CN111643128A - Prostate sampling mechanism and sampling specimen box - Google Patents
Prostate sampling mechanism and sampling specimen box Download PDFInfo
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- CN111643128A CN111643128A CN202010672626.2A CN202010672626A CN111643128A CN 111643128 A CN111643128 A CN 111643128A CN 202010672626 A CN202010672626 A CN 202010672626A CN 111643128 A CN111643128 A CN 111643128A
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- 238000005070 sampling Methods 0.000 title claims abstract description 146
- 210000002307 prostate Anatomy 0.000 title claims abstract description 43
- 210000001519 tissue Anatomy 0.000 claims abstract description 65
- 238000003825 pressing Methods 0.000 claims abstract description 36
- 239000012528 membrane Substances 0.000 claims abstract description 25
- 239000007788 liquid Substances 0.000 claims description 20
- 238000002791 soaking Methods 0.000 claims description 20
- 238000007789 sealing Methods 0.000 claims description 15
- 238000009461 vacuum packaging Methods 0.000 claims description 5
- 238000005538 encapsulation Methods 0.000 claims description 3
- 239000012780 transparent material Substances 0.000 claims description 3
- 239000000243 solution Substances 0.000 description 52
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 11
- 238000000034 method Methods 0.000 description 9
- 238000001514 detection method Methods 0.000 description 7
- 238000001574 biopsy Methods 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 210000004907 gland Anatomy 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 210000000664 rectum Anatomy 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 241001070941 Castanea Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 206010060862 Prostate cancer Diseases 0.000 description 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 210000004995 male reproductive system Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0241—Pointed or sharp biopsy instruments for prostate
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B2010/009—Various features of diagnostic instruments
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
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- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a prostate sampling mechanism and a sampling specimen box, wherein the prostate sampling mechanism comprises a bottle body for containing a soak solution, the top end of the bottle body is hermetically connected with a pressing part, and the bottom end of the pressing part is provided with a soak solution containing cavity and a hollow tube which are respectively positioned in the bottle body; the side wall of the hollow pipe is connected with a flexible sampling pad; the middle part of pressing the splenium runs through and sets up the connecting hole that is linked together with soak splendid attire cavity, and the top of pressing the splenium is upwards protruding to be provided with elasticity involucra, and the bottom of elasticity involucra is connected and is provided with promotion portion. When the sampling needle is used for sampling the sample tissue, the sample tissue can be attached to the flexible sampling pad only by pressing the flexible sampling pad without swinging the needle head of the sampling needle, and then the elastic membrane is pressed to drive the pushing part to push the soak solution in the soak solution containing cavity out of the bottle body, so that the soak solution immerses and stores the flexible sampling pad and the sample tissue on the flexible sampling pad, and the soak solution cannot volatilize to the atmosphere.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a prostate sampling mechanism and a sampling specimen box.
Background
The prostate gland is an accessory gland of the male reproductive system, is an unpaired parenchymal gland, is located between the bladder and the urogenital diaphragm, surrounds the root of the urethra, and is a chestnut with a shape and a size similar to a little flat. The upper end is wide, the lower end is sharp and thin, the back of the body is flat and close to the rectum, and the body can be touched by digital examination of the rectum.
The prostate aspiration biopsy is the final standard and the best diagnosis method for diagnosing prostate cancer at present stage, and is mostly the system 12 needle aspiration biopsy and 13 needle aspiration biopsy. Chinese utility model patent with patent publication No. CN206714776U discloses a prostate puncture specimen-box and specimen-box, though the device has solved the sample and has put into the thief hole and take out inconvenient problem from the thief hole, still has following defect:
1) the sample needle syringe needle still needs to swing the sample needle syringe needle after the sample of puncturing, just can get rid of the pipe body with the sample tissue, and the people hand is in the time of swinging the sample needle syringe needle, and it is external to get rid of the pipe body with the sample tissue very easily, causes the pollution to the surrounding environment. Or the sampling needle head slides along the tube wall, so that the sample tissue falls into the tube body, but the sample tissue is partially adhered to the wall side of the tube body, and the adhered sample tissue not only affects the measurement result, but also needs to be cleaned before next sampling.
Or the sample tissue on the needle head of the sampling needle needs to be scratched into the tube body by external equipment, so that the operation time is long, and the operation progress is influenced.
