CN112741690B - Simulation method, device, computer equipment and storage medium for release of blood vessel stent - Google Patents

Simulation method, device, computer equipment and storage medium for release of blood vessel stent Download PDF

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CN112741690B
CN112741690B CN202011625547.2A CN202011625547A CN112741690B CN 112741690 B CN112741690 B CN 112741690B CN 202011625547 A CN202011625547 A CN 202011625547A CN 112741690 B CN112741690 B CN 112741690B
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stent
blood vessel
vascular
compressor
shell
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CN112741690A (en
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冷晓畅
万曙
金肜伯
陈林辉
王明
向建平
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Arteryflow Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • A61B17/12118Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm for positioning in conjunction with a stent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • A61B17/12145Coils or wires having a pre-set deployed three-dimensional shape
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    • A61B34/25User interfaces for surgical systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/101Computer-aided simulation of surgical operations
    • A61B2034/102Modelling of surgical devices, implants or prosthesis
    • A61B2034/104Modelling the effect of the tool, e.g. the effect of an implanted prosthesis or for predicting the effect of ablation or burring
    • AHUMAN NECESSITIES
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    • A61B2034/105Modelling of the patient, e.g. for ligaments or bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/107Visualisation of planned trajectories or target regions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/108Computer aided selection or customisation of medical implants or cutting guides

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Abstract

The present application relates to a simulation method, apparatus, computer device and storage medium for stent release. The method comprises the following steps: compressing the vascular stent by using a compressor to enable the vascular stent to be in a compressed state, wherein the vascular stent and the compressor are all three-dimensional models which are constructed in advance and used for simulation calculation; embedding the blood vessel stent into a shell under a compressed state to form a whole and using the blood vessel stent as a stent conveying system, wherein the shell is cylindrical; moving the stent delivery system to the far end along the axis of the guide piece until the preset position is reached, wherein the axis of the guide piece is superposed with the central line of the tumor-carrying blood vessel; and releasing the restraint on the blood vessel stent, and further expanding the blood vessel stent to be attached to the tumor-carrying blood vessel. By adopting the method, the simulation speed can be improved, and the practicability and the accuracy are considered.

Description

Simulation method, device, computer equipment and storage medium for release of blood vessel stent
Technical Field
The present application relates to the field of transformed medicine, and in particular to a simulation method, apparatus, computer device and storage medium for release of a vessel stent.
Background
Intracranial aneurysms are pathological bulges of the intracranial arterial wall, which are common in arterial bifurcations of the cerebrovascular willis ring. Aneurysms affect approximately 5% of all humans. The consequences of aneurysm rupture are fatal, with about 50% being non-viable, and varying degrees of physical dysfunction remaining.
Coil embolization is currently the most important method of treating aneurysms. The treatment procedure involves releasing a series of coils into the lumen of the aneurysm to reduce intratumoral blood flow by embolizing the aneurysm. The coil filling causes thrombosis in the subsequent aneurysm, eventually embolizing the aneurysm to isolate the aneurysm from blood circulation. For wide-necked aneurysms, a mesh-phobic stent is often placed in the parent vessel to prevent the coil from falling out of the aneurysm cavity into the parent vessel, a procedure called stent-assisted coil embolization. In the prior art, a dense mesh stent is used for remodeling a parent artery to embolize a cerebral aneurysm, and the principle is that the dense mesh stent with the coverage rate of a metal mesh of about 30-35% is placed to reduce the blood flow speed and the blood flow volume entering an aneurysm cavity, so that thrombus is formed in the aneurysm cavity. The dense mesh stent is particularly effective for large aneurysms, wide-neck aneurysms and other complex aneurysms, and sometimes a small number of spring rings can be placed at the same time when the dense mesh stent is implanted.
