CN112577800A - Pathological tissue machine of drawing materials - Google Patents
Pathological tissue machine of drawing materials Download PDFInfo
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- CN112577800A CN112577800A CN202011433643.7A CN202011433643A CN112577800A CN 112577800 A CN112577800 A CN 112577800A CN 202011433643 A CN202011433643 A CN 202011433643A CN 112577800 A CN112577800 A CN 112577800A
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- pathological
- weighing
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- tissue
- cutting
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01G—WEIGHING
- G01G17/00—Apparatus for or methods of weighing material of special form or property
- G01G17/02—Apparatus for or methods of weighing material of special form or property for weighing material of filamentary or sheet form
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
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- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a pathological tissue sampling machine, which is characterized in that: including casing, pan feeding mouth, discharge gate, cutting device, transfer device, weigh device, data processing apparatus and the quick-witted belt cleaning device of shooing, pathological tissue sends into cutting device through the pan feeding mouth and cuts into the even tissue thin slice of a plurality of thickness, and the rethread discharge gate shifts to weighing and shoots on the device of shooing via the transfer device, the module of shooing of weighing is connected with data processing apparatus, and data processing apparatus will cut the weight and the picture information storage of back pathological tissue and show. The invention can conveniently and quickly cut pathological tissues into thin slices with uniform thickness, comprehensively observe pathological changes from the thin slices, accurately select pathological changes, conveniently make wax blocks and pathological sections of pathological change areas, achieve the process of cutting the tissues by a machine instead of the traditional manual tissue cutting, and establish a new effective method for observing lymph nodes and picking up lymph nodes.
Description
Technical Field
The invention relates to a pathological tissue sampling machine, and belongs to the technical field of conventional pathology.
Background
The most basic work of pathological diagnosis in the pathology department is to take materials from various specimens to be examined, wherein the specimens collected in the pathology department comprise small biopsy specimens, large specimens without plastic deformation and radical treatment specimens of various organs. To accomplish thisThe drawing of specimens with different sizes and instruments conventionally used comprise: scalpel, pathological sampling knife, surgical scissors, brain knife, bone scissors, forceps, bone saw, probe, drag hook, glass slide, magnifier, injector, etc. At present, the soft tissue cutting is performed manually, and no mechanical instrument is available. Biopsy specimens are usually placed directly in an embedding box without further treatment, while larger tissue specimens without plastic deformation and organ specimens for radical treatment are cut out from the specimens in a proper size according to the purpose and requirements of pathological examination, and are subjected to microscopic examination by slide production. For diagnostic purposes, it is critical to obtain the appropriate tissue. The remarks include: 1) the tissue is usually selected at the interface between normal and lesion, i.e. including the lesion itself and the tissue surrounding the lesion; 2) the selected tissue should include the entire hierarchy or important structures of the viscera, e.g., the kidney should include the cortex, medulla, and renal pelvis. 3) The organ with large volume and leaf division should select a plurality of parts according to different tissues. The material should maintain the integrity of the macroscopic specimen as much as possible, and should not be too thick or too thin, generally about 3-5 mm thick and 1.5-2 cm in size2(ii) a 4) The tissue is cut without extrusion, the specimen is skillfully obtained, and the whole process is completed as quickly as possible, particularly the tissue which is easy to autolyze, such as intestinal tract, brain, gland and the like; 5) when the tissue is cut on the same plane, the tissue is firstly tightened, the blade is perpendicular to the plane, the force is proper, the tissue is cut vertically at one time, the cut is neat and not inclined, and the beveling and the back-and-forth pull saw type cutting are forbidden, so that the damage is reduced; 6) when multi-layer tissues are cut, the tissues are generally cut layer by layer according to the tissue level, so that deep tissue organs are prevented from being damaged. Just existing many skills and abilities which need to be mastered, so the problem of uneven material taking quality caused by different levels of material taking personnel and different operation proficiency exists, all instruments for pathologic material taking are manual instruments, the material taking speed is low, the efficiency is low, and the material taking links become weak links for quality control of the pathology department for a long time due to the factors.
