CN112716601B - Simulation method and device for rapid release of vascular stent, computer equipment and storage medium - Google Patents

Simulation method and device for rapid release of vascular stent, computer equipment and storage medium Download PDF

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CN112716601B
CN112716601B CN202011625559.5A CN202011625559A CN112716601B CN 112716601 B CN112716601 B CN 112716601B CN 202011625559 A CN202011625559 A CN 202011625559A CN 112716601 B CN112716601 B CN 112716601B
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stent
blood vessel
shell
vascular
tumor
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CN112716601A (en
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金肜伯
冷晓畅
向建平
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Arteryflow Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • A61B17/12118Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm for positioning in conjunction with a stent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • A61B17/12145Coils or wires having a pre-set deployed three-dimensional shape
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/107Visualisation of planned trajectories or target regions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/108Computer aided selection or customisation of medical implants or cutting guides

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Abstract

The application relates to a simulation method, a simulation device, computer equipment and a storage medium for rapid release of a vascular stent. The method comprises the following steps: constructing a vascular stent and a three-dimensional model of a compressor for simulation calculation, wherein the vascular stent is circumferentially provided with openings; compressing the blood vessel stent by a compressor so that one side of the opening of the blood vessel stent is curled and overlapped towards the inside of the other side and assumes a compressed state; embedding the blood vessel stent into a first shell in a compressed state to form a whole and using the blood vessel stent as a stent conveying system, wherein the first shell is cylindrical; the stent conveying system extends into a second shell and moves towards the far end until reaching a preset position, the second shell is cylindrical, the inner diameter of the second shell is matched with that of the tumor-carrying blood vessel, and the extension trend of the second shell is consistent with that of the tumor-carrying blood vessel; releasing the compression state of the blood vessel stent and further expanding the blood vessel stent to be attached to the tumor-carrying blood vessel. By adopting the method, the simulation speed can be improved, and the practicability and the accuracy are considered.

Description

Simulation method and device for rapid release of vascular stent, computer equipment and storage medium
Technical Field
The present application relates to the field of transformed medicine, and in particular, to a method and an apparatus for simulating rapid release of a vascular stent, a computer device, and a storage medium.
Background
Intracranial aneurysms are pathological bulges of the intracranial arterial wall, which are common in arterial bifurcations of the cerebrovascular willis ring. Aneurysms affect approximately 5% of all humans. The consequences of aneurysm rupture are fatal, with about 50% being non-viable, and varying degrees of physical dysfunction remaining.
Coil embolization is currently the most important method of treating aneurysms. The treatment procedure involves releasing a series of coils into the lumen of the aneurysm to reduce intratumoral blood flow by embolizing the aneurysm. The coil filling causes thrombosis in the subsequent aneurysm, eventually embolizing the aneurysm to isolate the aneurysm from blood circulation. For wide-necked aneurysms, a mesh-phobic stent is often placed in the parent vessel to prevent the coil from falling out of the aneurysm cavity into the parent vessel, a procedure called stent-assisted coil embolization. In the prior art, a dense mesh stent is used for remodeling a parent artery to embolize a cerebral aneurysm, and the principle is that the dense mesh stent with the coverage rate of a metal mesh of about 30-35% is placed to reduce the blood flow speed and the blood flow volume entering an aneurysm cavity, so that thrombus is formed in the aneurysm cavity. The dense mesh stent is particularly effective for large aneurysms, wide-neck aneurysms and other complex aneurysms, and sometimes a small number of spring rings can be placed at the same time when the dense mesh stent is implanted.
Prospective randomized multi-center clinical trials have shown that coil and stent interventional procedures have better outcomes for ruptured and unbroken aneurysms than traditional craniotomy procedures (clamping of the aneurysm by an aneurysm clip). However, one of the biggest weaknesses of coil embolization is the high rate of recurrence, up to 30%, and the need for retreatment of these recurrent aneurysms. The mechanism of recurrence of coil embolization is not fully understood at present, but from intuitive and extensive academic studies, it has been shown that recurrence following coil or stent-assisted coil embolization is closely related to changes in hemodynamics.
Computational Fluid Dynamics (CFD) based on medical images is widely used in hemodynamic analysis before and after aneurysm treatment. However, computational fluid dynamics simulation requires accurate coil, stent or dense mesh stent geometry after intravascular release. This problem is the challenge of current virtual release simulation calculations for coils and stents because previous methods do not allow for rapid and accurate acquisition of the three-dimensional structure of coils and stents after their actual release.
