CN112690754A - OCTA imaging optical path system with double working modes - Google Patents
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- 238000003384 imaging method Methods 0.000 title claims abstract description 38
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- 208000005590 Choroidal Neovascularization Diseases 0.000 description 1
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- 208000003435 Optic Neuritis Diseases 0.000 description 1
- 206010036590 Premature baby Diseases 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
- A61B3/1225—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation
- A61B3/1233—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation for measuring blood flow, e.g. at the retina
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
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Abstract
The invention discloses an OCTA imaging optical path system with double working modes. The OCTA imaging optical path system comprises a reference arm optical path and at least two sample arm optical paths matched with a light source and a coupler, wherein the coupler is at least used for dividing a source light beam emitted by the light source into a first sub-beam and a second sub-beam, and the first sub-beam and the second sub-beam are respectively and correspondingly input into the reference arm optical path and the sample arm optical path. The embodiment of the invention provides an OCTA imaging optical path system with double working modes, which is provided with two sample arm optical paths with different working modes, wherein the two sample arm optical paths are matched with one reference arm optical path, so that the switching of the different working modes of the OCTA sample arm optical path can be realized, a single device has two different using modes, the fixed data acquisition mode and the handheld data acquisition mode can be switched at will, the using efficiency and the performance of the device are greatly improved, the requirements of different types of patients can be met, and the device cost is greatly saved.
Description
Technical Field
The invention relates to an OCTA imaging optical path system, in particular to an OCTA imaging optical path system with double working modes, and belongs to the technical field of optical coherence tomography.
Background
Fundus coherence tomography (OCTA) is a non-invasive imaging method, and the technical principle is based on the existence of blood cells which continuously flow in a fundus blood vessel and the coherence tomography imaging is carried out on a cross-sectional structure under the micrometer-scale resolution; obtaining moving blood cells, namely blood flow signals, through special computer image algorithm processing; and three-dimensional reconstruction is carried out on the obtained vascular structure signals, and fundus vascular images are presented layer by layer in the form of a coronal plane (en face), so that images of different tissue structures of the fundus are obtained. Based on the characteristic of OCTA, the method can be applied to diagnosis and treatment of retinal vascular diseases, glaucoma, idiopathic macular foveal capillary vasodilation, diabetic retinopathy, choroidal neovascularization, optic neuritis and other fundus diseases.
At present, most of the commercialized ophthalmic OCTA devices in the market perform data acquisition in a single mode fixedly installed on a desktop, such as for common ophthalmic patients, and they can meet clinical requirements on such a single patient population. However, when a general patient needs to be treated and special population patients such as anesthesia, severe patients in bed, retinopathy premature babies, infants, and the like need to be treated, other OCTA examination devices need to be additionally equipped, however, a plurality of OCTA imaging devices not only occupy space and increase the purchase cost of the devices, but also increase the maintenance cost of the devices.
Disclosure of Invention
The invention mainly aims to provide an OCTA imaging optical path system with double working modes so as to overcome the defects in the prior art.
In order to achieve the purpose, the technical scheme adopted by the invention comprises the following steps:
the invention provides an OCTA imaging optical path system with double working modes, which comprises a reference arm optical path and at least two sample arm optical paths, wherein the reference arm optical path and the at least two sample arm optical paths are matched with a light source and a coupler;
when one of the sample arm light paths and the reference arm light path work in a matched mode, the OCTA imaging light path system can realize a fixed acquisition mode, and when the other sample arm light path and the reference arm light path work in a matched mode, the OCTA imaging light path system can realize a handheld acquisition mode.
Compared with the prior art, the invention has the advantages that: the embodiment of the invention provides an OCTA imaging optical path system with double working modes, which is provided with two sample arm optical paths with different working modes, wherein the two sample arm optical paths are matched with one reference arm optical path, so that the switching of the different working modes of the OCTA sample arm optical path can be realized, a single device has two different using modes, the fixed data acquisition mode and the handheld data acquisition mode can be switched at will, the using efficiency and the using performance of the device are greatly improved, the requirements of different types of patients can be met, and the device cost is greatly saved.
Drawings
FIG. 1 is a schematic diagram of a dual-mode OCTA imaging optical path system according to an exemplary embodiment of the present invention;
fig. 2 is a schematic diagram of a fixed mount or hand held sample arm optical path provided in an exemplary embodiment of the invention.
Detailed Description
In view of the deficiencies in the prior art, the inventors of the present invention have made extensive studies and extensive practices to provide technical solutions of the present invention. The technical solution, its implementation and principles, etc. will be further explained as follows.
