CN112294305A - Physiological signal sensing device - Google Patents
Physiological signal sensing device Download PDFInfo
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- CN112294305A CN112294305A CN202010314695.6A CN202010314695A CN112294305A CN 112294305 A CN112294305 A CN 112294305A CN 202010314695 A CN202010314695 A CN 202010314695A CN 112294305 A CN112294305 A CN 112294305A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/22—Arrangements of medical sensors with cables or leads; Connectors or couplings specifically adapted for medical sensors
- A61B2562/225—Connectors or couplings
- A61B2562/227—Sensors with electrical connectors
Abstract
A physiological signal sensing device comprises a sensing piece and a transmitter. The sensing part is provided with a signal detection end used for being implanted under the skin of a living body to measure an analyte and a signal output end used for outputting a detection signal, the transmitter is connected with the sensing part and used for receiving the detection signal and outputting a corresponding physiological parameter, the transmitter comprises a circuit board with a plurality of electric contacts and a port connected with the circuit board, the port comprises a jack communicated with the circuit board and a plurality of conductive pieces, wherein the sensing part is inserted in the jack, one side of each conductive piece is electrically connected with the corresponding electric contact, the other side of each conductive piece is electrically contacted with the signal output end, so that the sensing part is electrically connected with the circuit board, and the conductive pieces can movably contact with the sensing part along with the insertion and extraction of the sensing part in the jack to ensure that the sensing part is effectively contacted with the conductive spring, to stabilize the transmission signal.
Description
Technical Field
The present invention relates to a sensing device, and more particularly, to a physiological signal sensing device.
Background
Referring to fig. 23, there is a sensing device 900 disclosed in U.S. Pat. No. 7899511B2, which includes a sheet-shaped adhesive 91 for adhering to the skin of a user, a base 92 attached to the sheet-shaped adhesive, a sensor 93 mounted on the base, and a transmitter 94 disposed on the base 92 and connected to the sensor 93. The sensor is configured to be implanted in the subcutaneous tissue of the user to sense a physiological signal of the user, and the transmitter 94 transmits the sensed physiological signal to a receiver (not shown). The sensing device 900 is installed by adhering the sheet-shaped adhesive 91 to the skin of the user, then installing the sensor 93 to the base 92 by an implanter (not shown) and partially implanting the sensor under the skin of the user, and finally covering the emitter 94 on the base 92 and electrically connecting the sensor 93.
Referring to fig. 24, the sensor 93 mainly includes a fixing base 931, a sensing element 932 fixed to the fixing base 931 and having an elongated shape, and two contact heads 933 fixed to the fixing base 931 and contacting the sensing element 932, when the emitter 94 is covered on the base 92, a contact (not shown) at the bottom of the emitter 94 contacts the contact heads 933, so that the sensing element 932 is electrically connected to the emitter 94. However, the contact 933 is connected to the emitter 94 and the sensing element 932 in a vertical direction, so the thickness of the contact 933 cannot be smaller than the distance between the emitter 94 and the sensing element 932, and the overall thickness of the sensing device 900 is limited, which makes it difficult to achieve the thin-type object. In addition, the contact 933 is liable to be unable to be accurately and reliably connected to the transmitter 94 when being closed due to manufacturing errors or alignment errors, and thus signal transmission between the sensor 93 and the transmitter 94 is affected.
Disclosure of Invention
It is an object of the present invention to provide a physiological signal sensing device that addresses at least one of the shortcomings of the background art.
The invention relates to a physiological signal sensing device for measuring a physiological parameter of an analyte in a living body, which comprises a sensing element and a transmitter. The sensing element has a signal output end and a signal detection end, wherein the signal detection end is implanted under the skin of the organism to measure a detection signal of the analyte of the organism, and the signal output end is used for outputting the detection signal. The transmitter is connected with the sensing piece, is used for receiving the detection signal and outputting physiological parameters corresponding to the analyte after operation, and comprises a circuit board and a port. The circuit board is provided with a plurality of electrical contacts. The port is connected with the circuit board and is provided with a jack communicated with the circuit board and a plurality of steel balls accommodated in the port. The sensing piece is inserted in the jack, one side of each steel ball is electrically connected with the respective electrical contact of the circuit board, and the signal output end of the sensing piece is electrically contacted with the other side of the steel ball, so that the signal output end of the sensing piece is electrically connected with the electrical contact of the circuit board by using the steel ball, and the steel ball can be movably contacted with the sensing piece along with the insertion and extraction of the sensing piece into and out of the jack.
The invention also provides a physiological signal sensing device for measuring a physiological parameter of an analyte in a living body, comprising a sensing element and a transmitter. The sensing element has a signal output end and a signal detection end, wherein the signal detection end is implanted under the skin of the organism to measure a detection signal of the analyte of the organism, and the signal output end is used for outputting the detection signal. The transmitter is connected with the sensing piece, is used for receiving the detection signal and outputting physiological parameters corresponding to the analyte after operation, and comprises a circuit board and a port. The circuit board is provided with a plurality of electrical contacts. The port is connected with the circuit board and is provided with a jack communicated with the circuit board and a plurality of steel rings accommodated in the port. The sensing piece is inserted into the jack, one side of each steel ring is electrically connected with the respective electrical contact of the circuit board, and the signal output end of the sensing piece is electrically contacted with the other side of the steel ring, so that the signal output end of the sensing piece is electrically connected with the electrical contact of the circuit board by the steel ring, and the steel ring can be movably contacted with the sensing piece along with the insertion and extraction of the sensing piece into and out of the jack.
