CN112654379A

CN112654379A - Occlusion detection device and clamping unit

Info

Publication number: CN112654379A
Application number: CN201980058388.1A
Authority: CN
Inventors: 高畑广行; 上户章吾
Original assignee: JMS Co Ltd
Current assignee: JMS Co Ltd
Priority date: 2018-10-19
Filing date: 2019-10-17
Publication date: 2021-04-13
Anticipated expiration: 2039-10-17
Also published as: WO2020080468A1; JP2020065558A; CN112654379B; JP7176345B2

Abstract

Provided are a blockage detection device and a clamping unit, wherein the load above a specified value can be prevented from being applied to a load detection sensor, and the load detection sensor detects the load caused by the pressure from a pipe. The occlusion detection device 66 includes: a unit main body 61; a substrate 664 attached to the unit main body 61; a load detection sensor 665 which is disposed on the substrate 664 and detects a load due to pressure from the pipe; a lid 62 for opening and closing the unit main body 61; and a load absorbing portion 80 that absorbs a load applied to the substrate 664 via the load detection sensor 665 when a load equal to or greater than a predetermined value is applied to the load detection sensor 665 in a state in which the unit body 61 is closed by the cover 62 and the tube is disposed between the cover 62 and the load detection sensor 665.

Description

Occlusion detection device and clamping unit

Technical Field

The invention relates to an occlusion detection device and a clamping unit.

Background

Conventionally, there is known a blockage detection device including a unit main body, a lid portion that opens and closes the unit main body, and a load detection sensor that detects a load due to pressure from a tube (see, for example, patent document 1).

Documents of the prior art

Patent document

Patent document 1 Japanese patent laid-open No. 2014-83091

Disclosure of Invention

Problems to be solved by the invention

The load detection sensor is broken when a load of a certain level or more is applied. Therefore, it is desirable to suppress the load of a predetermined value or more from being applied to the load detection sensor.

The present invention aims to provide an occlusion detection device and a clamping unit capable of suppressing a load equal to or greater than a predetermined value from being applied to a load detection sensor that detects a load caused by pressure from a tube.

Means for solving the problems

The present invention relates to an occlusion detection device including: a unit main body; a substrate mounted on the unit body; a load detection sensor disposed on the substrate and detecting a load caused by a pressure from the tube; a cover configured to open and close the unit main body; and a load absorbing portion that absorbs a load applied to the substrate via the load detection sensor when a load equal to or greater than a predetermined value is applied to the load detection sensor in a state in which the unit body is closed by the cover and the tube is disposed between the cover and the load detection sensor.

Further, it is preferable that the load absorbing portion includes: a rod-shaped guide member that is disposed so as to penetrate the substrate in the thickness direction and supports the substrate so as to be movable in the thickness direction; and a biasing member that allows movement of the substrate to a side that absorbs a load applied to the load detection sensor when a load equal to or greater than a predetermined value is applied to the load detection sensor, and biases the substrate so that the load detection sensor is positioned at a detection position when a load lower than the predetermined value is applied to the load detection sensor.

Preferably, the biasing member is constituted by 2 spring members, the guide member is provided with 2, the spring members and the guide member are set to 1 group, and the spring members and the guide member are arranged at 2 positions in the surface direction of the substrate, with the portion where the load detection sensor is arranged being sandwiched therebetween.

Preferably, the load absorbing portion further includes a connecting member for connecting the 2 guide members.

The present invention also relates to a clamping unit including the occlusion detection device, the clamping unit clamping a tube by disposing the tube between the unit body and the cover.

ADVANTAGEOUS EFFECTS OF INVENTION

According to the present invention, it is possible to provide an occlusion detection device and a clamp unit that can suppress the application of a load equal to or greater than a predetermined value to a load detection sensor that detects a load due to pressure from a tube.

Drawings

Fig. 1 is a diagram showing an overall configuration of a hemodialysis apparatus according to an embodiment of the present invention.

Fig. 2 is a front view showing the configuration of the clamping unit.

Fig. 3 is a diagram showing an open state of the clamp unit.

Fig. 4 is a perspective view showing a locked state of the clamp unit.

Fig. 5 is a perspective view of the clamp unit as viewed from the lower side.

Fig. 6 is a sectional view taken along line a-a of fig. 4.

Fig. 7 is a sectional view taken along line B-B of fig. 4.

Fig. 8 is a sectional view showing the structure of the load detection unit.

Detailed Description

Hereinafter, a preferred embodiment of the hemodialysis apparatus including the holder unit 60 of the present invention will be described with reference to the drawings. The hemodialysis apparatus according to the present invention purifies blood of a patient suffering from renal insufficiency and/or a patient suffering from drug poisoning, removes excess water in the blood, and supplies water (fluid replacement) to the blood as needed.

First, the overall configuration of the hemodialysis apparatus 1 according to the present embodiment will be described with reference to fig. 1. The hemodialysis apparatus 1 as a dialysis apparatus includes a dialyzer 10 as a hemodialyzer, a blood circuit 20, a dialysate circuit 30, a replenishment liquid line 38, and a console 100. The console 100 is provided with an operation panel 70, a holder unit 60, a part of the blood circuit 20, a part of the dialysate circuit 30, a heater 40 as a temperature adjustment unit, a drug solution pump 231, a substitution pump 39, and a control device 50.