The embodiment of the invention provides an optical coherence tomography imaging-based multi-working-mode OCTA imaging system, which comprises a reference arm and two sample arms, wherein the two sample arms share the reference arm, so that the two sample arms with different working modes can be conveniently, quickly and randomly switched, and a single device has two different working modes, such as a fixed acquisition mode and a handheld acquisition mode.
The embodiment of the invention provides an OCTA imaging optical path system with double working modes, which comprises a reference arm optical path and at least two sample arm optical paths, wherein the reference arm optical path and the at least two sample arm optical paths are matched with a light source and a coupler;
when one of the sample arm light paths and the reference arm light path work in a matched mode, the OCTA imaging light path system can realize a fixed acquisition mode, and when the other sample arm light path and the reference arm light path work in a matched mode, the OCTA imaging light path system can realize a handheld acquisition mode.
Furthermore, the at least two sample arm optical paths are connected with the coupler through an optical switch, and the second split beam can be correspondingly input into an appointed sample arm optical path by switching the optical switch, so that the appointed sample optical path and the reference arm optical path work in a matching way and a handheld acquisition mode or a fixed acquisition mode is realized.
Furthermore, the reference arm light path comprises a third collimator, a diaphragm and a reflecting mirror, and the first split beam output from the coupler sequentially passes through the collimator and the diaphragm and then reaches the reflecting mirror.
Further, at least two sample arm light paths include at least one fixed mounting formula sample arm light path and at least one hand-held type sample arm light path, fixed mounting formula sample arm light path and hand-held type sample arm light path set up in parallel, just fixed mounting formula sample arm light path and to hand-held type sample arm light path can not simultaneous working.
Furthermore, the fixed mounting type sample arm light path comprises a first collimator, a first scanning galvanometer, a first lens and a second lens, the second sub-beam is incident to the first scanning galvanometer after passing through the first collimator, and emergent light of the first scanning galvanometer sequentially passes through the first lens and the second lens and is incident to human eyes.
Furthermore, the fixed mounting type sample arm light path comprises a second collimator, a second scanning galvanometer, a second lens and a second lens, the second split beam enters the second scanning galvanometer after passing through the second collimator, and emergent light of the second scanning galvanometer sequentially passes through the second lens and enters human eyes.
Further, OCTA imaging optical path system of two mode of doing includes sample arm and reference arm, the sample arm includes fixed mounting formula sample arm light path, hand-held type sample arm light path and photoswitch, the coupler warp photoswitch with fixed mounting formula sample arm light path, hand-held type sample arm light path are connected, the reference arm includes the reference arm light path.
Further, the source beam is split into a first split beam and a second split beam in a 3:1 ratio.
Further, the dual-operation mode OCTA imaging optical path system further includes: the light source and the image acquisition mechanism are respectively connected with the coupler, the coupler is connected with the sample arm light path and the reference arm light path, and the image acquisition mechanism is at least used for acquiring light beams reflected by the reference arm light path.
Further, the image acquisition mechanism comprises a CCD high-speed camera.
Further, the light source comprises a low-coherence broadband light source, and the wavelength of the low-coherence broadband light source is 850nm and the power of the low-coherence broadband light source is 15 mW.
The technical solution, the implementation process and the principle thereof will be further explained with reference to the drawings, and unless otherwise specified, various components used in the embodiments of the present invention may be known to those skilled in the art and may be commercially available.
The embodiment of the invention provides a switchable working mode of an OCTA imaging optical path system with double working modes. The low-coherence broadband light source can adopt a laser light source with the wavelength of 850nm and the power of 15mW, the high-speed camera can be a CCD high-speed camera with the frequency of 250KHz, the optical fiber coupler can be a 2-by-2 broadband coupler with the wavelength of 75:25, the optical fiber coupler can divide a source light beam emitted by the low-coherence broadband light source into two beams, 75% of the light beam (namely the first light beam) enters the reference arm light path, and 25% of the light beam (namely the second light beam) enters the double-working-mode sample arm light path.
Specifically, the reference arm light path comprises a collimator, a diaphragm and a reflector, the first light beam enters the collimator after being output from the coupler, then passes through the diaphragm and then reaches the reflector, wherein the diaphragm can adjust the luminous flux, so that the light entering the reflector can be adjusted according to experimental needs to meet detection requirements.
Specifically, the dual-working-mode sample arm optical path comprises an optical switch, a fixed-mounting sample arm optical path and a handheld sample arm optical path.
Specifically, the optical switch is a 1 × 2 electric control optical switch, and the optical switch is electronically driven and controlled through a voltage signal, so that the optical signal can be switched to one end of the optical path of the handheld sample arm from the optical path of the fixed mounting type sample arm and one end of the optical path of the fixed mounting type sample arm at will.
