CN112402070A - Pore structure part of interbody fusion cage - Google Patents
Pore structure part of interbody fusion cage Download PDFInfo
- Publication number
- CN112402070A CN112402070A CN201910784653.6A CN201910784653A CN112402070A CN 112402070 A CN112402070 A CN 112402070A CN 201910784653 A CN201910784653 A CN 201910784653A CN 112402070 A CN112402070 A CN 112402070A
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- Prior art keywords
- cylinders
- pore
- polyhedral frame
- radiation structure
- void
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- 239000011148 porous material Substances 0.000 title claims abstract description 32
- 230000004927 fusion Effects 0.000 title abstract description 13
- 230000005855 radiation Effects 0.000 claims abstract description 18
- 239000011800 void material Substances 0.000 claims abstract description 11
- 239000000463 material Substances 0.000 claims description 6
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 4
- 229910052719 titanium Inorganic materials 0.000 claims description 4
- 239000010936 titanium Substances 0.000 claims description 4
- 239000000919 ceramic Substances 0.000 claims description 3
- 239000002131 composite material Substances 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 3
- 210000004027 cell Anatomy 0.000 abstract description 7
- 210000002449 bone cell Anatomy 0.000 abstract description 4
- 230000012010 growth Effects 0.000 abstract description 3
- 239000012620 biological material Substances 0.000 abstract description 2
- 210000000988 bone and bone Anatomy 0.000 description 9
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 238000010146 3D printing Methods 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000021164 cell adhesion Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
Abstract
The invention discloses a pore structure part of an intervertebral fusion cage, and relates to the technical field of biological materials. One embodiment of the void feature includes: a void cell; the pore unit includes: the radiation structure comprises a polyhedral frame and a radiation structure arranged in the polyhedral frame; the radiation structure comprises N cylinders, one ends of the N cylinders are connected together to form a central node positioned in the polyhedral frame, and the other ends of the N cylinders are respectively connected with one end point of the polyhedron; the central node is generated by adopting a convex hull algorithm; n is a positive integer. The embodiment can ensure enough porosity, has good elasticity and toughness, has good bearing capacity and is easy for the growth of bone cells.
Description
Technical Field
The invention relates to the technical field of biological materials, in particular to a pore structure part of an intervertebral fusion cage.
Background
The interbody fusion cage has the functions of supporting, load sharing and the like, and can better recover the intervertebral space height and the physiological curvature of the spine.
The porous structure of the existing interbody fusion cage is mostly composed of regular tetrahedron structures, each regular tetrahedron structure comprises base points arranged on four vertexes and edges connecting adjacent vertexes, the edges of the tetrahedron are longer, included angles among the edges are too large, the rigidity of the tetrahedron is smaller, the bearing capacity is insufficient, the porosity is insufficient, and therefore the growth of bone cells is not easy.
Disclosure of Invention
In view of this, the embodiment of the present invention provides a pore structure portion of an intervertebral fusion cage, which has good elasticity and toughness, good bearing capacity, and is easy for bone cell growth while ensuring sufficient porosity.
An aperture structure of an intervertebral cage according to an embodiment of the present invention includes: a void cell; the pore unit includes: the radiation structure comprises a polyhedral frame and a radiation structure arranged in the polyhedral frame; the radiation structure comprises N cylinders, one ends of the N cylinders are connected together to form a central node positioned in the polyhedral frame, and the other ends of the N cylinders are respectively connected with one end point of the polyhedron; the central node is generated by adopting a convex hull algorithm; n is a positive integer.
Optionally, N is 8.
Optionally, the void feature comprises a plurality of void cells; the side surfaces of the polyhedral frame of two adjacent pore units are overlapped.
Optionally, the cylinder is made of any one of the following materials: porous titanium, ceramic, or polymer, or composite.
Optionally, the length of the cylinder is 0.1 mm-3 mm, and the radius is 0.05 mm-1 mm; the inclination angle between any two cylinders in the radiation structure is 10-75 degrees; the porosity of the pore structure portion is 5% to 90%.
One embodiment of the above invention has the following advantages or benefits: the envelope surface of cylinder link in this application pore unit is the minimum envelope surface that generates through convex hull algorithm, and for prior art, the minimum link can vacate bigger space and give the hole to satisfy the requirement of macroporosity. The utility model provides a pore unit includes polyhedral frame and radiation structure, through setting up radiation structure in polyhedral frame for fuse the utensil and have good elasticity and toughness, bearing capacity is good.
