CN112353462A - Clinical stem cell extraction puncture structure - Google Patents
Clinical stem cell extraction puncture structure Download PDFInfo
- Publication number
- CN112353462A CN112353462A CN202011184975.6A CN202011184975A CN112353462A CN 112353462 A CN112353462 A CN 112353462A CN 202011184975 A CN202011184975 A CN 202011184975A CN 112353462 A CN112353462 A CN 112353462A
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- China
- Prior art keywords
- motor
- extraction
- layer board
- guide pipe
- connecting block
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3476—Powered trocars, e.g. electrosurgical cutting, lasers, powered knives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/025—Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/025—Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
- A61B2010/0258—Marrow samples
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Prostheses (AREA)
- Extraction Or Liquid Replacement (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a clinical stem cell extraction puncture structure, and discloses a structure which respectively drives a rotating blade and a spiral shaft to rotate through a double-shaft motor, penetrates into a medullary cavity and performs negative pressure stem cell extraction. The utility model discloses a bearing plate, including bearing plate, apron, motor case, connecting block, connecting ring, connecting block, connecting hole, connecting ring, connecting block, miniature motor, fixed ring, solid fixed ring, guide pipe, arc spacing groove, two connecting block outward flanges, two connecting holes, four extraction pipes's one end correspondence and connecting hole intercommunication, the other end correspondence and guide pipe are linked together, and the miniature motor is arranged in on the layer board, and the layer board below is arranged in to the motor case, motor case and fixed ring are coaxial, and the guide pipe is arranged perpendicularly to the guide pipe, and one side edge of layer board is opened there is.
Description
The application has the following application numbers: 2018104303393, the name is: the invention patent application of the 'clinical medicine stem cell extraction puncture structure' is divided into separate applications, and the application dates of the original applications are as follows: year 2018, month 05, and day 08.
Technical Field
The invention discloses a clinical stem cell extraction puncturing structure, relates to a structure for performing stem cell extraction puncturing on stem cell transplantation in clinical medical treatment, and belongs to the field of medical instruments. In particular to a structure which respectively drives a rotating blade and a spiral shaft to rotate through a double-shaft motor, penetrates into a medullary cavity and absorbs stem cells under negative pressure.
Background
At present, stem cells in medicine are cells capable of self-replicating, can be differentiated into multiple functional cells under specific physiological conditions, have different functions according to the development stage of the stem cells, when partial stem cells of a patient are insufficient or run away, stem cell transplantation needs to be carried out, the stem cells mostly exist in a medullary cavity of bone, are extracted through red marrow and yellow marrow, when being extracted, permeable bone needs to be penetrated and extend into the medullary cavity for extraction, most of the existing stem cell collecting devices adopt a needle tube for manual extraction, the extraction efficiency is low, the penetration of the needle tube is poor, when being extracted, the needle tube can move out of position and affect the extraction of the stem cells, the error probability is greatly increased, and because the mechanism in the medullary cavity is complex, when the needle tube is blocked during extraction, the extraction efficiency or the extraction action is affected, the pressure is collected manually and is different, the extraction efficiency and speed of stem cells are different, and the stability in the marrow cavity is poor.
Disclosure of Invention
In order to improve the situation, the clinical stem cell extraction puncture structure provided by the invention is a structure which respectively drives a rotating blade and a spiral shaft to rotate through a double-shaft motor, penetrates into a medullary cavity and performs negative pressure stem cell extraction.
The clinical stem cell extraction puncture structure is realized as follows: the invention relates to a puncture structure for extracting clinical stem cells, which consists of a main body fixing device and a broken wall extracting device, wherein the main body fixing device consists of a cover plate, connecting blocks, connecting holes, a supporting plate, a fixing ring, extracting pipes, a guide pipe, a motor box and sealing strips, the fixing ring is arranged on the supporting plate and positioned above the supporting plate, the cover plate is arranged on the fixing ring, the motor box is arranged on the supporting plate and positioned below the supporting plate, the motor box and the fixing ring are coaxial, the guide pipe is vertically arranged on the motor box and communicated with the motor box, one side edge of the supporting plate is provided with an arc-shaped limiting groove, the two connecting blocks are symmetrically arranged on the supporting plate and positioned at two sides of the fixing ring, the sealing strips are correspondingly arranged at the outer edge of the connecting blocks, the connecting blocks are provided with two connecting holes, one ends of the four extracting, The miniature motor is arranged in the motor box and is a double-shaft motor, two ends of a motor shaft of the miniature motor are respectively arranged in the fixing ring and the guide pipe, the rotating blade is arranged on the motor shaft and positioned in the fixing ring, the compression spring is arranged between the miniature motor and the bottom of the motor box, the end face of the other end of the motor shaft of the miniature motor is provided with the clamping groove, the transmission rod is arranged in the guide pipe, the cross section of the transmission rod is rectangular, one end of the hollow pipe is arranged in the guide pipe and is communicated with the guide pipe, one end of the hollow pipe is connected with the transmission rod, one end of the spiral rod is arranged at the other end of the hollow pipe, the spiral rod is of a hollow structure, and the other end of the spiral rod is provided.
