CN112514926B - 一种灭活冠状病毒的天然植萃精油消毒剂及应用 - Google Patents
一种灭活冠状病毒的天然植萃精油消毒剂及应用 Download PDFInfo
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- CN112514926B CN112514926B CN202011474411.6A CN202011474411A CN112514926B CN 112514926 B CN112514926 B CN 112514926B CN 202011474411 A CN202011474411 A CN 202011474411A CN 112514926 B CN112514926 B CN 112514926B
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- oil
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- 239000000419 plant extract Substances 0.000 title claims abstract description 46
- 230000000415 inactivating effect Effects 0.000 title claims abstract description 14
- 239000010668 rosemary oil Substances 0.000 claims abstract description 14
- 229940119201 cedar leaf oil Drugs 0.000 claims abstract description 13
- 229940058206 rosemary oil Drugs 0.000 claims abstract description 13
- 239000010670 sage oil Substances 0.000 claims abstract description 13
- 239000001789 thuja occidentalis l. leaf oil Substances 0.000 claims abstract description 13
- 239000010648 geranium oil Substances 0.000 claims abstract description 11
- 235000019717 geranium oil Nutrition 0.000 claims abstract description 11
- 241000711467 Human coronavirus 229E Species 0.000 claims abstract description 8
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 6
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- 230000000694 effects Effects 0.000 abstract description 6
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- 231100000252 nontoxic Toxicity 0.000 abstract description 3
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- 231100000419 toxicity Toxicity 0.000 abstract description 3
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 241000700605 Viruses Species 0.000 description 12
- 238000002474 experimental method Methods 0.000 description 7
- 235000019484 Rapeseed oil Nutrition 0.000 description 6
- 230000005764 inhibitory process Effects 0.000 description 6
- 239000013642 negative control Substances 0.000 description 6
- 238000001256 steam distillation Methods 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 230000003013 cytotoxicity Effects 0.000 description 4
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- 238000009472 formulation Methods 0.000 description 4
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- 208000001528 Coronaviridae Infections Diseases 0.000 description 3
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- 231100001083 no cytotoxicity Toxicity 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- 241000282412 Homo Species 0.000 description 2
- 208000025370 Middle East respiratory syndrome Diseases 0.000 description 2
- 240000004277 Pelargonium radens Species 0.000 description 2
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- 238000001132 ultrasonic dispersion Methods 0.000 description 2
- 240000005020 Acaciella glauca Species 0.000 description 1
- 241000218645 Cedrus Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 244000183685 Citrus aurantium Species 0.000 description 1
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- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000248349 Citrus limon Species 0.000 description 1
- 240000002319 Citrus sinensis Species 0.000 description 1
- 235000005976 Citrus sinensis Nutrition 0.000 description 1
- 235000018782 Dacrydium cupressinum Nutrition 0.000 description 1
- 241000208152 Geranium Species 0.000 description 1
- 244000309467 Human Coronavirus Species 0.000 description 1
- 241000721662 Juniperus Species 0.000 description 1
- 235000014556 Juniperus scopulorum Nutrition 0.000 description 1
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- 235000013697 Pinus resinosa Nutrition 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 244000178231 Rosmarinus officinalis Species 0.000 description 1
- 235000008691 Sabina virginiana Nutrition 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
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- 150000001299 aldehydes Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 235000019519 canola oil Nutrition 0.000 description 1
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- 230000010261 cell growth Effects 0.000 description 1
