CN112441297A

CN112441297A - Filling machine for producing Chinese herbal medicine toothpaste

Info

Publication number: CN112441297A
Application number: CN202011326786.8A
Authority: CN
Inventors: 罗超; 李伟; 朱君
Original assignee: Shanghai University of Medicine and Health Sciences
Current assignee: Shanghai University of Medicine and Health Sciences
Priority date: 2020-11-24
Filing date: 2020-11-24
Publication date: 2021-03-05

Abstract

The invention discloses a filling machine for producing Chinese herbal medicine toothpaste, which comprises a machine body, a filling cylinder, a filling part and a disinfection mechanism communicated with the filling cylinder; the machine body comprises a supporting rod and a base; the disinfection mechanism is fixedly arranged in the base; the filling cylinder is fixedly connected with the supporting rod and is vertically arranged above the filling part; the filling barrel comprises a barrel body, a barrel cover, a driving motor, a lead screw, a stirring rod and a cleaning device; the driving motor is arranged on the top surface of the cylinder cover, the output end of the driving motor is in transmission connection with one end of the lead screw, and the other end of the lead screw penetrates through the cylinder cover and extends into the inner cavity of the cylinder body; the screw rod is in threaded connection with the stirring rod and is arranged in the inner cavity of the cylinder body; the bottom end of the stirring rod is detachably connected with a cleaning device; the bottom of the cylinder body is provided with a through hole which is arranged corresponding to the filling pipeline of the filling part. The invention ensures that the filling machine body is cleaned and disinfected by optimizing the stirring device and matching with the unique cleaning device and the unique disinfecting device, so that the stirring efficiency is higher and the service life of the machine is longer.

Description

Filling machine for producing Chinese herbal medicine toothpaste

Technical Field

The invention relates to the technical field, in particular to a filling machine for producing Chinese herbal medicine toothpaste.

Background

At present, the popularization rate of national toothpaste purchase reaches a higher level, the toothpaste is integrated into the daily life of people, the stable life expenditure of residents in China becomes, along with the improvement of the living standard of people and the promotion and guidance of strengthening the tooth cleaning of love teeth, the demand of the domestic market for the toothpaste is steadily increased, and the market scale of the national toothpaste reaches 243 hundred million yuan in 2016. In recent years, the toothpaste industry in China improves a standard system and increases innovation strength by implementing a production license system, so that the safety of products is greatly improved, the quality and the efficacy reach higher levels, and the competitiveness is increasingly enhanced. The toothpaste industry in China has been transited from a full competition stage to a monopoly competition stage, and different development modes such as differentiated management, brand cultivation and the like appear. The toothpaste belongs to the daily chemical industry in the light industry, is the industry for producing daily necessary consumer goods for cleaning teeth and protecting oral hygiene, and has the main products: toothpaste, toothbrush, dental floss, mouthwash, mouth cleaning mist, denture cleanser, and the like. At present, the domestic toothpaste industry is monopolized by large brands and is full of all brands, and the national product brand is singly listed as a champion brand, and is shuffled again to the current domestic brand to be reintegrated and seek a breakthrough stage. At present, toothpaste enterprises are classified into three categories: foreign enterprises, domestic large-scale toothpaste enterprises and domestic small-scale toothpaste enterprises. At present, the domestic toothpaste market is strong in foreign resources and weak in local resources, foreign resource brands such as Gaolu, Jiajieshi, black people and the like account for more than seven-element market shares, while the local brands such as Yunnan white drug powder, cloquine, black sister and the like only account for less than three-element market shares. The domestic toothpaste brand avoids the positive conflict with the foreign brand, and occupies the market segments such as Chinese herbal medicine toothpaste, oral care for the middle-aged and the elderly, and the like.

