CN112665956A - Solid tumor tissue cleaning combination device and cleaning method - Google Patents

Abstract

The invention relates to the technical field of biomedical devices, in particular to a solid tumor tissue cleaning combination device and a cleaning method, wherein the solid tumor tissue cleaning combination device comprises a reagent storage device and a tissue cleaning device, wherein a plurality of different reagents are stored in the reagent storage device, the reagent storage device is detachably connected with the tissue cleaning device, a reagent releasing device which can release different reagents from the reagent storage device into the tissue cleaning device is arranged in the tissue cleaning device, and the reagent releasing device is detachably connected with the tissue cleaning device. The invention aims to overcome the defects of the prior art, and provides the solid tumor tissue cleaning combination device with the reagent storage device and the tissue cleaning device, which can be used for conveniently cleaning and disinfecting by using different reagents during the collection of the solid tumor tissue, reduces the pollution caused in the sample collection process, and provides guarantee for obtaining qualified tumor tissue.

Description

Solid tumor tissue cleaning combination device and cleaning method

Technical Field

The invention relates to the technical field of biomedical devices, in particular to a solid tumor tissue cleaning combination device and a cleaning method.

Background

The collection and preservation of a clinical fresh tumor tissue specimen after being isolated is crucial to the quality of the specimen. In addition to paying attention to the collection of the specimen, the cleaning, storage and transportation of the specimen are also important to obtain a qualified tumor tissue specimen. In clinical work, a clinician who is responsible for specimen collection is often heavy in daily work, and a disposable simple cleaning and storing device for a fresh tumor tissue sample is not available on the market. When the tumor tissue is collected, the tumor tissue can be simply cleaned or even not cleaned under the limit of environmental conditions, and then the tumor tissue is transferred into a preservation tube filled with preservation solution for transportation. This increases the risk of contamination of the sample and causes irreparable losses to the later experiments. Therefore, there is a clinical need for a simple and convenient device for cleaning and transporting tissue samples, which can solve the above problems, to improve the efficiency of cleaning and storing the samples, avoid secondary pollution of the samples, and protect the environment and the samplers.

Chinese patent CN210560450U discloses a separating device for cleaning solution of human placenta tissue, which utilizes an output mechanism to output the content in the cleaning and separating mechanism through a pipe with a pump, so as to facilitate the separating device for cleaning solution of human placenta tissue to separate the cleaning solution from the placenta tissue, thereby reducing the loss of the placenta tissue after cleaning.

Disclosure of Invention

The invention aims to overcome the defects of the prior art, and provides the solid tumor tissue cleaning combination device with the reagent storage device and the tissue cleaning device, which can be used for conveniently cleaning and disinfecting by using different reagents during the collection of the solid tumor tissue, reduces the pollution caused in the sample collection process, and provides guarantee for obtaining qualified tumor tissue.

In order to solve the technical problems, the invention adopts the technical scheme that:

the utility model provides a solid tumor tissue washs composite set, including storing reagent storage device, the tissue belt cleaning device of a plurality of different reagents, reagent storage device with the tissue belt cleaning device can dismantle the connection, be equipped with in the tissue belt cleaning device and make different reagents release respectively from reagent storage device to the reagent release in the tissue belt cleaning device, reagent release with the tissue belt cleaning device can dismantle the connection.

The reagent storage device is used for storing different reagents, such as disinfectant, cleaning fluid and the like, the tissue cleaning device is used for cleaning and disinfecting tumor tissues, and the reagent storage device and the tissue cleaning device which are detachably connected are used for facilitating the replacement of the reagents in the storage device and the cleaning of the tissue cleaning device and preventing interference and pollution when the reagent storage device is repeatedly used; the reagent releasing device is used for conveniently and pollution-free releasing the reagent in the reagent storage device into the cleaning device, and the detachably connected reagent releasing device and the tissue cleaning device are convenient to clean the reagent releasing device and the tissue cleaning device better on one hand and can be replaced in time when the reagent releasing device is damaged on the other hand. The tissue cleaning device can be placed in the tissue cleaning device at the first time after the tumor sample is separated from the body, so that the secondary pollution of the sample can be avoided, and a sampler does not need to contact the sample in the cleaning process after the tumor sample is placed in the tissue cleaning device, so that the sampler can be effectively protected. The tumor tissue collected is also referred to herein as a sample.