Therefore, it is necessary to enhance the research and development of instruments in this link, improve the material drawing efficiency, improve the material drawing quality, realize the homogenization level, and eliminate the influence of human factors.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: the prior art artificially draws materials of pathological tissues slowly, has low efficiency and difficult control of the drawing material quality.
In order to solve the problems, the technical scheme of the invention is to provide a pathological tissue sampling machine, which is characterized in that: including casing, pan feeding mouth, discharge gate, cutting speed adjusting device, transfer device, the device of shooing of weighing, data processing apparatus and the quick-witted belt cleaning device of drawing materials, cutting device establishes inside the casing, including cutting knife tackle and drive cutting knife tackle moving buncher, pan feeding mouth and discharge gate are established on the casing, and pathological tissue sends into cutting device through the pan feeding mouth and cuts into the even tissue thin slice of a plurality of thickness, and the rethread discharge gate shifts to the device of shooing of weighing via transfer device and shoots, the module of shooing of weighing is connected with data processing apparatus, and data processing apparatus stores and shows pathological tissue's weight and picture information after will cutting.
Preferably, the cutting knife tackle includes that the equidistance is fixed the blade that a plurality of laminating settings in the pivot set up, the pivot is established on the support, the support is established in the casing, the pivot is connected with variable speed motor.
Preferably, the distance between adjacent said blades is adjusted by replacing the cutting knife group.
Preferably, the transfer device comprises a material guide plate and a receiving disc, the material guide plate is obliquely arranged below the cutting knife group, the receiving disc is arranged at the discharge port, and the cut pathological tissues are guided into the receiving disc through the material guide plate to be transferred.
Preferably, the device of shooing of weighing includes the weighing module and the module of shooing, casing one side is equipped with the mouth of shooing of weighing, the weighing module is located the mouth of shooing of weighing, the module of shooing is located the top of the mouth of shooing of weighing and is shot the pathological tissue.
Preferably, the data processing device includes computer and display screen, the display screen is established on the casing, the computer is connected the weighing module respectively and is used for carrying out real-time processing and show through the display screen to the pathological tissue picture that the module of shooing was shot to the data that the weighing module measured and the module of shooing.
Preferably, the material drawing machine cleaning device is a cleaning water gun.
Preferably, the distance between adjacent blades is 1-10 mm.
Preferably, the housing is provided with a waste liquid discharge port for discharging the washing waste liquid.
Preferably, a power switch for controlling the speed regulating motor is arranged on the shell.
Compared with the prior art, the invention has the beneficial effects that:
1. the pathological tissue is cut by adopting the pathological tissue sampling machine, so that the pathological tissue can be cut manually;
2. the pathological change tissue with the size of 1cm to 20cm can be quickly processed, and the requirements of pathological work are met;
3. the method has the advantages that the steps are simple, convenient and fast, the thickness is uniform, and the slices of 2mm to 10mm can be cut according to requirements;
4. the cut sheet tissues fall onto the receiving disc through the material guide plate in order, so that stacking, twisting or random stacking is avoided; the original character of the tissue is kept, so that the shape of the focus is convenient to observe and search, and the original position of the focus is recorded;
5. the weight of the specimen can be measured, and the size and the pathological change degree of the pathological change specimen are recorded;
6. the cut thin slice pathological change tissue is easier to observe the pathological change and the relation between the pathological change and the surrounding tissue;
7. the lymph nodes in the lesion tissue can be displayed more conveniently, and the omission of material drawing is avoided;
8. the photographing module can photograph the specimens before and after cutting and store the specimens in a computer so as to facilitate follow-up checking and confirmation;
9. the pathological tissue sampling machine is easy to operate, grasp and popularize;
10. the machine can realize the standardization and standardization of pathological material taking and promote the accuracy and integrity of pathological diagnosis.
The invention provides a mechanized pathological tissue sampling device, which can conveniently and quickly cut pathological tissues into slices with uniform thickness, comprehensively observe pathological changes from the slice tissues, accurately select the pathological changes, conveniently make wax blocks and pathological sections in the pathological change areas and achieve the process of using a machine to cut the tissues to replace the traditional manual tissue cutting.
