CN112206407A - Electric field generating device, application thereof and method for anaesthetizing living body by applying electric field generating device - Google Patents
Electric field generating device, application thereof and method for anaesthetizing living body by applying electric field generating device Download PDFInfo
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- CN112206407A CN112206407A CN202010628498.1A CN202010628498A CN112206407A CN 112206407 A CN112206407 A CN 112206407A CN 202010628498 A CN202010628498 A CN 202010628498A CN 112206407 A CN112206407 A CN 112206407A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
Abstract
The invention provides an electric field generating device capable of anaesthetizing a living body, application thereof and a method for anaesthetizing the living body by applying the electric field generating device, wherein the electric field generating device comprises: two poles for forming an electric field, wherein the electric field is applied to a site to be anesthetized of a living body to achieve anesthesia.
Description
Technical Field
The invention relates to an electric field generating device capable of anesthetizing a living body, application thereof and a method for anesthetizing the living body by applying the electric field generating device.
Background
The original idea of anesthesia is to use drugs or other methods to make the body or part of the body of the person temporarily unconscious, so as to achieve the purpose of painlessness.
Medical ancestors have historically attempted to find a painless method of surgery. For example, the use of cryoanesthesia, vascular/nerve compression to achieve local sensory loss, coma and surgery in a patient may be problematic and lack safety concerns.
The ancient Egypt, India, Greece and other countries adopt cannabis, opium wine, stramonium and other analgesis once, can cause long-time sleep or coma with the help of the medicines, but is not easy to control the dosage and is easy to cause excessive poisoning; "Ma boil san" was invented by Hua Tuo, a great physician in China, and recorded in "Hua Tuo Lianzhong": "the disease is in the interior, the needle and the drug can not reach, the anaesthesia is unconscious when the ephedra is taken with wine first, and the accumulation is extracted and cut because the north abdomen is cut and broken; cutting off the intestine and stomach (28244), washing, removing the disease, then suturing, applying the magical ointment, healing for four or five days, and recovering within one month. This was the earliest record of the use of narcotics in the world's medical history, but none of these were anesthetics of modern significance.
The history of modern anesthesiology began in 1846 with great success from the first published demonstration of general anesthesia with ether by the morton physician in the united states at boston. 1846-1956 Ether dominates the anesthetic community for 110 years. Although three disadvantages of ether inhalation have been found: 1. easy to burn and explode, 2. toxic effects, 3. respiratory and circulatory inhibitory effects.
The isoflurane, the diflufenican, the sevoflurane and the like are sequentially published up to now, so that the anesthesia induction is accelerated, the revival is rapid, the safety is improved, and the anesthetic is a common inhalation anesthetic for clinical anesthesia. With the improvement of the anesthesia method and the detection technology and the cooperative application of various auxiliary medicines, the dosage and the concentration of the anesthetic can be accurately mastered, and the accuracy and the safety of anesthesia are greatly improved. After general anesthetic discovery, scientists have begun to search for local anesthetics that are not unconscious but have lost local sensation due to clinical needs. A physician in kohler in 1884; in 1892, the german physician schleich opened a local anesthetic by applying a subcutaneous injection of cocaine; in 1905, blaine found that the use of epinephrine enhanced the anesthetic effect and reduced toxicity of cocaine, and produced novocaine. Various chemical anesthetics and improvements in methods of anesthesia. Making the surgery increasingly sophisticated.
Any high level of surgery, anesthesia is not isolated. There was no pain and no pain in the party, and there was no call for any surgery. General anesthesia can be divided into local anesthesia and general anesthesia.
The general anesthetic is mainly inhaled or injected into a human body through a respiratory tract, and rapidly diffuses to the brain in a blood circulation mode, so that central nerve paralysis is caused, the consciousness of a patient is lost at the moment, and the general anesthetic effect is achieved. The main risk of this approach is to inhibit brain function, which may affect the respiratory system and circulatory system, causing hypoxia and, in severe cases, cardiac arrest. Local anesthesia is to apply local anesthetic to a certain part of a patient needing an operation, so that the conduction function of local nerves of the part is blocked, pain stimulation is not transmitted to the brain any more in the operation process, and the effect of inhibiting operation pain is achieved. This type of anesthesia works locally, but may also cause respiratory and cardiac arrest due to high toxicity.
