CN112370592B - Medical ozone therapeutic instrument capable of automatically realizing ozone autohemotherapy - Google Patents
Medical ozone therapeutic instrument capable of automatically realizing ozone autohemotherapy Download PDFInfo
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- CN112370592B CN112370592B CN202011072200.XA CN202011072200A CN112370592B CN 112370592 B CN112370592 B CN 112370592B CN 202011072200 A CN202011072200 A CN 202011072200A CN 112370592 B CN112370592 B CN 112370592B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3639—Blood pressure control, pressure transducers specially adapted therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/369—Temperature treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0216—Ozone
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Abstract
The invention belongs to the field of medical instruments and ozone therapy, and provides instrument equipment for realizing automatic ozone autohemotherapy, for this reason, the technical scheme adopted by the invention is that the medical ozone therapeutic instrument capable of automatically realizing the ozone autohemotherapy comprises: the system comprises a quality control valve, a pure oxygen generating device, a throttling and reducing valve, a flow sensor, a pressure sensor, a pipeline, a three-oxygen concentration monitoring device, an electronic control unit, a trioxygen generator, a waste gas catalytic treatment device, a gas taking one-way valve, a quantitative gas taking device, an exhaust one-way valve, a gas end filter and a blood bag; also provided with a program control throttle valve, a blood transfusion device, a blood flow sensor and a blood bag constant temperature heating sheet. The invention is mainly applied to the design and manufacture occasions of medical instruments.
Description
Technical Field
The invention belongs to the field of medical instruments and three-oxygen therapy, and particularly relates to a medical three-oxygen therapeutic instrument design capable of automatically realizing three-oxygen autohemotherapy.
Background
The three oxygen autoblood therapy is carried out by taking out venous blood of patient, adding medical oxygen (O) 3 ) Mixing, and infusing back into body to treat certain diseases. The trioxane can activate the immunologic function of a human body to a certain degree and enhance the anti-infection capability of the human body.
The treatment of spontaneous oxygen therapy comprises treatment of spontaneous oxygen therapy and treatment of spontaneous oxygen therapy. Venous blood is generally extracted by a blood taking device for 100-200 ml/time, and is treated by proper amount of trioxane and then is returned to the venous blood vessel of a patient; venous blood is generally extracted from the small autoblood by an injector for 5-10 ml/time, and is treated by trioxane for intramuscular injection.
In the treatment process of the trioxane autohemotherapy, the concentration of the trioxane and the input amount of the mixed gas of the trioxane and oxygen need to be controlled in a combined manner so as to measure the dosage of the trioxane in the blood, which is an important link in the treatment. At present, a common medical trioxygen generator can realize the production of trioxygen with a preset concentration, the preset concentration can be generally adjusted within the range of 10-150 mg/L, and the typical treatment concentration for clinically treating the spontaneous blood is 50-55 mg/L.
At present, the trioxane autohemotherapy is widely applied in clinic, the time is about 10 to 30 minutes once, except that the trioxane is prepared by depending on the preset concentration of a medical trioxane generator, other operations are manually completed by nursing staff, such as quantitative blood taking and quantitative gas taking,
the operation steps are more, a great deal of nursing working time is occupied, and the possibility of misoperation exists.
Therefore, clinically, a three-oxygen autoblood treatment device capable of realizing most operations is needed, the treatment safety is ensured, the working strength of nursing staff is reduced to the maximum extent, and the skill requirement is reduced.