When the bone marrow stem extraction device is used, the extraction bag is sleeved on the connecting block and is attached and sealed with the sealing strip, gas in the extraction bag is emptied, then the micro motor is started, the motor shaft rotates to drive the rotating blades in the fixing ring to rotate, the fixing ring is pushed to move towards one side of the supporting plate, the micro motor is further pushed to extrude the compression spring, the other end of the motor shaft moves in the guide pipe and is attached with the transmission rod, when the clamping groove in the motor shaft is attached with the transmission rod, the transmission rod is clamped and transmitted with the motor shaft through the clamping groove, the hollow rod drives the screw rod to rotate, the screw rod rotates along the bone to enter, the screw rod rotates gradually to enter the bone and contact with the bone marrow, when the screw rod penetrates through the bone, the fixing ring stops being pressed down, the compression spring resets to push back the micro motor, the motor shaft is separated from the transmission rod, the screw rod stops rotating, the motor shaft, enters from the extracting hole on the screw rod, enters into the guide tube along the spiral tube, and enters into the extracting bag along the communicating tube, because the extracting bag is negative pressure, when the stem cell extracting sample is communicated with the extracting bag, the micro motor is stopped, the stem cells are extracted into the extracting bag through the pressure difference between the inside of the bone and the inside of the extracting bag,
the motor box and the fixing ring are coaxial, so that the coaxiality of the micro motor in working can be ensured, the working vibration of the micro motor is minimized, and the vibration retreat of the spiral rod in the extraction process is reduced;
the connecting block is provided with two connecting holes, so that the number of extraction channels can be increased, and the extraction efficiency is improved;
one ends of the four extraction pipes are correspondingly communicated with the connecting holes, the other ends of the four extraction pipes are correspondingly communicated with the guide pipes, a multi-strand extraction pipeline can be formed, the extraction amount is ensured, the problem of unsmooth extraction caused by single-channel blockage is avoided, and the extraction efficiency is improved;
the micro motor is a double-shaft motor, can simultaneously drive the rotary impeller to rotate and exhaust air, and drives the transmission rod to rotate to screw in for puncture at the other end, so that the capability of puncturing and wall breaking is improved;
the compression spring can be attached to the transmission rod to drive the spiral rod to carry out rotary puncture after the micro motor is compressed, and the compression spring is reset to enable the micro motor to reset and stop puncture after the micro motor is punctured to a position, so that tissue in the medullary cavity is prevented from being wound and damaged;
the end face of the other end of the motor shaft of the micro motor is provided with a clamping groove, the clamping groove can be clamped with a transmission rod to carry out rotary driving, and transmission is carried out through opening and closing of the clamping groove;
the section of the transmission rod is rectangular, the guide pipe can be divided into two areas which correspond to the extraction pipes respectively, the extracted stem cells are shunted, and the collection balance is improved;
the purpose of stem cell extraction and puncture is achieved.
Has the beneficial effects.
The structure is simple, and the device is convenient and practical.
And secondly, the extraction efficiency of the stem cells can be improved.
Thirdly, damage to the medullary cavity caused by puncture can be avoided.
And fourthly, the stem cells can be extracted through negative pressure, and the multi-channel extraction is carried out simultaneously, so that the blockage is avoided.
Drawings
FIG. 1 is a perspective exploded view of the puncture structure for clinical stem cell extraction according to the present invention.
Fig. 2 is a three-dimensional structure view of the micro-motor of the clinical stem cell extraction puncture structure of the present invention, and only shows the connection structure on the micro-motor.
In the attached drawings
Wherein the parts are: rotating vane (1), apron (2), drive shaft (3), connecting block (4), connecting hole (5), layer board (6), solid fixed ring (7), extraction pipe (8), stand pipe (9), hollow tube (10), hob (11), motor case (12), sealing strip (13), micro motor (14), draw-in groove (15), compression spring (16), transfer line (17).
