CN112305580A - PET detector system with self-locking structure - Google Patents

PET detector system with self-locking structure Download PDF

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Publication number
CN112305580A
CN112305580A CN202011142986.8A CN202011142986A CN112305580A CN 112305580 A CN112305580 A CN 112305580A CN 202011142986 A CN202011142986 A CN 202011142986A CN 112305580 A CN112305580 A CN 112305580A
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cross
section
self
locking
notch
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邓贞宙
周凯
唐庆
凌亮
徐思康
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Nanchang Hualiang Optoelectronics Co ltd
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Nanchang Hualiang Optoelectronics Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/20Measuring radiation intensity with scintillation detectors
    • G01T1/202Measuring radiation intensity with scintillation detectors the detector being a crystal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computerised tomographs
    • A61B6/037Emission tomography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis

Abstract

The invention discloses a PET detector system with a self-locking structure, which structurally comprises: the signal detection module conforms to the electronics module, the image reconstruction module and the power supply module. The signal detection module converts gamma photons which are driven into the crystal into visible light, performs photoelectric conversion and analog-to-digital conversion, converts the visible light into a digital electric signal and transmits the digital electric signal to the coincidence electronics module, the coincidence electronics module extracts time, energy and position information in the digital electric signal, then transmits the three information to the image reconstruction module through the Ethernet and an upper computer, and the image reconstruction module reconstructs an original image through an image reconstruction algorithm, wherein the power supply module is responsible for providing different power supplies for all devices in the electronics module. According to the invention, the self-locking structure is introduced into the self-locking photon receiving module, so that the imaging definition is effectively improved.

Description

PET detector system with self-locking structure
Technical Field
The invention relates to the field of electronic information, in particular to a PET detector system with a self-locking structure.
Background
The PET (Positron emission tomography) imaging technology is a technology utilizing tracing principle and Positron coincidence detection, and can display biological characteristics and biochemical metabolic processes of function change, cell metabolism, molecular combination, information transmission and the like of human tissues and organs at the level of histiocyte, subcellular and molecule, and can find abnormality before the occurrence of clinical symptoms and signs and the change of tissue anatomical morphology, thereby being beneficial to early diagnosis of diseases. The PET technology is applied to clinic, has very important functions in the aspects of early diagnosis and staged grading of tumors of malignant tumors, evaluation and follow-up monitoring of clinical curative effect, identification of benign and malignant lesions, assistance of decision of clinical treatment schemes and determination of target regions of radiotherapy organisms and the like, and has unique value in diagnosis of cerebrovascular diseases, neurodegenerative diseases, epilepsy and the like.
In PET imaging systems, however, a scintillation crystal is an important ring. The function of the scintillation crystal is to block incident gamma photons and absorb their energy, converting the high-energy photons, which are not visible, into low-energy visible light. In a traditional crystal array, crystal strips are all cuboid, and the crystal strips are combined together to form the array through adhesives such as optical glue and the like, so that although the crystal strips are fixed together, gaps still exist between the crystal strips, light yield is low, spatial and temporal resolution of a corresponding system is low, and the final imaging effect is greatly influenced.
Therefore, there is a need to improve the existing crystal structure to overcome the above-mentioned drawbacks in the prior art in view of the above-mentioned problems in the scintillation crystal.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention aims to provide a PET detector system with a self-locking structure, which solves the problems of the prior art, and the invention adopts the following technical scheme for achieving the purpose:
preferably, a PET detector system of a self-locking structure, the structure comprising: the signal detection module, the front-end electronics module, the coincidence electronics module, the image reconstruction module and the power module are characterized by comprising
The signal detection module comprises a self-locking photon receiving module and a front-end electronic module, wherein the self-locking photon receiving module is used for performing energy precipitation on gamma photons striking on the crystal and converting the gamma photons into visible light to be transmitted to the front-end electronic module; the front-end electronics module is coupled with the self-locking photon receiving module through light guide, performs photoelectric conversion and analog-to-digital conversion on the transmitted visible light, converts the visible light into a digital electric signal and then transmits the digital electric signal to the coincidence electronics module;
the coincidence electronics module is used for extracting time, energy and position information in the digital electric signal output by the front-end electronics module, and then transmitting the three information to the image reconstruction module through the Ethernet and the upper computer;
the image reconstruction module reconstructs an original image by using time, energy and position information through an image reconstruction algorithm;
and the power supply module is responsible for providing different power supplies for all devices in the electronic module.