According to the physiological signal sensing device, the port further comprises a shell which is arranged on the bottom surface of the circuit board and is provided with the jack, and a plurality of accommodating grooves which are communicated with the jack, wherein the accommodating grooves are used for accommodating the steel balls respectively.
According to the physiological signal sensing device, the port further comprises a plurality of elastic bodies, and the elastic bodies are respectively arranged between the shell and the steel balls.
According to the physiological signal sensing device, the steel ball of the port is positioned on one side of the jack.
According to the physiological signal sensing device, the steel balls at the ports are positioned on two opposite sides of the jack.
In the physiological signal sensing device, one side of each steel ball, which is contacted with the respective electrical contact, and the other side of each steel ball, which is contacted with the signal output end, are positioned in two different axial directions.
The physiological signal sensing device of the invention is characterized in that the port is provided with a plurality of metal elastic sheets which are respectively connected with the electrical contacts and enable the steel balls to be pressed towards the direction of the sensing element, one side of each steel ball is contacted with the respective metal elastic sheet so as to be electrically connected with the respective electrical contact, and the side of each steel ball contacted with each metal elastic sheet and the other side contacted with the signal output end are positioned on the same axial direction.
In the physiological signal sensing device, the sensing element is inserted into the jack along the first axial direction, and the signal output end of the sensing element is electrically contacted with each steel ball along the second axial direction.
The physiological signal sensing device also comprises a fixed seat, and the sensing part is arranged on the fixed seat.
The physiological signal sensing device also comprises a base which can be separately assembled on the emitter, the fixing base is accommodated between the emitter and the base, and the signal detection end of the sensing piece protrudes out of the bottom surface of the fixing base.
According to the physiological signal sensing device, the port further comprises a shell which is arranged on the bottom surface of the circuit board and is provided with the jack, and a plurality of accommodating grooves which are communicated with the jack, wherein the accommodating grooves are respectively used for accommodating the steel ring.
According to the physiological signal sensing device, the port further comprises a plurality of elastic bodies, and the elastic bodies are respectively arranged between the shell and the steel ring.
According to the physiological signal sensing device, the steel ring of the port is positioned on one side of the jack.
According to the physiological signal sensing device, the steel rings of the ports are positioned on two opposite sides of the jack.
In the physiological signal sensing device, one side of each steel ring, which is contacted with the respective electrical contact, and the other side of each steel ring, which is contacted with the signal output end, are positioned in two different axial directions.
In the physiological signal sensing device, the port is provided with a plurality of metal elastic sheets which are respectively connected with the electrical contacts and enable the steel rings to be pressed towards the direction of the sensing piece, one side of each steel ring is contacted with the respective metal elastic sheet so as to be electrically connected with the respective electrical contact, and the contact side of each steel ring and each metal elastic sheet and the contact side of each steel ring and the signal output end are positioned on the same axial direction.
In the physiological signal sensing device, the sensing part is inserted into the insertion hole along the first axial direction, and the signal output end of the sensing part is electrically contacted with each steel ring along the second axial direction.
The physiological signal sensing device also comprises a fixed seat, and the sensing part is arranged on the fixed seat.
The physiological signal sensing device also comprises a base which can be separately assembled on the emitter, the fixing base is accommodated between the emitter and the base, and the signal detection end of the sensing piece protrudes out of the bottom surface of the fixing base.
The invention has the beneficial effects that: the steel ball or the steel ring can be movably contacted with the sensing piece along with the insertion and the extraction of the sensing piece, so that the sensing piece can be ensured to be effectively contacted with the conductive spring, signals can be stably transmitted between the sensing piece and the circuit board, the insertion resistance of the sensing piece can be reduced, and the use smoothness is increased.
Drawings
Other features and effects of the present invention will become apparent from the following detailed description of the embodiments with reference to the accompanying drawings, in which:
FIG. 1 is a perspective view of a first embodiment of a physiological signal sensing device of the present invention;
FIG. 2 is an exploded perspective view of the first embodiment;
FIG. 3 is an exploded perspective view of the emitter of the first embodiment;
fig. 4 is an exploded perspective view of a bottom housing and a port in the emitter of a variation of the first embodiment;
FIG. 5 is an enlarged view of a portion of the variation of FIG. 4;
FIG. 6 is a cross-sectional view taken along line VI-VI in FIG. 1;
FIG. 7 is a perspective cross-sectional view of the first embodiment;
FIG. 8 is a partial cross-sectional view of another variation of the first embodiment;
FIG. 9 is a partial cross-sectional view of another variation of the first embodiment;
FIG. 10 is a schematic circuit diagram of the transmitter of the first embodiment not yet combined with a sensing element;
FIG. 11 is a schematic electrical circuit diagram of the first embodiment of the emitter in combination with the sensing element;
FIG. 12 is a circuit schematic of a variation of the first embodiment;
FIG. 13 is a circuit schematic of another variation of the first embodiment;
FIG. 14 is a circuit schematic of yet another variation of the first embodiment;
FIG. 15 is a cross-sectional view of a second embodiment of the physiological signal sensing device of the present invention;
FIG. 16 is an enlarged partial view of FIG. 15;
FIG. 17 is a partial cross-sectional view of a third embodiment of a physiological signal sensing device of the present invention;
FIG. 18 is a partial cross-sectional view of a fourth embodiment of the physiological signal sensing device of the present invention;
FIG. 19 is a partial cross-sectional view of a variation of the fourth embodiment;
FIG. 20 is a partial cross-sectional view of another variation of the fourth embodiment;
FIG. 21 is a cross-sectional view of a variation of the first embodiment;
FIG. 22 is a cross-sectional view of a variation of the second embodiment;
fig. 23 is an exploded perspective view of a conventional sensing device; and
fig. 24 is an exploded perspective view of a sensor of the conventional sensing device.