The dialyzer 10 includes a container body 11 formed in a cylindrical shape and a dialysis membrane (not shown) housed inside the container body 11, and the inside of the container body 11 is divided into a blood-side channel and a dialysate-side channel (neither of which is shown) by the dialysis membrane. The container body 11 is formed with a blood inlet 111 and a blood outlet 112 communicating with the blood-side channel, and a dialysate inlet 113 and a dialysate outlet 114 communicating with the dialysate-side channel.

The blood circuit 20 includes an arterial line 21, a venous line 22, a drug line 23, and an overflow line 24. The arterial line 21, the venous line 22, the drug line 23, and the overflow line 24 are each mainly constituted by a flexible tube through which a liquid can flow.

In the present embodiment, the tubes constituting the arterial line 21, the venous line 22, the drug line 23, and the overflow line 24 are flexible tubes made of, for example, polyvinyl chloride (PVC), silicon (Si), or the like. As the tube, for example, a tube having an outer diameter of 5.5mm and an inner diameter of 3.3mm can be used. The hardness of the pipe may be, for example, about 50 to 85 (JIS K7215).

One end of the artery side line 21 is connected to an artery of a subject (dialysis patient), and the other end is connected to the blood inlet 111 of the dialyzer 10. A console 100 is disposed midway in the arterial line 21. In the console 100, the clamp unit 60 and the blood pump 212 are disposed in a portion through which the artery-side tube 21 passes. An artery side clamping portion (clamping portion) 65, a load detection portion 66, and an artery side bubble sensor (bubble detection portion) 67 are disposed in a portion of the clamping unit 60 through which the artery side tube 21 passes. Details of the clamp unit 60 will be described later.

The blood pump 212 is disposed downstream of the clamp unit 60 in the artery-side conduit 21. The blood pump 212 sends out a liquid such as blood and a pre-wash solution inside the artery-side tube 21 by pressing the tube constituting the artery-side tube 21 with rollers.

The vein-side line 22 has one end connected to the blood outlet port 112 of the dialyzer 10 and the other end connected to a vein of a subject (dialysis patient). The venous side chamber 222 and the console 100 are disposed in the middle of the venous side line 22. In the console 100, the clamp unit 60 is disposed in a portion through which the venous-side line 22 passes. A vein-side clamp 69 and a vein-side bubble sensor 68 are disposed in the clamp unit 60 at a portion through which the vein-side tube 22 passes. Details of the clamp unit 60 will be described later.

The venous side chamber 222 is arranged in the venous side line 22 at a position between the dialyzer 10 and the console 100. The venous side lumen 222 holds a prescribed amount (e.g., 20ml) of blood.

The drug line 23 supplies a drug necessary for hemodialysis to the artery-side line 21. One end side (proximal end side) of the drug line 23 is connected to a drug pump 231 that sends out a drug, and the other end side (distal end side) is connected to a position between the blood pump 212 and the dialyzer 10 in the artery line 21.

One end side (base end side) of the overflow line 24 is connected to the venous-side chamber 222. The overflow line 24 discharges the physiological saline, air, and the like flowing through the venous line 22 in the priming step to the outside. An overflow clamp 241 is disposed in the overflow line 24. The overflow clamp 241 opens and closes the flow path of the overflow line 24.

The blood taken out from the artery of the subject (dialysis patient) through the blood circuit 20 described above is introduced into the blood-side channel of the dialyzer 10 while flowing through the artery-side line 21 by the blood pump 212. The blood introduced into the dialyzer 10 is purified by the dialysate flowing through a dialysate circuit 30 described later via a dialysis membrane. The blood purified in the dialyzer 10 flows through the venous-side line 22 and is returned to the subject's vein.

In the present embodiment, the dialysate circuit 30 is constituted by a dialysate circuit 30 of a so-called closed volume control system. The dialysate circuit 30 includes a dialysate chamber 31, a dialysate supply line 32, a dialysate introduction line 33, a dialysate discharge line 34, a drain line 35, a bypass line 36, and a water removal/reverse osmosis pump 37.

The dialysate chamber 31 includes a hard container 311 capable of containing a certain volume (for example, 300ml to 500ml) of dialysate, and a soft diaphragm (diaphragm)312 that partitions the inside of the container 311. The interior of the dialysate chamber 31 is divided by a diaphragm 312 into a liquid feeding accommodation portion 313 and a liquid discharge accommodation portion 314.

The proximal end of the dialysate supply line 32 is connected to a dialysate supply device (not shown), and the distal end is connected to the dialysate chamber 31. The dialysate supply line 32 supplies dialysate to the liquid supply accommodation portion 313 of the dialysate chamber 31.

The dialysate introduction line 33 connects the dialysate chamber 31 and the dialysate introduction port 113 of the dialyzer 10, and introduces the dialysate contained in the fluid feed containing portion 313 of the dialysate chamber 31 into the dialysate-side flow path of the dialyzer 10.

The dialysate extraction line 34 connects the dialysate extraction port 114 of the dialyzer 10 to the dialysate chamber 31, and extracts dialysate discharged from the dialyzer 10 to the drainage storage portion 314 of the dialysate chamber 31.

The proximal end side of the drain line 35 is connected to the dialysate chamber 31, and drains the dialysate contained in the drainage container 314.

The bypass line 36 connects the dialysate extraction line 34 with the drain line 35.

A water scavenging/reverse filtering pump 37 is disposed in the bypass line 36. The water removal/reverse filtration pump 37 is configured by a pump that can be driven so as to send the dialysate in the bypass line 36 to the drain line 35 (water removal direction) and in the dialysate in the bypass line 36 to the dialysate extraction line 34 (reverse filtration direction).