The selenium/Chinese herbal medicine toothpaste rich in selenium and bletilla striata is developed and produced. The bletilla striata is dispersed into a nano powder material by a nano dispersion technology, and the nano powder material has the functions of diminishing inflammation, stopping bleeding, repairing dental ulcer, whitening and strengthening teeth, and simultaneously has good prevention and treatment effects on oral and dental diseases such as sore throat, periodontitis, gingivitis, caries prevention, oral odor and the like. Fully mixing inorganic selenium and nano bletilla striata powder by an organic-inorganic composite technology, realizing efficient biological utilization of selenium by organizing the inorganic selenium, and simultaneously reducing the biological toxicity of the inorganic selenium.

Most of the existing toothpaste filling machines are simple in structure, paste cannot be uniformly mixed, and after the toothpaste filling machines are used for a long time, the cleaning effect in the machines is poor, and Chinese herbal medicine toothpaste has viscosity and can be adhered in the filling machines to cause the problems of blockage and the like.

Therefore, a filling machine aiming at the characteristics of the Chinese herbal medicine toothpaste is urgently needed.

Disclosure of Invention

The invention aims to provide a filling machine for producing Chinese herbal medicine toothpaste, which is used for solving the problems in the prior art, and can realize cleaning and disinfection of a machine body, so that the stirring efficiency is higher, and the service life of the machine is longer.

In order to achieve the purpose, the invention provides the following scheme: the invention provides a filling machine for producing Chinese herbal medicine toothpaste, which comprises a machine body, a filling cylinder, a filling part and a disinfection mechanism communicated with the filling cylinder; the machine body comprises a supporting rod and a base for inserting the supporting rod; the disinfection mechanism is fixedly arranged in the base; the filling part is arranged on the top surface of the base;

the filling cylinder is fixedly connected with the supporting rod, and the filling cylinder is vertically arranged above the filling part; the filling cylinder comprises a cylinder body, a cylinder cover, a driving motor, a lead screw, a stirring rod and a cleaning device; the bottom surface of the barrel cover is provided with an inner edge, and the barrel cover is buckled with the barrel body through the inner edge; the driving motor is arranged on the top surface of the cylinder cover, the output end of the driving motor is in transmission connection with one end of the lead screw, and the other end of the lead screw penetrates through the cylinder cover and extends into the inner cavity of the cylinder body; the screw rod is in threaded connection with the stirring rod and is arranged in the inner cavity of the cylinder body; the bottom end of the stirring rod is detachably connected with a cleaning device; the bottom of the cylinder body is provided with a through hole, and the through hole is arranged corresponding to the filling pipeline of the filling part.

The stirring rod is of a bent pipe structure, and a plurality of stirring rods are arranged at equal intervals along the circumference; the bottom of puddler is equipped with the screw thread, cleaning device's connecting rod one end cup joints mutually and passes through the thread tightening with the bottom of puddler.

The cleaning device also comprises an elastic rod and a cleaning block; one end of the elastic rod is provided with a sliding chute, a plurality of clamping points are filled in the sliding chute, and the other end of the connecting rod is limited in the sliding chute and slides among the clamping points; the other end of the elastic rod is fixedly connected with the cleaning block.

Preferably, the relative position of the elastic rod and the connecting rod is changed through the clamping point adjustment, so that the position of the cleaning block is adjusted, the inner wall of the cylinder body can be cleaned at a full angle, and the cleaning effect is good.

Furthermore, when cleaning, the interior of the device can be cleaned only by normal operation after the cleaning device is installed, manual operation is not needed, time and labor are saved, and the defects of the existing paste filling machine are overcome.

A filter screen layer is also arranged in the cylinder body; the bottom of the cylinder body is of a funnel-shaped structure, and the bottom surface of the cylinder body is provided with the through hole; the peripheral wall of the bottom end of the lead screw is provided with an annular groove; the annular groove corresponds to the bottom of the cylinder body in position; the filter screen layer is of a ring body structure, the outer ring of the filter screen layer is limited in the small-caliber end of the cylinder body, and the inner ring of the filter screen layer is limited in the annular groove.

Preferably, the filter screen layer can slide on the bottom surface of the cylinder body, so that the Chinese herbal medicine toothpaste is prevented from being coagulated into particles and filling is finished; the filter screen layer rotates up and down in a certain space along with the screw rod to enlarge the contact area, and the paste bodies are further mixed.