At present, the simulation method of intracranial aneurysm has a porous medium-based method and a quick release method. For example, publication No. CN103198202a describes a method for releasing an aneurysm-carrying stent based on a mathematical model expansion method. Although these methods are relatively fast, their accuracy is not satisfactory for subsequent hemodynamic analysis. The application of traditional finite element algorithms in virtual treatment of aneurysm stents and coils is described in the patent literature of international patent application (PTC/US 2015/012941). The traditional method based on finite element is accurate, the simulation process is carried out according to the real process of stent clamping, conveying and releasing, the method can accurately calculate the mechanical and mechanical characteristics of the stent in the releasing process, however, the calculation time is very long, and therefore, the method is limited in practical clinical application. For example, the HiFiVS calculation based on the finite element method takes more than 100 hours in the process of calculating the delivery of the dense mesh stent, is time-consuming, uneconomical and difficult to meet the requirement of timeliness in clinic.
Disclosure of Invention
In view of the above, there is a need to provide a rapid release simulation method, device, computer device and storage medium for vascular stents, which can improve the calculation speed and ensure the accuracy.
A method for simulating rapid release of a stent, the method comprising:
constructing a vascular stent and a three-dimensional model of a compressor for simulation calculation, wherein the vascular stent is circumferentially provided with openings;
compressing the blood vessel stent by a compressor so that one side of the opening of the blood vessel stent is curled and overlapped towards the inside of the other side and assumes a compressed state;
embedding the vascular stent in a first shell under a compressed state to form a whole and using the vascular stent as a stent delivery system, wherein the first shell is cylindrical;
the stent conveying system extends into a second shell and moves towards the far end until reaching a preset position, the second shell is cylindrical, the inner diameter of the second shell is matched with that of the tumor-carrying blood vessel, and the extension trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
releasing the compressed state of the blood vessel stent, and further expanding the blood vessel stent to be attached to the tumor-carrying blood vessel.
Optionally, when the compressor compresses the blood vessel stent, the open side of the blood vessel stent is fixed, and the other side of the blood vessel stent is curled towards the inside of the fixed side, the cross section of the blood vessel stent is in a spiral shape, and the number of turns of the spiral shape is at least half of that of the spiral shape.
Optionally, the outer diameter of the first shell is larger than the outer diameter of the compressed blood vessel stent, and the inner diameter of the first shell is smaller than the inner diameter of the compressed blood vessel stent.
Optionally, the stent delivery system is moved within the second housing, the vessel stent and the first housing remain relatively fixed.
Optionally, the second housing is constructed by: obtaining the central line of the parent artery, and sweeping along the central line to generate a cylindrical second shell.
Optionally, the inner diameter of the second housing is larger than the outer diameter of the first housing.
Optionally, the second housing includes an extension portion extending from the proximal end to the distal end in the parent vessel in the length direction, and a portion extending linearly from the proximal end back to the distal end.
The application provides a analogue means of quick release of vascular support, includes:
the device comprises a construction module, a calculation module and a display module, wherein the construction module is used for constructing a blood vessel stent and a three-dimensional model used for simulation calculation by a compressor, and the blood vessel stent is circumferentially provided with openings;
the compression module is used for compressing the blood vessel stent by using the compressor so that one side of the opening of the blood vessel stent is curled and overlapped towards the inside of the other side of the opening of the blood vessel stent and takes a compressed state;
the stent delivery system forming module is used for embedding the vascular stent into a first shell in a compressed state to form a whole and is used as a stent delivery system, wherein the first shell is cylindrical;
the moving module is used for extending the stent conveying system into a second shell and moving the stent conveying system to the far end until the stent conveying system reaches a preset position, the second shell is in a cylindrical shape matched with the inner diameter of the tumor-carrying blood vessel, and the extension trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
and the release module is used for releasing the compression state of the blood vessel stent so as to further expand the blood vessel stent to be attached to the tumor-carrying blood vessel.
