CN112644019B

CN112644019B - Pharmaceutical preparation 3D printer

Info

Publication number: CN112644019B
Application number: CN202011477742.5A
Authority: CN
Inventors: 杨雯
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-12-15
Filing date: 2020-12-15
Publication date: 2023-01-24
Anticipated expiration: 2040-12-15
Also published as: CN112644019A

Abstract

The invention provides a medicinal preparation 3D printer which comprises a printer body, wherein the printer body comprises a printing spray head assembly, a powder supply and spreading mechanism and a printing platform, and further comprises a first driving device for driving the printing spray head assembly to move and print and a second driving device for driving the powder supply and spreading mechanism to move and spread powder; the first driving device and the second driving device share one group of tracks; the track is erected above the printing platform through a supporting structure; the first driving device drives the printing nozzle assembly to move on the track; the second driving device drives the powder supplying and spreading mechanism to move on the track. By adopting the medicinal preparation 3D printer provided by the invention, the printing nozzle assembly does not work in the powder supplying and powder spreading process; when printing shower nozzle subassembly during operation, supply powder to spread powder mechanism unmovable, once print the in-process promptly, spread the powder and move respectively with printing, reduced and printed the shower nozzle and spread the contaminated possibility of powder in-process, and then prolong the shower nozzle life-span, improved the efficiency of printing the medicine.

Description

Pharmaceutical preparation 3D printer

Technical Field

The invention relates to the technical field of 3D printing of medicines, in particular to a 3D printer for medicinal preparations.

Background

The 3D printing technology is also called additive manufacturing technology, and is to pile up materials layer by layer point by pointStackThe product is manufactured in the manner of (1). Compared with the traditional material reduction manufacturing, the method has the characteristics of short production period, few production procedures, digital production and the like. From the aspect of low-carbon manufacturing, how many materials need to be directly printed by a product in the 3D manufacturing technology, the resource utilization rate is high, and the energy-saving and environment-friendly effects are achieved. Therefore, the method has good application prospect and is a research hotspot in the world at present.

The printing shower nozzle of current pharmaceutic preparation 3D printer spreads powder mechanism with supplying powder and sets up on same moving member, and the two synchronous motion is supplying the powder to spread the in-process of powder, and the printing shower nozzle is followed and is supplied powder to spread powder mechanism and remove, has increaseed the possibility that the printing shower nozzle is polluted by powder, and then influences the life-span of shower nozzle and the efficiency of printing the medicine.

Disclosure of Invention

In order to solve the technical problems, the invention provides a medicinal preparation 3D printer, which has the following specific technical scheme:

the embodiment of the invention provides a medicinal preparation 3D printer which comprises a printer body, a first driving device and a second driving device, wherein the printer body comprises a printing spray head assembly, a powder supply and spreading mechanism and a printing platform, the first driving device is used for driving the printing spray head assembly to print in a moving mode, and the second driving device is used for driving the powder supply and spreading mechanism to spread powder in a moving mode; the first driving device and the second driving device share one group of tracks; the track is erected above the printing platform through a supporting structure; the first driving device drives the printing nozzle assembly to move on the track; the second driving device drives the powder supplying and spreading mechanism to move on the track.

Further, the printer body further comprises a rack and a controller; the second driving device comprises an X-axis movement mechanism; the track comprises a first transverse sliding rail and a second transverse sliding rail; the X-axis movement mechanism includes: a first drive motor; the first sliding assembly and the second sliding assembly are matched with the first transverse sliding rail and the second transverse sliding rail;

the first sliding assembly and the second sliding assembly are respectively connected with the powder supply and spreading mechanism; under the driving action of the first driving motor, the powder supplying and spreading mechanism reciprocates along the X-axis direction.

Further, supply powder spread powder mechanism includes: the powder spreading device comprises a first fixing piece connected with a first sliding assembly, a second fixing piece connected with a second sliding assembly, a powder supplying groove, a second driving motor, a third driving motor, a powder supplying roller and two powder spreading rollers; the powder supply roller is arranged below the powder supply groove, is connected with the second driving motor and is driven by the second driving motor to rotate so as to complete powder supply; the powder paving roller is arranged on two sides of the powder supply groove along the long axis direction of the powder supply groove, is connected with the third driving motor, rotates under the driving of the third driving motor, and has the same motion direction as the powder supplying and paving mechanism.