The bottom surface of the cylinder cover is also provided with a lantern ring; the lantern ring is sleeved with the lead screw; and a threaded sleeve is arranged in the lantern ring.

Furthermore, the drive motor drives the lead screw to rotate during stirring, the lead screw rotates and descends under the drive of the threaded sleeve in the lantern ring, so that the stirring rod is driven to rotate and descend for stirring, and the stirring rod can ascend by reversing the motor.

The filling part also comprises a filling cylinder and a piston; the filling cylinder is in transmission connection with one end of the piston; the other end of the piston is communicated with the filling pipeline.

The bottom surface of the filling pipeline is provided with an opening and is communicated with the through hole of the cylinder body through the opening; and a detachable sealing sleeve is arranged at the communication position of the opening and the through hole.

The disinfection mechanism comprises a water tank and a steam outlet pipeline; one end of the steam outlet pipeline is communicated with the top side of the water tank, and the other end of the steam outlet pipeline extends out of the base and is communicated with the cylinder cover.

A heating pipe and a heating box are arranged in the water tank; one end of the heating box is electrically connected with an external power supply, and the heating pipe is installed at the other end of the heating box.

And a pressure gauge is further installed on one side of the water tank.

Preferably, steam generated after heating in the water tank is sprayed into the cylinder body through the steam outlet pipeline for sterilization; the disinfection mechanism installed at the bottom adopts high-temperature water vapor to disinfect, so that the disinfection mechanism is not only efficient and rapid, but also achieves the purposes of further cleaning and disinfection by the water vapor, greatly improves the disinfection efficiency and saves manpower.

The Chinese herbal medicine toothpaste selected by the application contains selenium which is a trace element and a recognized stomach nourishing element, is a natural antioxidant, can effectively inhibit the generation of active oxygen, clear HP, prevent stomach mucosa necrosis, and promote the repair of mucosa and the healing of ulcer. Can repair gastric mucosa and prevent gastric mucosa canceration. It is also well documented in the medical literature that selenium controls the inflammatory action of H.pylori on the stomach and inhibits its proliferation. Therefore, products such as maltsivie tablets and the like can be used for carrying out targeted bacteriostasis and stomach nourishing when helicobacter pylori is infected.