Specifically, the fixed-mounting type sample arm optical path comprises a laser collimator, a scanning galvanometer, a lens and an eye lens, and a second light beam is collimated by the laser collimator, reflected by the two-dimensional scanning galvanometer, enters the lens, enters the eye lens, is amplified by the eye lens and enters the eyeball of the human eye; the fixed mounting type sample arm light path can be fixedly mounted on a lifting platform of the ophthalmological equipment or on an adjusting platform of other types of ophthalmological equipment, and a common ophthalmological patient can sit in front of the fixed mounting type sample arm light path statically and can complete detection by adopting the fixed mounting type sample arm light path.
Specifically, the optical path of the handheld sample arm comprises a laser collimator, a scanning galvanometer, a lens and an ocular lens, and a second light beam is collimated by the laser collimator, reflected by the two-dimensional scanning galvanometer, enters the lens, enters the ocular lens, is amplified by the ocular lens and enters the eyeball of the human eye; hand-held type sample arm light path can set up in the small-size box that conveniently holds, and the detection of arbitrary angle direction can be accomplished to operating personnel handheld device, can make special crowd patients such as being in anesthesia, bed severe patient, retinopathy premature infant, infant keep the most comfortable gesture of patient, and operating personnel holds hand-held type sample arm light path box can accomplish the detection to the patient.
Specifically, the scanning galvanometer is a two-dimensional mechanical scanning galvanometer, the ocular lens is an achromatic double cemented lens with f equal to 30, and the lens is an achromatic double cemented lens with f equal to 50.
Referring to fig. 1, a dual-working mode OCTA imaging optical path system 100 includes a high-speed CCD camera 101, a low coherence broadband light source 102, a 90:10 2 x 2 fiber coupler 103, a reference arm 200 and a sample arm 300, where the reference arm 200 includes a collimator 201, a diaphragm 202 and a mirror 203, the sample arm 300 includes a 1 x 2 electrically controlled optical switch 310, a fixed-mounted sample arm optical path 320 and a handheld sample arm optical path 330, and the 1 x 2 electrically controlled optical switch 310 is driven by an electrical signal to connect a connector P of the 1 x 2 electrically controlled optical switch 310 to a connector P1 or a connector P2, so as to control a light beam output from the 2 x 2 fiber coupler 103 to enter the fixed-mounted sample arm optical path 302 or the handheld sample arm optical path 303.
Referring to fig. 2, fig. 2 is a schematic structural diagram of a light path of a fixed-mount or handheld sample arm, where a light beam is collimated by the laser collimator 301, reflected by the two-dimensional scanning galvanometer 302, enters the lens 303, enters the ocular lens 304, and is amplified by the ocular lens 304 and enters the eyeball 305.
Specifically, the fixed sample arm optical path 302 may be installed on a lifting platform of an ophthalmic apparatus, or may be installed on an adjustment platform of other types of ophthalmic apparatuses, and the handheld sample arm optical path 303 may be disposed in a small box convenient for holding by hand, or may be integrally installed on an apparatus similar to a handheld pan-tilt stabilizer.
Specifically, referring again to fig. 1, the low coherence broadband light source 102 emits laser b, and the laser b passes through the 75:25, the 2 x 2 optical fiber coupler 103 divides the laser into two beams, namely a beam c with the proportion of 75% and a beam d with the proportion of 25%, wherein the beam c passes through the diaphragm 202 after being collimated by the collimator 201, and then enters the reflector 203, the reflector 203 reflects the beam c back, and the beam c returns to the 2 x 2 optical fiber coupler 103 along the original path; and the light beam d enters the P joint on the 1 x 2 electronic control switch 310, when a common ophthalmic patient needs to be detected, the 1 x 2 electronic control switch 310 joint P is connected to the P1 joint, the light beam d enters the fixed mounting type sample arm light path 320, the light beam d reaches the eyeball of the detected person through the fixed mounting type sample arm light path 320, is scattered and returns to the 2 x 2 optical fiber coupler 103 along the original light path, and passes 75: the 2 x 2 optical fiber coupler 103 of 25 is converged to form an interference light beam a, then the interference light beam a is detected by the high-speed CCD camera 101, the high-speed CCD camera 101 converts an optical signal into an electric signal, and an OCTA acquisition image is formed after the electric signal is processed by a computer.
When special population patients such as anesthesia, severe patients in bed, retinopathy premature infants, infants and the like need to be detected, the joint P of the 1-x 2 electronic control switch 310 is connected to the joint P2, light beams enter the handheld sample arm light path 330, and the light beams reach eyeballs of the detected person through the handheld sample arm light path 303, are scattered and return, and pass through 75: the 2 x 2 optical fiber coupler 103 of 25 is converged to form an interference light beam a, then the interference light beam a is detected by the high-speed CCD camera 101, the high-speed CCD camera 101 converts an optical signal into an electric signal, and an OCTA acquisition image is formed after the electric signal is processed by a computer.
