CN112674072B - Tissue sample storage method for oncology department - Google Patents

Tissue sample storage method for oncology department Download PDF

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Publication number
CN112674072B
CN112674072B CN202011517471.1A CN202011517471A CN112674072B CN 112674072 B CN112674072 B CN 112674072B CN 202011517471 A CN202011517471 A CN 202011517471A CN 112674072 B CN112674072 B CN 112674072B
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magnetic ring
bottle body
sliding
rod
overturning
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CN112674072A (en
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苗广厚
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Jiangxi Hanshi Biotechnology Co ltd
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Jiangxi Hanshi Biotechnology Co ltd
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Abstract

The invention discloses a tissue sample storage method for oncology department, and belongs to the field of medical instruments. Implemented by a storage device comprising: a bottle body; the sealing device comprises a driving rod, a turning knob, a linkage device and a plurality of turning pieces; the linkage device comprises a turnover rod and a linkage rod. The storage method comprises the following steps: s1, rotating the turning knob to make the turning pieces in the same plane; s2, opening the sealing cover, putting the tissue sample into the infiltration chamber, and covering the sealing cover; s3, inverting the bottle body, opening the injection port and injecting liquid medicine for treating the tissue sample; s4, rotating the turning knob to make the containing chamber and the infiltration chamber communicated, and making the liquid medicine enter the infiltration chamber; s5, repeating the step S1. The invention can reduce the volatilization amount, the problem of liquid medicine volatilization does not exist in the whole taking and placing process, and meanwhile, the bottle body can be repeatedly used, thereby reducing the problems of higher cost and environmental pollution caused by the disposable bottle body while reducing the harm to the human body.

Description

Tissue sample storage method for oncology department
Technical Field
The invention relates to the field of medical instruments, in particular to a tissue sample storage method for oncology.
Background
Endoscopic procedures, including bronchoscopy, gastroscopy, enteroscopy, and the like, are commonly used as an access method by modern clinicians. The clinician observes the body cavity structure under the guidance of the built-in endoscope, when the suspicious focus is met, a plurality of small tissues are directly taken under the endoscope and sent to a pathology department for detection so as to determine the type of the lesion and further determine a treatment scheme.
During the storage and transportation process, the tissue specimen needs to be preserved to prevent the tissue from being polluted or denatured. Formalin in the existing tissue specimen tissue storage is still the first choice liquid medicine for tissue fixation, but formalin is a reducing agent, contains 4% of formaldehyde, is extremely volatile, and has carcinogenicity in the literature report. When fixing the tissue specimen after operation, the medical staff needs to put the specimen into the pathological specimen inspection bottle filled with formalin. Doctor protection is found to be problematic in clinical work when tissue specimens are fixed: that is every time the doctor puts into the specimen and send and examine the bottle the volatile gas of formalin will be inhaled, causes the injury to the health. If human skin is directly contacted with formalin, allergic reaction, dermatitis or eczema may be caused, and such phenomena are often caused especially for people who need to be contacted with formalin for a long time in work. Formaldehyde is very volatile, has strong irritation and injury to eyes, and can be used for treating eye diseases if formalin solution is contacted with eyes carelessly. If the medicine is inhaled carelessly, the medicine can stimulate mucous membrane tissues of mouth, nose and respiratory tract, pain and cough are caused slightly, the respiratory tract is inflamed seriously, and even pulmonary edema is caused. In recent years, occupational protection is more and more emphasized, but the conventional tissue specimen inspection bottle is difficult to protect because a tissue specimen is soaked in formalin and then taken out from a liquid medicine during inspection, and the liquid medicine directly contacts air and a human body in the process of access.
Disclosure of Invention
The invention provides a tissue sample storage method for oncology, which can solve the problems that medicine volatilization is easy to affect human health and tissue samples are inconvenient to store in the sample storage process in the prior art.
