CN112472897A - Dialyzer barrel and dialyzer with same - Google Patents

Abstract

The invention discloses a dialyzer cartridge and a dialyzer, wherein the dialyzer cartridge comprises: the utility model discloses a dialysis solution mouth, hollow barrel, the both ends open-ended lateral wall of barrel sets up the dialysate mouth, and the opening inboard sets up the sleeve, telescopic outer end outer wall and inner outer wall respectively with the inner wall sealing connection of barrel, and the dialysate mouth is just to the sleeve, and telescopic lateral wall sets up a plurality of through-holes, and the area of the through-hole that is close to the dialysate mouth is less than the area of the through-hole of keeping away from the dialysate mouth. Compared with the prior art, the cylinder structure is simpler, so that the cost of the die is lower than that of the prior design; abandon original baffle design, set up the sleeve through the both ends at the barrel, after the dislysate mouth was flowed through to the dislysate, inside the through-hole entering silk bundle by distributing on the cover barrel wall, the gas of entering can flow out along with the dislysate, can not remain in the barrel. By planning the distribution and the size of the through holes, the flow of the dialysis fluid at different positions of the cartridge can be adjusted.

Description

Dialyzer barrel and dialyzer with same

Technical Field

The invention relates to the technical field of dialysis, in particular to a dialyzer barrel. In addition, the invention also relates to a dialyzer comprising the dialyzer cartridge.

Background

Dialysis is one of the effective methods for treating end-stage renal failure. Hemodialysis (Hemodialysis), called Hemodialysis for short, is also called artificial kidney and kidney washing in popular terms, and is one of the blood purification technologies. The semi-permeable membrane principle is utilized, and the purposes of purifying blood and correcting water electrolyte and acid-base balance are achieved by dispersing and removing various harmful and redundant metabolic wastes and excessive electrolytes in the body. The hemodialyzer is called dialyzer for short, is a pipeline and a container for solute exchange between blood and dialysate, and is a key part of hemodialysis. The dialyzer consists of hollow fiber, casing, sealing layer and end cap. The dialysis membrane is made into slender hollow fiber bundle, which is placed inside transparent cylindrical casing, and the hollow fiber bundle has two sides sealed with non-toxic medical polyurethane adhesive and fixed to the casing, and has opening outside the sealing layer and outer end screwed with dome cover to form blood chamber and top opening for connecting blood pipeline. The performance of the dialyzer is related to the hollow fibers, membrane area, end caps and cartridge structure used. Through the structural design who optimizes the barrel, can improve the mobile state of dislysate in the cerini dialyser cerini, material exchange's efficiency during the improvement dialysis to promote treatment.

The structure of the barrel of the dialyzer is composed of a barrel structure which is used for placing tows and has two ends opened and flanges, and two sleeves (dialysate ports) which are respectively arranged on the flanges at the two ends of the barrel and have axes which are vertically intersected with the axis of the barrel. The flange has an inner diameter greater than the inner diameter of the middle section of the cartridge and there are structures, such as threads, near the ports for connecting the dialyzer end cap. Baffles to restrain the tows are typically provided within the flanges, and there are often grid baffles, full-circumference baffles, half-circumference or less than half-circumference baffles, and the like. The grid baffle is a circumferentially distributed baffle which is vertically or obliquely inserted into the sealing layer, and the full-circumference baffle is a circumferentially continuous baffle, a half-circumference baffle or a less-than-half-circumference baffle which is a narrower baffle arranged at the dialysate outlet.

The purpose of arranging the baffles at the whole periphery of the baffle and the dialysate opening is to avoid damage such as membrane rupture and the like caused by direct flushing of dialysate to membrane filaments; and meanwhile, the dialysate is shunted to two sides, so that the flow distribution of the dialysate is improved. In addition to the above purpose, the grid type baffle plate can also play a role in avoiding separation of the rubber shell and restraining the tows. The above design, however, introduces new problems while solving the problems. For the dialyzer adopting the small baffle design, the shunting effect of the baffle is small, and dialysate cannot uniformly permeate into the tows at the end part; for a full-circumference baffle, the baffle and the inner wall of the dialyzer flange form a groove, and gas cannot be eliminated by itself after entering the groove. For the grid type baffle, especially the oblique grid type baffle, the mold structure is complex, the manufacturing difficulty is large and the cost is high.