The specific implementation mode is as follows:
the invention relates to a clinical stem cell extraction puncture structure, which is realized in such a way that when in use, an extraction bag is sleeved on a connecting block (4) and is jointed and sealed with a sealing strip (13), gas in the extraction bag is exhausted, then a micro motor (14) is started, a motor shaft rotates to drive a rotating blade (1) in a fixing ring (7) to rotate, the fixing ring (7) is pushed to enable the fixing ring (7) to move towards one side of a supporting plate (6), and further the micro motor (14) is pushed to extrude a compression spring (16), so that the other end of the motor shaft moves in a guide pipe (9) and is jointed with a transmission rod (17), when a clamping groove (15) on the motor shaft is jointed with the transmission rod (17), the transmission rod (17) is clamped and transmitted with the motor shaft through the clamping groove (15), the hollow rod drives a spiral rod (11) to rotate, and the spiral rod (11) rotates to enter, the stem cell extraction sample is rotated step by step to enter a bone to be contacted with bone marrow, when a screw rod (11) penetrates through the bone, the pressing down of a fixing ring (7) is stopped, a compression spring (16) is reset to push a micro motor (14) back, a motor shaft is separated from a transmission rod (17), the screw rod (11) stops rotating, the motor shaft continues to work to drive a rotating blade (1) to rotate to extract stem cells in the bone, the stem cells enter from an extraction hole on the screw rod (11), enter a guide pipe (9) along a spiral pipe and enter an extraction bag along a communication pipe, because the extraction bag is in negative pressure, when the stem cell extraction sample is communicated with the extraction bag, the micro motor (14) is stopped, and the stem cells are extracted into the extraction bag through the pressure difference between the bone and the extraction bag,
the motor box (12) and the fixing ring (7) are coaxial, so that the coaxiality of the micro motor (14) in working can be ensured, the working vibration of the micro motor (14) is minimized, and the vibration retreat of the screw rod (11) in the extraction process is reduced;
two connecting holes (5) are formed in the connecting block (4), so that the number of extraction channels can be increased, and the extraction efficiency is improved;
one end of each of the four extraction pipes (8) is correspondingly communicated with the connecting hole (5), and the other end of each of the four extraction pipes is correspondingly communicated with the guide pipe (9), so that a plurality of extraction pipes (8) can be formed, the extraction amount is ensured, unsmooth extraction caused by single-channel blockage is avoided, and the extraction efficiency is improved;
the micro motor (14) is a double-shaft motor, can simultaneously drive the rotary impeller to rotate for air suction, and drives the transmission rod (17) to rotate for screw-in puncture at the other end, so that the capability of puncturing and wall breaking is improved;
the compression spring (16) can be attached to the transmission rod (17) to drive the spiral rod (11) to carry out rotary puncture after the micro motor (14) is compressed, and the compression spring (16) is reset to enable the micro motor (14) to reset and stop puncture after the puncture is in place, so that tissue in a medullary cavity is prevented from being wound and damaged;
a clamping groove (15) is formed in the end face of the other end of the motor shaft of the micro motor (14), the clamping groove and the transmission rod (17) can be clamped to carry out rotary driving, and transmission is carried out through opening and closing of the clamping groove (15);
the section of the transmission rod (17) is rectangular, the interior of the guide pipe (9) can be divided into two areas which correspond to the extraction pipes (8) respectively, extracted stem cells are shunted, and the collection balance is improved;
the purpose of stem cell extraction and puncture is achieved.
Claims (2)
1. Clinical stem cell extraction puncture structure, characterized by: comprises main part fixing device and broken wall draw-out device, and main part fixing device comprises apron, connecting block, connecting hole, layer board, solid fixed ring, extraction pipe, stand pipe, motor case and sealing strip, and solid fixed ring arranges in on the layer board, and is located the layer board top, and solid fixed ring is arranged in to the apron, and on the layer board was arranged in to the motor case, and was located the layer board below, motor case and solid fixed ring are coaxial, and on the motor case was arranged perpendicularly to the stand pipe, and was linked together with the motor case, and open at one side edge of layer board has the arc spacing groove, and two connecting block symmetries were arranged in on the layer board, and were located solid fixed ring both sides, it has two connecting holes to open on the connecting block, and the connecting block outward flange was arranged in to a plurality of sealing strip correspondences, and the connecting hole intercommunication of the one, The miniature motor is arranged in the motor box and is a double-shaft motor, two ends of a motor shaft of the miniature motor are respectively arranged in the fixing ring and the guide pipe, the rotating blade is arranged on the motor shaft and is positioned in the fixing ring, the compression spring is arranged between the miniature motor and the bottom of the motor box, the end face of the other end of the motor shaft of the miniature motor is provided with the clamping groove, the transmission rod is arranged in the guide pipe, one end of the hollow pipe is arranged in the guide pipe and is communicated with the guide pipe, one end of the hollow pipe is connected with the transmission rod, one end of the spiral rod is arranged at the other end of the hollow pipe, the spiral rod is of a hollow structure, and the other end of the;
the micro motor can simultaneously drive the rotary impeller to rotationally exhaust air, and the other end drives the transmission rod to rotate to screw in for puncture.