Preferably, the self-locking photon receiving module consists of a self-locking crystal unit 111, a self-locking crystal unit 112, a self-locking crystal unit 113, a self-locking crystal unit 114, a self-locking crystal unit 115, a self-locking crystal unit 116, a self-locking crystal unit 117, a self-locking crystal unit 118 and a self-locking crystal unit 119, wherein each crystal unit is formed by removing a plurality of notches from one crystal, wherein
The length of the self-locking crystal unit 111 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 101 is 2 cross sections, the width is 1 cross section, and the height is 0.5 cross section; notch 102 is 1 cross-section long, 0.5 cross-sections wide, and 0.5 cross-sections high;
the length of the self-locking crystal unit 112 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 201 is 0.5 cross section, the width is 1 cross section, and the height is 0.5 cross section; notch 202 is 0.5 cross sections long, 1 cross section wide, and 0.5 cross sections tall; notch 203 is 1 cross section long, 0.5 cross section wide and 1 cross section high;
self-locking crystal unit 113 is 4 cross sections in length, 1 cross section in width and height, wherein notch 301 is 1 cross section in length, 1 cross section in width and 0.5 cross section in height;
the length of the self-locking crystal unit 114 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 401 is 1 cross section, the width is 1 cross section, and the height is 0.5 cross section; notch 402 is 0.5 cross-sections long, 0.5 cross-sections wide, and 1 cross-section tall;
the length of the self-locking crystal unit 115 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 501 is 1 cross section, the width is 0.5 cross section, and the height is 0.5 cross section; notch 502 is 1.5 cross sections long, 0.5 cross sections wide, and 1 cross section tall; the recess 503 has 0.5 cross-sections in length, 1 cross-section in width, and 0.5 cross-section in height;
the length of the self-locking crystal unit 116 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 601 is 1.25 cross sections, the width is 1 cross section, and the height is 0.5 cross section; notch 602 has 0.25 cross-sections long, 0.5 cross-sections wide, and 0.5 cross-sections high; notch 603 is 0.25 cross sections long, 1 cross section wide, and 0.5 cross sections tall; notch 604 is 0.5 cross-sections long, 0.5 cross-sections wide, and 1 cross-section high;
the length of the self-locking crystal unit 117 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 701 is 0.75 cross section, the width is 0.5 cross section, and the height is 0.5 cross section; notch 702 is 1 cross-section long, 0.5 cross-sections wide, and 1 cross-section high;
the length of the self-locking crystal unit 118 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 801 is 1 cross section, the width is 1 cross section, and the height is 0.5 cross section; notch 802 is 0.5 cross-sections long, 1 cross-section wide, and 0.5 cross-sections tall;
the self-locking crystal unit 119 is 4 cross sections in length and 1 cross section in width and height, wherein the notch 901 is 1 cross section in length, 1 cross section in width and 0.5 cross section in height.
Preferably, the front-end electronics module is composed of a photoelectric conversion unit, a pre-amplification unit, a gain adjustment unit and an ADC unit.
Preferably, the coincidence electronics module is composed of an FPGA unit, a PET information unit, an upper computer unit and an ethernet data transmission unit.
Preferably, the image reconstruction module adopts an analytical method and an iterative method.
Preferably, the power module needs to provide 5 different power supplies, which are ± 5V, 3.3V, 1.8V and 1.2V respectively.
Preferably, the self-locking photon receiving module consists of 9 crystals with completely different shapes, and the combination mode is that
S1, first, self-locking crystal units 113 and 114 are adjacent, wherein notch 301 in self-locking crystal unit 113 is opposite to notch 401 in self-locking crystal unit 114 to form a hollow cube with a length, width and height both having a cross section;
s2 then self-locking crystal unit 116 is connected 604 to 113 with notch 601 in self-locking crystal unit 116 connected to notch 402 in self-locking crystal unit 114;
s3 then the notch 801 of the self-locking crystal unit 118 is snapped into engagement with the self-locking crystal unit 114;
s4 then connecting self-locking crystal units 117 with 113 and 116;
s5 then self-locking crystal units 115 and 116 are opposed, and notch 501 is connected to crystal bars of self-locking crystal units 113 and 114;
s6 then the self-locking crystal units 111 and 114 are faced and simultaneously clamped in connection with the notch 802 of the self-locking crystal unit 118;
s7 finally, 203 of the crystal unit 112 is connected to 901 of the crystal unit 119 and inserted into a cross-shaped hollow cube having a length, a width and a height both of which are cross-sectional to form a complete crystal unit.