Further effects of the above-mentioned non-conventional alternatives will be described below in connection with the embodiments.
Drawings
The drawings are included to provide a better understanding of the invention and are not to be construed as unduly limiting the invention. Wherein:
FIG. 1 is a schematic view of a polyhedral frame in accordance with a first embodiment of the present invention;
FIG. 2 is a schematic view of a radiating structure according to a first embodiment of the present invention;
FIG. 3 is a schematic view of a mesoporous cell in accordance with an embodiment of the invention;
FIG. 4 is a schematic diagram of a pore structure comprising a plurality of pore units according to one embodiment of the present invention;
fig. 5 is a schematic view of an octahedral framework in the second embodiment of the present invention.
Detailed Description
Exemplary embodiments of the present invention are described below with reference to the accompanying drawings, in which various details of embodiments of the invention are included to assist understanding, and which are to be considered as merely exemplary. Accordingly, those of ordinary skill in the art will recognize that various changes and modifications of the embodiments described herein can be made without departing from the scope and spirit of the invention. Also, descriptions of well-known functions and constructions are omitted in the following description for clarity and conciseness.
An aperture structure of an intervertebral cage according to an embodiment of the present invention includes: a void cell; as shown in fig. 1 to 4, the void cell 100 includes: a polyhedral frame 10, and a radiation structure 20 disposed within the polyhedral frame 10; the radiation structure 20 comprises a plurality of N cylinders, one ends of the N cylinders are connected together to form a central node positioned in the polyhedral frame, and the other ends of the N cylinders are respectively connected with one end point of the polyhedron; the central node is generated by adopting a convex hull algorithm; n is a positive integer.
For a set D, the intersection of all convex sets containing D is called the convex hull of D. The envelope surfaces of the plurality of cylindrical connecting ends are generated by adopting a convex hull algorithm, the generated envelope surfaces are minimum, and compared with the prior art, the minimum connecting end can vacate a larger space for pores, so that the requirement of high porosity is met. The modulus of the pore structure part is reduced, stress shielding can be prevented, and the bearing capacity is good.
The number of the sides and the vertexes of the polyhedron and the number of the cylinders can be selectively determined according to actual conditions, and the number of the cylinders is the same as that of the vertexes of the framework of the polyhedron. For example, when the polyhedral frame has a hexahedral structure, having eight vertices, the number N of cylinders is 8, see fig. 1-3; when the polyhedral frame is a regular octahedral structure, having six vertices, the number of cylinders N is 6, see fig. 5.
The porous structure of the existing interbody fusion cage is mostly composed of regular tetrahedron structures, each regular tetrahedron structure comprises base points arranged on four vertexes and edges connecting adjacent vertexes, the edges of the tetrahedron are longer, included angles among the edges are too large, the rigidity of the tetrahedron is smaller, the bearing capacity is insufficient, the porosity is insufficient, and therefore the growth of bone cells is not easy. In the invention, the length and the radius of the cylinders and the inclination angle between any two cylinders can be selectively set according to actual conditions. Illustratively, the cylinder has a length of 0.1mm to 3mm and a radius of 0.05mm to 1.0 mm; the inclination angle between any two cylinders in the radiation structure is 10-75 degrees; the porosity of the pore structure portion is 5% to 90%. The invention can improve the bearing capacity of the colleagues ensuring the large porosity.
The material of the cylinder can be selectively set according to the actual situation, for example, the cylinder is made of porous titanium material, and the hydrophilicity of the titanium alloy material is favorable for bone fusion. Of course, the cylinder is made of any one of the following materials: ceramic, or polymer, or composite.
The size of the pore unit can be flexibly changed according to the requirement of a patient, so that the porosity of the intervertebral fusion device is changed. Exemplarily, 1, scanning a target bone to obtain a bone image, wherein the target bone is a bone used as a reference for a fusion device manufacturing parameter; 2. calculating to obtain a corresponding bone elastic modulus according to the bone image; 3. and determining the size of the pore unit according to the preset structural characteristics corresponding to different bone elastic moduli, and further manufacturing the fusion cage.
The pore structure portion may include only one pore unit, or may include a plurality of pore units, for example, two or more pore units. When the pore structure portion includes a plurality of pore units, the side surfaces of the polyhedral frame of adjacent two pore units coincide, as shown in fig. 4. In this way, the porosity of the pore structure can be further increased.
The pore structure part of the invention can be manufactured by adopting a 3D printing mode. 3D printing can increase material surface roughness. The product surface that 3D printed is unevenness, and the concave surface that forms of printing is favorable to the cell to adhere to, increases the cell adhesion area, easily bone fusion.
