctagtgattt taaactataa tttttgcaga atgtgaaaag ctatttttcc aatcatgatg 60
aaagtctgaa gaaaaatgat agatttatcg cttctgtgac agacagtgaa aacacaaatc 120
<210>309
<211>120
<212>DNA
<213> Artificial sequence
<400>309
ctattgagac tgtggtgcca cctaagctct taagtgataa tttatgtaga caaactgaaa 60
atctcaaaac atcaaaaagt atctttttga aagttaaagt acatgaaaat gtagaaaaag 120
<210>310
<211>120
<212>DNA
<213> Artificial sequence
<400>310
ctattggatc caaagagagg ccaacatttt ttgaaatttt taagacacgc tgcaacaaag 60
caggtattga caaattttat ataactttat aaattacacc gagaaagtgt tttctaaaaa 120
<210>311
<211>120
<212>DNA
<213> Artificial sequence
<400>311
ctcagatcca gttggaaatt aggaaggcca tggaatctgc tgaacaaaag gaacaaggtt 60
tatcaaggga tgtcacaacc gtgtggaagt tgcgtattgt aagctattca aaaaaagaaa 120
<210>312
<211>111
<212>DNA
<213> Artificial sequence
<400>312
ctcatttgta tctgaagtgg aaccaaatga tactgatcca ttagattcaa atgtagcaaa 60
tcagaagccc tttgagagtg gaagtgacaa aatctccaag gaagttgtac c 111
<210>313
<211>120
<212>DNA
<213> Artificial sequence
<400>313
ctcctataat tagattttca gttacatggc ttaagttggg gaggcttgcc ttcttccgat 60
aggttttccc aaatattttg tcttcaatat tactctctac tgatttggag tgaactcttt 120
<210>314
<211>120
<212>DNA
<213> Artificial sequence
<400>314
ctcctttctg gacgcttttg ctaaaaacag cagaactttc cttaatgtca ttttcagcaa 60
aactagtatc ttcctttatt tcaccatcat ctaacaggtc atcaggtgtc tcagaacaaa 120
<210>315
<211>111
<212>DNA
<213> Artificial sequence
<400>315
ctctgccctt atcatcgctt ttcagtgatg gaggaaatgt tggttgtgtt gatgtaatta 60
ttcaaagagc ataccctata caggtatgat gtattcttga aacttaccat a 111
<210>316
<211>120
<212>DNA
<213> Artificial sequence
<400>316
ctcttcggta accctgagcc aaatgtgtat gggtgaaagg gctaggactc ctgctaagct 60
ctcctttctg gacgcttttg ctaaaaacag cagaactttc cttaatgtca ttttcagcaa 120
<210>317
<211>120
<212>DNA
<213> Artificial sequence
<400>317
ctgaaataga agatagtacc aagcaagtct tttccaaagt attgtttaaa agtaacgaac 60
attcagacca gctcacaaga gaagaaaata ctgctatacg tactccagaa catttaatat 120
<210>318
<211>113
<212>DNA
<213> Artificial sequence
<400>318
ctgacagatt ctaaactgcc aagtcatgcc acacattctc tttttacatg tcccgaaaat 60
gaggaaatgg ttttgtcaaa ttcaagaatt ggaaaaagaa gaggagagcc cct 113
<210>319
<211>120
<212>DNA
<213> Artificial sequence
<400>319
ctgaggtgga cctaatagga tttgtcgttt ctgttgtgaa aaaaacaggt aatgcacaat 60
atagttaatt ttttttattg attcttttaa aaaacattgt cttttaaaat ctcttatgat 120
<210>320
<211>120
<212>DNA
<213> Artificial sequence
<400>320
ctgatgttcc tgtgaaaaca aatatagaag tttgttctac ttactccaaa gattcagaaa 60
actactttga aacagaagca gtagaaattg ctaaagcttt tatggaagat gatgaactga 120
<210>321
<211>111
<212>DNA
<213> Artificial sequence
<400>321
ctgcaggaag gacagtgtga aaatgatcca aaaagcaaaa aagtttcaga tataaaagaa 60
gaggtcttgg ctgcagcatg tcacccagta caacattcaa aagtggaata c 111
<210>322
<211>120
<212>DNA
<213> Artificial sequence
<400>322
ctgccaaatc tgctttcttg ataaaatcct caggatgaag gcctgatgta ggtctccttt 60
tacgctttaa tttatttgtg aggggacgct cttgtattat ctgtggctca gtaacaaatg 120
<210>323
<211>120
<212>DNA
<213> Artificial sequence
<400>323
ctgcgtgttc tcataaacag gtatgtgttt gtctacaata ctgatggctt ttatgacaga 60
gtgtaatttt atttcattaa ctagtatcta caaatggctt tgtttaaaga atgaacacat 120
<210>324
<211>120
<212>DNA
<213> Artificial sequence
<400>324
ctgctcatgg cacaaaactg aatgtttcta ctgaagctct gcaaaaagct gtgaaactgt 60
ttagtgatat tgagaatatt agtgaggaaa cttctgcaga ggtacatcca ataagtttat 120
<210>325
<211>120
<212>DNA
<213> Artificial sequence
<400>325
ctgctttaaa tggaatgaga aaacaaatct actttactgc tttgttctga tagtgataat 60
tcaggttaga atactgattt ttttcaaaag catcaatcta tgatacacaa attggttttt 120
<210>326
<211>123
<212>DNA
<213> Artificial sequence
<400>326
ctgtttcatt tatgctttgg ctgcccagca agtatgattt gtcctttcac aattggtggc 60
gatggttttc tccttccatt tatctttcta ggtcatcccc ttctaaatgc ccatcattag 120
atg 123
<210>327
<211>120
<212>DNA
<213> Artificial sequence
<400>327
cttaatatta actaaatagg aaaataccag cttcatagac aaaggttctc tttgactcac 60
ctgcaataag ttgccttatt aacggtatct tcagaagaat cagatcctaa aaaatttccc 120
<210>328
<211>120
<212>DNA
<213> Artificial sequence
<400>328
cttacaactc cctatacatt ctcattccca gtatagagga gactttttgt ttttaaacac 60
ttccaaagaa tgcaaattta taatccagag tatatacatt ctcactgaat tattgtactg 120
<210>329
<211>119
<212>DNA
<213> Artificial sequence
<400>329
cttactccaa agattcagaa aactactttg aaacagaagc agtagaaatt gctaaagctt 60
ttatggaaga tgatgaactg acagattcta aactgccaag tcatgccaca cattctctt 119
<210>330
<211>120
<212>DNA
<213> Artificial sequence
<400>330
cttatgatct ttaactgttc tgggtcacaa atttgtctgt cactggttaa aactaaggtg 60
ggattttttt tttaaataga tttaggacca ataagtctta attggtttga agaactttct 120
<210>331
<211>120
<212>DNA
<213> Artificial sequence
<400>331
cttatgatgg aagggtagct gttagaaggc tggctcccat gctgttctaa cacagcttct 60
agttcagcca tttcctgctg gagctttatc aggttatgtt gcatggtatc cctctgcttc 120
<210>332
<211>120
<212>DNA
<213> Artificial sequence
<400>332
cttcaagtaa atgtcatgat tctgttgttt caatgtttaa gatagaaaat cataatgata 60
aaactgtaag tgaaaaaaat aataaatgcc aactgatatt acaaaataat attgaaatga 120
<210>333
<211>120
<212>DNA
<213> Artificial sequence
<400>333
cttcagagaa ttctttgcca cgtatttcta gcctaccaaa atcagagaag ccattaaatg 60
aggaaacagt ggtaaataag agagatgaag agcagcatct tgaatctcat acagactgca 120
<210>334
<211>120
<212>DNA
<213> Artificial sequence
<400>334
cttcagagac gcttgtttca ctctcacacc cagatgctgc ttcaccttaa ataacaaaaa 60
cagaggttca gatgtaaaag cagactataa acgctgcaac ttgctgtgtc tttttcttct 120
<210>335
<211>120
<212>DNA
<213> Artificial sequence
<400>335
cttccaattc actgcactgt gaagaaaaca agctagcaga acattttgtt tcctcactaa 60
ggtgatgttc ctgagatgcc tttgccaata ttacctggtt actgcagtca tttaagctat 120
<210>336
<211>120
<212>DNA
<213> Artificial sequence
<400>336
cttctcctaa ttgtgagata tattatcaaa gtcctttatc actttgtatg gccaaaagga 60
agtctgtttc cacacctgtc tcagcccaga tgacttcaaa gtcttgtaaa ggggagaaag 120
<210>337
<211>120
<212>DNA
<213> Artificial sequence
<400>337
cttctgtgaa aagaagctgt tcacagaatg attctgaaga accaactttg tccttaacta 60
gctcttttgg gacaattctg aggaaatgtt ctagaaatga aacatgttct aataatacag 120
<210>338
<211>119
<212>DNA
<213> Artificial sequence
<400>338
cttctgtgag tcagacttca ttacttgaag caaaaaaatg gcttagagaa ggaatatttg 60
atggtcaacc agaaagaata aatactgcag attatgtagg aaattatttg tatgaaaat 119
<210>339
<211>120
<212>DNA
<213> Artificial sequence
<400>339
cttgaccatt ctgctccgtt tggttagttc cctgatttat catttcagga gtcttttgaa 60
ctgccaaatc tgctttcttg ataaaatcct caggatgaag gcctgatgta ggtctccttt 120
<210>340
<211>120
<212>DNA
<213> Artificial sequence
<400>340
cttgcccctt tcgtctattt gtcagacgaa tgttacaatt tactggcaat aaagttttgg 60
atagacctta atgaggacat tattaagcct catatgttaa ttgctgcaag caacctccag 120
<210>341
<211>120
<212>DNA
<213> Artificial sequence
<400>341
cttgccttgg caagtaagat gtttccgtca aatcgtgtgg cccagactct tccagctgtt 60
gctcctccac atcaacaacc ttaatgagct cctcttgaga tgggtagttt ctattctgaa 120
<210>342
<211>120
<212>DNA
<213> Artificial sequence
<400>342
cttgctcgct ttggaccttg gtggtttctt ccattgacca catctcctct gacttcaaaa 60
tcatgctgaa agaaaccaaa cacaacccat caggataaga gaaagagaag cttccttcaa 120
<210>343
<211>116
<212>DNA
<213> Artificial sequence
<400>343
cttggcatta gataatcaaa agaaactgag caagcctcag tcaattaata ctgtatctgc 60
acatttacag agtagtgtag ttgtttctga ttgtaaaaat agtcatataa cccctc 116
<210>344
<211>110
<212>DNA
<213> Artificial sequence
<400>344
cttgttattt ggtaaagtaa acaatatacc ttctcagtct actaggcata gcaccgttgc 60
taccgagtgt ctgtctaaga acacagagga gaatttatta tcattgaaga 110
<210>345
<211>120
<212>DNA
<213> Artificial sequence
<400>345
ctttacctcc acctgttagt cccatttgta catttgtttc tccggctgca cagaaggcat 60
ttcagccacc aaggagttgt ggcaccaaat acgaaacacc cataaagaaa aaagaactga 120
<210>346
<211>120
<212>DNA
<213> Artificial sequence
<400>346
cttttgaatt gtggatattt aattcgagtt ccatattgct tatactgctg cttataggtt 60
cagctttcgt tttgaaagca gattcttttt cgagtgattc tattgggtta ggatttttct 120
<210>347
<211>120
<212>DNA
<213> Artificial sequence
<400>347
gaaaaagtgg tggtatacga tatgggtttt gtaaaagtcc atgtttattt ggagtaatga 60
gtccagtttc gttgcctctg aactgagatg atagacaaaa cctagagcct cctttgatac 120
<210>348
<211>120
<212>DNA
<213> Artificial sequence
<400>348
gaaaagaaca ggcttcacct aaaaacgtaa aaatggaaat tggtaaaact gaaacttttt 60
ctgatgttcc tgtgaaaaca aatatagaag tttgttctac ttactccaaa gattcagaaa 120
<210>349
<211>116
<212>DNA
<213> Artificial sequence
<400>349
gaaagttcct tacacaaagt taagggagtg ttagaggaat ttgatttaat cagaactgag 60
catagtcttc actattcacc tacgtctaga caaaatgtat caaaaatact tcctcg 116
<210>350
<211>120
<212>DNA
<213> Artificial sequence
<400>350
gaagaagaga ggaagagaga gggacagggg aatggagaga aggaaaatct agttataaaa 60
gaatattggc ttttattcaa aaaacagact ttcaaaaagg aagagctttt ctttttcttc 120