Prospective randomized multi-center clinical trials have shown that coil and stent interventional procedures have better outcomes for ruptured and unbroken aneurysms than traditional craniotomy procedures (clamping of the aneurysm by an aneurysm clip). However, one of the biggest weaknesses of coil embolization is the high rate of recurrence, up to 30%, and the need for retreatment of these recurrent aneurysms. The mechanism of recurrence of coil embolization is not fully understood at present, but from intuitive and extensive academic studies, it has been shown that recurrence following coil or stent-assisted coil embolization is closely related to changes in hemodynamics.
Computational Fluid Dynamics (CFD) based on medical images is widely used in hemodynamic analysis before and after aneurysm treatment. However, computational fluid dynamics simulation requires accurate coil, stent or dense mesh stent geometry after intravascular release. This problem is the challenge of current virtual release simulation calculations for coils and stents because previous methods do not allow for rapid and accurate acquisition of the three-dimensional structure of coils and stents after their actual release.
At present, the simulation method of intracranial aneurysm has a porous medium-based method and a quick release method. For example, publication No. CN103198202A describes a method for releasing a stent-graft from an aneurysm based on a mathematical model expansion method. Although these methods are relatively fast, their accuracy is not satisfactory for subsequent hemodynamic analysis. The application of traditional finite element algorithms in virtual treatment of aneurysm stents and coils is described in the patent literature of international patent application (PTC/US 2015/012941). The traditional method based on finite element is accurate, the simulation process is carried out according to the real process of stent clamping, conveying and releasing, the method can accurately calculate the mechanical and mechanical characteristics of the stent in the releasing process, however, the calculation time is very long, and therefore, the method is limited in practical clinical application. For example, the HiFiVS calculation based on the finite element method takes more than 100 hours in the process of calculating the delivery of the dense mesh stent, is time-consuming, uneconomical and difficult to meet the requirement of timeliness in clinic.
Disclosure of Invention
In view of the above, there is a need to provide a simulation method, apparatus, computer device and storage medium for vessel stent release, which can improve the calculation speed while ensuring accuracy.
A simulation method for release of a stent for a blood vessel, comprising:
compressing a vascular stent by using a compressor to enable the vascular stent to be in a compressed state, wherein the vascular stent and the compressor are pre-constructed three-dimensional models used for simulation calculation;
embedding the vascular stent in a compressed state into a shell to form a whole and using the vascular stent as a stent delivery system, wherein the shell is cylindrical;
moving the stent delivery system to the far end along the axis of a guide part until the stent delivery system reaches a preset position, wherein the axis of the guide part is superposed with the central line of the tumor-carrying blood vessel;
and releasing the restraint on the blood vessel stent, so that the blood vessel stent is further expanded to be attached to the tumor-carrying blood vessel.
Optionally, before compressing the vessel stent with the compressor, the method comprises: sleeving the compressor in an unstressed state on the periphery of the intravascular stent, wherein a gap is reserved between the inner peripheral wall of the compressor and the outer peripheral wall of the intravascular stent, and the gap is 1-2 times of the wall thickness of the intravascular stent.
Optionally, the outer diameter of the shell is larger than the outer diameter of the compressed blood vessel stent, and the inner diameter of the shell is smaller than the inner diameter of the compressed blood vessel stent.
Optionally, the stent delivery system is moved distally along the guide member axis, the stent and housing remaining relatively stationary.
Optionally, constructing the guide comprises: a centerline of the parent vessel is obtained, swept along the centerline to create a guide with a circular cross-section.
Optionally, the diameter of the cross section of the guide member is smaller than the inner diameter of the compressed vascular stent.
Optionally, the guide member includes a proximal-to-distal extension within the parent vessel in the lengthwise direction, and a linear extension from the proximal end back to the distal end.
The present application also provides a simulation device for release of a vascular stent, comprising:
the blood vessel stent compression module is used for compressing the blood vessel stent by using a compressor so that the blood vessel stent is in a compressed state, and the blood vessel stent and the compressor are pre-constructed three-dimensional models used for simulation calculation;
the stent delivery system forming module is used for embedding the vascular stent into a shell in a compressed state to form a whole and is used as a stent delivery system, wherein the shell is cylindrical;
the stent conveying system moving module is used for moving the stent conveying system to the far end along the axis of the guide piece until the preset position is reached, and the axis of the guide piece is superposed with the central line of the tumor-carrying blood vessel;
and the blood vessel stent releasing module is used for releasing the restraint on the blood vessel stent and further expanding the blood vessel stent to be jointed with the tumor-carrying blood vessel.