Further, at least one partition board for dividing the powder supply groove into at least two powder supply spaces is arranged in the powder supply groove, and the partition boards are distributed along the length direction of the powder supply groove; and a powder outlet is formed in the bottom of each powder supply space, and a quantitative powder supply device for controlling the opening or closing of the powder outlet is arranged at the powder outlet.

Further, the length of the powder supply groove is smaller than the width of the printing platform.

Further, the first driving device comprises a Y-axis movement mechanism, a fourth driving motor and a screw rod; the Y-axis movement mechanism includes: the device comprises a bracket, a first longitudinal sliding assembly, a second longitudinal sliding assembly, a third longitudinal sliding assembly, a sliding table and a fifth driving motor; the sliding table is arranged on the bracket and matched with the first longitudinal sliding assembly, and the first longitudinal sliding assembly is connected with a fifth driving motor; the first longitudinal sliding assembly is fixedly connected with the printing nozzle assembly, and the printing nozzle assembly reciprocates along the sliding table under the action of a fifth driving motor; the second longitudinal sliding assembly is arranged at one bottom end of the bracket; the third longitudinal sliding assembly is arranged at the other bottom end of the bracket, the fourth driving motor drives the screw rod to rotate, and the screw rod is in threaded connection with the second longitudinal sliding assembly; the second longitudinal sliding assembly is in sliding connection with the first transverse sliding rail; and the third longitudinal sliding assembly is connected with the second transverse sliding rail in a sliding manner.

Furthermore, a hole-shaped structure is arranged at the lower end of the printing spray head assembly, and a printing spray head is arranged in the hole-shaped structure; the printing nozzle is connected with the ink storage device through a liquid conveying pipe; the ink storage device is internally provided with a bonding agent, and the bonding agent can be uniformly sprayed on the powder in the printing process; the printing spray head assembly is connected with the first longitudinal sliding assembly through a telescopic mechanism; the telescopic mechanism is used for driving the printing nozzle assembly to move up and down along the direction perpendicular to the table top of the printing platform.

Further, the printer body also comprises a Z-axis movement mechanism; the Z-axis movement mechanism comprises a printing platform, a lifting structure arranged below the printing platform and a sixth driving motor, and the printing platform is fixedly connected with the lifting structure; the sixth driving motor drives the lifting structure to move up and down along the Z-axis direction, so that the lifting motion of the printing platform is realized;

the controller is used for controlling the driving motors to rotate, so that the printing nozzle assembly, the X-axis movement mechanism, the Y-axis movement mechanism and the Z-axis movement mechanism move according to a set program.

Further, the powder tank is also included; the powder groove is detachably arranged on the printer body; the cross section of the powder groove is V-shaped.

Furthermore, an auxiliary printing plate is detachably connected to the printing platform; the auxiliary printing plate is made of an acid-resistant and corrosion-resistant material.

The embodiment of the invention provides a medicinal preparation 3D printer which comprises a printer body, wherein the printer body comprises a printing spray head assembly, a powder supply and spreading mechanism and a printing platform, and further comprises a first driving device for driving the printing spray head assembly to move and print and a second driving device for driving the powder supply and spreading mechanism to move and spread powder; the first driving device and the second driving device share one group of tracks; the track is erected above the printing platform through a supporting structure; the first driving device drives the printing nozzle assembly to move on the track; the second driving device drives the powder supplying and spreading mechanism to move on the track. In the using process, firstly, printing raw materials are added into the powder supplying and powder paving mechanism, and then, the second driving device controls the powder supplying and powder paving mechanism to pave powder; after powder spreading is finished, the second driving device controls the powder supply and spreading mechanism to return to the initial position, the first driving device drives the printing nozzle assembly to start printing, and after printing is finished, the first driving device drives the printing nozzle assembly to return to repeat the steps until all the medicines to be printed are printed by the medicinal preparation 3D printer; by adopting the pharmaceutical preparation 3D printer provided by the invention, the scheme that the track is arranged above the printing platform by utilizing the bracket is adopted, so that the distance from the structure for fixing the printing nozzle to the printing platform is increased in the printing process of the printing nozzle assembly, and the nozzle is polluted by effective medicinal powder; on the other hand, print shower nozzle subassembly, supply powder to spread powder mechanism and work respectively, supply powder to spread the powder in-process, print the shower nozzle subassembly and do not work, at the printing in-process, supply powder to spread powder mechanism and not move, reduced and printed the contaminated possibility of shower nozzle, and then improved the efficiency that adopts medicinal preparation 3D printer to print the medicine.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below.