<210>351
<211>120
<212>DNA
<213> Artificial sequence
<400>351
gaagaatgtt gaagatcaaa aaaacactag tttttccaaa gtaatatcca atgtaaaaga 60
tgcaaatgca tacccacaaa ctgtaaatga agatatttgc gttgaggaac ttgtgactag 120
<210>352
<211>113
<212>DNA
<213> Artificial sequence
<400>352
gaagaggggc caagaaatta gagtcctcag aagagaactt atctagtgag gatgaagagc 60
ttccctgctt ccaacacttg ttatttggta aagtaaacaa tataccttct cag 113
<210>353
<211>120
<212>DNA
<213> Artificial sequence
<400>353
gaagcaaata catttttaac tatatgactg aatgaatatc tctggttagt ttgtaacatc 60
aagtacttac ctcattcagc atttttcttt ctttaataga ctgggtcacc cctaaagaga 120
<210>354
<211>120
<212>DNA
<213> Artificial sequence
<400>354
gaagctggcc agccaccacc acacagaatt ctgtagcttt gaagaatgca ggtttaatat 60
ccactttgaa aaagaaaaca aataagttta tttatgctat acatgatgaa acatcttata 120
<210>355
<211>115
<212>DNA
<213> Artificial sequence
<400>355
gaagttgcga aagctcaaga agcatgtcat ggtaatactt caaataaaga acagttaact 60
gctactaaaa cggagcaaaa tataaaagat tttgagactt ctgatacatt ttttc 115
<210>356
<211>119
<212>DNA
<213> Artificial sequence
<400>356
gaatcagatc ctaaaaaatt tccccccaaa aaataaatca ataaaagttt tcttaattaa 60
aagggttaaa aaaatgtact tgttgaaaaa cagatattca actagaaata tttactgag 119
<210>357
<211>122
<212>DNA
<213> Artificial sequence
<400>357
gaatctgctt tcaaaacgaa agctgaacct ataagcagca gtataagcaa tatggaactc 60
gaattaaata tccacaattc aaaagcacct aaaaagaata ggctgaggag gaagtcttct 120
ac 122
<210>358
<211>116
<212>DNA
<213> Artificial sequence
<400>358
gaattaacca aaaatattcc catggaaaag aatcaagatg tatgtgcttt aaatgaaaat 60
tataaaaacg ttgagctgtt gccacctgaa aaatacatga gagtagcatc accttc 116
<210>359
<211>108
<212>DNA
<213> Artificial sequence
<400>359
gaatttactc agtttagaaa accaagctac atattgcaga agagtacatt tgaagtgcct 60
gaaaaccaga tgactatctt aaagaccact tctgaggaat gcagagat 108
<210>360
<211>109
<212>DNA
<213> Artificial sequence
<400>360
gacaattctg aggaaatgtt ctagaaatga aacatgttct aataatacag taatctctca 60
ggatcttgat tataaagaag caaaatgtaa taaggaaaaa ctacagtta 109
<210>361
<211>111
<212>DNA
<213> Artificial sequence
<400>361
gacagcttca acagaaaggg tcaacaaaag aatgtccatg gtggtgtctg gcctgacccc 60
agaagaattt gtgagtgtat ccatatgtat ctccctaatg actaagactt a 111
<210>362
<211>120
<212>DNA
<213> Artificial sequence
<400>362
gactcccaga gcaactgtgc atgtaccacc tatcatctaa tgatgggcat ttagaagggg 60
atgacctaga aagataaatg gaaggagaaa accatcgcca ccaattgtga aaggacaaat 120
<210>363
<211>120
<212>DNA
<213> Artificial sequence
<400>363
gagaaaaaca atttatatct gtcagtgaat ccactaggac tgctcccacc agttcagaag 60
attatctcag actgaaacga cgttgtacta catctctgat caaagaacag gagagttccc 120
<210>364
<211>120
<212>DNA
<213> Artificial sequence
<400>364
gagaagactt ctgaggctac agtaggggca tccataggga ctgacaggtg ccagtcttgc 60
tcacaggaga gaatattgtg tcctccctct ctgacagggc acccaatact tactgtgcca 120
<210>365
<211>114
<212>DNA
<213> Artificial sequence
<400>365
gagaatatta gtgaggaaac ttctgcagag gtacatccaa taagtttatc ttcaagtaaa 60
tgtcatgatt ctgttgtttc aatgtttaag atagaaaatc ataatgataa aact 114
<210>366
<211>119
<212>DNA
<213> Artificial sequence
<400>366
gagataaaga aaaaaaagta caaccaaatg ccagtcaggc acagcagaaa cctacaactc 60
atggaaggta aagaacctgc aactggagcc aagaagagta acaagccaaa tgaacagac 119
<210>367
<211>116
<212>DNA
<213> Artificial sequence
<400>367
gagcaaaata taaaagattt tgagacttct gatacatttt ttcagactgc aagtgggaaa 60
aatattagtg tcgccaaaga gtcatttaat aaaattgtaa atttctttga tcagaa 116
<210>368
<211>120
<212>DNA
<213> Artificial sequence
<400>368
gagccacagg accccaagaa tgagcttaca aagtggcctt tccaggccct gggagctcct 60
ctcactcttc agtccttcta ctgtcctggc tactaaatat tttatgtaca tcagcctgaa 120
<210>369
<211>112
<212>DNA
<213> Artificial sequence
<400>369
gagctgaagt taacaaatgc acctggttct tttactaagt gttcaaatac cagtgaactt 60
aaagaatttg tcaatcctag ccttccaaga gaagaaaaag aagagaaact ag 112
<210>370
<211>116
<212>DNA
<213> Artificial sequence
<400>370
gagctgttgc cacctgaaaa atacatgaga gtagcatcac cttcaagaaa ggtacaattc 60
aaccaaaaca caaatctaag agtaatccaa aaaaatcaag aagaaactac ttcaat 116
<210>371
<211>110
<212>DNA
<213> Artificial sequence
<400>371
gaggagctca ttaaggttgt tgatgtggag gagcaacagc tggaagagtc tgggccacac 60
gatttgacgg aaacatctta cttgccaagg caagatctag gtaatatttc 110
<210>372
<211>120
<212>DNA
<213> Artificial sequence
<400>372
gagggaaggc tcagatacaa acacagctat taaaaagtca ttcctccttt tggccagaac 60
caccatcttt cagtaatttg ccaaaatgac gaacacaaag ggaaagagga gaggcacctg 120
<210>373
<211>120
<212>DNA
<213> Artificial sequence
<400>373
gaggtaaggt tacttttcag catcaccaca cattttggta tttttctatt ttgacagtcc 60
agtatcaagg aaatagcttt tatacaaatt ggatagttga ggtagtatgt gaggtaaagt 120
<210>374
<211>120
<212>DNA
<213> Artificial sequence
<400>374
gagtagcatc accttcaaga aaggtacaat tcaaccaaaa cacaaatcta agagtaatcc 60
aaaaaaatca agaagaaact acttcaattt caaaaataac tgtcaatcca gactctgaag 120
<210>375
<211>128
<212>DNA
<213> Artificial sequence
<400>375
gataggcgga ctcccagcac agaaaaaaag gtagatctga atgctgatcc cctgtgtgag 60
agaaaagaat ggaataagca gaaactgcca tgctcagaga atcctagaga tactgaagat 120
gttccttg 128
<210>376
<211>120
<212>DNA
<213> Artificial sequence
<400>376
gatatctctc aaaaaataaa cttgattctg gtattgagcc agtattgaag aatgttgaag 60
atcaaaaaaa cactagtttt tccaaagtaa tatccaatgt aaaagatgca aatgcatacc 120
<210>377
<211>120
<212>DNA
<213> Artificial sequence
<400>377
gatattcaac acttacactc caaacctgtg tcaagctgaa aagcacaaat gattttcaat 60
agctcttcaa caagttgact aaatctcgta ctttcttgta ggctcctgaa attaaattgt 120
<210>378
<211>107
<212>DNA
<213> Artificial sequence
<400>378
gatgaactgt taggttctga tgactcacat gatggggagt ctgaatcaaa tgccaaagta 60
gctgatgtat tggacgttct aaatgaggta gatgaatatt ctggttc 107
<210>379
<211>120
<212>DNA
<213> Artificial sequence
<400>379
gatgacacag ctgcaaaaac acttgttctc tgtgtttctg acataatttc attgagcgca 60
aatatatctg aaacttctag caataaaact agtagtgcag atacccaaaa agtggccatt 120
<210>380
<211>124
<212>DNA
<213> Artificial sequence
<400>380
gatgatgaag aaagaggaac gggcttggaa gaaaataatc aagaagagca aagcatggat 60
tcaaacttag gtattggaac caggtttttg tgtttgcccc agtctattta tagaagtgag 120
ctaa 124
<210>381
<211>120
<212>DNA
<213> Artificial sequence
<400>381
gatggacatg gctctgatga tagtaaaaat aagattaatg acaatgagat tcatcagttt 60
aacaaaaaca actccaatca agcagtagct gtaactttca caaagtgtga agaagaacct 120
<210>382
<211>116
<212>DNA
<213> Artificial sequence
<400>382
gatgtattgg acgttctaaa tgaggtagat gaatattctg gttcttcaga gaaaatagac 60
ttactggcca gtgatcctca tgaggcttta atatgtaaaa gtgaaagagt tcactc 116
<210>383
<211>112
<212>DNA
<213> Artificial sequence
<400>383
gattggtcag gtagacagca gcaagcaatt tgaaggtaca gttgaaatta aacggaagtt 60
tgctggcctg ttgaaaaatg actgtaacaa aagtgcttct ggttatttaa ca 112
<210>384
<211>120
<212>DNA
<213> Artificial sequence
<400>384
gattgttttc tagatttctt cctctaggtt attaattgac aatacctaca taaaactctt 60
tccagaatgt tgttaagtct tagtcattag ggagatacat atggatacac tcacaaattc 120
<210>385
<211>113
<212>DNA
<213> Artificial sequence
<400>385
gatttctaga ggcaaagaat catacaaaat gtcagacaag ctcaaaggta acaattatga 60
atctgatgtt gaattaacca aaaatattcc catggaaaag aatcaagatg tat 113
<210>386
<211>121
<212>DNA
<213> Artificial sequence
<400>386
gattttctgc ttgaagtctc ccttggaaat ctgccatgag cacaaaatta tggtaatttt 60
tcacctgaga agattttaaa accatttaaa cgccaccaat tgagcaagat gctgattcat 120
t 121
<210>387
<211>109
<212>DNA
<213> Artificial sequence
<400>387
gcaaaggcat ctcaggaaca tcaccttagt gaggaaacaa aatgttctgc tagcttgttt 60
tcttcacagt gcagtgaatt ggaagacttg actgcaaata caaacaccc 109
<210>388
<211>117
<212>DNA
<213> Artificial sequence
<400>388
gcaaatactt gtgggatttt tagcacagca agtggaaaat ctgtccaggt atcagatgct 60
tcattacaaa acgcaagaca agtgttttct gaaatagaag atagtaccaa gcaagtc 117
<210>389
<211>113
<212>DNA
<213> Artificial sequence
<400>389
gcaactggag ccaagaagag taacaagcca aatgaacaga caagtaaaag acatgacagc 60
gatactttcc cagagctgaa gttaacaaat gcacctggtt cttttactaa gtg 113
<210>390
<211>120
<212>DNA
<213> Artificial sequence
<400>390
gcaagatggt gcagagcttt atgaagcagt gaagaatgca gcagacccag cttaccttga 60
ggtgagagag taagaggaca tataatgagg cttgatgatt attcaaggtg agaagctgtt 120
<210>391
<211>120
<212>DNA
<213> Artificial sequence
<400>391
gcaatgaaag agaggaagaa aaggaagcag caaaatatgt ggaggcccaa caaaagagac 60
tagaagcctt attcactaaa attcaggagg aatttgaaga acatgaaggt aaaattagtt 120
<210>392
<211>120
<212>DNA
<213> Artificial sequence
<400>392
gcagaatcca aactgatttc atccctggtt ccttgagggg tgatttgtaa caattcttga 60
tctcccacac tatagggaaa agacagagtc ctaataagaa acactagtta catgtatgca 120
<210>393
<211>120
<212>DNA
<213> Artificial sequence
<400>393
gcagggtagg gggggagaaa aagaaaataa atgaggctca ataatttatt taaaaataaa 60
gctattctta gtgaataagt tcaactttga gctgttatga ctgagtcaac ataaggcctc 120
