CN112190979A - Emulsion breaking separator is used in bacterin processing - Google Patents

Emulsion breaking separator is used in bacterin processing Download PDF

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Publication number
CN112190979A
CN112190979A CN202010987304.7A CN202010987304A CN112190979A CN 112190979 A CN112190979 A CN 112190979A CN 202010987304 A CN202010987304 A CN 202010987304A CN 112190979 A CN112190979 A CN 112190979A
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wall
demulsification
rod
stirring
separation device
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CN202010987304.7A
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CN112190979B (en
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程联
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Zhongpu Biopharmaceutical Co ltd
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Individual
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D17/00Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02Separation of non-miscible liquids
    • B01D17/04Breaking emulsions
    • B01D17/047Breaking emulsions with separation aids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D17/00Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02Separation of non-miscible liquids
    • B01D17/04Breaking emulsions
    • B01D17/041Breaking emulsions with moving devices

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  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)

Abstract

The invention belongs to the technical field of vaccine culture, and particularly relates to a demulsification separation device for vaccine processing. According to the invention, the emulsion breaking needle is provided with the slide rail, the hydraulic rod, the slide sleeve, the first wave rod, the second stirring rod, the emulsion breaking needle, the stirring plate and the second emulsion breaking hole, the emulsion breaking needle is of a structure with different angles and different lengths, the second emulsion breaking hole is of a structure with different sizes, so that the emulsion breaking of vaccines at different positions can be realized, the emulsion breaking holes and the emulsion breaking needle can break emulsion oil particles in a vaccine solution, the stirring effect of the stirring mechanism can be improved in all directions, and the emulsion breaking efficiency is improved.

