CN112449602A - 超高剂量率辐射和治疗剂的使用方法 - Google Patents
超高剂量率辐射和治疗剂的使用方法 Download PDFInfo
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- CN112449602A CN112449602A CN201980048106.XA CN201980048106A CN112449602A CN 112449602 A CN112449602 A CN 112449602A CN 201980048106 A CN201980048106 A CN 201980048106A CN 112449602 A CN112449602 A CN 112449602A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
- A61N5/1031—Treatment planning systems using a specific method of dose optimization
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1077—Beam delivery systems
- A61N5/1084—Beam delivery systems for delivering multiple intersecting beams at the same time, e.g. gamma knives
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Primary Health Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Data Mining & Analysis (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Radiology & Medical Imaging (AREA)
- Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Databases & Information Systems (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201862700783P | 2018-07-19 | 2018-07-19 | |
US62/700,783 | 2018-07-19 | ||
PCT/US2019/042603 WO2020018904A1 (fr) | 2018-07-19 | 2019-07-19 | Méthodes d'utilisation de rayonnement à débit de dose ultra élevé et d'agents thérapeutiques |
Publications (1)
Publication Number | Publication Date |
---|---|
CN112449602A true CN112449602A (zh) | 2021-03-05 |
Family
ID=67515191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201980048106.XA Pending CN112449602A (zh) | 2018-07-19 | 2019-07-19 | 超高剂量率辐射和治疗剂的使用方法 |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3823618A1 (fr) |
CN (1) | CN112449602A (fr) |
WO (1) | WO2020018904A1 (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9855445B2 (en) | 2016-04-01 | 2018-01-02 | Varian Medical Systems, Inc. | Radiation therapy systems and methods for delivering doses to a target volume |
US10183179B1 (en) | 2017-07-21 | 2019-01-22 | Varian Medical Systems, Inc. | Triggered treatment systems and methods |
US11590364B2 (en) | 2017-07-21 | 2023-02-28 | Varian Medical Systems International Ag | Material inserts for radiation therapy |
US11712579B2 (en) | 2017-07-21 | 2023-08-01 | Varian Medical Systems, Inc. | Range compensators for radiation therapy |
US10092774B1 (en) | 2017-07-21 | 2018-10-09 | Varian Medical Systems International, AG | Dose aspects of radiation therapy planning and treatment |
CN111479571A (zh) | 2017-07-21 | 2020-07-31 | 瓦里安医疗系统公司 | 超高剂量率辐射和治疗剂的使用方法 |
US10549117B2 (en) | 2017-07-21 | 2020-02-04 | Varian Medical Systems, Inc | Geometric aspects of radiation therapy planning and treatment |
US10843011B2 (en) | 2017-07-21 | 2020-11-24 | Varian Medical Systems, Inc. | Particle beam gun control systems and methods |
EP3967367A1 (fr) | 2017-11-16 | 2022-03-16 | Varian Medical Systems Inc | Sortie de faisceau améliorée et mise en forme de champ dynamique destinés à un système de radiothérapie |
US10910188B2 (en) | 2018-07-25 | 2021-02-02 | Varian Medical Systems, Inc. | Radiation anode target systems and methods |
US11116995B2 (en) | 2019-03-06 | 2021-09-14 | Varian Medical Systems, Inc. | Radiation treatment planning based on dose rate |
US10814144B2 (en) | 2019-03-06 | 2020-10-27 | Varian Medical Systems, Inc. | Radiation treatment based on dose rate |
US11103727B2 (en) | 2019-03-08 | 2021-08-31 | Varian Medical Systems International Ag | Model based PBS optimization for flash therapy treatment planning and oncology information system |
US11090508B2 (en) | 2019-03-08 | 2021-08-17 | Varian Medical Systems Particle Therapy Gmbh & Co. Kg | System and method for biological treatment planning and decision support |
US10918886B2 (en) | 2019-06-10 | 2021-02-16 | Varian Medical Systems, Inc. | Flash therapy treatment planning and oncology information system having dose rate prescription and dose rate mapping |
US11291859B2 (en) | 2019-10-03 | 2022-04-05 | Varian Medical Systems, Inc. | Radiation treatment planning for delivering high dose rates to spots in a target |
