CN112206386A - Air suction training instrument for lung inhalation administration - Google Patents
Air suction training instrument for lung inhalation administration Download PDFInfo
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- CN112206386A CN112206386A CN202011213643.6A CN202011213643A CN112206386A CN 112206386 A CN112206386 A CN 112206386A CN 202011213643 A CN202011213643 A CN 202011213643A CN 112206386 A CN112206386 A CN 112206386A
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- 238000012549 training Methods 0.000 title claims abstract description 41
- 210000004072 lung Anatomy 0.000 title description 9
- 230000002685 pulmonary effect Effects 0.000 claims abstract description 36
- 238000007405 data analysis Methods 0.000 claims abstract description 25
- 230000001133 acceleration Effects 0.000 claims abstract description 21
- 230000003434 inspiratory effect Effects 0.000 claims description 36
- 238000004364 calculation method Methods 0.000 claims description 10
- 238000004891 communication Methods 0.000 claims description 8
- 238000005259 measurement Methods 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 239000003814 drug Substances 0.000 abstract description 17
- 230000000694 effects Effects 0.000 abstract description 8
- 230000008021 deposition Effects 0.000 abstract description 5
- 238000012377 drug delivery Methods 0.000 abstract description 5
- 239000000443 aerosol Substances 0.000 description 17
- 230000001105 regulatory effect Effects 0.000 description 12
- 229940079593 drug Drugs 0.000 description 6
- 230000029058 respiratory gaseous exchange Effects 0.000 description 5
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 4
- 235000017491 Bambusa tulda Nutrition 0.000 description 4
- 241001330002 Bambuseae Species 0.000 description 4
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 4
- 239000011425 bamboo Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000003300 oropharynx Anatomy 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000012383 pulmonary drug delivery Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 206010057362 Underdose Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000003456 pulmonary alveoli Anatomy 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
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- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention belongs to the technical field of medical equipment and provides an inhalation training instrument for pulmonary inhalation drug delivery, which comprises a tank body, an inhalation cylinder, a resistance regulator, a flow sensor, a signal converter and a data analysis part. The air suction cylinder can rotate around the axis of the tank body; the fan-shaped adjusting holes on the resistance regulator coincide with different vent holes along with the rotation of the air suction cylinder, so that the resistance of the air flow is adjusted, the actual flow is measured by the flow sensor and is transmitted to the data analysis part after being converted by the signal converter, and the data analysis part calculates the air suction acceleration, the air suction peak flow speed and the air suction volume according to the flow data and displays the air suction acceleration, the air suction peak flow speed and the air suction volume through the display of the data analysis part. The inspiration training instrument for pulmonary administration enables data results such as inspiration acceleration, inspiration peak flow rate, inspiration volume and the like to be visualized, helps patients train inspiration modes, improves the pulmonary deposition rate of medicine and the uniformity of delivered dose, and enables the patients to obtain better treatment effect in the treatment of inhaled medicine.
Description
Technical Field
The invention belongs to the technical field of medical equipment, and particularly relates to an inhalation training instrument for pulmonary inhalation administration.
Background
The pulmonary inhalation drug delivery method is to disperse the drug into aerosol by using a special inhalation device, so that the aerosol is inhaled by a patient to play a local or systemic treatment role. The clinical administration effect is affected by the condition of the patient using the inhalation device, and the inhaled medicine can be classified into an aerosol, a pressurized metered dose aerosol (pMDI), a powder aerosol (DPI), a soft aerosol (SMI), etc. according to the type of the inhalation device. The principle of dispersing medicine into aerosol is different for each inhalation device, and patients also need to adopt different inhalation modes to cooperate with inhalation of aerosol in the using process. An aerosol, a pressure quantitative aerosol (pMDI) and a soft aerosol (SMI) belong to an inhalation device for actively spraying the aerosol, and a patient needs to match the flow rate of the aerosol in the inhalation process to keep slow and deep inhalation, so that the impact of the drug aerosol on the oropharynx part and the entrance of the drug aerosol into the lower respiratory tract and the alveolus along with the airflow are reduced, and the lung deposition rate is improved. The powder aerosol is generated by active inhalation of a patient to excite and disperse micronized medicine, and rapid and forceful inhalation is favorable for improving the output rate of the medicine and increasing the proportion of fine particles, thereby improving the deposition rate of the lung.