Preferably, the pre-amplification circuit in the front-end electronics module adopts a voltage sensitive circuit, a charge sensitive circuit and a current sensitive circuit.
Preferably, the FPGA unit in the coincidence electronics module controls the digital-to-analog conversion chip to realize circuit gain adjustment, and simultaneously, the signal output by the ADC is operated to obtain time, energy and position information of a single event.
Preferably, the system is constructed in a self-locking PET detector system as follows,
s1, firstly, starting a power supply module to provide different power supplies for each device in an electronics module;
s2, then the self-locking photon receiving module absorbs gamma photons from the outside and converts the gamma photons into visible light;
s3, receiving the visible light by using a front-end electronic module and performing analog-to-digital conversion on the optical signal to obtain an electric signal;
s4, extracting time, energy and position information in the electric signal through a coincidence electronics module;
and S5, reconstructing the original image by the final image reconstruction module through three kinds of information in the electric signals.
The invention has the beneficial effects that:
on the premise of ensuring the imaging effect of the system, the invention changes the shape structure of the self-locking crystal unit in the self-locking photon receiving module and reduces the distance between the crystal strips, thereby enabling more gamma photons to be absorbed by the crystal, increasing the light yield, improving the spatial resolution and the position resolution and improving the final imaging quality. In addition, the self-locking structure of the crystal strip enables the crystal array to be deformed to a certain extent, and the external force resistance of the system is improved.
Drawings
Fig. 1 is a schematic structural diagram of a self-locking PET detector system according to an embodiment of the present invention.
FIG. 2 is an image of a control experiment according to an embodiment of the present invention.
FIG. 3 is a schematic diagram of a single self-locking crystal unit structure of the present invention.
Fig. 4 is a schematic structural diagram of two self-locking photon receiving modules according to an embodiment of the present invention.
Detailed Description
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
In an embodiment, a PET detector system of a self-locking configuration, the configuration comprising: the signal detection module accords with four modules of electronics module, image reconstruction module and power module, wherein:
the signal detection module is used for detecting gamma high-energy photons and mainly comprises a self-locking photon receiving module and a front-end electronics module, wherein the self-locking photon receiving module comprises a scintillation crystal, the scintillation crystal is taken as one of main materials in the current high-energy photon absorption material industry, and the signal detection module has the advantages of high luminous intensity, high density, high attenuation speed, high corresponding speed, good stability along with temperature change and the like. In this example, the scintillation crystal employed is LaCl3Compared with cerium-doped lanthanum chloride crystals of other halogen elements, the Ce (cerium-doped lanthanum chloride) crystal has stronger LaCl3: Ce density and gamma photon interception capability, and obviously more excellent comprehensive scintillation property. Also, in this example, we used two sets of LaCl with equal volumes of AB but different combined shapes by control experiments3Ce crystal array is used to illustrate the advantages of the crystal array with the self-locking structure. In group A, the crystal array adopts a self-locking structure, namely a self-locking photon receiving module is formed by 9 self-locking crystal units, which comprises the following specific steps:
the length of the self-locking crystal unit 111 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 101 is 2 cross sections, the width is 1 cross section, and the height is 0.5 cross section; notch 102 is 1 cross-section long, 0.5 cross-section wide, and 0.5 cross-section high, wherein 1 cross-section is 1 cm and is shaped as 310 in fig. 3;
the length of the self-locking crystal unit 112 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 201 is 0.5 cross section, the width is 1 cross section, and the height is 0.5 cross section; notch 202 is 0.5 cross sections long, 1 cross section wide, and 0.5 cross sections tall; the notch 203 is 1 cross section long, 0.5 cross section wide and 1 cross section high, wherein 1 cross section is 1 cm and is 320 in fig. 3;
self-locking crystal unit 113 is 4 cross sections in length, 1 cross section in width and height, wherein notch 301 is 1 cross section in length, 1 cross section in width and 0.5 cross section in height, wherein 1 cross section is 1 cm, and the shape is 330 in fig. 3;