In summary, how to ensure that the dialysate uniformly permeates into the filament bundle, facilitate the gas discharge, and simplify the mold structure is a problem to be solved by those skilled in the art.

Disclosure of Invention

In view of the above, an object of the present invention is to provide a dialyzer shell, which uses a sleeve instead of a baffle, and under the action of a through hole, can ensure that dialysate can uniformly permeate into a bundle, and gas can be discharged along with the flow of the dialysate without remaining in the dialyzer shell, and has a simple structure, a simplified mold structure, and a reduced manufacturing cost.

It is another object of the invention to provide a dialyzer comprising the above dialyzer cartridge.

In order to achieve the above purpose, the invention provides the following technical scheme:

a dialyzer cartridge comprising: the hollow barrel, the both ends open-ended lateral wall of barrel sets up the dialysate mouth, the opening inboard sets up the sleeve, telescopic outer end outer wall and inner outer wall respectively with the inner wall sealing connection of barrel, the dialysate mouth is just right the sleeve, telescopic lateral wall sets up a plurality of through-holes, is close to the dialysate mouth the area of through-hole is less than and keeps away from the dialysate mouth the area of through-hole.

Preferably, a protrusion is arranged on one side, away from the opening, of the port of the dialysate port connected with the hollow part of the cylinder.

Preferably, the inner wall of the opening is provided with an axial mounting groove, the periphery of the sleeve is provided with a tenon which is matched and spliced with the mounting groove, the outer end face of the sleeve is provided with a first flange which is attached to the end face of the notch of the mounting groove, and the tenon is arranged towards the wall of the sleeve along the first flange.

Preferably, the through hole includes a square opening and a narrow groove-shaped opening, and the square opening is disposed outside the narrow groove-shaped opening.

Preferably, the number of the mounting grooves is four, and the mounting grooves comprise two first mounting grooves and two second mounting grooves, wherein the connecting line of the two first mounting grooves is parallel to the axis of the dialysate port, and the connecting line of the two second mounting grooves is perpendicular to the axis of the dialysate port.

Preferably, a line connecting the two second mounting grooves is not collinear with the axis of the cylinder.

Preferably, the outer periphery of the opening is provided with a double trapezoidal thread.

Preferably, cones are respectively arranged at two ends of the barrel, the diameter of the outer ends of the cones is larger than that of the inner ends of the cones, the axes of the cones are collinear with the axis of the barrel, and second flanges extending outwards in the radial direction are arranged at the outer ends of the cones.

Preferably, the inner wall of the barrel is provided with a stepped structure, and the inner end of the sleeve is attached to the stepped surface of the stepped structure.

A dialyzer comprises a shell and sealing and filling caps arranged at two ends of the shell, wherein the shell is any one of the dialyzer cylinders.

Compared with the prior art, the barrel structure is simpler, so that the mold cost is lower than that of the existing design, and particularly compared with a baffle barrel of an oblique grid, the barrel demoulding method is simple, and the barrel demoulding can be realized without a complex mold structure. In addition, the sleeve may occupy a portion of the volume of sealant, and therefore the amount of sealant used for a sealant layer of the same thickness is less than that of prior designs, thereby saving the cost of the sealing and filling operation.

The invention abandons the original baffle design, the sleeves are arranged at the two ends of the cylinder body, a cavity for dialysate to flow is formed between the sleeves and the cylinder body, the dialysate flows into the cavity after flowing through a dialysate opening, and then enters the inner part of the filament bundle through the through holes distributed on the sleeve wall, and the entered gas flows out along with the dialysate and cannot remain in the cylinder body. By planning the distribution and the size of the through holes, the flow of the dialysis fluid at different positions of the cartridge can be adjusted.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.