Description

Emulsion breaking separator is used in bacterin processing
Technical Field
The invention relates to the technical field of vaccine culture, in particular to a demulsification separation device for vaccine processing.
Background
The bacterin need break the emulsion in process of production, then carries out oil phase and water phase separation, reaches the effect of purifying vaccine, and prior art adopts and adds the demulsifier, carries out the breakdown of emulsion through the stirring, and the breakdown of emulsion is inefficient, reduces bacterin production speed, and the device that is used for the breaking of emulsion of bacterin and separation need be developed urgently to solve above-mentioned problem.
Through the retrieval, chinese patent is granted No. CN 210170889U's patent, discloses a device for bacterin breakdown of emulsion and separation, including backup pad, universal wheel, handle, discharge gate, jar body, refrigeration mechanism, temperature sensor, rabbling mechanism, feed inlet and automatically controlled cabinet, the utility model discloses set up broken breast hole on the stirring leaf, smash the emulsion oil grain in the bacterin is easy, improve rabbling mechanism's stirring effect.
The above patent also has the following disadvantages: only carry out the breakdown of emulsion through the breakdown of emulsion pore pair bacterin, can not be fine carry out the breakdown of emulsion to the bacterin to the rigidity of puddler among the above-mentioned device, the hole of breaking milk all sets up on the puddler, can not be comprehensive emulsify the bacterin, leads to the breakdown of emulsion inefficiency of device.
Disclosure of Invention
Based on the technical problem that the demulsification efficiency of the device is low because the vaccines are demulsified only through the demulsification holes provided in the background art and the vaccines cannot be well demulsified, and the stirring rods in the device are fixed in position and the demulsification holes are formed in the stirring rods and cannot be used for emulsifying the vaccines comprehensively.
The invention provides a demulsification and separation device for vaccine processing, which comprises a demulsification and separation box, wherein the outer wall of the top of the demulsification and separation box is provided with a motor, the output shaft of the motor is connected with a rotating rod through a coupler, the inner wall of the bottom of the demulsification and separation box is provided with a slide rail, the inner wall of the slide rail is connected with a hydraulic rod through a slide block in a sliding manner, the outer wall of the top of the hydraulic rod is provided with a cross rod, the two sides of the outer wall of the top of the cross rod are respectively provided with an arc rod, the outer wall of the rotating rod is connected with a sliding sleeve in a sliding manner, the top and the bottom of the outer wall of the sliding sleeve are respectively provided with a first wave rod and a second wave rod, the outer wall of the bottom of the second wave rod and the two sides of the outer wall of the top of the cross rod are respectively provided with arc rods, the, the outer wall of the bottom of the second stirring rod is provided with a stirring plate, and the outer wall of the stirring plate is provided with second breast breaking holes with different sizes.
Preferably, the outer wall of the bottom of the first wave rod is provided with a Y-shaped guide pipe, and the outer wall of the bottom of the Y-shaped guide pipe is provided with a stirring frame, and the stirring frame is of a rectangular structure.
Preferably, the inner wall of the stirring frame is provided with folding line rods distributed at equal intervals, and the folding line rods are of an inclined structure.
Preferably, the outer wall of the top of the cross rod is provided with first stirring rods distributed at equal intervals, and the outer wall of one side of each first stirring rod is provided with first breast breaking holes distributed at equal intervals.
Preferably, the outer wall of the top of the second wavy rod is provided with vertical rods with different heights, and the outer wall of one side of each vertical rod is movably connected with rotating blades distributed at equal intervals.
Preferably, the outer wall of the rotating vane is provided with second demulsifying needles which are distributed at equal intervals, and the outer wall of the rotating vane is provided with a sawtooth-shaped slot.
Preferably, the outer wall of the top of the demulsification separation box is provided with a feeding pipe, and the inner wall of the bottom of the demulsification separation box is provided with a discharging pipe.
Preferably, the top and the bottom of the two sides of the inner wall of the demulsification separation box are both provided with refrigerators, and the inner wall of one side of the demulsification separation box is provided with a temperature sensor.
Preferably, the outer wall of the top of the demulsification separation box is provided with a display screen, a signal input end of the display screen is connected with a processor through a signal line, and a signal output end of the temperature sensor is connected with a signal input end of the processor through a signal line.
Preferably, still including setting up in the manometer of emulsion breaking separator top outer wall, one side inner wall of emulsion breaking separator is provided with the pressure release pipe, and one side outer wall of pressure release pipe has the relief valve through threaded connection.
The beneficial effects of the invention are as follows:
1. this emulsification separator that emulsification is effectual, through being provided with the slide rail, the hydraulic stem, the slip cap, first wave pole, the second puddler, the breakdown of emulsion needle, the stirring board, the broken breast hole of second, connect hydraulic system with the hydraulic stem, open the motor, the motor drives the bull stick and rotates, and then the hydraulic stem can drive the second wave pole and rotate, and then second puddler and stirring board begin to rotate, can carry out abundant stirring to the bacterin, the breakdown of emulsion needle is the structure of the different just length of angle difference, the broken breast hole of second also is the different structure of variation in size specification, can carry out the breakdown of emulsion to the bacterin that is located different positions, broken breast hole of second and breakdown of emulsion needle can smash the emulsified oil grain in the bacterin solution, can omnidirectional improvement rabbling mechanism's stirring effect, improve breakdown of emulsion efficiency.
2. This emulsification separation device that emulsification is effectual, through being provided with the pole setting, the rotor, the second breakdown of emulsion needle, the zigzag fluting, Y shape pipe, stirring frame and broken line pole, the broken line pole is the structure that equidistant slope distributes, the mutual zigzag bar groove that forms of broken line pole also can carry out certain emulsification to the bacterin, the rotor both can mix the bacterin at the pivoted in-process, further breakage can be carried out to the emulsified oil grain in the bacterin solution through second breakdown of emulsion needle and saw-shaped tooth fluting again, further improvement the breakdown of emulsion efficiency of device.
3. This emulsification separation device that emulsification is effectual, through being provided with the refrigerator, temperature sensor, treater and display screen, when the temperature is higher, can open the refrigerator and cool down to the breakdown of emulsion separator box, both can carry out fine saving and can separate oil phase and the aqueous phase in the bacterin to the bacterin, in addition through being provided with the manometer, pressure release pipe and relief valve, the pressure value in the manometer detection device, when the pressure value surpassed the limit value, open the relief valve and carry out the pressure release, avoid the emergence of the unsafe condition.
The parts of the device not involved are the same as or can be implemented using prior art.
Drawings
FIG. 1 is a schematic structural diagram of a demulsification/separation apparatus for vaccine processing according to example 1 of the present invention;