As can be seen from the above, clinical anesthesia risks are mainly manifested in the suppression of the circulatory system and respiratory system. Death may be the result in more serious cases, but the incidence of this risk is extremely low. As long as the patient can accurately inform the doctor of other diseases combined by the patient and cannot tolerate general anesthesia or be unwilling to receive general anesthesia in the clinical actual treatment process, the medical staff can also take the patient opinion and situation as one of the standards for selecting the anesthesia mode to carry out local anesthesia as far as possible. For some patients, if the disease condition is relatively mild, only a short period of minor surgical treatment is needed, and in the case that the patient voluntarily carries out local anesthesia, a local anesthesia mode can also be adopted.
Disclosure of Invention
The invention provides an electric field generating device capable of anesthetizing a living body, application thereof and a method for anesthetizing the living body by applying the electric field generating device.
In order to achieve the purpose, the invention adopts the following technical scheme:
an object of the present invention is to provide an electric field generating apparatus for anesthetizing a living body, characterized by comprising: two poles for forming an electric field, wherein the electric field is applied to a site to be anesthetized of a living body to achieve anesthesia.
In one example of the electric field generating apparatus of the present invention: one of the two electrodes is a contact electrode which is contacted with a living body, the other electrode is an anesthesia electrode which covers the position of the living body to be anesthetized, and only the contact electrode is contacted with the living body.
In one example of the electric field generating apparatus of the present invention: wherein, the anesthesia electrode is a plurality of.
In one example of the electric field generating apparatus of the present invention: wherein the arrangement mode of the anesthesia electrodes is selected from lattice arrangement and is 2mLattice, where m is a non-0 natural number.
In one example of the electric field generating apparatus of the present invention: wherein, the bottom of each anesthesia electrode is coated with an insulating material or is composed of the insulating material, and is used for preventing the mutual interference between the adjacent anesthesia electrodes.
In one example of the electric field generating apparatus of the present invention: wherein the working voltage range of the electric field is 1-1000V, and the working distance range of the electric field is 0.1-100 cm.
In one example of the electric field generating apparatus of the present invention: wherein the working distance is any one of 0.1cm and 10 cm.
In one example of the electric field generating apparatus of the present invention: wherein, the electric field generating device also comprises a power supply.
In one example of the electric field generating apparatus of the present invention: the electric field generating device also comprises a regulating unit for regulating and controlling the electric field intensity of the electric field.
The invention also provides the application of the electric field generating device in making the substance to be permeated enter the target object, wherein the electric field generating device is the electric field generating device.
The invention also provides a method for anaesthetizing a living body, which adopts the electric field generated by the electric field generating device to anaesthetize the living body, wherein the electric field generating device is the electric field generating device.
In one example of the method of the present invention: the method comprises the following steps: step 1, contacting a contact electrode in an electric field generating device with a living body; and 2, covering the electric field generated by the contact electrode and the anesthesia electrode in the electric field generating device on the part to be anesthetized of the living body to realize anesthesia. In one example of the method of the present invention: wherein, the anesthesia electrode is a plurality of.
In one example of the method of the present invention: wherein the arrangement mode of the anesthesia electrodes is selected from lattice arrangement and is 2mLattice, where m is a non-0 natural number.
In one example of the method of the present invention: wherein, the bottom of each anesthesia electrode is coated with an insulating material or is composed of the insulating material, and is used for preventing the mutual interference between the adjacent anesthesia electrodes.
In one example of the method of the present invention: wherein the working voltage range of the electric field is 1-1000V, and the working distance range of the electric field is 0.1-100 cm.
In one example of the method of the present invention: wherein the working distance is any one of 0.1cm and 10 cm.
In one example of the method of the present invention: wherein, the electric field generating device also comprises a power supply.
In one example of the method of the present invention: the electric field generating device also comprises a regulating unit for regulating and controlling the electric field intensity of the electric field.