A method for storing tissue samples for oncology, the method being implemented by a storage device comprising:
the bottle body is in a hollow cylindrical shape, a supporting column is arranged on the bottom wall of the bottle body, the bottle body is provided with a sealing cover, the bottle body is provided with an injection port, and a plug body for plugging the injection port is arranged at the injection port;
the sealing device comprises a driving rod, an overturning knob, a linkage device and a plurality of overturning sheets, wherein the linkage device corresponds to the overturning sheets one by one, the cross section of the supporting column is polygonal, the number of the overturning sheets corresponds to the number of the sides of the polygon, the overturning sheets are fan-shaped, the small ends of the overturning sheets coincide with the side lines of the polygon, the large ends of the overturning sheets are matched with the shape of the inner wall of the bottle body, the overturning sheets are in dynamic sealing connection with the supporting column and the bottle body, the small ends of the overturning sheets are rotatably arranged on the supporting column, the overturning sheets are uniformly arranged on the periphery of the supporting column in the circumferential direction, when the overturning sheets are all positioned on the same plane, the inner cavity of the bottle body is divided into a containing chamber and an infiltration chamber, and the infiltration chamber is positioned above the containing chamber;
The linkage device comprises an overturning rod and a linkage rod, one end of the overturning rod is connected to the overturning sheet in a driving mode, the other end of the overturning rod is hinged to one end of the linkage rod, and the other end of the linkage rod is hinged to the end portion, far away from the overturning sheet, of the adjacent overturning rod;
the driving rod is rotatably arranged on the side wall of the bottle body, one end of the driving rod is connected to any one overturning rod in a driving mode, the other end of the driving rod is connected to the overturning knob in a driving mode, and the overturning knob is located on the outer side of the bottle body;
the turnover sheet at least has a first working state and a second working state:
when the bottle is in a first working state, the turnover sheets are positioned on the same plane, the inner cavity of the bottle body is divided into a containing chamber and an infiltration chamber, and the turnover sheets are connected in a sealing way in pairs;
when the turnover device is in a second working state, the turnover pieces are arranged in parallel, and a gap is formed between every two adjacent turnover pieces;
the storage method comprises the following steps:
s1, rotating a turning knob to enable the driving rod to drive the turning rod to rotate, enabling the turning rod to drive the turning pieces to rotate, enabling the turning pieces to be located on the same plane, dividing the inner cavity of the bottle body into two containing chambers and an infiltration chamber which are sealed mutually, and enabling the infiltration chamber to be used for storing tissue samples and/or liquid medicine;
S2, opening the sealing cover, putting the tissue sample into the infiltration chamber, and covering the sealing cover;
s3, inverting the bottle body, opening the injection port, injecting liquid medicine for treating the tissue sample, and sealing the injection port through the plug body;
s4, rotating a turning knob to enable the driving rod to drive the turning rod to rotate reversely, and enabling the turning rod to drive the turning pieces to rotate, so that a gap is formed between every two turning pieces, the containing chamber and the infiltration chamber are communicated, and liquid medicine enters the infiltration chamber;
s5, repeating the step S1 to seal the containing chamber and the infiltration chamber;
and S6, rightly placing the bottle body.
Preferably, two opposite side edges of the turning pieces are provided with inclined planes, the inclined planes are coated with magnetic attraction coatings, and the magnetic attraction coatings attract each other when the two adjacent turning pieces are positioned on the same plane.
Preferably, the storage device further comprises a lifting device, which comprises a filter screen cover, a driving screw rod, a power magnetic ring and a lifting magnetic ring, wherein the driving screw rod is rotatably arranged on the outer side wall of the bottle body, the power magnetic ring and the lifting magnetic ring are positioned on two sides of the side wall of the bottle body, a limiting groove is formed in the outer side wall of the bottle body, and a limiting part is arranged on the power magnetic ring; the limiting part is matched with the limiting groove and used for limiting the rotation of the power magnetic ring; the limiting part is provided with a threaded hole matched with the driving screw rod, and the driving screw rod drives the power magnetic ring to move up and down when rotating; the lifting magnetic ring is fixedly arranged on the filter screen cover and corresponds to the power magnetic ring, the power magnetic ring and the lifting magnetic ring are mutually attracted, and when the power magnetic ring is lifted, the lifting magnetic ring is driven to drive the filter screen cover to move up and down;
The S2 further includes:
s21, opening the sealing cover, and placing the tissue sample into a filter screen cover;
s22, rotating the driving screw to enable the driving screw to drive the power magnetic ring to move downwards, and the power magnetic ring drives the lifting magnetic ring to move downwards so as to drive the filter screen cover to move downwards;
and S23, covering the seal cover.
