CN112384982A - 用于指纹识别生物样本的方法 - Google Patents

用于指纹识别生物样本的方法 Download PDF

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Publication number
CN112384982A
CN112384982A CN201980037384.5A CN201980037384A CN112384982A CN 112384982 A CN112384982 A CN 112384982A CN 201980037384 A CN201980037384 A CN 201980037384A CN 112384982 A CN112384982 A CN 112384982A
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China
Prior art keywords
nucleic acid
sample
acid molecules
genetic loci
fingerprint
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Pending
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CN201980037384.5A
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English (en)
Chinese (zh)
Inventor
亚历山大·德·钟·罗伯逊
罗希思·卡纳潘·斯里瓦斯
蒂莫西·约瑟夫·威尔逊
尼尔·彼得曼
尼科尔·杰辛达·兰伯特
哈洛克·泰兹坎
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Nexant Biological Co
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Nexant Biological Co
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Publication of CN112384982A publication Critical patent/CN112384982A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Analytical Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Data Mining & Analysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Databases & Information Systems (AREA)
  • Evolutionary Computation (AREA)
  • Software Systems (AREA)
  • Library & Information Science (AREA)
  • Primary Health Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201980037384.5A 2018-06-06 2019-06-06 用于指纹识别生物样本的方法 Pending CN112384982A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862681642P 2018-06-06 2018-06-06
US62/681,642 2018-06-06
PCT/US2019/035871 WO2019236906A1 (en) 2018-06-06 2019-06-06 Methods for fingerprinting of biological samples

Publications (1)

Publication Number Publication Date
CN112384982A true CN112384982A (zh) 2021-02-19

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980037384.5A Pending CN112384982A (zh) 2018-06-06 2019-06-06 用于指纹识别生物样本的方法

Country Status (11)

Country Link
US (1) US20210151126A1 (https=)
EP (1) EP3791012A4 (https=)
JP (2) JP2021526857A (https=)
KR (1) KR20210022622A (https=)
CN (1) CN112384982A (https=)
AU (1) AU2019280867A1 (https=)
BR (1) BR112020024646A2 (https=)
CA (1) CA3101527A1 (https=)
IL (1) IL279184A (https=)
SG (1) SG11202011652QA (https=)
WO (1) WO2019236906A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230135171A1 (en) * 2019-12-24 2023-05-04 Lexent Bio, Inc. Methods and systems for molecular disease assessment via analysis of circulating tumor dna
CN112349348B (zh) * 2020-11-05 2023-10-13 北京市农林科学院 分子标记指纹数据的比对方法、非暂存态存储介质和装置
US12518859B2 (en) * 2023-07-26 2026-01-06 Helix, Inc. Systems and methods for providing test results of gene sequencing data on a recurring basis
WO2025090739A1 (en) * 2023-10-27 2025-05-01 Grail, Inc. Systems and methods for assessing similarity between samples using genotype signatures

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1370242A (zh) * 1999-06-15 2002-09-18 基因描绘系统有限公司 基因组分布分析:一种检测复杂生物样品中多种类型生物的存在的快速方法
CN103534591A (zh) * 2010-10-26 2014-01-22 利兰·斯坦福青年大学托管委员会 通过测序分析进行的非侵入性胎儿遗传筛选
CN106460062A (zh) * 2014-05-05 2017-02-22 美敦力公司 用于scd、crt、crt‑d或sca治疗识别和/或选择的方法和组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2786564A1 (en) * 2010-01-19 2011-07-28 Verinata Health, Inc. Identification of polymorphic sequences in mixtures of genomic dna by whole genome sequencing
KR102768285B1 (ko) * 2013-02-14 2025-02-13 더 리전츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코퍼레이트 간질 폐렴의 위험을 예측하는 방법

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1370242A (zh) * 1999-06-15 2002-09-18 基因描绘系统有限公司 基因组分布分析:一种检测复杂生物样品中多种类型生物的存在的快速方法
CN103534591A (zh) * 2010-10-26 2014-01-22 利兰·斯坦福青年大学托管委员会 通过测序分析进行的非侵入性胎儿遗传筛选
CN106460062A (zh) * 2014-05-05 2017-02-22 美敦力公司 用于scd、crt、crt‑d或sca治疗识别和/或选择的方法和组合物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SOHEIL YOUSEFI等: "A SNP panel for identification of DNA and RNA specimens", BMC GENOMICS, vol. 19, no. 1, 25 January 2018 (2018-01-25), pages 1 - 12, XP021252938, DOI: 10.1186/s12864-018-4482-7 *

Also Published As

Publication number Publication date
JP2024056939A (ja) 2024-04-23
US20210151126A1 (en) 2021-05-20
SG11202011652QA (en) 2020-12-30
KR20210022622A (ko) 2021-03-03
BR112020024646A2 (pt) 2021-03-02
EP3791012A4 (en) 2022-03-09
WO2019236906A1 (en) 2019-12-12
IL279184A (en) 2021-01-31
EP3791012A1 (en) 2021-03-17
AU2019280867A1 (en) 2021-01-07
JP2021526857A (ja) 2021-10-11
CA3101527A1 (en) 2019-12-12

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Application publication date: 20210219