FIG. 2 is a schematic view of part A of FIG. 1;
FIG. 3 is a schematic structural diagram of a slide rail of a demulsification/separation device for vaccine processing according to embodiment 1 of the present invention;
FIG. 4 is a schematic structural diagram of a demulsifying needle of a demulsifying and separating device for vaccine processing according to embodiment 1 of the present invention;
fig. 5 is a schematic structural diagram of a pressure gauge of the demulsification and separation device for vaccine processing according to embodiment 2 of the present invention.
In the figure: 1 emulsion breaking separator box, 2 refrigerators, 3 stirring boards, 4 stirring frames, 5 broken line poles, 6 emulsion breaking needles, 7 first wave poles, 8Y-shaped guide pipes, 9 feeding pipes, 10 sliding sleeves, 11 motors, 12 display screens, 13 rotating poles, 14 second wave poles, 15 first emulsion breaking holes, 16 first stirring poles, 17 cross bars, 18 temperature sensors, 19 sliding rails, 20 second emulsion breaking needles, 21 zigzag slots, 22 rotating vanes, 23 vertical poles, 24 hydraulic rods, 26 arc-shaped poles, 27 second stirring poles, 28 second emulsion breaking holes, 29 pressure gauges and 30 pressure relief pipes.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Example 1
Referring to fig. 1-4, a demulsification separating device for vaccine processing comprises a demulsification separating box 1, wherein a motor 11 is fixed on the outer wall of the top of the demulsification separating box 1 through screws, an output shaft of the motor 11 is connected with a rotating rod 13 through a coupler, a slide rail 19 is fixed on the inner wall of the bottom of the demulsification separating box 1 through screws, a hydraulic rod 24 is connected on the inner wall of the slide rail 19 through a slide block in a sliding manner, a cross rod 17 is fixed on the outer wall of the top of the hydraulic rod 24 through screws, arc-shaped rods 26 are welded on two sides of the outer wall of the top of the cross rod 17, a sliding sleeve 10 is connected on the outer wall of the rotating rod 13 in a sliding manner, a first wave rod 7 and a second wave rod 14 are respectively welded on the top and the bottom of the outer wall of the bottom of the second wave rod 14 and the outer wall of the top of the cross rod, and the outer wall of the second stirring rod 27 is welded with the demulsification needles 6 which are distributed equidistantly and have different sizes and different inclination angles, the outer wall of the bottom of the second stirring rod 27 is fixed with the stirring plate 3 through screws, and the outer wall of the stirring plate 3 is provided with second demulsification holes 28 which have different sizes and different specifications.
In the invention, the outer wall of the bottom of the first wavy rod 7 is fixed with a Y-shaped guide pipe 8 through a screw, the outer wall of the bottom of the Y-shaped guide pipe 8 is fixed with a stirring frame 4 through a screw, and the stirring frame 4 is of a rectangular structure.
According to the invention, the inner wall of the stirring frame 4 is fixed with the folding lines 5 which are distributed equidistantly through screws, the folding lines 5 are in an inclined structure, the outer wall of the top of the cross rod 17 is fixed with the first stirring rods 16 which are distributed equidistantly through screws, and the outer wall of one side of each first stirring rod 16 is provided with the first breast breaking holes 15 which are distributed equidistantly.
In the invention, the vertical rods 23 with different heights are welded on the outer wall of the top of the second wavy rod 14, the outer wall of one side of each vertical rod 23 is movably connected with rotating blades 22 which are distributed at equal intervals, the outer wall of each rotating blade 22 is provided with second demulsifying needles 20 which are distributed at equal intervals, and the outer wall of each rotating blade 22 is provided with a sawtooth-shaped slot 21.
In the invention, the outer wall of the top of the demulsification separation box 1 is connected with a feeding pipe 9 through a flange, the inner wall of the bottom of the demulsification separation box 1 is connected with a discharging pipe through a flange, the top and the bottom of two sides of the inner wall of the demulsification separation box 1 are both fixed with a refrigerator 2 through screws, and the inner wall of one side of the demulsification separation box 1 is fixed with a temperature sensor 18 through screws.
In the invention, a display screen 12 is fixed on the outer wall of the top of the demulsification separation box 1 through a screw, the signal input end of the display screen 12 is connected with a processor through a signal wire, and the signal output end of a temperature sensor 18 is connected with the signal input end of the processor through the signal wire.
The device is connected with a power supply, vaccine and demulsifier are added into the demulsification separating box 1 through a feeding pipe 9, a motor 11 is started, the motor 11 drives a rotating rod 13 to rotate, a fixed rod drives a hydraulic rod 24 to rotate inside a sliding rail 19, the hydraulic rod 24 is connected with a hydraulic system, the length of the hydraulic rod 24 is adjusted to enable a sliding sleeve 10 to slide up and down on the outer wall of the rotating rod 13, a first wave rod 7 and a second wave rod 14 rotate the rotating rod, a second demulsification hole 28 and a demulsification needle 6 can break emulsified oil particles in vaccine solution, the broken line rods 5 are in an equidistant inclined distribution structure, a saw-toothed strip-shaped groove formed by the broken line rods 5 can also carry out certain emulsification on the vaccine, a rotating vane 22 can mix the vaccine in the rotating process, and can further break the emulsified oil particles in the vaccine solution through the second demulsification needle 20 and the saw-toothed groove 21, when the temperature is higher, the refrigerator 2 can be opened to cool the demulsification separation box 1, so that the vaccine can be well stored, and the oil phase and the water phase in the vaccine can be separated.
Example 2
Referring to fig. 5, the demulsification separating device for vaccine processing in this embodiment further includes a pressure gauge 29 fixed to the outer wall of the top of the demulsification separating box 1 through a screw, the inner wall of one side of the demulsification separating box 1 is connected with a pressure relief pipe 30 through a flange, and the outer wall of one side of the pressure relief pipe 30 is connected with a pressure relief valve through a screw thread.
The device is connected with a power supply, vaccine and demulsifier are added into the demulsification separating box 1 through a feeding pipe 9, a motor 11 is started, the motor 11 drives a rotating rod 13 to rotate, a fixed rod drives a hydraulic rod 24 to rotate inside a sliding rail 19, the hydraulic rod 24 is connected with a hydraulic system, the length of the hydraulic rod 24 is adjusted to enable a sliding sleeve 10 to slide up and down on the outer wall of the rotating rod 13, a first wave rod 7 and a second wave rod 14 rotate the rotating rod, a second demulsification hole 28 and a demulsification needle 6 can break emulsified oil particles in vaccine solution, the broken line rods 5 are in an equidistant inclined distribution structure, a saw-toothed strip-shaped groove formed by the broken line rods 5 can also carry out certain emulsification on the vaccine, a rotating vane 22 can mix the vaccine in the rotating process, and can further break the emulsified oil particles in the vaccine solution through the second demulsification needle 20 and the saw-toothed groove 21, when the temperature is higher, can open refrigerator 2 and cool down to demulsification separator box 1, both can carry out fine saving to the bacterin and can separate the oil phase in the bacterin and aqueous phase, pressure value in the 29 detection device of manometer in addition, when the pressure value exceeded the limit value, opened the relief valve and carried out the pressure release, avoided the emergence of unsafe condition.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (10)