At present, the inspiration of the patient at home and abroad during the lung administration only depends on the oral guidance of medical workers to the patient, and the doctor can only guide the patient according to experience and abstract description because the doctor can not intuitively obtain reference data such as inspiration peak flow rate, inspiration acceleration, inspiration volume and the like in the guidance process. Therefore, when a patient uses an inhalation drug, the inhalation mode is lack of intuitive understanding, the individual feeling difference is large, the inhalation variation degree is large, the heterogeneity is high, and the conditions cause insufficient dosage or poor uniformity of the drug delivered to the lung, thereby affecting the treatment effect.
Disclosure of Invention
The present invention has been made to solve the above problems, and an object of the present invention is to provide an inhalation training apparatus for pulmonary inhalation administration.
The invention provides an inhalation training instrument for pulmonary inhalation administration, which is characterized by comprising: the tank body is columnar, two hollow ends of the tank body are open, a signal output port is formed in the side wall, the upper end of the tank body is connected with the air suction cylinder, an air inlet is formed in the lower end of the tank body, the air suction cylinder is a frustum body and is used for a user to suck air, the bottom of the air suction cylinder is connected with the upper end of the tank body and can rotate around the axis of the tank body, the resistance simulator comprises an air hole plate and a resistance adjusting plate which are in contact with each other, coaxially fixed and capable of rotating relatively, the air hole plate is circular and is arranged along the radial direction of the tank body, the edge of the air hole plate is fixed with the inner wall of the tank body, the air hole plate is provided with six air holes with different sizes, the resistance adjusting plate is circular and is arranged along the radial direction of the air suction cylinder, the edge of the resistance adjusting plate is fixed with the inner wall of, the resistance that the air current that the adjustment user produced when breathing in received, the air inlet, the air vent, fan-shaped regulation hole and the section of thick bamboo of breathing in form the air current route, flow sensor includes the tube-shaped body and signal acquisition spare, the tube-shaped body sets up at the internal, inside cavity both ends opening, the top is connected with the gas pocket board, the bottom is connected with jar body bottom, and the bottom diameter of the tube-shaped body equals with the air inlet diameter, signal acquisition spare is used for gathering pressure signal, set up on the tube-shaped body lateral wall, signal output part has, signal output part passes signal output mouth and is connected with the signal converter communication, signal converter accepts pressure signal, and convert pressure signal into flow signal, data analysis portion and signal converter communication are connected, be used for carrying out the analysis to the flow data of accepting, obtain the acceleration of.
The inhalation training instrument for pulmonary inhalation administration provided by the invention can also have the following characteristics: the air inlet is circular, the air inlet is divided into 12 equal parts by six separating strips, and the six separating strips extend to be in contact with the inner wall of the tank body along the radial direction of the air inlet and are crossed at the circle center of the air inlet.
The inhalation training apparatus for pulmonary inhalation drug delivery provided by the present invention may further include: the suction nozzle is detachably connected with the suction cylinder and used for allowing a user to inhale.
The inhalation training instrument for pulmonary inhalation administration provided by the invention can also have the following characteristics: wherein, the top of the air suction cylinder is inserted with the suction nozzle.
The inhalation training instrument for pulmonary inhalation administration provided by the invention can also have the following characteristics: wherein, the resistance adjusting plate is a circular plate with the diameter equal to that of the air hole plate.
The inhalation training instrument for pulmonary inhalation administration provided by the invention can also have the following characteristics: the air hole plate is provided with five circular vent holes and a fan-shaped vent hole which are uniformly distributed around the circle center of the air hole plate, the diameters of the five circular vent holes are sequentially increased, and the fan-shaped vent holes and the fan-shaped adjusting holes in the resistance adjusting plate can be completely overlapped.
The inhalation training instrument for pulmonary inhalation administration provided by the invention can also have the following characteristics: the outer wall of the air suction cylinder is provided with a rotating mark, the outer wall of the tank body is provided with a plurality of inhaler indicating marks, and when the air suction cylinder rotates, the rotating mark corresponds to different inhaler indicating marks, so that the resistance of the adjusted air flow is indicated.
