CN112244012A - Hypochlorous acid gel and preparation method thereof - Google Patents
Hypochlorous acid gel and preparation method thereof Download PDFInfo
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- CN112244012A CN112244012A CN202011219392.2A CN202011219392A CN112244012A CN 112244012 A CN112244012 A CN 112244012A CN 202011219392 A CN202011219392 A CN 202011219392A CN 112244012 A CN112244012 A CN 112244012A
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- hypochlorous acid
- gel
- acid gel
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
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- General Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- Chemical & Material Sciences (AREA)
- Pest Control & Pesticides (AREA)
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- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
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Abstract
A hypochlorous acid gel and its preparation method are provided. The invention belongs to the field of gel products. The invention aims to solve the technical problems that the existing disinfection gel has certain irritation, is not suitable for people with sensitive skin, and is lack of a gel taking hypochlorous acid as a sterilization component. The hypochlorous acid gel is prepared from a hypochlorous acid solution, a regulator and a gel matrix, wherein the content of effective chlorine in the hypochlorous acid gel is 40-220 mg/L, and the pH value is 4.0-6.5. The preparation method comprises the following steps: and adding a regulator into the hypochlorous acid solution to regulate the pH value, heating to 10-50 ℃, adding the gel matrix, and uniformly stirring to obtain the hypochlorous acid gel. The hypochlorous acid gel disclosed by the invention has the advantages that the effective chlorine content is 40-220 mg/L, the pH value is 4.0-6.5, the sterilization, environmental protection and no stimulation are realized, and the gel is almost free of residues.
Description
Technical Field
The invention belongs to the field of gel products, and particularly relates to hypochlorous acid gel and a preparation method thereof.
Background
At present, common disinfection gel in the market basically takes one or two of ethanol and chlorhexidine acetate as disinfection components and has certain irritation. Ethanol, in particular, is volatile and unsuitable for children, and can cause skin irritation and even skin allergy for people with sensitive skin.
Hypochlorous acid is a disinfectant with strong oxidizing property, and has the characteristics of low dosage, quick sterilization, environmental protection, no stimulation and the like. Because the chemical property of hypochlorous acid solution is unstable and easy to be oxidized and decomposed, and hypochlorous acid can generate oxidation reaction with common gel matrix such as carbomer and the like, no report of preparing hypochlorous acid into gel exists at present, so that the research and development of hypochlorous acid gel with excellent sterilizing effect is particularly important for ensuring the stability and non-decomposition of hypochlorous acid and simultaneously ensuring the sterilizing performance of hypochlorous acid.
Disclosure of Invention
The invention provides hypochlorous acid gel and a preparation method thereof, and aims to solve the technical problems that the existing disinfection gel has certain irritation, is not suitable for people with sensitive skin, and is lack of gel taking hypochlorous acid as a sterilization component.
The hypochlorous acid gel is prepared from a hypochlorous acid solution, a regulator and a gel matrix, wherein the content of effective chlorine in the hypochlorous acid gel is 40-220 mg/L, and the pH value is 4.0-6.5.
Further limit, the regulator is one or a mixture of several of sodium bicarbonate, potassium carbonate, disodium hydrogen phosphate, sodium dihydrogen phosphate and sodium silicate according to any ratio.
Further limited, the gel matrix is lithium magnesium silicate, magnesium aluminum silicate or sodium carboxymethylcellulose.
The preparation method of the hypochlorous acid gel comprises the following steps:
and (3) adding a regulator into the hypochlorous acid solution to regulate the pH value, then adding the gel matrix at the temperature of 10-50 ℃, and uniformly stirring to obtain the hypochlorous acid gel.
Further limiting, the available chlorine content of the hypochlorous acid solution is 40 mg/L-220 mg/L, and the pH value is 4.0-6.5.
Further limiting, adding a regulator to adjust the pH value to 4.0-6.5.
Further limiting, adding a regulator to adjust the pH value to 5.0-6.5.
Further limiting, adding the gel matrix at the temperature of 20-40 ℃.
Further defined, the ratio of the volume of the hypochlorous acid solution to the mass of the gel matrix is 1L: (10-35) g.
Further, the rotation speed of the stirring is 500rpm to 2000 rpm.
Further limiting, stirring to a semi-solid state to obtain the hypochlorous acid gel.
Compared with the prior art, the invention has the following remarkable effects:
1) the invention uses hypochlorous acid to produce disinfection gel which can act on cell wall and virus shell, and has small molecule and no electric charge, and can permeate into the body of bacteria (virus) to generate oxidation reaction with protein, nucleic acid and enzyme of bacteria (virus) through cell wall, to destroy enzyme system of bacteria, to obstruct metabolism of bacteria, to kill pathogenic microorganism.
2) The hypochlorous acid gel disclosed by the invention has the advantages of 40-220 mg/L of available chlorine, 4.0-6.5 of pH value, sterilization, environmental protection, no stimulation and almost no residue.
3) When the disinfectant gel is prepared by using hypochlorous acid, the magnesium lithium silicate or the magnesium aluminum silicate is used as a gel matrix, so that the hypochlorous acid is stable and cannot be decomposed, and the sterilizing performance of the hypochlorous acid can be ensured.
4) The pH value of the finally formed gel is maintained between 5.0 and 6.5 by adjusting the pH value through the regulator, and the gel has excellent stability under the pH value.
5) The hypochlorous acid solution is heated, the gel matrix is added, the rapid dispersion and swelling of the gel matrix are increased, the heating temperature is not higher than 50 ℃, the hypochlorous acid decomposition is prevented, meanwhile, the gel matrix is not too fast and needs to be added continuously in a small amount, otherwise, the gel matrix is aggregated in the solution and cannot be dispersed.