2) When the needle head of the sampling needle is thrown into sample tissues, formalin is placed in the tube body; or after the needle head of the sampling needle is thrown into the sample tissue, the formalin is poured into the tube body. The body must be for the state of opening when can't adopt which kind of mode when putting into sample tissue, can lead to the formalin to leak like this, volatilizees to in the air on every side, causes the influence to medical personnel's health.
Disclosure of Invention
The invention provides a prostate sampling mechanism and a sampling specimen box, aiming at solving the problems that the existing sampling device is very difficult to sample and collect sample tissues and soaking liquid is easy to volatilize to influence the health of medical care personnel, so that the sampling and collection of the sample tissues are very convenient and fast, and the possibility of volatilization of the soaking liquid is avoided.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows.
The prostate sampling mechanism comprises a bottle body for containing soak solution, wherein the top end of the bottle body is hermetically connected with a pressing part, and the bottom end of the pressing part is provided with a soak solution containing cavity which is respectively positioned in the bottle body and used for vacuum packaging of the soak solution and a hollow pipe which is communicated with the bottom end of the soak solution containing cavity and used for conveying the soak solution in the soak solution containing cavity into the bottle body; the side wall of the hollow tube is connected with a flexible sampling pad which can form an included angle under the action of external force and is unfolded under the action of no external force so as to facilitate the sample tissue on the needle head of the sampling needle to be attached to the upper side; the middle part of pressing the splenium runs through and sets up the connecting hole that is linked together with soak solution splendid attire cavity, and the top of pressing the splenium is upwards protruding to be provided with the shutoff in the connecting hole top, is used for the elastic membrane that the staff pressed, and the bottom connection of elastic membrane is provided with the promotion portion that the slip encapsulation set up in soak solution splendid attire cavity, is used for realizing that the soak solution in soak solution splendid attire cavity extrudes from the hollow tube when the staff pushes down elastic membrane.
According to the technical scheme, the pressing part comprises a rotary cover in sealing connection with the top end of the bottle body and a cock in threaded connection with the rotary cover, the connecting hole penetrates through the rotary cover and the cock, and the elastic membrane is arranged on the cock; the rotary cover is provided with a first vent hole communicated with the soaking liquid containing cavity, the rotary plug is provided with a second vent hole corresponding to the first vent hole when rotating to the position, and an air inlet hole is formed when the first vent hole corresponds to the second vent hole; the rotary cover is also provided with a micro exhaust hole, one end of the micro exhaust hole is communicated with the inside of the bottle body, and the other end of the micro exhaust hole is communicated with the atmosphere.
Further optimize technical scheme, the bottom of hollow tube can be dismantled to connect and be provided with the netted strainer that is used for carrying out the collection to the sample tissue that shakes off on the flexible sampling pad.
Further optimize technical scheme, the bottle includes that the components of a whole that can function independently seals the last bottle and lower bottle that set up.
According to the technical scheme, the flexible sampling pad is provided with a plurality of jet holes, the bottom end of the hollow pipe is blocked, a plurality of connecting pipes used for outputting soaking liquid to the jet holes so as to spray the soaking liquid out of the jet holes and further punching sample tissues on the flexible sampling pad are communicated and arranged between the hollow pipe and the jet holes, and the connecting pipes are embedded in the flexible sampling pad.
Further optimize technical scheme, be provided with the check valve that is used for preventing in the bottle soak backward flow to the soak splendid attire cavity on the hollow tube.
Sample specimen-box, including the box body, seted up a plurality of thief holes on the top face of box body, the splendid attire is provided with prostate sampling mechanism in the thief hole.
According to the technical scheme, a sliding groove is formed in the side wall of the box body, a horizontal sliding plate is arranged in the sliding groove in a sliding mode, and a label position which is opposite to the sampling hole position and is applied to representing the sampling position of the prostate sampling mechanism in the sampling hole is arranged on the sliding plate; the bottom of the sampling hole is made of transparent materials.
According to the technical scheme, the box body comprises an upper box body and a lower box body which are clamped up and down, and the sampling holes are respectively and correspondingly formed in the upper box body and the lower box body; the bottle body includes for the last bottle and the lower bottle of mutual joint between, goes up bottle and last box body interference fit, lower bottle and lower box body interference fit.
Due to the adoption of the technical scheme, the technical progress achieved by the invention is as follows.