1. A demulsification separation device for vaccine processing comprises a demulsification separation box (1) and is characterized in that a motor (11) is arranged on the outer wall of the top of the demulsification separation box (1), an output shaft of the motor (11) is connected with a rotating rod (13) through a coupler, a sliding rail (19) is arranged on the inner wall of the bottom of the demulsification separation box (1), a hydraulic rod (24) is connected on the inner wall of the sliding rail (19) in a sliding mode through a sliding block, the outer walls of the hydraulic rod (24) and the rotating rod (13) are provided with the same fixed rod, a cross rod (17) is arranged on the outer wall of the top of the hydraulic rod (24), arc-shaped rods (26) are arranged on two sides of the outer wall of the cross rod (17), a sliding sleeve (10) is connected on the outer wall of the rotating rod (13) in a sliding mode, and a first wave rod (7) and a second, the bottom outer wall of second wave pole (14) and the top outer wall both sides of horizontal pole (17) all are provided with arc pole (26), the bottom outer wall both sides of first wave pole (7) all are provided with second puddler (27), and the outer wall of second puddler (27) is provided with the breakdown of emulsion needle (6) that the equidistance distributes and all differ in size specification and inclination, the bottom outer wall of second puddler (27) is provided with stirring board (3), and the outer wall of stirring board (3) is seted up the second that the size specification is different and is broken breast hole (28).
2. The demulsification and separation device for vaccine processing as claimed in claim 1, wherein the outer wall of the bottom of the first wavy rod (7) is provided with a Y-shaped conduit (8), the outer wall of the bottom of the Y-shaped conduit (8) is provided with the stirring frame (4), and the stirring frame (4) is of a rectangular structure.
3. The demulsification and separation device for vaccine processing as claimed in claim 2, wherein the inner wall of the stirring frame (4) is provided with folding lines (5) which are distributed equidistantly, and the folding lines (5) are of an inclined structure.
4. The demulsification and separation device for vaccine processing as claimed in claim 1, wherein the top outer wall of the cross bar (17) is provided with first stirring rods (16) which are distributed equidistantly, and one side outer wall of each first stirring rod (16) is provided with a first demulsification hole (15).
5. The demulsification and separation device for vaccine processing as claimed in claim 4, wherein the top outer wall of the second wavy rod (14) is provided with vertical rods (23) with different heights, and the outer wall of one side of each vertical rod (23) is movably connected with rotating blades (22) which are distributed at equal intervals.
6. The demulsification and separation device for vaccine processing as claimed in claim 5, wherein the outer wall of the rotary vane (22) is provided with second demulsification needles (20) which are distributed equidistantly, and the outer wall of the rotary vane (22) is provided with zigzag-shaped slots (21).
7. The demulsification and separation device for vaccine processing as claimed in claim 6, wherein the top outer wall of the demulsification and separation box (1) is provided with a feeding pipe (9), and the bottom inner wall of the demulsification and separation box (1) is provided with a discharging pipe.
8. The demulsification and separation device for vaccine processing as claimed in claim 1, wherein the demulsification and separation box (1) is provided with a refrigerator (2) at the top and the bottom of the two sides of the inner wall, and the demulsification and separation box (1) is provided with a temperature sensor (18) at the inner wall of one side.
9. The demulsification and separation device for vaccine processing as claimed in claim 8, wherein a display screen (12) is arranged on the outer wall of the top of the demulsification and separation box (1), the signal input end of the display screen (12) is connected with the processor through a signal line, and the signal output end of the temperature sensor (18) is connected with the signal input end of the processor through a signal line.
10. The demulsification and separation device for vaccine processing as claimed in claim 1, further comprising a pressure gauge (29) arranged on the outer wall of the top of the demulsification and separation box (1), wherein a pressure relief pipe (30) is arranged on the inner wall of one side of the demulsification and separation box (1), and a pressure relief valve is arranged on the outer wall of one side of the pressure relief pipe (30).
CN202010987304.7A 2020-09-18 2020-09-18 Emulsion breaking separator is used in bacterin processing Active CN112190979B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113244664A (en) * 2021-05-12 2021-08-13 伍俊雄 Device for demulsifying and separating vaccine
CN114712897A (en) * 2022-03-25 2022-07-08 江苏中慧元通生物科技股份有限公司 Demulsification separation system for processing tetravalent influenza virus subunit vaccine