Experiments prove that the electric field can be used for anaesthetizing a living body, the electric field covers the part of the living body to be anaesthetized, the cuticle and the capillary vessel are broken through, the transmission of pain nerve signals of the target part (the part to be anaesthetized) is adjusted and shielded, and the non-invasive local anaesthesia function is realized. The low-strength electric field capable of selectively shielding pain nerves is generated by adjusting the output power (voltage and distance) of the electric field, so that the applicability is stronger, no dead angle exists in 360 degrees, the effect is better, and the safety performance is higher; the technology of carrying out anesthesia by using electric field penetration is an anesthesia mode which is convenient for the acceptance of the party and is especially suitable for local anesthesia, and compared with clinical modes of carrying out general anesthesia or local anesthesia on the anesthesia medicine and the like, the technology of carrying out anesthesia by using electric field penetration only intervenes or shields the signal feedback of pain nerve at the peripheral part of the illness of the party to the nerve center without adopting any medicine assistance, does not need to worry about adverse reactions caused by the tolerance and the drug toxicity performance of the anesthesia medicine, has the advantages of no pain in the using process, repeated implementation, no need of professional training and the like.
Further, the electric field device according to the present invention is provided with an electric field device in which one of the two electrodes is a contact electrode and the other is an anesthesia electrode to form an electric field, and since only the contact electrode is in contact with the living body, an equipotential is formed by the contact electrode being in contact with the living body, and the electric field device is easier to locate at an anesthesia site and is safer and more reliable than other types of electric fields (both electrodes generating the electric field are in contact with the living body or are not in contact with the living body).
Drawings
Fig. 1 is a structural diagram of an electric field generating apparatus according to embodiment 1;
fig. 2 is a schematic view of an arrangement of anesthetic electrodes of the electric field generating apparatus according to embodiment 1.
Detailed Description
The following specifically describes embodiments of the present invention.
The methods used in the following examples are conventional methods unless otherwise specified; the materials, reagents and the like used are commercially available unless otherwise specified.
Examples
The following examples are intended to specifically describe the electric field generating apparatus of the present invention, its use, and a method for anesthetizing a living body using the same.
Fig. 1 is a structural diagram of an electric field generating apparatus according to an embodiment.
The living body in fig. 1 shows only a part.
As shown in fig. 1, the electric field generating apparatus 100 according to the present embodiment is used for performing anesthesia on a living body, and particularly for performing anesthesia on a local area of the living body 1, and the electric field generating apparatus 100 includes: two poles 10 and 20 for forming an electric field, one of which serves as a cathode and the other as an anode, are used to generate an electric field that is applied to the site to be anesthetized to achieve anesthesia. In this embodiment, one of the two electrodes is a contact electrode 10 contacting with the living body, and the other electrode is an anesthesia electrode 20 covering the vicinity of the part to be anesthetized of the living body, wherein only the contact electrode 10 contacts with the living body to form an equipotential, while the anesthesia electrode 20 does not contact with the living body, and the position of the anesthesia electrode 20 is adjusted to allow an electric field to cover the part to be anesthetized of the living body to achieve anesthesia. In addition, one of the contact electrode 10 and the anesthetic electrode 20 is determined to be positive or negative according to the actual situation, and the other is determined to be negative or positive. In addition, the contact electrode 10 may also be grounded, which is safer than other forms of electric fields.
In the embodiment, the working voltage range of the electric field is 1-1000V, and the working distance range of the electric field is 0.1-100cm, so that the living body is not damaged by too large electric field strength and cannot realize the anesthesia purpose, and preferentially, the voltage of the electric field is one of 1V, 3V, 10V, 30V, 100V, 300V and 1000V; the working distance is any one of 0.1cm and 10 cm. The working distance here refers to the distance of the anesthesia electrode 20 from the site to be anesthetized.
In this embodiment, the anesthesia electrodes 20 are plural, so that the electric field can be conveniently positioned at the position to be anesthetized.
Fig. 2 is a schematic view of a first pole arrangement of the spatial electric field generating device according to the embodiment.