The inhalation training instrument for pulmonary inhalation administration provided by the invention can also have the following characteristics: the signal converter is provided with a signal input port, a main control circuit board and a data output port, the signal input port is in communication connection with the signal output end of the flow sensor, the flow sensor inputs captured pressure signals into the main control circuit board through the data input port, and the main control circuit board converts the pressure signals into flow signals and inputs the flow signals into the data analysis portion through the data output port.
The inhalation training instrument for pulmonary inhalation administration provided by the invention can also have the following characteristics: the data analysis part draws an inspiration curve with time as an X axis and inspiration flow as a Y axis in real time according to the flow signal, calculates and displays inspiration acceleration, inspiration peak flow rate and inspiration volume, and the calculation method of the inspiration peak flow rate comprises the following steps: during inspiration, measuring gas flow every 0.1s, selecting maximum value, calculating inspiration peak flow rate, and calculating inspiration accelerationThe formula is as follows: inspiratory acceleration is inspiratory peak flow rate/time to peak, and the calculation formula of inspiratory volume is as follows: intake volume [ (intake flow rate (t) ]0) + inspiratory flow rate (t)1))×t]2+ [ (inspiratory flow rate (t))1) + inspiratory flow rate (t)2))×t]2+ … + [ (inspiratory flow rate (t)n-1) + inspiratory flow rate (t)n))×t]÷2。
The inhalation training instrument for pulmonary inhalation administration provided by the invention can also have the following characteristics: wherein the flow rate of the inspiration peak is in the range of 0L/min-300L/min, and the measurement range of the inspiration acceleration is 0L/s2-20 L/s2The measurement range of the suction volume is 0L-4L.
Action and Effect of the invention
The invention relates to an inhalation training instrument for pulmonary drug delivery, which comprises a tank body, an inhalation cylinder, a resistance regulator, a flow sensor, a signal converter and a data analysis part. The air suction cylinder can rotate around the axis of the tank body; the resistance regulator is provided with a resistance regulating plate, the resistance regulating plate is fixed on the air suction cylinder, the fan-shaped regulating holes on the resistance regulating plate coincide with different vent holes along with the rotation of the air suction cylinder, so that the resistance of airflow is regulated, an airflow passage is formed among the air inlet, the vent holes, the fan-shaped regulating holes and the air suction cylinder at the moment, and the airflow resistance is basically equivalent to the resistance of inhalation of a patient during inhalation administration. The flow sensor measures the actual flow of the patient during inspiration, the actual flow is transmitted to the data analysis part after being converted by the signal converter, and the data analysis part calculates the inspiration acceleration, the inspiration peak flow speed and the inspiration volume according to the flow data of the patient inspiration and displays the data on the display of the data analysis part.
Therefore, the inhalation training instrument for pulmonary administration provided by the invention provides a simple and accurate test instrument with visual results for measuring the inhalation acceleration, the inhalation peak flow rate and the inhalation volume of a user during inhalation, and a doctor can give accurate guidance to the patient according to real-time data to help the patient train the inhalation mode, thereby being beneficial to improving the deposition rate of the medicine in the lung of the patient and the uniformity of the medicine delivery dose, and further leading the patient to obtain better treatment effect in the treatment of inhaled medicine.
Drawings
FIG. 1 is a schematic diagram of an inhalation training apparatus for pulmonary inhalation delivery in accordance with an embodiment of the present invention;
FIG. 2 is a cross-sectional view of an inhalation bottle in an embodiment of the present invention;
FIG. 3 is a schematic view of the structure of an air intake in an embodiment of the invention;
FIG. 4 is a cross-sectional view of a resistance simulator in an embodiment of the invention;
FIG. 5 is a schematic structural view of a gas hole plate in an embodiment of the present invention;
FIG. 6 is a schematic view of a configuration of a resistance adjustment plate in an embodiment of the present invention;
fig. 7 is a schematic structural diagram of a signal converter in an embodiment of the present invention.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the efficacy of the invention easy to understand, the following describes a lung inhalation administration inhalation training instrument of the invention in detail with reference to the embodiment and the accompanying drawings.
< example >
The present embodiment describes the structure and the using method of the inhalation training apparatus 100 for pulmonary inhalation drug delivery.
Fig. 1 is a schematic structural view of an inhalation training apparatus for pulmonary inhalation drug delivery in this embodiment, and fig. 2 is a cross-sectional view of an inhalation bottle in this embodiment, the inhalation bottle being symmetrically cut.