<210>394
<211>110
<212>DNA
<213> Artificial sequence
<400>394
gcatttgtta ctgagccaca gataatacaa gagcgtcccc tcacaaataa attaaagcgt 60
aaaaggagac ctacatcagg ccttcatcct gaggatttta tcaagaaagc 110
<210>395
<211>120
<212>DNA
<213> Artificial sequence
<400>395
gccactttgt aagctcattc ttggggtcct gtggctctgt acctgtggct ggctgcagtc 60
agtagtggct gtgggggatc tggggtatca ggtaggtgtc cagctcctgg cactggtaga 120
<210>396
<211>128
<212>DNA
<213> Artificial sequence
<400>396
gcctggccag gggttgtgct ttttaaattt caattttatt tttgctaagt atttattctt 60
tgatagattt aattacaagt cttcagaatg ccagagatat acaggatatg cgaattaaga 120
agaaacaa 128
<210>397
<211>120
<212>DNA
<213> Artificial sequence
<400>397
gctcataaaa ttcacttccc aaagctgcct accacaaata caaattatga ccaagatttt 60
tggcaaaact ataagataag gaatccagca attattatta aatacttaaa aaacctgaga 120
<210>398
<211>120
<212>DNA
<213> Artificial sequence
<400>398
gctcctccac atcaacaacc ttaatgagct cctcttgaga tgggtagttt ctattctgaa 60
gactcccaga gcaactgtgc atgtaccacc tatcatctaa tgatgggcat ttagaagggg 120
<210>399
<211>120
<212>DNA
<213> Artificial sequence
<400>399
gctcttttgg gacaattctg aggaaatgtt ctagaaatga aacatgttct aataatacag 60
taatctctca ggatcttgat tataaagaag caaaatgtaa taaggaaaaa ctacagttat 120
<210>400
<211>117
<212>DNA
<213> Artificial sequence
<400>400
gctgcagcat gtcacccagt acaacattca aaagtggaat acagtgatac tgactttcaa 60
tcccagaaaa gtcttttata tgatcatgaa aatgccagca ctcttatttt aactcct 117
<210>401
<211>120
<212>DNA
<213> Artificial sequence
<400>401
gctgtaatga gctggcatga gtatttgtgc cacatggctc cacatgcaag tttgaaacag 60
aactaccctg atacttttct ggatgcctct cagctgcacg cttctcagtg gtgttcaaat 120
<210>402
<211>120
<212>DNA
<213> Artificial sequence
<400>402
gcttacaatt acttccagga agactttgtt tatagacctc aggttgcaaa acccctaatc 60
taagcatagc attcaatttt ggccctctgt ttctacctag ttctgcttga atgttttcat 120
<210>403
<211>110
<212>DNA
<213> Artificial sequence
<400>403
gcttagatta ggggttttgc aacctgaggt ctataaacaa agtcttcctg gaagtaattg 60
taagcatcct gaaataaaaa agcaagaata tgaagaagta gttcagactg 110
<210>404
<211>112
<212>DNA
<213> Artificial sequence
<400>404
gctttatgaa gcagtgaaga atgcagcaga cccagcttac cttgaggtga gagagtaaga 60
ggacatataa tgaggcttga tgattattca aggtgagaag ctgttttaga ct 112
<210>405
<211>116
<212>DNA
<213> Artificial sequence
<400>405
ggaaaatggg tagttagcta tttctgtaag tataatacta tttctcccct cctcccttta 60
acacctcaga attgcatttt tacacctaac gtttaacacc taaggttttt gctgat 116
<210>406
<211>104
<212>DNA
<213> Artificial sequence
<400>406
ggaactaacc aaacggagca gaatggtcaa gtgatgaata ttactaatag tggtcatgag 60
aataaaacaa aaggtgattc tattcagaat gagaaaaatc ctaa 104
<210>407
<211>120
<212>DNA
<213> Artificial sequence
<400>407
ggaagccatt gtcctctgtc caggcatctg gctgcacaac cacaattggg tggacaccct 60
ggatccccag gaaggaaaga gcattcaaag tgtcaaagta ggactactgg aactgtcact 120
<210>408
<211>120
<212>DNA
<213> Artificial sequence
<400>408
ggagacaatg aaccacaaac aattgtgcca ttaattcaaa gagatgatgt cagcaaacct 60
aagaatgtgg gatacatact actgaatgca aaggacacca cacacacgca tgtgcacaca 120
<210>409
<211>111
<212>DNA
<213> Artificial sequence
<400>409
ggagttggtc tgagtgacaa ggaattggtt tcagatgatg aagaaagagg aacgggcttg 60
gaagaaaata atcaagaaga gcaaagcatg gattcaaact taggtattgg a 111
<210>410
<211>120
<212>DNA
<213> Artificial sequence
<400>410
ggattttttt tttaaataga tttaggacca ataagtctta attggtttga agaactttct 60
tcagaagctc caccctataa ttctgaacct gcagaagaat ctgaacataa aaacaacaat 120
<210>411
<211>115
<212>DNA
<213> Artificial sequence
<400>411
ggcaacatac catcttcaac ctctgcattg aaagttcccc aattgaaagt tgcagaatct 60
gcccagagtc cagctgctgc tcatactact gatactgctg ggtataatgc aatgg 115
<210>412
<211>116
<212>DNA
<213> Artificial sequence
<400>412
ggcctttctg ctgacaagtt tgaggtgtct gcagatagtt ctaccagtaa aaataaagaa 60
ccaggagtgg aaaggtaaga aacatcaatg taaagatgct gtggtatctg acatct 116
<210>413
<211>115
<212>DNA
<213> Artificial sequence
<400>413
gggaaacaag catagaaatg gaagaaagtg aacttgatgc tcagtatttg cagaatacat 60
tcaaggtttc aaagcgccag tcatttgctc cgttttcaaa tccaggaaat gcaga 115
<210>414
<211>120
<212>DNA
<213> Artificial sequence
<400>414
ggtaaatatt ctacctggtt tatttttatg acttagtaat tgagaatttg acaatagcgt 60
tatacctttg ccctgagatt tacaaatctg tacctagcat tctgcctcat acaggcaatt 120
<210>415
<211>112
<212>DNA
<213> Artificial sequence
<400>415
ggtccttaaa gaaacaaagt ccaaaagtca cttttgaatg tgaacaaaag gaagaaaatc 60
aaggaaagaa tgagtctaat atcaagcctg tacagacagt taatatcact gc 112
<210>416
<211>120
<212>DNA
<213> Artificial sequence
<400>416
ggtcttctgt tttgcagact tatttaccaa gcattggagg aatatcgtag gtaaaaatgc 60
ctattggatc caaagagagg ccaacatttt ttgaaatttt taagacacgc tgcaacaaag 120
<210>417
<211>107
<212>DNA
<213> Artificial sequence
<400>417
ggtgaaataa aggaagatac tagttttgct gaaaatgaca ttaaggaaag ttctgctgtt 60
tttagcaaaa gcgtccagaa aggagagctt agcaggagtc ctagccc 107
<210>418
<211>120
<212>DNA
<213> Artificial sequence
<400>418
ggtgagagag taagaggaca tataatgagg cttgatgatt attcaaggtg agaagctgtt 60
ttagactctc tggccatcac aggaaggagt atgttgaaat gctgcatttc tcaaaaggga 120
<210>419
<211>120
<212>DNA
<213> Artificial sequence
<400>419
ggtgatgttc ctgagatgcc tttgccaata ttacctggtt actgcagtca tttaagctat 60
tcttcaatga taataaattc tcctctgtgt tcttagacag acactcggta gcaacggtgc 120
<210>420
<211>105
<212>DNA
<213> Artificial sequence
<400>420
ggtgccattt atcgtttttg aagcagaggg ataccatgca acataacctg ataaagctcc 60
agcaggaaat ggctgaacta gaagctgtgt tagaacagcatggga 105
<210>421
<211>120
<212>DNA
<213> Artificial sequence
<400>421
gtaaaaatag tcatataacc cctcagatgt tattttccaa gcaggatttt aattcaaacc 60
ataatttaac acctagccaa aaggcagaaa ttacagaact ttctactata ttagaagaat 120
<210>422
<211>120
<212>DNA
<213> Artificial sequence
<400>422
gtaacagtag catgtctaac agctattcct accattctga tgaggtatat aatgattcag 60
gatatctctc aaaaaataaa cttgattctg gtattgagcc agtattgaag aatgttgaag 120
<210>423
<211>120
<212>DNA
<213> Artificial sequence
<400>423
gtaagtattt ttgtttaaca tttaaagagt caatacttta gctttaaaaa aatggtctat 60
agacttttga gaaataaaac tgatattatt tgccttaaaa acatatatga aatatttctt 120
<210>424
<211>120
<212>DNA
<213> Artificial sequence
<400>424
gtaagtgttc atttttacct ttcgtgttgc caatcactat ttttaaagtg tttattcagt 60
agacttggta tgctaacaat taagagtgtt ataaactatg tcttttcagc catttttgtg 120
<210>425
<211>120
<212>DNA
<213> Artificial sequence
<400>425
gtaataagtc ttacaaaatg aagcggccca tctctgcaaa ggggagtgga atacagagtg 60
gtggggtgag atttttgtca acttgaggga gggagcttta cctttctgtc ctgggattct 120
<210>426
<211>120
<212>DNA
<213> Artificial sequence
<400>426
gtaatacttc aaataaagaa cagttaactg ctactaaaac ggagcaaaat ataaaagatt 60
ttgagacttc tgatacattt tttcagactg caagtgggaa aaatattagt gtcgccaaag 120
<210>427
<211>120
<212>DNA
<213> Artificial sequence
<400>427
gtacactgct caaatcattc ctggtacagg aaacaagctt ctggtaagtt aatgtaaact 60
caaggaatat tataagaagt atatatggag gccatcgtat attctgttgt atacctagta 120
<210>428
<211>120
<212>DNA
<213> Artificial sequence
<400>428
gtagacaaac tgaaaatctc aaaacatcaa aaagtatctt tttgaaagtt aaagtacatg 60
aaaatgtaga aaaagaaaca gcaaaaagtc ctgcaacttg ttacacaaat cagtcccctt 120
<210>429
<211>120
<212>DNA
<213> Artificial sequence
<400>429
gtagttaatg aaaatttttg gtaaattcag ttttggtttg ttataattgt ttttattgtg 60
tgatacatgt ttactttaaa ttgtttttct tttttgtgtg tgtttatttt gtgtagctgt 120
<210>430
<211>120
<212>DNA
<213> Artificial sequence
<400>430
gtatagggaa gcttcataag tcagtctcat ctgcaaatac ttgtgggatt tttagcacag 60
caagtggaaa atctgtccag gtatcagatg cttcattaca aaacgcaaga caagtgtttt 120
<210>431
<211>120
<212>DNA
<213> Artificial sequence
<400>431
gtatggtaaa gaacagtcaa gcaattgttg gccagttctg tgcttttcct cctgaagaga 60
aacttgacac catggacaaa ataaattgac catcatcagt cagctaacat gtatgatgcc 120
<210>432
<211>120
<212>DNA
<213> Artificial sequence
<400>432
gtatgtaagg tcaattctgt tcatttgcat aggagataat cataggaatc ccaaattaat 60
acactcttgt gctgacttac cagatgggac actctaagat tttctgcata gcattaatga 120
<210>433
<211>120
<212>DNA
<213> Artificial sequence
<400>433
gtatttattc tttgatagat ttaattacaa gtcttcagaa tgccagagat atacaggata 60
tgcgaattaa gaagaaacaa aggcaacgcg tctttccaca gccaggcagt ctgtatcttg 120
<210>434
<211>130
<212>DNA
<213> Artificial sequence
<400>434
gtattttaca gatgcaaaca gctataattt tgcaaaaaag gaaaataact ctcctgaaca 60
tctaaaagat gaagtttcta tcatccaaag tatgggctac agaaaccgtg ccaaaagact 120
tctacagagt 130
<210>435
<211>119
<212>DNA
<213> Artificial sequence
<400>435
gtcacagggt tatttcagtg aagagcagtt aagagccttg aataatcaca ggcaaatgtt 60
gaatgataag aaacaagctc agatccagtt ggaaattagg aaggccatgg aatctgctg 119
<210>436
<211>115
<212>DNA
<213> Artificial sequence
<400>436
gtcagtagaa atctaagccc acctaattgt actgaattgc aaattgatag ttgttctagc 60