Fig. 1 is a schematic structural diagram of a pharmaceutical preparation 3D printer according to an embodiment of the present invention.

Fig. 2 is a schematic partial structure diagram of a pharmaceutical preparation 3D printer according to an embodiment of the present invention.

Fig. 3 is a schematic top view of a printing platform according to an embodiment of the present invention.

Fig. 4 is a schematic structural diagram of another pharmaceutical preparation 3D printer provided in an embodiment of the present invention.

Fig. 5 is a schematic structural diagram of a lifting structure provided in an embodiment of the present invention.

Fig. 6 is a schematic structural diagram of a powder supplying and spreading mechanism provided in the embodiment of the present invention.

Fig. 7 is a partial structural schematic diagram of another pharmaceutical preparation 3D printer provided by an embodiment of the invention.

Reference numerals:

1 printing nozzle subassembly, 2 confession powder shop powder mechanism, 3 frames, 4 supplementary printing plates. 5, a first transverse sliding rail, 6, a second transverse sliding rail, 7, a first driving motor, 8, a first sliding assembly and 9, a second sliding assembly; 10 a first fixing piece, 11 a second fixing piece, 12 a powder supply groove, 13 a second driving motor, 14 a third driving motor, 16 a powder supply roller and 17 a powder spreading roller; 18 fourth driving motor, 19 screw; 20 a bracket, 21 a first longitudinal sliding assembly, 22 a second longitudinal sliding assembly, 23 a third longitudinal sliding assembly, 24 a sliding table and 25 a fifth driving motor; 28 printing platform, 29 lifting structure, 30 sixth driving motor, 31 supporting arm, 32 powder groove, 33 clapboard, 34 powder supply space, 35 supporting structure and 36 telescoping mechanism.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be obtained by a person skilled in the art without inventive step based on the embodiments of the present invention, are within the scope of protection of the present invention.

Example 1

Referring to fig. 1 to 7, an embodiment of the present invention provides a pharmaceutical preparation 3D printer, including a printer body, where the printer body includes a printing nozzle assembly 1, a powder supply and spreading mechanism 2, and a printing platform 28, and further includes a first driving device for driving the printing nozzle assembly 1 to move and print, and a second driving device for driving the powder supply and spreading mechanism 2 to move and spread powder; the first driving device and the second driving device share one group of tracks; the track is erected above the printing platform 28 by a support structure 35; the first driving device drives the printing nozzle assembly 1 to move on the track; the second driving device drives the powder supplying and spreading mechanism 2 to move on the track.

In this embodiment, the first driving device and the second driving device may be the same or different, and the structure of the first driving device may be as follows: the first driving device comprises a driving motor and a sliding part, wherein the driving motor drives the first threaded rod to rotate; a bracket for supporting can be arranged on the top surface of the sliding piece, and the cross section of the bracket can be U-shaped; one bottom end of the bracket is fixedly connected with the first sliding part, and the other bottom end of the bracket is fixedly connected with the second sliding part; the second driving device has the same structure as the first driving device, the second driving device also comprises a second motor and a second threaded rod, the second motor drives the second threaded rod to rotate, and the bottom of the powder supplying and spreading mechanism 2 is provided with a third sliding part and a fourth sliding part; in this embodiment, for example, one of the above connection relationships is illustrated, the entire apparatus may further include a first rail and a second rail, the first rail and the second rail are both disposed on the printing platform 28 of the printer body, the first rail and the second rail are disposed in parallel, the first sliding member is slidably connected to the first rail, and the second sliding member is slidably connected to the second rail; the two rails are internally provided with a threaded rod, the first threaded rod is arranged in the first rail, the second threaded rod is arranged in the second rail, the driving motor drives the first threaded rod to rotate, the second motor drives the second threaded rod to rotate, a first threaded hole matched with the first threaded rod is formed in the first sliding piece, the first threaded rod is in threaded connection with the first sliding piece through the first threaded hole, and a first through hole with the diameter larger than the outer diameter of the second threaded rod is formed in the second sliding piece; the second threaded rod is in sliding connection with the second sliding piece through the first through hole; a second through hole with the diameter larger than the outer diameter of the first threaded rod is formed in the third sliding part, the first threaded rod penetrates through the third sliding part through the second through hole, the first threaded rod is connected with the third sliding part in a sliding mode, a second threaded hole matched with the second threaded rod is formed in the fourth sliding part, and the second threaded rod is in threaded connection with the fourth sliding part through the second threaded hole; by adopting the arrangement, the driving motor can rotate to drive the first threaded rod to slide in the first track when the first driving device is required to drive the printing nozzle assembly 11 to move for printing, and the second sliding piece is in sliding connection with the second threaded rod, so that the second threaded rod cannot obstruct the sliding of the second sliding piece in the second track no matter the second threaded rod rotates or does not rotate; therefore, the driving motor can drive the printing nozzle arranged on the bracket to move and print; the powder supplying and spreading mechanism 2 is not moved at the moment; in a similar way, when the second driving device is required to drive the powder supplying and spreading device to spread powder, the second motor rotates.