When sampling the sample tissue, the invention can attach the sample tissue to the flexible sampling pad only by pressing the flexible sampling pad without swinging the needle head of the sampling needle, and then push the pushing part to push the soak solution in the soak solution containing cavity into the bottle body by pressing the elastic membrane, so that the soak solution can immerse and store the flexible sampling pad and the sample tissue thereon, thereby realizing sampling of the sample tissue.
According to the invention, the pressing part is set to be of a split structure, the first vent hole is formed in the rotary cover, the second vent hole is formed in the cock, the micro vent hole is further formed in the rotary cover, and then the cock is rotated by hands, so that the first vent hole and the second vent hole are in corresponding positions, at the moment, the upper part of the interior of the soaking liquid containing cavity and the interior of the bottle body are respectively communicated with the atmosphere, and further, the hands can press the elastic membrane very conveniently, and the problem that the elastic membrane is difficult to press due to the fact that gas in the bottle body cannot be discharged is solved. After the soak solution is discharged, the cock is rotated again, so that the first vent hole and the second vent hole are staggered, the sealing can be realized, and the smell of the soak solution is prevented from overflowing.
According to the invention, the flexible sampling pad is provided with the plurality of injection holes, the bottom end of the hollow pipe is blocked, and the plurality of connecting pipes are communicated between the hollow pipe and the injection holes, so that the phenomenon that sample tissues on the side wall of the flexible sampling pad cannot be flushed can be avoided.
The bottom end of the hollow pipe is detachably connected with the mesh-shaped strainer, so that sample tissues falling from the flexible sampling pad due to shaking factors are collected, the sample tissues can directly fall into the mesh-shaped strainer, and the problem that the sample tissues fall into the bottle body in the storage process and are inconvenient to take out can be effectively solved.
The upper bottle body is embedded in the upper box body, the upper bottle body is assembled on the lower box body in an interference manner, when the upper box body is opened, the upper bottle body can be directly separated from the lower bottle body, and then the sample tissue can be directly taken out from the lower bottle body filled with the sample tissue for detection.
Drawings
FIG. 1 is a cross-sectional view of the prostate sampling mechanism of example 1;
FIG. 2 is a schematic structural view of a sampling cartridge according to example 3;
FIG. 3 is a schematic view showing the structure of the slide plate of the specimen sampling cassette according to embodiment 3 when it is withdrawn;
FIG. 4 is a schematic view of the mesh strainer of the prostate sampling mechanism of example 2;
FIG. 5 is a cross-sectional view of the prostate sampling mechanism of embodiment 4;
FIG. 6 is a schematic structural view of the prostate sampling mechanism according to embodiment 4;
FIG. 7 is a first schematic view of the screw cap of the prostate sampling mechanism according to embodiment 4;
FIG. 8 is a second schematic structural view of the screw cap of the prostate sampling mechanism of embodiment 4;
FIG. 9 is a schematic view of the structure of a bottle of the prostate sampling mechanism of embodiment 5;
FIG. 10 is a schematic view of the structure of the bottle of the prostate sampling mechanism of embodiment 7;
figure 11 is an exploded view of the sampling cartridge of example 7;
FIG. 12 is a schematic structural view illustrating a connection relationship between the sampling cartridge and the prostate sampling mechanism in the case where the upper case is opened according to embodiment 7;
FIG. 13 is a schematic structural view illustrating a connection relationship between the sampling cartridge and the prostate sampling mechanism in the case where the upper case is not opened according to embodiment 7.
Wherein: 1. the bottle body, 2, a rotary cover, 21, a rotary groove, 22, a first step hole, 23, a second step hole, 25, a first vent hole, 26, a first positioning mark, 3, a soak solution containing cavity, 4, a hollow tube, 5, a one-way valve, 6, a cock, 61, a second vent hole, 62, an elastic membrane, 63, a connecting hole, 64, a second positioning mark, 7, a flexible sampling pad, 9, a spraying hole, 10, a box body, 101, an upper box body, 102, a lower box body, 103, an annular sealing groove, 104, an upper convex sealing ring, 11, a sampling hole, 12, a sliding groove, 121, a rectangular bulge, 13, a sliding plate, 131, a handle, 14, a label position, 15, a micro vent hole, 16, a connecting rod, 17, a piston, 18, a net-shaped strainer, 19, an upper bottle body, 191, an annular bulge, 20, a lower bottle body, 201 and an annular clamping groove.
Detailed Description
The invention will be described in further detail below with reference to the figures and specific examples.
