CN112660606A

CN112660606A - Liquid chip kit for early diagnosis of breast cancer

Info

Publication number: CN112660606A
Application number: CN202011457864.8A
Authority: CN
Inventors: 孙探虎
Original assignee: Beijing Dinghan Technology Co Ltd
Current assignee: Beijing Dinghan Technology Co Ltd
Priority date: 2020-12-11
Filing date: 2020-12-11
Publication date: 2021-04-16

Abstract

The invention discloses a liquid-phase chip kit for early diagnosis of breast cancer, which comprises a box body, wherein two circulation cavities are symmetrically formed in the inner bottom of the box body, a first ring-shaped box, a second ring-shaped box and a third ring-shaped box are sequentially arranged at the upper end of the box body from outside to inside, the first ring-shaped box and the box body are integrally formed, the first ring-shaped box, the second ring-shaped box and the third ring-shaped box are sequentially connected in a sliding manner in the vertical direction, an air compression piece is fixedly connected to the inner side of the third ring-shaped box at the upper end of the box body, a box cover is buckled at the outer side of the first ring-shaped box in a sealing manner, and a handle is fixedly connected. Has the advantages that: the invention can store the reagent tube well to improve the transportation capacity, avoid the precipitation in the storage process and form a tower structure to be taken out conveniently.

Description

Liquid chip kit for early diagnosis of breast cancer

Technical Field

The invention relates to the technical field of breast cancer diagnosis, in particular to a liquid chip kit for early diagnosis of breast cancer.

Background

A large number of clinical reports indicate that the key for determining the long-term survival rate of the breast cancer is the early and late stage of the disease course at present, and early diagnosis is the most important measure for improving the prognosis of patients.

The liquid-phase chip reagent is one of the main modes capable of quickly and efficiently detecting breast cancer, and when the existing liquid-phase chip reagent kit for early diagnosis of breast cancer is used for placing the reagent, effective substances in the reagent can be precipitated, so that the detection of the liquid-phase chip is influenced, and meanwhile, the reagent is inconvenient to take and place.

In order to solve the problems, a liquid chip kit for early diagnosis of breast cancer is provided.

Disclosure of Invention

The invention aims to solve the problems in the background art and provides a liquid chip kit for early diagnosis of breast cancer.

In order to achieve the purpose, the invention adopts the following technical scheme: the liquid-phase chip kit for early diagnosis of breast cancer comprises a kit body, wherein two circulation cavities are symmetrically formed in the inner bottom of the kit body, a first annular box, a second annular box and a third annular box are sequentially arranged at the upper end of the kit body from outside to inside, the first annular box and the kit body are integrally formed, the first annular box, the second annular box and the third annular box are sequentially connected in a sliding manner in the vertical direction, an air pressing part is fixedly connected to the upper end of the kit body and the inner side of the third annular box, a box cover is buckled on the outer side of the first annular box in a sealing manner, a handle is fixedly connected to the upper end of the box cover, a first partition plate, a second partition plate and a third partition plate are sequentially and fixedly connected to the inner sides of the first annular box, the second annular box and the third annular box in an anticlockwise direction, and a first water through hole, a second partition plate and a third partition plate are respectively formed in one clockwise side of the second partition plate and the third partition plate, The first annular box, the second annular box, the third annular box, the first partition plate, the first water through hole, the second partition plate, the second water through hole and the third partition plate form a rotary cooling channel, bottom ends on two sides of the rotary cooling channel are respectively communicated with the two circulation cavities, a first water through pipe and a second water through pipe are connected to one ends of the two circulation cavities through the first water through pipe and the second water through pipe, the water pumps are fixedly arranged at the inner bottom of the circulation cavities, and a temperature control device is arranged in each of the two circulation cavities; a plurality of rotary cooling devices are uniformly distributed in the rotary cooling flow channel, each rotary cooling device comprises a rotating column rotatably mounted at the bottom end in the rotary cooling flow channel, a plurality of blades are fixedly connected to the outer side of the rotating column in the circumferential direction, a test tube groove is formed in the upper end of the rotating column, a reagent tube is arranged in the test tube groove, an air bag ring is fixedly glued on the inner wall of the test tube groove, and the upper ends of the plurality of reagent tubes respectively penetrate through the first annular box, the second annular box and the third annular box; the pneumatic part comprises a first barrel, a second barrel and a third barrel which are sequentially sleeved from outside to inside, wherein the first barrel and the second barrel are both of a one-side opening structure, the third barrel is of a two-side closed structure and is fixedly connected with a third annular box, the inner walls of the first barrel, the second barrel and the third barrel are respectively provided with a first limiting groove and a second limiting groove, one end of the second barrel is fixedly connected with a first limiting plate in sealing sliding connection with the first limiting groove, one end of the third barrel is fixedly connected with a second limiting plate in sealing sliding connection with the second limiting groove, the first limiting plate and the second barrel are jointly provided with a first air vent, the second limiting plate and the third barrel are jointly provided with a second air vent, an air pressure device is embedded in the box, one end of the third barrel is communicated with a first air pipe, and one end of the first air pipe, which is far away from the third barrel, is connected with a communicating device, the communicating vessel is connected with a second air pipe and a third air pipe, the second air pipe is connected with the air outlet end of the air pressure equipment, and the second air pipe and the third air pipe are respectively provided with a check valve and an electromagnetic valve.