agtgaagaga taaagaaaaa aaagtacaac caaatgccag tcaggcacag cagaa 115
<210>437
<211>120
<212>DNA
<213> Artificial sequence
<400>437
gtccagtttc gttgcctctg aactgagatg atagacaaaa cctagagcct cctttgatac 60
tacatttggc attatcaact ggcttatctt tctgaccaac cacaggaaag cctgcagtga 120
<210>438
<211>111
<212>DNA
<213> Artificial sequence
<400>438
gtctaaatct catttgtatg aacatctgac tttggaaaaa tcttcaagca atttagcagt 60
ttcaggacat ccattttatc aagtttctgc tacaagaaat gaaaaaatga g 111
<210>439
<211>117
<212>DNA
<213> Artificial sequence
<400>439
gtctgtcact ggttaaaact aaggtgggat ttttttttta aatagattta ggaccaataa 60
gtcttaattg gtttgaagaa ctttcttcag aagctccacc ctataattct gaacctg 117
<210>440
<211>111
<212>DNA
<213> Artificial sequence
<400>440
gtcttaaaga atggcagact gacagttggt cagaagatta ttcttcatgg agcagaactg 60
gtgggctctc ctgatgcctg tacacctctt gaagccccag aatctcttat g 111
<210>441
<211>120
<212>DNA
<213> Artificial sequence
<400>441
gtcttaaaga atggcagact gacagttggt cagaagatta ttcttcatgg agcagaactg 60
gtgggctctc ctgatgcctg tacacctctt gaagccccag aatctcttat gttaaaggta 120
<210>442
<211>123
<212>DNA
<213> Artificial sequence
<400>442
gtcttcagaa tgccagagat atacaggata tgcgaattaa gaagaaacaa aggcaacgcg 60
tctttccaca gccaggcagt ctgtatcttg caaaaacatc cactctgcct cgaatctctc 120
tga 123
<210>443
<211>113
<212>DNA
<213> Artificial sequence
<400>443
gtctttgttc caccttttaa aactaaatca cattttcaca gagttgaaca gtgtgttagg 60
aatattaact tggaggaaaa cagacaaaag caaaacattg atggacatgg ctc 113
<210>444
<211>120
<212>DNA
<213> Artificial sequence
<400>444
gtgaaaaatc taaaaaccaa gtgaaagaaa aatactcatt tgtatctgaa gtggaaccaa 60
atgatactga tccattagat tcaaatgtag caaatcagaa gccctttgag agtggaagtg 120
<210>445
<211>117
<212>DNA
<213> Artificial sequence
<400>445
gtgaaaacta aaatggatca agcagatgat gtttcctgtc cacttctaaa ttcttgtctt 60
agtgaaaggt atgatgaagc tattatatta aaatatttaa atgaaacatt ttcctac 117
<210>446
<211>120
<212>DNA
<213> Artificial sequence
<400>446
gtgaagagca gttaagagcc ttgaataatc acaggcaaat gttgaatgat aagaaacaag 60
ctcagatcca gttggaaatt aggaaggcca tggaatctgc tgaacaaaag gaacaaggtt 120
<210>447
<211>120
<212>DNA
<213> Artificial sequence
<400>447
gtgagccact gtgcctggcc aggggttgtg ctttttaaat ttcaatttta tttttgctaa 60
gtatttattc tttgatagat ttaattacaa gtcttcagaa tgccagagat atacaggata 120
<210>448
<211>120
<212>DNA
<213> Artificial sequence
<400>448
gtgagccact gtgcctggcc tgatacaatt aacttgaatg ttatatatgt gacttttttg 60
gtgtgtgtaa cacattatta cagtggatgg agaagacatc atctggatta tacatatttc 120
<210>449
<211>120
<212>DNA
<213> Artificial sequence
<400>449
gtgctacact gtccaacacc cactctcggg tcaccacagg tgcctcacac atctgcccaa 60
ttgctggaga cagagaacac aagcagagat tagtgtcaat tcattctcct ggactaggct 120
<210>450
<211>106
<212>DNA
<213> Artificial sequence
<400>450
gtggagccat gtggcacaaa tactcatgcc agctcattac agcatgagaa cagcagttta 60
ttactcacta aagacagaat gaatgtagaa aaggctgaat tctgta 106
<210>451
<211>120
<212>DNA
<213> Artificial sequence
<400>451
gtgggctctc ctgatgcctg tacacctctt gaagccccag aatctcttat gttaaaggta 60
aattaatttg cactcttggt aaaaatcagt cattgattca gttaaattct agaagtttta 120
<210>452
<211>120
<212>DNA
<213> Artificial sequence
<400>452
gtggggtgag atttttgtca acttgaggga gggagcttta cctttctgtc ctgggattct 60
cttgctcgct ttggaccttg gtggtttctt ccattgacca catctcctct gacttcaaaa 120
<210>453
<211>121
<212>DNA
<213> Artificial sequence
<400>453
gtgtaaactc agaaatggaa aaaacctgca gtaaagaatt taaattatca aataacttaa 60
atgttgaagg tggttcttca gaaaataatc actctattaa agtttctcca tatctctctc 120
a 121
<210>454
<211>120
<212>DNA
<213> Artificial sequence
<400>454
gtgtaatttt atttcattaa ctagtatcta caaatggctt tgtttaaaga atgaacacat 60
tagtgcagga atggatgaat gaaatcatca tattttctaa ttagcctgca gtggcagcct 120
<210>455
<211>116
<212>DNA
<213> Artificial sequence
<400>455
gtgtctgtct aagaacacag aggagaattt attatcattg aagaatagct taaatgactg 60
cagtaaccag gtaatattgg caaaggcatc tcaggaacat caccttagtg aggaaa 116
<210>456
<211>120
<212>DNA
<213> Artificial sequence
<400>456
gtgtgtgtaa cacattatta cagtggatgg agaagacatc atctggatta tacatatttc 60
gcaatgaaag agaggaagaa aaggaagcag caaaatatgt ggaggcccaa caaaagagac 120
<210>457
<211>120
<212>DNA
<213> Artificial sequence
<400>457
gtgttttctg gcaaacttgt acacgagcat ctgaaattaa atcaaatatt ccattatcat 60
gagttacctc tagcacacag ctcagaatac tagttattcc accatggcat atgtttacct 120
<210>458
<211>120
<212>DNA
<213> Artificial sequence
<400>458
gttcaagcgc atgaatatgc ctggtagaag acttcctcct cagcctattc tttttaggtg 60
cttttgaatt gtggatattt aattcgagtt ccatattgct tatactgctg cttataggtt 120
<210>459
<211>120
<212>DNA
<213> Artificial sequence
<400>459
gttcacattc aaaagtgact tttggacttt gtttctttaa ggacccagag tgggcagaga 60
atgttgcaca ttcctcttct gcatttcctg gatttgaaaa cggagcaaat gactggcgct 120
<210>460
<211>120
<212>DNA
<213> Artificial sequence
<400>460
gttcttcaga aaataatcac tctattaaag tttctccata tctctctcaa tttcaacaag 60
acaaacaaca gttggtatta ggaaccaaag tgtcacttgt tgagaacatt catgttttgg 120
<210>461
<211>120
<212>DNA
<213> Artificial sequence
<400>461
gttggatttt tcgttctcac ttaattgaag aaagtaaagc ttctataaag ttaggtgttt 60
cctgggttat gaaggacaaa aacaaaagct aataatggag ccacataaca cattcaaact 120
<210>462
<211>122
<212>DNA
<213> Artificial sequence
<400>462
gttgttgatg tggaggagca acagctggaa gagtctgggc cacacgattt gacggaaaca 60
tcttacttgc caaggcaaga tctaggtaat atttcatctg ctgtattgga acaaacactt 120
tg 122
<210>463
<211>120
<212>DNA
<213> Artificial sequence
<400>463
gtttagcttg tgttgaaatt gtaaatacct tggcattaga taatcaaaag aaactgagca 60
agcctcagtc aattaatact gtatctgcac atttacagag tagtgtagtt gtttctgatt 120
<210>464
<211>112
<212>DNA
<213> Artificial sequence
<400>464
gttttcactt ttagatatga tacggaaatt gatagaagca gaagatcggc tataaaaaag 60
ataatggaaa gggatgacac agctgcaaaa acacttgttc tctgtgtttc tg 112
<210>465
<211>118
<212>DNA
<213> Artificial sequence
<400>465
taaaaatgga aattggtaaa actgaaactt tttctgatgt tcctgtgaaa acaaatatag 60
aagtttgttc tacttactcc aaagattcag aaaactactt tgaaacagaa gcagtaga 118
<210>466
<211>109
<212>DNA
<213> Artificial sequence
<400>466
taaagaagca aaatgtaata aggaaaaact acagttattt attaccccag aagctgattc 60
tctgtcatgc ctgcaggaag gacagtgtga aaatgatcca aaaagcaaa 109
<210>467
<211>120
<212>DNA
<213> Artificial sequence
<400>467
taaatatgac attgattaga ctgttgaaat tgctaacaat tttggaatgc cttgttaaat 60
tatttatctt acatttttaa tttcctaatc tgtaatttat ctaagccttt gagaaagtct 120
<210>468
<211>115
<212>DNA
<213> Artificial sequence
<400>468
taaattatct ggccagttta tgaaggaggg aaacactcag attaaagaag atttgtcaga 60
tttaactttt ttggaagttg cgaaagctca agaagcatgt catggtaata cttca 115
<210>469
<211>112
<212>DNA
<213> Artificial sequence
<400>469
taaattgttt ttcttttttg tgtgtgttta ttttgtgtag ctgtatacgt atggcgtttc 60
taaacattgc ataaaaatta acagcaaaaa tgcagagtct tttcagtttc ac 112
<210>470
<211>120
<212>DNA
<213> Artificial sequence
<400>470
taacccttta aatactgata tgtaatattt agcacattct acataaactg tttctatgag 60
aaaggttgtg agaataatat aaattatatg gcttataaaa tattaatgtg cttctgtttt 120
<210>471
<211>120
<212>DNA
<213> Artificial sequence
<400>471
taactaccca ttttcctccc gcaattccta gaaaatattt cagtgtccgttcacacacaa 60
actcagcatc tgcagaatga aaaacactca aaggattaga agttgaaaac aaaatcagga 120
<210>472
<211>113
<212>DNA
<213> Artificial sequence
<400>472
taagagtaat ccaaaaaaat caagaagaaa ctacttcaat ttcaaaaata actgtcaatc 60
cagactctga agaacttttc tcagacaatg agaataattt tgtcttccaa gta 113
<210>473
<211>120
<212>DNA
<213> Artificial sequence
<400>473
taagcatagc attcaatttt ggccctctgt ttctacctag ttctgcttga atgttttcat 60
cactggaacc tatttcatta atactggagc ccacttcatt agtactggaa cctacttcat 120
<210>474
<211>120
<212>DNA
<213> Artificial sequence
<400>474
taatattgct tgagctggct tctttaaaaa cattttctct aatgttatta cggctaattg 60
tgctcactgt acttggaatg ttctcatttc ccatttctct ttcaggtgac attgaatgtt 120
<210>475
<211>120
<212>DNA
<213> Artificial sequence
<400>475
taatctctca ggatcttgattataaagaag caaaatgtaa taaggaaaaa ctacagttat 60
ttattacccc agaagctgat tctctgtcat gcctgcagga aggacagtgt gaaaatgatc 120
<210>476
<211>120
<212>DNA
<213> Artificial sequence
<400>476
taattaccca tgtgctgagc aaggatcata aaatgttgga gctaggtcct tactcttcag 60
aaggagataa aggggaagga aagaattttg cttaagatat cagtgtttgg ccaacaatac 120
<210>477
<211>120
<212>DNA
<213> Artificial sequence
<400>477
tacaacattc aaaagtggaa tacagtgata ctgactttca atcccagaaa agtcttttat 60
atgatcatga aaatgccagc actcttattt taactcctac ttccaaggat gttctgtcaa 120
<210>478
<211>120
<212>DNA
<213> Artificial sequence
<400>478
tacagtcaga aatgaagaag catctgaaac tgtatttcct catgatacta ctgctgtaag 60
taaatatgac attgattaga ctgttgaaat tgctaacaat tttggaatgc cttgttaaat 120
<210>479
<211>120
<212>DNA
<213> Artificial sequence
<400>479
tacatttggc attatcaact ggcttatctt tctgaccaac cacaggaaag cctgcagtga 60