The present application further provides a computer device, comprising a memory and a processor, wherein the memory stores a computer program, and the processor implements the following steps when executing the computer program:
compressing a vascular stent by using a compressor to enable the vascular stent to be in a compressed state, wherein the vascular stent and the compressor are pre-constructed three-dimensional models used for simulation calculation;
embedding the vascular stent in a compressed state into a shell to form a whole and using the vascular stent as a stent delivery system, wherein the shell is cylindrical;
moving the stent delivery system to the far end along the axis of a guide part until the stent delivery system reaches a preset position, wherein the axis of the guide part is superposed with the central line of the tumor-carrying blood vessel;
and releasing the restraint on the blood vessel stent, so that the blood vessel stent is further expanded to be attached to the tumor-carrying blood vessel.
A computer-readable storage medium, on which a computer program is stored which, when executed by a processor, carries out the steps of:
compressing a vascular stent by using a compressor to enable the vascular stent to be in a compressed state, wherein the vascular stent and the compressor are pre-constructed three-dimensional models used for simulation calculation;
embedding the vascular stent in a compressed state into a shell to form a whole and using the vascular stent as a stent delivery system, wherein the shell is cylindrical;
moving the stent delivery system to the far end along the axis of a guide part until the stent delivery system reaches a preset position, wherein the axis of the guide part is superposed with the central line of the tumor-carrying blood vessel;
and releasing the restraint on the blood vessel stent, so that the blood vessel stent is further expanded to be attached to the tumor-carrying blood vessel.
The simulation method, the simulation device, the computer equipment and the storage medium for releasing the blood vessel stent can obtain the selection of the optimal aneurysm treatment scheme through further calculation and the output of relevant indexes so as to carry out precise medical treatment. And the rapid virtual implantation method of the stent of the traditional finite element method is optimized, the accuracy of the simulation structure is ensured, meanwhile, the three-dimensional model after the stent is released can be rapidly obtained, and a balance is achieved between the accuracy and the effectiveness.
Drawings
FIG. 1 is a schematic flow diagram of a simulation method for stent release in one embodiment;
FIG. 2 is a schematic diagram showing two views of a vascular stent in a compressor according to an embodiment;
FIG. 3 is a schematic diagram of two views of a deployment guide of the stent delivery system in accordance with one embodiment;
FIG. 4 is a schematic illustration of the movement of a stent delivery system in a parent vessel in one embodiment;
FIG. 5 is a schematic illustration of a stent delivery system in a compressed state and in a released state in a parent vessel in one embodiment;
FIG. 6 is a block diagram of a simulation apparatus for stent release in one embodiment;
FIG. 7 is a diagram illustrating an internal structure of a computer device according to an embodiment.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
As shown in fig. 1-7, in one embodiment of the present application, there is provided a simulation method for stent release, comprising:
s100, compressing a vascular stent by using a compressor to enable the vascular stent to be in a compressed state, wherein the vascular stent and the compressor are pre-constructed three-dimensional models used for simulation calculation;
step S120, embedding the vascular stent into a shell in a compressed state to form a whole and using the vascular stent as a stent conveying system, wherein the shell is cylindrical;
step S140, moving the stent conveying system to the far end along the axis of a guide part until the stent conveying system reaches a preset position, wherein the axis of the guide part is superposed with the central line of the tumor-carrying blood vessel;
and step S160, releasing the restraint on the blood vessel stent, and further expanding the blood vessel stent to be attached to the tumor-carrying blood vessel.
Since the present application relates to simulation calculation and display, components such as the vascular stent and an in vivo environment are three-dimensional models without special statement, and of course, in the following embodiments, a computer environment on which the simulation release method of the present application operates is mentioned, and a processor or a memory and the like are all physical hardware.
