CN112312866A - Nasal ventilation improving device - Google Patents

Nasal ventilation improving device Download PDF

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Publication number
CN112312866A
CN112312866A CN201980041075.5A CN201980041075A CN112312866A CN 112312866 A CN112312866 A CN 112312866A CN 201980041075 A CN201980041075 A CN 201980041075A CN 112312866 A CN112312866 A CN 112312866A
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CN
China
Prior art keywords
nasal
nasal ventilation
improving device
nose
generating composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980041075.5A
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Chinese (zh)
Inventor
山中雅史
十田哲郎
中马章孝
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Kobayashi Pharmaceutical Co Ltd
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Kobayashi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kobayashi Pharmaceutical Co Ltd filed Critical Kobayashi Pharmaceutical Co Ltd
Publication of CN112312866A publication Critical patent/CN112312866A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/01Orthopaedic devices, e.g. splints, casts or braces
    • A61F5/08Devices for correcting deformities of the nose ; Devices for enlarging the nostril, e.g. for breathing improvement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F7/03Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/08Warming pads, pans or mats; Hot-water bottles

Abstract

A nasal ventilation improving device (1) is worn on the nose for improving nasal ventilation. The nasal ventilation improving device (1) is provided with a pair of accommodating parts (2) for accommodating a chemical heat-generating composition (4) and a connecting part (3) for connecting the pair of accommodating parts (2). The chemical exothermic composition (4) is a tablet molded body produced by tablet molding a raw material. In addition, an elastic member (5) for stretching the side wall of the nose outward when the nose is worn is disposed on the connection part (3).