A computer device comprising a memory and a processor, the memory storing a computer program, the processor implementing the following steps when executing the computer program:
constructing a vascular stent and a three-dimensional model of a compressor for simulation calculation, wherein the vascular stent is circumferentially provided with openings;
compressing the vascular stent by a compressor so that one side of the opening of the vascular stent is curled and overlapped towards the inside of the other side and assumes a compressed state;
embedding the vascular stent in a first shell under a compressed state to form a whole and using the vascular stent as a stent delivery system, wherein the first shell is cylindrical;
the stent conveying system extends into a second shell and moves towards the far end until reaching a preset position, the second shell is cylindrical, the inner diameter of the second shell is matched with that of the tumor-carrying blood vessel, and the extension trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
releasing the compressed state of the blood vessel stent, and further expanding the blood vessel stent to be attached to the tumor-carrying blood vessel.
A computer-readable storage medium, on which a computer program is stored which, when executed by a processor, carries out the steps of:
constructing a vascular stent and a three-dimensional model of a compressor for simulation calculation, wherein the vascular stent is circumferentially provided with openings;
compressing the blood vessel stent by a compressor so that one side of the opening of the blood vessel stent is curled and overlapped towards the inside of the other side and assumes a compressed state;
embedding the vascular stent in a first shell under a compressed state to form a whole and using the vascular stent as a stent delivery system, wherein the first shell is cylindrical;
the stent conveying system extends into a second shell and moves towards the far end until reaching a preset position, the second shell is cylindrical, the inner diameter of the second shell is matched with that of the tumor-carrying blood vessel, and the extension trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
releasing the compressed state of the blood vessel stent, and further expanding the blood vessel stent to be attached to the tumor-carrying blood vessel.
According to the simulation method, the simulation device, the computer equipment and the storage medium for the quick release of the vascular stent, the selection of the optimal aneurysm treatment scheme is obtained through further calculation and the output of relevant indexes, and accurate medical treatment is carried out. And the rapid virtual implantation method of the stent of the traditional finite element method is optimized, the accuracy of the simulation structure is further improved, and simultaneously, the three-dimensional model after the stent is released can be rapidly obtained, so that the balance between the accuracy and the effectiveness is achieved.
Drawings
FIG. 1 is a schematic flow chart illustrating a method for simulating rapid release of a stent in an embodiment;
FIG. 2 is a schematic view of a process for compressing a stent in one embodiment by a compressor;
FIG. 3 is a schematic view of the stent delivery system assembled into the second housing in one embodiment;
FIG. 4 is another perspective view of the stent delivery system assembled into the second housing in one embodiment;
FIG. 5 is a schematic view of the stent delivery system moving to the second housing straight section in one embodiment;
FIG. 6 is a schematic view of the stent delivery system moving to the second housing extension in one embodiment;
FIG. 7 is a schematic view of a stent delivery system in a compressed state in a parent vessel in accordance with an embodiment;
FIG. 8 is a schematic illustration of a stent delivery system in a released state in a parent vessel in one embodiment;
FIG. 9 is a block diagram showing the structure of a rapid release simulator for a stent in one embodiment;
FIG. 10 is a diagram showing an internal structure of a computer device according to an embodiment.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
As shown in fig. 1-8, a simulation method for rapid release of a vascular stent is provided, which comprises the following steps:
step S100, constructing a vascular stent and a three-dimensional model of a compressor for simulation calculation, wherein the vascular stent is circumferentially provided with openings;
step S120, compressing the blood vessel stent by using a compressor so that one side of the opening of the blood vessel stent is curled and overlapped towards the inside of the other side of the opening of the blood vessel stent and is in a compressed state;
step S140, embedding the vascular stent into a first shell in a compressed state to form a whole and using the vascular stent as a stent conveying system, wherein the first shell is cylindrical;
step S160, extending the stent conveying system into a second shell and moving the second shell to the far end until the stent conveying system reaches a preset position, wherein the second shell is in a cylindrical shape matched with the inner diameter of the tumor-carrying blood vessel, and the extension trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
and step S180, releasing the compression state of the blood vessel stent, and further expanding the blood vessel stent to be attached to the tumor-carrying blood vessel.
Since the present application relates to simulation calculation and display, components such as the vascular stent and an in vivo environment are three-dimensional models without special statement, and of course, in the following embodiments, a computer environment on which the simulation release method of the present application operates is mentioned, and a processor or a memory and the like are all physical hardware.