The patent most similar to this application is application number CN109568699A, which describes an integrated trioxide autoblood treatment apparatus, using air as source gas, making oxygen by an oxygen generator, making trioxide, and completing the operation of mixing blood with ozone by a mixer, theoretically realizing automatic trioxide autoblood treatment. The main problems of the method are as follows: the high-efficiency molecular sieve used by the molecular sieve oxygen generator taking air as source gas has high material cost, but the absorption rate of the high-efficiency molecular sieve to nitrogen in the air cannot reach 100 percent, and the nitrogen mixed into the trioxygen generator is easy to generate toxic nitrogen oxide in a common dielectric barrier discharge type trioxygen generator; the instrument only measures the flow of the mixed gas of the trioxane and the oxygen, and can not accurately realize the quantitative gas blood mixing and the control of the concentration of the trioxane, thus leading to the uncontrolled dosage of the incoming trioxane; the mixing unit adopts a fixed cleanable reuse design, the cleaning process is complex, cross infection is easily caused by applying human blood medium, and the patient acceptance is low; when the automatic operation is carried out, if serious hemolysis phenomenon occurs in the mixer, the hemolysis phenomenon is easy to ignore, and the hemolysis phenomenon is not confirmed to be infused back into the body of a patient, so that the life of the patient is threatened.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention aims to provide instrument equipment for realizing automatic trioxyhydrous self-blood treatment, and therefore, the technical scheme adopted by the invention is that the medical ozone therapeutic apparatus capable of automatically realizing ozone self-blood treatment comprises: the system comprises a quality control valve, a pure oxygen generating device, a throttling and reducing valve, a flow sensor, a pressure sensor, a pipeline, a three-oxygen concentration monitoring device, an electronic control unit, a trioxygen generator, a waste gas catalytic treatment device, a gas taking one-way valve, a quantitative gas taking device, an exhaust one-way valve, a gas end filter and a blood bag;
when in work:
the quality control valve is opened to the waste gas end, pure oxygen enters under the control of the throttling and reducing valve, the residual gas in the pipeline is blown and discharged under the detection of the flow sensor, and after the blowing and discharging are finished, the ozone concentration monitoring device finishes the zero concentration point calibration again;
starting to prepare the ozone according to the preset concentration, and driving an ozone generator to prepare the ozone by an electronic control unit under the feedback of an ozone concentration monitoring device; meanwhile, the feedback opening and closing of the electronic control unit pressing force sensor and the flow sensor continuously control the speed of inputting pure oxygen by the throttle valve; the ozone/oxygen mixed gas with unstable concentration is directly discharged into the waste gas catalytic treatment device through the quality control valve, ozone is discharged into air after being catalytically decomposed, the concentration and the pressure of the generated ozone are stabilized, the quality control valve is opened to the production end, ozone with fixed concentration and fixed pressure passes through the air taking one-way valve, the electronic control unit controls the piston of the quantitative air taking device to move, and the ozone in the pipeline is quantitatively extracted.
After the quantitative gas taking is finished and the pressure rises stably, the piston of the quantitative gas taking device moves, the three oxygen gases for quantitative treatment are all discharged into a blood bag filled with the blood of a patient through the exhaust one-way valve and the gas final filter, the quality control valve is opened to the waste gas end, and the three oxygen gases remained in the pipeline are discharged into the waste gas catalytic treatment device and then discharged into the air.
And the blood collection and feedback monitoring device is also provided with a program control throttle valve, a blood transfusion device and a blood flow sensor, and is used for collecting blood and returning blood and monitoring a quantitative blood taking process and a returning process.
The blood bag constant temperature heating piece is also arranged and used for heating the blood bag and keeping the temperature; and the cooling device is used for cooling the entering oxygen and the three-oxygen generation device.
The invention has the characteristics and beneficial effects that:
the trioxane autoblood therapeutic apparatus can realize most of operations of automatic trioxane autoblood therapy, and simultaneously isolates high-risk steps (blood character confirmation after the trioxane treatment) in the therapy, so that the working strength of nursing staff can be greatly reduced on the basis of ensuring the safety of the autoblood therapy, and the complex steps and skill training in the process of operating the autoblood therapy by using a single medical trioxane generator are avoided.
The instrument can accurately measure the concentration of the ozone in the mixed gas by designing the quality control valve and matching with an online optical ozone concentration detection device, thereby realizing constant-concentration continuous constant-pressure air supply.
The therapeutic apparatus can realize accurate constant-pressure quantitative air-taking operation under the known concentration of the ozone through the design of the quantitative air-taking device, further realize accurate control of the absolute dosage of the ozone injected into the blood of a patient, and simultaneously conveniently realize small autoblood treatment operation aiming at intramuscular injection.
This therapeutic instrument is to conventional disposable blood bag and blood transfusion ware design, and patient's autologous blood bears by disposable consumptive material, the cross infection of avoiding, greatly increased patient's acceptance.
Description of the drawings:
FIG. 1 is a schematic structural view of a medical ozone therapeutic apparatus capable of automatically realizing ozone autohemotherapy according to the present invention.