Example 1
A prostate sampling mechanism, as shown in fig. 1, comprises a bottle body 1, a pressing part, a soak solution containing cavity 3, a hollow tube 4, a flexible sampling pad 7, an elastic membrane 62 and a pushing part.
The bottle body 1 is filled with a soaking solution which can be formaldehyde or formalin.
The pressing part is connected to the top end of the bottle body 1 in a sealing manner, the pressing part is of an integral structure, and the pressing part is connected with the bottle body 1 through threads.
The bottom of pressing the portion is provided with soak solution splendid attire cavity 3 and hollow tube 4. The soak solution containing cavity 3 and the hollow tube 4 are respectively positioned in the bottle body 1, the soak solution containing cavity 3 is used for vacuum packaging of the soak solution, and the soak solution containing cavity 3 is cylindrical. Hollow tube 4 intercommunication sets up in soak solution splendid attire cavity 3 bottom, and the bottom of hollow tube 4 is the opening form, because of the setting of soak solution vacuum packaging in soak solution splendid attire cavity 3, and then guarantees that the soak solution in soak solution splendid attire cavity 3 can not appear because of the dead weight phenomenon of flowing out along hollow tube 4 automatically.
The flexible sampling pad 7 is connected and arranged on the side wall of the hollow tube 4 and used for forming an included angle under the action of external force and unfolding when no external force is applied, so that the sample tissue on the needle head of the sampling needle is attached to the upper side. The flexible sampling pad 7 is in the butterfly sheet form when not having the exogenic action, when external force pressed its middle part, and the both ends of flexible sampling pad 7 are buckled to the middle part, and the sample needle can directly be contacted with flexible sampling pad 7, rotates the sample needle, and the sample tissue on the sample needle of being convenient for is attached to flexible sampling pad 7.
The bottom of hollow tube 4 sets up at the end of flexible sample pad 7 along, and hollow tube 4 is arranged in carrying the immersion fluid in the immersion fluid splendid attire cavity to bottle 1.
The middle part of pressing the splenium runs through and is seted up the connecting hole 63 that is linked together with soak splendid attire cavity 3, and the top of pressing the splenium is upwards protruding to be provided with elasticity involucra 62, and elasticity involucra 62 shutoff is in connecting hole 63 top, and the elasticity involucra 62 that sets up is used for the people hand to press.
The bottom end of the elastic membrane 62 is connected with a pushing part, the pushing part is arranged in the soaking liquid containing cavity 3 in a sliding and packaging mode, and the soaking liquid in the soaking liquid containing cavity 3 is extruded out of the hollow pipe 4 when the elastic membrane 62 is pressed down by hands.
The pushing portion includes a connecting rod 16 and a piston 17. Connecting rod 16 fixed connection is in the bottom middle part of elasticity involucra 62, and piston 17 connects the bottom that sets up at connecting rod 16 and the encapsulation setting that slides in soak solution splendid attire cavity 3, and connecting rod 16 and piston 17 that this embodiment set up can guarantee that the staff is when pressing elasticity involucra 62, by elasticity involucra 62 promotion connecting rod 16 and piston 17 lapse, further guarantee that the soak solution in soak solution splendid attire cavity 3 can effectively discharge.
When the soak solution in the bottle body 1 reaches the position of the hollow tube 4, after the elastic membrane 62 is pressed down by hands, the soak solution in the bottle body 1 may flow back to the hollow tube 4 in the elastic recovery process of the elastic membrane 62, and in order to prevent the soak solution in the bottle body 1 from flowing back to the soak solution containing cavity 3, the hollow tube 4 is provided with a one-way valve 5.
The present embodiment performs the sampling process of the sample tissue alone as follows.
The splenium is pressed down to the spiral, places the sampling needle syringe needle that has the sample tissue at flexible sample pad 7 middle part to pressing down flexible sample pad 7, making flexible sample pad 7 form the rugosity, half parcel sampling needle syringe needle presses splenium or sampling needle syringe needle through the rotation, makes the sample tissue on the sampling needle syringe needle all adhere to on flexible sample pad 7.
Then, the pressing part with the sample tissue is hermetically connected to the top end of the bottle body 1, the elastic membrane 62 is pressed downwards, the connecting rod 16 and the piston 17 are pushed downwards by the elastic membrane 62, and the soak solution in the soak solution containing cavity 3 is pushed out into the bottle body through the piston 17, so that the soak solution immerses and preserves the flexible sampling pad 7 and the sample tissue thereon.