tattaactgt ctgtacaggc ttgatattag actcattctt tccttgattt tcttcctttt 120
<210>480
<211>108
<212>DNA
<213> Artificial sequence
<400>480
tacctggtac tgattatggc actcaggaaa gtatctcgtt actggaagtt agcactctag 60
ggaaggcaaa aacagaacca aataaatgtg tgagtcagtg tgcagcat 108
<210>481
<211>120
<212>DNA
<213> Artificial sequence
<400>481
tacgaaccaa acctatttaa aactccacaa aggaaaccat cttataatca gctggcttca 60
actccaataa tattcaaaga gcaagggctg actctgccgc tgtaccaatc tcctgtaaaa 120
<210>482
<211>120
<212>DNA
<213> Artificial sequence
<400>482
tacgctttaa tttatttgtg aggggacgct cttgtattat ctgtggctca gtaacaaatg 60
ctcctataat tagattttca gttacatggc ttaagttggg gaggcttgcc ttcttccgat 120
<210>483
<211>120
<212>DNA
<213> Artificial sequence
<400>483
tacttccagc ccatctgtta tgttggctcc ttgctaagcc aggctgtttg cttttattac 60
agaattcagc cttttctaca ttcattctgt ctttagtgag taataaactg ctgttctcat 120
<210>484
<211>120
<212>DNA
<213> Artificial sequence
<400>484
tacttgcaaa atatgtggtc acactttgtg gagacaggtt ccttgatcaa ctccagacta 60
gcagggtagg gggggagaaa aagaaaataa atgaggctca ataatttatt taaaaataaa 120
<210>485
<211>120
<212>DNA
<213> Artificial sequence
<400>485
tagaagcctt attcactaaa attcaggagg aatttgaaga acatgaaggt aaaattagtt 60
atatggtaca cattgttatt tctaatatga gaacaaagtc ttagagactt tgaatttaac 120
<210>486
<211>112
<212>DNA
<213> Artificial sequence
<400>486
taggaaaaaa attttccatg aagcaaacgc tgatgaatgt gaaaaatcta aaaaccaagt 60
gaaagaaaaa tactcatttg tatctgaagt ggaaccaaat gatactgatc ca 112
<210>487
<211>120
<212>DNA
<213> Artificial sequence
<400>487
taggattctc tgagcatggc agtttctgct tattccattc ttttctctca cacaggggat 60
cagcattcag atctaccttt ttttctgtgc tgggagtccg cctatcatta catgtttcct 120
<210>488
<211>120
<212>DNA
<213> Artificial sequence
<400>488
taggattgac aaattcttta agttcactgg tatttgaaca cttagtaaaa gaaccaggtg 60
catttgttaa cttcagctct gggaaagtat cgctgtcatg tcttttactt gtctgttcat 120
<210>489
<211>112
<212>DNA
<213> Artificial sequence
<400>489
tagttgtttc tgattgtaaa aatagtcata taacccctca gatgttattt tccaagcagg 60
attttaattc aaaccataat ttaacaccta gccaaaaggc agaaattaca ga 112
<210>490
<211>120
<212>DNA
<213> Artificial sequence
<400>490
tagtttttta tgttactaca taattatgat aggctacgtt ttcatttttt tatcagatgt 60
cttctcctaa ttgtgagata tattatcaaa gtcctttatc actttgtatg gccaaaagga 120
<210>491
<211>120
<212>DNA
<213> Artificial sequence
<400>491
tataaatgcc tgtatgcaaa aaactggaga aagtatggtg aaaaaaatta acaatcagag 60
ttcaatataa ataaagatgt cagataccac agcatcttta cattgatgtt tcttaccttt 120
<210>492
<211>120
<212>DNA
<213> Artificial sequence
<400>492
tatactgcat gcaaatgatc ccaagtggtc caccccaact aaagactgta cttcagggcc 60
gtacactgct caaatcattc ctggtacagg aaacaagctt ctggtaagtt aatgtaaact 120
<210>493
<211>120
<212>DNA
<213> Artificial sequence
<400>493
tatcaaggga tgtcacaacc gtgtggaagt tgcgtattgt aagctattca aaaaaagaaa 60
aagattcagg taagtatgta aatgctttgt ttttatcagt tttattaact taaaaaatga 120
<210>494
<211>120
<212>DNA
<213> Artificial sequence
<400>494
tatctaaaag tagtattcca acaatttata tgaatgagaa tcttctttta aaaataagat 60
aaactagttt ttgccagttt tttaaaataa cctaagggat ttgctttgtt ttattttagt 120
<210>495
<211>120
<212>DNA
<213> Artificial sequence
<400>495
tatgatatct gtaatagaat tgaatacata tttaactact aaatcaatat atttattaat 60
ttgtccagat ttctgctaac agtactcggc ctgctcgctg gtataccaaa cttggattct 120
<210>496
<211>120
<212>DNA
<213> Artificial sequence
<400>496
tatgcctagt agactgagaa ggtatattgt ttactttacc aaataacaag tgttggaagc 60
agggaagctc ttcatcctca ctagataagt tctcttctga ggactctaat ttcttggccc 120
<210>497
<211>120
<212>DNA
<213> Artificial sequence
<400>497
tatgtgcttt aaatgaaaat tataaaaacg ttgagctgtt gccacctgaa aaatacatga 60
gagtagcatc accttcaaga aaggtacaat tcaaccaaaa cacaaatcta agagtaatcc 120
<210>498
<211>120
<212>DNA
<213> Artificial sequence
<400>498
tattaactgt ctgtacaggc ttgatattag actcattctt tccttgattt tcttcctttt 60
gttcacattc aaaagtgact tttggacttt gtttctttaa ggacccagag tgggcagaga 120
<210>499
<211>120
<212>DNA
<213> Artificial sequence
<400>499
tattgggttt tcatacagct agcgggaaaa aagttaaaat tgcaaaggaa tctttggaca 60
aagtgaaaaa cctttttgat gaaaaagagc aaggtactag tgaaatcacc agttttagcc 120
<210>500
<211>118
<212>DNA
<213> Artificial sequence
<400>500
tatttcagaa aaagacctat tagacacaga gaacaaaaga aagaaagatt ttcttacttc 60
agagaattct ttgccacgta tttctagcct accaaaatca gagaagccat taaatgag 118
<210>501
<211>120
<212>DNA
<213> Artificial sequence
<400>501
tcaaaaagtc tatattcaga ataagagaat cacctaaaga gactttcaat gcaagttttt 60
caggtcatat gactgatcca aactttaaaa aagaaactga agcctctgaa agtggactgg 120
<210>502
<211>115
<212>DNA
<213> Artificial sequence
<400>502
tcaaagagca agggctgact ctgccgctgt accaatctcc tgtaaaagaa ttagataaat 60
tcaaattaga cttaggtaag taatgcaata tggtagactg gggagaacta caaac 115
<210>503
<211>119
<212>DNA
<213> Artificial sequence
<400>503
tcaagaaaaa tccttaaagg cttcaaaaag cactccagat ggtaaaatta gctttttatt 60
tatatctgtt ctccctctat aggtatggta tataatattc tgacctcagg tgatccacc 119
<210>504
<211>120
<212>DNA
<213> Artificial sequence
<400>504
tcaattcatt ttgtttcaaa tgtgtcatgt aatcaaatag tagatgtgct ttttgatgtc 60
tgacaaaaaa taagtttttg cattctagtg ataatataca atacacataa atttttatct 120
<210>505
<211>120
<212>DNA
<213> Artificial sequence
<400>505
tcacaggaga gaatattgtg tcctccctct ctgacagggc acccaatact tactgtgcca 60
agggtgaatg atgaaagctc cttcaccaca gaagcaccac acagctgtac catccattcc 120
<210>506
<211>120
<212>DNA
<213> Artificial sequence
<400>506
tcactattca cctacgtcta gacaaaatgt atcaaaaata cttcctcgtg ttgataagag 60
aaacccagag cactgtgtaa actcagaaat ggaaaaaacc tgcagtaaag aatttaaatt 120
<210>507
<211>120
<212>DNA
<213> Artificial sequence
<400>507
tcagaagctc caccctataa ttctgaacct gcagaagaat ctgaacataa aaacaacaat 60
tacgaaccaa acctatttaa aactccacaa aggaaaccat cttataatca gctggcttca 120
<210>508
<211>120
<212>DNA
<213> Artificial sequence
<400>508
tcaggacatc cattttatca agtttctgct acaagaaatg aaaaaatgag acacttgatt 60
actacaggca gaccaaccaa agtctttgtt ccacctttta aaactaaatc acattttcac 120
<210>509
<211>120
<212>DNA
<213> Artificial sequence
<400>509
tcagggctct gtgtgacact ccaggtgtgg atccaaagct tatttctaga atttgggttt 60
ataatcacta tagatggatc atatggaaac tggcagctat ggaatgtgcc tttcctaagg 120
<210>510
<211>120
<212>DNA
<213> Artificial sequence
<400>510
tcatagaaaa gacaggttac atacagcaga agaacgtgct cttttcacgg agatagagag 60
gtcagcgatt cacaaaagag cacaggaaga atgacagagg agaggtcctt ccctctaaag 120
<210>511
<211>119
<212>DNA
<213> Artificial sequence
<400>511
tcatgctgaa agaaaccaaa cacaacccat caggataaga gaaagagaag cttccttcaa 60
tggaagtgga gcagacacgt catatttaag gcattcaggc caggcgcagt ggctcaccc 119
<210>512
<211>120
<212>DNA
<213> Artificial sequence
<400>512
tcatttgttt ggaagaacca atcaagaaag gatcctgggt gtttgtattt gcagtcaagt 60
cttccaattc actgcactgt gaagaaaaca agctagcaga acattttgtt tcctcactaa 120
<210>513
<211>120
<212>DNA
<213> Artificial sequence
<400>513
tccaatcatg atgaaagtct gaagaaaaat gatagattta tcgcttctgt gacagacagt 60
gaaaacacaa atcaaagaga agctgcaagt catggtaagt cctctgttta gttgaactac 120
<210>514
<211>120
<212>DNA
<213> Artificial sequence
<400>514
tccagaatgt tgttaagtct tagtcattag ggagatacat atggatacac tcacaaattc 60
ttctggggtc aggccagaca ccaccatgga cattcttttg ttgacccttt ctgttgaagc 120
<210>515
<211>107
<212>DNA
<213> Artificial sequence
<400>515
tccagttgga aattaggaag gccatggaat ctgctgaaca aaaggaacaa ggtttatcaa 60
gggatgtcac aaccgtgtgg aagttgcgta ttgtaagcta ttcaaaa 107
<210>516
<211>116
<212>DNA
<213> Artificial sequence
<400>516
tccattttag atcaactgga atggatggta cagctgtgtg gtgcttctgt ggtgaaggag 60
ctttcatcat tcacccttgg cacagtaagt attgggtgcc ctgtcagaga gggagg 116
<210>517
<211>120
<212>DNA
<213> Artificial sequence
<400>517
tccccttttt ttacccccag tggtatgtgg gagtttgttt catacaccaa agtttgtgaa 60
ggtaaatatt ctacctggtt tatttttatg acttagtaat tgagaatttg acaatagcgt 120
<210>518
<211>120
<212>DNA
<213> Artificial sequence
<400>518
tccctctgaa aggaatggga gaagtttaat ttacacaacg atgaatgttg aattacaaag 60
ttctggtctc tgttaagaat taaaaagacc aataaagtta ggttaagaga aaaatgggta 120
<210>519
<211>120
<212>DNA
<213> Artificial sequence
<400>519
tctaaatctc atttgtatga acatctgact ttggaaaaat cttcaagcaa tttagcagtt 60
tcaggacatc cattttatca agtttctgct acaagaaatg aaaaaatgag acacttgatt 120
<210>520
<211>120
<212>DNA
<213> Artificial sequence
<400>520
tctaagcatt tgcaaaggcg acaataaatt attgacgctt aacctttcca gtttataaga 60
ctggaatata atttcaaacc acacattagt acttatgttg cacaatgaga aaagaaatta 120
<210>521
<211>119
<212>DNA
<213> Artificial sequence
<400>521
tctccaaaca gttatactga gtatttggcg tccatcatca gatttatatt ctctgttaac 60
agaaggaaag agatacagaa tttatcatct tgcaacttca aaatctaaaa gtaaatctg 119
<210>522
<211>120
<212>DNA