Description

Nasal ventilation improving device
Technical Field
The present invention relates to a nasal ventilation improving device to be worn on the nose to improve nasal ventilation.
Background
For example, rhinitis symptoms such as nasal obstruction may be caused by cold, pollinosis, and the like.
As a means for improving rhinitis symptoms such as nasal obstruction, for example, a nose patch (nose pack) disclosed in patent document 1 is cited. The nasal patch of patent document 1 is worn on the face and intended to improve rhinitis symptoms by heating the nasal cavity or the paranasal cavity with its heat generating element.
Patent document
Patent document 1: JP-A11-347059
Disclosure of Invention
(problems to be solved by the invention)
However, the nose patch of patent document 1 has a large wearing area, and therefore, some people may feel uncomfortable when wearing the nose patch.
The present invention has been made in view of the above circumstances, and an object of the present invention is to reduce the wearing area of a nasal ventilation improving device that is worn on the nose to improve nasal ventilation.
(means for solving the problems)
The nasal ventilation improving device according to the present invention is a nasal ventilation improving device to be worn on the nose to improve nasal ventilation, and includes a pair of housing portions for housing a chemical heat-generating composition, which is a tablet molded body, and a connecting portion for connecting the pair of housing portions. Here, the molded tablet is produced by tablet-molding a raw material. Note that the tableting refers to a shape of a tablet obtained by pressing a raw material with a tableting machine (the same applies hereinafter).
According to this configuration, since the chemical heat-generating composition is a tablet molded body, the volume of the chemical heat-generating composition can be reduced. Therefore, the housing portion can be miniaturized while maintaining the heat generation temperature. This can reduce the wearing area of the nasal ventilation improving device.
In the above configuration, an elastic member may be disposed in the connection portion, and the elastic member may stretch a side wall of the nose outward when the nasal ventilation improving device is worn.
With this configuration, the nasal cavity can be dilated by the elastic member, and thus the nasal obstruction removing effect can be improved.
In the above configuration, the distance between the centers of the pair of receiving portions may be 55mm to 90 mm.
With this configuration, the housing portion can be disposed at an acupoint called "nose-through acupoint" which is effective for nasal obstruction upon stimulation. Therefore, the nasal plug can warm the nasal through points and improve the effect of eliminating the nasal obstruction. In addition, in the case where the elastic member is disposed on the connection portion, if the housing portion is positioned on the "nose bridge", the elastic member can be disposed at a position appropriate for stretching the side wall of the nose outward.
(effect of the invention)
According to the present invention, the wearing area of the nasal ventilation improving device worn on the nose for improving nasal ventilation can be reduced.
Drawings
Fig. 1 is a schematic view showing a nasal ventilation improving device according to an embodiment of the present invention, wherein (a) is a schematic plan view, and (B) is a schematic cross-sectional view of (a) taken along the X-X line.
Fig. 2 is a schematic view showing a state in which the nasal ventilation improving device is worn.
Fig. 3 is a schematic cross-sectional view corresponding to fig. 1 (B) showing a modification of the nasal ventilation improving device.
FIG. 4 is a schematic view showing a sample according to an example of the present invention, wherein (A) is a schematic plan view, and (B) is a schematic cross-sectional view of the line Y-Y of (A).
Fig. 5 is data showing heat generation characteristics.
Fig. 6 is a graph showing heat generation temperature versus time.
Fig. 7 is a graph showing the degree of improvement in nasal obstruction in the case of breathing with both nostrils.
Fig. 8 is a graph showing the degree of improvement in nasal congestion when breathing is performed only in one nostril in which the degree of nasal congestion is strong.
Fig. 9 is a graph showing the degree of improvement in nasal congestion when breathing is performed only in one nostril in which the degree of nasal congestion is weak.
Detailed Description
Hereinafter, embodiments of the present invention will be described with reference to the drawings.
Fig. 1 is a schematic view showing a nasal ventilation improving device according to an embodiment of the present invention, wherein (a) is a schematic plan view, and (B) is a schematic cross-sectional view of (a) taken along the X-X line. The nasal ventilation improving device 1 according to the present embodiment is worn on the nose to improve nasal ventilation, and includes a pair of housing portions 2 and a connecting portion 3 connecting the pair of housing portions 2. The pair of housing parts 2 each house a chemical heat generating composition 4. Further, an elastic member 5 that stretches the side wall of the nose outward when worn is disposed in the connection portion 3.
The nasal ventilation improving device 1 includes a front-side sheet member 6, a back-side sheet member 7, an adhesive layer 8, and a peeling member 9.
The front sheet member 6 has protruding portions 6a protruding toward the front side on both ends in the longitudinal direction, and the accommodating portion 2 is configured by the protruding portions 6a and the rear sheet member 7. The elastic member 5 is disposed between the front sheet member 6 and the back sheet member 7. The front sheet member 6 and the back sheet member 7 are bonded to each other with an adhesive agent not shown, for example.
The protruding portion 6a has a circular shape in plan view, and the internal space of the housing portion 2 is substantially cylindrical with a low height. The overall shape of the front-side sheet member 6, the back-side sheet member 7, the adhesive layer 8, and the peeling member 9 in plan view gradually increases in width from the center position in the longitudinal direction to the center position of the housing portion 2 in the longitudinal direction, and has a circular shape on the end side of the center position of the housing portion 2 in the longitudinal direction.
The adhesive layer 8 is formed on the back surface of the back-surface-side sheet member 7. The peeling member 9 is attached to the back surface of the adhesive layer 8 in a state of being peelable from the adhesive layer 8. In the present embodiment, the adhesive layer 8 is formed on the entire back surface of the back-surface-side sheet member 7, but may be formed only in a partial region.