One embodiment of the above invention has the following advantages or benefits: the envelope surface of cylinder link in this application pore unit is the minimum envelope surface that generates through convex hull algorithm, and for prior art, the minimum link can vacate bigger space and give the hole to satisfy the requirement of macroporosity. The application discloses pore unit includes polyhedral frame and radiation structure, through setting up radiation structure in polyhedral frame for porous titanium has good elasticity and toughness, and bearing capacity is good.
The above-described embodiments should not be construed as limiting the scope of the invention. Those skilled in the art will appreciate that various modifications, combinations, sub-combinations, and substitutions can occur, depending on design requirements and other factors. Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (5)
1. An aperture feature of an intervertebral cage, comprising: a void cell; the pore unit includes: the radiation structure comprises a polyhedral frame and a radiation structure arranged in the polyhedral frame; the radiation structure comprises N cylinders, one ends of the N cylinders are connected together to form a central node positioned in the polyhedral frame, and the other ends of the N cylinders are respectively connected with one end point of the polyhedron; the central node is generated by adopting a convex hull algorithm; n is a positive integer.
2. The void structure of claim 1, wherein N is 8.
3. The void structure portion of claim 1, comprising a plurality of the void cells; the side surfaces of the polyhedral frame of two adjacent pore units are overlapped.
4. The porous structural portion of claim 1, wherein the cylindrical body is made of any one of the following materials: porous titanium, ceramic, or polymer, or composite.
5. The porous structural portion of claim 1, wherein the cylinder has a length of 0.1mm to 3mm and a radius of 0.05mm to 1.0 mm; the inclination angle between any two cylinders in the radiation structure is 10-75 degrees; the porosity of the pore structure portion is 5% to 90%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910784653.6A CN112402070A (en) | 2019-08-23 | 2019-08-23 | Pore structure part of interbody fusion cage |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910784653.6A CN112402070A (en) | 2019-08-23 | 2019-08-23 | Pore structure part of interbody fusion cage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112402070A true CN112402070A (en) | 2021-02-26 |
Family
ID=74779667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910784653.6A Pending CN112402070A (en) | 2019-08-23 | 2019-08-23 | Pore structure part of interbody fusion cage |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112402070A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI779675B (en) * | 2021-06-18 | 2022-10-01 | 國立臺灣大學 | Intervertebral fusion device |
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| CN103324032A (en) * | 2012-03-22 | 2013-09-25 | 上海微电子装备有限公司 | Polyhedron main substrate, manufacturing method and processing method thereof |
| CN204971711U (en) * | 2015-05-31 | 2016-01-20 | 西安赛隆金属材料有限责任公司 | High strength aperture footpath metal bone trabecula |
| CN109622958A (en) * | 2018-12-20 | 2019-04-16 | 华中科技大学 | A method of titanium alloy implant is prepared using minimal surface porous structure |
| CN110025411A (en) * | 2018-06-12 | 2019-07-19 | 深圳市立心科学有限公司 | Invasive lumbar fusion device with elastic portion |
| CN110037832A (en) * | 2019-04-16 | 2019-07-23 | 华南协同创新研究院 | A kind of Bone Defect Repari recombiner unit structural porous bracket and processing method |
| CN211067221U (en) * | 2019-08-23 | 2020-07-24 | 北京智塑健康科技有限公司 | Pore structure part of interbody fusion cage |
-
2019
- 2019-08-23 CN CN201910784653.6A patent/CN112402070A/en active Pending
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| US20090167755A1 (en) * | 2007-12-28 | 2009-07-02 | Voth Eric J | Method and system for generating surface models of geometric structures |
| CN102686250A (en) * | 2009-11-12 | 2012-09-19 | 史密夫和内修有限公司 | Controlled randomized porous structures and methods for making same |
| CN103324032A (en) * | 2012-03-22 | 2013-09-25 | 上海微电子装备有限公司 | Polyhedron main substrate, manufacturing method and processing method thereof |
| CN204971711U (en) * | 2015-05-31 | 2016-01-20 | 西安赛隆金属材料有限责任公司 | High strength aperture footpath metal bone trabecula |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI779675B (en) * | 2021-06-18 | 2022-10-01 | 國立臺灣大學 | Intervertebral fusion device |
| US11925727B2 (en) | 2021-06-18 | 2024-03-12 | National Taiwan University | Intervertebral fusion device |
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