Detailed Description
Before the present invention is described in detail, it should be noted that in the following description, similar components are denoted by the same reference numerals.
In addition, the terms "upper", "lower", "top", "bottom", and "bottom" used in the description of the present invention are used for convenience only to indicate relative orientations between elements, and do not limit the actual directions in which the respective elements are used.
Referring to fig. 1 to 7, a first embodiment of the physiological signal sensing device of the present invention is adapted to be mounted on a skin surface of a living body (not shown) and used for measuring an analyte in the living body, in this embodiment, glucose, and measuring a glucose concentration in Interstitial fluid (ISF) of a human body, but in other embodiments, the analyte is not limited thereto.
Referring to fig. 1 and 2, a first axial direction D1 and a second axial direction D2 are defined, the first axial direction D1 and the second axial direction D2 are perpendicular in the present embodiment, but the included angle between the first axial direction D1 and the second axial direction D2 is not limited to 90 ° in other embodiments. The physiological signal sensing device comprises a base 1 arranged on the skin surface of the living body, a sensor 2 arranged on the base 1 and used for being implanted into the living body, and a Transmitter 3(Transmitter) which is detachably arranged on the base 1 along the first axial direction D1 and connected with the sensor 2. The sensor 2 is used for measuring the analyte in the living body and transmitting a physiological signal corresponding to the data of the analyte to the transmitter 3, and the transmitter 3 is used for transmitting the received physiological signal to an external receiving device (not shown) for the user to monitor the analyte. After the device is installed on the skin surface of the living being for a period of time, the emitter 3 can be separated from the base 1 and the sensor 2, and the base 1 and the sensor 2 can be replaced with new ones, so that the emitter 3 can be reused.
The base 1 includes a base body 11, and a patch 16 disposed on a bottom surface 116 (see fig. 6) of the base body 11. The patch 16 is used to attach to the skin of the living body.
The Sensor 2 includes a fixing seat 21 disposed on the base body 11, and a sensing member 22(Sensor) disposed on the fixing seat 21 and penetrating the base 1.
The fixing base 21 has a bottom surface 211 and a top surface 212. The sensing member 22 has a signal output end 221 protruding from the top surface 212 of the fixing base 21, and a signal detection end 222 connected to the signal output end 221 and protruding from the bottom surface 211 of the fixing base 21. The signal detection terminal 222 is used for being implanted under the skin of a living body to measure the analyte and transmit the sensed physiological signal to the signal output terminal 221.
Referring to fig. 2 and 11, the sensing element 22 includes a substrate 225, a plurality of electrodes 226 disposed on the surface of the substrate 225, and an analysis sensing layer (not shown) covering the electrodes 226 and the surface of the substrate 225, the analysis sensing layer is used for reacting with the analyte in the living body, the electrodes 226 are used for sensing the reaction result of the analysis sensing layer and transmitting the reaction result in the form of an electrical signal, in this embodiment, the electrical signal is the physiological signal and can reflect the concentration of glucose in blood.
Referring to fig. 2, 3 and 6, the emitter 3 includes a bottom shell 31 adjacent to the base body 11, a top shell 32 covering the bottom shell 31 and defining an inner space 30 together with the bottom shell 31, a circuit board 33 located in the inner space 30, a processing unit 34 (see fig. 10) located on the circuit board 33, a battery 35 located in the inner space 30 and electrically connected to the circuit board 33, and a port 36 connected to a bottom surface of the circuit board 33 and protruding out of the inner space 30 toward the base body 11.
The circuit board 33 can be a Printed Circuit Board (PCB) or a Flexible Printed circuit board (FPC) and is supported and fixed to the bottom case 31 by a supporting member 37, and the supporting member 37 can be made of a metal sheet. The circuit board 33 has a plurality of electrical contacts 331 corresponding to the ports 36, and in the present embodiment, the number of the electrical contacts 331 is eight.
The processing unit 34 is used for receiving, processing and outputting the physiological signal.
Referring to fig. 3, 6 and 7, the port 36 includes a housing 361 connected to the bottom surface of the circuit board 33 and protruding downward from the bottom surface 311 (see fig. 2) of the bottom shell 31 along the first axial direction D1, and a plurality of conductive members 364 disposed in the housing 361 and spaced apart from each other, in this embodiment, the number of the conductive members 364 is eight.