Preferably, the sealing cover comprises an upper sliding disc, a lower sliding disc, a plurality of sliding blocks and stop blocks which correspond to the sliding blocks one by one;
the upper sliding disc is circular, a first central hole is formed in the center of the upper sliding disc, first sliding grooves are uniformly formed in the upper sliding disc along the circumferential direction of the center, the track of each first sliding groove is arc-shaped and is arranged in an inclined mode overall towards one side, edge covering is arranged on the outer periphery of the upper sliding disc in an extending mode towards one side, and the edge covering is connected with the bottle body in a dynamic sealing mode;
the lower sliding disc is circular, a second central hole is formed in the center of the lower sliding disc, second sliding grooves are uniformly formed in the lower sliding disc along the circumferential direction of the center, the track of each second sliding groove is linear and is obliquely arranged on one side opposite to the corresponding first sliding groove, the surrounding side of the lower sliding disc is wrapped by the wrapping edge, and the lower sliding disc is fixedly connected to the bottle body;
The sliding blocks are of an arc-shaped triangular structure at one side, the sliding blocks are uniformly arranged along the central circumference of the lower sliding disc, the sliding blocks are abutted in pairs to form an annular structure, the sliding blocks are positioned between the upper sliding disc and the lower sliding disc, connecting holes are formed in the sliding blocks, the first sliding grooves, the second sliding grooves, the sliding blocks and the stop blocks are in one-to-one correspondence, the stop blocks penetrate through the first sliding grooves and are rotatably connected to the connecting holes, the stop blocks are slidably arranged in the first sliding grooves, and limit sliding blocks are arranged on the side surfaces, facing the lower sliding disc, of the sliding blocks and are slidably arranged in the second sliding grooves; the sliding block is connected with the upper sliding disc and the lower sliding disc in a sliding and sealing manner;
when the upper sliding disc rotates, the sliding blocks are driven to approach or move away from each other;
the driving screw is provided with a driving gear, the peripheral side wall of the upper sliding disc is provided with tooth grooves matched with the driving gear, and the driving gear drives the upper sliding disc to rotate when rotating;
the S21 further includes:
s211, rotating the driving screw to enable the driving screw to drive the power magnetic ring to move upwards, and enabling the power magnetic ring to drive the lifting magnetic ring to move upwards so as to drive the filter screen cover to move upwards; meanwhile, the driving screw drives the driving gear to rotate, the driving gear drives the upper sliding disc to rotate, and the upper sliding disc drives the sliding blocks to move, so that a gap is formed between the sliding blocks;
S212, placing the tissue sample into a filter screen cover;
s213, reversely rotating the driving screw to enable the driving screw to drive the power magnetic ring to move downwards, and the power magnetic ring drives the lifting magnetic ring to move downwards so as to drive the filter screen cover to move downwards; and meanwhile, the driving screw drives the driving gear to rotate reversely, the driving gear drives the upper sliding plate to rotate reversely, and the upper sliding plate drives the sliding blocks to move reversely, so that the sliding blocks are closed oppositely.
Preferably, the two tangent sides of the sliding blocks are coated with magnetic absorption layers for enabling the sliding blocks to attract each other.
The invention provides a tissue sample storage method for oncology, which is characterized in that liquid medicine is injected through a small injection port, the injection port can be designed to be small, volatilization amount can be reduced by means of conventional laboratory tools such as an injector and the like, an overturning sheet divides a storage chamber, the tissue sample is placed from the upper side of a bottle body without causing volatilization of the medicine, after the tissue sample is placed, the bottle body is sealed and blocked by a sealing cover, an overturning knob is rotated and inverted, and then the rotating knob is rotated reversely to lead the overturning sheet to be blocked, so that the tissue sample can be in liquid medicine soaking; when taking a tissue sample, the operation is reversed. The whole taking and placing process has no problem of liquid medicine volatilization, the operation process is simple and convenient, and the lifting of the filter screen cover and the synchronous opening and closing of the sealing cover can be realized through one-step operation.
Drawings
FIG. 1 is a schematic structural diagram of a method for storing a tissue sample for oncology provided in the present invention;
FIG. 2 is a top view of FIG. 1;
FIG. 3 is a sectional view taken along line A-A of FIG. 2;
FIG. 4 is an enlarged view of a portion B of FIG. 3;
FIG. 5 is a front view of FIG. 2;
FIG. 6 is a cross-sectional view taken at C-C of FIG. 5;
FIG. 7 is a first schematic structural view of the closure device;
FIG. 8 is a second schematic structural view of the closure device;
FIG. 9 is a schematic view of the closure;
FIG. 10 is an exploded view one of FIG. 9;
FIG. 11 is an exploded view II of FIG. 9;
FIG. 12 is a first schematic structural view of the upper pulley;
FIG. 13 is a second schematic structural view of the upper slide plate;
FIG. 14 is a front view of FIG. 12;
FIG. 15 is a first schematic structural diagram of a slider;
FIG. 16 is a second schematic structural diagram of a slider;
FIG. 17 is a first schematic structural view of the lower sliding tray;
fig. 18 is a structural schematic diagram of the lower sliding plate.
Description of reference numerals:
10. a protective cover; 11. an upper sliding plate; 111. a first central aperture; 112. a first chute; 113. edge covering; 12. a slider; 121. connecting holes; 122. a limiting slide block; 13. a stopper; 14. a lower sliding plate; 141. a second central aperture; 142. a second chute; 20. a bottle body; 21. a drive section; 22. a support pillar; 23. an injection port; 30. a drive screw; 31. a drive gear; 32. a drive knob; 40. a filter screen cover; 41. a power magnetic ring; 411. a limiting part; 42. lifting the magnetic ring; 50. turning over the sheet; 51. turning over the knob; 52. a turning rod; 53. a linkage rod.