2. The clinical stem cell extraction puncture structure according to claim 1, wherein the transmission rod has a rectangular cross section, and can divide the guide tube into two regions, and the two regions respectively correspond to the extraction tubes for shunting the extracted stem cells.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011184975.6A CN112353462A (en) | 2018-05-08 | 2018-05-08 | Clinical stem cell extraction puncture structure |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011184975.6A CN112353462A (en) | 2018-05-08 | 2018-05-08 | Clinical stem cell extraction puncture structure |
| CN201810430339.3A CN108836444B (en) | 2018-05-08 | 2018-05-08 | Clinical medicine stem cell extraction puncture structure |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810430339.3A Division CN108836444B (en) | 2018-05-08 | 2018-05-08 | Clinical medicine stem cell extraction puncture structure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112353462A true CN112353462A (en) | 2021-02-12 |
Family
ID=64212752
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011199798.9A Withdrawn CN112353463A (en) | 2018-05-08 | 2018-05-08 | Stem cell extraction puncture structure |
| CN202011184975.6A Withdrawn CN112353462A (en) | 2018-05-08 | 2018-05-08 | Clinical stem cell extraction puncture structure |
| CN201810430339.3A Active CN108836444B (en) | 2018-05-08 | 2018-05-08 | Clinical medicine stem cell extraction puncture structure |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011199798.9A Withdrawn CN112353463A (en) | 2018-05-08 | 2018-05-08 | Stem cell extraction puncture structure |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810430339.3A Active CN108836444B (en) | 2018-05-08 | 2018-05-08 | Clinical medicine stem cell extraction puncture structure |
Country Status (1)
| Country | Link |
|---|---|
| CN (3) | CN112353463A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113440181A (en) * | 2021-07-06 | 2021-09-28 | 中南大学湘雅医院 | Biological tissue biopsy sampling device based on endoscopic system |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4142517A (en) * | 1976-07-23 | 1979-03-06 | Contreras Guerrero De Stavropo | Apparatus for extracting bone marrow specimens |
| US5913859A (en) * | 1997-07-01 | 1999-06-22 | Shapira; Ira L. | Apparatus for extracting bone marrow |
| US7458940B2 (en) * | 2000-11-06 | 2008-12-02 | Suros Surgical Systems, Inc. | Biopsy apparatus |
| GB2376633B (en) * | 2000-11-06 | 2004-11-10 | Suros Surgical Systems Inc | Biopsy apparatus |
| US20030225344A1 (en) * | 2002-05-31 | 2003-12-04 | Vidacare Corporation | Apparatus and method to access the bone marrow for oncology and stem cell applications |
| CN101543414B (en) * | 2004-07-09 | 2011-03-23 | 巴德血管外围设备公司 | Transport system for biopsy device |
| JP2007020630A (en) * | 2005-07-12 | 2007-02-01 | Mizuho Co Ltd | Puncture needle for sampling bone marrow and cancellous bone agitation needle used for the same |
| US7854706B2 (en) * | 2007-12-27 | 2010-12-21 | Devicor Medical Products, Inc. | Clutch and valving system for tetherless biopsy device |
| KR100909476B1 (en) * | 2008-11-18 | 2009-07-28 | 원광대학교산학협력단 | Bone-marrow extractor |
| CN204863306U (en) * | 2015-08-24 | 2015-12-16 | 广州爱锘德医疗器械有限公司 | Organize extraction element |
| CN107773274A (en) * | 2016-08-31 | 2018-03-09 | 陈世辉 | Spiral soft tissue biopsy needle |
-
2018
- 2018-05-08 CN CN202011199798.9A patent/CN112353463A/en not_active Withdrawn
- 2018-05-08 CN CN202011184975.6A patent/CN112353462A/en not_active Withdrawn
- 2018-05-08 CN CN201810430339.3A patent/CN108836444B/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113440181A (en) * | 2021-07-06 | 2021-09-28 | 中南大学湘雅医院 | Biological tissue biopsy sampling device based on endoscopic system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108836444B (en) | 2020-12-01 |
| CN108836444A (en) | 2018-11-20 |
| CN112353463A (en) | 2021-02-12 |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20210518 Address after: Room B505, 12 Kaihua Road, Huayuan Industrial Zone, Binhai New Area, Tianjin 300451 Applicant after: Cui Shoubin Address before: 221000 Science and Technology Building, Xuzhou Science and Technology Avenue, Jiangsu Province Applicant before: XUZHOU LANHU INFORMATION TECHNOLOGY Co.,Ltd. |
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| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20210212 |