In the liquid chip kit for early diagnosis of breast cancer, the first ring box, the second ring box and the third ring box are all integrally formed by the vertical ring plate and the horizontal ring plate.

In the liquid chip kit for early diagnosis of breast cancer, the temperature control device comprises temperature sensors symmetrically fixed on the inner walls of one sides of the two circulation cavities and refrigerating sheets symmetrically embedded on the inner walls of one sides of the two circulation cavities, and the temperature sensors and the refrigerating sheets are connected with a controller together.

In the liquid chip kit for early diagnosis of breast cancer, the refrigerating surface and the heating surface of the refrigerating sheet are respectively positioned on the inner side and the outer side of the box body.

In the liquid chip kit for early diagnosis of breast cancer, the upper ends of the first ring box, the second ring box and the third ring box are all provided with pipe holes in clearance fit with the reagent pipes.

In the above liquid chip kit for early diagnosis of breast cancer, the first water passage hole and the second water passage hole are respectively located between the first partition plate and the second partition plate, and between the second partition plate and the third partition plate.

Compared with the prior art, the liquid chip kit for early diagnosis of breast cancer has the advantages that:

1. when the reagent tube storage box is used, the reagent tubes are placed into the inner sides of the air bag rings on the inner walls of the test tube grooves at the upper ends of the rotating columns one by one through the tube holes, the box cover is buckled, the reagent tubes are sealed and stored so as to be convenient to transport, and the air bag rings can absorb shock in the process of transporting the reagent tubes, so that collision is avoided, and the transport capacity is improved.

2. Water pump intermittent type work in two circulation chambeies, the water pump passes through first water service pipe with low temperature water through transmitting to rotatory cooling runner to flow into another circulation intracavity through the second water service pipe and accumulate, at the flow in-process, rivers drive the rotation post through a plurality of blades and rotate, and then drive the reagent pipe rotatory, avoid taking place to deposit in the storage process, influence the condition of use, and carry out the water-cooling to the reagent pipe, the storage environment is better.

3. The pneumatic equipment sequentially passes through the second air pipe, the communicating vessel and the first air pipe to perform one-way inflation on the third cylinder, the second vent hole, the second cylinder, the first vent hole and the first cylinder, so that the overall height of the pneumatic piece is continuously increased, the third annular box, the second annular box and the first annular box are gradually driven to gradually increase, and the third annular box, the second annular box and the first annular box are in a tower-shaped state.

The invention can store the reagent tube well to improve the transportation capacity, avoid the precipitation in the storage process and form a tower structure to be taken out conveniently.

Drawings

FIG. 1 is a front perspective view of a liquid chip kit for early diagnosis of breast cancer according to the present invention;

FIG. 2 is an enlarged schematic view of the structure at A in FIG. 1;

FIG. 3 is a top perspective view of a liquid chip kit for early diagnosis of breast cancer according to the present invention;

fig. 4 is a schematic structural diagram of a hydraulic device of a liquid chip kit for early diagnosis of breast cancer according to the present invention.