Detailed Description
One embodiment of the present invention will be described in detail below with reference to the accompanying drawings, but it should be understood that the scope of the invention is not limited to the embodiment.
The first embodiment is as follows:
as shown in fig. 1 to 8, a method for storing a tissue sample for oncology provided by an embodiment of the invention is implemented by a storage device, the device comprising:
the bottle body 20 is in a hollow cylindrical shape, a support column 22 is arranged on the bottom wall of the bottle body 20, the bottle body 20 is provided with a sealing cover 10 for sealing the cavity of the bottle body 20, the bottom of the bottle body 20 is provided with an injection port 23, and a plug body for sealing the injection port 23 is arranged at the position of the injection port 23;
a sealing device, which comprises a driving rod, a turning rod 52, a turning knob 51, a linkage device and a plurality of turning sheets 50, wherein the linkage device is in one-to-one correspondence with the turning sheets 50, the cross section of the supporting column 22 is polygonal, as shown in fig. 6, the number of the turning sheets 50 is corresponding to the number of the sides of the polygon, the turning sheets 50 are fan-shaped, the small ends of the turning sheets 50 are coincident with the side lines of the polygon, and the large ends are adapted to the shape of the inner wall of the bottle body 20, wherein the small ends refer to the end parts folded inwards in the fan shape, the large ends refer to the end parts with the opposite sides and the larger radian, the small ends of the turning sheets 50 are rotatably arranged on the supporting column 22, when the turning sheets 50 are turned, the small ends are flatly attached to the side surfaces of the supporting column 22 to keep a sealing state, the plurality of turning sheets 50 are circumferentially and uniformly arranged on the peripheral sides of the supporting column 22, and when the plurality of turning sheets 50 are on the same plane, the inner cavity of the bottle body 20 is divided into a containing chamber and a soaking chamber, the infiltration chamber is positioned above the containing chamber;
As shown in fig. 7 and 8, the linkage device comprises an overturning rod 52 and a linkage rod 53, one end of the overturning rod 52 is connected to the overturning sheet 50 in a driving manner, the other end of the overturning rod is hinged to one end of the linkage rod 53, and the other end of the linkage rod 53 is hinged to the end of the adjacent overturning rod 52 far away from the overturning sheet 50; wherein, the turning rod 52 is arc-shaped so as to enable a plurality of linkages to be wound around the bottle body 20 for connecting and driving the turning sheet 50, the structure shown in fig. 7 and 8 is only convenient for expressing the structure, not the real projection state, and the turning rod 52 is actually arc-shaped.
The driving rod is rotatably arranged on the side wall of the bottle body 20, one end of the driving rod is connected to any one turning rod 52 in a driving way, the other end of the driving rod is connected to the turning knob 51 in a driving way, and the turning knob 51 is positioned on the outer side of the bottle body 20;
the turning sheet 50 has at least a first working condition and a second working condition:
when the bottle is in the first working state, the plurality of turnover pieces 50 are positioned on the same plane, the inner cavity of the bottle body 20 is divided into two chambers, and the turnover pieces 50 are connected in a sealing way two by two;
when the device is in the second working state, the plurality of turning pieces 50 are arranged in parallel and a gap is formed between two adjacent turning pieces 50.
The storage method comprises the following steps:
s1, rotating the turning knob 51 to make the driving rod drive the turning rod 52 to rotate, the turning rod 52 drives the turning sheet 50 to rotate, so that the turning sheets 50 are positioned on the same plane, and the inner cavity of the bottle body is divided into two mutually sealed containing chambers and an infiltration chamber, and the infiltration chamber is used for storing tissue samples and/or liquid medicine;
S2, opening the sealing cover, putting the tissue sample into the infiltration chamber, and covering the sealing cover;
s3, inverting the bottle body, opening the injection port, injecting the liquid medicine for processing the tissue sample, and sealing the injection port through the plug body;
s4, rotating the turning knob 51 to make the driving rod drive the turning rod 52 to rotate reversely, the turning rod 52 driving the turning sheet 50 to rotate, making a gap formed between every two of the turning sheets 50, making the containing chamber and the infiltration chamber through, and making the liquid medicine enter the infiltration chamber;
s5, repeating the step S1 to seal the containing chamber and the infiltration chamber;
s6, rightly placing the bottle body.