It should be noted that, in the above examples, the means for driving the threaded rod to rotate by the motor belongs to the conventional technical means in the field, and the driving gear may be disposed at the working end of the motor, and the driven gear may be disposed coaxially at the end or on the side wall of the threaded rod, and the driving gear engages with the driven gear and transmits power, at this time, when the motor rotates, the motor may drive the threaded rod to rotate; of course, the above scheme for realizing the rotation of the motor driving threaded rod may also be other existing schemes, the present embodiment does not limit the scheme, and the working end of the motor is the outer end of the motor rotating shaft. In this embodiment, the technical means of driving the threaded rod by the motor is applied to driving the first threaded rod by the motor, and is also applied to driving the second threaded rod by the second motor.

In the using process, firstly, printing raw materials are added into the powder supplying and spreading mechanism 2, and then, the second driving device controls the powder supplying and spreading mechanism 2 to spread powder; after powder spreading is finished, the second driving device controls the powder supply and spreading mechanism 2 to return to the initial position, the first driving device drives the printing nozzle assembly 1 to start printing, after printing is finished, the first driving device drives the printing nozzle assembly 1 to return, and the steps are repeated until all the medicines to be printed are printed by the medicinal preparation 3D printer; by adopting the pharmaceutical preparation 3D printer provided by the invention, the scheme that the track is arranged above the printing platform 28 by utilizing the bracket 20 is adopted, so that the distance from the structure for fixing the printing nozzle to the printing platform 28 is increased in the printing process of the printing nozzle assembly 1, and the effect of dust prevention is achieved; on the other hand, print shower nozzle subassembly 1, supply powder to spread powder mechanism 2 and work respectively, supplying the powder and spread the powder in-process, it is out of work to print shower nozzle subassembly 1, printing the in-process, it is unmovable to supply powder to spread powder mechanism 2, does not have invalid movement in this scheme of print shower nozzle subassembly 1, at once printing the in-process promptly, print shower nozzle subassembly 1 and do not have the process of invalid movement, reduced the contaminated possibility of print shower nozzle, and then improved the purity of the medicine that adopts medicinal preparation 3D printer to print.

In a specific embodiment, the printer body further comprises a frame 3 and a controller; the second driving device comprises an X-axis movement mechanism; the track comprises a first transverse sliding rail 5 and a second transverse sliding rail 6; the X-axis movement mechanism includes: a first drive motor 7; the first sliding assembly and the second sliding assembly are matched with the first transverse sliding rail and the second transverse sliding rail; the first sliding assembly 8 and the second sliding assembly 9 are respectively connected with the powder supplying and spreading mechanism 2; under the driving action of the first driving motor 7, the powder supplying and spreading mechanism 2 reciprocates along the X-axis direction.

In one embodiment, the powder supplying and spreading mechanism 2 includes: a first fixed part 10 connected with the first sliding assembly 8, a second fixed part 11 connected with the second sliding assembly 9, a powder supply groove 12, a second driving motor 13, a third driving motor 14, a powder supply roller 16 and two powder paving rollers 17; the powder supply roller 16 is arranged below the powder supply groove 12, is connected with the second driving motor 13, and is driven by the second driving motor 13 to rotate so as to complete powder supply; the powder paving roller 17 is arranged on two sides of the powder supply groove 12 along the long axis direction of the powder supply groove 12, is connected with a third driving motor, rotates under the driving of the third driving motor, and the motion direction of the powder paving roller 17 is consistent with the motion direction of the powder supply powder paving mechanism 2.