Preferably, the reagent releasing device comprises a connecting unit, a tip puncturing unit for making the reagent in the reagent storing device flow out, and the tip puncturing unit is fixedly connected with the connecting unit; one end of the connecting unit is detachably connected with the reagent storage device, and the other end of the connecting unit is detachably connected with the tissue cleaning device.

Preferably, the tip piercing unit includes a screen and a plurality of pointed protrusions provided on the screen.

Preferably, the tissue washing device comprises a washing main body unit, a waste liquid releasing unit and a waste liquid collecting unit which are sequentially connected, wherein the washing main body unit is arranged at the bottom of the reagent releasing device and detachably connected with the connecting unit.

Preferably, a sample outlet is provided on the cleaning main body unit, and a cover is provided on the sample outlet.

Preferably, the waste liquid releasing unit includes two layers of rotatable filters sequentially arranged from top to bottom, and the filters include an opening portion and a sealing portion connected to each other.

Preferably, reagent storage device include both ends be open end and be equipped with the cavity the shell be equipped with a plurality of reagent memory cell that arranges in proper order in the shell the reagent memory cell bottom is connected with the seal membrane, the shell with reagent memory cell swing joint.

Preferably, the housing is circular in cross section and the reagent storage unit is fan-shaped in cross section.

Preferably, the tissue washing device further comprises a sample storage device which is detachably connected with the tissue washing device.

Preferably, the sample storage device comprises a storage tube body and a sealing cover detachably connected with the storage tube body, and the storage tube body is detachably connected with the sample outlet.

The invention also provides a solid tumor tissue cleaning method, which comprises the following steps:

s1: placing the sample into a tissue washing device;

s2: releasing the reagent in the reagent storage device into the tissue washing device by using the reagent releasing device;

s3: after the oscillating tissue cleaning device cleans the sample, the waste liquid is discharged to a waste liquid collecting unit through a waste liquid releasing unit;

s4: determining the amount of the reagent in the reagent storage device, returning to step S2 if there is any unreleased reagent, and proceeding to step S5 if the release of the reagent is completed;

s5: and taking out the sample after cleaning and disinfection.

Further, the method also includes step S6: and (4) transporting and storing the sample after the sample is transferred to the sample storage device.

Compared with the prior art, the invention has the beneficial effects that:

(1) the tissue cleaning device is immediately placed after the sample is separated, so that the time of exposing the sample to the external environment is reduced, and the secondary pollution of the sample is avoided.

(2) After the sample is put into the device, a sampler is not required to contact the sample in the cleaning and storing processes, so that the sampler can be effectively protected.

(3) The waste liquid collection device can avoid the environment pollution caused by the generated waste liquid.

(4) The invention integrates the functions of sample disinfection, cleaning and preservation, is simple and convenient and easy to use, improves the efficiency of sample cleaning and preservation, and helps a sampler to complete sample collection according to requirements.

Drawings

FIG. 1 is a schematic structural diagram of a solid tumor tissue cleaning assembly according to embodiment 1 of the present invention;

FIG. 2 is a schematic structural view of a tip pricking unit according to the present invention;

FIG. 3 is a schematic view of the filter of the present invention;

FIG. 4 is a schematic diagram of the structure of a reagent storage device according to the present invention;

FIG. 5 is a schematic structural view of the housing of the present invention;

FIG. 6 is a schematic structural view of a reagent storage unit according to the present invention;

FIG. 7 is a schematic diagram of a sample storage device according to the present invention;

FIG. 8 is a schematic structural view of an embodiment 2 of a combined solid tumor tissue washing device according to the present invention;

the graphic symbols are illustrated as follows:

1. a reagent storage device; 11. a housing; 12. a reagent storage unit; 121. a sealing film; 2. a tissue washing device; 21. cleaning the main body unit; 211. a sample outlet; 212. a cover; 22. a waste liquid release unit; 221. a filter; 2211. an opening part; 2212. a sealing part; 23. a waste liquid collection unit; 3. a reagent delivery device; 31. a connection unit; 32. a tip puncturing unit; 321. filtering with a screen; 322. a pointed protrusion; 4. a sample storage device; 41. preserving the pipe body; 42. and (7) sealing the cover.