the length of the self-locking crystal unit 114 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 401 is 1 cross section, the width is 1 cross section, and the height is 0.5 cross section; notch 402 is 0.5 cross-sections long, 0.5 cross-sections wide, and 1 cross-section tall, 1 cross-section of which is 1 cm in length and is 340 in fig. 3;
the length of the self-locking crystal unit 115 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 501 is 1 cross section, the width is 0.5 cross section, and the height is 0.5 cross section; notch 502 is 1.5 cross sections long, 0.5 cross sections wide, and 1 cross section tall; the recess 503 has a length of 0.5 cross-section, a width of 1 cross-section, and a height of 0.5 cross-section, wherein 1 cross-section is 1 cm, and is 350 in fig. 3;
the length of the self-locking crystal unit 116 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 601 is 1.25 cross sections, the width is 1 cross section, and the height is 0.5 cross section; notch 602 has 0.25 cross-sections long, 0.5 cross-sections wide, and 0.5 cross-sections high; notch 603 is 0.25 cross sections long, 1 cross section wide, and 0.5 cross sections tall; notch 604 is 0.5 cross-sections long, 0.5 cross-sections wide, and 1 cross-section tall, 1 cross-section of which is 1 centimeter and is 360 in fig. 3;
the length of the self-locking crystal unit 117 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 701 is 0.75 cross section, the width is 0.5 cross section, and the height is 0.5 cross section; notch 702 is 1 cross-section long, 0.5 cross-sections wide, and 1 cross-section tall, 1 cross-section of which is 1 centimeter and is shaped as 370 in fig. 3;
the length of the self-locking crystal unit 118 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 801 is 1 cross section, the width is 1 cross section, and the height is 0.5 cross section; notch 802 is 0.5 cross-sections long, 1 cross-section wide, and 0.5 cross-section tall, wherein 1 cross-section is 1 cm and is 380 in fig. 3;
the self-locking crystal unit 119 is 4 cross-sections in length, 1 cross-section in width and height, wherein the recess 901 is 1 cross-section in length, 1 cross-section in width and 0.5 cross-section in height, wherein 1 cross-section is 1 cm, and the shape is 390 in fig. 3.
The 9 self-locking crystal units form a self-locking photon receiving module according to the following combination mode,
s1, first, self-locking crystal units 113 and 114 are adjacent, wherein notch 301 in self-locking crystal unit 113 is opposite to notch 401 in self-locking crystal unit 114 to form a hollow cube with a length, width and height both having a cross section;
s2 then self-locking crystal unit 116 is connected 604 to 113 with notch 601 in self-locking crystal unit 116 connected to notch 402 in self-locking crystal unit 114;
s3 then the notch 801 of the self-locking crystal unit 118 is snapped into engagement with the self-locking crystal unit 114;
s4 then connecting self-locking crystal units 117 with 113 and 116;
s5 then self-locking crystal units 115 and 116 are opposed, and notch 501 is connected to crystal bars of self-locking crystal units 113 and 114;
s6 then the self-locking crystal units 111 and 114 are faced and simultaneously clamped in connection with the notch 802 of the self-locking crystal unit 118;
s7 finally, 203 of the crystal unit 112 is connected to 901 of the crystal unit 119 and inserted into a cross-shaped hollow cube having a length, width and height that are both a cross-section, to form a complete crystal unit, which is 4001 in fig. 4.
In group B, the self-locking photon receiving module is composed of 6 × 6 cubic crystal strips with length of 1 cm and width and height of 0.88 cm, and the shape is 4002 in FIG. 4.
For the two groups of front-end electronic modules, the coincidence electronic module, the image reconstruction module and the power supply module all adopt the same equipment, in particular,
the two groups of front-end electronic modules are shown in figure 1, and the visible light coming out of the crystal is subjected to photoelectric conversion by using a photomultiplier tube, and then the converted electric signals are amplified and pass through an operational amplifier. Because differential processing is used during signal transmission, and the operational circuit adopts a voltage sensitive circuit, a charge sensitive circuit and a current sensitive circuit, the amplifier is a differential voltage sensitive circuit, a differential charge sensitive circuit and a differential current sensitive circuit. Meanwhile, due to the difference of the light output of the self-locking crystal unit and the gain inconsistency of different positions of the photomultiplier, a gain adjusting unit needs to be added behind the operational amplifier to improve the dynamic range and the precision of the system. Finally, an ADC unit, in this embodiment an 8-channel ADC, is used.