The housing 361 has a plurality of receiving slots 366 open toward the circuit board 33, and a receptacle 367 penetrating toward the base body 11 along the first axis D1 and communicating with the receiving slots 366. The conductive member 364 is rotatably received in the receiving groove 366. The insertion hole 367 is used for inserting the signal output end 221 of the sensing member 22.
Referring to fig. 4 and 5, in a variation of the first embodiment, the receiving slots 366 have a dovetail shape in a cross section perpendicular to the first axial direction D1, and each receiving slot 366 has a tapered shape from an end far away from the insertion hole 367 to an end adjacent to the insertion hole 367, so as to prevent each conductive member 364 from being separated from the receiving slot 366.
The conductive element 364 is an elastic member, and is located on both sides of the insertion hole 367, and abuts against the sensing element 22 and the circuit board 33 in two different axial directions, respectively. In this embodiment, the conductive elements 364 are coil springs, and respectively abut against the electrical contacts 331 of the circuit board 33 in the radial direction thereof along the first axial direction D1, and press against the electrodes 226 of the sensing element 22 in the radial direction thereof along the second axial direction D2, so as to clamp and accommodate the sensing element 22 in the insertion hole 367, and thereby provide electrical conduction. In detail, when the sensing element 22 is inserted into the insertion hole 367 along the insertion direction, since the conductive element 364, i.e. the coil spring, is movable in the receiving slot 366 and has a rotational degree of freedom, the conductive element 364 can rotate relatively in the receiving slot 366 (as shown by an arrow in fig. 6), so that the insertion and extraction resistance can be reduced by the movable design of the spring, which is convenient for a user to insert and extract the sensing element 22, and the repeated use can also be realized.
It should be noted that, in the present embodiment, each conductive element 364 is a coil spring, and one end of the coil spring is welded to the housing 361, so that each conductive element 364 is fixed in the respective receiving groove 366. In addition, the wire diameter of each conductive member 364 is less than 1mm, which is 0.1mm in this embodiment; the outer diameter is between 0.5mm and 1.8mm, in this example 1.1 mm; the free length is between 0.2mm and 0.8mm, in this embodiment 0.50 ± 0.06mm, and each conductor 364 has a coil portion 365a (see fig. 6), the number of turns of the coil portion 365a is between 2 and 6 turns, in this embodiment 3 turns, and each conductor 364 makes multi-point contact with the respective electrical contact 331 and the signal output terminal 221 via the coil portion 365 a. The wire diameter and the number of turns of each conductive element 364 are designed based on the elasticity of the conductive element 364, and the outer diameter and the free length are designed to make the conductive element 364 slightly larger than the accommodating space of the accommodating groove 366, so that the conductive element 364 can keep good contact with the electrical contact 331 and the electrode 226 (see fig. 2 and 10) by matching the parameter design of the wire diameter and the number of turns, thereby prolonging the service life of the product.
Referring to fig. 8, a variation of the first embodiment is that the conductive element 364 of the port 36 is changed into a rigid member, such as a steel ball or steel ring, and contacts the corresponding electrical contact 331 on the circuit board 33 and the electrode 226 of the sensing element 22 in a radial direction, and is also rotatably received in the receiving slot 366, so that the sensing element 22 can be inserted and pulled out smoothly. In addition, the port 36 further includes a plurality of elastic bodies 369 respectively received in the receiving groove 366, the elastic bodies 369 may be made of elastic materials such as rubber, and the elastic bodies 369 are located between the housing 361 and the conductive members 364, and each conductive member 364 abuts against the corresponding elastic body 369 and the corresponding electrode 226 of the sensing member 22 in the same axial direction (in the embodiment, the second axial direction D2) (see fig. 2 and 10). By using the rigid member as the conductive element 364 and matching with the pad of the elastic body 369, the reliability of electrically connecting the circuit board 33 and the sensing element 22 in different axial directions by the conductive element 364 can be improved.
Referring to fig. 9, in another variation of the first embodiment, each of the conductive members 364 is a spring and further has an extension 365b, the extension 365b extends along the inner surface of the casing 361 to between the casing 361 and the circuit board 33 and contacts the corresponding electrical contact 331 along the first axial direction D1.
Referring to fig. 10 and 11 synchronously, in the present embodiment, the processing unit 34 is configured to receive an electrical signal from the sensing element 22 and output a corresponding blood glucose value signal. The processing unit 34 includes a signal amplifier 341, a measurement and calculation module 342, and a communication module 343. The signal amplifier 341 is configured to receive and amplify the electrical signal. The measurement and calculation module 342 converts the amplified electrical signal into a corresponding digital signal and converts the digital signal into the blood glucose value signal. The communication module 343 is used for transmitting the blood glucose level signal to an external receiving device (not shown) via the antenna 344, and the electrical signal and the blood glucose level signal are collectively referred to as a physiological signal in the present invention.
In the present embodiment, the number of the conductors 364 is eight, and includes two power supply conductors 364a, four sensing signal conductors 364b, and two data transmission conductors 364 c. The electrodes 226 of the sensing element 22 are electrically connected to the electrical contacts 331 of the circuit board 33 through the conductive elements 364, respectively, so as to start various functions of power supply, sensing signal and data transmission.