In one embodiment, at least one partition 33 for dividing the powder supply tank 12 into at least two powder supply spaces 34 is provided in the powder supply tank 12, and each partition 33 is distributed along the length direction of the powder supply tank 12; a powder outlet is formed in the bottom of each powder supply space 34, and a quantitative powder supply device for controlling the opening or closing of the powder outlet is arranged at the powder outlet.

Specifically, above-mentioned ration supplies whitewashed device can adopt current ration to supply whitewashed device, its structure can include frame 3, locate the riser in the frame 3, the terminal surface sets up vertical baffle before the riser, the terminal surface is located the articulated quantitative scraper bowl of horizontal hunting respectively of the vertical baffle left and right sides before the riser, two quantitative scraper bowls are close to vertical baffle end uncovered, the terminal surface is located articulated horizontal hunting's unloading mouth directly over the vertical baffle before the riser, the terminal surface is located the vertical baffle before the riser and sets up the hopper directly under, the terminal surface sets up drive unloading mouth articulated shaft and two quantitative scraper bowl horizontal hunting's actuating mechanism behind the riser. In the quantitative powder bagging production process, each medicine bag can be filled with the same amount of powder, so that the blanking accuracy is improved, the fatigue of operators is reduced, and the normal production beat is ensured. In this embodiment, the powder quantitative blanking device in the prior art may be directly installed at the powder outlet to solve the problem that quantitative blanking is required in the present application, specifically, the quantitative powder supply device is installed at the powder outlet to control quantitative blanking of the powder supply and spreading device, in an actual use process, for example, when 12 tablets are printed in a batch, the tablets are arranged in 3*4, at this time, a user may set two partition plates 33 in the powder supply tank 12, the two partition plates 33 divide the powder supply tank 12 into three powder supply spaces 34, the bottoms of the three powder supply spaces 34 are provided with one powder outlet, each powder outlet is provided with one of the above quantitative blanking devices, in a powder spreading process, the powder spreading and supplying device moves to the printing platform 28, the three quantitative blanking devices release a predetermined amount of raw materials at the same time, the powder spreading and supplying device moves to the second row, and the three quantitative blanking devices release a predetermined amount of raw materials at the same time; the powder spreading and supplying device moves to the third row, and the three quantitative blanking devices release the raw materials with the preset amount at the same time; the powder paving and supplying device moves to the fourth row, and the three quantitative blanking devices release the raw materials with the preset amount at the same time; at this time, raw materials to be printed arranged in 3*4 are formed on the printing platform 28, and then the printing nozzle assembly 1 sequentially prints each raw material to be printed; by adopting the scheme, the waste of printing powder can be effectively reduced, and the printing efficiency is improved.

In one embodiment, the length of the powder feeding groove 12 is smaller than the width of the printing platform 28.

In practical application, the length of the powder supply groove 12 is shortened according to the width of the printing platform 28, so that powder to be printed on the printing platform 28 is effectively prevented from being ground into the powder groove 32 beside the printing platform 28 in the powder paving process, invalid printing powder in the powder groove 32 is reduced, and the invalid printing powder is powder which is not printed in the current printing process; in a preferred embodiment, the difference between the length of the powder chute 32 and the width of the printing platform 28 is in the range of 1-4mm; the difference can be equally distributed to the two ends of the powder groove 32, for example, when the difference is 4mm, one end of the powder groove 32 is 2mm away from the edge of the printing platform 28, and the other end is 2mm away from the edge of the printing platform 28.