The heater 40 heats the dialysate flowing through the dialysate circuit 30 to a predetermined temperature.

The replenishment liquid line 38 is a line for directly supplying dialysate to the blood circuit 20. As shown in fig. 1, the upstream side of the replenishment liquid line 38 is connected to the dialysate introduction line 33 of the dialysate circuit 30 at a position between the dialysate chamber 31 and the dialysate introduction port 113 of the dialyzer 10. The replenishment liquid line 38 is provided with a replenishment liquid clamp 381. As shown by the solid line in fig. 1, when the downstream side of the replenishment liquid line 38 is connected to a position between the blood pump 212 and the dialyzer 10 in the arterial line 21, the hemofiltration dialysis of the predilution system is performed. As shown by the broken line in fig. 1, when the downstream side of the replenishment liquid line 38 is connected to the venous side chamber 222 in the venous side line 22, the post-dilution hemodialysis is performed.

The clamping unit 60 will be explained.

As shown in fig. 1, the clamp unit 60 is formed in a unit and attached to the console 100. The holding unit 60 holds the tube constituting the arterial side channel 21 and the tube constituting the venous side channel 22 by holding them therebetween. In the grasping unit 60, the tubes constituting the arterial side channel 21 are disposed in the vertical direction on one side in the width direction H, and the tubes constituting the venous side channel 22 are disposed in the vertical direction on the other side in the width direction H.

As shown in fig. 2 to 5, the clamp unit 60 includes a unit main body 61, a lid 62 that opens and closes the unit main body 61, a hinge 63, an opening/closing lever 641, an opening/closing engagement portion 642, a substrate 664 (see fig. 5), and a load detection portion 66. The clamp unit 60 fixes the tube by disposing the tube between the unit main body 61 and the cover 62. The clamp unit 60 fixes the tube constituting the arterial side channel 21 and the tube constituting the venous side channel 22 by pressing the inner surface of the cover 62 against the inner surface side of the unit main body 61 in a state where the tube constituting the arterial side channel 21 and the tube constituting the venous side channel 22 are arranged on the inner surface of the unit main body 61.

The inner surface of the cap 62 constitutes a tube fixing portion for fixing the tube constituting the arterial side tube 21 and the tube constituting the venous side tube 22 with a constant force. Of the members constituting the inner surface of the lid portion 62, as a material of at least a portion to press the tube, for example, a resin material, an ABS resin (acrylonitrile-butadiene-styrene copolymer), an ASA resin (obtained by polymerizing an acrylic rubber in place of the ABS resin), a synthetic resin such as polypropylene, or the like can be used. Thus, the inner surface of the cap 62 can fix the tube constituting the arterial side channel 21 and the tube constituting the venous side channel 22 with an appropriate holding force sufficient for holding without being excessively crushed.

As shown in fig. 2, the hinge 63 is disposed at the other end in the width direction H of the clamp unit 60 when the lid 62 is closed, and connects the lid 62 to the unit main body 61 so as to be rotatable.

The opening/closing lever 641 is provided at one end of the lid 62 in the width direction H when the lid 62 is closed. As shown in fig. 3, the opening/closing engagement portion 642 is provided at one end portion in the width direction H of the inner surface of the unit main body 61 so as to be engageable with the opening/closing lever 641 when the lid portion 62 is closed. The opening/closing lever 641 is operated to open and close the unit main body 61 and the cover 62.

As shown in fig. 3, a main body side artery side tube arrangement portion 611 (tube arrangement portion) and a main body side vein side tube arrangement portion 612 (tube arrangement portion) are formed on the inner surface of the unit main body 61. The main body side artery side tube disposing part 611 and the main body side vein side tube disposing part 612 are disposed on the inner surface of the unit main body 61 so as to be separated in the width direction H of the unit main body 61 and extend linearly. The main body side vein side tube arrangement portion 612 is arranged at a position closer to the hinge portion 63 side in the width direction H than the main body side artery side tube arrangement portion 611.

As shown in fig. 5, a substrate 664 is mounted on the outer surface 613 (see fig. 8) of the unit main body 61. A force sensor 665 (load detection sensor) having a load detection unit 66 (described later and shown in fig. 8) is attached to (disposed on) the 1 st surface 664a of the substrate 664 on the unit main body 61 side (shown in fig. 8).

As shown in fig. 3, a cover side artery side tube disposing part 621 disposed so as to face the main body side artery side tube disposing part 611 when the cover 62 is closed and a cover side vein side tube disposing part 622 disposed so as to face the main body side vein side tube disposing part 612 are formed on the inner surface of the cover 62. The cover-side artery-side tube disposing part 621 and the cover-side vein-side tube disposing part 622 are disposed on the inner surface of the cover 62 so as to be spaced apart in the width direction H of the cover 62 and extend linearly. The cover-side vein-side tube placement portion 622 is disposed on the hinge portion 63 side in the width direction H with respect to the cover-side artery-side tube placement portion 621.

When the cap 62 is closed, the tube constituting the artery-side tube 21 is disposed between the main body-side artery-side tube disposing part 611 and the cap-side artery-side tube disposing part 621, and the tube constituting the vein-side tube 22 is disposed between the main body-side vein-side tube disposing part 612 and the cap-side vein-side tube disposing part 622.