As shown in fig. 1 and 2, an inhalation training apparatus 100 for pulmonary inhalation administration (hereinafter, referred to as inhalation training apparatus 100) includes an inhalation bottle 200, a signal converter 60, and a data analysis unit 70.
The inhalation bottle 200 comprises a can body 10, an inhalation cartridge 20, a mouthpiece 30, a resistance simulator 40, and a flow sensor 50.
The tank body 10 is a cylindrical tank body, the interior of the tank body is hollow, two ends of the tank body are opened, a signal output port 11 is formed in the side wall of the tank body, the top end of the tank body is connected with an air suction cylinder 20, and an air inlet 12 is formed in the bottom end of the tank body.
Fig. 3 is a schematic structural view of the intake port in the present embodiment.
As shown in fig. 3, the inlet 12 is circular, and the inlet 12 is divided into 12 equal parts by six dividing strips 121 uniformly distributed along the radial direction thereof and intersecting at the center thereof.
Six indication marks (not shown in the figures) and corresponding upward arrows (not shown in the figures) are printed on the upper portion of the outer wall of the can body 10, and the six indication marks are uniformly distributed around the circumference of the can body 10, and are respectively 'inhaler identifier a', 'inhaler identifier B', 'inhaler identifier C', 'inhaler identifier D', 'inhaler identifier E' and 'inhaler identifier F'. Each index mark corresponds to a different resistance that the inhalation training apparatus 100 can provide, which corresponds to the resistance to inhalation experienced by the patient receiving the administration of a pulmonary inhalation.
When a patient receives lung administration, because different inhalation devices have different principles for dispersing medicines into aerosol, the resistance suffered by the patient using different inhalation devices during inhalation is different, and the indication marks on the outer wall of the tank body 10 correspond to the resistance provided by the inhalation training instrument for simulating different inhalation devices respectively.
The air suction cylinder 20 is a frustum body, the interior of the air suction cylinder is hollow, two ends of the air suction cylinder are opened, the top end of the air suction cylinder is connected with the bottom end of the suction nozzle 30, the outer diameter of the bottom end of the air suction cylinder is matched with the inner diameter of the tank body 10, and the air suction cylinder is inserted into the top end of the tank body 10 and can rotate around the axis.
The outer wall of the air suction cylinder 20 is printed with a rotating mark 21, the rotating mark 21 is a downward-indicating arrow figure, and when the air suction cylinder 20 rotates, the rotating mark 21 rotates along with the rotating mark and points to corresponding upward arrows of different indicating marks to indicate resistance of air flow.
The suction nozzle 30 is used for the user to hold and inhale air, and is wholly cylindrical, and inside cavity both ends opening, bottom external diameter and the top internal diameter of a section of thick bamboo 20 of breathing in suit, thereby insert the top of a section of thick bamboo 20 of breathing in and can dismantle the connection together with the top of a section of thick bamboo 20 of breathing in.
Fig. 4 is a sectional view of the resistance simulator in the present embodiment, the resistance simulator is symmetrically cut, fig. 5 is a schematic structural view of an air hole plate in the present embodiment, and fig. 6 is a schematic structural view of a resistance adjustment plate in the present embodiment.
As shown in fig. 4-6, the resistance simulator 40 includes a resistance adjustment plate 42 and a central fixed shaft 43.
The center fixing shaft 43 vertically penetrates through the centers of the air hole plate 41 and the resistance adjusting plate 42 to coaxially fix the two plates together, and the air hole plate 41 and the resistance adjusting plate 42 are in contact with each other and can rotate relatively.
The gas hole plate 41 is a circular plate with a diameter of 35mm, is arranged on the upper part of the can body 10 along the radial direction of the can body 10, the axis of the gas hole plate coincides with the axis of the can body 10, and the edge of the gas hole plate is fixed with the inner wall of the can body 10 in a sticking mode. The air hole plate 41 includes five circular air holes 411 and one fan-shaped air hole 412 which are uniformly distributed around the center thereof.
The diameters of the five circular vent holes 411 are 3.5mm, 4.0mm, 4.5mm, 5.5mm and 6.0mm from small to large in sequence, the side length of the sector vent hole 412 is 10mm, and the central angle of the sector is 60 degrees. The diameter of the circle in which the edge arcs of the six vent holes are located is smaller than or equal to the diameter of the circle in which the fan-shaped vent holes 412 are located. In the scheme of the embodiment, the diameter of the circle in which the edge arcs of the six vent holes are located is smaller than that of the circle in which the fan-shaped vent hole 412 is located.