The chemical heat-generating composition 4 is a heat-generating composition used in a so-called disposable warm patch (chemical warm patch). The chemical heat-generating composition 4 generally contains metal powder such as iron powder, metal halide such as salt, water, activated carbon powder, a water-retaining material, and the like, by utilizing the heat of oxidation of metal. The chemical heat-generating composition 4 may further contain a temperature control agent for controlling the maximum heat-generating temperature (see, for example, patent No. 6273481).
The chemical exothermic composition 4 is a tablet molded body produced by tablet molding a raw material. The tablet shape is a low-height substantially cylindrical shape (circular shape in plan view) conforming to the shape of the internal space of the housing portion 2. However, the shape of the molded tablet is not limited to this, and may be, for example, a prism shape.
The area of the chemical heat-generating composition 4 in plan view is, for example, 200mm2~500mm2More preferably 250mm2~450mm2Most preferably 300mm2~400mm2. The area of the chemical heat-generating composition 4 in a plan view is less than 200mm2In the case of (3), a sufficient nasal obstruction removing effect may not be obtained. The area of the chemical heat-generating composition 4 in a plan view exceeds 500mm2In the case of (3), a large amount of the chemical heat-generating composition 4 is required, which may increase the production cost.
The front sheet member 6 and the back sheet member 7 are air-permeable materials, and are made of, for example, nonwoven fabric using polyethylene, polypropylene, or the like. In the present embodiment, the front sheet member 6 and the back sheet member 7 are made of the same material, but may be made of different materials.
The moisture permeability of the front sheet member 6 and the back sheet member 7 is, for example, 600 g/(m)2·24h)~20000g/(m224h), more preferablyIs selected to be 1000 g/(m)2·24h)~10000g/(m224h), most preferably 2000 g/(m)2·24h)~8000g/(m224 h). Here, the definition of the moisture permeability (water vapor permeability) is in accordance with JIS K7129 (the same applies hereinafter).
The moisture permeability is less than 600 g/(m)224h), the chemical exothermic composition 4 may not be heated up rapidly, and nasal obstruction may not be removed rapidly. When the moisture permeability exceeds 20000 g/(m)224h), the heat generation reaction of the chemical heat-generating composition 4 is excessively excited, and the heat generation time may be shortened.
As characteristics relating to the heat generation temperature (temperature on the skin side), there are a rise time (in the present embodiment, a time from 31.5 ℃ to 39.9 ℃), a maximum temperature, and a duration time (in the present embodiment, a time of 40 ℃ or more). Here, the method of measuring the heat generation temperature is in accordance with the "usual method" of JIS S4100 (hereinafter, the same applies).
The rise time is, for example, preferably within 60 seconds, more preferably within 50 seconds, and most preferably within 40 seconds. If the rise time exceeds 60 seconds, it may be difficult to quickly remove the nasal obstruction after wearing the nasal ventilation improving device 1.
The maximum temperature is, for example, preferably 43 to 65 ℃, more preferably 43 to 60 ℃, and most preferably 43 to 55 ℃. When the maximum temperature is less than 43 ℃, the temperature does not become 43 ℃ which is necessary for good blood circulation. When the maximum temperature exceeds 65 ℃, not only the possibility of low-temperature burn but also the heat generation time may be shortened.
The duration is, for example, preferably 10 minutes to 3 hours, more preferably 10 minutes to 2 hours, and most preferably 10 minutes to 1 hour. If the duration is less than 10 minutes, a sufficient nasal obstruction removal effect may not be obtained. If the duration exceeds 3 hours, not only may low-temperature burn occur, but also a large amount of the chemical heat-generating composition 4 may be required, which may increase the production cost.
In the present embodiment, the chemical heat-generating composition 4 is in contact with the air via the protruding portion 6a of the front-side sheet member 6 of the housing portion 2, and therefore the protruding portion 6a serves as a ventilation portion for bringing the chemical heat-generating composition 4 into contact with the air.
The shape and material of the elastic member 5 are not particularly limited as long as the side wall of the nose can be stretched outward when worn. In the illustrated example of fig. 1, the elastic member 5 has a long plate shape and a rectangular shape in a plan view. As a material of the elastic member 5, for example, synthetic resin such as polyester can be used.
The distance d between the centers of the pair of housing parts 2 (the chemical heat-generating composition 4) in a plan view is, for example, 55mm to 90mm, more preferably 60mm to 85mm, and most preferably 65mm to 80 mm. In the case where the distance d is less than 55mm or exceeds 90mm, it may be difficult to place the receiving portion above an acupuncture point called "bitong acupuncture point" which has an effect on nasal congestion upon stimulation.
The nasal ventilation improving device 1 is enclosed in a bag (not shown) made of an air-impermeable material and hermetically stored before use. When the nasal ventilation improving device 1 is used, the nasal ventilation improving device 1 is taken out of the bag body, the peeling member 9 on the back side is peeled off, and as shown in fig. 2, the adhesive layer 8 is attached to the nose and worn. In the illustrated example, the centers of the pair of housing portions 2 (the chemical heat-generating composition 4) are disposed above the acupuncture points called "nose-passing acupuncture points".
In the nasal ventilation improving device 1 of the present embodiment configured as described above, the chemical heat-generating composition 4 is a tablet molded body, and therefore the volume of the chemical heat-generating composition 4 can be reduced. Therefore, the housing unit 2 can be miniaturized while maintaining the heat generation temperature. This can reduce the wearing area of the nasal ventilation improving device 1.
The present invention is not limited to the above-described embodiments, and various modifications can be made within the scope of the technical idea thereof. For example, although the chemical heat-generating composition 4 is accommodated between the protruding portion 6a of the front-side sheet member 6 and the back-side sheet member 7 in the above-described embodiment, as shown in fig. 3 (a), a bag member 10 having air permeability, which accommodates the chemical heat-generating composition 4 in advance, may be accommodated between the protruding portion 6a of the front-side sheet member 6 and the back-side sheet member 7. In this case, the bag member 10, the protruding portion 6a, and the back-side sheet member 7 serve as a storage portion for storing the chemical heat-generating composition 4, and the bag member 10 and the protruding portion 6a serve as a ventilation portion for bringing the chemical heat-generating composition 4 into contact with air.