Detailed Description

The present invention will be further described with reference to the following embodiments. Wherein the showings are for the purpose of illustration only and are shown by way of illustration only and not in actual form, and are not to be construed as limiting the present patent; to better illustrate the embodiments of the present invention, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of an actual product; it will be understood by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted.

The same or similar reference numerals in the drawings of the embodiments of the present invention correspond to the same or similar components; in the description of the present invention, it should be understood that if there is an orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", etc. based on the orientation or positional relationship shown in the drawings, it is only for convenience of describing the present invention and simplifying the description, but it is not intended to indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and are not to be construed as limiting the present patent, and the specific meaning of the terms may be understood by those skilled in the art according to specific circumstances.

Example 1

Fig. 1 to 7 show an embodiment 1 of a combined solid tumor tissue washing device according to the present invention, which includes a reagent storage device 1 storing a plurality of different reagents, and a tissue washing device 2, wherein the reagent storage device 1 is detachably connected to the tissue washing device 2, a reagent releasing device 3 is disposed in the tissue washing device 2 for releasing different reagents from the reagent storage device 1 to the tissue washing device 2, and the reagent releasing device 3 is detachably connected to the tissue washing device 2.

As an embodiment of the present invention, the reagent releasing device 3 includes a connecting unit 31, a tip piercing unit 32 for flowing out the reagent in the reagent storage device 1, the tip piercing unit 32 being fixedly connected to the connecting unit 31; the connection unit 31 has one end detachably connected to the reagent storage device 1 and the other end detachably connected to the tissue washing device 2.

The connecting unit 31 is used for connecting and fastening the reagent storage device 1 and the reagent releasing device 3, the tip puncturing unit 32 is used for puncturing the bottom of the reagent storage device 1, so that the reagent can flow into the tissue cleaning device 2 from the reagent storage device 1 for subsequent cleaning, and the fixedly connected tip puncturing unit 32 and the connecting unit 31 are arranged so that the tip puncturing unit 32 can rotate along with the connecting unit 31. Here, the connection unit 31 may be configured as a mechanism that is rotatably connected to the reagent storage device 1, and when the connection unit 31 is rotated, the distance between the tip puncture unit 32 and the reagent storage device 1 is shortened, and the tip puncture unit 32 punctures the bottom of the reagent storage device 1 to allow the reagent to flow out; specifically, the connection unit 31 and the reagent storage device 1 may be screwed, and the reagents in the reagent storage device 1 may be placed at different heights, so that the connection unit 31 may be rotated to control the rotation height to flow out different reagents, and further, the sequential washing of the samples may be realized by sequentially arranging different reagents as needed in the order from the bottom close to the reagent storage device 1 to the bottom far from the reagent storage device 1. The connecting unit 31 and the reagent storage unit 12 can be made into a structure which can be immovable after being connected with the reagent storage device 1, and the distance between the reagent storage device 1 and the tip puncturing unit 32 is shortened by applying a downward force to the reagent storage unit 12 from the top of the reagent storage device 1, so that the tip puncturing unit 32 punctures the bottom of the reagent storage device 1 and the reagent flows out; specifically, a card slot may be disposed at the top of the connection unit 31, a buckle may be disposed at the bottom of the reagent storage device 1, and the connection between the connection unit 31 and the reagent storage device 1 is realized by the cooperation of the card slot and the buckle. Preferably, the connection unit 31 may be provided in a step-like structure, and the cross-sectional area of the step near the end of the reagent storage device 1 is larger than that of the step far from the end of the reagent storage device 1, so that the reagent storage device 1 can be placed more stably after being connected.

As an embodiment of the present invention, the tip piercing unit 32 includes a strainer 321 and a plurality of pointed protrusions 322 installed on the strainer 321.

The filter 321 is used to allow the reagent to smoothly flow from the reagent releasing device 3 into the tissue washing device 2, and the pointed protrusion 322 is used to pierce the bottom of the reagent storage device 1 to allow the reagent to smoothly flow out. Preferably, the material of the filter screen 321 is stainless steel or plastic with high hardness; the pore diameter is 0.5-1 mm. The pointed protrusion 322 is a net-shaped triangular pyramid, and the top end of the pyramid is provided with a needle point, so that the bottom of the reagent storage device 1 can be conveniently punctured. Further, the tip of the pointed projection 322 is higher than the interface of the two steps of the connection unit 31. Preferably, the pointed protrusion 322 is a net-like mechanism, which facilitates the outflow of the reagent after the bottom of the reagent storage device 1 is pierced.