In the figure:
1. air inlet channel
2. Air inlet filter
3. Air inlet throttling/reducing valve
4. Cooling device (Water bath cooling cycle system)
5. Three oxygen generating device
6. Three oxygen concentration on-line measuring device (ultraviolet radiation absorption method)
7. Three oxygen quality control valve (electromagnetic three-way valve)
8. Waste gas collecting and catalytic decomposing device
9. Air pressure sensor
10. Gas flowmeter (thermal excitation type)
11. Gas taking one-way valve
12. Exhaust check valve
13. Quantitative gas taking and injecting device
14. Gas end filter
15. Blood flow meter
16. Program control throttle valve
17. Blood bag oscillator
18. Blood bag constant temperature heating piece
19. Disposable blood transfusion bag (with anticoagulant inside)
20. Disposable blood transfusion device
21. Display and control console
22. Electronic control unit
23. Main box
24. Program control interface of blood transfusion apparatus
Detailed Description
Before the treatment of the three-oxygen autoblood, the nursing staff is connected with a power supply and an oxygen source (a pipeline oxygen or an oxygen bottle), a disposable blood bag is placed on a blood bag oscillator of the treatment instrument, and the conventional operations of disinfection, blood stopping, venipuncture, needle fixing, blood guiding and the like are manually finished. Operating the display and control console, inputting the parameters of each treatment program, or calling a preset treatment program. After the start button of the display and control console is pressed down, the instrument starts to work, and the treatment process starts.
Firstly, the instrument starts a quantitative blood taking process, the blood bag oscillates on the oscillator and is heated by the blood bag constant-temperature heater to keep the temperature, meanwhile, the electronic control unit monitors the blood volume entering the blood bag through the blood flow sensor, and when the set blood taking volume is reached, the electronic control unit drives the program control throttle valve to lock the blood transfusion device hose, so that the quantitative blood taking is completed.
Then, pure oxygen enters from the air inlet channel, the input oxygen is efficiently filtered through the air inlet filter, the pure oxygen enters the three-oxygen preparation system through the control of the throttle pressure reducing valve, and meanwhile, the cooling device operates to cool the oxygen and the three-oxygen generation device. The preparation and blood infusion of the trioxane comprise the following specific steps:
1. the quality control valve is opened to the waste gas end, pure oxygen enters under the control of the throttling and reducing valve, and residual gas in the pipeline is blown and discharged under the detection of the flow sensor. And after the blowing and exhausting are finished, the three-oxygen concentration monitoring device finishes the zero concentration point calibration again.
2. The preparation of trioxane is started according to the preset concentration. Under the feedback of the ozone concentration monitoring device, the electronic control unit drives the ozone generator to carry out ozone preparation; meanwhile, the feedback opening and closing of the electronic control unit pressing force sensor and the flow sensor continuously control the speed of the throttle valve for inputting pure oxygen. The mixed gas of the ozone and the oxygen with unstable concentration is directly discharged into a waste gas catalytic treatment device through a quality control valve, and the ozone is discharged into the air after being catalytically decomposed. Along with the stabilization of the concentration and the pressure of generated trioxane, the quality control valve is opened to the production end, the trioxane gas with fixed concentration and fixed pressure passes through the gas taking one-way valve, and the electronic control unit controls the piston of the quantitative gas taking device to move, so that the trioxane gas in the pipeline is quantitatively extracted.
3. After the pressure rises stably, the piston of the quantitative gas taking device moves, and the trioxygen gas for quantitative treatment is completely discharged into the blood bag of the patient through the exhaust one-way valve and the gas end filter. The quality control valve is opened to the waste gas end, and the residual oxygen gas in the pipeline is discharged into the waste gas catalytic treatment device and then into the air
After the steps are completed, the instrument can give out buzzing to remind nursing staff.
After hearing the buzzer of the operation completion of the therapeutic apparatus, the nursing staff unplugs the trioxane injection tube, vertically hangs the blood bag high, observes the blood properties in the blood bag, has the abnormalities of hemolysis, serious stratification and the like, and manually opens the manual throttle valve of the blood transfusion apparatus after confirming that no errors exist, thereby completing the autologous blood transfusion. After the blood is returned, the therapeutic apparatus gives out a blood flow alarm, the nursing staff removes the needle, the hemostasis is pressed, and the autohemotherapy is finished.
As shown in the attached figure 1, the invention is a structural schematic diagram, an automatic trioxide autoblood therapeutic apparatus,
comprises a main box body, a disposable consumable part (blood bag, blood transfusion device), a quantitative blood taking part and a blood oscillation heating part.