In one embodiment, the first driving device comprises a Y-axis movement mechanism, a fourth driving motor 18 and a screw 19; the Y-axis movement mechanism includes: the device comprises a bracket 20, a first longitudinal sliding assembly 21, a second longitudinal sliding assembly 22, a third longitudinal sliding assembly 23, a sliding table 24 and a fifth driving motor 25; the sliding table 24 is arranged on the bracket 20, the sliding table 24 is matched with the first longitudinal sliding assembly 21, and the first longitudinal sliding assembly 21 is connected with a fifth driving motor 25; the first longitudinal sliding assembly 21 is fixedly connected with the printing nozzle assembly 1, and the printing nozzle assembly 1 reciprocates along the sliding table 24 under the action of a fifth driving motor 25; the second longitudinal sliding assembly 22 is disposed at a bottom end of the bracket 20; the third longitudinal sliding assembly 23 is arranged at the other bottom end of the bracket 20, the fourth driving motor 18 drives the screw rod 19 to rotate, and the screw rod 19 is in threaded connection with the second longitudinal sliding assembly 22; the second longitudinal sliding assembly 22 is slidably connected with the first transverse sliding rail 5; the third longitudinal sliding assembly 23 is slidably connected to the second transverse sliding rail 6. The sliding components can be in a cuboid block structure.

In one specific embodiment, the lower end of the printing nozzle component 1 is provided with a hole-shaped structure, and a printing nozzle is arranged in the hole-shaped structure; the printing nozzle is connected with the ink storage device through an infusion tube; the ink storage device is internally provided with an adhesive, and the adhesive can be uniformly sprayed on the powder in the printing process; the printing spray head assembly 1 is connected with the first longitudinal sliding assembly 21 through a telescopic mechanism 36; the telescopic mechanism 36 is used for driving the print head assembly 1 to move up and down along a direction perpendicular to the table top of the printing platform 28.

Specifically, the telescopic mechanism 36 may be a telescopic cylinder, the controller is configured to control the telescopic mechanism 36, specifically, the telescopic mechanism 36 is fixedly installed on the first longitudinal sliding assembly 21, a telescopic end of the telescopic mechanism 36 is connected to the top of the printing head assembly 1, the first telescopic assembly extends to a predetermined length according to a printing requirement under control of the controller, so as to ensure that printing work of the printing head assembly 1 is successfully completed, how to control the telescopic mechanism 36 to extend and how long it extends is, and a control method thereof is the prior art, and the embodiment of the present invention is not improved, in this embodiment, a worker only needs to set the above parameters according to actual printing requirements, where the parameters include a distance from the printing head to the printing platform 28 and an extending length of the telescopic mechanism 36; the present embodiment does not specifically limit the above parameters.

In one embodiment, the printer body further comprises a Z-axis motion mechanism; the Z-axis movement mechanism comprises a printing platform 28, a lifting structure 29 arranged below the printing platform 28 and a sixth driving motor 30, and the printing platform 28 is fixedly connected with the lifting structure 29; the sixth driving motor 30 drives the lifting structure 29 to perform lifting movement along the Z-axis direction, so as to realize the lifting movement of the printing platform 28; the controller is used for controlling the rotation of each driving motor, so that the printing nozzle assembly 1, the X-axis movement mechanism, the Y-axis movement mechanism and the Z-axis movement mechanism move according to a set program. The lifting structure 29 is fixedly connected to the frame 3 by means of a support arm 31, in particular a screw.

In one embodiment, a powder tank 32; the powder groove 32 is detachably provided on the printer body. The removal of the powder chute 32 can improve the efficiency of the operation of removing or installing the powder chute 32.

In one embodiment, the powder groove 32 has a "V" shape in cross section. The powder groove 32 is formed in a V shape, so that the powder groove 32 having a V-shaped cross section in the present embodiment is more convenient to clean than the conventional powder groove 32 having a square cross section or the conventional powder groove 32 having a rectangular cross section.

In one embodiment, an auxiliary printing plate 4 is removably attached to the printing platform 28; the auxiliary printing plate 4 is made of an acid-resistant and corrosion-resistant material. Printing platform 28 of current pharmaceutical preparation 3D printer usually with set up at the elevation structure 29 fixed connection of bottom, after having printed a set of medicine, need collect the medicine that is located on printing platform 28, collect the completion after, just can begin to print next time, and another kind of implementation that this embodiment provided, dismantles on printing platform 28 and is connected with supplementary printing plate 4, this supplementary printing plate 4's structure can be with following structure: two grooves are formed in a group of opposite side edges of the bottom surface of the auxiliary printing plate 4, and the grooves are used for facilitating a user to take down a printed tablet and replace another auxiliary printing plate 4 after the printing of the printer is completed so as to improve the working efficiency of the printer.