First, the configuration of the main body side artery side tube arrangement portion 611 and the cover side artery side tube arrangement portion 621 will be described.

As shown in fig. 3 and 6, when the lid 62 is closed, the artery side upstream tube pressing portion 601, the artery side clamping portion 65, the load detection portion 66, the artery side bubble sensor 67, and the artery side downstream tube pressing portion 602 are arranged along the main body side artery side tube arrangement portion 611 and the lid side artery side tube arrangement portion 621. In the present embodiment, the artery-side upstream tube pressing portion 601, the artery-side clamping portion 65, the load detection portion 66, the artery-side bubble sensor 67, and the artery-side downstream tube pressing portion 602 are arranged in the clamping unit 60 in order from the upstream side toward the downstream side (from the lower side to the upper side in fig. 1 and 3).

As shown in fig. 3, the main body side artery side tube arrangement portion 611 is arranged on the inner surface of the unit main body 61. In the main body side artery side tube disposing part 611, the housing concave part 601a of the artery side upstream tube pressing part 601, the artery side movable clamping part 651 of the artery side clamping part 65, the load receiving part 662 of the load detecting part 66, the artery side bubble sensor receiving member 672 in which the ultrasonic oscillation part 671 of the artery side bubble sensor 67 is housed, and the housing concave part 602a of the artery side downstream tube pressing part 602 are disposed in line in order from the upstream side toward the downstream side (from the lower side to the upper side in fig. 3) of the liquid flowing through the tube constituting the artery side channel 21.

The cover-side artery-side tube disposing part 621 is disposed on the inner surface of the cover 62, and is disposed so as to face the main-body-side artery-side tube disposing part 611 when the cover 62 is closed. In the cap-side artery-side tube disposing part 621, the pressing convex portion 601b of the artery-side upstream tube pressing part 601, the artery-side pinching receiving part 652 of the artery-side pinching part 65, the load pressing part 663 of the load detecting part 66, the artery-side bubble sensor pressing member 674 in which the ultrasonic wave receiving part 673 of the artery-side bubble sensor 67 is housed, and the pressing convex portion 602b of the artery-side downstream tube pressing part 602 are disposed in this order from the upstream side toward the downstream side (from the lower side to the upper side in fig. 3) of the liquid flowing through the tube constituting the artery-side channel 21.

The pressing convex portion 601b of the artery-side upstream tube pressing portion 601 is disposed so as to face the accommodating concave portion 601a disposed in the unit main body 61 when the lid portion 62 is closed, and presses the tube constituting the artery-side channel 21 on the upstream side (lower side in fig. 3) of the liquid flowing through the artery-side channel 21 in the grasping unit 60.

The artery-side clamp receiver 652 is disposed so as to face the artery-side movable clamp 651 disposed in the unit body 61 when the lid 62 is closed. The artery side clamp receiver 652 and the artery side movable clamp 651 constitute an artery side clamp 65, and hold the tubes constituting the artery side conduit 21 therebetween.

As shown in fig. 3 and 6, the artery side clamping portion 65 includes an artery side movable clamping portion 651 disposed in the unit main body 61, a solenoid 653 disposed in the unit main body 61 and driving the artery side movable clamping portion 651, and an artery side clamping receiving portion 652 disposed in the cap 62. The artery-side clamp receiver 652 is formed to protrude from the inner surface of the cap 62 and extend in the width direction H.

As shown in fig. 6, the artery-side movable clamp portion 651 is formed in a trapezoidal shape having a flat distal end extending in the width direction H and a narrow distal end side in a cross section taken in the direction in which the tube arrangement portion extends. An output shaft 653a of the solenoid 653 is connected to the rear end of the movable artery-side clamping portion 651 so as to be movable forward and backward. The movable artery-side clamping unit 651 clamps a tube constituting the artery-side conduit 21 by the tip of the movable artery-side clamping unit 651 and the tip of the movable artery-side clamping receiver 652 by advancing and retracting the output shaft 653a of the solenoid 653, or opens and closes the artery-side conduit 21.

The artery side clamping unit 65 configured as described above clamps the tube constituting the artery side conduit 21 disposed between the unit main body 61 and the cap 62 by the artery side movable clamping unit 651 and the artery side clamping receiver 652 during normal operation of the hemodialysis apparatus 1.

The artery side clamping unit 65 is opened and closed in the preflushing and blood returning steps using physiological saline. The artery side clamping unit 65 advances and retreats the artery side movable clamping unit 651, or crushes or opens the tube constituting the artery side channel 21, and opens and closes the channel of the artery side channel 21, thereby flowing/stopping the liquid feeding of the liquid flowing in the tube at the upstream side of the artery side bubble sensor 67.

The load detection unit 66 detects a load caused by pressure from a tube constituting the artery-side conduit 21, and can output the load as a voltage value. That is, when the tube is closed, the pressure in the tube becomes positive or negative, the radial direction of the tube changes, and the load changes at the same time, and as a result, the change in the voltage value is detected. As shown in fig. 7, the load detection portion 66 includes a load pressing portion 663, a load receiving portion 662, a force sensor 665 arranged on the substrate 664, and a load absorbing portion 80. The load detector 66 constitutes an occlusion detecting device.

As shown in fig. 3, 6, and 7, the load pressing portion 663 is disposed so as to face the load receiving portion 662 disposed in the unit body 61 when the lid 62 is closed, and presses the tube constituting the artery-side conduit 21. In addition, in order to obtain a voltage value of the same degree as the voltage value output from the load detection portion 66 when the pipe diameter is changed, the load pressing portion 663 may be configured to be adjustable in height, or may be configured to be replaceable with a load pressing portion having a different height.