Figure 1 is a schematic view of a dialyzer cartridge provided by the present invention;

figure 2 is a cross-sectional view of one end of a dialyzer cartridge provided by the present invention;

figure 3 is an isometric view of a dialyzer cartridge provided by the present invention;

figure 4 is a partial cross-sectional view of a dialyzer cartridge provided by the present invention;

figure 5 is an exploded view of a dialyzer cartridge provided by the present invention;

FIG. 6 is an isometric view of a sleeve provided by the present invention;

FIG. 7 is a side view of a cartridge provided in accordance with the present invention adjacent a dialysate port;

FIG. 8 is a side view of the cartridge provided by the present invention, on the side away from the dialysate port.

In FIGS. 1-8:

1-dialysate port, 2-cone, 3-first flange, 4-cylinder, 5-double trapezoidal thread, 6-chamfer, 7-mounting groove, 8-protrusion, 9-step surface, 10-rib, 11-sleeve, 12-second flange, 13-square hole, 14-narrow groove shape hole, 15-tenon.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The core of the invention is to provide a dialyzer barrel, the dialyzer barrel uses a sleeve to replace a baffle, the dialysate can be ensured to uniformly permeate into a silk bundle under the action of a through hole, gas can be discharged along with the flow of the dialysate, the gas cannot remain in the dialyzer barrel, and the dialyzer barrel has a simple structure, can simplify the structure of a mold, and reduces the manufacturing cost.

Another core of the invention is to provide a dialyzer comprising the dialyzer cartridge described above.

Referring to fig. 1 to 8, fig. 1 is a schematic view of a dialyzer cartridge provided by the present invention; figure 2 is a cross-sectional view of one end of a dialyzer cartridge provided by the present invention; figure 3 is an isometric view of a dialyzer cartridge provided by the present invention; figure 4 is a partial cross-sectional view of a dialyzer cartridge provided by the present invention; figure 5 is an exploded view of a dialyzer cartridge provided by the present invention; FIG. 6 is an isometric view of a sleeve provided by the present invention; FIG. 7 is a side view of a cartridge provided in accordance with the present invention adjacent a dialysate port; FIG. 8 is a side view of the cartridge provided by the present invention, on the side away from the dialysate port.

A dialyzer cartridge comprising: hollow barrel 4, barrel 4's both ends open-ended lateral wall sets up dialysate mouth 1, and the opening inboard sets up sleeve 11, sleeve 11's outer end outer wall and inner outer wall respectively with barrel 4's inner wall sealing connection, and dialysate mouth 1 is just to sleeve 11, and sleeve 11's lateral wall sets up a plurality of through-holes, and the area of the through-hole that is close to dialysate mouth 1 is less than the area of the through-hole of keeping away from dialysate mouth 1.

The dialysate ports 1 are communicated with the hollow structure inside the cylinder 4, and dialysate enters from one dialysate port 1 and flows out from the other dialysate port 1 during dialysis. The outer diameters and the shapes of the dialysate port 1 and the dialysate outlet are designed according to the standard of the hansen interface, and four ribs 10 are arranged on the outer side of the dialysate port 1 to realize light weight setting on the premise of meeting the standard.

The inner wall of the dialysate port 1 has a draft angle, and the angle of the draft angle can be set between 0 and 2 degrees. The cylinder 4 is a thin-wall structure, and the wall thickness can be 1 mm-3 mm. The height of the sleeve 11 may be 1/10 to 1/3 barrel 4 lengths. Barrel 4 formula barrel 4 as an organic whole that this application provided also can adopt concatenation formula barrel 4. The middle section of the cylinder 4 allows a certain draft angle, and the parting surface is not limited to the middle surface of the cylinder 4.

During assembly, the sleeve 11 is assembled with the cylinder 4 before the tows are placed in the cylinder, then the hollow fiber membrane tows wrapped by the filament wrapping film are placed into the cylinder 4 from the end part of the cylinder 4, the inner diameter of the sleeve 11 is slightly larger than the outer diameter of the hollow fiber membrane tows, and collision of the sleeve 11 during placement of the hollow fiber membrane tows can be avoided. After the silk wrapping film is drawn out, the hollow fiber membrane tows are fluffy to a certain degree, so that the periphery of the hollow fiber membrane tows can be in contact with the inner wall of the cylinder body 4 and the inner wall of the sleeve 11.