The tissue cutting, placing, photographing, weighing and information storage functions are comprehensively implemented, and lesion tissues in a large sample size range can be processed under the driving of the speed regulating motor through two rows of rotationally attached circular cutting knife sets; the lesion tissue is placed in the device, so that the tissue can be rapidly cut into tissue slices with regular incisions and uniform thickness within seconds; the tissue slices fall into the receiving tray regularly, so that scattering and stacking are avoided; the lesion and the relation between the lesion and surrounding tissues are easy to observe; the volume, the weight, the pathological change shape and the lesion position of the pathological change tissue can be recorded in time; photographing the specimen before and after drawing the specimen, and storing the photographed specimen in a computer system; establishes a new way for observing lymph nodes and extracting lymph nodes and a preparation method of various focuses.
Drawings
FIG. 1 is a schematic view of an external structure of a pathological tissue sampling machine according to the present invention;
FIG. 2 is a schematic diagram of an internal structure of a pathological tissue sampling machine according to the present invention;
FIG. 3 is a schematic diagram of an internal structure of a pathological tissue sampling machine according to the present invention;
Detailed Description
In order to make the invention more comprehensible, preferred embodiments are described in detail below with reference to the accompanying drawings.
The invention relates to a pathological tissue sampling machine which comprises a shell 1, a feeding port 2, a discharging port 3, a cutting device, a transfer device, a weighing and photographing device, a data processing device 9, a sampling machine cleaning device 10 and a power switch 12. The cutting device is used for cutting pathological tissues and comprises a cutting knife tackle 5 and an adjustable speed motor 11 used for driving the cutting knife tackle 5 to operate, the adjustable speed motor 11 is a national standard grade pure copper adjustable speed motor, the cutting knife tackle 5 adopts a stainless steel cutting knife tackle and is formed by orderly arranging and combining 80 sharp circular blades 52, the blades 52 are fixed on a rotating shaft 51 at equal intervals, the two rotating shafts 51 are arranged inside the shell 1 side by side through a bracket 53, one end of the rotating shaft 51 is connected with the adjustable speed motor 11 through a gear, the rotating speed of the blades 52 is adjustable under the driving of the adjustable speed motor 11, so that tissues with different properties or tissues with different sizes are cut at different speeds, the uniform thickness of the cut is ensured, and the cut tissues can be transferred to the connecting disc 7 in order. The distance between the blades 52 is 1-10mm, 2-5mm and various types, and the distance between every two blades 52 can be adjusted by replacing the cutting knife group 5. The cutting device is controlled by a power switch 12, which power switch 12 is mounted outside the housing 1 and connected to a speed regulating motor 11.
The shell 1 is made of stainless steel metal or plastic materials and has waterproof performance. The cutting device is arranged in the shell 1, a discharge hole 2 is machined in the position, close to the right, of the top of the shell 1, the size of the discharge hole 2 is matched with the length and the width of the cutter set 52, and the cutting device is used for cutting pathological tissues placed into the cutting cutter set 5 of the cutting device. A discharge port 3 is processed at the position close to the right in front of the shell 1, and a receiving disc 7 is placed in the discharge port 3 and used for containing the cut pathological tissues. The weighing and photographing device comprises a weighing module 8 and a photographing module 13, a weighing photographing port 4 is machined in the position, close to the left, in the front of the shell 1, the weighing module 8 is placed in the weighing photographing port 4 and used for weighing the cut pathological tissues and timely and accurately recording the weight of the tissue slices. The photographing module 13 is used for photographing pathological tissues before and after cutting while weighing by installing a camera above the weighing photographing port 4 to be over against the weighing module 9, and timely and accurately recording the corresponding relative position of the tissue slice and the shape and the position of a focus which can be found.