The load receiving portion 662 receives a load due to pressure from the tube constituting the arterial line 21 pressed by the load pressing portion 663 when the cap 62 is closed. The load receiver 662 transmits a load to the force sensor 665 arranged on the substrate 664. As shown in fig. 8, the load receiving portion 662 has a surface piece portion 662a, a pressing portion 662b, and a transmission shaft portion 662 c. The surface piece portion 662a is disposed on the tube side, and abuts against a tube constituting the artery-side conduit 21 when the cover 62 is closed. The pressing portion 662b and the transmission shaft portion 662c are disposed in the communication hole 615 of the unit body 61. The communication hole 615 is formed to communicate the inner surface of the unit main body 61 with the outer surface 613. The surface piece portion 662a, the pressing portion 662b, and the transmission shaft portion 662c are arranged in this order from the inner surface side of the unit body 61 toward the outer surface 613 side.

As shown in fig. 8, the force sensor 665 is mounted (disposed) on the 1 st surface 664a formed on the unit main body 61 side of the substrate 664. The substrate 664 is attached to the outer surface 613 of the unit main body 61. The substrate 664 is disposed so as to intersect the direction in which the communication holes 615 extend, and blocks the communication holes 615. The substrate 664 has a 1 st surface 664a on the unit main body 61 side abutting against the outer surface 613 of the unit main body 61, and a 2 nd surface 664b on the opposite side of the 1 st surface 664a, which is pressed toward the unit main body 61 side by 2

spring members

82, 82 described later.

The force sensor 665 is disposed on the extension line of the communication hole 615 on the outer surface 613 side of the unit main body 61. The load receiving portion 662 is disposed in the communication hole 615 as described above.

When the unit main body 61 is closed by the lid 62, the tube constituting the artery-side conduit 21 and the load receiving portion 662 are disposed between the load pressing portion 663 of the lid 62 and the force sensor 665 in this order from the load pressing portion 663 side toward the force sensor 665 side.

The force sensor 665 configured as described above detects a load due to the pressure from the pipe acting on the load receiving portion 662, by the load receiving portion 662 moving in the radial direction of the pipe, via the load receiving portion 662. Thus, the force sensor 665 outputs, as a voltage, a load caused by the pressure from the tube constituting the artery-side conduit 21.

As shown in fig. 8, the load absorbing portion 80 is disposed on the substrate 664. When a load equal to or greater than an allowable load (equal to or greater than a predetermined value) is applied to the force sensor 665 in a state where the unit main body 61 is closed by the lid 62 and the tube is disposed between the lid 62 and the force sensor 665, the load absorbing portion 80 absorbs the load applied to the substrate 664 via the force sensor 665. The load absorbing portion 80 includes 2 guide tabs 81 and 81 (guide members), 2 spring members 82 and 82 (biasing members), and a connecting member 83 connecting the

spring members

82 and 82.

The guide 81 and the spring member 82 are configured as a set of the guide 81 and the spring member 82, and in the present embodiment, 2 sets of the guide 81 and the spring member 82 are provided. The 2-group guide 81 and the spring member 82 are disposed at 2 positions on the substrate 664 at a distance from each other in the plane direction thereof, with the force sensor 665 being disposed therebetween.

Each of the 2 guide marks 81 and 81 is formed in a columnar bar shape and extends in the thickness direction of the substrate 664. The guide 81 penetrates the substrate 664 in the thickness direction, and supports the substrate 664 so as to be movable in the thickness direction. The 2 guide marks 81, 81 are arranged separately in the width direction H of the clamp unit 60. The 2 guide marks 81 and 81 are inserted and fixed at one end into a mounting hole 616 formed in the outer surface 613 of the unit main body 61, and protrude at the other end from the outer surface 613 of the unit main body 61. The 2 mounting holes 616 are formed to extend parallel to the communication holes 615, and are arranged in the width direction H of the chucking unit 60 in the plane direction of the substrate 664 with the communication holes 615 interposed therebetween.

The connecting member 83 is formed in a plate shape extending in the width direction H of the clamp unit 60. The connecting member 83 connects the end portions of the other end sides of the 2 guide marks 81, 81 to each other. Both end portions of the connecting member 83 are fixed to the other end portion of the guide 81 by screws 811.

As shown in fig. 8, each of the 2

spring members

82, 82 is formed in a coil shape externally fitted to the guide 81. The spring member 82 is disposed so as to be extendable and retractable between the 2 nd surface 664b of the base plate 664 and the connecting member 83. The spring member 82 allows the movement of the substrate 664 to the side that absorbs the load applied to the force sensor 665 when a load equal to or greater than the allowable load is applied to the force sensor 665, and urges the substrate 664 so that the force sensor 665 is positioned at the detection position when a load lower than the allowable load is applied to the force sensor 665.

Thus, when a load equal to or greater than the allowable load is applied to force sensor 665, movement of substrate 664 to the side that absorbs the load applied to force sensor 665 is allowed, and application of a load equal to or greater than the allowable load (equal to or greater than a predetermined value) to force sensor 665 can be suppressed. In the present embodiment, the spring constant of the spring member 82 is set to a value that does not decrease when a load lower than the allowable load is applied to the force sensor 665, but decreases only when a load equal to or greater than the allowable load is applied to the force sensor 665.