As shown in FIG. 2, the arrangement of the plurality of anesthetic electrodes 20 is selected from a lattice arrangement of 2mLattice, where m is a non-0 natural number, specifically 64 lattice, 4096 lattice, 16777216 lattice, etc., as shown in fig. 2. The degree of lattice density depends on the accuracy of the electric field. The precise action electric field is utilized to improve the action efficiency on the skin basal layer and reduce the influence on the normal tissue action. But is limited by the volume of the output electric field power supply, the lattice is dense and the power supply is large. Wherein any one or more of the longitude lines a \ b \ c till xx and any one or more of the latitude lines 1\2\3 till nn activate one or more of the dot matrix anesthetic electrodes 20, wherein activation means power-on. The active anesthesia electrode 20 and the contact electrode 10 form an action electric field, and the coverage area of the electric field is activeThe lattice poles are determined. This range may be from medical diagnostic image digital signals. Confirming the electric field range, the nerve cells can be accurately acted, and the influence on other tissues is reduced. Generally, 64 dot matrixes can only distinguish 64 electric field positions, 4096 dot matrixes can distinguish 4096 electric field positions, 16777216 dot matrixes can distinguish 16777216 electric field positions, the dot matrix effect is relatively accurate, and the influence on surrounding normal tissues is small. Can be adjusted according to the medical diagnosis image taken each time so as to correspond to the dot matrix of the medical diagnosis image, thereby being capable of quickly and accurately positioning the position to be acted (the part to be anesthetized). The positions of several anesthesia electrodes 20 positioned at the site to be anesthetized are illustrated in fig. 1, respectively: nx, c3, and a 1.
In this embodiment, the electric field generating apparatus 100 further includes: a power supply 30 and a regulation unit.
And the power supply 30 is used for supplying electric energy to the electric field generating device 100, the voltage is adjustable between 1V and 1000V, and the current output is adjustable between 0.001mA and 1 mA.
And the regulating and controlling unit is used for regulating and controlling the performance of the electric field, and the relevant parameters of the electric field performance mainly comprise one or more of the type, the direction, the electric field strength, the voltage, the current, the voltage waveform and the frequency of the electric field, and the frequency, the waveform and the amplitude of the power supply. Essentially, the performance of the electric field is determined by the site to be anesthetized and the field strength of the electric field.
The control unit can control and generate a first signal and a second signal, wherein the first signal is used for generating an electric field direction signal of local anesthesia and controlling the direction of a relatively generated electric field to be the direction of a part to be anesthetized; the second signal is used to enable electric field generation to facilitate electric field formation.
In addition, in one embodiment, the first signal controls the polarity of the electrodes relative to each other and the second signal modulates the anesthesia electrode 20 to generate an electric field strength of 1V/cm to 1000V/cm.
The electric field generation apparatus 100 according to the present embodiment can be applied to anesthesia of a living body.
In addition, the bottom of the anesthesia electrode 20 may be coated with or made of an insulating material for preventing mutual interference between adjacent anesthesia electrodes 20.
According to the above, the present embodiment also provides a method for anesthetizing a living body, comprising the steps of:
and 2, covering the electric field generated by the contact electrode 10 and the anesthesia electrode in the electric field generating device 100 on the part to be anesthetized of the living body to realize anesthesia.
Test examples
In this test, the criteria for the degree of anesthesia in the small animal test are as follows:
A. shallow anesthesia: the time from the start of electric field anesthesia or the time until the positive control injection of the drug naturally falls to the abdomen is 10 minutes or more. The animal breathes, the heart rate and the body temperature slightly decrease, the pain of the head, the neck, the trunk and the upper parts of the limbs of the animal is eliminated by acupuncture, and the eyelid reflex is sensitive.
B. Moderate anesthesia: the time from the beginning of electric field anesthesia or the time until the positive control injected drug naturally falls down to the abdomen is between 5 and 10 minutes. The animal respiratory frequency is 10-20 times/min, the heart rate is more than 50 times, the body temperature is reduced by 1-2 degrees, the pain of the head, neck, trunk and upper parts of limbs of the animal is removed by acupuncture, and the eyelid reflex is removed.
C. Deep anesthesia: the time from the start of electric field anesthesia or until the positive control injection drug naturally falls down to the abdomen is 4 minutes or less. The animal respiratory frequency is below 10 times/min, the heart rate is above 40 times, the body temperature is reduced to below 36 degrees, the pain of the head, neck, trunk and upper parts of limbs of the animal is pricked, the eyelid reflex disappears, the eyeball is inverted downwards, and only part of cornea is seen.
D. Overuse of anesthesia: the time from the start of electric field anesthesia or until the positive control injection drug naturally falls down to the abdomen is 4 minutes or less. The animal respiratory frequency is below 10 times/minute, the heart rate rhythm is irregular, the body temperature is reduced to below 36 degrees below 40 times, the pain sensation on the head, the neck, the trunk and the upper parts of the limbs of the animal is pricked, the eyelid reflex disappears, and the cornea reflex disappears.