In the figure: the air compression device comprises a box body 1, a first annular box 2, a second annular box 3, a third annular box 4, a compression part 5, a box cover 6, a handle 7, a circulation cavity 8, a first partition plate 9, a first water through hole 10, a second partition plate 11, a second water through hole 12, a third partition plate 13, a first water through pipe 14, a second water through pipe 15, a water pump 16, a temperature sensor 17, a refrigerating sheet 18, a controller 19, a pipe hole 20, a rotating column 21, an air bag ring 22, a blade 23, a reagent pipe 24, a first barrel 25, a first limiting plate 26, a second barrel 27, a second limiting plate 28, a third barrel 29, a first air pipe 30, a communicating device 31, a second air pipe 32, a third air pipe 33, a pneumatic device 34, a first air vent 35 and a second air vent 36.

Detailed Description

The following examples are for illustrative purposes only and are not intended to limit the scope of the present invention.

Examples

Referring to fig. 1-4, a liquid chip kit for early diagnosis of breast cancer comprises a box body 1, two circulation cavities 8 are symmetrically formed at the inner bottom of the box body 1, a first ring-shaped box 2, a second ring-shaped box 3 and a third ring-shaped box 4 are sequentially arranged at the upper end of the box body 1 from outside to inside, the first ring-shaped box 2 and the box body 1 are integrally formed, the first ring-shaped box 2, the second ring-shaped box 3 and the third ring-shaped box 4 are sequentially connected in a sliding manner in the vertical direction, a pneumatic part 5 is fixedly connected at the upper end of the box body 1 and at the inner side of the third ring-shaped box 4, a box cover 6 is hermetically buckled at the outer side of the first ring-shaped box 2, a handle 7 is fixedly connected at the upper end of the box cover 6, a first partition plate 9, a second partition plate 11 and a third partition plate 13 are sequentially and fixedly connected at the inner sides of the first ring-shaped, The third annular box 4 is respectively provided with a first water through hole 10 and a second water through hole 12 on one clockwise side of a second partition plate 11 and a third partition plate 13, the first annular box 2, the second annular box 3, the third annular box 4, a first partition plate 9, the first water through hole 10, the second partition plate 11, the second water through hole 12 and the third partition plate 13 form a rotary cooling flow channel, the inner bottom ends of two sides of the rotary cooling flow channel are respectively communicated with two circulation cavities 8 to form a first water through pipe 14 and a second water through pipe 15, the first water through pipe 14 and the second water through pipe 15 are connected with a water pump 16 at one end of the two circulation cavities 8, the water pump 16 is fixedly arranged at the inner bottom of the circulation cavities 8, and a temperature control device is arranged in the two circulation cavities 8;

a plurality of rotary cooling devices are uniformly distributed in the rotary cooling flow channel, each rotary cooling device comprises a rotary column 21 rotatably mounted at the bottom end in the rotary cooling flow channel, each rotary column 21 is made of a copper alloy material, the heat conductivity coefficient is high, a plurality of blades 23 are fixedly connected to the outer side of each rotary column 21 in the circumferential direction, a test tube groove is formed in the upper end of each rotary column 21, reagent tubes 24 are arranged in the test tube grooves, air bag rings 22 are fixedly glued on the inner walls of the test tube grooves, and the upper ends of the reagent tubes 24 respectively penetrate through the first annular box 2, the second annular box 3 and the third annular box 4;

the pneumatic part 5 comprises a first cylinder 25, a second cylinder 27 and a third cylinder 29 which are sequentially sleeved from outside to inside, the first cylinder 25 and the second cylinder 27 are both of a structure with an opening at one side, the third cylinder 29 is of a structure with two closed sides and is fixedly connected with the third ring-shaped box 4, the inner walls of the first cylinder 25, the second cylinder 27 and the third cylinder 29 are respectively provided with a first limiting groove and a second limiting groove, one end of the second cylinder 27 is fixedly connected with a first limiting plate 26 which is in sealing sliding connection with the first limiting groove, one end of the third cylinder 29 is fixedly connected with a second limiting plate 28 which is in sealing sliding connection with the second limiting groove, the first limiting plate 26 and the second cylinder 27 are both provided with a first vent hole 35, the second limiting plate 28 and the third cylinder 29 are both provided with a second vent hole 36, a pneumatic device 34 is embedded in the box body 1, one end of the third cylinder 29 is communicated with a first gas pipe 30, one end of the first air pipe 30, which is far away from the third cylinder 29, is connected with a communicating vessel 31, the communicating vessel 31 is connected with a second air pipe 32 and a third air pipe 33, the second air pipe 32 is connected with an air outlet end of an air pressure device 34, and the second air pipe 32 and the third air pipe 33 are respectively provided with a check valve and an electromagnetic valve.