As shown in fig. 1, the two groups of coincidence electronic modules firstly adopt the FPGA unit to extract time, energy and position information in the digitized scintillation pulse signal, then the three types of information are registered and packaged by the PET information unit and are sent to the ethernet data transmission unit 230, and the ethernet data transmission unit 230 adopts the embedded ethernet control chip to realize information transmission between the PET information unit and the upper computer unit 240.
The two sets of image reconstruction modules 300 are shown in fig. 1, and in this embodiment, the OSEM (split into ordered subsets to maximize the expected value) algorithm is used to obtain the final imaging result by iterating 100 times, as shown in fig. 2.
Two sets of power modules 400 are shown in fig. 1. in this embodiment, the power modules 400 provide 5 different power supplies, i.e., ± 5V, 3.3V, 1.8V, and 1.2V, respectively. The operational amplifier is supplied with +/-5V, the reference voltage source in the ADC unit is supplied with 3.3V, the analog-to-digital conversion ADC in the ADC unit is supplied with 1.8V, and the FPGA is supplied with 1.2V.
From the two imaging graphs of fig. 2, it can be seen that the imaging result 2001 of the PET system using the group a crystal array with the self-locking structure is significantly better than that of the group B2002 under the same conditions of other experimental facilities.
Finally, only specific embodiments of the present invention have been described in detail above. The invention is not limited to the specific embodiments described above. Equivalent modifications and substitutions by those skilled in the art are also within the scope of the present invention. Accordingly, equivalent alterations and modifications are intended to be included within the scope of the invention, without departing from the spirit and scope of the invention.

Claims (10)

1. A PET detector system of a self-locking construction, the construction comprising: a signal detection module, a front-end electronics module, a coincidence electronics module, an image reconstruction module and a power supply module, wherein
The signal detection module comprises a self-locking photon receiving module and a front-end electronic module, wherein the self-locking photon receiving module is used for performing energy precipitation on gamma photons striking on the crystal and converting the gamma photons into visible light to be transmitted to the front-end electronic module; the front-end electronics module is coupled with the self-locking photon receiving module through light guide, performs photoelectric conversion and analog-to-digital conversion on the transmitted visible light, converts the visible light into a digital electric signal and then transmits the digital electric signal to the coincidence electronics module;
the coincidence electronics module is used for extracting time, energy and position information in the digital electric signal output by the front-end electronics module, and then transmitting the three information to the image reconstruction module through the Ethernet and the upper computer;
the image reconstruction module reconstructs an original image by using time, energy and position information through an image reconstruction algorithm;
and the power supply module is responsible for providing different power supplies for all devices in the electronic module.
2. The PET detector system with a self-locking structure of claim 1, wherein the self-locking photon receiving module is composed of a self-locking crystal unit 111, a self-locking crystal unit 112, a self-locking crystal unit 113, a self-locking crystal unit 114, a self-locking crystal unit 115, a self-locking crystal unit 116, a self-locking crystal unit 117, a self-locking crystal unit 118 and a self-locking crystal unit 119, each crystal unit is a crystal with a plurality of notches removed, and the notches are formed in the crystal unit
The length of the self-locking crystal unit 111 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 101 is 2 cross sections, the width is 1 cross section, and the height is 0.5 cross section; notch 102 is 1 cross-section long, 0.5 cross-sections wide, and 0.5 cross-sections high;
the length of the self-locking crystal unit 112 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 201 is 0.5 cross section, the width is 1 cross section, and the height is 0.5 cross section; notch 202 is 0.5 cross sections long, 1 cross section wide, and 0.5 cross sections tall; notch 203 is 1 cross section long, 0.5 cross section wide and 1 cross section high;