6) The invention controls the stirring speed after adding the gel matrix so as to reduce the air entering in the stirring process.
7) The hypochlorous acid gel of the invention should be stored in a sealed and light-proof manner.
Detailed Description
The first embodiment is as follows: the preparation method of the hypochlorous acid gel of the embodiment comprises the following steps:
adding sodium bicarbonate into 1L hypochlorous acid solution to adjust pH to 6.5, heating to 50 deg.C, adding 35g magnesium lithium silicate, and stirring at 2000rpm to semisolid state to obtain hypochlorous acid gel; wherein the content of available chlorine in the hypochlorous acid solution is 220mg/L, and the pH value is 6.0.
The hypochlorous acid gel of the embodiment has an effective chlorine content of 217mg/L and a pH value of 6.5.
The second embodiment is as follows: the preparation method of the hypochlorous acid gel of the embodiment comprises the following steps:
adding potassium carbonate and sodium silicate into 1L hypochlorous acid solution to adjust the pH value to 5.5, heating to 20 ℃, adding 20g of magnesium aluminum silicate, and stirring at 500rpm to be in a semi-solid state to obtain hypochlorous acid gel; wherein the content of available chlorine in the hypochlorous acid solution is 40mg/L, and the pH value is 4.2.
The hypochlorous acid gel of this embodiment has an effective chlorine content of 41mg/L and a pH of 5.6.
The third concrete implementation mode: the preparation method of the hypochlorous acid gel of the embodiment comprises the following steps:
adding potassium carbonate and sodium silicate into 1L hypochlorous acid solution to adjust pH value to 6.2, heating to 30 deg.C, adding 25g sodium carboxymethylcellulose, and stirring at 1500rpm to obtain hypochlorous acid gel; wherein the content of available chlorine in the hypochlorous acid solution is 150mg/L, and the pH value is 6.2.
The hypochlorous acid gel of the embodiment has an effective chlorine content of 151mg/L and a pH value of 6.1.
Claims (9)
1. The hypochlorous acid gel is characterized by being prepared from a hypochlorous acid solution, a regulator and a gel matrix, wherein the content of effective chlorine in the hypochlorous acid gel is 40-220 mg/L, and the pH value is 4.0-6.5.
2. The hypochlorous acid gel of claim 1, wherein the regulator is one or more of sodium bicarbonate, potassium carbonate, disodium hydrogen phosphate, sodium dihydrogen phosphate, and sodium silicate.
3. The hypochlorous acid gel of claim 1, wherein said gel matrix is lithium magnesium silicate, magnesium aluminum silicate, or sodium carboxymethylcellulose.
4. The method for preparing hypochlorous acid gel according to any of claims 1 to 3, wherein the method comprises the following steps:
and (3) adding a regulator into the hypochlorous acid solution to regulate the pH value, then adding the gel matrix at the temperature of 10-50 ℃, and uniformly stirring to obtain the hypochlorous acid gel.
5. The method of claim 1, wherein the hypochlorous acid solution has an available chlorine content of 40mg/L to 220mg/L and a pH of 4.0 to 6.5.
6. The method of claim 1, wherein the pH of the hypochlorous acid gel is adjusted to 5.0 to 6.5 by adding a regulator.
7. The method for preparing hypochlorous acid gel according to claim 1, wherein the gel matrix is added at 20-40 ℃.
8. The method for preparing hypochlorous acid gel according to claim 1, wherein the ratio of the volume of hypochlorous acid solution to the mass of gel matrix is 1L: (10-35) g.
9. The method for preparing hypochlorous acid gel according to claim 1, wherein the stirring is performed at 500rpm to 2000rpm to obtain hypochlorous acid gel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011219392.2A CN112244012A (en) | 2020-11-04 | 2020-11-04 | Hypochlorous acid gel and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011219392.2A CN112244012A (en) | 2020-11-04 | 2020-11-04 | Hypochlorous acid gel and preparation method thereof |
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| CN112244012A true CN112244012A (en) | 2021-01-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202011219392.2A Pending CN112244012A (en) | 2020-11-04 | 2020-11-04 | Hypochlorous acid gel and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113069413A (en) * | 2021-03-31 | 2021-07-06 | 长沙海润生物技术有限公司 | Hypochlorous acid gel supporting electron beam irradiation sterilization and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140328945A1 (en) * | 2013-05-03 | 2014-11-06 | Aquaxo, Inc. | METHOD FOR STABILIZING AN ELECTROCHEMICALLY GENERATED SANITIZING SOLUTION HAVING A PREDETERMINED LEVEL OF FREE AVAILABLE CHLORINE AND pH |
| CN109418289A (en) * | 2017-09-05 | 2019-03-05 | 上海利康消毒高科技有限公司 | A kind of sodium hypochlorite gel and preparation method thereof |
-
2020
- 2020-11-04 CN CN202011219392.2A patent/CN112244012A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140328945A1 (en) * | 2013-05-03 | 2014-11-06 | Aquaxo, Inc. | METHOD FOR STABILIZING AN ELECTROCHEMICALLY GENERATED SANITIZING SOLUTION HAVING A PREDETERMINED LEVEL OF FREE AVAILABLE CHLORINE AND pH |
| CN109418289A (en) * | 2017-09-05 | 2019-03-05 | 上海利康消毒高科技有限公司 | A kind of sodium hypochlorite gel and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113069413A (en) * | 2021-03-31 | 2021-07-06 | 长沙海润生物技术有限公司 | Hypochlorous acid gel supporting electron beam irradiation sterilization and preparation method thereof |
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Application publication date: 20210122 |
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