Before the simulation calculation is carried out, the three-dimensional model of the designed mechanical or human body structure can be constructed in advance, the interventional device is mainly applied to a blood vessel stent, and the current stent for treating intracranial aneurysm is mainly a self-expanding stent which is divided into a laser carving stent and a weaving type stent. The simulation method referred to in this application is mainly applied to Solitaire stents (Medtronic corporation, usa), which belong to laser engraved stents. The three-dimensional model can be constructed by software for this type of stent.
The tumor-bearing blood vessel is an interesting intercepting segment, and the length of the tumor-bearing blood vessel, namely the length involved in the simulation calculation, is about the same as the length of the blood vessel stent after the blood vessel stent is completely released.
Since the Solitaire stent is a stent with one side completely open in the circumferential direction, when the stent is released in a tumor-carrying vessel, the overlap is generated, and the overlap is determined by the diameter of the tumor-carrying vessel and the size of the stent.
In step S100, in the three-dimensional construction, the vessel stent is constructed in a circumferentially unclosed state, as shown in fig. 2, wherein the right side is a schematic cross-sectional view of the vessel stent in different states.
In step S120, when the blood vessel stent is compressed by the compressor, the open side of the blood vessel stent is fixed and the other side is curled toward the inside of the fixed side, and the cross section of the blood vessel stent is spiral, and the number of turns of the spiral is at least half of a turn.
When the compressor compresses the blood vessel stent, the compressor is utilized to gradually fold the blood vessel stent in the radial direction, namely, displacement boundary conditions are applied to the outer wall of the blood vessel stent until the inner diameter of the blood vessel stent reaches preset values, as shown in fig. 2, the conditions are respectively applied to the blood vessel stent in a stress-free state from top to bottom, and finally preset data are reached.
The device can be generally divided into two parts in the process, namely, the compressor is slowly subjected to displacement loading, and the compressor is firstly contacted with the surface of the peripheral wall of the blood vessel stent; and then the displacement loading speed is increased, and the vascular stent is compressed. As the compressor compresses the blood vessel support, the number of turns of the spiral shape of the cross section of the blood vessel support is increased, and the inner diameter of the blood vessel support is reduced until the inner diameter reaches a preset value.
Before the vascular stent is compressed by the compressor, the compressor in an unstressed state is sleeved on the periphery of the vascular stent. In order to prevent causing the unconvergence of calculation in the subsequent finite element analysis calculation, the inner peripheral wall of the compressor and the outer peripheral wall of the blood vessel stent are kept with a gap, and the gap is 1-2 times of the wall thickness of the blood vessel stent.
In the embodiment, the contact assembly of the simulated blood vessel stent and the catheter in the stent conveying process in the traditional finite element method is eliminated, and the compressed blood vessel stent is fixed in the first shell with a certain thickness to quickly convey the blood vessel stent.
Because the catheter is an indispensable intervention device for transporting the vascular stent in actual operation, the catheter can be constructed in three dimensions in a delivery model to simulate the real situation, but the catheter has different models, so that a large amount of calculation is needed during the three-dimensional construction, and therefore in the application, the calculation resources are greatly saved in the mode that the compressed vascular stent directly generates a corresponding shell. In addition, the wall of the catheter is thin, and when the vascular stent is conveyed, the tumor-carrying blood vessel with a complex path can cause the vascular stent to be difficult to keep the original state, so that the simulation process speed is slow.
In step S140, in order to prevent kinking of the vascular stent during the transportation in the tortuous tumor-bearing blood vessel, a first cylindrical shell with a thickness is formed by software and covers the entire vascular stent to form a whole body.
In order to make the blood vessel support be completely embedded in the first shell body, the external diameter of the first shell body is greater than the external diameter of the compressed blood vessel support, and its internal diameter is less than the internal diameter of the compressed blood vessel support. And the length of the first shell is greater than the length of the blood vessel stent. The gaps between the outer peripheral wall of the blood vessel support and the outer peripheral wall of the first shell and between the inner peripheral wall of the blood vessel support and the inner peripheral wall of the first shell are generally multiples of the wall thickness of the blood vessel support.
And embedding the compressed vascular stent into the first shell, and binding the vascular stent and the first shell together through finite element calculation software to form a stent delivery system. And, when the subsequent stent delivery system moves distally along the axis of the guide member, the vascular stent and the first housing remain relatively fixed.
In this embodiment, a method of freely pushing the stent delivery system in the tumor-laden blood vessel from the proximal end to the distal end in the process of delivering the stent of the conventional finite element simulation blood vessel is further improved, and a second shell which is consistent with the tumor-laden blood vessel in extension is used for delivery guidance, so that the extension path of the tumor-laden blood vessel is further simplified, and the delivery speed is increased.