In one embodiment of the present invention, the tissue washing device 2 includes a washing main unit 21, a waste liquid discharge unit 22, and a waste liquid collection unit 23 connected in this order, and the washing main unit 21 is provided at the bottom of the reagent discharge device 3 and detachably connected to a connection unit 31.

Wash main part unit 21 and provide main washing place for the sample, waste liquid release unit 22 is used for controlling the outflow of waste liquid whether, when wasing the sample, waste liquid release unit 22 is closed, usable reagent soaks the sample and washs this moment, after wasing finishing, can open waste liquid release unit 22, make the waste liquid get into waste liquid collection unit 23, waste liquid collection unit 23 is used for collecting and the storage contaminated reagent, then transport suitable flowing back place, can avoid the polluted environment. Can dismantle washing main part unit 21 and the reagent release 3 of connection, can be convenient for wash washing main part unit 21, remain sample or waste liquid when avoiding used repeatedly, cause the pollution of new sample.

In one embodiment of the present invention, a sample outlet 211 is provided in the cleaning main unit 21, and a cover 212 is provided to cover the sample outlet 211.

The sample outlet 211 facilitates taking out the sample after the sample is washed, and the cover 212 prevents the sample from being contaminated by the outside of the washing main unit 21 when the sample is washed and when the washing main unit 21 is not in use, so that the inside of the washing main unit 21 can have a clean environment.

In one embodiment of the present invention, the waste liquid discharge unit 22 includes two rotatable filters 221 sequentially disposed from top to bottom, and each filter 221 includes an opening 2211 and a sealing 2212 connected to each other.

The filter 221 is provided for the purpose of controlling the outflow of the waste liquid, and the opening 2211 serves as a valve for the outflow of the waste liquid, and the waste liquid can flow from the cleaning main unit 21 through the waste liquid discharge unit 22 into the waste liquid collection unit 23 only when the openings 2211 of the filters 221 of the upper and lower stages are overlapped in the same vertical direction. Preferably, a plurality of opening portions 2211 and a plurality of sealing portions 2212 are arranged and distributed at intervals, and preferably, the opening portions 2211 are fan-shaped filter screens 321, and the pore diameter of the filter screens 321 is 500 micrometers. Preferably, the waste collection unit 23 is a conventional 50mL centrifuge tube. Specifically, the waste liquid collecting unit 23 may be of a tip structure, so as to facilitate waste liquid dumping; can also be made into a flat structure, and is convenient to place on a desktop. Preferably, double-deck filter 221 closely laminates, prevents the weeping, further promotes the management and control of waste liquid release unit 22 to the waste liquid.

As an embodiment of the invention, the reagent storage device 1 comprises a shell 11 with two open ends and a hollow cavity, a plurality of reagent storage units 12 arranged in sequence are arranged in the shell 11, a sealing film 121 is connected to the bottom of the reagent storage unit 12, and the shell 11 is movably connected with the reagent storage unit 12.

The housing 11 serves as a support for the reagent storage unit 12 on the one hand and as a connection for the reagent storage unit 12 and the reagent storage device 1, respectively, and a connection for the connection unit 31 and the reagent storage device 1, respectively, to achieve a connection function. The reagent storage unit 12 is used for storing reagents, and for cleaning, different reagents, such as disinfectant, cleaning solution, etc., can be stored in different reagent storage units 12, and the sealing film 121 disposed at the bottom of the reagent storage unit 12 is used for sealing, and for puncturing by the tip puncturing unit 32 of the reagent releasing device 3, so as to allow the reagents to flow out, and the movable connection of the housing 11 and the reagent storage unit 12 can facilitate replacement of the reagent storage unit 12 and better reagent releasing effect. Specifically, a movable groove may be provided on the housing 11, a protrusion may be provided on the reagent storage unit 12, and the reagent storage unit 12 may be movable up and down in the movable groove of the housing 11.