When the detection is carried out, the pressing part with the flexible sampling pad 7 can be screwed down, and the sample tissue can be taken out from the flexible sampling pad for detection.
Example 2
Based on embodiment 1, the present embodiment is different from embodiment 1 in that the bottom end of the hollow tube 4 of the prostate sampling mechanism is modified, as shown in fig. 4.
The bottom end of the hollow pipe 4 of the embodiment is detachably connected with a reticular strainer 18. The reticular strainer 18 and the hollow pipe 4 adopt a threaded connection mode, a threaded connection pipe is fixedly connected above the reticular strainer 18, and the threaded connection pipe is in threaded connection with the hollow pipe 4. Threaded connection pipe is hollow tubular structure, and threaded connection pipe's bottom sets up to the opening form, can make the soak flow out.
The netted strainer 18 that sets up in this embodiment is used for moving or rocking the in-process at the bottle, collects the sample tissue that flexible sample pad 7 fell because of rocking the factor, can effectively avoid the sample tissue to fall into the bottle and the inconvenient problem of taking out in the storage process. That is, the sample tissue on the flexible sampling pad 7 breaks away from the flexible sampling pad 7, and can directly fall into the netted strainer 18, so that the sample tissue in the bottle body does not need to be collected again when the detection is carried out, and the sample tissue on the netted strainer 18 and the flexible sampling pad 7 can be directly used as the whole sample tissue to be detected.
Example 3
Based on embodiment 1 or embodiment 2, the present embodiment claims a sampling specimen box, which is shown in fig. 2 to 3, and includes a box body 10, wherein a plurality of sampling holes 11 are formed on a top end surface of the box body 10, and a prostate sampling mechanism is disposed in the sampling holes 11.
The lateral wall of box body 10 has been seted up spout 12, fixedly on the bottom inner wall of spout 12 be provided with a pair of rectangle arch 121 that is parallel to each other, it is provided with horizontally sliding plate 13 to slide in spout 12, a pair of rectangle recess that is parallel to each other and with the protruding 121 slip fit of rectangle is seted up to sliding plate 13's bottom, be provided with label position 14 on sliding plate 13, label position 14 is corresponding with the position of thief hole 11, label position is used for pasting the non-setting adhesive subsides that the sign has the thief position name when using, the person of being convenient for looks over the thief hole and takes over the sample position of splendid attire tissue in the aerial prostate sampling mechanism of. The sample location names may be top left, bottom left, front right, etc.
A handle 131 is connected to the outer side wall of the sliding plate 13, and the handle 131 can pull the sliding plate 13.
The bottom of this embodiment thief hole 11 is the plane, and the bottom of thief hole 11 adopts transparent material, and the bottom of thief hole 11 can adopt printing opacity glass specifically, can directly see the character mark that corresponds in the label position when overlooking thief hole 11, can prevent to get wrong sample.
The present embodiment actually performs the sampling process of the sample tissue as follows.
Firstly, according to the sampling requirement, the label position 14 above the sliding plate 13 is marked with a position mark to ensure that each label position corresponds to a sampling position, and then the sliding plate 13 is inserted into the chute 12.
Then, the prostate sampling mechanism placed in the sampling hole 11 is taken out, and it is ensured that the taken out prostate sampling mechanism corresponds to the position where the subject tissue is sampled from the prostate.
Then, screw down and press the splenium, place the sample needle syringe needle that has the sample tissue at flexible sample pad 7 middle part to press down flexible sample pad 7, make flexible sample pad 7 form the rugosity, half parcel sample needle syringe needle presses splenium or sample needle syringe needle through the rotation, makes the sample tissue on the sample needle syringe needle all adhere to on flexible sample pad 7.
Then, the pressing part with the sample tissue is hermetically connected to the top end of the bottle body 1, the elastic membrane 62 is pressed downwards, the connecting rod 16 and the piston 17 are pushed downwards by the elastic membrane 62, and the soak solution in the soak solution containing cavity 3 is pushed out into the bottle body through the piston 17, so that the soak solution immerses and preserves the flexible sampling pad 7 and the sample tissue thereon.
Finally, the prostate sampling mechanism is returned to the home position.
When sampling the sample tissue, the sample tissue can be attached to the flexible sampling pad 7 only by pressing the flexible sampling pad 7 without swinging the needle head of the sampling needle, and then the soak solution in the soak solution containing cavity 3 is pushed out of the bottle body by pressing the elastic membrane 62 to drive the pushing part, so that the soak solution immerses and stores the flexible sampling pad 7 and the sample tissue thereon, and the sample tissue can be sampled.