The embodiment of the invention provides an OCTA imaging optical path system with double working modes, which is provided with two sample arm optical paths with different working modes, wherein the two sample arm optical paths are matched with one reference arm optical path, so that the switching of the different working modes of the OCTA sample arm optical path can be realized, a single device has two different using modes, the fixed data acquisition mode and the handheld data acquisition mode can be switched at will, the using efficiency and the using performance of the device are greatly improved, the requirements of different types of patients can be met, and the device cost is greatly saved.
It should be understood that the above-mentioned embodiments are merely illustrative of the technical concepts and features of the present invention, which are intended to enable those skilled in the art to understand the contents of the present invention and implement the present invention, and therefore, the protection scope of the present invention is not limited thereby. All equivalent changes and modifications made according to the spirit of the present invention should be covered within the protection scope of the present invention.
Claims (10)
1. An OCTA imaging optical path system with double working modes is characterized by comprising a reference arm optical path and at least two sample arm optical paths, wherein the reference arm optical path and the at least two sample arm optical paths are matched with a light source and a coupler;
when one of the sample arm light paths and the reference arm light path work in a matched mode, the OCTA imaging light path system can realize a fixed acquisition mode, and when the other sample arm light path and the reference arm light path work in a matched mode, the OCTA imaging light path system can realize a handheld acquisition mode.
2. The dual mode OCTA imaging optics system of claim 1, wherein: the at least two sample arm optical paths are connected with the coupler through an optical switch, and the second split beam can be correspondingly input into an appointed sample arm optical path by switching the optical switch, so that the appointed sample optical path and the reference arm optical path work in a matched mode and a handheld acquisition mode or a fixed acquisition mode is realized.
3. The OCTA imaging optical path system in dual operating mode as claimed in claim 2, wherein: the reference arm light path comprises a third collimator, a diaphragm and a reflecting mirror, and a first split beam output from the coupler sequentially passes through the collimator and the diaphragm and then reaches the reflecting mirror.
4. The OCTA imaging optical path system in dual operating mode as claimed in claim 2, wherein: at least two sample arm light paths include at least one fixed mounting formula sample arm light path and at least one hand-held type sample arm light path, fixed mounting formula sample arm light path and hand-held type sample arm light path set up in parallel, just fixed mounting formula sample arm light path and to hand-held type sample arm light path can not simultaneous working.
5. The OCTA imaging optical path system in dual operating mode as claimed in claim 4, wherein: the fixed mounting type sample arm light path comprises a first collimator, a first scanning galvanometer, a first lens and a second lens, wherein a second sub-beam enters the first scanning galvanometer after passing through the first collimator, and emergent light of the first scanning galvanometer sequentially passes through the first lens and the second lens and enters human eyes.
6. The OCTA imaging optical path system in dual operating mode as claimed in claim 4, wherein: the fixed mounting type sample arm light path comprises a second collimator, a second scanning galvanometer, a second lens and a second lens, the second split beam enters the second scanning galvanometer after passing through the second collimator, and emergent light of the second scanning galvanometer sequentially passes through the second lens and enters human eyes.
7. The dual mode OCTA imaging optics of claim 4 including a sample arm and a reference arm, said sample arm including a fixed mount sample arm optical path, a hand held sample arm optical path and an optical switch, said coupler being optically connected to said fixed mount sample arm optical path and said hand held sample arm optical path through said optical switch, said reference arm including a reference arm optical path.
8. The OCTA imaging optical path system in dual operating mode as claimed in claim 2, wherein: the source beam is split into a first split beam and a second split beam in a 3:1 ratio.
9. The dual mode OCTA imaging optics system of claim 1, further comprising: the light source and the image acquisition mechanism are respectively connected with the coupler, the coupler is connected with the sample arm light path and the reference arm light path, and the image acquisition mechanism is at least used for acquiring light beams reflected by the reference arm light path.
10. The dual mode OCTA imaging optics system of claim 9, wherein: the light source comprises a low-coherence broadband light source, and the wavelength of the low-coherence broadband light source is 850nm and the power of the low-coherence broadband light source is 15 mW.
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| CN202011526479.4A CN112690754A (en) | 2020-12-22 | 2020-12-22 | OCTA imaging optical path system with double working modes |
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| CN202011526479.4A CN112690754A (en) | 2020-12-22 | 2020-12-22 | OCTA imaging optical path system with double working modes |
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