When the bottle is used, the turning knob 51 is firstly rotated, the turning rod 52 drives the linkage rod 53 and further drives the turning sheet 50 to rotate to be in the same plane, the inner cavity of the bottle body 20 is divided into two cavities which are independent and sealed, liquid medicine is added through the injection opening 23, and then the injection opening 23 is sealed by the plug body. The sealing cover 10 is opened, the tissue sample is placed into the cavity on the upper portion of the turnover pieces 50, the sealing cover 10 is covered, then the turnover knob 51 is rotated reversely, gaps are formed between the turnover pieces 50 in a staggered mode, the bottle body 20 is reversely inverted, the liquid medicine flows into the cavity on the upper portion through the gaps between the turnover pieces 50, the tissue sample is soaked in the liquid medicine, then the turnover knob 51 is rotated reversely again, the turnover pieces 50 are located on the same plane, sealing is achieved, the liquid medicine cannot return to the cavity on the lower portion, and the tissue sample can be kept soaked in the liquid medicine. When taking, the turning knob 51 is rotated reversely again to make the liquid medicine flow into the lower cavity through the gap, and then the turning knob 51 is rotated to make the turning piece 50 be in the first working state, at this moment, the tissue sample is no longer in the liquid medicine, the end cover can be opened to take the tissue sample, and the liquid medicine can be discharged through the inversion mode or directly from the injection port 23. Whole process injects the liquid medicine from filling opening 23 through sealing device, when depositing and taking, the liquid medicine all can not contact with the air, does not have the volatile condition of liquid medicine, and bottle 20 repeatedly usable of recycling.
Further, in order to prevent that upset piece 50 upset is not in place or the improper upset under self action of gravity, an inclined plane has all been seted up to two relative sides of upset piece 50, all coats on the inclined plane and has inhaled the coating magnetically, and when two adjacent upset pieces 50 were in the coplanar, the coating attracted magnetically mutually to guarantee to exert under certain external force condition, just can make upset piece 50 be in second operating condition, improve the security of using.
The second embodiment:
in the first embodiment, since some tissue samples are larger and some tissue samples are smaller, in order to improve the storage versatility, and the tissue samples can be conveniently taken when the cavity is deeper, the present embodiment further includes a lifting device, which includes a filter screen cover 40, a driving screw 30, a power magnetic ring 41 and a lifting magnetic ring 42, the upper end of the driving screw 30 is provided with a driving knob 32 for convenient rotation, the driving screw 30 is rotatably disposed on the outer side wall of the bottle body 20, the power magnetic ring 41 and the lifting magnetic ring 42 are located on both sides of the side wall of the bottle body 20, the outer side wall of the bottle body 20 is provided with a limiting groove, and the power magnetic ring 41 is provided with a limiting portion 411; the limiting part 411 is matched with the limiting groove and used for limiting the rotation of the power magnetic ring 41; a threaded hole matched with the driving screw 30 is formed in the limiting part 411, and when the driving screw 30 rotates, the power magnetic ring 41 is driven to move up and down; the lifting magnetic ring 42 is fixedly disposed on the filter screen cover 40 and corresponds to the power magnetic ring 41, the power magnetic ring 41 and the lifting magnetic ring 42 attract each other, and when the power magnetic ring 41 is lifted, the lifting magnetic ring 42 is driven to drive the filter screen cover 40 to move up and down.
S2 further includes:
s21, opening the sealing cover, and placing the tissue sample into a filter screen cover;
s22, rotating the driving screw 30 to make the driving screw 30 drive the power magnetic ring 41 to move downwards, and the power magnetic ring 41 drives the lifting magnetic ring 42 to move downwards to drive the filter screen cover 40 to move downwards;
and S23, covering a seal cover.
It should be noted that the bottle body 20 may be configured as a double-layer structure, and the outer layer of the bottle body 20 protrudes outward to form a driving portion 21, so that the limiting portion 411 is covered in the bottle body 20, thereby improving the appearance.
The power magnetic ring 41 is matched with the lifting magnetic ring 42, so that the power magnetic ring 41 can be synchronously lifted without being directly contacted with the power magnetic ring 41, and the sealing problem in the direct contact process is avoided.
The driving screw 30 is rotated, the power magnetic ring 41 cannot rotate under the action of the limiting portion 411, the driving screw 30 is matched with the threaded hole, the driving screw 30 drives the power magnetic ring 41 to lift when rotating, so that the lifting magnetic ring 42 is driven to lift, and the lifting magnetic ring 42 drives the filter screen cover 40 to lift synchronously. When the tissue sample is stored, the tissue sample is placed in the filter screen cover 40, and when the tissue sample is taken, the tissue sample is driven to rise through the filter screen cover 40, so that the tissue sample is convenient to take. When depositing great tissue sample, great headspace can improve the suitability of depositing, and to less tissue sample, although headspace is darker, because screen panel 40 liftable, consequently also can not increase the degree of difficulty of taking.