When examining, can directly send into the pathology department with the sample specimen-box, will place each prostate sampling mechanism in box body 10 thief hole 11 and take out, open according to the splenium from flexible sample cushion with sample tissue take out the detection can for the sample is very convenient.
Example 4
Based on embodiment 1, the present embodiment is different from embodiment 1 in that the pressing portion of the prostate sampling mechanism is modified as shown in fig. 5 to 8.
This embodiment will press the splenium to set up to components of a whole that can function independently structure, presses the splenium including spiral cover 2 and cock 6, and spiral cover 2 and 6 components of a whole that can function independently settings of cock, cock 6 and spiral cover 2 threaded connection. The screw cap 2 is connected with the top end of the bottle body 1 in a sealing way. The bottom of spiral cover 2 has seted up the spiral groove 21 of annular form, has seted up the internal thread on the inside of spiral groove 21, has seted up the external screw thread on the top outer wall of bottle 1, bottle 1 and spiral groove 21 threaded connection.
The connecting hole is arranged on the rotary cover 2 and the cock 6 in a penetrating way, and the elastic membrane 62 is arranged on the cock 6 in a sealing way.
The spiral cover 2 is provided with a first vent hole 25 communicated with the soak solution containing cavity 3, the cock 6 is provided with a second vent hole 61 corresponding to the first vent hole 25 when rotating to the position, and the first vent hole 25 and the second vent hole 61 form an air inlet hole when corresponding. Specifically, the first ventilation hole 25 is opened in the bottom wall of the first stepped hole 22. The cock 6 is rotated for when first air vent 25 and second air vent 61 do not correspond, can prevent effectively that the soak from volatilizing away, and then can not lead to the fact the influence to medical worker's health, can guarantee simultaneously that the inside soak of soak splendid attire cavity 3 is vacuum packaging's state, guarantees that the soak can not flow out by oneself.
Because the pressing part is hermetically connected with the bottle body 1, the gas in the bottle body 1 can be pushed in the process of the soaking liquid flowing out, so that the phenomenon that the soaking liquid flows out due to the increase of the pressure in the bottle body 1 is caused, and in order to ensure that the soaking liquid in the soaking liquid containing cavity 3 can flow out smoothly when the elastic membrane 62 is pressed by hands, the micro exhaust hole 15 is further formed in the spiral cover 2. One end of the miniature vent hole 15 is communicated with the inside of the bottle body 1, and the other end is communicated with the atmosphere, and because the inner diameter of the miniature vent hole 15 is smaller, the phenomenon that a large amount of soak solution in the bottle body 1 is volatilized to the atmosphere can not occur.
In order to ensure that the medical staff can find whether the screw cap 2 and the cock 6 are rotated in place in time, that is, the first vent hole 25 corresponds to the second vent hole 61, in the embodiment, the first positioning mark 26 is provided on the screw cap 2, the second positioning mark 64 is provided on the cock 6, and when the first positioning mark 26 corresponds to the second positioning mark 64, it indicates that the first vent hole 25 corresponds to the second vent hole 61 at that time.
The embodiment is that the soak solution discharging process inside the soak solution containing cavity 3 actually performs: the cock 6 is rotated by hand to make the positions of the first vent hole 25 and the second vent hole correspond, at this time, the upper part of the interior of the soaking liquid containing cavity 3 and the interior of the bottle body 1 are respectively communicated with the atmosphere, so that the hand can very conveniently press the elastic membrane 62, and the problem that the elastic membrane 62 is difficult to press due to the fact that the gas in the bottle body 1 cannot be discharged is solved. After the soak solution is discharged, the cock 6 is rotated again, so that the first vent hole 25 and the second vent hole are staggered, the sealing can be realized, and the smell of the soak solution is prevented from overflowing.
Example 5
Based on embodiment 1, the difference between this embodiment and embodiment 1 is that the bottle body 1 is configured as a split structure, as shown in fig. 9. The bottle body 1 comprises an upper bottle body 19 and a lower bottle body 20 which are arranged in a split sealing manner, and the upper bottle body is connected with the lower bottle body through threads.