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EP0734750A1 (en) * 1995-03-31 1996-10-02 Nikolaus Hammerschmitt Light liquid separator
RU2149680C1 (en) * 1999-03-24 2000-05-27 Чиргин Сергей Георгиевич Device for dissolving, emulsification and dispersing of various materials
CN205288194U (en) * 2016-01-19 2016-06-08 苏州市兴邦化学建材有限公司 Water -reducing agent agitating unit
CN208426912U (en) * 2018-05-08 2019-01-25 浙江科峰新材料有限公司 A kind of multifunctional emulsified tank
CN109589826A (en) * 2018-11-23 2019-04-09 李天天 A kind of emulsion pot used for cosmetic collected convenient for miscellaneous material
CN209362208U (en) * 2018-12-19 2019-09-10 个旧金冶再生科技有限责任公司 It is a kind of to prepare refined tin desulphurization system
CN209393087U (en) * 2018-12-18 2019-09-17 天津国民健康技术有限公司 A kind of agitating device of vacuum emulsification agitator tank
CN110681279A (en) * 2019-11-08 2020-01-14 四川轻化工大学 Yak milk cheese apparatus for producing
CN210170889U (en) * 2019-05-13 2020-03-24 杭州佑本动物疫苗有限公司 Device for demulsifying and separating vaccine
CN210544682U (en) * 2019-09-11 2020-05-19 江西省华宝孔雀食品科技发展有限公司 Emulsification device is used in production of grape oil microemulsion essence
CN210875074U (en) * 2019-10-31 2020-06-30 黑龙江昊天玉米开发有限公司 High fructose syrup is auxiliary material preparation equipment for production line