The power supply conductors 364a are two and form a switch. The sensing signal conductors 364b are four and connect the processing unit 34. The data transmission conductors 364c are two and connected to the processing unit 34 and transmit data to an external receiving device through the communication module 343 and the antenna 344. In the present embodiment, the data transmission mode is described by taking wireless transmission (such as bluetooth, WIFI, NFC, etc.) as an example, but the present invention is not limited thereto, and in other embodiments, data transmission can be performed by a wired connection means (such as USB).
In detail, in the embodiment, there are five electrodes 226 of the sensing element 22, including a working electrode 226a, a reference electrode 226b, a power supply electrode 226e, and two electrical contact regions 226 d.
When the sensing element 22 is not inserted into the jack 367, the switch is in an open circuit state, so that the battery 35 is in a non-power-supplying state, and when the sensing element 22 is inserted into the jack 367, the power-supplying electrode 226e of the sensing element 22 is electrically conducted with the electrical contact 331 of the circuit board 33 through the power-supplying conductive element 364a, the working electrode 226a of the sensing element 22 is electrically conducted with the electrical contact 331 of the circuit board 33 through two of the sensing signal conductive elements 364b, and the reference electrode 226b is electrically conducted with the electrical contact 331 of the circuit board 33 through the other two sensing signal conductive elements 364 b. Therefore, the switch is switched to the closed state by the electrical conduction between the power supply electrode 226e and the electrical contact 331 of the circuit board 33, and the battery is switched to the power supply state, at this time, the battery 35 can provide the power required by the operations of the sensing element 22 and the processing unit 34 through the circuit board 33, so that the sensing element 22 performs the measurement of the analyte, and at the same time, the processing unit 34 can receive and process the physiological signal measured by the sensing element 22 and transmit the physiological signal to the external receiving device. And the electrical contact region 226d can electrically contact the data transmission conductor 364 c.
In addition to the aforementioned start mode, a variation mode as shown in fig. 12 can also be adopted, in which the sensing element 22 is directly started after being inserted without being controlled by the processing unit 34, and the difference between the variation mode and the first embodiment lies in the circuit design, which is a part that a person skilled in the art can design according to the needs, and therefore, the details are not described herein.
In addition, the jack 367 of the port 36 is also suitable for inserting an external transmission device (not shown) or a charging device (not shown), for example, when the transmitter 3 is assembled (in a state of not being connected to the sensor 2 and the base 1), a connector (or an electrode) of the external transmission device is inserted into the jack 367, and the external transmission device is electrically connected to the electrical contact 331 of the circuit board 33 through the data transmission conductor 364c, so that the external transmission device and the processing unit can transmit data to each other, and default data (e.g., calibration data) can be transmitted to the processing unit 34, that is, in this embodiment, the data transmission conductor 364c can be electrically connected to the external transmission device in advance for data transmission. In addition, after the transmitter 3 is removed and before the transmitter is reused, a connector of an external charging device can be inserted into the jack 367, and the external charging device is electrically connected to the electrical contact 331 of the circuit board 33 through the power supply conductive member 364a, so that the external charging device can charge the transmitter 3 to achieve the purpose of reusing the transmitter 3.
Referring to fig. 13, it is another variation of the sensing element 22 and the port 36 in the present embodiment, in the variation, the electrode 226 of the sensing element 22 includes a working electrode 226a, a counter electrode 226f, a power supply electrode 226e and two electrical contact regions 226d, and the number of the conductive elements 364 of the transmitter 3 is six, and the conductive elements 364 include two power supply conductive elements 364a, two sensing signal conductive elements 364b and two data transmission conductive elements 364 c. When the sensing element 22 is inserted into the receptacle 367 of the port 36, the working electrode 226a of the sensing element 22 is electrically connected to the electrical contact 331 of the circuit board 33 via the sensing signal conductor 364 b; the counter electrode 226f of the sensing element 22 is electrically connected to the electrical contact 331 of the circuit board 33 through the sensing signal conductor 364 b; the power supply electrode 226e of the sensing element 22 is electrically connected to the electrical contact 331 of the circuit board 33 through the power supply conductive element 364 a; the electrical contact region 226d of the sensing element 22 is electrically connected to the electrical contact 331 of the circuit board 33 through the data transmission conductor 364 c.
Referring to fig. 14, a variation of the sensing element 22 and the port 36 in the present embodiment is shown, in which the electrodes 226 of the sensing element 22 include a working electrode 226a, a counter electrode 226f and two power supply electrodes 226 e. The number of conductors 364 of the transmitter 3 is four, with conductors 364 comprising two power supply conductors 364a and two sensing signal conductors 364 b. When the sensing element 22 is inserted into the insertion hole 367 of the port 36, the working electrode 226a of the sensing element 22 is electrically connected to the electrical contact 331 of the circuit board 33 through the sensing signal conductor 364 b; the counter electrode 226f of the sensing element 22 is electrically connected to the electrical contact 331 of the circuit board 33 through the sensing signal conductor 364 b; the two power supply electrodes 226e of the sensing element 22 are electrically connected to the electrical contacts 331 of the circuit board 33 through the power supply conductors 364a, respectively.