self-locking crystal unit 113 is 4 cross sections in length, 1 cross section in width and height, wherein notch 301 is 1 cross section in length, 1 cross section in width and 0.5 cross section in height;
the length of the self-locking crystal unit 114 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 401 is 1 cross section, the width is 1 cross section, and the height is 0.5 cross section; notch 402 is 0.5 cross-sections long, 0.5 cross-sections wide, and 1 cross-section tall;
the length of the self-locking crystal unit 115 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 501 is 1 cross section, the width is 0.5 cross section, and the height is 0.5 cross section; notch 502 is 1.5 cross sections long, 0.5 cross sections wide, and 1 cross section tall; the recess 503 has 0.5 cross-sections in length, 1 cross-section in width, and 0.5 cross-section in height;
the length of the self-locking crystal unit 116 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 601 is 1.25 cross sections, the width is 1 cross section, and the height is 0.5 cross section; notch 602 has 0.25 cross-sections long, 0.5 cross-sections wide, and 0.5 cross-sections high; notch 603 is 0.25 cross sections long, 1 cross section wide, and 0.5 cross sections tall; notch 604 is 0.5 cross-sections long, 0.5 cross-sections wide, and 1 cross-section high;
the length of the self-locking crystal unit 117 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 701 is 0.75 cross section, the width is 0.5 cross section, and the height is 0.5 cross section; notch 702 is 1 cross-section long, 0.5 cross-sections wide, and 1 cross-section high;
the length of the self-locking crystal unit 118 is 4 cross sections, the width and the height are 1 cross section, wherein the length of the notch 801 is 1 cross section, the width is 1 cross section, and the height is 0.5 cross section; notch 802 is 0.5 cross-sections long, 1 cross-section wide, and 0.5 cross-sections tall;
the self-locking crystal unit 119 is 4 cross sections in length and 1 cross section in width and height, wherein the notch 901 is 1 cross section in length, 1 cross section in width and 0.5 cross section in height.
3. The self-locking PET detector system of claim 1, wherein the front-end electronics module is composed of a photoelectric conversion unit, a preamplifier unit, a gain adjustment unit and an ADC unit.
4. The self-locking PET detector system of claim 1, wherein the coincidence electronics module is composed of an FPGA unit, a PET information unit, an upper computer unit and an Ethernet data transmission unit.
5. The self-locking PET detector system of claim 1 wherein the image reconstruction module employs analytical and iterative methods.
6. The self-locking PET detector system of claim 1, wherein the power module is required to provide 5 different power supplies, i.e., + -5V, 3.3V, 1.8V and 1.2V.
7. The self-locking PET detector system of claim 1, wherein the self-locking photon receiving module is composed of 9 crystals with completely different shapes, and the combination is S1 that the self-locking crystal units 113 and 114 are adjacent to each other, wherein the notch 301 of the self-locking crystal unit 113 and the notch 401 of the self-locking crystal unit 114 are opposite to each other to form a hollow cube with a length, width and height of each cross section;
s2 then self-locking crystal unit 116 is connected 604 to 113 with notch 601 in self-locking crystal unit 116 connected to notch 402 in self-locking crystal unit 114;
s3 then the notch 801 of the self-locking crystal unit 118 is snapped into engagement with the self-locking crystal unit 114;
s4 then connecting self-locking crystal units 117 with 113 and 116;
s5 then self-locking crystal units 115 and 116 are opposed, and notch 501 is connected to crystal bars of self-locking crystal units 113 and 114;
s6 then the self-locking crystal units 111 and 114 are faced and simultaneously clamped in connection with the notch 802 of the self-locking crystal unit 118;
s7 finally, 203 of the crystal unit 112 is connected to 901 of the crystal unit 119 and inserted into a cross-shaped hollow cube having a length, a width and a height both of which are cross-sectional to form a complete crystal unit.
8. The front-end electronics module of claim 3, wherein the pre-amplification circuitry in the front-end electronics module employs voltage-sensitive circuitry, charge-sensitive circuitry, and current-sensitive circuitry.
9. The coincidence electronics module of claim 4, wherein the FPGA unit in the coincidence electronics module controls the digital-to-analog conversion chip to achieve circuit gain adjustment, and operates the signal output by the ADC to obtain time, energy and position information of a single event.