The inner surface of the main box body is provided with a display and control console for programming operation of nursing staff, and the surface of the box body is provided with a source gas inlet channel so as to be connected with constant-pressure pure oxygen provided by a medical oxygen bottle or a central oxygen supply pipeline. An electronic control unit is arranged in the main box body and is connected with a cooling device, a trioxane generating device, an online concentration detecting device of the trioxane, and a waste gas catalyzing and decomposing device for power supply and control; the quantitative gas taking device is connected to accurately control the gas taking amount; connecting an air inlet throttling/reducing valve, a quality control valve, a pressure sensor and a gas flowmeter so as to provide gas making parameter feedback and finished product gas quality control; the external blood transfusion programmed interface is connected with the programmed throttle valve and the blood flow sensor so as to monitor the quantitative blood measuring process and the back transfusion process.
The inside three oxygen preparation and matter accuse gas circuit of arranging of main tank body: the air inlet channel is connected with an air inlet filter, and is sequentially connected with a three-oxygen generating device, a three-oxygen concentration online monitoring device, a pressure sensor and a flow sensor after passing through an air inlet throttling/reducing valve, and the quality control valve is divided into two parts: when the quality control valve is opened to the waste gas end, the gas path is connected with the waste gas collecting catalytic decomposition device and is finally discharged into the air; when the quality control valve is opened to the production end, the gas path is connected to the quantitative gas taking device through the gas taking one-way valve, is connected to the gas final filter through the gas exhaust one-way valve, and is finally connected to the blood bag.
A blood bag constant-temperature heating sheet is attached to the blood bag oscillator outside the main box body, so that the temperature of the blood bag is suitable for being fused with the three oxygen during vibration, and the comfort level of a patient during reinfusion is improved. The blood flowmeter and the program control throttle valve which can be clamped at will are clamped on a pipeline of the disposable blood transfusion device, and the blood flow can be monitored at any time and the program control throttle valve can be controlled until the blood flow is locked.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (3)
1. A medical ozone therapeutic instrument capable of automatically realizing ozone autohemotherapy is characterized by comprising: the system comprises a quality control valve, a pure oxygen generating device, a throttling and reducing valve, a flow sensor, a pressure sensor, a pipeline, a three-oxygen concentration monitoring device, an electronic control unit, a trioxygen generator, a waste gas catalytic treatment device, a gas taking one-way valve, a quantitative gas taking device, an exhaust one-way valve, a gas end filter and a blood bag;
when in work:
the quality control valve is opened to the waste gas end, pure oxygen enters under the control of the throttling pressure reducing valve, the residual gas in the pipeline is blown and discharged under the detection of the flow sensor, and after the blowing and the discharging are finished, the three-oxygen concentration monitoring device finishes the zero concentration point calibration again;
starting to prepare the ozone according to the preset concentration, and driving an ozone generator to prepare the ozone by an electronic control unit under the feedback of an ozone concentration monitoring device; meanwhile, the feedback opening and closing of the electronic control unit pressing force sensor and the flow sensor continuously control the speed of inputting pure oxygen by the throttle valve; the ozone/oxygen mixed gas with unstable concentration is directly discharged into a waste gas catalytic treatment device through a quality control valve, ozone is discharged into air after being subjected to catalytic decomposition, the concentration and the pressure of the generated ozone are stabilized, the quality control valve is opened to a production end, ozone with fixed concentration and fixed pressure passes through a gas taking one-way valve, an electronic control unit controls a piston of a quantitative gas taking device to move, and the ozone in a pipeline is quantitatively extracted;
after the quantitative gas taking is finished and the pressure rises stably, the piston of the quantitative gas taking device moves, the three oxygen gases for quantitative treatment are all discharged into a blood bag filled with the blood of a patient through the exhaust one-way valve and the gas final filter, the quality control valve is opened to the waste gas end, and the three oxygen gases remained in the pipeline are discharged into the waste gas catalytic treatment device and then discharged into the air.
2. The medical ozone therapeutic apparatus capable of automatically realizing ozone autohemotherapy as claimed in claim 1, wherein a program-controlled throttle valve, a blood transfusion device and a blood flow sensor are further provided for blood sampling and blood transfusion, and monitoring a quantitative blood sampling process and a blood transfusion process.