After the HP acts on the selenium with a certain concentration, the number of HP bacterial colonies is reduced along with the increase of the selenium concentration, the color of the bacterial colonies is changed from grey white to brick red, the hemolysis phenomenon gradually disappears along with the increase of the selenium concentration and the prolonging of the acting time, the shape of the HP is changed from a bending shape to a spherical shape or an elliptical shape, and flagella and pili are shed; selenium has no influence or no obvious influence on the activities of urease, catalase and alkaline phosphatase; selenium with a certain concentration can enable pET32a-vacA-E.coliBL21 engineering bacteria expressing VacA to generate fat-soluble brick red pigment, and the color is deepened along with the increase of the selenium concentration; selenium with a certain concentration reduces the expression quantity of recombinant VacA by inhibiting the growth of pET32a-vacA-E.coliBL21 engineering bacteria, but does not influence the vacuolating virus activity and the coding gene sequence; selenium can enhance the inhibition effect of the recombinant VacA on gastric cancer cells, so that the cell division index and the colony formation rate are reduced, the number of S-phase cells is reduced, and the total number of G1-phase cells is increased; the purified VacA recombinant protein can be recognized by a VacA antibody and has good antigenicity. The animal experiment results show that: helicobacter pylori of a certain concentration can induce the inflammation and precancerous lesion of mouse gastric mucosa tissue, and the ratio of CD4/CD8 in the blood of the mouse is reduced; selenium with certain concentration has protective effect on gastric mucosa injury caused by helicobacter pylori infection, and can enhance CD4 cell activity and increase CD4/CD8 ratio. The clinical specimen research result shows that: in a series of gastric mucosal lesions, a P16 expression HP positive specimen is obviously lower than an HP negative specimen (P is less than 0.01 ═ and CD44V6, C-met and PCNA expression HP positive specimen are all obviously higher than that of a negative specimen (P is less than 0.01 ═ and P16 expression is negatively related to CD44V6, C-met and PCNA expression in HP-infected gastric mucosal lesion tissues (rs is-0.6971 and P is less than 0.01; rs is-0.4811 and P is less than 0.01; rs is-0.6075 and P is less than 0.01), CD44V6 expression is positively related to C-met and PCNA expression (rs is 0.6450 and P is less than 0.01; rs is 0.4977 and P is less than 0.01), the selenium content in HP-infected gastric mucosal tissues is obviously increased and relatively decreased along with the lesion degree of gastric mucosa lesion, but is higher than that in normal tissues, the selenium content is respectively related to helicobacter pylori 7344 and C-734, and the positive growth rate of pyloric bulb is more positive than 0.05, the invasiveness is weakened, and the pathogenicity is reduced; selenium with a certain concentration can enable escherichia coli expressing recombinant VacA to generate fat-soluble brick red pigment, and the pigment generation amount is increased along with the increase of the selenium concentration; selenium can reduce the expression quantity of the recombinant VacA of helicobacter pylori, but does not influence the cell vacuolation virus activity and the coding gene sequence; selenium with a certain concentration has a protection effect on mouse gastric mucosa lesion induced by helicobacter pylori infection, improves organism cellular immunity and humoral immunity by enhancing CD4 cell activity, and inhibits the down regulation of CD4/CD8 ratio caused by helicobacter pylori infection; HP infection can promote the expression of coding genes of CD44V6, C-met and PCNA of gastric mucosal lesion tissues and inhibit the expression of coding genes of P16; selenium can directly or indirectly inhibit the expression of CD44V6, PCNA and C-met coding genes, promote the expression of P16 coding gene and antagonize the regulation effect of helicobacter pylori on the protein; the selenium content of the pathological tissues of the gastric mucosa infected by the helicobacter pylori is obviously increased and is relatively reduced along with the progressive pathological degree of the gastric mucosa, but is higher than that of normal tissues.

In conclusion, the organic-inorganic composite technology is adopted to fully mix inorganic selenium and nano bletilla striata powder, and the high-efficiency biological utilization of selenium is realized through the organization of the inorganic selenium, and the biological toxicity of the inorganic selenium is reduced.

The invention discloses the following technical effects: the invention ensures that the filling machine body is cleaned and disinfected by optimizing the stirring device and matching with the unique cleaning device and the unique disinfecting device, so that the stirring efficiency is higher and the service life of the machine is longer.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without inventive exercise.

Fig. 1 is a schematic view of the overall structure of the present invention.

Fig. 2 is a schematic view of the disinfection mechanism of the present invention.

The device comprises a machine body 1, a filling cylinder 2, a disinfection mechanism 4, a support rod 11, a base 12, a cylinder body 21, a cylinder cover 22, a driving motor 23, a lead screw 24, a stirring rod 25, a lantern ring 26, a filter screen layer 27, a filling pipeline 31, a filling cylinder 32, a piston 33, a water tank 41, a steam outlet pipeline 42, a heating pipe 43, a heating box 44, a pressure gauge 45, a connecting rod 51, an elastic rod 52 and a cleaning block 53.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.