Before the simulation calculation is carried out, the three-dimensional model of the designed mechanical or human body structure can be constructed in advance, the interventional device is mainly applied to a blood vessel stent, and the current stent for treating intracranial aneurysm is mainly a self-expanding stent which is divided into a laser carving stent and a weaving type stent. The simulation method referred to in this application is mainly applied to Solitaire stents (Medtronic corporation, usa), which belong to laser engraved stents. The three-dimensional model can be constructed by software for this type of stent.
The tumor-bearing blood vessel is an interesting intercepting segment, and the length of the tumor-bearing blood vessel, namely the length involved in the simulation calculation, is about the same as the length of the blood vessel stent after the blood vessel stent is completely released.
In step S100, the blood vessel stent is compressed by a compressor, and the compressor may be directly retained after the compression, or the compressor may be removed and the boundary condition of the blood vessel stent is maintained, so that the blood vessel stent maintains the compressed state.
Before the vascular stent is compressed by the compressor, the compressor in an unstressed state is sleeved on the periphery of the vascular stent. In order to prevent causing the unconvergence of the calculation in the subsequent finite element analysis calculation, the inner peripheral wall of the compressor and the outer peripheral wall of the blood vessel stent are separated by a gap which is 1-2 times of the wall thickness of the blood vessel stent, as shown in fig. 2, wherein (a) is a schematic cross-sectional view of the blood vessel stent in an unstressed state in the compressor, and (b) is a schematic longitudinal view of the blood vessel stent in the unstressed state in the compressor.
When the compressor compresses the blood vessel support, the compressor is utilized to gradually and radially fold the blood vessel support, namely, displacement boundary conditions are applied to the outer wall of the blood vessel support until the inner diameter of the blood vessel support reaches a preset value. The device can be generally divided into two parts in the process, namely, the compressor is slowly subjected to displacement loading, and the compressor is firstly contacted with the surface of the peripheral wall of the blood vessel stent; and then the displacement loading speed is increased, and the vascular stent is compressed.
In the embodiment, the contact assembly of the simulated blood vessel stent and the catheter in the stent conveying process in the traditional finite element method is eliminated, and the compressed blood vessel stent is fixed in a shell with a certain thickness to quickly convey the blood vessel stent.
Because the catheter is an indispensable intervention device for transporting the vascular stent in actual operation, the catheter can be constructed in three dimensions in a delivery model to simulate the real situation, but the catheter has different models, so that a large amount of calculation is needed during the three-dimensional construction, and therefore in the application, the calculation resources are greatly saved in the mode that the compressed vascular stent directly generates a corresponding shell. In addition, the wall of the catheter is thin, and when the vascular stent is conveyed, the tumor-carrying blood vessel with a complex path can cause the vascular stent to be difficult to keep the original state, so that the simulation process speed is slow.
In step S120, in order to prevent kinks in the course of the stent delivery in the tortuous tumor-bearing vessel, a cylindrical shell with a thickness is created by software and the entire stent is wrapped and integrated.
In order to make the blood vessel support be completely embedded in the shell body, the outer diameter of the shell body is greater than the outer diameter of the compressed blood vessel support, and the inner diameter of the shell body is less than the inner diameter of the compressed blood vessel support. And the length of the shell is greater than that of the blood vessel stent. The gaps between the outer peripheral wall of the blood vessel stent and the outer peripheral wall of the shell and between the inner peripheral wall of the blood vessel stent and the inner peripheral wall of the shell are generally multiples of the wall thickness of the blood vessel stent.
And after the compressed vascular stent is embedded into the shell, the vascular stent and the shell are bound together through finite element calculation software to form a stent delivery system. And, the stent and the housing remain relatively stationary as the subsequent stent delivery system is moved distally along the axis of the guide.
In this embodiment, the method of freely pushing the stent delivery system in the tumor-bearing vessel from the proximal end to the distal end during the stent delivery process of the conventional finite element simulation vessel is further improved, and the delivery guidance is performed by using the guide part consistent with the extension of the tumor-bearing vessel, so that the delivery speed is increased.