In the load absorbing portion 80 configured as described above, when a pipe is disposed in the clamp unit 60 and when a load greater than or equal to the allowable load is applied to the force sensor 665 when the pipe is disposed between the unit main body 61 and the cover 62, the load in the thickness direction of the substrate 664 can be absorbed by the spring member 82. Therefore, a load equal to or greater than the allowable load (equal to or greater than the predetermined value) can be suppressed from being applied to the force sensor 665. Thus, breakage of the force sensor 665 can be prevented.

In the normal use state of the clamp unit 60, the load applied to the force sensor 665 is a load lower than the allowable load, and therefore the spring member 82 of the load absorbing portion 80 does not contract. That is, in a normal use state, the spring member 82 of the load absorbing portion 80 is held so that the force sensor 665 is located at the detection position without being contracted, and therefore the force sensor 665 can normally detect a load caused by a pressure from the pipe. Thus, the load absorbing portion 80 does not affect the detection of the load by the pressure of the pipe by the force sensor 665 in a normal use state.

Therefore, in a normal use state of the clamp unit 60, when the cap 62 is closed, the cap 62 presses the tube constituting the artery-side conduit 21 against the force sensor 665, and the force sensor 665 detects a load due to the pressure from the tube and outputs the load as a voltage value. The detection value detected by the load detector 66 is transmitted to the controller 50, and it is determined whether or not the tube is closed. Examples of the case of tube occlusion include a case where it is forgotten to release the forceps after the connection of the blood circuit, clogging of the needle tip by thrombus at the time of blood return during treatment, sticking of the needle tip to the blood vessel wall at the time of exsanguination/dialysis, and insufficient blood flow due to the state of the blood vessel at the time of exsanguination/dialysis/blood return.

As shown in fig. 3 and 6, the artery-side air bubble sensor pressing member 674 is disposed so as to face the artery-side air bubble sensor receiving member 672 disposed in the unit main body 61 when the lid portion 62 is closed, and presses the tubes constituting the artery-side conduit 21. An ultrasonic wave receiving portion 673 is disposed inside the artery-side bubble sensor pressing member 674. An ultrasonic oscillation portion 671 is disposed inside the artery-side bubble sensor receiving member 672. The ultrasonic wave receiving portion 673 and the ultrasonic wave oscillating portion 671 constitute an artery side bubble sensor 67. The artery side bubble sensor 67 is a sensor for detecting the presence or absence of bubbles contained in the liquid flowing through the artery side channel 21. The ultrasound receiving portion 673 may be disposed inside the artery-side bubble sensor receiving member 672, and the ultrasound oscillating portion 671 may be disposed inside the artery-side bubble sensor pressing member 674.

When the cover 62 is closed, the artery-side air-bubble sensor pressing member 674 (see fig. 3) presses the tube constituting the artery-side conduit 21 against the artery-side air-bubble sensor receiving member 672 side. The ultrasonic wave receiving unit 673 detects the presence or absence of bubbles by detecting a difference in transmittance between liquid and bubbles by irradiating ultrasonic waves emitted from the ultrasonic wave oscillator 671 to the liquid flowing through the tube constituting the artery-side tube 21.

The pressing convex portion 602b of the artery-side downstream tube pressing portion 602 is disposed so as to face the accommodation concave portion 602a disposed in the unit main body 61 when the lid portion 62 is closed, and presses the tube constituting the artery-side channel 21 on the downstream side (upper side in fig. 3) of the liquid flowing through the artery-side channel 21 in the grasping unit 60.

Next, a configuration in which the main body side vein side tube arrangement portion 612 and the lid side vein side tube arrangement portion 622 are provided when the lid 62 is closed will be described.

As shown in fig. 3, when the cap 62 is closed, the vein-side upstream tube pressing portion 603, the vein-side bubble sensor 68, the vein-side clamping portion 69, and the vein-side downstream tube pressing portion 604 are arranged along the main-body-side vein-side tube arrangement portion 612 and the cap-side vein-side tube arrangement portion 622. In the present embodiment, the vein-side upstream tube pressing portion 603, the vein-side bubble sensor 68, the vein-side clamping portion 69, and the vein-side downstream tube pressing portion 604 are arranged in the clamping unit 60 in order from the upstream side to the downstream side (from the upper side to the lower side in fig. 1 and 3).

As shown in fig. 3, the main body side vein side tube arrangement portion 612 is arranged on the inner surface of the unit main body 61. In the main body side vein side tube disposing part 612, the housing recess 603a of the vein side upstream tube pressing part 603, the vein side air bubble sensor receiving member 682 of the ultrasonic oscillation part 681 housing the vein side air bubble sensor 68 therein, the vein side movable clamping part 691 of the vein side clamping part 69, and the housing recess 604a of the vein side downstream tube pressing part 604 are disposed in order from the upstream side toward the downstream side (from the upper side to the lower side in fig. 3) of the liquid flowing through the tube constituting the vein side channel 22.

The cover-side vein-side tube placement unit 622 is disposed on the inner surface of the cover 62, and is disposed so as to face the main-body-side vein-side tube placement unit 612 when the cover 62 is closed. In the cap-side vein-side tube placement portion 622, the pressing convex portion 603b of the vein-side upstream tube pressing portion 603, the vein-side air bubble sensor pressing member 684 that accommodates the ultrasound wave receiving portion 683 of the vein-side air bubble sensor 68 therein, the vein-side pinching receiving portion 692 of the vein-side pinching portion 69, and the pressing convex portion 604b of the vein-side downstream tube pressing portion 604 are arranged in order from the upstream side toward the downstream side (from the upper side toward the lower side in fig. 3) of the liquid flowing through the tube constituting the vein-side tube path 22.

