CN112672734B - 包含蛋白质和聚烷氧基脂肪酰基表面活性剂的组合物 - Google Patents

包含蛋白质和聚烷氧基脂肪酰基表面活性剂的组合物 Download PDF

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Publication number
CN112672734B
CN112672734B CN201980059505.6A CN201980059505A CN112672734B CN 112672734 B CN112672734 B CN 112672734B CN 201980059505 A CN201980059505 A CN 201980059505A CN 112672734 B CN112672734 B CN 112672734B
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China
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composition
protein
units
fatty acyl
ratio
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CN201980059505.6A
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Chinese (zh)
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CN112672734A (zh
Inventor
J·S·卡茨
S·L·乔丹
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Dow Global Technologies LLC
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Dow Global Technologies LLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Detergent Compositions (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
CN201980059505.6A 2018-09-10 2019-09-06 包含蛋白质和聚烷氧基脂肪酰基表面活性剂的组合物 Active CN112672734B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862729140P 2018-09-10 2018-09-10
US62/729140 2018-09-10
US201962850688P 2019-05-21 2019-05-21
US62/850688 2019-05-21
PCT/US2019/049904 WO2020055679A2 (en) 2018-09-10 2019-09-06 A composition comprising a protein and a polyalkoxy fatty acyl surfactant

Publications (2)

Publication Number Publication Date
CN112672734A CN112672734A (zh) 2021-04-16
CN112672734B true CN112672734B (zh) 2023-04-11

Family

ID=68000095

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980059505.6A Active CN112672734B (zh) 2018-09-10 2019-09-06 包含蛋白质和聚烷氧基脂肪酰基表面活性剂的组合物

Country Status (6)

Country Link
US (1) US20260115292A1 (https=)
EP (1) EP3849519B1 (https=)
JP (1) JP2022500376A (https=)
KR (1) KR20210056349A (https=)
CN (1) CN112672734B (https=)
WO (1) WO2020055679A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022011314A2 (pt) * 2019-12-12 2022-08-23 Nutrition & Biosciences Usa 1 Llc Método para estabilizar uma proteína em solução aquosa durante a purificação e/ou concentração da proteína
US20230242580A1 (en) * 2020-07-15 2023-08-03 Nutrition & Biosciences Usa 1, Llc Bioprocess with reduced fouling on surfaces

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104023748A (zh) * 2011-10-28 2014-09-03 诚信生物公司 含有氨基酸的蛋白质制剂
WO2017044367A1 (en) * 2015-09-11 2017-03-16 Dow Global Technologies Llc A composition comprising a protein and a polyalkoxy fatty compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005011608A1 (de) * 2005-03-14 2006-09-21 Basf Ag Veresterte Alkylalkoxylate als schaumarme Tenside
CA2861402C (en) * 2012-01-30 2021-10-12 Guy Casy Stabilized aqueous antibody compositions
DK3347403T3 (da) 2015-09-11 2020-06-29 Dow Global Technologies Llc Polyalkoxyfedtforbindelse

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104023748A (zh) * 2011-10-28 2014-09-03 诚信生物公司 含有氨基酸的蛋白质制剂
WO2017044367A1 (en) * 2015-09-11 2017-03-16 Dow Global Technologies Llc A composition comprising a protein and a polyalkoxy fatty compound

Also Published As

Publication number Publication date
CN112672734A (zh) 2021-04-16
WO2020055679A3 (en) 2020-05-28
EP3849519A2 (en) 2021-07-21
US20260115292A1 (en) 2026-04-30
WO2020055679A2 (en) 2020-03-19
KR20210056349A (ko) 2021-05-18
JP2022500376A (ja) 2022-01-04
EP3849519B1 (en) 2022-09-21

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