With the configuration of the three sensing elements 22 and the port 36, the conductive element 364 electrically connects the electrodes 226 (working electrode 226a, reference electrode 226b, counter electrode 226f, and power supply electrode 226e) of the sensing element 22 with the electrical connection 331 of the circuit board 33, so that the signal amplifier 341 of the processing unit 34 receives and amplifies the electrical signal, the measurement and calculation module 342 converts the amplified electrical signal into a corresponding digital signal, and converts the digital signal into the blood glucose signal, and the communication module 343 transmits the blood glucose signal to an external receiving device via the antenna 344.
Before the present invention is used, the emitter 3 is separated from the sensor 2 and the base 1, and when a user wants to use the present invention, the base 1 is combined with the sensor 2 and is disposed on the living body, the emitter 3 is covered on the base 1, and the sensing member 22 is inserted into the insertion hole 367 of the port 36, so as to measure the analyte in the living body and transmit a corresponding physiological signal.
While the advantages of the first embodiment of the present invention are summarized as follows:
1. by abutting the conductive member 364 of the transmitter 3 against the sensing member 22 and the electrical contact 331 of the circuit board 33 along two different axial directions (D1/D2), the sensing member 22 can be connected to the transmitter 3 in an inserting manner, the sensing member 22 is stably clamped by the elastic conductive member 364, and stable connection and signal transmission between the sensing member 22 and the circuit board 33 are ensured.
2. In addition, the conductive component 364 is an elastic component, or a rigid component and cooperates with the cushion of the elastic component 369, so as to enhance the contact tightness between the conductive component and the sensing component 22 and the circuit board 33, thereby improving the reliability of the electrical connection, simplifying the overall configuration and facilitating the miniaturization. In this embodiment, the conductive element 364 is further configured to be allowed to rotate in the receiving groove 366, so that the insertion and extraction resistance is reduced by the movable design of the spring, which is convenient for a user to insert and extract the sensing element 22, thereby facilitating the repeated use.
3. In the present invention, when the transmitter 3 is not combined with the sensor 2, the power supply electrode of the sensing element 22 is not electrically connected to the electrical contact 331 of the circuit board 33 via the power supply conductive element 364a, so that the battery 35 is in an unpowered state, thereby avoiding unnecessary power consumption before use. In addition, the separated design of the transmitter 3 and the structure of the port 36 can also be inserted with an external charging device, the power supply electrode in the sensing element 22 is electrically conducted with the electrical contact 331 of the circuit board 33 through the power supply conductive element 364a, so that the external charging device can charge the processing unit. The data transmission conductive member 364c is electrically connected to the electrical contact 331 of the circuit board 33, so that data transmission can be performed between an external transmission device and the processing unit 34, and the port 36 can achieve a multifunctional purpose.
Referring to fig. 15 and 16, a second embodiment of the physiological signal sensing device of the present invention is similar to the first embodiment, except that:
the housing 361 of the port 36 of the transmitter 3 has a plurality of inclined surfaces 368 respectively located in the accommodating groove 366, each inclined surface 368 faces the circuit board 33 and the inserting hole 367 along the first axial direction D1 and the second axial direction D2, the inclined surfaces 368 are used for the conductive member 364 to rest, providing a pushing force of the conductive member 364 on the first axial direction D1 and the second axial direction D2, and pressing the conductive member 364 towards the circuit board 33 and the sensing member 22, so as to improve the moving flexibility of the conductive member 364, ensure the tight contact between the conductive member 364 and the circuit board 33 and the sensing member 22, and avoid the problem of poor subsequent derivative contact caused by the fact that the conductive member 364 cannot return after the sensing member 22 is pulled out.
In the second embodiment, the conductive element 364 is the same as the first embodiment, and adopts a coil spring, and contacts the corresponding electrical contact 331 on the circuit board 33 and the electrode 226 of the sensing element 22 in the radial direction thereof, and is rotatably accommodated in the accommodating groove 366, so that the sensing element 22 can be smoothly inserted and pulled out, but in other variation, the conductive element 364 may be changed into a rigid member, such as a steel ball or a steel ring, and also contacts the corresponding electrical contact 331 on the circuit board 33 and the electrode 226 of the sensing element 22 in the radial direction thereof (see fig. 2 and 10), and is disposed between the conductive element 364 and the inclined plane 368 in cooperation with a plurality of elastic body pads, so that the reliability of electrical connection can be improved, and the sensing element 22 can be smoothly inserted and pulled out.
Referring to fig. 17, a third embodiment of the physiological signal sensing device of the present invention is similar to the first embodiment except that:
in the first embodiment, the housing 361 of the port 36 and the bottom case 31 of the emitter 3 are integrally formed (as shown in fig. 6 and 8), while in the second embodiment, the port 36 and the bottom case 31 of the emitter 3 are separately manufactured objects, wherein the port 36 is in the form of an electrical connector and is disposed on the circuit board 33 by Surface-mount technology (SMT) and penetrates the bottom case 31 along the first axis D1. In addition, each of the conductive elements 364 of the port 36 is a resilient piece, and one end of the resilient piece contacts the corresponding electrical contact 331 on the circuit board 33 along the first axial direction D1, and the other end of the resilient piece abuts against the sensing element 22 along the second axial direction D2 to contact the electrode 226 of the sensing element 22, so that the conductive elements 364 of the resilient piece are used to electrically connect and hold the sensing element 22.