In step S140, when the guide is generated, the center line of the tumor-laden blood vessel is obtained by software, and the guide having a circular cross section is generated by sweeping along the center line, so that the extending path of the guide coincides with the tumor-laden blood vessel.
In this embodiment, the diameter of the cross section of the guiding element is smaller than the inner diameter of the compressed vascular stent, and when moving the stent delivery system, the axis of the stent delivery system can be rapidly moved along the axis of the guiding element to the far end, so as to avoid a great deal of calculation and analysis when the stent delivery system is freely advanced in a circuitous tumor-bearing blood vessel, as shown in fig. 3, wherein (a) is a longitudinal schematic view of the stent delivery system loaded on the guiding element, wherein (b) is a cross-sectional schematic view of the stent delivery system loaded on the guiding element, 1 indicates the guiding element, 2 indicates the compressed vascular stent, and 3 indicates the shell covering the vascular stent.
Because the stent delivery system has a straight axis during delivery, in order to facilitate the stent delivery system to enter the parent vessel, the guide member includes a portion extending from the proximal end to the distal end in the parent vessel and a portion extending straight from the proximal end back to the distal end. Thus, when delivering the stent delivery system, the system can be pre-assembled to the linear extension of the guide member and advanced along the guide member toward the distal end of the parent vessel to complete delivery of the stent, as shown in fig. 5, where (a) is the linear extension of the stent delivery system on the guide member and (b) is the extension of the stent delivery system on the guide member.
The proximal end of the housing exerts a displacement boundary condition parallel to the axial direction along the axial direction of the guide member during the stent delivery, and the stent delivery system is slowly moved forward along the guide member until the distal end of the stent reaches a predetermined position, as shown in fig. 5 (a), at which time the stent is still in a compressed state. During stent delivery, the guide path is simplified to a rigid body and fixed.
After the completion of the delivery, the parent artery is simplified into a rigid body and fixed, and pressure is applied to the inner wall of the stent to gradually expand the stent until the stent is completely attached to the wall, as shown in fig. 5 (b).
When the radial gap between the vascular stent and the tumor-carrying blood vessel is small, the vascular stent is further expanded until the vascular stent is completely attached to the inner wall of the tumor-carrying blood vessel, and if the local gap is large, the vascular stent may not be completely attached to the inner wall of the tumor-carrying blood vessel at the part, so that the attachment rate of the vascular stent and the inner wall of the tumor-carrying blood vessel and the coverage rate of the vascular stent on the inner wall of the tumor-carrying blood vessel are necessary to be calculated for effect evaluation.
It should be understood that, although the steps in the flowchart of fig. 1 are shown in order as indicated by the arrows, the steps are not necessarily performed in order as indicated by the arrows. The steps are not performed in the exact order shown and described, and may be performed in other orders, unless explicitly stated otherwise. Moreover, at least a portion of the steps in fig. 1 may include multiple sub-steps or multiple stages that are not necessarily performed at the same time, but may be performed at different times, and the order of performance of the sub-steps or stages is not necessarily sequential, but may be performed in turn or alternately with other steps or at least a portion of the sub-steps or stages of other steps.
In the simulation method for releasing the blood vessel stent, through improving the traditional finite element method, a shell with a certain thickness is used for replacing a catheter, and a cylindrical guide part is directly generated along the central line of the parent artery, so that the blood vessel stent delivery device is pushed to the far end of the parent artery along the guide part, and a large amount of calculation in the process of freely pushing the stent delivery system is avoided. The improvement of the two aspects greatly accelerates the simulation speed of the stent, greatly shortens the time, obtains a three-dimensional model after the stent is released accurately enough, then obtains the change condition of the hemodynamics through the calculation of CFD, and carries out personalized and precise medical treatment.