- 230000003833 cell viability Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- MAYPHUUCLRDEAZ-UHFFFAOYSA-N chlorine peroxide Chemical compound ClOOCl MAYPHUUCLRDEAZ-UHFFFAOYSA-N 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 241001493065 dsRNA viruses Species 0.000 description 1
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- 230000007774 longterm Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- VMGAPWLDMVPYIA-HIDZBRGKSA-N n'-amino-n-iminomethanimidamide Chemical compound N\N=C\N=N VMGAPWLDMVPYIA-HIDZBRGKSA-N 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 230000007505 plaque formation Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- BOLDJAUMGUJJKM-LSDHHAIUSA-N renifolin D Natural products CC(=C)[C@@H]1Cc2c(O)c(O)ccc2[C@H]1CC(=O)c3ccc(O)cc3O BOLDJAUMGUJJKM-LSDHHAIUSA-N 0.000 description 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 description 1
- 235000002020 sage Nutrition 0.000 description 1
- 235000001520 savin Nutrition 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/36—Rutaceae [Rue family], e.g. lime, orange, lemon, corktree or pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Botany (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Birds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
Claims (5)
Priority Applications (1)
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CN202011474411.6A CN112514926B (zh) | 2020-12-14 | 2020-12-14 | 一种灭活冠状病毒的天然植萃精油消毒剂及应用 |
Applications Claiming Priority (1)
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CN202011474411.6A CN112514926B (zh) | 2020-12-14 | 2020-12-14 | 一种灭活冠状病毒的天然植萃精油消毒剂及应用 |
Publications (2)
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CN112514926A CN112514926A (zh) | 2021-03-19 |
CN112514926B true CN112514926B (zh) | 2021-10-01 |
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Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1500477A (zh) * | 2002-11-13 | 2004-06-02 | 丛繁滋 | 带有植物芳香气息的速效气雾剂及其制备方法 |
CN1805784A (zh) * | 2003-05-11 | 2006-07-19 | 内盖夫研发局属本古里昂大学 | 胶囊化的精油 |
CN102771519A (zh) * | 2011-05-13 | 2012-11-14 | 郭贵明 | 一种手机天然芳香除菌剂 |
WO2017029298A1 (en) * | 2015-08-17 | 2017-02-23 | Sanovel Ilac Sanayi Ve Ticaret A.S. | A topical antiviral composition |
CN108478761A (zh) * | 2018-05-10 | 2018-09-04 | 江苏善唯斯生物科技有限公司 | 一种淫羊藿抑菌精油 |
CN111449093A (zh) * | 2020-05-20 | 2020-07-28 | 商磊 | 一种具有抗菌消毒作用的天然精油组合物及其应用 |
CN111714543A (zh) * | 2020-05-14 | 2020-09-29 | 广州市水晶花园有机健康产业有限公司 | 一种具有杀菌功效的本草精油及其制备方法与应用 |
-
2020
- 2020-12-14 CN CN202011474411.6A patent/CN112514926B/zh active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1500477A (zh) * | 2002-11-13 | 2004-06-02 | 丛繁滋 | 带有植物芳香气息的速效气雾剂及其制备方法 |
CN1805784A (zh) * | 2003-05-11 | 2006-07-19 | 内盖夫研发局属本古里昂大学 | 胶囊化的精油 |
CN102771519A (zh) * | 2011-05-13 | 2012-11-14 | 郭贵明 | 一种手机天然芳香除菌剂 |
WO2017029298A1 (en) * | 2015-08-17 | 2017-02-23 | Sanovel Ilac Sanayi Ve Ticaret A.S. | A topical antiviral composition |
CN108478761A (zh) * | 2018-05-10 | 2018-09-04 | 江苏善唯斯生物科技有限公司 | 一种淫羊藿抑菌精油 |
CN111714543A (zh) * | 2020-05-14 | 2020-09-29 | 广州市水晶花园有机健康产业有限公司 | 一种具有杀菌功效的本草精油及其制备方法与应用 |
CN111449093A (zh) * | 2020-05-20 | 2020-07-28 | 商磊 | 一种具有抗菌消毒作用的天然精油组合物及其应用 |
Non-Patent Citations (4)
Title |
---|
Essential Oils as Antiviral Agents, Potential of Essential Oils to Treat SARS-CoV-2 Infection: An In-Silico Investigation;Joyce Kelly R. da Silva et al.;《International Journal of Molecular Sciences》;20200512;第21卷(第10期);第1-35页 * |
Geranium and Lemon Essential Oils and Their Active Compounds Downregulate Angiotensin-Converting Enzyme 2 (ACE2), a SARS-CoV-2 Spike Receptor-Binding Domain, in Epithelial Cells;K. J. Senthil Kumar et al.,;《PLANTS-BASEL》;20200630;第9卷(第6期);第1-12页 * |
Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species;Monica R.Loizzo et al.;《Chemistry & Biodiversity》;20080320;第5卷(第3期);第461-470页 * |
植物精油抗病毒研究概况;黄月红 等;《上海农业科技》;20200805(第4期);第24-26页 * |
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Effective date of registration: 20231122 Address after: Room 3704, Building 1, Gaode Land Center, Shangcheng District, Hangzhou City, Zhejiang Province, China Patentee after: Zhejiang Fushikai Biotechnology Co.,Ltd. Patentee after: ZHEJIANG University Address before: Room 406, building 3, Shidao Science Park, Gexiang village, Cangqian street, Yuhang District, Hangzhou City, Zhejiang Province Patentee before: HANGZHOU XIANGWAI ENVIRONMENTAL PROTECTION SCIENCE & TECHNOLOGY CO.,LTD. Patentee before: ZHEJIANG University |