3. The medical ozone therapeutic apparatus capable of automatically realizing ozone autohemotherapy as claimed in claim 1, wherein a blood bag constant temperature heating sheet is further provided for heating the blood bag and maintaining the temperature; and the cooling device is used for cooling the entering oxygen and the three-oxygen generation device.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011072200.XA CN112370592B (en) | 2020-10-09 | 2020-10-09 | Medical ozone therapeutic instrument capable of automatically realizing ozone autohemotherapy |
| PCT/CN2021/112516 WO2022073383A1 (en) | 2020-10-09 | 2021-08-13 | Medical ozone therapy instrument capable of automatically achieving ozonated autohemotherapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011072200.XA CN112370592B (en) | 2020-10-09 | 2020-10-09 | Medical ozone therapeutic instrument capable of automatically realizing ozone autohemotherapy |
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| CN112370592A CN112370592A (en) | 2021-02-19 |
| CN112370592B true CN112370592B (en) | 2022-08-30 |
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| WO (1) | WO2022073383A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112370592B (en) * | 2020-10-09 | 2022-08-30 | 天津大学 | Medical ozone therapeutic instrument capable of automatically realizing ozone autohemotherapy |
| CN113244476A (en) * | 2021-05-11 | 2021-08-13 | 无锡市第二人民医院 | Three oxygen autohemorrhaging therapeutic instrument |
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| CN1939545A (en) * | 2005-09-30 | 2007-04-04 | 郭罕斌 | High-pressure ozone blood purifier and purification |
| CN101347643A (en) * | 2008-08-12 | 2009-01-21 | 宁波天益医疗器械有限公司 | Ozone immunoregulation equipment |
| EP2213317A1 (en) * | 2009-02-03 | 2010-08-04 | Bellco S.r.l. | Ozone-therapy blood treatment |
| CN201603164U (en) * | 2010-02-11 | 2010-10-13 | 淄博前沿医疗器械有限公司 | Ozone autohemotherapeutic apparatus |
| CN102019003A (en) * | 2009-09-16 | 2011-04-20 | 朱戈 | A fully automated smart autologous transfusion equipment with the help of ozone |
| CN109568699A (en) * | 2019-01-09 | 2019-04-05 | 无锡市第三人民医院 | Medicinal ozone therapeutic instrument |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN202802300U (en) * | 2012-07-09 | 2013-03-20 | 彭勇 | Ozone autologous blood transfusion instrument |
| CN203577022U (en) * | 2013-12-09 | 2014-05-07 | 金竹沁 | Ozone therapeutic instrument |
| SE541036C2 (en) * | 2014-09-15 | 2019-03-12 | Sangair Ab | Apparatus and system for ozonating blood, and method for ozonating blood prior to storage |
| CN211576692U (en) * | 2019-11-25 | 2020-09-25 | 烟台裕祥精细化工有限公司 | Sampling device with nitrogen-filled protective layer |
| CN112370592B (en) * | 2020-10-09 | 2022-08-30 | 天津大学 | Medical ozone therapeutic instrument capable of automatically realizing ozone autohemotherapy |
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2020
- 2020-10-09 CN CN202011072200.XA patent/CN112370592B/en active Active
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2021
- 2021-08-13 WO PCT/CN2021/112516 patent/WO2022073383A1/en active Application Filing
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1939545A (en) * | 2005-09-30 | 2007-04-04 | 郭罕斌 | High-pressure ozone blood purifier and purification |
| CN101347643A (en) * | 2008-08-12 | 2009-01-21 | 宁波天益医疗器械有限公司 | Ozone immunoregulation equipment |
| EP2213317A1 (en) * | 2009-02-03 | 2010-08-04 | Bellco S.r.l. | Ozone-therapy blood treatment |
| CN102019003A (en) * | 2009-09-16 | 2011-04-20 | 朱戈 | A fully automated smart autologous transfusion equipment with the help of ozone |
| CN201603164U (en) * | 2010-02-11 | 2010-10-13 | 淄博前沿医疗器械有限公司 | Ozone autohemotherapeutic apparatus |
| CN109568699A (en) * | 2019-01-09 | 2019-04-05 | 无锡市第三人民医院 | Medicinal ozone therapeutic instrument |
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| CN112370592A (en) | 2021-02-19 |
| WO2022073383A1 (en) | 2022-04-14 |
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