In one embodiment, as shown in fig. 6, there is provided a simulation apparatus for stent release, including: a vessel stent compression module 200, a stent delivery system formation module 220, a stent delivery system movement module 240, and a vessel stent release module 260, wherein:
the blood vessel stent compression module 200 is configured to compress a blood vessel stent by using a compressor so that the blood vessel stent is in a compressed state, where the blood vessel stent and the compressor are three-dimensional models which are constructed in advance and used for simulation calculation;
a stent delivery system forming module 220 for embedding the vascular stent in a compressed state into a housing to form a whole and serving as a stent delivery system, wherein the housing is cylindrical;
the stent conveying system moving module 240 is used for moving the stent conveying system to the far end along the axis of the guide piece until the preset position is reached, and the axis of the guide piece is superposed with the central line of the tumor-carrying blood vessel;
and the blood vessel stent releasing module 260 is used for releasing the restraint on the blood vessel stent so as to further expand the blood vessel stent to be jointed with the tumor-carrying blood vessel.
For specific definition of the simulation device for releasing the vessel stent, reference may be made to the above definition of the simulation method for releasing the vessel stent, and details are not repeated here. The modules in the simulation device for releasing the blood vessel stent can be wholly or partially realized by software, hardware and a combination thereof. The modules can be embedded in a hardware form or independent from a processor in the computer device, and can also be stored in a memory in the computer device in a software form, so that the processor can call and execute operations corresponding to the modules.
In one embodiment, a computer device is provided, which may be a terminal, and its internal structure diagram may be as shown in fig. 7. The computer device includes a processor, a memory, a network interface, a display screen, and an input device connected by a system bus. Wherein the processor of the computer device is configured to provide computing and control capabilities. The memory of the computer device comprises a nonvolatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of an operating system and computer programs in the non-volatile storage medium. The network interface of the computer device is used for communicating with an external terminal through a network connection. The computer program is executed by a processor to implement a simulation method for stent release. The display screen of the computer equipment can be a liquid crystal display screen or an electronic ink display screen, and the input device of the computer equipment can be a touch layer covered on the display screen, a key, a track ball or a touch pad arranged on the shell of the computer equipment, an external keyboard, a touch pad or a mouse and the like.
Those skilled in the art will appreciate that the architecture shown in fig. 7 is merely a block diagram of some of the structures associated with the disclosed aspects and is not intended to limit the computing devices to which the disclosed aspects apply, as particular computing devices may include more or less components than those shown, or may combine certain components, or have a different arrangement of components.
In one embodiment, a computer device is provided, comprising a memory and a processor, the memory having a computer program stored therein, the processor implementing the following steps when executing the computer program:
compressing a vascular stent by using a compressor to enable the vascular stent to be in a compressed state, wherein the vascular stent and the compressor are pre-constructed three-dimensional models used for simulation calculation;
embedding the vascular stent in a compressed state into a shell to form a whole and using the vascular stent as a stent delivery system, wherein the shell is cylindrical;
moving the stent delivery system to the far end along the axis of a guide part until the stent delivery system reaches a preset position, wherein the axis of the guide part is superposed with the central line of the tumor-carrying blood vessel;
and releasing the restraint on the blood vessel stent, so that the blood vessel stent is further expanded to be attached to the tumor-carrying blood vessel.
In one embodiment, a computer-readable storage medium is provided, having a computer program stored thereon, which when executed by a processor, performs the steps of:
compressing a vascular stent by using a compressor to enable the vascular stent to be in a compressed state, wherein the vascular stent and the compressor are pre-constructed three-dimensional models used for simulation calculation;
embedding the vascular stent in a compressed state into a shell to form a whole and using the vascular stent as a stent delivery system, wherein the shell is cylindrical;
moving the stent delivery system to the far end along the axis of a guide part until the stent delivery system reaches a preset position, wherein the axis of the guide part is superposed with the central line of the tumor-carrying blood vessel;
and releasing the restraint on the blood vessel stent, so that the blood vessel stent is further expanded to be attached to the tumor-carrying blood vessel.