The resistance adjustment plate 42 is a circular plate having the same diameter as the air hole plate 41, is provided at the lower portion of the air suction cylinder 20 in the radial direction of the air suction cylinder 20, has an axis coinciding with the axis of the air suction cylinder 20, and has an edge fixed to the inner wall of the air suction cylinder 20 by means of adhesion. The resistance adjusting plate 42 is provided with a fan-shaped adjusting hole 421, the side length of the fan-shaped adjusting hole 421 is 10mm, and the central angle of the fan-shaped adjusting hole is 60 degrees.
Along with the rotation of the air suction cylinder 20, the resistance adjusting plate 42 synchronously rotates, so that the fan-shaped adjusting holes 421 are overlapped with different vent holes, and the resistance of the air flow is adjusted. During the rotation, the air hole plate 41 and the resistance adjustment plate 42 are relatively rotated around the central fixed shaft 43 at all times.
When a user inhales from the mouthpiece 30, the air inlet 12, the circular vent hole 411 or the fan-shaped vent hole 412, the fan-shaped adjustment hole 421 and the inhalation cylinder 20 can form an air flow path.
The flow sensor 50 is available from Zhengzhou Weisheng electronics technology Co., Ltd., model F1031V.
As shown in fig. 2, the flow sensor 50 includes a cylindrical body 51 and a signal acquisition member 52.
The cylindrical body 51 is fixed in the can body 10 in a sticking mode, the inner part is hollow, two ends of the cylindrical body are opened, the top end of the cylindrical body is connected with the air hole plate 41, the bottom end of the cylindrical body 51 is connected with the bottom end of the can body 10, and the diameter of the bottom of the cylindrical body 51 is equal to that of the air inlet 12.
The signal acquisition part 52 is fixed on the side wall of the cylindrical body 51 and is provided with a signal output end 521, and the signal output end 521 passes through the signal output port 11 to be in communication connection with the signal converter 60. The signal acquisition unit 52 measures the inspiratory flow rate according to the voltage variation, calculates the actual flow rate according to the following formula, and transmits the inspiratory flow rate and the actual flow rate to the signal converter 60 in the form of a pressure signal.
Actual flow calculation formula: the actual flow rate is full scale x (sensor output voltage-sensor zero output voltage)/(sensor full scale output voltage-sensor zero output voltage).
Fig. 7 is a schematic structural diagram of a signal converter in an embodiment of the present invention.
As shown in fig. 7, the signal converter 60 includes a rectangular parallelepiped case 61, a signal receiving terminal 62, a main control circuit board 63, a data output terminal 64, and a power supply 65.
The signal receiving terminal 62 is embedded in one side wall of the rectangular parallelepiped housing 61, and is connected to the signal output terminal 521 of the flow sensor 50 through a data line (not shown).
The main control circuit board 63 is disposed in the rectangular parallelepiped case 61, the signal receiving terminal 62 inputs the pressure signal into the main control circuit board 63, and the pressure signal is converted into a flow signal by the main control circuit board 63 and then input into the data analysis section 70 from the data output terminal 64.
The data output end 64 is embedded in the other side wall of the rectangular parallelepiped case 61 and is connected to the data analysis section 70 in communication via a data line.
The power supply 65 is disposed in the rectangular parallelepiped housing 61, and has a power supply inlet 651 electrically connected to an external power supply for supplying power to the main control circuit board 63.
The program of the data analysis section 70 draws an inhalation curve with time as the X-axis and inhalation flow as the Y-axis in real time from the flow signal, calculates inhalation acceleration, inhalation peak flow rate, and inhalation volume by calculation formulas, and displays them on the screen 71 of the data analysis section 70 in real time.
The calculation method of the inspiratory peak flow rate comprises the following steps: in the inspiration process, measuring the gas flow once every 0.1s, selecting the maximum value as the inspiration peak flow, and calculating the instantaneous inspiration peak flow rate by using the inspiration peak flow and the unit time 0.1s of the measured inspiration peak flow, wherein the range of the inspiration peak flow rate is 0L/min-300L/min, and the accuracy is 1L/min.