<213> Artificial sequence
<400>522
tctcccacac tatagggaaa agacagagtc ctaataagaa acactagtta catgtatgca 60
gaactgtcaa atgaccaaga tcaaacattt tagctctttc gattacagaa agctgaccaa 120
<210>523
<211>123
<212>DNA
<213> Artificial sequence
<400>523
tctctcttcc tctcttcttc cagatcttca gggggctaga aatctgttgc tatgggccct 60
tcaccaacat gcccacaggt aagagcctgg gagaacccca gagttccagc accagccttt 120
gtc 123
<210>524
<211>120
<212>DNA
<213> Artificial sequence
<400>524
tctgctagtc caaaagaggg ccactttcaa gagacattca acaaaatgaa aaatactgtt 60
gaggtaaggt tacttttcag catcaccaca cattttggta tttttctatt ttgacagtcc 120
<210>525
<211>111
<212>DNA
<213> Artificial sequence
<400>525
tctgctcatg gcacaaaact gaatgtttct actgaagctc tgcaaaaagc tgtgaaactg 60
tttagtgata ttgagaatat tagtgaggaa acttctgcag aggtacatcc a 111
<210>526
<211>117
<212>DNA
<213> Artificial sequence
<400>526
tctgtatctt gcaaaaacat ccactctgcc tcgaatctct ctgaaagcag cagtaggagg 60
ccaagttccc tctgcgtgtt ctcataaaca ggtatgtgtt tgtctacaat actgatg 117
<210>527
<211>119
<212>DNA
<213> Artificial sequence
<400>527
tctgttgttt caatgtttaa gatagaaaat cataatgata aaactgtaag tgaaaaaaat 60
aataaatgcc aactgatatt acaaaataat attgaaatga ctactggcac ttttgttga 119
<210>528
<211>120
<212>DNA
<213> Artificial sequence
<400>528
tcttaaaatt catctaacac atctataata acattctttt cttttttttc cattctagga 60
cttgcccctt tcgtctattt gtcagacgaa tgttacaatt tactggcaat aaagttttgg 120
<210>529
<211>122
<212>DNA
<213> Artificial sequence
<400>529
tcttagaaaa cacaacaaaa ccatatttac catcacgtgc actaacaaga cagcaagttc 60
gtgctttgca agatggtgca gagctttatg aagcagtgaa gaatgcagca gacccagctt 120
ac 122
<210>530
<211>120
<212>DNA
<213> Artificial sequence
<400>530
tcttcaatga taataaattc tcctctgtgt tcttagacag acactcggta gcaacggtgc 60
tatgcctagt agactgagaa ggtatattgt ttactttacc aaataacaag tgttggaagc 120
<210>531
<211>119
<212>DNA
<213> Artificial sequence
<400>531
tcttcagaaa ataatcactc tattaaagtt tctccatatc tctctcaatt tcaacaagac 60
aaacaacagt tggtattagg aaccaaagtg tcacttgttg agaacattca tgttttggg 119
<210>532
<211>120
<212>DNA
<213> Artificial sequence
<400>532
tcttcctaag actttttaaa gtgaatattt ttaaggcagt tctagaagaa tgaaaactct 60
tatgatatct gtaatagaat tgaatacata tttaactact aaatcaatat atttattaat 120
<210>533
<211>124
<212>DNA
<213> Artificial sequence
<400>533
tctttagggg tgacccagtc tattaaagaa agaaaaatgc tgaatgaggt aagtacttga 60
tgttacaaac taaccagaga tattcattca gtcatatagt taaaaatgta tttgcttcct 120
tcca 124
<210>534
<211>120
<212>DNA
<213> Artificial sequence
<400>534
tctttgactc acctgcaata agttgcctta ttaacggtat cttcagaaga atcagatcct 60
aaaaaatttc cccccaaaaa ataaatcaat aaaagttttc ttaattaaaa gggttaaaaa 120
<210>535
<211>116
<212>DNA
<213> Artificial sequence
<400>535
tgaagaactt tcttcagaag ctccacccta taattctgaa cctgcagaag aatctgaaca 60
taaaaacaac aattacgaac caaacctatt taaaactcca caaaggaaac catctt 116
<210>536
<211>120
<212>DNA
<213> Artificial sequence
<400>536
tgacaaaaaa taagtttttg cattctagtg ataatataca atacacataa atttttatct 60
tacagtcaga aatgaagaag catctgaaac tgtatttcct catgatacta ctgctgtaag 120
<210>537
<211>121
<212>DNA
<213> Artificial sequence
<400>537
tgacattcag agtgaagaaa ttttacaaca taaccaaaat atgtctggat tggagaaagt 60
ttctaaaata tcaccttgtg atgttagttt ggaaacttca gatatatgta aatgtagtat 120
a 121
<210>538
<211>112
<212>DNA
<213> Artificial sequence
<400>538
tgactcttct gcccttgagg acctgcgaaa tccagaacaa agcacatcag aaaaaggtgt 60
gtattgttgg ccaaacactg atatcttaag caaaattctt tccttcccct tt 112
<210>539
<211>92
<212>DNA
<213> Artificial sequence
<400>539
tgactttttt ggtgtgtgta acacattatt acagtggatg gagaagacat catctggatt 60
atacatattt cgcaatgaaa gagaggaaga aa 92
<210>540
<211>120
<212>DNA
<213> Artificial sequence
<400>540
tgagtcagac ttcattactt gaagcaaaaa aatggcttag agaaggaata tttgatggtc 60
aaccagaaag aataaatact gcagattatg taggaaatta tttgtatgaa aataattcaa 120
<210>541
<211>120
<212>DNA
<213> Artificial sequence
<400>541
tgatacatgt ttactttaaa ttgtttttct tttttgtgtg tgtttatttt gtgtagctgt 60
atacgtatgg cgtttctaaa cattgcataa aaattaacag caaaaatgca gagtcttttc 120
<210>542
<211>120
<212>DNA
<213> Artificial sequence
<400>542
tgatcctcat tatcatggaa aatttgtgca ttgttaagga aagtggtgca ttgatggaag 60
gaagcaaata catttttaac tatatgactg aatgaatatc tctggttagt ttgtaacatc 120
<210>543
<211>120
<212>DNA
<213> Artificial sequence
<400>543
tgcaattctg aggtgttaaa gggaggaggg gagaaatagt attatactta cagaaatagc 60
taactaccca ttttcctccc gcaattccta gaaaatattt cagtgtccgt tcacacacaa 120
<210>544
<211>120
<212>DNA
<213> Artificial sequence
<400>544
tgcgaattaa gaagaaacaa aggcaacgcg tctttccaca gccaggcagt ctgtatcttg 60
caaaaacatc cactctgcct cgaatctctc tgaaagcagc agtaggaggc caagttccct 120
<210>545
<211>120
<212>DNA
<213> Artificial sequence
<400>545
tgctcactgt acttggaatg ttctcatttc ccatttctct ttcaggtgac attgaatgtt 60
cctcaaagtt ttcctctagc agatttttct tacatttagt tttaacaaat gacttgatgg 120
<210>546
<211>120
<212>DNA
<213> Artificial sequence
<400>546
tgcttgtttc ccgactgtgg ttaacttcat gtcccaatgg atacttaaag ccttctgtgt 60
catttctatt atctttggaa caaccatgaa ttagtccctt ggggttttca aatgctgcac 120
<210>547
<211>113
<212>DNA
<213> Artificial sequence
<400>547
tggactggaa aaggaataca gttggctgat ggtggatggc tcataccctc caatgatgga 60
aaggctggaa aagaagaatt ttataggtac tctatgcaaa aagattgtgt gtt 113
<210>548
<211>120
<212>DNA
<213> Artificial sequence
<400>548
tggatcaagc agatgatgtt tcctgtccac ttctaaattc ttgtcttagt gaaaggtatg 60
atgaagctat tatattaaaa tatttaaatg aaacattttc ctacatatat ttgttctata 120
<210>549
<211>120
<212>DNA
<213> Artificial sequence
<400>549
tggcaaaact ataagataag gaatccagca attattatta aatacttaaa aaacctgaga 60
cccttaccca attcaatgta gacagacgtc ttttgaggtt gtatccgctg ctttgtcctc 120
<210>550
<211>120
<212>DNA
<213> Artificial sequence
<400>550
tggcgaccag aatccaaatc aggccttctt actttatttg ctggagattt ttctgtgttt 60
tctgctagtc caaaagaggg ccactttcaa gagacattca acaaaatgaa aaatactgtt 120
<210>551
<211>120
<212>DNA
<213> Artificial sequence
<400>551
tggctgatgg tggatggctc ataccctcca atgatggaaa ggctggaaaa gaagaatttt 60
ataggtactc tatgcaaaaa gattgtgtgt taacttttat gtattccctc atccctcttt 120
<210>552
<211>120
<212>DNA
<213> Artificial sequence
<400>552
tgtagaagtc ttttggcacg gtttctgtag cccatacttt ggatgataga aacttcatct 60
tttagatgtt caggagagtt attttccttt tttgcaaaat tatagctgtt tgcatctgta 120
<210>553
<211>120
<212>DNA
<213> Artificial sequence
<400>553
tgtcaattaa aaaagatttg gtttatgttc ttgcagagga gaacaaaaat agtgtaaagc 60
agcatataaa aatgactcta ggtcaagatt taaaatcgga catctccttg aatatagata 120
<210>554
<211>120
<212>DNA
<213> Artificial sequence
<400>554
tgtcaattct ggcttctccc tgctcacact ttcttccatt gcattatacc cagcagtatc 60
agtagtatga gcagcagctg gactctgggc agattctgca actttcaatt ggggaacttt 120
<210>555
<211>115
<212>DNA
<213> Artificial sequence
<400>555
tgtccatggt gtcaagtttc tcttcaggag gaaaagcaca gaactggcca acaattgctt 60
gactgttctt taccatactg tttagcagga aaccagtctc agtgtccaac tctct 115
<210>556
<211>120
<212>DNA
<213> Artificial sequence
<400>556
tgtcttggtc aagttcttta gctacaccac ccacccttag ttctactgtg ctcataggta 60
ataatagcaa atgtgtattt acaagaaaga gcagatgagg ttgataattg tcatctctaa 120
<210>557
<211>120
<212>DNA
<213> Artificial sequence
<400>557
tgtgacagac agtgaaaaca caaatcaaag agaagctgca agtcatggta agtcctctgt 60
ttagttgaac tacaggtttt tttgttgttg ttgttttgattttttttttt tgaggtggag 120
<210>558
<211>120
<212>DNA
<213> Artificial sequence
<400>558
tgtgattgat ggtactttaa ttttgtcact ttgtgttttt atgtttaggt ttattgcatt 60
cttctgtgaa aagaagctgt tcacagaatg attctgaaga accaactttg tccttaacta 120
<210>559
<211>116
<212>DNA
<213> Artificial sequence
<400>559
tgtgtttctg acataatttc attgagcgca aatatatctg aaacttctag caataaaact 60
agtagtgcag atacccaaaa agtggccatt attgaactta cagatgggtg gtatgc 116
<210>560
<211>120
<212>DNA
<213> Artificial sequence
<400>560
tgtttaatta atatgcctta acaaaagtaa tccatagtca agatcttaag catttttttc 60
cttatgatct ttaactgttc tgggtcacaa atttgtctgt cactggttaa aactaaggtg 120
<210>561
<211>119
<212>DNA
<213> Artificial sequence
<400>561
tgtttttatg tttaggttta ttgcattctt ctgtgaaaag aagctgttca cagaatgatt 60
ctgaagaacc aactttgtcc ttaactagct cttttgggac aattctgagg aaatgttct 119
<210>562
<211>123
<212>DNA
<213> Artificial sequence
<400>562
tgtttttgtt atttaaggtg aagcagcatc tgggtgtgag agtgaaacaa gcgtctctga 60
agactgctca gggctatcct ctcagagtga cattttaacc actcaggtaa aaagcgtgtg 120
tgt 123
<210>563
<211>120
<212>DNA
<213> Artificial sequence
<400>563
ttaaaggaaa tacttttgga aacataaata tgtgggtttg caatttataa agcagctttt 60
ccacttattt tcttagaata ttgacatact ttgcaatgaa gcagaaaaca agcttatgca 120
<210>564
<211>110
<212>DNA
<213> Artificial sequence
<400>564
ttaaagttca ttggaacaga aagaaatgga tttatctgct cttcgcgttg aagaagtaca 60