And sintering and sealing and filling the hollow fiber membrane tow after the hollow fiber membrane tow is placed. Due to the sleeve 11, the hollow fiber membrane tows are bound in the whole barrel 4, so that the end faces of the hollow fiber membrane tows are not easy to loosen and disorder, the defects generated during sintering are reduced, and the stable posture of the hollow fiber membrane tows can be ensured in the sealing and filling process.

The sealing and filling cap is arranged at two ends of the sleeve 11 and then can be used for sealing and filling by using a sealant, the sealant is filled from the two dialysate ports 1 respectively, the sealant is centrifugally thrown at two ends by taking a line which is arranged at the middle part of the barrel 4 and is vertical to the axis of the barrel 4 as a rotating shaft, the sealant can be adhered between the barrel 4 and the sleeve 11, after the sealing and filling, because the outer wall of the inner end of the sleeve 11 is hermetically connected with the inner wall of the barrel 4, the sealant, a dialysate flowing channel is formed between the sleeve 11 and the barrel 4, and the dialysate can only permeate into tows through holes in the sleeve 11. The partly of sleeve 11 is in inserting sealed glue, can stabilize sleeve 11 in barrel 4 like this, also can improve sealed glue's intensity, avoids it to take place to glue the shell separation at the crop in-process, and simultaneously, sleeve 11 can occupy the volume of partly sealed glue to reduce sealed glue's quantity, thereby reduce the cost.

Considering that the dialysate pressure is higher near the dialysate port 1 than far from the dialysate port 1, and the dialysate flow rate in the through-hole near the dialysate port 1 is higher than the dialysate flow rate in the through-hole far from the dialysate port 1, the opening area of the through-hole far from the dialysate port 1 on the sleeve 11 is larger than the opening area of the through-hole near the dialysate port 1 to ensure the uniformity of the dialysate distribution.

Compared with the prior art, the structure of the cylinder body 4 is simpler, so that the cost of the die is lower than that of the existing design, particularly compared with the baffle cylinder body 4 with an oblique grating, the demoulding mode of the cylinder body 4 is simple, and the demoulding can be realized without a complex die structure. In addition, the sleeve 11 may occupy a portion of the volume of sealant, and therefore the amount of sealant used for a sealant layer of the same thickness is less than that of prior designs, thereby saving the cost of the sealing and potting operation.

The invention abandons the original baffle design, the sleeves 11 are arranged at the two ends of the cylinder body 4, a cavity for dialysate to flow is formed between the sleeves 11 and the cylinder body 4, the dialysate firstly enters the cavity after flowing through the dialysate port 1 and then enters the inner part of the filament bundle through the through holes distributed on the wall of the sleeve 11, and the entered gas can flow out along with the dialysate and cannot remain in the cylinder body 4. By planning the distribution and the size of the through-holes, the flow of the dialysis fluid at different positions of the cartridge 11 can be adjusted.

In addition to the above-described embodiments, it is further preferable that a protrusion 8 is provided on a side of the port, which is connected to the hollow portion of the cartridge 4, of the dialysate port 1, the side being away from the opening.

It should be noted that the dialysate port 1 communicates with the hollow portion of the cylinder 4, a port of the dialysate port 1 is arranged on the inner wall of the cylinder 4, and a protrusion 8 is arranged at a position of the port far from the opening at the end of the cylinder 4, so that the cross-sectional area of the dialysate flow is reduced, and the flow velocity of the dialysate at this position is increased to accelerate the dialysis speed.

In addition to the above embodiment, it is further preferable that the inner wall of the opening is provided with an axial mounting groove 7, the outer periphery of the sleeve 11 is provided with a tenon 15 which is inserted and matched with the mounting groove 7, the outer end surface of the sleeve 11 is provided with the first flange 3 which is attached to the notch end surface of the mounting groove 7, and the tenon 15 is arranged along the first flange 3 toward the cylinder wall of the sleeve 11.