The calculation formula of the inspiration acceleration is as follows: inspiration acceleration is equal to inspiration peak flow rate/time to peak, accurate to 0.2L/s2。
The time to peak is the X-axis time corresponding to the inspiratory peak flow rate in the inspiratory curve.
The calculation formula of the suction volume is as follows: intake volume [ (intake flow rate (t) ]0) + inspiratory flow rate (t)1))×t]2+ [ (inspiratory flow rate (t))1) + inspiratory flow rate (t)2))×t]2+ … + [ (inspiratory flow rate (t)n-1) + inspiratory flow rate (t)n))×t]2, to an accuracy of 0.05L,
wherein, the inspiration flow rate is measured by the flow sensor, and is displayed on the screen 71 of the data analysis part 70 after being converted by the signal converter 60, and the unit is L/min;
inspiratory flow rate (t)0) The instantaneous inspiratory flow rate, measured for the start of inspiration, is typically 0L/min, the inspiratory flow rate (t)1) For the first measured instantaneous inspiratory flow rate, inspiratory flow rate (t)2) … inspiratory flow rate (t)n-1) Inspiratory flow rate (t)n) And so on;
t0the time corresponding to the inspiratory flow rate at the inspiratory initial time, t1For the time of the first measurement of inspiratory flow rate, t2…tn-1、tnAnd so on;
t is the time interval between two measurements of inspiratory flow rate.
The inhalation training instrument for pulmonary inhalation administration of the embodiment is used as follows:
when training begins, the doctor is instructed to start the inhalation training instrument 100 for pulmonary inhalation administration, the user rotates the inhalation cylinder 20 under the guidance of the doctor, the resistance adjustment plate 42 rotates synchronously until the rotation mark 21 on the inhalation cylinder 20 points to a certain indication mark on the tank body 10, at this time, a corresponding vent hole on the air hole plate 41 coincides with the fan-shaped adjustment hole 421, and the rest vent holes are shielded by the rest part of the resistance adjustment plate 42. When a user holds the suction nozzle 30 and inhales, the air flow in the cylindrical body 51 of the flow sensor 50 is drawn away along with the inhalation of the user, the air pressure in the cylindrical body 51 is less than the external atmospheric pressure, and the external air enters the cylindrical body 51 of the flow sensor 50 from the air inlet 12 to form the air flow. The flow sensor 50 measures the inspiration flow rate and the actual flow, converts the data through the main control circuit board 60 and transmits the data to the data analysis part 70, obtains three parameters of inspiration acceleration, inspiration peak flow rate and inspiration volume, and displays the three parameters on the screen 71, so as to provide reference for guiding the patient to adjust the inspiration mode by the doctor.
Effects and effects of the embodiments
The inhalation training instrument for pulmonary drug delivery according to the embodiment comprises a tank body, an inhalation cylinder, a resistance regulator, a flow sensor, a signal converter and a data analysis part. The air suction cylinder can rotate around the axis of the tank body; the resistance regulator comprises a resistance regulating plate, the resistance regulating plate is fixed on the air suction cylinder, the fan-shaped regulating holes in the resistance regulating plate coincide with different vent holes along with the rotation of the air suction cylinder, so that the resistance of airflow is regulated, an airflow passage is formed among the air inlet, the vent holes, the fan-shaped regulating holes and the air suction cylinder at the moment, and the airflow resistance is basically equivalent to the resistance of inhalation of a patient during inhalation administration. The flow sensor measures the actual flow of the patient during inspiration, the actual flow is converted by the signal converter and then transmitted to the data analysis part, and the data analysis part calculates inspiration acceleration, inspiration peak flow speed and inspiration volume according to the flow data of the patient inspiration.
In addition, the air inlet is divided into 12 identical grids by the separating strips, and air flow can be buffered and conformed when the user inhales, so that the situation that the oropharynx part is impacted by the air flow due to over-force is avoided when the user inhales.
In addition, the rotating mark on the air suction cylinder and the indicating mark on the tank body can intuitively indicate the gear of the current resistance on the air flow when a user rotates the air suction cylinder.
In addition, the areas of the vent holes on the air hole plate are sequentially increased from small to large, and the area of the used vent hole can be selected, so that the resistance of the sucked air flow is accurately controlled.