First ring box 2, second ring box 3 and third ring box 4 are all by vertical ring plate and horizontal ring plate integrated into one piece, and under normal conditions, the lower extreme of first ring box 2, second ring box 3 and third ring box 4 closely laminates with the up end of box body 1.

The temperature control device comprises temperature sensors 17 symmetrically fixed on the inner walls of one sides of the two circulation cavities 8 and refrigeration pieces 18 symmetrically embedded on the inner walls of one sides of the two circulation cavities 8, the temperature sensors 17 and the refrigeration pieces 18 are jointly connected with a controller 19, and the controller 19 controls the water temperature through the refrigeration pieces 18 and the sensors 17.

The refrigerating surface and the heating surface of the refrigerating sheet 18 are respectively positioned at the inner side and the outer side of the box body 1, so that the refrigeration and the heat dissipation are facilitated.

The upper ends of the first annular box 2, the second annular box 3 and the third annular box 4 are all provided with pipe holes 20 in clearance fit with the reagent pipes 24, and the reagent pipes 24 are conveniently placed in the pipe holes 20.

The first water through hole 10 and the second water through hole 12 are respectively positioned between the first partition plate 9 and the second partition plate 11 and between the second partition plate 11 and the third partition plate 13 to form a spiral rotary cooling flow passage.

The working principle of the present invention will now be explained:

when the reagent tube storage box is used, the reagent tubes 24 are placed into the air bag rings 22 on the inner wall of the test tube groove at the upper end of the rotating column 21 one by one through the tube holes 20, the box cover 6 is buckled, sealed storage of the reagent tubes 24 is achieved, and transportation is facilitated, and the air bag rings 22 can absorb shock during transportation of the reagent tubes 24, so that collision is avoided, and transportability is improved.

In the invention, when in storage, the water temperature range in the circulating cavity 8 is set through the controller 19, the water temperature range is the storage temperature range of the reagent pipe 24, the temperature sensor 17 can detect the water temperature in real time and convert the water temperature into an electric signal to be sent to the controller 19, the temperature refrigeration sheet 18 can cool the water in the circulating cavity 8, taking the water pump 16 connected with the first water pipe 14 as an example, the water pump 16 transmits the low-temperature water to a rotary cooling channel through the first water pipe 14 and flows into the other circulating cavity 8 through the second water pipe 15 to be stored, in the flowing process, the water flow drives the rotating column 21 to rotate through the plurality of blades 23, further drives the reagent pipe 24 to rotate, avoids the occurrence of precipitation in the storage process and influences the use condition, and cools the reagent pipe 24 by water, the storage environment is good, after the reagent pipe is used for a certain period, the water pump 16 connected with the second water pipe 15 can work, the plurality of rotary columns 21 and the reagent vessel 24 are rotated in opposite directions.

When a large number of reagent tubes 24 need to be taken out and used, the box cover 6 is opened, the air pressure device 34 charges air to the third cylinder 29, the second vent hole 36, the second cylinder 27, the first vent hole 35 and the first cylinder 25 in a one-way mode sequentially through the second air pipe 32, the communicating vessel 31 and the first air pipe 30, so that the overall height of the air pressure part 5 is continuously increased, the third annular box 4, the second annular box 3 and the first annular box 2 are gradually driven to be gradually increased, and the three are in a tower-shaped state, so that the reagent tubes 24 can be taken out conveniently.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. The utility model provides a liquid chip kit of breast cancer early diagnosis, includes box body (1), its characterized in that, two circulation chambeies (8) have been seted up to the interior bottom symmetry of box body (1), the upper end of box body (1) is equipped with first ring box (2), second ring box (3), third ring box (4) from outside-in proper order, first ring box (2) and box body (1) integrated into one piece, first ring box (2), second ring box (3), third ring box (4) sliding connection in proper order on vertical direction, the upper end of box body (1) just is at inboard fixedly connected with pneumatic part (5) of third ring box (4), the outside sealing lock joint of first ring box (2) has lid (6), the upper end fixedly connected with handle (7) of lid (6), first ring box (2), A first clapboard (9), a second clapboard (11) and a third clapboard (13) are fixedly connected to the inner sides of the second annular box (3) and the third annular box (4) in turn along the anticlockwise direction, a first water through hole (10) and a second water through hole (12) are respectively arranged on one clockwise side of the second clapboard (11) and the third clapboard (13) of the second annular box (3) and the third annular box (4), the first annular box (2), the second annular box (3), the third annular box (4), the first clapboard (9), the first water through hole (10), the second clapboard (11), the second water through hole (12) and the third clapboard (13) form a rotary cooling flow channel, a first water through pipe (14) and a second water through pipe (15) are respectively communicated with the two circulation cavities (8) at the inner bottom ends of the two sides of the rotary cooling flow channel, and a water pump (16) is connected to the first water through pipe (14) and the second water through pipe (15) at one end of the two circulation cavities (8), the water pump (16) is fixedly arranged at the inner bottom of the circulating cavity (8), and temperature control devices are arranged in the two circulating cavities (8) together;