In step S160, when the second shell is generated, the center line of the parent blood vessel is obtained by software, and the second shell having a cylindrical shape is generated by sweeping along the center line, and the extending path of the second shell is matched with the parent blood vessel.
In this embodiment, the second housing has little thickness and is a very thin shell, the inner diameter of the second housing is slightly larger than the outer diameter of the stent delivery system, i.e., the first housing, and the inner diameter of the second housing is not changed, so that the second housing forms a cylindrical channel in the parent vessel, and the parent vessel path is simplified. When the stent delivery system moves in the tumor-bearing blood vessel, the second shell restrains the moving path, so that the stent delivery system can rapidly reach a preset position to avoid a large amount of calculation and analysis when the stent delivery system freely advances in the roundabout tumor-bearing blood vessel, as shown in fig. 3-4, wherein 1 indicates the blood vessel stent in a compressed state, 2 indicates the first shell, and 3 indicates the second shell.
Since the stent delivery system has a straight axis during delivery, in order to facilitate the stent delivery system to enter the parent vessel, the second housing includes a portion extending from the proximal end to the distal end in the parent vessel and a portion extending straight from the proximal end back to the distal end. Thus, when the stent delivery system is delivered, the system can be assembled to the linearly extended part of the second shell in advance and then pushed towards the distal end of the tumor-bearing blood vessel under the constraint of the second shell, so as to complete the delivery of the blood vessel stent, as shown in fig. 5-6.
And applying a displacement boundary condition parallel to the axial direction along the axial direction of the second shell by the proximal end of the shell during the stent conveying process, so that the stent conveying system slowly moves forwards in the second shell until the distal end of the blood vessel stent reaches a preset position. During the process of delivering the blood vessel stent, the extending path of the second shell is simplified into a rigid body and is fixed.
After the delivery is completed, the parent artery is simplified into a rigid body and fixed, and pressure is applied to the inner wall of the stent to slowly expand the stent until the stent is completely attached to the wall, as shown in figures 7-8.
When the radial gap between the vascular stent and the tumor-carrying blood vessel is small, the vascular stent is further expanded until the vascular stent is completely attached to the inner wall of the tumor-carrying blood vessel, and if the local gap is large, the vascular stent may not be completely attached to the inner wall of the tumor-carrying blood vessel at the part, so that the attachment rate of the vascular stent and the inner wall of the tumor-carrying blood vessel and the coverage rate of the vascular stent on the inner wall of the tumor-carrying blood vessel are necessary to be calculated for effect evaluation.
It should be understood that, although the steps in the flowchart of fig. 1 are shown in order as indicated by the arrows, the steps are not necessarily performed in order as indicated by the arrows. The steps are not limited to being performed in the exact order illustrated and, unless explicitly stated herein, may be performed in other orders. Moreover, at least some of the steps in fig. 1 may include multiple sub-steps or multiple stages that are not necessarily performed at the same time, but may be performed at different times, and the order of performing the sub-steps or stages is not necessarily sequential, but may be performed alternately or alternately with other steps or at least some of the sub-steps or stages of other steps.
According to the simulation method for the rapid release of the intravascular stent, the contraction mode of the intravascular stent in an actual state is simulated by improving the traditional finite element method, the first shell with a certain thickness is used for replacing a catheter, and the cylindrical second shell is directly generated along the central line of the parent artery, so that the intravascular stent conveying device is pushed in the second shell for simplifying the parent vessel path, and a large amount of calculation in the free pushing process of the stent conveying system is avoided. The improvement of the above aspects greatly accelerates the simulation speed of the stent, greatly shortens the time, obtains a more accurate three-dimensional model after the stent is released, obtains the change condition of the hemodynamics through the calculation of CFD, and carries out personalized and precise medical treatment.