Example three:
in the first or second embodiment, the end cap needs to be opened and closed in separate operation steps, the opening and closing of the end cap and the lifting and lowering of the screen cover 40 cannot be synchronized, and the operation needs to be performed in two steps, so that the ease of use is deteriorated. More noteworthy, because in order to be able to store a larger tissue sample, the depth of the inner cavity of the bottle body 20 is generally designed to be larger, and when the filter screen cover 40 is located at a lower position, directly placing the tissue sample can lead to the tissue sample to impact with the filter screen cover 40 due to the gravity in the placing process, which leads to the problems of tissue deformation and the like, therefore, the filter screen cover 40 needs to be raised first during storage, and then lowered to the lower position after placement, which leads to very complicated use.
In the present embodiment, cover 10 includes upper slide plate 11, lower slide plate 14, a plurality of slide blocks 12, and stoppers 13 corresponding to slide blocks 12 one to one;
the upper sliding disc 11 is circular, a first central hole 11 is formed in the center of the upper sliding disc 11, first sliding grooves 112 are uniformly formed in the upper sliding disc 11 along the circumferential direction of the center, the track of each first sliding groove 112 is arc-shaped and is arranged to incline towards one side in general, edge covering 113 is arranged on one side of the outer periphery of the upper sliding disc 11 in an extending mode, and the edge covering 113 is connected with the bottle body 20 in a sliding and sealing mode;
The lower sliding plate 14 is circular, a second central hole 141 is formed in the center of the lower sliding plate 14, second sliding grooves 142 are uniformly formed in the upper edge of the lower sliding plate 14 along the circumferential direction of the center, the track of each second sliding groove 142 is linear and is obliquely arranged on one side opposite to the corresponding first sliding groove 112, the wrapping edges 113 wrap the circumferential side of the lower sliding plate 14, and the lower sliding plate 14 is fixedly connected to the bottle body 20;
sliding block 12 is an arc-shaped triangular structure on one side, a plurality of sliding blocks 12 are uniformly arranged along the central circumference of lower sliding disc 14, a plurality of sliding blocks 12 are abutted in pairs to form an annular structure, sliding block 12 is positioned between upper sliding disc 11 and lower sliding disc 14, sliding block 12 is provided with connecting hole 121, first sliding groove 112, second sliding groove 142, sliding block 12 and stop block 13 are in one-to-one correspondence, stop block 13 passes through first sliding groove 112 and is rotatably connected to connecting hole 121, stop block 13 is slidably arranged in first sliding groove 112, a limit slider 122 is arranged on the side of sliding block 12 facing lower sliding disc 14, and limit slider 122 is slidably arranged in second sliding groove 142; sliding block 12 is connected with upper sliding disc 11 and lower sliding disc 14 in a sliding and sealing manner;
when upper sliding disc 11 rotates, sliding blocks 12 are driven to move close to or away from each other;
the driving screw 30 is provided with a driving gear 31, the peripheral side wall of the upper sliding tray 11 is provided with tooth grooves matched with the driving gear 31, and the driving gear 31 drives the upper sliding tray 11 to rotate when rotating.
S21 further includes:
s211, rotating the driving screw 30 to enable the driving screw 30 to drive the power magnetic ring 41 to move upwards, and enabling the power magnetic ring 41 to drive the lifting magnetic ring 42 to move upwards so as to drive the filter screen cover 40 to move upwards; simultaneously, the driving screw 30 drives the driving gear 31 to rotate, the driving gear 31 drives the upper sliding disc 11 to rotate, the upper sliding disc 11 drives the sliding blocks 12 to move, and a gap is formed between the sliding blocks 12;
s212, placing the tissue sample into a filter screen cover 40;
s213, reversely rotating the driving screw 30 to make the driving screw 30 drive the power magnetic ring 41 to move down, and the power magnetic ring 41 drives the lifting magnetic ring 42 to move down to further drive the filter screen cover 40 to move down; meanwhile, drive screw 30 drives drive gear 31 to rotate reversely, drive gear 31 drives upper sliding plate 11 to rotate reversely, upper sliding plate 11 drives sliding blocks 12 to move reversely, and sliding blocks 12 are closed oppositely.