The pressing convex portion 603b of the vein-side upstream tube pressing portion 603 is disposed so as to face the accommodation concave portion 603a disposed in the unit main body 61 when the lid portion 62 is closed, and presses the tube constituting the vein-side tube path 22 on the upstream side (upper side in fig. 3) of the liquid flowing through the vein-side tube path 22 in the holding unit 60.

The vein-side air bubble sensor pressing member 684 is disposed so as to face the vein-side air bubble sensor receiving member 682 disposed in the unit main body 61 when the cover 62 is closed, and presses the tube constituting the vein-side tube 22. An ultrasound receiving unit 683 is disposed inside the vein-side bubble sensor pressing member 684. An ultrasonic oscillation unit 681 is disposed inside the vein-side bubble sensor receiving member 682. The ultrasonic wave receiving unit 683 and the ultrasonic wave oscillating unit 681 constitute the vein-side bubble sensor 68. The vein-side bubble sensor 68 is a sensor for detecting the presence or absence of bubbles contained in the liquid flowing through the vein-side tube 22. The ultrasound receiving unit 683 may be disposed inside the vein-side air bubble sensor receiving member 682, and the ultrasound oscillating unit 681 may be disposed inside the vein-side air bubble sensor receiving member 684.

When the cover 62 is closed, the vein-side air bubble sensor pressing member 684 (see fig. 3) presses the tube constituting the vein-side tube 22 against the vein-side air bubble sensor receiving member 682. The ultrasonic wave receiving unit 683 can irradiate the liquid flowing through the tube constituting the vein-side tube 22 with the ultrasonic wave emitted from the ultrasonic wave oscillating unit 681, detect the difference in transmittance between the liquid and the bubble, and detect the presence or absence of the bubble.

The vein-side clamp receiving portion 692 is disposed so as to face the vein-side movable clamp portion 691 disposed on the unit main body 61 when the lid portion 62 is closed. The vein-side clamp receiving portion 692 and the vein-side movable clamp portion 691 constitute a vein-side clamp portion 69, and hold a tube constituting the vein-side tube path 22 in a clamped manner.

As shown in fig. 3 and 7, the vein-side clamping unit 69 includes a vein-side movable clamping unit 691 disposed in the unit main body 61, a solenoid 693 disposed in the unit main body 61 and driving the vein-side movable clamping unit 691, and a vein-side clamping receiving unit 692 disposed in the lid 62. The vein-side clamp receiving portion 692 is formed to protrude from the inner surface of the lid portion 62 and extend in the width direction H.

The vein-side movable pinching portion 691 is formed in a trapezoidal shape in which the distal end is formed in a planar shape extending in the width direction H and the width of the distal end side is narrow in a cross section taken along the direction in which the tube arrangement portion extends. An output shaft 693a of the solenoid 693 is connected to the rear end of the vein-side movable holding unit 691 so as to be able to advance and retreat. The vein-side movable holding unit 691 sandwiches a tube constituting the vein-side conduit 22 by the distal end of the vein-side movable holding unit 691 and the distal end of the vein-side holding receiving unit 692 by advancing and retracting the output shaft 693a of the solenoid 693, or opens and closes the vein-side conduit 22.

The vein-side clamping unit 69 configured as described above clamps the tube constituting the vein-side conduit 22 disposed between the unit main body 61 and the lid 62 by the vein-side movable clamping unit 691 and the vein-side clamping receiving unit 692 during normal operation of the hemodialysis apparatus 1.

In addition, the vein-side pinching section 69 is controlled based on the detection result of the air bubbles by the vein-side air bubble sensor 68 or the artery-side air bubble sensor 67. When the vein-side bubble sensor 68 or the artery-side bubble sensor 67 detects bubbles more than a predetermined amount, the vein-side clamping unit 69 moves the vein-side movable clamping unit 691 in and out of the tube constituting the vein-side tube path 22, crushes the tube, and closes the flow path of the vein-side tube path 22, thereby stopping the liquid feeding of the liquid flowing through the tube at a position upstream of the vein-side bubble sensor 68.

The pressing convex portion 604b of the vein-side downstream tube pressing portion 604 is disposed so as to face the accommodating concave portion 604a disposed in the unit main body 61 when the lid portion 62 is closed, and presses the tube constituting the vein-side tube path 22 on the downstream side (lower side in fig. 3) of the liquid flowing through the vein-side tube path 22 in the grip unit 60.

The grasping unit 60 configured as described above can reliably grasp the tube in the grasping unit 60 by only closing the lid 62 in a state where the tube constituting the arterial-side tube 21 and the tube constituting the venous-side tube 22 are disposed in the unit main body 61.

The control device 50 is constituted by an information processing device (computer), and controls the operation of the dialysis apparatus 1 by executing a control program. The control device 50 executes control programs of various steps to control the operation of the hemodialysis apparatus 1. Specifically, the control device 50 controls the operations of the various pumps, clamps, heaters 40, and the like disposed in the blood circuit 20 and the dialysate circuit 30, and executes various steps (a priming step, a bleeding step, a dialysis step, a fluid replacement step, a blood return step, and the like) performed by the hemodialysis apparatus 1.