As shown in fig. 3 (B), the air-permeable bag member 10 in which the chemical heat-generating composition 4 is stored in advance may be fixed by being bonded to the front-side sheet member 6 via the back-side adhesive layer 11. In this case, the bag member 10 serves as a storage portion for storing the chemical heat-generating composition 4, and the bag member 10 serves as a ventilation portion for bringing the chemical heat-generating composition 4 into contact with air. In this case, the front-side sheet member 6 and the back-side sheet member 7 may be made of an air-impermeable material.
In this case, before the nasal ventilation improving device 1 is used, a peeling member (not shown) may be attached to the adhesive layer 11 of the bag member 10, and the bag member 10 may be stored in a bag body (not shown) made of an air-impermeable material in a sealed state, and when the nasal ventilation improving device 1 is used, the bag member 10 may be taken out from the bag body, and the peeling member may be peeled off and fixed by being adhered to the front side sheet member 6.
(example 1)
The inventors of the present application evaluated the heat generation temperature of the chemical heat-generating composition 4 in relation to the nasal ventilation improving device 1 according to the present invention.
Unlike the above-described embodiment (see fig. 1), the sample S for evaluation includes 1 storage unit 2 storing the exothermic composition 4, as shown in fig. 4, and does not include the coupling portion 3 and the elastic member 5. Otherwise, since the same components as those in the above embodiment are denoted by the same reference numerals, detailed description thereof will be omitted. In the evaluation, the peeling member 9 was peeled off, and the sample S was set in the measuring apparatus via the adhesive layer 8.
The chemical exothermic composition 4 was a cylindrical tablet-shaped molded body. The pellet had a weight of 1g, a diameter of 15mm and a height of 5 mm. The chemical heating composition 4 comprises 30-40 wt% of iron powder, 1-5 wt% of salt, 20-30 wt% of water, 1-5 wt% of activated carbon powder, 10-20 wt% of a water retention material and 10-20 wt% of a temperature control agent.
The front sheet member 6 and the back sheet member 7 had a moisture permeability of 8000 g/(m)2·24h)。
The heat generation temperature (skin-side temperature) was measured for 10 samples S using a temperature measuring sensor ST-22E-005-TS3-WT4 (manufactured by Zymoo instruments) and a graphic recorder KR2S2P-NOA (manufactured by Chino Corp.). As the heat generation characteristics, the rise time (in the present example, the time from 31.5 ℃ to 39.9 ℃), the maximum temperature, and the duration (the time to be 40 ℃ or more) were measured. The results are shown in FIG. 5. In addition, with respect to the exothermic temperature with respect to time, fig. 6 shows the average value of 10 samples S.
As can be seen from fig. 5, the rise time of each sample S is within 40 seconds. As is clear from fig. 6, the time taken until the maximum temperature is reached is within 5 minutes. These times are very short compared to typical chemical warm patches. This is considered to be caused by the fact that the moisture permeability of the nonwoven fabric constituting the pouch is 8000 g/(m)224h), so that the chemical heat-generating composition rapidly comes into contact with air and the chemical heat-generating composition rapidly increases in temperature.
(example 2)
The inventors of the present invention performed a sensory test in association with the nasal ventilation improving device 1 according to the present invention.
The same sample S as used in example 1 was used in this sensory test. The subjects were 15 persons who had nasal congestion at bedtime.
The test method is as follows. The sample S was worn on the "nasal through-hole" of the face of the subject, and a commercially available product ("breathing lamp" (manufactured by GlaxoSmithKline Consumer Healthcare Japan (limited stock)) was worn on the nose of the subject.
The degree of nasal congestion of the subject was quantified by the "Visual Analogue Scale (VAS)" with the state of total nasal congestion set to 0.00 and the state of total nasal congestion set to 1.00.
The degree of nasal congestion just before wearing, 5 minutes after wearing, and 10 minutes after wearing was quantified for each of the cases of breathing through both nostrils, breathing through only the left nostril, and breathing through only the right nostril. However, when only one nostril is breathing, the one nostril is not distinguished from the other nostril, and the other nostril having a strong degree of nasal obstruction is distinguished from the other nostril having a weak degree of nasal obstruction.
The test results were processed as follows. A value obtained by subtracting the value immediately before wearing from the values after 5 minutes and 10 minutes was calculated as a value indicating the degree of improvement in nasal congestion. The calculated value is negative, and the larger the absolute value, the more nasal obstruction is improved. The graphs of the average values of the calculated values are shown in fig. 7 to 9. Fig. 7 shows a case where breathing is performed in both nostrils, fig. 8 shows a case where breathing is performed in only a single nostril having a strong nasal obstruction, and fig. 9 shows a case where breathing is performed in only a single nostril having a weak nasal obstruction. In each figure, the case where both the sample S and the commercial product were used is shown by a solid line, and the case where only the commercial product was used is shown by a broken line.
As can be seen from fig. 7 to 9, nasal congestion was improved when both the sample S and the commercial product were used together, in each of the cases where breathing was performed with both nostrils, where breathing was performed with only a single nostril having strong nasal congestion, and where breathing was performed with only a single nostril having weak nasal congestion. In particular, as can be seen from fig. 8, when breathing is performed only in a single nostril having a strong nasal obstruction degree, the nasal obstruction is improved more than when only commercially available products are used.
(description of reference numerals)
1 nasal ventilation improving device
2 housing part
3 connecting part
4 chemical exothermic composition
5 elastic member
6 front side sheet member
6a projection
7 rear surface side sheet member
d the distance between the centers of the pair of receiving parts.