In one embodiment, as shown in fig. 9, there is provided a rapid release simulator of a stent, comprising: a build module 200, a compression module 220, a stent delivery system formation module 240, a movement module 260, and a release module 280, wherein:
a construction module 200 for constructing a vascular stent having openings circumferentially and a three-dimensional model of a compressor for simulation calculations;
the compression module 220 is used for compressing the blood vessel stent by using a compressor so that one side of the opening of the blood vessel stent is curled and overlapped towards the inside of the other side, and the blood vessel stent is in a compressed state;
a stent delivery system forming module 240 for embedding the vascular stent in a compressed state into a first shell to form a whole and serving as a stent delivery system, wherein the first shell is cylindrical;
the moving module 260 is used for extending the stent delivery system into a second shell and moving the stent delivery system to the far end until the stent delivery system reaches a preset position, the second shell is in a cylindrical shape matched with the inner diameter of the tumor-carrying blood vessel, and the extension trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
and the release module 280 is used for releasing the compressed state of the blood vessel stent so as to further expand the blood vessel stent to be attached to the tumor-carrying blood vessel.
For specific limitations of the simulation apparatus for rapid release of the blood vessel stent, reference may be made to the above limitations of the simulation method for rapid release of the blood vessel stent, which are not described herein again. The modules in the above-mentioned vascular stent rapid-release simulation device can be wholly or partially realized by software, hardware and a combination thereof. The modules can be embedded in a hardware form or independent from a processor in the computer device, and can also be stored in a memory in the computer device in a software form, so that the processor can call and execute operations corresponding to the modules.
In one embodiment, a computer device is provided, which may be a terminal, and its internal structure diagram may be as shown in fig. 10. The computer device comprises a processor, a memory, a network interface, a display screen and an input device which are connected through a system bus. Wherein the processor of the computer device is configured to provide computing and control capabilities. The memory of the computer device comprises a nonvolatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of an operating system and computer programs in the non-volatile storage medium. The network interface of the computer device is used for communicating with an external terminal through a network connection. The computer program is executed by a processor to implement a method of simulating rapid release of a stent. The display screen of the computer equipment can be a liquid crystal display screen or an electronic ink display screen, and the input device of the computer equipment can be a touch layer covered on the display screen, a key, a track ball or a touch pad arranged on a shell of the computer equipment, an external keyboard, a touch pad or a mouse and the like.
Those skilled in the art will appreciate that the architecture shown in fig. 10 is merely a block diagram of some of the structures associated with the disclosed aspects and is not intended to limit the computing devices to which the disclosed aspects apply, as particular computing devices may include more or less components than those shown, or may combine certain components, or have a different arrangement of components.
In one embodiment, a computer device is provided, comprising a memory and a processor, the memory having a computer program stored therein, the processor implementing the following steps when executing the computer program:
constructing a three-dimensional model of a blood vessel stent and a compressor for simulation calculation, wherein the blood vessel stent is circumferentially provided with openings;
compressing the blood vessel stent by a compressor so that one side of the opening of the blood vessel stent is curled and overlapped towards the inside of the other side and assumes a compressed state;
embedding the vascular stent in a first shell under a compressed state to form a whole and using the vascular stent as a stent delivery system, wherein the first shell is cylindrical;
the stent conveying system extends into a second shell and moves towards the far end until reaching a preset position, the second shell is cylindrical, the inner diameter of the second shell is matched with that of the tumor-carrying blood vessel, and the extension trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
releasing the compressed state of the blood vessel stent, and further expanding the blood vessel stent to be attached to the tumor-carrying blood vessel.
In one embodiment, a computer-readable storage medium is provided, having a computer program stored thereon, which when executed by a processor, performs the steps of:
constructing a three-dimensional model of a blood vessel stent and a compressor for simulation calculation, wherein the blood vessel stent is circumferentially provided with openings;
compressing the blood vessel stent by a compressor so that one side of the opening of the blood vessel stent is curled and overlapped towards the inside of the other side and assumes a compressed state;
embedding the vascular stent in a first shell under a compressed state to form a whole and using the vascular stent as a stent delivery system, wherein the first shell is cylindrical;
the stent delivery system is inserted into a second shell and moves towards the far end until reaching a preset position, the second shell is cylindrical, the inner diameter of the second shell is matched with that of the tumor-carrying blood vessel, and the extension trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
and releasing the compression state of the blood vessel stent, so that the blood vessel stent is further expanded to be attached to the tumor-carrying blood vessel.