Therefore, when sampling, the upper bottle body and the pressing part do not need to be separated, and only the upper bottle body and the lower bottle body need to be separated, so that the flexible sampling pad 7 can be exposed. After the flexible sampling pad 7 is used for sampling, the upper bottle body 19 and the lower bottle body 20 can be directly connected. When sample tissue detection is carried out to needs, can be directly with lower bottle body screw-off, and then directly to the sample tissue on the flexible sampling pad 7 detect can, perhaps take out sample tissue from the soak solution in lower bottle body and detect for sample, detection are very convenient.
Example 6
The present embodiment is different from embodiment 5 in that the connection relationship between the flexible sampling pad 7 and the hollow tube 4 of the prostate sampling mechanism is improved based on embodiment 5.
Based on the bottle sets up the structure into the components of a whole that can function independently in embodiment 4, the mode that erodees to the bottle is gone on to the sample tissue in this embodiment, the sample tissue on the flexible sample pad 7 is when erodeing, if only through 4 bottom blowout soak solutions of hollow tube, the unable phenomenon of being washed by the erodeed sample tissue on the 7 lateral walls of flexible sample pad may appear, in order to avoid this phenomenon, a plurality of jet orifices 9 have been seted up on the flexible sample pad 7 of this embodiment, the bottom shutoff of hollow tube 4, the intercommunication is provided with a plurality of connecting pipes between hollow tube 4 and the jet orifice 9, the connecting pipe inlays the dress and sets up inside flexible sample pad 7, the connecting pipe is used for exporting the soak to jet orifice 9, in order to realize jet orifice 9 blowout soak, and then the sample tissue on the flexible.
Example 7
Based on embodiments 3 and 6, the present embodiment is different from embodiments 3 and 6 in that the vial body of the prostate sampling mechanism and the cartridge body 10 of the sampling cartridge are modified as shown in fig. 10 to 13.
In this embodiment, the bottle body is divided into a split structure, i.e., the bottle body is divided into an upper bottle body 19 and a lower bottle body 20, the lower bottle body is provided with a circular clamping groove, the bottom end of the upper bottle body is provided with a circular protrusion 191, and the upper bottle body is clamped with the circular clamping groove 201 of the lower bottle body through the circular protrusion 191, as shown in fig. 10.
Meanwhile, in the present embodiment, the case 10 is provided as a separate structure, as shown in fig. 11 to 13. The box body 10 comprises an upper box body 101 and a lower box body 102 which are clamped up and down, sampling holes 11 are respectively and correspondingly formed in the upper box body 101 and the lower box body 102, and the sampling holes in the lower box body 102 are groove-shaped and used for assembling a lower bottle body in an interference fit mode; the upper bottle body is embedded in the sampling hole of the upper box body. The upper box body 101 and the lower box body 102 are buckled with each other, the outer side walls of the upper box body 101 and the lower box body 102 are correspondingly provided with buckles, and the upper box body 101 and the lower box body 102 are firmly clamped through the buckles; after the upper box body and the lower box body are buckled, the upper bottle body and the lower bottle body are assembled.
The chute 12 is opened in the lower case 102. The label positions correspond to the positions of the sampling holes 11 one by one, and the names of the sampling parts (upper left … … and lower left … …) can be pasted by adhesive paper.
In addition, in the present embodiment, an annular protrusion is disposed on the top end surface of the lower box 102, an annular groove fitted with the annular protrusion is disposed on the bottom end surface of the upper box 101, and the lower box 102 and the upper box 101 are clamped by the annular protrusion and the annular groove. An annular sealing groove 103 is formed in the top end face of the annular protrusion, an annular sealing groove is also formed in the corresponding position of the bottom end face of the annular groove of the upper box body 101, and an upper convex sealing ring 104 is embedded in the annular sealing groove, so that liquid leakage in the moving process can be prevented.
This embodiment sets up bottle 1 and box body 10 respectively into detachable form, can guarantee examining time measuring, can directly take off last box body 101, make the splenium of pressing of connecting on the last bottle, soak splendid attire cavity 3, hollow tube 4, flexible sample pad 7, elastic membrane 62 and promotion portion take out, because of lower bottle interference fit is on box body down, go up the bottle and inlay the dress at last box body, when opening last box body, can directly make go up bottle and lower bottle separation, and then can directly take out sample tissue from the lower bottle that inside splendid attire had sample tissue and detect.