In one embodiment of the present invention, the housing 11 has a circular cross-section, and the reagent storage unit 12 has a fan-shaped cross-section. The cross section of the main cleaning device can be round, so that the main cleaning device can be conveniently matched with the shell 11, and the shell 11 can be conveniently connected with the main cleaning device. A plurality of reagent storage units 12 may be connected in the housing 11 to facilitate washing of the sample with different reagents. Preferably, a microporous membrane is further disposed on the top of the reagent storage unit 12 to prevent the reagent from being contaminated and to allow the reagent to flow out smoothly after the sealing membrane 121 on the bottom of the reagent storage unit 12 is punctured.

Example 2

Fig. 8 shows an embodiment 2 of the combined solid tumor tissue washing device of the present invention, which is similar to embodiment 1 except that it further comprises a sample storage device 4, and the sample storage device 4 is detachably connected to the tissue washing device 2.

The tissue cleaning device 2 is used for conveniently cleaning and disinfecting by using different reagents when solid tumor tissues are collected, so that pollution caused in the sample collection process is reduced, and a guarantee is provided for obtaining qualified tumor tissues; sample storage device 4 is used for carrying out transient storage in the transportation after the sample washs, and tissue belt cleaning device 2 can be dismantled with sample storage device 4 and be connected and can be convenient for wash or change tissue belt cleaning device 2 or sample storage device 4 to and can only transport sample storage device 4 in carrying out the transportation to the sample after wasing, reduce the device and the volume in the transportation, it is more portable. The solid tumor tissue cleaning and preserving combined device can integrate the functions of sample disinfection, cleaning and preservation, improve the efficiency of sample cleaning and preservation and reduce the pollution of the outside to the sample.

In one embodiment of the present invention, the sample storage device 4 includes a storage tube 41 and a sealing cap 42 detachably connected to the storage tube 41, and the storage tube 41 is detachably connected to the sample outlet 211.

The preservation tube body 41 is used for keeping the cleaned sample, the sealing cover 42 is used for preventing the sample from being polluted by the outside, and the preservation tube body 41 is connected with the sample outlet 211, so that the sample can be transferred from the tissue cleaning device 2 to the preservation tube body 41 in a seamless connection mode, and the pollution to the sample in the transfer process is reduced. Specifically, the storage tube 41 may be a conventional 10mL centrifuge tube.

Example 23

The embodiment of the solid tumor tissue cleaning method comprises the following steps:

s1: placing the sample into the tissue washing device 2;

a cleaning main unit 21 that puts the sample in the tissue cleaning device 2;

s2: releasing the reagent in the reagent storage device 1 into the tissue washing device 2 by using the reagent releasing device 3;

the connection unit 31 is rotated to make the tip puncturing unit 32 puncture the sealing film 121 at the bottom of the reagent storage unit 12 for storing the cleaning agent so that the cleaning agent flows into the cleaning main body unit 21 or to press the reagent storage unit 12 for storing the cleaning agent from top to bottom, the connection between the reagent storage unit for storing the cleaning agent and the housing 11 is broken, the reagent storage unit 12 for storing the cleaning agent enters the step of the connection unit 31, then the tip puncturing unit 32 punctures the sealing film 121 at the bottom of the reagent storage unit 12 for storing the cleaning agent so that the cleaning agent flows into the cleaning main body unit 21, and the pressing is stopped.

Or the connection unit 31 is rotated to make the tip puncturing unit 32 puncture the sealing film 121 at the bottom of the reagent storage unit 12 storing the disinfectant to make the disinfectant flow into the cleaning main body unit 21 or press the reagent storage unit 12 storing the disinfectant from top to bottom, the connection between the reagent storage unit storing the disinfectant and the housing 11 is broken, the reagent storage unit 12 storing the disinfectant enters the step of the connection unit 31, then the tip puncturing unit 32 punctures the sealing film 121 at the bottom of the reagent storage unit 12 storing the disinfectant to make the disinfectant flow into the cleaning main body unit 21, and the pressing is stopped.

S3: after the oscillating tissue cleaning device 2 cleans the sample, the waste liquid is discharged to a waste liquid collecting unit 23 through a waste liquid releasing unit 22;

the sample is washed by shaking, and after the washing is completed, the lower filter 221 of the waste liquid releasing unit 22 is rotated to correspond the openings 2211 of the upper and lower filters 221, so that the communication is realized, and the waste liquid flows into the waste liquid collecting unit 23. When the waste liquid in the cleaning main unit 21 is completely discharged, the lower filter 321 of the waste liquid releasing unit 22 is rotated to completely stagger the openings 2211 of the upper and lower filter 321 layers, thereby closing the waste liquid channel and completing the cleaning or disinfection of the sample.