aaatgtcatt aatgctatgc agaaaatctt agagtgtccc atctggtaag 110
<210>565
<211>119
<212>DNA
<213> Artificial sequence
<400>565
ttaaggaaaa caacgagaat aaatcaaaaa tttgccaaac gaaaattatg gcaggttgtt 60
acgaggcatt ggatgattca gaggatattc ttcataactc tctagataat gatgaatgt 119
<210>566
<211>113
<212>DNA
<213> Artificial sequence
<400>566
ttagcaggaa accagtctca gtgtccaact ctctaacctt ggaactgtga gaactctgag 60
gacaaagcag cggatacaac ctcaaaagac gtctgtctac attgaattgg gta 113
<210>567
<211>125
<212>DNA
<213> Artificial sequence
<400>567
ttaggactct gtcttttccc tatagtgtgg gagatcaaga attgttacaa atcacccctc 60
aaggaaccag ggatgaaatc agtttggatt ctgcaaaaaa gggtaatggc aaagtttgcc 120
aactt 125
<210>568
<211>120
<212>DNA
<213> Artificial sequence
<400>568
ttaggtattg tatgacaatt tgtgtgatga atttttgcct ttcagttaga tatttccgtt 60
gttaaataat gtcctgatgg ttttccccct ttggtggtgg taattttaaa gcccttttta 120
<210>569
<211>120
<212>DNA
<213> Artificial sequence
<400>569
ttagtgatat tgagaatatt agtgaggaaa cttctgcaga ggtacatcca ataagtttat 60
cttcaagtaa atgtcatgat tctgttgttt caatgtttaa gatagaaaat cataatgata 120
<210>570
<211>126
<212>DNA
<213> Artificial sequence
<400>570
ttatagattt tgcatgctga aacttctcaa ccagaagaaa gggccttcac agtgtccttt 60
atgtaagaat gatataacca aaaggtatat aatttggtaa tgatgctagg ttggaagcaa 120
ccacag 126
<210>571
<211>114
<212>DNA
<213> Artificial sequence
<400>571
ttatatgatc atgaaaatgc cagcactctt attttaactc ctacttccaa ggatgttctg 60
tcaaacctag tcatgatttc tagaggcaaa gaatcataca aaatgtcaga caag 114
<210>572
<211>108
<212>DNA
<213> Artificial sequence
<400>572
ttattaattt gtccagattt ctgctaacag tactcggcct gctcgctggt ataccaaact 60
tggattcttt cctgacccta gaccttttcc tctgccctta tcatcgct 108
<210>573
<211>120
<212>DNA
<213> Artificial sequence
<400>573
ttattacccc agaagctgat tctctgtcat gcctgcagga aggacagtgt gaaaatgatc 60
caaaaagcaa aaaagtttca gatataaaag aagaggtctt ggctgcagca tgtcacccag 120
<210>574
<211>120
<212>DNA
<213> Artificial sequence
<400>574
ttatttgttc agggctctgt gtgacactcc aggtgtggat ccaaagctta tttctagaat 60
ttgggtttat aatcactata gatggatcat atggaaactg gcagctatgg aatgtgcctt 120
<210>575
<211>122
<212>DNA
<213> Artificial sequence
<400>575
ttatttttgt atattttcag ctgcttgtga attttctgag acggatgtaa caaatactga 60
acatcatcaa cccagtaata atgatttgaa caccactgag aagcgtgcag ctgagaggca 120
tc 122
<210>576
<211>120
<212>DNA
<213> Artificial sequence
<400>576
ttcaatataa ataaagatgt cagataccac agcatcttta cattgatgtt tcttaccttt 60
ccactcctgg ttctttattt ttactggtag aactatctgc agacacctca aacttgtcag 120
<210>577
<211>124
<212>DNA
<213> Artificial sequence
<400>577
ttcagcatga ttttgaagtc agaggagatg tggtcaatgg aagaaaccac caaggtccaa 60
agcgagcaag agaatcccag gacagaaagg taaagctccc tccctcaagt tgacaaaaat 120
ctca 124
<210>578
<211>120
<212>DNA
<213> Artificial sequence
<400>578
ttcagccacc aaggagttgt ggcaccaaat acgaaacacc cataaagaaa aaagaactga 60
attctcctca gatgactcca tttaaaaaat tcaatgaaat ttctcttttg gaaagtaatt 120
<210>579
<211>111
<212>DNA
<213> Artificial sequence
<400>579
ttcaggtcta aatggagccc agatggagaa aataccccta ttgcatattt cttcatgtga 60
ccaaaatatt tcagaaaaag acctattaga cacagagaac aaaagaaaga a 111
<210>580
<211>110
<212>DNA
<213> Artificial sequence
<400>580
ttcagtcctt ctactgtcct ggctactaaa tattttatgt acatcagcct gaaaaggact 60
tctggctatg caagggtccc ttaaagattt tctgcttgaa gtctcccttg 110
<210>581
<211>106
<212>DNA
<213> Artificial sequence
<400>581
ttcattctgc agatgctgag tttgtgtgtg aacggacact gaaatatttt ctaggaattg 60
cgggaggaaa atgggtagtt agctatttct gtaagtataa tactat 106
<210>582
<211>113
<212>DNA
<213> Artificial sequence
<400>582
ttcatttcag ggtatcaaaa agtctatatt cagaataaga gaatcaccta aagagacttt 60
caatgcaagt ttttcaggtc atatgactga tccaaacttt aaaaaagaaa ctg 113
<210>583
<211>120
<212>DNA
<213> Artificial sequence
<400>583
ttccaaagaa tgcaaattta taatccagag tatatacatt ctcactgaat tattgtactg 60
tttcaggaag gaatgttccc aatagtagac ataaaagtct tcgcacagtg aaaactaaaa 120
<210>584
<211>120
<212>DNA
<213> Artificial sequence
<400>584
ttcctgaccc tagacctttt cctctgccct tatcatcgct tttcagtgat ggaggaaatg 60
ttggttgtgt tgatgtaatt attcaaagag cataccctat acaggtatga tgtattcttg 120
<210>585
<211>117
<212>DNA
<213> Artificial sequence
<400>585
ttctacagag tgaacccgaa aatccttcct tggtaaaacc atttgttttc ttcttcttct 60
tcttcttctt ttcttttttt tttctttttt ttttttgaga tggagtcttg ctctgtg 117
<210>586
<211>116
<212>DNA
<213> Artificial sequence
<400>586
ttctcattcc atttaaagca gtattaactt cacagaaaag tagtgaatac cctataagcc 60
agaatccaga aggcctttct gctgacaagt ttgaggtgtc tgcagatagt tctacc 116
<210>587
<211>120
<212>DNA
<213> Artificial sequence
<400>587
ttctccaaac agttatactg agtatttggc gtccatcatc agatttatat tctctgttaa 60
cagaaggaaa gagatacaga atttatcatc ttgcaacttc aaaatctaaa agtaaatctg 120
<210>588
<211>120
<212>DNA
<213> Artificial sequence
<400>588
ttctgctgtg cctgactggc atttggttgt actttttttt ctttatctct tcactgctag 60
aacaactatc aatttgcaat tcagtacaat taggtgggct tagatttcta ctgactacta 120
<210>589
<211>120
<212>DNA
<213> Artificial sequence
<400>589
ttctggggtc aggccagaca ccaccatgga cattcttttg ttgacccttt ctgttgaagc 60
tgtcaattct ggcttctccc tgctcacact ttcttccatt gcattatacc cagcagtatc 120
<210>590
<211>120
<212>DNA
<213> Artificial sequence
<400>590
ttcttgcagt aaagcaggca atatctggaa cttctccagt ggcttcttca tttcagggta 60
tcaaaaagtc tatattcaga ataagagaat cacctaaaga gactttcaat gcaagttttt 120
<210>591
<211>120
<212>DNA
<213> Artificial sequence
<400>591
ttgaaacctt gaatgtattc tgcaaatact gagcatcaag ttcactttct tccatttcta 60
tgcttgtttc ccgactgtgg ttaacttcat gtcccaatgg atacttaaag ccttctgtgt 120
<210>592
<211>114
<212>DNA
<213> Artificial sequence
<400>592
ttgaatgctc tttccttcct ggggatccag ggtgtccacc caattgtggt tgtgcagcca 60
gatgcctgga cagaggacaa tggcttccat ggtaaggtgc ctgcatgtac ctgt 114
<210>593
<211>120
<212>DNA
<213> Artificial sequence
<400>593
ttgagaaaca cactcagcaa gtgattatca accttttaag gacactaaaa taagaaaaga 60
catgtaaaca aataaaaata agatgcagca acagtagaaa acctctataa tcaatacatc 120
<210>594
<211>120
<212>DNA
<213> Artificial sequence
<400>594
ttgagacttc tgatacattt tttcagactg caagtgggaa aaatattagt gtcgccaaag 60
agtcatttaa taaaattgta aatttctttg atcagaaacc agaagaattg cataactttt 120
<210>595
<211>117
<212>DNA
<213> Artificial sequence
<400>595
ttgagatcac agctgcccca aagtgtaaag aaatgcagaa ttctctcaat aatgataaaa 60
accttgtttc tattgagact gtggtgccac ctaagctctt aagtgataat ttatgta 117
<210>596
<211>123
<212>DNA
<213> Artificial sequence
<400>596
ttgcagaatg tgaaaagcta tttttccaat catgatgaaa gtctgaagaa aaatgataga 60
tttatcgctt ctgtgacaga cagtgaaaac acaaatcaaa gagaagctgc aagtcatggt 120
aag 123
<210>597
<211>120
<212>DNA
<213> Artificial sequence
<400>597
ttgctgacat tcagagtgaa gaaattttac aacataacca aaatatgtct ggattggaga 60
aagtttctaa aatatcacct tgtgatgtta gtttggaaac ttcagatata tgtaaatgta 120
<210>598
<211>120
<212>DNA
<213> Artificial sequence
<400>598
ttgctggaga cagagaacac aagcagagat tagtgtcaat tcattctcct ggactaggct 60
ctaatcaatc gactccaggg tcctggttgt atgagttctt aggattaatg aggtagaagc 120
<210>599
<211>120
<212>DNA
<213> Artificial sequence
<400>599
ttgctttagg aaatactaag gaacttcatg aaacagactt gacttgtgta aacgaaccca 60
ttttcaagaa ctctaccatg gttttatatg gagacacagg tgataaacaa gcaacccaag 120
<210>600
<211>120
<212>DNA
<213> Artificial sequence
<400>600
ttgcttttat tattagcata taccaaaata aataggcata ttagagtttc ctttcttgca 60
tcttaaaatt catctaacac atctataata acattctttt cttttttttc cattctagga 120
<210>601
<211>117
<212>DNA
<213> Artificial sequence
<400>601
ttggaggaaa acagacaaaa gcaaaacatt gatggacatg gctctgatga tagtaaaaat 60
aagattaatg acaatgagat tcatcagttt aacaaaaaca actccaatca agcagta 117
<210>602
<211>120
<212>DNA
<213> Artificial sequence
<400>602
ttggcttgtt actcttcttg gctccagttg caggttcttt accttccatg agttgtaggt 60
ttctgctgtg cctgactggc atttggttgt actttttttt ctttatctct tcactgctag 120
<210>603
<211>119
<212>DNA
<213> Artificial sequence
<400>603
ttggttgtgt tgatgtaatt attcaaagag cataccctat acaggtatga tgtattcttg 60
aaacttacca tatatttctt tcttttgata caattaattt gtttgtttgt ttgagatgg 119
<210>604
<211>120
<212>DNA
<213> Artificial sequence
<400>604
ttgtccagat ttctgctaac agtactcggc ctgctcgctg gtataccaaa cttggattct 60
ttcctgaccc tagacctttt cctctgccct tatcatcgct tttcagtgat ggaggaaatg 120
<210>605
<211>96
<212>DNA
<213> Artificial sequence
<400>605
ttgttatgaa aacaggtata ccaagaacct ttacagaata ccttgcatct gctgcataaa 60
accacatgag gcgaggcacg gtggcgcatg cctgta 96
<210>606
<211>121
<212>DNA
<213> Artificial sequence
<400>606
ttgtttccta ggcacaataa aagatcgaag attgtttatg catcatgttt ctttagagcc 60
gattacctgt gtaccctttc ggtaagacat gtttaaattt ttctaaattc taatacagta 120
t 121
<210>607
<211>120
<212>DNA
<213> Artificial sequence
<400>607
tttaaacagt ggaattctag agtcacactt cctaaaatat gcatttttgt tttcactttt 60