Therefore, the inhalation training instrument for pulmonary administration provided by the invention provides a simple and accurate testing instrument for measuring the inhalation acceleration, the inhalation peak flow rate and the inhalation volume of a user during inhalation, and the result is visualized, so that a doctor can give guidance to the patient according to real-time data to help the patient to train the inhalation mode, and the muscle memory formed after the patient is trained can effectively improve the heterogeneity of the inhalation curve among multiple inhalation administrations, and is beneficial to improving the pulmonary deposition rate of the medicine and the uniformity of delivered dose, so that the patient can obtain better and more stable treatment effect in the treatment of inhaled medicine, and the instrument has the advantages of small volume, easy use, low manufacturing cost and suitability for popularization and application.
The above embodiments are preferred examples of the present invention, and are not intended to limit the scope of the present invention.
Claims (10)
1. An inhalation training apparatus for pulmonary inhalation administration, comprising:
a tank body, an air suction cylinder, a resistance simulator, a flow sensor, a signal converter and a data analysis part,
wherein the tank body is columnar, the inner part of the tank body is hollow, two ends of the tank body are opened, the side wall of the tank body is provided with a signal output port, the upper end of the tank body is connected with the air suction cylinder, the lower end of the tank body is provided with an air inlet,
the air suction cylinder is a frustum body and is used for the user to suck air, the bottom of the air suction cylinder is connected with the upper end of the tank body and can rotate around the axis of the tank body,
the resistance simulator comprises an air hole plate and a resistance adjusting plate which are mutually contacted, coaxially fixed and can relatively rotate,
the air hole plate is round and arranged along the radial direction of the tank body, the edge of the air hole plate is fixed with the inner wall of the tank body, the air hole plate is provided with six air holes with different sizes,
the resistance adjusting plate is circular, is arranged along the radial direction of the air suction cylinder, is fixed together with the inner wall of the air suction cylinder at the edge, is provided with a fan-shaped adjusting hole, can cover different air holes along with the rotation of the air suction cylinder, adjusts the resistance of the air flow generated by the user during air suction,
the air inlet, the vent hole, the fan-shaped adjusting hole and the air suction cylinder form an air flow passage,
the flow sensor comprises a cylindrical body and a signal acquisition part,
the cylindrical body is arranged in the tank body, the hollow interior of the cylindrical body is provided with two open ends, the top of the cylindrical body is connected with the gas hole plate, the bottom of the cylindrical body is connected with the bottom end of the tank body, the diameter of the bottom of the cylindrical body is equal to that of the gas inlet,
the signal acquisition part is used for acquiring pressure signals, is arranged on the side wall of the cylindrical body and is provided with a signal output end which passes through the signal output port to be in communication connection with the signal converter,
the signal converter receives the pressure signal and converts the pressure signal into a flow signal,
the data analysis part is in communication connection with the signal converter and is used for analyzing the received flow data to obtain the inspiration acceleration, the inspiration peak flow speed and the inspiration volume.
2. The inhalation training apparatus for pulmonary inhalation delivery of claim 1, wherein:
wherein the air inlet is round,
the air inlet is divided into 12 equal parts by six dividing strips,
the six separating strips extend to the position, which is in contact with the inner wall of the tank body and crossed at the circle center of the air inlet, along the radial direction of the air inlet.
3. The inhalation training apparatus for pulmonary inhalation delivery of claim 1, further comprising:
a suction nozzle is arranged at the bottom of the suction pipe,
wherein, the suction nozzle is detachably connected with the air suction tube and is used for the user to inhale.
4. The inhalation training apparatus for pulmonary inhalation delivery of claim 3, wherein:
wherein, the top of the air suction cylinder is inserted with the suction nozzle.
5. The inhalation training apparatus for pulmonary inhalation delivery of claim 1, wherein:
wherein, the resistance adjustment plate is a circular plate with the same diameter as the air hole plate.
6. The inhalation training apparatus for pulmonary inhalation delivery of claim 5, wherein:
wherein, the gas hole plate is provided with five circular vent holes and a fan-shaped vent hole which are uniformly distributed around the circle center, the diameters of the five circular vent holes are increased in sequence,
the fan-shaped vent holes can be completely overlapped with the fan-shaped adjusting holes in the resistance adjusting plate.