It should be noted that the bottom of the tenon 15 and the upper side line of the mounting groove 7 are both provided with chamfers 6, which facilitates the positioning between the tenons 15 and the grooves. After the tenon 15 is inserted into the mounting groove 7, the outer end face of the groove is a step face arranged on the inner wall of the cylinder 4, and after the tenon 15 is mounted into the mounting groove 7, the first flange 3 is attached to the periphery of the end face of the notch, namely the step face, so as to position the sleeve 11. The sleeve 11 and the barrel 4 are fixed in a tenon 15-groove connection mode, so that the installation is convenient, other fasteners are not needed, and the structure can be simplified. Of course, the connection between the barrel 4 and the sleeve 11 may take other forms including, but not limited to, adhesive, welding, snap-fit connection, etc.

In addition to the above embodiment, it is further preferable that the through hole includes a square opening 13 and a narrow groove-shaped opening 14, and the square opening 13 is disposed outside the narrow groove-shaped opening 14.

It should be noted that, during filling, the sealant enters the barrel 4 through the dialysate port 1, and the square opening 13 on the upper part of the sleeve 11 ensures that the sealant can flow to each corner of the sleeve 11 and the end of the barrel 4. The square opening 13 is located between the lower side of the first flange 3 and the middle plane (perpendicular to the axis) of the sleeve 11. The narrow slot-shaped openings 14 are distributed unevenly below the mid-plane of the sleeve 11, with the distribution being characterized by an opening area that gradually increases from the end near the dialysate port 1 to the end remote from the dialysate port 1. The bottom of the sleeve 11 is not perforated one sixth of the height of the sleeve 11. This embodiment takes the form of a slot-shaped opening 14, although other shapes may be used, including but not limited to circular, parallelogram.

On the basis of the above embodiment, as a further preference, the number of the mounting grooves 7 is four, and the mounting grooves include two first mounting grooves and two second mounting grooves, wherein the connecting line of the two first mounting grooves is parallel to the axis of the dialysate port 1, and the connecting line of the two second mounting grooves is perpendicular to the axis of the dialysate port 1.

It should be noted that, correspondingly, the number of the tenons 15 is four, and the number of the tenons 15 corresponds to the number of the mounting grooves 7 one by one, by providing the four mounting grooves 7, when the sleeve is mounted, two first mounting grooves are aligned to the two tenons 15, and two second mounting grooves are aligned to the two tenons 15 and inserted, so that the sleeve 11 is stably mounted, the sleeve 11 is prevented from rotating, and the positioning effect of the sleeve 11 is improved.

On the basis of the above embodiment, as a further preference, the line connecting the two second mounting grooves is not collinear with the axis of the cylinder 4.

It should be noted that the mounting grooves 7 are distributed unevenly and symmetrically, that is, the connecting line of the two first mounting grooves is located on the plane where the axis of the dialysate port 1 intersects with the axis of the cylinder 4, the connecting line of the two second mounting grooves is located on the plane which is perpendicular to the axis of the dialysate port 1 and is farther away from or closer to the dialysate port 1, and the four mounting grooves 7 are unevenly distributed on the inner wall of the cylinder 4, so that the sleeve 11 can be mounted on the inner wall of the cylinder 4 only in a specified direction, and the position of the narrow groove-shaped through holes is prevented from being disordered after the sleeve 11 is mounted.

On the basis of the above embodiment, it is further preferable that the outer periphery of the opening is provided with double-line trapezoidal threads 5.

It should be noted that the peripheries of the two openings are provided with double trapezoidal threads to connect the sealing and filling cap or the dialyzer end cover. Typically this location may be provided by other structures such as bosses used for ultrasonic welding, or flanges used for snap-fit connections, etc.

On the basis of the above embodiment, it is further preferable that the two ends of the cylinder 4 are respectively provided with the cones 2, the diameter of the outer ends of the cones 2 is larger than that of the inner ends of the cones 2, the axis of the cones 2 is collinear with the axis of the cylinder 4, and the outer ends of the cones 2 are provided with the second flanges 12 extending radially outwards.

It should be noted that a slit can be formed between the outer wall of the sleeve 11 and the conical surface structure of the dialyzer for the flow of dialysate, the second flange 12 is disposed between the thread and the vertebral body, and the second flange 12 is used as a technical structure for positioning the matching clamp during the assembly process. The outer surface of the end of the cylinder 4 may not be a conical surface, but may be in the form of a stepped shaft.