The hemodialysis apparatus 1 according to the present embodiment described above has the following advantages.

(1) The load detection unit 66 is configured to include: a unit main body 61; a substrate 664 attached to the unit main body 61; a force sensor 665 which is disposed on the substrate 664 and detects a load caused by pressure from the tube; a lid 62 that opens and closes the unit main body 61; and a load absorbing portion 80, wherein the load absorbing portion 80 absorbs a load applied to the substrate 664 via the force sensor 665 when a load equal to or greater than a predetermined value is applied to the force sensor 665 in a state in which the unit body 61 is closed by the cover 62 and the tube is arranged between the cover 62 and the force sensor 665.

Therefore, when the tube is disposed between the unit main body 61 and the cover 62, a load equal to or greater than the allowable load can be suppressed from being applied to the force sensor 665. Therefore, when a load lower than the allowable load is applied to substrate 664, detection of the load of force sensor 665 due to the pressure from the pipe is not affected, and a load equal to or greater than the allowable load can be suppressed from being applied to force sensor 665. This can suppress breakage of force sensor 665.

(2) The load absorbing portion 80 includes: a rod-shaped guide 81 which is disposed so as to penetrate the substrate 664 in the thickness direction and supports the substrate 664 so that the substrate 664 can move in the thickness direction; and a spring member 82, wherein the spring member 82 allows the substrate 664 to move to a side that absorbs the load applied to the force sensor 665 when a load equal to or greater than a predetermined value is applied to the force sensor 665, and the spring member 82 urges the substrate 664 so that the force sensor 665 is positioned at the detection position when a load less than the predetermined value is applied to the force sensor 665. Therefore, when a load equal to or greater than the allowable load is applied to force sensor 665, the load in the thickness direction of substrate 664 can be absorbed by spring member 82 while substrate 664 is guided so as to be movable in the thickness direction by guide 81. This allows the load applied to the force sensor 665 to be absorbed with a simple configuration.

(3) The 2-group spring member 82 and the guide 81 are disposed at 2 positions on the substrate 664 in the plane direction, sandwiching the portion where the force sensor 665 is disposed. This allows the load in the thickness direction of substrate 664 to be absorbed by 2 sets of spring members 82 and guide marks 81 at 2 positions across force sensor 665. Thus, the load applied to the force sensor 665 can be stably absorbed.

(4) The load absorbing portion 80 further has a connecting member 83 to which the 2 guide tabs 81 are connected. This allows the substrate 644 guided by the 2 guide marks 81 to move smoothly in the thickness direction while keeping the 2 guide marks 81 in parallel. This enables stable absorption of the load applied to the force sensor 665.

The preferred embodiments of the hemodialysis apparatus of the present invention have been described above, but the present invention is not limited to the above embodiments and can be modified as appropriate.

For example, in the above-described embodiment, the guide mark 81 (guide member) and the spring member 82 (biasing member) are formed of 2 sets, but the present invention is not limited thereto, and may be formed of 1 set, 3 sets, or more.

In the above embodiment, the 2 guide marks 81 are connected by the connection member 83, but the connection member 83 may not be provided.

In the above embodiment, the substrate 644 to which the force sensor 665 (load detection sensor) is attached is disposed on the outer surface of the unit main body 61, but is not limited thereto. For example, a recessed portion may be formed in the inner surface of the unit main body 61, and a substrate 644 to which a force sensor 665 (load detection sensor) is attached may be disposed in the recessed portion of the inner surface of the unit main body 61.

Description of the reference numerals

1 hemodialysis apparatus (dialysis apparatus)

61 Unit body

62 cover part

66 load detector (blocking detector)

80 load absorbing part

81 guide sign (guide component)

82 spring component (force application component)

83 connecting part

664 base plate

665 force sensor (load detection sensor)

Claims

1. An occlusion detection device is provided with:

a unit main body;

a substrate mounted on the unit body;

a load detection sensor disposed on the substrate and detecting a load caused by a pressure from the tube;

a cover configured to open and close the unit main body; and

and a load absorbing portion that absorbs a load applied to the base plate via the load detection sensor when a load equal to or greater than a predetermined value is applied to the load detection sensor in a state in which the unit body is closed by the cover and the tube is disposed between the cover and the load detection sensor.

2. The occlusion detection device of claim 1,

the load absorbing portion includes:

a rod-shaped guide member that is disposed so as to penetrate the substrate in the thickness direction and supports the substrate so as to be movable in the thickness direction; and

and a biasing member that allows movement of the substrate to a side that absorbs a load applied to the load detection sensor when a load equal to or greater than a predetermined value is applied to the load detection sensor, and biases the substrate so that the load detection sensor is positioned at a detection position when a load lower than the predetermined value is applied to the load detection sensor.

3. The occlusion detection device of claim 2,

the force application member is composed of 2 spring members,

the number of the guide members is set to 2,

the spring members and the guide members are arranged in 1 group, and 2 groups of the spring members and the guide members are arranged at 2 positions on the substrate in the surface direction, with the portion on which the load detection sensor is arranged being sandwiched.

4. The occlusion detection device of claim 3,

the load absorbing portion further has a connecting member connecting the 2 guide members.

5. A clamp unit provided with the occlusion detection device according to any one of claims 1 to 4,

the tube is sandwiched by disposing the tube between the unit main body and the cover.