During the use, when the tissue sample needs to be taken, drive screw 30 is rotated, drive screw 30 drives drive gear 31 and rotates, drive gear 31 drives upper sliding plate 11 and rotates, when upper sliding plate 11 rotates, stopper 13 is forced to move through first spout 112, stopper 13 drives sliding block 12 and moves, and sliding block 12 slides under the mating reaction of limit stop 13 and second spout 142 again simultaneously, is the specific movement orbit, finally realizes that a plurality of sliding blocks 12 are close to each other or keep away from each other. When the driving screw 30 drives the power magnetic ring 41 to move upwards, the driving gear 31 drives the upper sliding disc 11 to rotate, and drives the plurality of sliding blocks 12 to move away from each other, so that the end cover is in an open state, a taking and placing opening (coinciding with or partially coinciding with the first central hole 111 and/or the second central hole 141) is formed between the plurality of sliding blocks 12, the filter screen cover 40 continuously rises in the process of enlarging the taking and placing opening, and when the taking and placing opening changes to the maximum, the filter screen cover 40 is at the highest position, and at the moment, a tissue sample is taken. During storage, the pick-and-place opening is opened, the filter screen cover 40 is located at the highest position, the tissue sample can be conveniently placed on the filter screen cover 40, then the screw rod 30 is driven to rotate reversely, the pick-and-place opening is reduced, the filter screen cover 40 descends synchronously, and when the pick-and-place opening disappears (the sliding blocks 12 are attached to each other), the filter screen cover 40 is located at the lowest point.
Further, the sides of sliding blocks 12 that are tangent to each other in pairs are coated with a magnetically attracting layer for attracting sliding blocks 12 to each other.
The above disclosure is only for a few specific embodiments of the present invention, however, the present invention is not limited to the above embodiments, and any variations that can be made by those skilled in the art are intended to fall within the scope of the present invention.

Claims (3)

1. A method for storing tissue samples for oncology, the method being implemented by a storage device comprising:
the bottle body is in a hollow cylindrical shape, a supporting column is arranged on the bottom wall of the bottle body, the bottle body is provided with a sealing cover, the bottle body is provided with an injection port, and a plug body for plugging the injection port is arranged at the injection port;
the sealing device comprises a driving rod, an overturning knob, a linkage device and a plurality of overturning sheets, wherein the linkage device corresponds to the overturning sheets one by one, the cross section of the supporting column is polygonal, the number of the overturning sheets corresponds to the number of the sides of the polygon, the overturning sheets are fan-shaped, the small ends of the overturning sheets coincide with the side lines of the polygon, the large ends of the overturning sheets are matched with the shape of the inner wall of the bottle body, the overturning sheets are in dynamic sealing connection with the supporting column and the bottle body, the small ends of the overturning sheets are rotatably arranged on the supporting column, the overturning sheets are uniformly arranged on the periphery of the supporting column in the circumferential direction, when the overturning sheets are all positioned on the same plane, the inner cavity of the bottle body is divided into a containing chamber and an infiltration chamber, and the infiltration chamber is positioned above the containing chamber;
The linkage device comprises an overturning rod and a linkage rod, one end of the overturning rod is connected to the overturning sheet in a driving mode, the other end of the overturning rod is hinged to one end of the linkage rod, and the other end of the linkage rod is hinged to the end, far away from the overturning sheet, of the adjacent overturning rod;
the driving rod is rotatably arranged on the side wall of the bottle body, one end of the driving rod is connected to any one overturning rod in a driving mode, the other end of the driving rod is connected to the overturning knob in a driving mode, and the overturning knob is located on the outer side of the bottle body;
the turnover sheet at least has a first working state and a second working state:
when the bottle is in a first working state, the turnover sheets are positioned on the same plane, the inner cavity of the bottle body is divided into a containing chamber and an infiltration chamber, and the turnover sheets are connected in a sealing way in pairs;
when the turnover device is in a second working state, the turnover pieces are arranged in parallel, and a gap is formed between every two adjacent turnover pieces;
two opposite side edges of the turnover pieces are respectively provided with an inclined surface, the inclined surfaces are coated with a magnetic attraction coating, and when two adjacent turnover pieces are positioned on the same plane, the magnetic attraction coatings attract each other;
the storage device also comprises a lifting device which comprises a filter screen cover, a driving screw rod, a power magnetic ring and a lifting magnetic ring, wherein the driving screw rod is rotatably arranged on the outer side wall of the bottle body, the power magnetic ring and the lifting magnetic ring are positioned on two sides of the side wall of the bottle body, a limiting groove is formed in the outer side wall of the bottle body, and a limiting part is arranged on the power magnetic ring; the lifting magnetic ring is fixedly arranged on the filter screen cover and corresponds to the power magnetic ring, the power magnetic ring and the lifting magnetic ring are mutually attracted, and when the power magnetic ring is lifted, the lifting magnetic ring is driven to drive the filter screen cover to move up and down; the limiting part is matched with the limiting groove and used for limiting the rotation of the power magnetic ring; the limiting part is provided with a threaded hole matched with the driving screw rod, and the driving screw rod drives the power magnetic ring to move up and down when rotating;
The storage method comprises the following steps:
s1, rotating a turning knob to enable the driving rod to drive the turning rod to rotate, enabling the turning rod to drive the turning pieces to rotate, enabling the turning pieces to be located on the same plane, dividing the inner cavity of the bottle body into two containing chambers and an infiltration chamber which are sealed mutually, and enabling the infiltration chamber to be used for storing tissue samples and/or liquid medicine;
s2, including:
s21, opening the sealing cover, and placing the tissue sample into a filter screen cover;
s22, rotating the driving screw to enable the driving screw to drive the power magnetic ring to move downwards, and the power magnetic ring drives the lifting magnetic ring to move downwards so as to drive the filter screen cover to move downwards;
s23, covering the seal cover;
s3, inverting the bottle body, opening the injection port, injecting liquid medicine for treating the tissue sample, and sealing the injection port through the plug body;
s4, rotating a turning knob to enable the driving rod to drive the turning rod to rotate reversely, and enabling the turning rod to drive the turning pieces to rotate, so that a gap is formed between every two turning pieces, the containing chamber and the infiltration chamber are communicated, and liquid medicine enters the infiltration chamber;
s5, repeating the step S1 to seal the containing chamber and the infiltration chamber;
S6, rightly placing the bottle body.