Claims (3)

1. A nasal ventilation improving device, which is worn on the nose to improve nasal ventilation,
the nasal ventilation improving device comprises:
a pair of housing parts for housing the chemical heat-generating composition; and
a connecting portion for connecting the pair of receiving portions,
the chemical exothermic composition is a tablet-shaped body.
2. The nasal ventilation improving apparatus according to claim 1,
an elastic member is disposed on the connection portion, and the elastic member stretches the side wall of the nose outward when the nasal ventilation improvement device is worn.
3. The nasal ventilation improving apparatus according to claim 1 or 2,
the distance between the centers of the pair of receiving parts is 55mm to 90 mm.
CN201980041075.5A 2018-12-27 2019-12-17 Nasal ventilation improving device Pending CN112312866A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018245396A JP7296721B2 (en) 2018-12-27 2018-12-27 nasal passage improvement tool
JP2018-245396 2018-12-27
PCT/JP2019/049376 WO2020137690A1 (en) 2018-12-27 2019-12-17 Nasal congestion reliever

Publications (1)

Publication Number Publication Date
CN112312866A true CN112312866A (en) 2021-02-02

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Application Number Title Priority Date Filing Date
CN201980041075.5A Pending CN112312866A (en) 2018-12-27 2019-12-17 Nasal ventilation improving device

Country Status (6)

Country Link
JP (1) JP7296721B2 (en)
CN (1) CN112312866A (en)
AU (1) AU2019415203A1 (en)
SG (1) SG11202105673YA (en)
TW (1) TWI824078B (en)
WO (1) WO2020137690A1 (en)

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JP2023075774A (en) * 2021-11-19 2023-05-31 小林製薬株式会社 Nose permeability improvement tool

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