The embodiment of the invention provides a medicinal preparation 3D printer which comprises a printer body, wherein the printer body comprises a printing spray head assembly 1 and a powder supply and spreading mechanism 2, and further comprises a first driving device for driving the printing spray head assembly 1 to move and print and a second driving device for driving the powder supply and spreading mechanism 2 to move and spread powder. In the using process, firstly, printing raw materials are added into the powder supplying and spreading mechanism 2, and then, the second driving device controls the powder supplying and spreading mechanism 2 to spread powder; after powder spreading is finished, the second driving device controls the powder supply and spreading mechanism 2 to return to the initial position, the first driving device drives the printing nozzle assembly 1 to start printing, after printing is finished, the first driving device drives the printing nozzle assembly 1 to return, and the steps are repeated until all the medicines to be printed are printed by the medicinal preparation 3D printer; by adopting the medicinal preparation 3D printer provided by the invention, the printing spray head assembly 1 and the powder supply and spreading mechanism 2 respectively work, the printing spray head assembly 1 does not work in the powder supply and spreading process, the powder supply and spreading mechanism 2 does not move in the printing process, and the printing spray head assembly 1 does not have invalid movement in the scheme, namely the printing spray head assembly 1 does not have the invalid movement process in the one-time printing process, so that the possibility of polluting a printing spray head is reduced, and the purity of the medicine printed by the medicinal preparation 3D printer is further improved.

The printing method comprises the following steps:

before printing, a three-dimensional CAD model of the pharmaceutical preparation is established, an STL format is exported, and the STL format is imported into a 3D printer controller of the medicine.

(1) Adjusting the printing platform 28 to the highest position, adjusting the powder supply and spreading mechanism 2 to the X-axis initial position, and adjusting the printing nozzle to the Y-axis initial position; the synchronous clear liquid mechanism is adjusted to the lowest height.

(2) The medicine printing powder is filled into a powder supply groove 12; adding a proper amount of adhesive into the ink storage device; adopting a pipeline to supply liquid under negative pressure to enter the spray head;

(3) Starting a power switch and a controller;

(4) The powder supplying and spreading mechanism 2 moves linearly along the X-axis direction, the powder supplying roller 16 rotates to convey the powder in the strip groove to the printing platform 28, and meanwhile, the powder spreading roller 17 rotates forwards to spread the powder on the printing platform 28;

(5) After powder spreading is finished, the printing nozzle assembly 1 moves along the X axis and the Y axis simultaneously, and the adhesive is sprayed on the surface of the powder; printing platform 28 is lowered one level;

(6) The powder supplying and spreading mechanism 2 makes a linear return motion along the X-axis direction, the powder supplying roller 16 rotates to convey the powder in the strip groove to the printing platform 28, and meanwhile, the powder spreading roller 17 rotates forwards to spread the powder on the printing platform 28;

(7) After powder spreading is finished, the spray head moves along the X-axis direction and the Y-axis direction when being printed, and the adhesive is sprayed to the surface of the powder;

(8) Repeating the steps (4) to (7) until printing is completed;

(9) The printed tablets are collected, and a new auxiliary printing plate 4 is placed on the printing platform 28 for the next batch of medicine printing.

Example 2

The present embodiment is different from embodiment 1 in that at least one partition is disposed inside the powder supply groove 12 to divide the powder supply groove 12 into different powder supply areas, preferably 2. The rest is the same as in example 1.

In the use process, according to the number of the printed tablets, the medicine powder can be selectively added into one or more areas of the powder supply groove 12 so as to realize local printing. The printing method is the same as the embodiment.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A medicinal preparation 3D printer comprises a printer body, wherein the printer body comprises a printing spray head assembly, a powder supply and powder spreading mechanism and a printing platform, and is characterized by further comprising a first driving device for driving the printing spray head assembly to print in a moving mode and a second driving device for driving the powder supply and powder spreading mechanism to spread powder in a moving mode; the first driving device and the second driving device share one group of tracks; the track is erected above the printing platform through a supporting structure; the first driving device drives the printing nozzle assembly to move on the track; the second driving device drives the powder supplying and spreading mechanism to move on the track;

the printing spray head assembly and the powder supply and spreading assembly are driven by different driving devices to move respectively, the powder supply and spreading assembly returns to the original position after the action is finished, and the printing spray head assembly starts to move and returns to the original position after the action is finished;

first drive arrangement includes Y axle motion, Y axle motion includes support, slip table, the slip table sets up on the support, Y axle motion includes: the printing nozzle assembly is connected with the first longitudinal sliding assembly through a telescopic mechanism; the telescopic mechanism is used for driving the printing nozzle assembly to move up and down along the direction perpendicular to the table top of the printing platform.