The transfer device comprises a material guide plate 6 and a receiving disc 7, wherein the material guide plate 6 is obliquely arranged below the cutting knife group 5, and the receiving disc 7 is placed at the discharge hole 2. The pathological tissue is cut into a plurality of tissue slices with uniform thickness by the cutting device, and the front edges of the tissue slices firstly fall to contact the material guide plate 6 and gradually slide down along with the cutting process. The tissue slices stop sliding down when the bottoms of the tissue slices contact the receiving tray 7, the whole group of tissue slices lean against the receiving tray 7, and then the tissue slices orderly and completely slide down onto the receiving tray 7 when the receiving tray 7 is pulled out, so that the tissue slices are transferred. The receiving tray 7 is transferred to a weighing and photographing device for weighing and photographing.
Data processing apparatus includes computer and display screen 9, and display screen 9 installs the position that leans on left at the top of casing 1, and weighing module 8, the module of shooing 13 transmit the data of weighing and the pathological tissue picture of shooting for the computer store and show through display screen 9.
The cleaning water gun 10 is installed on the right side surface of the shell 1 and connected with the shell 1 through a spring wire, and is used for cleaning pathological tissues. The cleaning water gun 10 is connected with or separated from the shell 1, so that the cutting device, the material guide plate 6, the receiving disc 7 and the environment are effectively cleaned, and cross contamination of sample quality inspection is avoided. The shell 1, the cutting knife group 5, the material guide plate 6, the connecting disc 7 and the speed regulating motor 11 are all made of waterproof insulating materials.
The bottom of the shell 1 is provided with a waste liquid discharge port 14 for facilitating the discharge of the cleaning waste liquid.
The following explains the working process of the present invention by the cutting process of prostate cancer resection specimen, gastric cancer radical resection specimen, intestinal cancer radical resection specimen of the present invention:
setting the distance between blades 52 of a cutting knife set 5 to be 4mm, vertically placing the prostate cancer resection specimen on the cutting knife set 5 through a discharge port 2, turning on a power switch 12, quickly and uniformly cutting prostate tissues into sheets, dropping the sheets onto a receiving disc 7 through a material guide plate 6, weighing the pathological weight in time, taking pictures of the specimen before and after material taking, and storing the pictures in a computer system; and observing the pathological tissues piece by piece, putting the tissues into an embedding frame from the left side to the right side in sequence, and treating the tissues in a dehydrator to prepare a wax block for subsequent flaking and diagnosis.
Setting the distance between blades 52 of a cutting knife set 5 to be 5mm, transversely placing a gastric cancer radical resection specimen on the cutting knife set 5 through a discharge hole 2, turning on a power switch 12, uniformly cutting gastric cancer tissues into sheets, dropping the sheets onto a receiving disc 7 through a material guide plate 6, weighing the pathological weight in time, taking pictures of the specimen before and after material taking, and storing the pictures in a computer system; observing the pathological tissues piece by piece, selecting the pathological tissues, putting the pathological tissues into an embedding frame, searching lymph nodes in the surrounding adipose tissues, putting the pathological tissues into the embedding frame, treating the pathological tissues in a dehydrator, and manufacturing a wax block for subsequent film making and diagnosis.
Setting the distance between blades 52 of a cutting knife set 5 to be 5mm, vertically placing an intestinal cancer radical cure excision specimen on the cutting knife set through a discharge hole 2, turning on a power switch 12, uniformly cutting intestinal cancer tissues into sheets immediately, dropping the intestinal cancer tissues onto a receiving disc 7 through a material guide plate 6, weighing the pathological weight in time, taking pictures of the specimen before and after material taking, and storing the pictures in a computer system; observing the pathological tissues piece by piece, selecting the pathological tissues, putting the pathological tissues into an embedding frame, searching lymph nodes in the surrounding adipose tissues, putting the pathological tissues into the embedding frame, treating the pathological tissues in a dehydrator, and manufacturing a wax block for subsequent film making and diagnosis.