agatatgata cggaaattga tagaagcaga agatcggcta taaaaaagat aatggaaagg 120
<210>608
<211>120
<212>DNA
<213> Artificial sequence
<400>608
tttaaagcat tacattacgt aatcatatac ggcagtatgg ttaaggtttc tgtgtagtct 60
gtgacttcca tgtcaaaatg ttgcacaagc cagttgtcag tgacagttgc catcccacac 120
<210>609
<211>120
<212>DNA
<213> Artificial sequence
<400>609
tttaacacat tagaaaaaca tatatatata tctttttaaa aggtttataa aatgacaact 60
tcattttatc attttaaaat aaagtaaatt taagatttgg aaggttttag aataatacaa 120
<210>610
<211>120
<212>DNA
<213> Artificial sequence
<400>610
tttaattctc agtatttctt agataaattc agtttttatt ctcagttatt cagtgacttg 60
tttaaacagt ggaattctag agtcacactt cctaaaatat gcatttttgt tttcactttt 120
<210>611
<211>120
<212>DNA
<213> Artificial sequence
<400>611
tttagatgtt caggagagtt attttccttt tttgcaaaat tatagctgtt tgcatctgta 60
aaatacaagg gaaaacatta tgtttgcagt tagagaaaaa tgtatgaatt ataatcaaag 120
<210>612
<211>120
<212>DNA
<213> Artificial sequence
<400>612
tttaggagaa ccctcaatca aaagaaactt attaaatgaa tttgacagga taatagaaaa 60
tcaagaaaaa tccttaaagg cttcaaaaag cactccagat ggtaaaatta gctttttatt 120
<210>613
<211>120
<212>DNA
<213> Artificial sequence
<400>613
tttagtagcc aggacagtag aaggactgaa gagtgagagg agctcccagg gcctggaaag 60
gccactttgt aagctcattc ttggggtcct gtggctctgt acctgtggct ggctgcagtc 120
<210>614
<211>120
<212>DNA
<213> Artificial sequence
<400>614
tttataaatt tttctgatga atggttttat aggaacgcta tgttattaaa taatttctac 60
tttttcctac tgtggttgct tccaacctag catcattacc aaattatata ccttttggtt 120
<210>615
<211>115
<212>DNA
<213> Artificial sequence
<400>615
tttatatgga gacacaggtg ataaacaagc aacccaagtg tcaattaaaa aagatttggt 60
ttatgttctt gcagaggaga acaaaaatag tgtaaagcag catataaaaa tgact 115
<210>616
<211>121
<212>DNA
<213> Artificial sequence
<400>616
tttcaaagcg ccagtcattt gctccgtttt caaatccagg aaatgcagaa gaggaatgtg 60
caacattctc tgcccactct gggtccttaa agaaacaaag tccaaaagtc acttttgaat 120
g 121
<210>617
<211>120
<212>DNA
<213> Artificial sequence
<400>617
tttcaggaag gaatgttccc aatagtagac ataaaagtct tcgcacagtg aaaactaaaa 60
tggatcaagc agatgatgtt tcctgtccac ttctaaattc ttgtcttagt gaaaggtatg 120
<210>618
<211>120
<212>DNA
<213> Artificial sequence
<400>618
tttcggtaag acatgtttaa atttttctaa attctaatac agtatgagaa aagtctcgtt 60
tttataaatg aacatttcta aaaataatga cactaacgtt aagaagttaa cacttcccgt 120
<210>619
<211>127
<212>DNA
<213> Artificial sequence
<400>619
tttctttata atttatagat tttgcatgct gaaacttctc aaccagaaga aagggccttc 60
acagtgtcct ttatgtaaga atgatataac caaaaggtat ataatttggt aatgatgcta 120
ggttgga 127
<210>620
<211>110
<212>DNA
<213> Artificial sequence
<400>620
tttgctttgt tttattttag tcctgttgtt ctacaatgta cacatgtaac accacaaaga 60
gataagtcag gtatgattaa aaacaatgct ttttattctt agaatactag 110
<210>621
<211>110
<212>DNA
<213> Artificial sequence
<400>621
tttgggaaaa cctatcggaa gaaggcaagc ctccccaact taagccatgt aactgaaaat 60
ctaattatag gagcatttgt tactgagcca cagataatac aagagcgtcc 110
<210>622
<211>120
<212>DNA
<213> Artificial sequence
<400>622
tttggtaact cagactcagc atcagcaaaa accttaggtg ttaaacgtta ggtgtaaaaa 60
tgcaattctg aggtgttaaa gggaggaggg gagaaatagt attatactta cagaaatagc 120
<210>623
<211>117
<212>DNA
<213> Artificial sequence
<400>623
tttgtcaaat tcaagaattg gaaaaagaag aggagagccc cttatcttag tgggtaagtg 60
ttcattttta cctttcgtgt tgccaatcac tatttttaaa gtgtttattc agtagac 117
<210>624
<211>116
<212>DNA
<213> Artificial sequence
<400>624
ttttagccat caatgggcaa agaccctaaa gtacagagag gcctgtaaag accttgaatt 60
agcatgtgag accattgaga tcacagctgc cccaaagtgt aaagaaatgc agaatt 116
<210>625
<211>120
<212>DNA
<213> Artificial sequence
<400>625
ttttcaagaa ctctaccatg gttttatatg gagacacagg tgataaacaa gcaacccaag 60
tgtcaattaa aaaagatttg gtttatgttc ttgcagagga gaacaaaaat agtgtaaagc 120
<210>626
<211>115
<212>DNA
<213> Artificial sequence
<400>626
ttttcaggtc atatgactga tccaaacttt aaaaaagaaa ctgaagcctc tgaaagtgga 60
ctggaaatac atactgtttg ctcacagaag gaggactcct tatgtccaaa tttaa 115
<210>627
<211>117
<212>DNA
<213> Artificial sequence
<400>627
ttttcatata atgtggtaaa ttcatctgct ttctctggat ttagtacagc aagtggaaag 60
caagtttcca ttttagaaag ttccttacac aaagttaagg gagtgttaga ggaattt 117
<210>628
<211>118
<212>DNA
<213> Artificial sequence
<400>628
ttttctcccc attgcagcac aactaaggaa cgtcaagaga tacagaatcc aaattttacc 60
gcacctggtc aagaatttct gtctaaatct catttgtatg aacatctgac tttggaaa 118
<210>629
<211>108
<212>DNA
<213> Artificial sequence
<400>629
tttttacccc cagtggtatg tgggagtttg tttcatacac caaagtttgt gaaggtaaat 60
attctacctg gtttattttt atgacttagt aattgagaat ttgacaat 108
<210>630
<211>120
<212>DNA
<213> Artificial sequence
<400>630
tttttcctac tgtggttgct tccaacctag catcattacc aaattatata ccttttggtt 60
atatcattct tacataaagg acactgtgaa ggccctttct tctggttgag aagtttcagc 120
<210>631
<211>120
<212>DNA
<213> Artificial sequence
<400>631
tttttttttt gtaaatagta catatagttt tatagatgac gattccttct gtgttttttt 60
ctgcttttta aaatcttcat atcttatatt taatcttagg catcatctgt atacatgatt 120
Claims (4)
1. The human BRCA1/2 gene variation detection kit comprises a human BRCA1/2 gene variation detection quality control product and a capture probe;
wherein the capture probe is a mixture of 631 probes shown in SEQ ID NO 1-631 which are mixed together according to the same mass;
wherein the quality control product is prepared by the following method:
(1) selecting a human tumor cell line with positive BRCA1/2 gene variation and stable passage for culturing, respectively extracting and purifying each cell genome DNA, and respectively diluting the purified DNA to the same concentration to obtain quality control product raw material DNA;
(2) determining potential variation sites on BRCA1/2 gene in each cell line by Sanger sequencing method, and using heterozygous and homozygous variation sites confirmed by Sanger sequencing method as positive control sites;
(3) mixing the DNA of quality control material from different cell lines according to a certain proportion to obtain the quality control material.
2. The kit according to claim 1, wherein the selected stably passable human tumor cell lines are HCC1599, HCT-15, Jurkat and NCI-H720 cell lines.
3. The kit according to claim 2, wherein the quality control material DNA obtained from HCC1599, HCT-15, Jurkat and NCI-H720 cell lines in step (3) is purified according to a ratio of 1:1: 1:1 volume ratio was mixed homogeneously.
4. The kit according to any one of claims 1-3, further comprising a mixture of end-repair enzymes, an end-repair reaction buffer, a DNA ligase, a ligation buffer, a linker comprising a molecular tag, a library amplification primer, a PCR pre-mix, a linker blocker, a DNA blocker, a hybridization buffer, a hybridization enhancer, a magnetic bead wash, a hybridization wash, a capture library PCR primer, a nucleic acid purification magnetic bead, and a streptavidin magnetic bead.
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| CN109097443B (en) * | 2017-06-21 | 2022-03-22 | 苏州吉赛基因测序科技有限公司 | Method for capturing genome target sequence for high-throughput sequencing |
| CN107338292A (en) * | 2017-07-10 | 2017-11-10 | 上海思路迪生物医学科技有限公司 | Method and kit based on high-flux sequence detection human genome mutational load |
| CN108085387B (en) * | 2017-11-27 | 2020-03-27 | 天津诺禾致源生物信息科技有限公司 | Specific capture probe, kit and sequencing library for detecting human BRCA1/2 gene mutation and construction method thereof |
| CN109402257B (en) * | 2018-11-03 | 2023-06-23 | 杭州链康医学检验实验室有限公司 | Primer, method and kit for detecting mutation sites of human BRCA1and BRCA2 gene full-coding sequences |
| WO2020103862A1 (en) * | 2018-11-21 | 2020-05-28 | 广州易锦生物技术有限公司 | Dna reference standard and use thereof |
| CN109628558B (en) * | 2018-12-21 | 2020-01-14 | 北京优迅医学检验实验室有限公司 | Capture probe for detecting gene mutation through high-throughput sequencing and application thereof |
| CN109628568A (en) * | 2019-01-10 | 2019-04-16 | 上海境象生物科技有限公司 | A kind of internal standard and its application polluted for differentiating and calibrating high-flux sequence |
| CN110129439A (en) * | 2019-04-28 | 2019-08-16 | 安徽鼎晶生物科技有限公司 | A kind of people BRCA1/2 genetic mutation detection quality-control product and its preparation method and application |
| CN110444255B (en) * | 2019-08-30 | 2023-06-13 | 深圳裕策生物科技有限公司 | Biological information quality control method and device based on second-generation sequencing and storage medium |
| CN113005188A (en) * | 2020-12-29 | 2021-06-22 | 阅尔基因技术（苏州）有限公司 | Method for evaluating base damage, mismatching and variation in sample DNA by one-generation sequencing |
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