2. The pharmaceutical formulation 3D printer of claim 1, wherein the printer body further comprises a frame, a controller; the second driving device comprises an X-axis movement mechanism; the track comprises a first transverse sliding rail and a second transverse sliding rail; the X-axis movement mechanism includes: a first drive motor; the first sliding assembly is matched with the first transverse sliding rail, and the second sliding assembly is matched with the second transverse sliding rail;

the first sliding assembly and the second sliding assembly are respectively connected with the powder supply and spreading mechanism; the first driving motor drives the second sliding assembly to move along the second transverse sliding rail, and the powder supplying and spreading mechanism reciprocates along the X-axis direction under the driving action of the first driving motor.

3. The pharmaceutical preparation 3D printer of claim 2, wherein the powder supply and spreading mechanism comprises: the powder spreading device comprises a first fixing piece connected with the first sliding assembly, a second fixing piece connected with the second sliding assembly, a powder supplying groove, a second driving motor, a third driving motor, a powder supplying roller and a powder spreading roller; the powder supply roller is arranged below the powder supply groove, is connected with the second driving motor and is driven by the second driving motor to rotate so as to complete powder supply; spread the powder roller and set up in powder supply groove one side along supplying powder groove long axis direction, be connected with third driving motor, rotate under third driving motor's drive, and spread powder roller direction of motion and supply powder to spread powder mechanism direction of motion unanimous.

4. The pharmaceutical preparation 3D printer according to claim 3, wherein at least one partition is provided in the powder supply groove for dividing the powder supply groove into at least two powder supply spaces, each partition being distributed along a length direction of the powder supply groove; each powder supply space's bottom all is provided with the meal outlet department is provided with and is used for controlling the ration that the meal outlet opened or closed supplies whitewashed device.

5. The pharmaceutical preparation 3D printer of claim 4, wherein the length of the powder feed slot is less than the width of the printing platform.

6. The pharmaceutical preparation 3D printer of claim 3, wherein the first drive device comprises a fourth drive motor, a screw; the Y-axis movement mechanism includes: the second longitudinal sliding assembly, the third longitudinal sliding assembly and the fifth driving motor are arranged on the frame; the sliding table is matched with a first longitudinal sliding assembly, and the first longitudinal sliding assembly is connected with a fifth driving motor; the first longitudinal sliding assembly is fixedly connected with the printing nozzle assembly, and the printing nozzle assembly reciprocates along the sliding table under the action of a fifth driving motor; the second longitudinal sliding assembly is arranged at one bottom end of the bracket; the third longitudinal sliding assembly is arranged at the other bottom end of the bracket, the fourth driving motor drives the screw rod to rotate, and the screw rod is in threaded connection with the second longitudinal sliding assembly; the second longitudinal sliding assembly is in sliding connection with the first transverse sliding rail; and the third longitudinal sliding assembly is connected with the second transverse sliding rail in a sliding manner.

7. The pharmaceutical preparation 3D printer according to claim 2, wherein the lower end of the print head assembly is provided with a hole structure, and the print head is arranged in the hole structure; the printing nozzle is connected with the ink storage device through a liquid conveying pipe; the ink storage device is internally provided with an adhesive, and the adhesive can be uniformly sprayed on the powder in the printing process.

8. The pharmaceutical formulation 3D printer of claim 7, wherein the printer body further comprises a Z-axis motion mechanism; the Z-axis movement mechanism comprises a printing platform, a lifting structure arranged below the printing platform and a sixth driving motor, and the printing platform is fixedly connected with the lifting structure; the sixth driving motor drives the lifting structure to move up and down along the Z-axis direction, so that the lifting motion of the printing platform is realized;

9. The pharmaceutical formulation 3D printer of claim 1, further comprising a powder slot; the powder groove is detachably arranged on the printer body; the cross section of the powder groove is V-shaped.

10. The pharmaceutical preparation 3D printer of claim 1, wherein an auxiliary printing plate is removably attached to the printing platform; the auxiliary printing plate is made of an acid-resistant and corrosion-resistant material.