Claims (10)
1. A pathological tissue sampling machine is characterized in that: including casing (1), pan feeding mouth (2), discharge gate (3), cutting device, transfer device, weigh and shoot device, data processing apparatus (9) and quick-witted belt cleaning device (10) of drawing materials, cutting device establishes inside casing (1), including cutting knife tackle (5) and drive cutting knife tackle (5) moving buncher (11), pan feeding mouth (2) and discharge gate (3) are established on casing (1), and pathological tissue sends into cutting device through pan feeding mouth (2) and cuts into the even tissue thin slice of a plurality of thickness, and rethread discharge gate (3) are transferred to weighing and are shot on the device via transfer device, the module of shooing of weighing is connected with data processing apparatus, and data processing apparatus will cut the weight and the picture information storage of back pathological tissue and show.
2. The pathological tissue sampling machine according to claim 1, wherein: the utility model discloses a cutting knife group (5) is including equidistance fixing blade (52) that a plurality of laminating settings on pivot (51), the pivot is established on support (53), establish in casing (1) support (53), pivot (51) are connected with variable speed motor (11).
3. The pathological tissue sampling machine according to claim 2, wherein: the distance between adjacent blades (52) is adjusted by replacing the cutting knife group (5).
4. The pathological tissue sampling machine as defined in claim 1, wherein: the transfer device comprises a material guide plate (6) and a receiving disc (7), wherein the material guide plate (6) is obliquely arranged below the cutting knife group (5), the receiving disc (7) is arranged at the discharge hole (2), and the cut pathological tissues are transferred in the receiving disc (7) through the material guide plate (6).
5. The pathological tissue sampling machine as defined in claim 1, wherein: the weighing photographing device comprises a weighing module (8) and a photographing module (13), wherein a weighing photographing port (4) is arranged on one side of the shell (1), the weighing module (8) is arranged in the weighing photographing port (4), and the photographing module (13) is arranged above the weighing photographing port (4) to photograph pathological tissues.
6. The pathological tissue sampling machine as defined in claim 1, wherein: the data processing device comprises a computer and a display screen (9), wherein the display screen (9) is arranged on the shell (1), and the computer is respectively connected with the weighing module (8) and the photographing module (13) and is used for processing the data measured by the weighing module (8) and the pathological tissue picture photographed by the photographing module (13) in real time and displaying the data through the display screen (9).
7. The pathological tissue sampling machine as defined in claim 1, wherein: the material drawing machine cleaning device (10) is a cleaning water gun (10).
8. The pathological tissue sampling machine as defined in claim 2, wherein: the distance between the adjacent blades (52) is 1-10 mm.
9. The pathological tissue sampling machine as defined in claim 1, wherein: and a waste liquid discharge port (14) for discharging cleaning waste liquid is arranged on the shell (1).
10. The pathological tissue sampling machine as defined in claim 1, wherein: and a power switch (12) for controlling the speed regulating motor (11) is arranged on the shell (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011433643.7A CN112577800A (en) | 2020-12-10 | 2020-12-10 | Pathological tissue machine of drawing materials |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011433643.7A CN112577800A (en) | 2020-12-10 | 2020-12-10 | Pathological tissue machine of drawing materials |
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| CN112577800A true CN112577800A (en) | 2021-03-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202011433643.7A Pending CN112577800A (en) | 2020-12-10 | 2020-12-10 | Pathological tissue machine of drawing materials |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113848085A (en) * | 2021-08-12 | 2021-12-28 | 澎立检测技术(上海)有限公司 | Pathological hard tissue section system |
| CN113848085B (en) * | 2021-08-12 | 2024-05-31 | 澎立检测技术(上海)有限公司 | Pathological hard tissue slicing system |
-
2020
- 2020-12-10 CN CN202011433643.7A patent/CN112577800A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113848085A (en) * | 2021-08-12 | 2021-12-28 | 澎立检测技术(上海)有限公司 | Pathological hard tissue section system |
| CN113848085B (en) * | 2021-08-12 | 2024-05-31 | 澎立检测技术(上海)有限公司 | Pathological hard tissue slicing system |
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Application publication date: 20210330 Assignee: Shanghai Qiaoda medical technology center Assignor: Zhongshan Hospital, Fudan University Contract record no.: X2021980005480 Denomination of invention: A pathological tissue sampling machine License type: Exclusive License Record date: 20210628 |