1. Screening of laboratory animals
In the experiment, 4-6 weeks old Balbc mouse (weight 20g, healthy and glossy fur) is used as a candidate, and a local anesthesia contrast verification test is carried out after 1 week adaptation to the environment.
2. Establishment of animal model
(1) Positive control (group H)
Taking 0.1ml of 1% sodium pentobarbital/PBS (pH 6.8-7.0) solution, and taking a group of mice injected under the abdomen (n ═ 5) as a positive control; recording the time until the positive control group injects the medicine to naturally lie down to the abdomen, and judging the anesthesia effect through animal respiration, heart rate, body temperature, eyelid reflex sensitivity and the like
(2) Negative control (group I)
Taking a normal mouse (n-5) group as a negative control; and recording the respiration, heart rate, body temperature, eyelid reflex sensitivity and the like of the animals in the negative control group as a benchmark for judging the anesthesia effect.
(3) Electric field anesthesia experimental group
35 mice meeting the standard are randomly divided into different electric field local anesthesia groups (divided into A group (1V), B group (3V), C group (10V), D group (30V), E group (100V), F group (300V) and G group (1000V) according to the generated electric field voltage, and 5 mice are continuously stimulated for 10 minutes by adopting the electric field generating device provided by the embodiment, the time until the mice naturally lie on the back of the ground is recorded after the experiment is finished, and the anesthesia effect is judged through animal respiration, heart rate, body temperature, eyelid reflex sensitivity and the like.
3. Assessment of therapeutic efficacy
3-1: the working distance of the electric field is 10cm
After the working distance of the electric field is adjusted to 10cm, electric field local anesthesia experiments of 10 minutes are respectively carried out on the mice in the electric field anesthesia experiment group by adopting the electric fields generated by different working voltages. And (3) recording the time until the mice naturally lie down on the abdomen, and judging the anesthesia effect according to the standard of the anesthesia degree of the small animal test and the respiration, heart rate, body temperature, eyelid reflex sensitivity and the like of the animals, wherein the experimental effect is shown in the table 1.
According to Table 1, when the voltage of the anesthetic electric field is less than 10V, the anesthetic effect is hardly exhibited. When the electric field strength reaches 30-300V, the shallow anesthesia effect begins to appear. When the electric field intensity is continuously adjusted to 1000V, the anesthetic effect is continuously improved and almost consistent with that of 1% sodium pentobarbital/PBS. The phenomena of depth and overanesthesia do not occur.
3-2: the distance between the electrodes was set to 0.1cm
After the working distance of the electric field was adjusted to 0.1cm, electric field local anesthesia experiments were similarly performed for 10 minutes on the mice in the electric field anesthesia experimental group using electric fields generated by different working voltages, respectively. And (3) recording the time until the mice naturally lie down on the abdomen, and judging the anesthesia effect according to the standard of the anesthesia degree of the small animal test and the respiration, heart rate, body temperature, eyelid reflex sensitivity and the like of the animals, wherein the experimental effect is shown in the table 1.
According to Table 2, when the voltage of the electric field for anesthesia is lower than 30V, the shallow anesthesia occurs, and when the voltage is 30-100V, the moderate anesthesia is exhibited. When the electric field intensity reaches 300V, a severe anesthesia effect appears, and when the electric field intensity reaches 1000V, an overanesthesia phenomenon begins to appear.
It is proposed that in order to avoid the over-anesthesia, the voltage should be gradually increased by a preliminary experiment according to the tolerance of the subject to maintain the optimal anesthesia effect.
Local anesthetic is commonly used in small animal experiments to block peripheral nerve endings or nerve trunks, and a local anesthetic area is generated through signal conduction of ganglia and nerve plexuses, and the small animal experiment is characterized in that animals are kept awake, the interference on functions of important organs is slight, and the anesthetic complication is few. The clinical anesthesia effect monitoring and the judgment standard of the anesthesia depth are mostly used for comprehensively judging the anesthesia depth according to various reflex activities, body temperature, respiration, pulse and other vital signs in the animal anesthesia process. In clinic, shallow or moderate anesthesia is maintained as much as possible according to clinical needs. Deep anesthesia is avoided as much as possible, and overanesthesia is firmly avoided to prevent the occurrence of anesthesia accidents.