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Publication number Priority date Publication date Assignee Title
EP0734750A1 (en) * 1995-03-31 1996-10-02 Nikolaus Hammerschmitt Light liquid separator
RU2149680C1 (en) * 1999-03-24 2000-05-27 Чиргин Сергей Георгиевич Device for dissolving, emulsification and dispersing of various materials
CN205288194U (en) * 2016-01-19 2016-06-08 苏州市兴邦化学建材有限公司 Water -reducing agent agitating unit
CN208426912U (en) * 2018-05-08 2019-01-25 浙江科峰新材料有限公司 A kind of multifunctional emulsified tank
CN109589826A (en) * 2018-11-23 2019-04-09 李天天 A kind of emulsion pot used for cosmetic collected convenient for miscellaneous material
CN209393087U (en) * 2018-12-18 2019-09-17 天津国民健康技术有限公司 A kind of agitating device of vacuum emulsification agitator tank
CN209362208U (en) * 2018-12-19 2019-09-10 个旧金冶再生科技有限责任公司 It is a kind of to prepare refined tin desulphurization system
CN210170889U (en) * 2019-05-13 2020-03-24 杭州佑本动物疫苗有限公司 Device for demulsifying and separating vaccine
CN210544682U (en) * 2019-09-11 2020-05-19 江西省华宝孔雀食品科技发展有限公司 Emulsification device is used in production of grape oil microemulsion essence
CN210875074U (en) * 2019-10-31 2020-06-30 黑龙江昊天玉米开发有限公司 High fructose syrup is auxiliary material preparation equipment for production line
CN110681279A (en) * 2019-11-08 2020-01-14 四川轻化工大学 Yak milk cheese apparatus for producing

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113244664A (en) * 2021-05-12 2021-08-13 伍俊雄 Device for demulsifying and separating vaccine
CN114712897A (en) * 2022-03-25 2022-07-08 江苏中慧元通生物科技股份有限公司 Demulsification separation system for processing tetravalent influenza virus subunit vaccine

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