7. The inhalation training apparatus for pulmonary inhalation delivery of claim 1, wherein:
wherein, the outer wall of the inhalation cylinder is provided with a rotary mark, the outer wall of the tank body is provided with a plurality of inhaler indicating marks,
when the inhalation cylinder rotates, the rotation mark corresponds to different inhaler indicator marks, thereby indicating the resistance to the airflow after adjustment.
8. The inhalation training apparatus for pulmonary inhalation delivery of claim 1, wherein:
wherein the signal converter is provided with a signal receiving end, a main control circuit board and a data output end,
the signal receiving end is in communication connection with the signal output end of the flow sensor,
the flow sensor inputs the captured pressure signal into the main control circuit board through the signal receiving end, and the main control circuit board converts the pressure signal into a flow signal and inputs the flow signal into the data analysis part through the data output end.
9. The inhalation training apparatus for pulmonary inhalation delivery of claim 1, wherein:
wherein the data analysis part draws an inspiration curve with time as an X axis and inspiration flow as a Y axis in real time according to the flow signal, calculates and displays the inspiration acceleration, the inspiration peak flow speed and the inspiration volume,
the calculation method of the inspiration peak flow rate comprises the following steps: measuring the gas flow every 0.1s in the inspiration process, selecting the maximum value, calculating the inspiration peak flow speed,
the calculation formula of the inspiration acceleration is as follows: inspiratory acceleration is the inspiratory peak flow rate/time to peak,
the calculation formula of the suction volume is as follows: intake volume [ (intake flow rate (t) ]0) + inspiratory flow rate (t)1))×t]2+ [ (inspiratory flow rate (t))1) + inspiratory flow rate (t)2))×t]2+ … + [ inspiratory flow rate (t)n-1) + inspiratory flow rate (t)n))×t]÷2。
10. The inhalation training apparatus for pulmonary inhalation delivery of claim 1, wherein:
wherein the measurement range of the flow velocity of the inspiration peak is 0L/min-300L/min,
the measurement range of the inspiration acceleration is 0L/s2-20L/s2，
The measurement range of the suction volume is 0L-4L.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011213643.6A CN112206386A (en) | 2020-11-04 | 2020-11-04 | Air suction training instrument for lung inhalation administration |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011213643.6A CN112206386A (en) | 2020-11-04 | 2020-11-04 | Air suction training instrument for lung inhalation administration |
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| CN112206386A true CN112206386A (en) | 2021-01-12 |
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| CN202011213643.6A Pending CN112206386A (en) | 2020-11-04 | 2020-11-04 | Air suction training instrument for lung inhalation administration |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114376514A (en) * | 2021-01-29 | 2022-04-22 | 浙江亿联康医疗科技有限公司 | Evaluation system and method for inhalation administration |
| WO2022161445A1 (en) * | 2021-01-29 | 2022-08-04 | 浙江亿联康医疗科技有限公司 | Method and system for evaluating inhalation administration |
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| US20040187869A1 (en) * | 2003-01-17 | 2004-09-30 | Schering Corporation | Training device for medicament inhalers |
| US20180256834A1 (en) * | 2015-09-16 | 2018-09-13 | Nicoventures Holdings Limited | Aerosol provision system with variable airflow |
| CN111419235A (en) * | 2020-04-21 | 2020-07-17 | 上海长海医院 | Inhalation peak flow meter for simulating inhaler resistance |
| CN213964699U (en) * | 2020-11-04 | 2021-08-17 | 张玮 | Air suction training instrument for lung inhalation administration |
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| US20040187869A1 (en) * | 2003-01-17 | 2004-09-30 | Schering Corporation | Training device for medicament inhalers |
| US20180256834A1 (en) * | 2015-09-16 | 2018-09-13 | Nicoventures Holdings Limited | Aerosol provision system with variable airflow |
| CN111419235A (en) * | 2020-04-21 | 2020-07-17 | 上海长海医院 | Inhalation peak flow meter for simulating inhaler resistance |
| CN213964699U (en) * | 2020-11-04 | 2021-08-17 | 张玮 | Air suction training instrument for lung inhalation administration |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114376514A (en) * | 2021-01-29 | 2022-04-22 | 浙江亿联康医疗科技有限公司 | Evaluation system and method for inhalation administration |
| WO2022161445A1 (en) * | 2021-01-29 | 2022-08-04 | 浙江亿联康医疗科技有限公司 | Method and system for evaluating inhalation administration |
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