It will be understood by those skilled in the art that all or part of the processes of the methods of the embodiments described above can be implemented by hardware instructions of a computer program, which can be stored in a non-volatile computer-readable storage medium, and when executed, can include the processes of the embodiments of the methods described above. Any reference to memory, storage, database, or other medium used in the embodiments provided herein may include non-volatile and/or volatile memory, among others. Non-volatile memory can include read-only memory (ROM), Programmable ROM (PROM), Electrically Programmable ROM (EPROM), Electrically Erasable Programmable ROM (EEPROM), or flash memory. Volatile memory can include Random Access Memory (RAM) or external cache memory. By way of illustration and not limitation, RAM is available in a variety of forms such as Static RAM (SRAM), Dynamic RAM (DRAM), Synchronous DRAM (SDRAM), Double Data Rate SDRAM (DDRSDRAM), Enhanced SDRAM (ESDRAM), Synchronous Link DRAM (SLDRAM), Rambus Direct RAM (RDRAM), direct bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM).
The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (9)

1. A simulation method for release of a stent, comprising:
compressing a vascular stent by using a compressor to enable the vascular stent to be in a compressed state, wherein the vascular stent and the compressor are pre-constructed three-dimensional models used for simulation calculation;
embedding the vascular stent into a shell in a compressed state to form a whole and using the vascular stent as a stent conveying system, wherein the shell is cylindrical and wraps the vascular stent;
moving the stent delivery system to the far end along the axis of the guide piece until the preset position is reached, wherein the axis of the guide piece is overlapped with the central line of the tumor-carrying blood vessel, and when the stent delivery system moves to the far end along the axis of the guide piece, the blood vessel stent and the shell are kept relatively fixed;
and releasing the restraint on the blood vessel stent, so that the blood vessel stent is further expanded to be attached to the tumor-carrying blood vessel.
2. The simulation method for stent release according to claim 1, comprising, before compressing the stent with a compressor: sleeving the compressor in an unstressed state on the periphery of the intravascular stent, wherein a gap is reserved between the inner peripheral wall of the compressor and the outer peripheral wall of the intravascular stent, and the gap is 1-2 times of the wall thickness of the intravascular stent.
3. The simulation method for stent release according to claim 1, wherein the shell has an outer diameter larger than an outer diameter of the compressed stent and an inner diameter smaller than an inner diameter of the compressed stent.
4. The simulation method for stent release according to claim 1, wherein constructing the guide comprises: a centerline of the parent vessel is obtained, swept along the centerline to create a guide with a circular cross-section.
5. The simulation method for stent release according to claim 4, wherein the diameter of the cross section of the guide member is smaller than the inner diameter of the compressed stent.
6. The simulation method for stent release according to claim 1, wherein the guide member comprises a portion extending from the proximal end to the distal end within the parent vessel in the lengthwise direction, and a portion linearly extending from the proximal end back to the distal end.
7. A simulation method device for release of a stent, comprising:
the blood vessel stent compression module is used for compressing the blood vessel stent by using a compressor so that the blood vessel stent is in a compressed state, and the blood vessel stent and the compressor are pre-constructed three-dimensional models used for simulation calculation;
the stent delivery system forming module is used for embedding the vascular stent into a shell under a compressed state to form a whole and using the vascular stent as a stent delivery system, wherein the shell is cylindrical and wraps the vascular stent;
the stent conveying system moving module is used for moving the stent conveying system to the far end along the axis of the guide piece until the preset position is reached, the axis of the guide piece is superposed with the central line of the tumor-carrying blood vessel, and when the stent conveying system moves to the far end along the axis of the guide piece, the blood vessel stent and the shell are kept relatively fixed;
and the blood vessel stent releasing module is used for releasing the restraint on the blood vessel stent and further expanding the blood vessel stent to be jointed with the tumor-carrying blood vessel.
8. A computer device comprising a memory and a processor, the memory storing a computer program, characterized in that the processor, when executing the computer program, implements the steps of the simulation method for vessel stent release of any one of claims 1 to 6.
9. A computer-readable storage medium, on which a computer program is stored which, when being executed by a processor, carries out the steps of the simulation method for vessel stent release of any one of claims 1 to 6.
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