Claims (9)
1. Prostate sampling mechanism, bottle (1) including splendid attire soak solution, its characterized in that: the top end of the bottle body (1) is hermetically connected with a pressing part, the bottom end of the pressing part is provided with a soaking liquid containing cavity (3) which is respectively positioned in the bottle body (1) and used for vacuum packaging of soaking liquid, and a hollow pipe (4) which is communicated with the bottom end of the soaking liquid containing cavity (3) and used for conveying the soaking liquid in the soaking liquid containing cavity into the bottle body; the side wall of the hollow tube (4) is connected with a flexible sampling pad (7) which can form an included angle under the action of external force and is unfolded under the action of no external force so as to facilitate the sample tissue on the needle head of the sampling needle to be attached to the upper side; the middle part of pressing the splenium runs through and sets up connecting hole (63) that are linked together with soak solution splendid attire cavity (3), and the top of pressing the splenium is upwards protruding to be provided with the shutoff in connecting hole (63) top, is used for the elasticity involucra (62) that the staff pressed, and the bottom of elasticity involucra (62) is connected and is provided with the promotion portion that the slip encapsulation set up in soak solution splendid attire cavity (3), is used for realizing that the soak solution in soak solution splendid attire cavity (3) is extruded from hollow tube (4) when the staff pushes down elasticity involucra (62).
2. The prostate sampling mechanism of claim 1, wherein: the pressing part comprises a rotary cover (2) connected with the top end of the bottle body (1) in a sealing mode and a cock (6) in threaded connection with the rotary cover (2), a connecting hole penetrates through the rotary cover (2) and the cock (6), and an elastic membrane (62) is arranged on the cock (6); the rotary cover (2) is provided with a first vent hole (25) communicated with the soak solution containing cavity (3), the cock (6) is provided with a second vent hole (61) corresponding to the first vent hole (25) when rotating to a position, and the first vent hole (25) and the second vent hole (61) form an air inlet hole when corresponding to each other; the spiral cover (2) is also provided with a micro exhaust hole (15) with one end communicated with the inside of the bottle body (1) and the other end communicated with the atmosphere.
3. The prostate sampling mechanism of claim 1, wherein: the bottom end of the hollow pipe (4) is detachably connected with a mesh-shaped strainer (18) used for collecting shaken sample tissues on the flexible sampling pad (7).
4. The prostate sampling mechanism of claim 1, wherein: the bottle body (1) comprises an upper bottle body and a lower bottle body which are arranged in a split sealing manner.
5. The prostate sampling mechanism of claim 4, wherein: the utility model discloses a flexible sampling pad, including flexible sampling pad (7), the bottom shutoff of hollow tube (4) has been seted up on flexible sampling pad (7) a plurality of jet orifices (9), and the intercommunication is provided with a plurality ofly to be used for to jet orifice (9) output soak in order to realize jet orifice (9) blowout soak between hollow tube (4) and jet orifice (9), and then with flexible sampling pad (7) go up the connecting pipe that sample tissue washed down, the connecting pipe inlays the dress and sets up the inside at flexible sampling pad (7).
6. The prostate sampling mechanism of claim 1, wherein: the hollow pipe (4) is provided with a one-way valve (5) for preventing the soak in the bottle body (1) from flowing back to the soak containing cavity (3).
7. Sample specimen-box, its characterized in that: the prostate sampling device comprises a box body (10), wherein a plurality of sampling holes (11) are formed in the top end face of the box body (10), and the prostate sampling mechanism as claimed in any one of claims 1 to 6 is arranged in each sampling hole (11).
8. The sampling cartridge of claim 7, wherein: a sliding chute (12) is formed in the side wall of the box body (10), a horizontal sliding plate (13) is arranged in the sliding chute (12) in a sliding mode, and a label position (14) which corresponds to the sampling hole (11) and is used for indicating the sampling position of the prostate sampling mechanism in the sampling hole is arranged on the sliding plate (13); the bottom of the sampling hole (11) is made of transparent materials.
9. The sampling cartridge of claim 7, wherein: the box body (10) comprises an upper box body (101) and a lower box body (102) which are clamped up and down, and the sampling holes (11) are respectively and correspondingly formed in the upper box body (101) and the lower box body (102); the bottle body (1) comprises an upper bottle body and a lower bottle body which are mutually clamped, the upper bottle body is in interference fit with the upper box body (101), and the lower bottle body is in interference fit with the lower box body (102).
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| CN112674072A (en) * | 2020-12-21 | 2021-04-20 | 苗广厚 | Tissue sample storage method for oncology department |
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