S4: determining the amount of the reagent in the reagent storage device 1, returning to step S2 if there is any unreleased reagent, and proceeding to step S5 if the release of the reagent is completed;

the reagent storage device 1 is provided with a plurality of reagent storage units 12, different reagents, such as cleaning agents, disinfectants or other reagents, are stored in different reagent storage units 12, the times of cleaning and disinfection of samples can be determined according to needs or according to the reagent storage amount, and after the reagents are used up, the sample cleaning and disinfection work is determined to be completed.

S5: and taking out the sample after cleaning and disinfection.

S6: the samples are transported and stored after being transferred to the sample storage device 4.

After the completion of the washing and sterilization, the cover 212 of the sample outlet 211 is opened, the sample is transferred to the storage tube 41 of the sample storage device 4, and the sealing cover 42 is closed for the transportation and transfer of the sample.

It should be understood that the above-described embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the claims of the present invention.

Claims (10)

1. The utility model provides a solid tumor tissue washs composite set, characterized in that, including storing reagent storage device (1), tissue belt cleaning device (2) of a plurality of different reagents, reagent storage device (1) with tissue belt cleaning device (2) can dismantle the connection, be equipped with in tissue belt cleaning device (2) and make different reagents release reagent release (3) in can following reagent storage device (1) release tissue belt cleaning device (2) respectively, reagent release (3) with tissue belt cleaning device (2) can dismantle the connection.

2. The combination solid tumor tissue washing device according to claim 1, wherein the reagent releasing device (3) comprises a connecting unit (31), a tip puncturing unit (32) for flowing out the reagent in the reagent storing device (1), the tip puncturing unit (32) is fixedly connected with the connecting unit (31); one end of the connecting unit (31) is detachably connected with the reagent storage device (1), and the other end of the connecting unit is detachably connected with the tissue cleaning device (2).

3. The combined solid tumor tissue washing device according to claim 2, wherein the tissue washing device (2) comprises a washing main unit (21), a waste fluid releasing unit (22) and a waste fluid collecting unit (23) which are connected in sequence, and the washing main unit (21) is arranged at the bottom of the reagent releasing device (3) and is detachably connected with the connecting unit (31).

4. The solid tumor tissue washing combination according to any one of claims 1 to 3, wherein a sample outlet (211) is provided on the washing body unit (21), and a cover (212) is provided on the sample outlet (211).

5. The combined solid tumor tissue washing device according to claim 4, wherein the waste fluid releasing unit (22) comprises two layers of rotatable filters (221) arranged in sequence from top to bottom, and the filters (221) comprise an opening portion (2211) and a sealing portion (2212) connected with each other.

6. The combined solid tumor tissue cleaning device according to claim 5, wherein the reagent storage device (1) comprises a housing (11) with two open ends and a hollow cavity, a plurality of reagent storage units (12) arranged in sequence are arranged in the housing (11), a sealing membrane (121) is connected to the bottom of the reagent storage unit (12), and the housing (11) is movably connected with the reagent storage units (12).

7. The solid tumor tissue washing assembly according to claim 6, further comprising a sample storage device (4), wherein the sample storage device (4) is detachably connected with the tissue washing device (2).

8. The solid tumor tissue washing assembly according to claim 7, wherein the sample storage device (4) comprises a storage tube body (41), a sealing cap (42) detachably connected with the storage tube body (41), the storage tube body (41) is detachably connected with the sample outlet (211).

9. A solid tumor tissue cleaning method is characterized by comprising the following steps:

s1: placing the sample in a tissue washing device (2);

s2: releasing the reagent in the reagent storage device (1) into the tissue washing device (2) by using the reagent releasing device (3);

s3: after the oscillating tissue cleaning device (2) cleans the sample, the waste liquid is discharged to a waste liquid collecting unit (23) through a waste liquid releasing unit (22);

s4: determining the amount of the reagent in the reagent storage device 1, returning to step S2 if there is any unreleased reagent, and proceeding to step S5 if the release of the reagent is completed;

s5: and taking out the sample after cleaning and disinfection.

10. The method for cleaning solid tumor tissue according to claim 9, further comprising step S6: and the samples are transported and stored after being transferred to the sample storage device (4).

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