In addition to the above embodiments, it is further preferable that the inner wall of the cylindrical body 4 is provided with a stepped structure, and the inner end of the sleeve 11 is attached to the stepped surface 9 of the stepped structure.

It should be noted that the lower plane of the flange at the upper end of the sleeve 11 can be in contact with the stepped plane at the end of the dialyzer barrel for axial positioning when the sleeve 11 is mounted. A section of stepped wall surface parallel to the middle section shaft of the barrel 4 is arranged in the cone surface of the end part of the dialyzer, and the inner diameter of the wall surface is the same as the outer diameter of the lower part of the sleeve 11. When the sleeve 11 is fitted into the barrel 4, these two surfaces can be engaged with each other, so that a relatively closed space is formed between the tapered surface of the barrel 4 and the sleeve 11.

Except above-mentioned cerini dialyser cerini barrel, this application still provides a cerini dialyser cerini, including the casing and set up in the cap is irritated in the sealing at casing both ends, the casing is the public cerini dialyser cerini barrel of above-mentioned arbitrary one embodiment. The structure of other parts of the dialyzer is referred to the prior art, and is not described herein again.

The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.

The dialyzer cartridge and the dialyzer provided by the present invention are described in detail above. The principles and embodiments of the present invention are explained herein using specific examples, which are presented only to assist in understanding the method and its core concepts. It should be noted that, for those skilled in the art, it is possible to make various improvements and modifications to the present invention without departing from the principle of the present invention, and those improvements and modifications also fall within the scope of the claims of the present invention.

Claims (10)

1. A dialyzer cartridge, comprising: hollow barrel (4), the both ends open-ended lateral wall of barrel (4) sets up dialysate mouth (1), the opening inboard sets up sleeve (11), the outer end outer wall and the inner outer wall of sleeve (11) respectively with the inner wall sealing connection of barrel (4), dialysate mouth (1) is just right sleeve (11), the lateral wall of sleeve (11) sets up a plurality of through-holes, is close to dialysate mouth (1) the area of through-hole is less than keeps away from dialysate mouth (1) the area of through-hole.

2. Dialyzer cartridge according to claim 1, characterized in that the port of the dialysate port (1) which is connected to the hollow part of the cartridge (4) is provided with a projection (8) on the side remote from the opening.

3. The dialyzer cartridge of claim 1, wherein the inner wall of the opening is provided with an axial mounting groove (7), the outer circumference of the sleeve (11) is provided with a tenon (15) which is matched and inserted with the mounting groove (7), the outer end face of the sleeve (11) is provided with a first flange (3) which is attached to the notch end face of the mounting groove (7), and the tenon (15) is arranged along the first flange (3) to the wall of the sleeve (11).

4. The dialyzer cartridge of claim 3, wherein the through holes comprise square openings (13) and slot-shaped openings (14), the square openings (13) being disposed outside the slot-shaped openings (14).

5. A dialyzer cartridge according to claim 3, characterized in that the number of the mounting grooves (7) is four, comprising two first mounting grooves and two second mounting grooves, the line connecting the two first mounting grooves being parallel to the axis of the dialysate port (1) and the line connecting the two second mounting grooves being perpendicular to the axis of the dialysate port (1).

6. Dialyzer cartridge of claim 4, characterized in that the line connecting the two second mounting grooves is not collinear with the axis of the cartridge (4).

7. Dialyzer cartridge according to claim 1, characterized in that the outer circumference of the opening is provided with a double trapezoidal thread (5).

8. A dialyzer cartridge according to any of claims 1 to 7, characterized in that a cone (2) is provided at each end of the cartridge (4), the outer end diameter of the cone (2) being larger than the inner end diameter of the cone (2), the axis of the cone (2) being collinear with the axis of the cartridge (4), the outer end of the cone (2) being provided with a second flange (12) extending radially outwards.

9. Dialyzer cartridge of claim 8, characterized in that the inner wall of the cartridge (4) is provided with a stepped structure, the inner end of the sleeve (11) fitting against a stepped surface (9) of the stepped structure.

10. A dialyzer comprising a housing and filling caps provided at both ends of the housing, wherein the housing is the dialyzer shell of any one of claims 1 to 9.

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