a plurality of rotary cooling devices are uniformly distributed in the rotary cooling flow channel, each rotary cooling device comprises a rotary column (21) rotatably mounted at the bottom end in the rotary cooling flow channel, a plurality of blades (23) are fixedly connected to the outer side of the rotary column (21) in the circumferential direction, a test tube groove is formed in the upper end of the rotary column (21), a reagent tube (24) is arranged in the test tube groove, an air bag ring (22) is fixed on the inner wall of the test tube groove in a gluing mode, and the upper ends of the reagent tubes (24) penetrate through the first annular box (2), the second annular box (3) and the third annular box (4) respectively;

the pneumatic part (5) comprises a first cylinder body (25), a second cylinder body (27) and a third cylinder body (29) which are sequentially sleeved from outside to inside, the first cylinder body (25) and the second cylinder body (27) are of a structure with an opening on one side, the third cylinder body (29) is of a structure with closed two sides and is fixedly connected with a third annular box (4), the inner walls of the first cylinder body (25), the second cylinder body (27) and the third cylinder body (29) are respectively provided with a first limiting groove and a second limiting groove, one end of the second cylinder body (27) is fixedly connected with a first limiting plate (26) in sealing and sliding connection with the first limiting groove, one end of the third cylinder body (29) is fixedly connected with a second limiting plate (28) in sealing and sliding connection with the second limiting groove, the first limiting plate (26) and the second cylinder body (27) are provided with a first vent hole (35) together, and the second limiting plate (28) and the third cylinder body (29) are provided with a second vent hole (36) together, the embedded atmospheric pressure equipment (34) that is equipped with of box body (1), the one end intercommunication of third barrel (29) has first trachea (30), the one end that third barrel (29) was kept away from in first trachea (30) is connected with linker (31), linker (31) are connected with second trachea (32) and third trachea (33), second trachea (32) are connected with the end of giving vent to anger of atmospheric pressure equipment (34), install check valve and solenoid valve on second trachea (32) and third trachea (33) respectively.

2. The liquid chip kit for early diagnosis of breast cancer according to claim 1, wherein the first ring box (2), the second ring box (3) and the third ring box (4) are all integrally formed by a vertical ring plate and a horizontal ring plate.

3. The liquid chip kit for early diagnosis of breast cancer according to claim 1, wherein the temperature control device comprises temperature sensors (17) symmetrically fixed on the inner walls of one side of the two circulation chambers (8) and refrigerating sheets (18) symmetrically embedded on the inner walls of one side of the two circulation chambers (8), and the temperature sensors (17) and the refrigerating sheets (18) are connected with a controller (19) together.

4. The liquid chip kit for early diagnosis of breast cancer according to claim 3, wherein the refrigerating surface and the heating surface of the refrigerating sheet (18) are respectively positioned at the inner side and the outer side of the box body (1).

5. The liquid chip kit for early diagnosis of breast cancer according to claim 1, wherein the upper ends of the first ring box (2), the second ring box (3) and the third ring box (4) are provided with pipe holes (20) which are in clearance fit with the reagent pipes (24).

6. The liquid chip kit for the early diagnosis of breast cancer according to claim 1, wherein the first water through hole (10) and the second water through hole (12) are respectively located between the first partition plate (9) and the second partition plate (11), and between the second partition plate (11) and the third partition plate (13).