2. The method as claimed in claim 1, wherein the cover comprises an upper slide plate, a lower slide plate, a plurality of slide blocks and stop blocks corresponding to the slide blocks;
the upper sliding disc is circular, a first central hole is formed in the center of the upper sliding disc, first sliding grooves are uniformly formed in the upper sliding disc along the circumferential direction of the center, the track of each first sliding groove is arc-shaped and is arranged in an inclined mode overall towards one side, edge covering is arranged on the outer periphery of the upper sliding disc in an extending mode towards one side, and the edge covering is connected with the bottle body in a dynamic sealing mode;
the lower sliding disc is circular, a second central hole is formed in the center of the lower sliding disc, second sliding grooves are uniformly formed in the lower sliding disc along the circumferential direction of the center, the track of each second sliding groove is linear and is obliquely arranged on one side opposite to the corresponding first sliding groove, the surrounding side of the lower sliding disc is wrapped by the wrapping edge, and the lower sliding disc is fixedly connected to the bottle body;
the sliding blocks are of an arc-shaped triangular structure at one side, the sliding blocks are uniformly arranged along the central circumference of the lower sliding disc, the sliding blocks are abutted in pairs to form an annular structure, the sliding blocks are positioned between the upper sliding disc and the lower sliding disc, connecting holes are formed in the sliding blocks, the first sliding grooves, the second sliding grooves, the sliding blocks and the stop blocks are in one-to-one correspondence, the stop blocks penetrate through the first sliding grooves and are rotatably connected to the connecting holes, the stop blocks are slidably arranged in the first sliding grooves, and limit sliding blocks are arranged on the side surfaces, facing the lower sliding disc, of the sliding blocks and are slidably arranged in the second sliding grooves; the sliding block is connected with the upper sliding disc and the lower sliding disc in a sliding and sealing manner;
When the upper sliding disc rotates, the sliding blocks are driven to approach or move away from each other;
the driving screw is provided with a driving gear, the peripheral side wall of the upper sliding disc is provided with tooth grooves matched with the driving gear, and the driving gear drives the upper sliding disc to rotate when rotating;
the S21 further includes:
s211, rotating the driving screw to enable the driving screw to drive the power magnetic ring to move upwards, and enabling the power magnetic ring to drive the lifting magnetic ring to move upwards so as to drive the filter screen cover to move upwards; meanwhile, the driving screw drives the driving gear to rotate, the driving gear drives the upper sliding disc to rotate, and the upper sliding disc drives the sliding blocks to move, so that a gap is formed between the sliding blocks;
s212, placing the tissue sample into a filter screen cover;
s213, reversely rotating the driving screw to enable the driving screw to drive the power magnetic ring to move downwards, and the power magnetic ring drives the lifting magnetic ring to move downwards so as to drive the filter screen cover to move downwards; and meanwhile, the driving screw drives the driving gear to rotate reversely, the driving gear drives the upper sliding plate to rotate reversely, and the upper sliding plate drives the sliding blocks to move reversely, so that the sliding blocks are closed oppositely.
3. The method as claimed in claim 2, wherein the sliding blocks are coated with magnetic attraction layers on the tangent sides of the sliding blocks for attracting the sliding blocks to each other.
CN202011517471.1A 2020-12-21 2020-12-21 Tissue sample storage method for oncology department Active CN112674072B (en)

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