The invention provides a filling machine for producing Chinese herbal medicine toothpaste, which comprises a machine body 1, a filling cylinder 2, a filling part and a disinfection mechanism 4 communicated with the filling cylinder 2; the machine body 1 comprises a supporting rod 11 and a base 12 for inserting the supporting rod 11; the disinfection mechanism 4 is fixedly arranged in the base 12; the filling part is arranged on the top surface of the base 12;

the filling cylinder 2 is fixedly connected with the support rod 11, and the filling cylinder 2 is vertically arranged above the filling part; the charging barrel 2 comprises a barrel body 21, a barrel cover 22, a driving motor 23, a lead screw 24, a stirring rod 25 and a cleaning device; the bottom surface of the cylinder cover 22 is provided with an inner edge and is buckled with the cylinder body 21 through the inner edge; the driving motor 23 is installed on the top surface of the cylinder cover 22, the output end of the driving motor 23 is in transmission connection with one end of the screw rod 24, and the other end of the screw rod 24 penetrates through the cylinder cover 22 and extends into the inner cavity of the cylinder body 21; the screw rod 24 is in threaded connection with the stirring rod 25 and is arranged in the inner cavity of the cylinder body 21; the bottom end of the stirring rod 25 is detachably connected with a cleaning device; the bottom of the barrel body 21 is provided with a through hole, and the through hole is arranged corresponding to the filling pipeline 31 of the filling part.

The stirring rod 25 is of a bent pipe structure and is arranged at equal intervals along the circumference; the bottom of puddler 25 is equipped with the screw thread, and connecting rod 51 one end of cleaning device cup joints mutually and passes through the thread tightening with the bottom of puddler 25.

The cleaning device further comprises a resilient bar 52 and a cleaning block 53; one end of the elastic rod 52 is provided with a sliding chute which is filled with a plurality of clamping points, and the other end of the connecting rod 51 is limited in the sliding chute and slides between the clamping points; the other end of the elastic rod 52 is fixedly connected with a cleaning block 53.

A filter screen layer 27 is also arranged in the cylinder body 21; the bottom of the cylinder body 21 is of a funnel-shaped structure, and the bottom surface is a through hole; the circumferential wall of the bottom end of the screw rod 24 is provided with an annular groove; the annular groove corresponds to the bottom of the cylinder body 21; the filter screen layer 27 is a ring structure, the outer ring of the filter screen layer 27 is limited in the small-caliber end of the cylinder body 21, and the inner ring of the filter screen layer 27 is limited in the annular groove.

The bottom surface of the cylinder cover 22 is also provided with a lantern ring 26; the lantern ring 26 is sleeved with the lead screw 24; a threaded sleeve is mounted within the collar 26.

The filling part also comprises a filling cylinder 32 and a piston 33; the filling cylinder 32 is in transmission connection with one end of a piston 33; the other end of the piston 33 is in communication with the filling duct 31.

The bottom surface of the filling pipeline 31 is provided with an opening and is communicated with the through hole of the cylinder body 21 through the opening; and a detachable sealing sleeve is arranged at the communication position of the opening and the through hole.

The disinfection mechanism 4 comprises a water tank 41 and a steam outlet pipeline 42; one end of the steam outlet pipeline 42 is communicated with the top side of the water tank 41, and the other end extends out of the base 12 and is communicated with the cylinder cover 22.

A heating pipe 43 and a heating box 44 are arranged in the water tank 41; one end of the heating box 44 is electrically connected to an external power source, and the other end is provided with a heating pipe 43.

A pressure gauge 45 is also mounted on one side of the water tank 41.

In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, are merely for convenience of description of the present invention, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.

The above-described embodiments are merely illustrative of the preferred embodiments of the present invention, and do not limit the scope of the present invention, and various modifications and improvements of the technical solutions of the present invention can be made by those skilled in the art without departing from the spirit of the present invention, and the technical solutions of the present invention are within the scope of the present invention defined by the claims.

Claims

1. A liquid filling machine of production chinese herbal medicine toothpaste which characterized in that includes: the device comprises a machine body (1), a filling cylinder (2), a filling part and a disinfection mechanism (4) communicated with the filling cylinder (2); the machine body (1) comprises a supporting rod (11) and a base (12) for inserting the supporting rod (11); the disinfection mechanism (4) is fixedly arranged in the base (12); the filling part is arranged on the top surface of the base (12);