Referring to fig. 18, a fourth embodiment of the physiological signal sensing device of the present invention is similar to the first embodiment except that: the port 36 further includes a plurality of metal elastic pieces 370 respectively connected to the electrical contacts 331, and the metal elastic pieces 370 are welded to the electrical contacts 331, and bent toward the housing 361 and extended to the accommodating groove 366 to be located between the housing 361 and the conductive member 364. The conductive element 364 is an elastic member, specifically a coil spring, and radially abuts against the electrode 226 (see fig. 2 and 10) of the sensing element 22 and the corresponding metal elastic piece 370 in the same axial direction (in the present embodiment, the second axial direction D2). In this embodiment, the conductive element 364 is electrically connected to the electrical contact 331 by the metal spring 370, so as to improve the reliability of coaxial electrical connection.
Referring to fig. 19, in a variation of the fourth embodiment, the conductive element 364 can be a rigid member, specifically a steel ball, but can also be a rigid ring, and contacts the corresponding metal elastic piece 370 and the sensing element 22 in a radial direction. In addition, the metal dome 370 and the electrical contact 331 in the embodiment are connected by a Surface Mount Technology (SMT) process, but referring to fig. 20, in another variation of the fourth embodiment, the metal dome 370 and the electrical contact 331 can also be connected by a Dual in-line package (DIP) process.
It should be noted that, referring to fig. 21 and fig. 22, in the foregoing embodiments, the conductive element 364 in the port 36 may also be located on only one side of the insertion hole 367 for abutting one side of the sensing element, and the other side of the insertion hole 367 is abutted with the other side of the sensing element 22 in cooperation with the housing 361 or other members (not shown), so that the conductive element 364 can also achieve the function of clamping and electrically connecting the sensing element 22, for example, fig. 21 is a variation of the first embodiment, fig. 22 is a variation of the second embodiment, and other variations of the embodiments can be stacked as well.
In summary, according to the physiological signal sensing device of the present invention, the conductive member 364 of the transmitter 3 is located at least one side of the insertion hole 367, so that the conductive member 364 abuts against the sensing member 22 and the electrical contact 331 of the circuit board 33 after the transmitter 3 is combined with the sensor 2, and the sensing member 22 is clamped and electrically connected to the port 36, and the conductive member 364 is rotatably accommodated in the accommodating groove 366, so that the sensing member 22 can be effectively contacted with the conductive member 364, signals can be stably transmitted between the sensing member 22 and the circuit board 33, and the insertion and extraction resistance of the sensing member 22 can be reduced, so that the user can insert and extract the sensing member 22, which is more suitable for reuse. In addition, the conductive element 364 can be electrically conducted in different axial directions or in the same axial direction by using a spring, a steel ball or a steel ring, etc. in cooperation with the elastic body 369 or the metal elastic sheet 370, so as to meet design requirements of different purposes. Finally, the electrodes 226 of the sensing element 22 are electrically connected to the electrical contacts 331 of the circuit board 33 through the conductive elements 364, respectively, so as to start various functions of power supply, sensing signal and data transmission, thereby achieving the purpose of integrating multiple functions by using a single port 36.
The above description is only an example of the present invention, and the scope of the present invention should not be limited thereby, and the invention is still within the scope of the present invention by simple equivalent changes and modifications made according to the claims and the contents of the specification.
Claims (20)
1. A physiological signal sensing device for measuring a physiological parameter of an analyte in a living organism, comprising: comprises the following steps:
a sensing element having a signal output end and a signal detection end, wherein the signal detection end is implanted under the skin of the organism to measure a detection signal of the analyte of the organism, and the signal output end is used for outputting the detection signal; and
a transmitter coupled to the sensing element and configured to receive the detection signal and output a physiological parameter corresponding to the analyte after operation, the transmitter comprising:
a circuit board having a plurality of electrical contacts; and
the port is connected with the circuit board and is provided with a jack communicated with the circuit board and a plurality of steel balls accommodated in the port;
the sensing piece is inserted in the jack, one side of each steel ball is electrically connected with the respective electrical contact of the circuit board, and the signal output end of the sensing piece is electrically contacted with the other side of the steel ball, so that the signal output end of the sensing piece is electrically connected with the electrical contact of the circuit board by using the steel ball, and the steel ball can be movably contacted with the sensing piece along with the insertion and extraction of the sensing piece into and out of the jack.
2. The physiological signal sensing device of claim 1, wherein: the port further comprises a shell which is arranged on the bottom surface of the circuit board and is provided with the jack and a plurality of accommodating grooves communicated with the jack, and the accommodating grooves are used for accommodating the steel balls respectively.
3. The physiological signal sensing device of claim 2, wherein: the port further comprises a plurality of elastic bodies, and the elastic bodies are respectively arranged between the shell and the steel balls.
4. The physiological signal sensing device of claim 2, wherein: the steel ball of the port is positioned on one side of the jack.
5. The physiological signal sensing device of claim 2, wherein: the steel balls of the port are positioned on two opposite sides of the jack.