10. The self-locking PET detector system of claim 1, wherein the system is constructed by the following method,
s1, firstly, turning on the power module to provide different power supplies for each device in the electronic module;
s2, then the self-locking photon receiving module absorbs gamma photons from the outside and converts the gamma photons into visible light;
s3, receiving the visible light by using a front-end electronic module and performing analog-to-digital conversion on the optical signal to obtain an electric signal;
s4, extracting time, energy and position information in the electric signal through a coincidence electronics module;
and S5, reconstructing the original image by the final image reconstruction module through three kinds of information in the electric signals.
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Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000657A1 (en) * 1990-07-02 1992-01-09 Varian Associates, Inc. Method for increasing the accuracy of a radiation therapy apparatus
US20090132789A1 (en) * 2007-10-08 2009-05-21 Naresh Kesavan Rao Apparatus and method for channel-specific configuration in a readout asic
CN102178542A (en) * 2011-04-02 2011-09-14 苏州瑞派宁科技有限公司 Positron emission tomography imaging frame with variable structure
CN106805990A (en) * 2015-12-02 2017-06-09 沈阳东软医疗系统有限公司 A kind of RT-CT integrated equipments
CN107468269A (en) * 2017-09-18 2017-12-15 南京瑞派宁信息科技有限公司 A kind of positron emission tomography device and method
CN108324308A (en) * 2018-03-22 2018-07-27 苏州瑞迈斯医疗科技有限公司 A kind of number PET system
CN108453651A (en) * 2018-05-24 2018-08-28 明峰医疗系统股份有限公司 A kind of pet detector axis positioning tool
CN109669206A (en) * 2019-03-03 2019-04-23 南昌华亮光电有限责任公司 Circulating type liquid scintillator intelligence energy disperse spectroscopy system and its signal processing method
CN109683188A (en) * 2019-01-15 2019-04-26 南昌大学 A kind of Qi Liankefu event and gamma events meet imaging device and method
CN110967724A (en) * 2019-12-27 2020-04-07 南昌大学 Self-locking PET detector
CN110974267A (en) * 2019-11-28 2020-04-10 南昌大学 PET detector of composite crystal array and construction method thereof
EP3646793A2 (en) * 2018-10-18 2020-05-06 MedPhoton GmbH Mobile imaging ring system
CN111208548A (en) * 2019-12-02 2020-05-29 南昌大学 Double-material PET imaging system and method
CN111528888A (en) * 2020-04-30 2020-08-14 南昌大学 Single photon emission tomography structure based on self-locking structure luminescent crystal

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000657A1 (en) * 1990-07-02 1992-01-09 Varian Associates, Inc. Method for increasing the accuracy of a radiation therapy apparatus
US20090132789A1 (en) * 2007-10-08 2009-05-21 Naresh Kesavan Rao Apparatus and method for channel-specific configuration in a readout asic
CN102178542A (en) * 2011-04-02 2011-09-14 苏州瑞派宁科技有限公司 Positron emission tomography imaging frame with variable structure
CN106805990A (en) * 2015-12-02 2017-06-09 沈阳东软医疗系统有限公司 A kind of RT-CT integrated equipments
CN107468269A (en) * 2017-09-18 2017-12-15 南京瑞派宁信息科技有限公司 A kind of positron emission tomography device and method
CN108324308A (en) * 2018-03-22 2018-07-27 苏州瑞迈斯医疗科技有限公司 A kind of number PET system
CN108453651A (en) * 2018-05-24 2018-08-28 明峰医疗系统股份有限公司 A kind of pet detector axis positioning tool
EP3646793A2 (en) * 2018-10-18 2020-05-06 MedPhoton GmbH Mobile imaging ring system
CN109683188A (en) * 2019-01-15 2019-04-26 南昌大学 A kind of Qi Liankefu event and gamma events meet imaging device and method
CN109669206A (en) * 2019-03-03 2019-04-23 南昌华亮光电有限责任公司 Circulating type liquid scintillator intelligence energy disperse spectroscopy system and its signal processing method
CN110974267A (en) * 2019-11-28 2020-04-10 南昌大学 PET detector of composite crystal array and construction method thereof
CN111208548A (en) * 2019-12-02 2020-05-29 南昌大学 Double-material PET imaging system and method
CN110967724A (en) * 2019-12-27 2020-04-07 南昌大学 Self-locking PET detector
CN111528888A (en) * 2020-04-30 2020-08-14 南昌大学 Single photon emission tomography structure based on self-locking structure luminescent crystal

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