The foregoing embodiments are merely illustrative of the principles and utilities of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or change the above-mentioned embodiments without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.
In the above-described embodiment, only one of the two poles forming the electric field of the electric field generating device is in contact with the living body (contact electrode), and in practice, both the two poles forming the electric field may be in contact with the living body or not.
Claims (19)
1. An electric field generating apparatus for anesthetizing a living body, comprising:
the two poles for forming the electric field are,
wherein the electric field is applied to a site to be anesthetized of the living body to achieve the anesthesia.
2. The electric field generating apparatus according to claim 1, wherein:
wherein one electrode of the two electrodes is a contact electrode which is contacted with the living body, the other electrode of the two electrodes is an anesthesia electrode which covers the position of the living body to be anesthetized,
only the contact electrode is in contact with the living body.
3. The electric field generating apparatus according to claim 1 or 2, characterized in that:
wherein, the anesthesia electrode is plurally provided.
4. An electric field generating apparatus according to claim 3, wherein:
wherein the arrangement mode of the anesthesia electrodes is selected from lattice arrangement and is 2mLattice, where m is a non-0 natural number.
5. An electric field generating apparatus according to claim 3 or 4, wherein:
the bottom of each anesthesia electrode is coated with an insulating material or is made of the insulating material, and the insulating material is used for preventing the mutual interference between the adjacent anesthesia electrodes.
6. An electric field generating apparatus according to any one of claims 1 to 5, wherein:
wherein the working voltage of the electric field is 1-1000V,
the working distance range of the electric field is 0.1-100 cm.
7. The electric field generating apparatus according to claim 6, wherein:
wherein the working distance is any one of 0.1cm and 10 cm.
8. An electric field generating apparatus according to any one of claims 1 to 7, wherein:
wherein, the electric field generating device also comprises a power supply.
9. An electric field generating apparatus according to any one of claims 1 to 8, wherein:
the electric field generating device further comprises a regulating and controlling unit for regulating and controlling the electric field intensity of the electric field.
10. Use of an electric field generating device for anaesthetising a living subject, the electric field generating device comprising:
and anaesthetizing the living body by the electric field generated by the electric field generating device.
Wherein the electric field generating device is the electric field generating device according to any one of claims 1 to 9.
11. A method of anesthetizing a living subject, comprising:
the living body is anesthetized by the electric field generated by the electric field generating device.
Wherein the electric field generating device is the electric field generating device of claims 1-9.
12. The method of claim 11, comprising the steps of:
step 1, contacting a contact electrode in the electric field generating device with a living body;
and 2, covering the electric field generated by the contact electrode and the anesthesia electrode in the electric field generating device on the part of the living body to be anesthetized so as to realize the anesthesia.
13. The electric field generating apparatus according to claim 12, wherein:
wherein, the anesthesia electrode is plurally provided.
14. The method of claim 13, wherein:
wherein the arrangement mode of the anesthesia electrodes is selected from lattice arrangement and is 2mLattice, where m is a non-0 natural number.
15. The method according to claim 13 or 14, characterized in that:
the bottom of each anesthesia electrode is coated with an insulating material or is made of the insulating material, and the insulating material is used for preventing the mutual interference between the adjacent anesthesia electrodes.
16. The method according to any one of claims 11-15, wherein:
wherein the working voltage of the electric field is 1-1000V,
the working distance range of the electric field is 0.1-100 cm.
17. The method of claim 17, wherein:
wherein the working distance is any one of 0.1cm and 10 cm.
18. The method according to any one of claims 12-19, wherein:
wherein, the electric field generating device also comprises a power supply.
19. The method according to any one of claims 12-18, wherein:
the electric field generating device further comprises a regulating and controlling unit for regulating and controlling the electric field intensity of the electric field.
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| CN106267549A (en) * | 2016-08-24 | 2017-01-04 | 周玉梅 | A kind of novel intelligent controls without pain anesthesia armarium |
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| Publication number | Publication date |
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| WO2021004367A1 (en) | 2021-01-14 |
| CN218739871U (en) | 2023-03-28 |
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