the charging barrel (2) is fixedly connected with the supporting rod (11), and the charging barrel (2) is vertically arranged above the filling part; the charging barrel (2) comprises a barrel body (21), a barrel cover (22), a driving motor (23), a lead screw (24), a stirring rod (25) and a cleaning device; the bottom surface of the barrel cover (22) is provided with an inner edge, and the barrel cover is buckled with the barrel body (21) through the inner edge; the driving motor (23) is mounted on the top surface of the cylinder cover (22), the output end of the driving motor (23) is in transmission connection with one end of the lead screw (24), and the other end of the lead screw (24) penetrates through the cylinder cover (22) and extends into the inner cavity of the cylinder body (21); the screw rod (24) is in threaded connection with the stirring rod (25) and is arranged in the inner cavity of the cylinder body (21); the bottom end of the stirring rod (25) is detachably connected with the cleaning device; the bottom of the cylinder body (21) is provided with a through hole, and the through hole is arranged corresponding to the filling pipeline (31) of the filling part.

2. The filling machine for producing Chinese herbal medicine toothpaste as claimed in claim 1, wherein: the stirring rod (25) is of a bent pipe structure and is provided with a plurality of stirring rods at equal intervals along the circumference; the bottom of puddler (25) is equipped with the screw thread, cleaning device's connecting rod (51) one end cup joints mutually and passes through the thread tightening with the bottom of puddler (25).

3. The filling machine for producing Chinese herbal medicine toothpaste as claimed in claim 2, wherein: the cleaning device further comprises an elastic rod (52) and a cleaning block (53); one end of the elastic rod (52) is provided with a sliding groove, a plurality of clamping points are filled in the sliding groove, and the other end of the connecting rod (51) is limited in the sliding groove and slides between the clamping points; the other end of the elastic rod (52) is fixedly connected with the cleaning block (53).

4. The filling machine for producing Chinese herbal medicine toothpaste as claimed in claim 1, wherein: a filter screen layer (27) is also arranged in the cylinder body (21); the bottom of the cylinder body (21) is of a funnel-shaped structure, and the bottom surface of the cylinder body is provided with the through hole; the circumferential wall of the bottom end of the screw rod (24) is provided with an annular groove; the annular groove corresponds to the bottom of the cylinder body (21); the filter screen layer (27) is of a ring body structure, the outer ring of the filter screen layer (27) is limited in the small-caliber end of the barrel body (21), and the inner ring of the filter screen layer (27) is limited in the annular groove.

5. The filling machine for producing Chinese herbal medicine toothpaste as claimed in claim 1, wherein: the bottom surface of the cylinder cover (22) is also provided with a lantern ring (26); the lantern ring (26) is sleeved with the lead screw (24); a threaded sleeve is arranged in the lantern ring (26).

6. The filling machine for producing Chinese herbal medicine toothpaste as claimed in claim 1, wherein: the filling part also comprises a filling cylinder (32) and a piston (33); the filling cylinder (32) is in transmission connection with one end of the piston (33); the other end of the piston (33) is communicated with the filling pipeline (31).

7. The filling machine for producing Chinese herbal medicine toothpaste as claimed in claim 1, wherein: an opening is formed in the bottom surface of the filling pipeline (31), and the filling pipeline is communicated with the through hole of the cylinder body (21) through the opening; and a detachable sealing sleeve is arranged at the communication position of the opening and the through hole.

8. The filling machine for producing Chinese herbal medicine toothpaste as claimed in claim 1, wherein: the disinfection mechanism (4) comprises a water tank (41) and a steam outlet pipeline (42); one end of the steam outlet pipeline (42) is communicated with the top side of the water tank (41), and the other end of the steam outlet pipeline extends out of the base (12) and is communicated with the cylinder cover (22).

9. The filling machine for producing herbal toothpaste as claimed in claim 8, wherein: a heating pipe (43) and a heating box (44) are arranged in the water tank (41); one end of the heating box (44) is electrically connected with an external power supply, and the heating pipe (43) is installed at the other end.

10. The filling machine for producing herbal toothpaste as claimed in claim 8, wherein: and a pressure gauge (45) is further installed on one side of the water tank (41).