US11865361B2 (en) | 2020-04-03 | 2024-01-09 | Varian Medical Systems, Inc. | System and method for scanning pattern optimization for flash therapy treatment planning |
US11541252B2 (en) * | 2020-06-23 | 2023-01-03 | Varian Medical Systems, Inc. | Defining dose rate for pencil beam scanning |
US20240009483A1 (en) * | 2020-06-26 | 2024-01-11 | Cancer Research Technology Limited | Treatment Planning System |
US11957934B2 (en) | 2020-07-01 | 2024-04-16 | Siemens Healthineers International Ag | Methods and systems using modeling of crystalline materials for spot placement for radiation therapy |
EP4112123A1 (fr) * | 2021-07-02 | 2023-01-04 | RaySearch Laboratories AB | Planification et optimisation de thérapie à multimodalité |
US20240091559A1 (en) * | 2022-09-21 | 2024-03-21 | Siemens Healthineers International Ag | Enhanced dose rate/ultra-high dose rate radiation and spatially fractioned radiation therapy |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101927065A (zh) * | 2009-01-16 | 2010-12-29 | 北卡罗来纳大学查珀尔希尔分校 | 用于癌症治疗和研究的紧凑型微束放疗系统及方法 |
US20130274233A1 (en) * | 2012-04-03 | 2013-10-17 | President And Fellow Of Harvard College | Modulators of hedgehog signaling pathway |
US20150011817A1 (en) * | 2013-07-03 | 2015-01-08 | Yuxin Feng | System and Method for Delivering an Ultra-High Dose of Radiation Therapy |
CN105209070A (zh) * | 2013-03-15 | 2015-12-30 | 瓦里安医疗系统公司 | 用于放射疗法的生物标志物 |
US9636525B1 (en) * | 2011-02-15 | 2017-05-02 | Velayudhan Sahadevan | Method of image guided intraoperative simultaneous several ports microbeam radiation therapy with microfocus X-ray tubes |
CN111479571A (zh) * | 2017-07-21 | 2020-07-31 | 瓦里安医疗系统公司 | 超高剂量率辐射和治疗剂的使用方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006039569A1 (fr) * | 2004-09-30 | 2006-04-13 | The University Of Chicago | Polytherapie d'inhibiteurs hedgehog, de rayonnement et d'agents chimiotherapeutiques |
TW200948380A (en) | 2008-04-11 | 2009-12-01 | Galaxy Biotech Llc | Combination of HGF inhibitor and PTEN agonist to treat cancer |
US7801270B2 (en) | 2008-06-19 | 2010-09-21 | Varian Medical Systems International Ag | Treatment plan optimization method for radiation therapy |
CN105358217A (zh) * | 2013-06-18 | 2016-02-24 | 杜克大学 | 在特定治疗标准及特定治疗参数下用于特定患者放射治疗计划的系统和方法 |
US10080911B2 (en) * | 2015-09-10 | 2018-09-25 | Varian Medical Systems, Inc. | Knowledge-based spatial dose metrics and methods to generate beam orientations in radiotherapy |
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2019
- 2019-07-19 EP EP19749118.6A patent/EP3823618A1/fr active Pending
- 2019-07-19 WO PCT/US2019/042603 patent/WO2020018904A1/fr active Application Filing
- 2019-07-19 CN CN201980048106.XA patent/CN112449602A/zh active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101927065A (zh) * | 2009-01-16 | 2010-12-29 | 北卡罗来纳大学查珀尔希尔分校 | 用于癌症治疗和研究的紧凑型微束放疗系统及方法 |
US9636525B1 (en) * | 2011-02-15 | 2017-05-02 | Velayudhan Sahadevan | Method of image guided intraoperative simultaneous several ports microbeam radiation therapy with microfocus X-ray tubes |
US20130274233A1 (en) * | 2012-04-03 | 2013-10-17 | President And Fellow Of Harvard College | Modulators of hedgehog signaling pathway |
CN105209070A (zh) * | 2013-03-15 | 2015-12-30 | 瓦里安医疗系统公司 | 用于放射疗法的生物标志物 |
US20150011817A1 (en) * | 2013-07-03 | 2015-01-08 | Yuxin Feng | System and Method for Delivering an Ultra-High Dose of Radiation Therapy |
CN111479571A (zh) * | 2017-07-21 | 2020-07-31 | 瓦里安医疗系统公司 | 超高剂量率辐射和治疗剂的使用方法 |
Non-Patent Citations (3)
Title |
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DANIEL E.等: "Long-term Survival and Toxicity in Patients Treated With High-Dose Intensity Modulated Radiation Therapy for Localized Prostate Cancer" * |
S. TECKIE等: "Ultra-high-dose Stereotactic Body Radiation Therapy (SBRT) is Feasible for Tumors in the Head and Neck (HN)" * |
VINCENT FAVAUDON等: "Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice" * |
Also Published As
Publication number | Publication date |
---|---|
EP3823618A1 (fr) | 2021-05-26 |
WO2020018904A1 (fr) | 2020-01-23 |
WO2020018904A9 (fr) | 2020-04-16 |
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