6. The physiological signal sensing device of claim 1, wherein: one side of each steel ball, which is contacted with the respective electric contact, and the other side of each steel ball, which is contacted with the signal output end, are positioned in two different axial directions.
7. The physiological signal sensing device of claim 1, wherein: the port is provided with a plurality of metal elastic sheets which are respectively connected with the electrical contacts and enable the steel balls to be pressed towards the direction of the sensing piece, one side of each steel ball is contacted with the respective metal elastic sheet so as to be electrically connected with the respective electrical contact, and the side of each steel ball contacted with each metal elastic sheet and the other side contacted with the signal output end are positioned on the same axial direction.
8. The physiological signal sensing device of claim 1, wherein: the sensing piece is inserted into the jack along a first axial direction, and the signal output end of the sensing piece is electrically contacted with each steel ball along a second axial direction.
9. The physiological signal sensing device of claim 1, wherein: the sensor also comprises a fixed seat, wherein the sensing piece is arranged on the fixed seat.
10. A physiological signal sensing device according to claim 9, wherein: the sensor further comprises a base which can be assembled on the emitter in a separated mode, wherein the fixing seat is contained between the emitter and the base, and the signal detection end of the sensing piece protrudes out of the bottom face of the fixing seat.
11. A physiological signal sensing device for measuring a physiological parameter of an analyte in a living organism, comprising: comprises the following steps:
a sensing element having a signal output end and a signal detection end, wherein the signal detection end is implanted under the skin of the organism to measure a detection signal of the analyte of the organism, and the signal output end is used for outputting the detection signal; and
a transmitter coupled to the sensing element and configured to receive the detection signal and output a physiological parameter corresponding to the analyte after operation, the transmitter comprising:
a circuit board having a plurality of electrical contacts; and
the port is connected with the circuit board and is provided with a jack communicated with the circuit board and a plurality of steel rings accommodated in the port;
the sensing piece is inserted into the jack, one side of each steel ring is electrically connected with the respective electrical contact of the circuit board, and the signal output end of the sensing piece is electrically contacted with the other side of the steel ring, so that the signal output end of the sensing piece is electrically connected with the electrical contact of the circuit board by the steel ring, and the steel ring can be movably contacted with the sensing piece along with the insertion and extraction of the sensing piece into and out of the jack.
12. A physiological signal sensing device according to claim 11, wherein: the port further comprises a shell which is arranged on the bottom surface of the circuit board and is provided with the jack and a plurality of accommodating grooves communicated with the jack, and the accommodating grooves are used for accommodating the steel ring respectively.
13. The physiological signal sensing device of claim 12, wherein: the port further comprises a plurality of elastic bodies, and the elastic bodies are respectively arranged between the shell and the steel ring.
14. The physiological signal sensing device of claim 12, wherein: the steel ring of the port is located on one side of the jack.
15. The physiological signal sensing device of claim 12, wherein: the port steel ring is positioned on two opposite sides of the jack.
16. A physiological signal sensing device according to claim 11, wherein: one side of each steel ring, which is contacted with the respective electrical contact, and the other side of each steel ring, which is contacted with the signal output end, are positioned in two different axial directions.
17. A physiological signal sensing device according to claim 11, wherein: the port is provided with a plurality of metal elastic sheets which are respectively connected with the electric contacts and enable the steel rings to be pressed towards the direction of the sensing piece, one side of each steel ring is contacted with the corresponding metal elastic sheet so as to be electrically connected with the corresponding electric contact, and the side of each steel ring contacted with each metal elastic sheet and the other side contacted with the signal output end are positioned on the same axial direction.
18. A physiological signal sensing device according to claim 11, wherein: the sensing piece is inserted into the insertion hole along a first axial direction, and the signal output end of the sensing piece is electrically contacted with each steel ring along a second axial direction.
19. A physiological signal sensing device according to claim 11, wherein: the sensor also comprises a fixed seat, wherein the sensing piece is arranged on the fixed seat.
20. The physiological signal sensing device of claim 19, wherein: the sensor further comprises a base which can be assembled on the emitter in a separated mode, wherein the fixing seat is contained between the emitter and the base, and the signal detection end of the sensing piece protrudes out of the bottom face of the fixing seat.
Applications Claiming Priority (6)
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| US201962882140P | 2019-08-02 | 2019-08-02 | |
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| TW109100852 | 2020-01-10 | ||
| TW109100852A TWI731545B (en) | 2019-08-02 | 2020-01-10 | Physiological signal sensing device |
| TW109100968A TWI735138B (en) | 2019-08-02 | 2020-01-10 | Physiological signal sensing device |
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| CN112294305A true CN112294305A (en) | 2021-02-02 |
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| CN202010314695.6A Pending CN112294305A (en) | 2019-08-02 | 2020-04-21 | Physiological signal sensing device |
| CN202010314803.XA Pending CN112294306A (en) | 2019-08-02 | 2020-04-21 | Physiological signal sensing device |
| CN202010315073.5A Pending CN112294307A (en) | 2019-08-02 | 2020-04-21 | Physiological signal sensing device |
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| CN202010315073.5A Pending CN112294307A (en) | 2019-08-02 | 2020-04-21 | Physiological signal sensing device |
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