It will be understood by those skilled in the art that all or part of the processes of the methods of the embodiments described above may be implemented by hardware instructions of a computer program, which may be stored in a non-volatile computer-readable storage medium, and when executed, may include the processes of the embodiments of the methods described above. Any reference to memory, storage, database, or other medium used in the embodiments provided herein may include non-volatile and/or volatile memory, among others. Non-volatile memory can include read-only memory (ROM), programmable ROM (PROM), electrically Programmable ROM (EPROM), electrically Erasable Programmable ROM (EEPROM), or flash memory. Volatile memory can include Random Access Memory (RAM) or external cache memory. By way of illustration and not limitation, RAM is available in a variety of forms such as Static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double Data Rate SDRAM (DDRSDRAM), enhanced SDRAM (ESDRAM), synchronous Link DRAM (SLDRAM), rambus (Rambus) direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM).
The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (9)

1. The simulation method for the rapid release of the vascular stent is characterized by comprising the following steps:
constructing a three-dimensional model of a blood vessel stent and a compressor for simulation calculation, wherein the blood vessel stent is a laser-engraved stent and is provided with an opening in the circumferential direction;
compressing the vascular stent by a compressor so that one side of the opening of the vascular stent is curled and overlapped towards the inside of the other side and assumes a compressed state;
embedding the vascular stent into a first shell in a compressed state to form a whole and using the vascular stent as a stent conveying system, wherein the first shell is cylindrical, the vascular stent is wrapped by the first shell, the outer diameter of the first shell is larger than that of the compressed vascular stent, and the inner diameter of the first shell is smaller than that of the compressed vascular stent;
the stent delivery system is inserted into a second shell and moves towards the far end until reaching a preset position, the second shell is cylindrical, the inner diameter of the second shell is matched with that of the tumor-carrying blood vessel, and the extension trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
and releasing the compression state of the blood vessel stent, and applying pressure on the inner wall of the blood vessel stent to further expand the blood vessel stent to be attached to the tumor-carrying blood vessel.
2. The method for simulating rapid release of a vascular stent as claimed in claim 1, wherein when the compressor compresses the vascular stent, the open side of the vascular stent is fixed and the other side is curled inwards towards the fixed side, the cross section of the vascular stent is in a spiral shape, and the number of turns of the spiral shape is at least half of a turn.
3. The method according to claim 1, wherein the stent and the first housing are kept relatively fixed while moving the stent delivery system in the second housing.
4. The method for simulating rapid release of a vascular stent as claimed in claim 1, wherein the constructing the second shell comprises: obtaining the central line of the parent artery, and sweeping along the central line to generate a cylindrical second shell.
5. The method for simulating rapid release of a vascular stent as defined in claim 1, wherein the second shell has an inner diameter larger than an outer diameter of the first shell.
6. The method for simulating rapid release of a stent graft of claim 1, wherein the second shell comprises a section extending from the proximal end to the distal end in the parent vessel and a section extending straight from the proximal end to the distal end.
7. A rapid release simulator for vascular stents, comprising:
the device comprises a construction module, a simulation module and a control module, wherein the construction module is used for constructing a blood vessel stent and a three-dimensional model of a compressor for simulation calculation, and the blood vessel stent is a laser carving stent and is provided with an opening in the circumferential direction;
the compression module is used for compressing the blood vessel stent by using the compressor so that one side of the opening of the blood vessel stent is curled and overlapped towards the inside of the other side of the opening of the blood vessel stent and takes a compressed state;
the stent delivery system forming module is used for embedding the vascular stent into a first shell in a compressed state to form a whole and using the vascular stent as a stent delivery system, wherein the first shell is cylindrical, the vascular stent is wrapped by the first shell, the outer diameter of the first shell is larger than that of the compressed vascular stent, and the inner diameter of the first shell is smaller than that of the compressed vascular stent;
the moving module is used for extending the stent conveying system into a second shell and moving the stent conveying system to the far end until the stent conveying system reaches a preset position, the second shell is in a cylindrical shape matched with the inner diameter of the tumor-carrying blood vessel, and the extending trend of the cylinder is consistent with that of the tumor-carrying blood vessel;
and the release module is used for releasing the compression state of the blood vessel stent and applying pressure on the inner wall of the blood vessel stent to further expand the blood vessel stent to be attached to the tumor-carrying blood vessel.
8. A computer arrangement comprising a memory and a processor, the memory storing a computer program, wherein the processor when executing the computer program performs the steps of the method for simulated release of a vessel stent according to any of claims 1 to 6.
9. A computer-readable storage medium, on which a computer program is stored which, when being executed by a processor, carries out the steps of the method for simulated release of a vessel stent according to any one of claims 1 to 6.
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