CN1121819A

CN1121819A - Oral medicine for treating necrosis of femoral head

Info

Publication number: CN1121819A
Application number: CN 94114861
Authority: CN
Inventors: 黄克勤
Original assignee: Individual
Current assignee: Individual
Priority date: 1994-08-13
Filing date: 1994-08-13
Publication date: 1996-05-08
Anticipated expiration: 2014-08-13
Also published as: CN1049133C

Abstract

The oral medicine for treating femur head necrosis is prepared from 26 Chinese-medicinal materials such as ground beetle, Chinese angelica root, lindera root, honeylocust thorn, spatholobus stem, etc.

Description

A kind of oral medicine for the treatment of osteonecrosis of femoral head

The present invention relates to a kind of oral medicine for the treatment of osteonecrosis of femoral head, belong to the Chinese medicine formulation art.

Hip joint is one of human body six big joints, is that human repeating motion is maximum, and the maximum joint of femoral head carrying in case necrose, will become a great problem in the medical domain, be called " new cancer ".General traditional medical science viewpoint thinks that bone necrosis, particularly femur head necrosis can not repair, and is irreversible.Therefore replace artificial joint, substitute the main treatment means that has just become this disease with prosthese.Artificial femoral head replacement's infectious-related complication is difficult to overcome, and occur to infect, loosening, joint stiffness, pain etc., can cause patient's lifelong disability.Research to the femur head necrosis paathogenic factor, be commonly considered as the necrosis that blood supply disorder causes in the femoral head, under this theoretical direction, treatment means is a purpose to improve the blood supply environment, has occurred Therapeutic Method such as vascular transplant, muscle flap vessel pedicle transplantation, bone lobe dislocation art, fetus cartilage dislocation art, interventional therapy in succession.Tcm therapy is based on blood circulation promoting and blood stasis dispelling, bone and muscle strengthening, nourishing the liver and kidney, and external treatment adopts the plaster external application.Above-mentioned therapy is to reparation, the treatment of necrotic femoral head, and the throughput fractional analysis does not still have final conclusion at aspects such as pathology, histologys.

Rationale is breakthrough to be discovered, the femur head necrosis paathogenic factor is not ischemic femoral head and blood supply disorder, but ultrastructure changes in the femoral head, internal stress of bone changes, the piezoelectric property of bone and electrokinetic property disorder, the electrical environment disequilibrium produces potential difference.This electrical environment destroys reason medicine source property, mechanicalness and chemical reason.Therapeutic Method then to improve the bio electricity environment, restores balance it.According to this theory, the inventor invents and has developed Huang Shi therapeutic apparatus for femoral head necrosis (China Patent No. CN92111451.6), is applied to the patient and has obtained excellent curative, and in order to improve curative effect, the inventor has developed the serial Chinese medicine that cooperates this instrument to use.

The object of the invention then provides the oral medicine that a kind of Huang Shi of cooperation femoral head therapeutic instrument uses.

Medicine of the present invention is that the Chinese medicine with following proportioning (weight ratio) is the oral medicine that raw material is made:

Eupolyphaga Seu Steleophaga 18-22g Radix Angelicae Sinensis 18-22g Radix Linderae 18-22g

Fructus Gleditsia 8-12g Caulis Spatholobi 12-18g Pericarpium Citri Reticulatae Viride 12-18g

Cornu Cervi Degelatinatum 28-35g Pheretima 18-22g Radix Glycyrrhizae 8-12g

Rhizoma Corydalis 18-22g Herba Lycopodii 18-22g Galla Chinensis 18-22g

Cattle sunset 18-22g Hirudo, 18-22g Radix Astragali 28-32g

Cornu Bubali 28-32g Radix Salviae Miltiorrhizae 18-22g Fructus Lycii 18-22g

Semen Persicae 18-22g Herba Cistanches 18-22g Rhizoma Cyperi 18-22g

Herba speranskiae tuberculatae 28-32g halberd sky 28-32g membrana follicularis ovi, 100-110g

Squama Manis 18-22g Carapax et Plastrum Testudinis 18-22g

Oral medicine of the present invention can be prepared into any oral medicine according to a conventional method, comprises pill, tablet, electuary, oral liquid etc.

The preparation method of bolus of drug of the present invention is:

With the oven dry of above-mentioned raw materials medical material, be ground into fine powder, making pellets by mixing medical powder with honey, every ball 18 grams.

Medicine of the present invention and Huang Shi therapeutic apparatus for femoral head necrosis are used, and can be used for treating femur head necrosis, subside, and the joint space narrows down, dysfunction, and diseases such as the hip arthralgia have the necrotic bone of reparation structure, activate the necrotic bone cell, the effect of accelerated bone growth.

Medicine of the present invention in use uses through clinical 1027 examples, and 1782 hip joint treatments are analyzed, and total effective rate reaches 97.2%, and cure rate reaches 54.2%.Wherein:

1, improve hip joint function, take care of oneself, the hip joint activity is normal substantially, outer bend, interior receipts, bend hip, after stretch and reach positive physiological function scope person 842 examples, account for sum 41.5%.

2, collapse of the femoral head, acetabular bone are destroyed, the joint stiffness patient removes sequestrum by treatment, the area of new bone structure occurs, and joint space improver 212 examples account for sum 11.9%.

3, pain relief, normal, the femoral head carrying improvement of terms of walking can be adhered to worker's 362 examples, accounts for sum 19.8%.

4, femur head necrosis is the sclerosis ischemic necrosis, the loose type patient of femoral head hypertrophy dwindles by the treatment femoral head, and improve the joint space, area of new bone girder person 126 examples occur, accounts for sum 7.3%.

5, femur head necrosis is molten bone destruction, a head distortion subluxation or a complete dislocation occur, also receives and resets through treating remaining femoral head, and sequestrum is removed, and newborn carrying bone trabecula improves the carrying environment, can the person's of taking care of oneself 137 examples, account for 7.9%.

6, femur head necrosis has been replaced artificial joint, pain and is liied in bed unbearably and can not walk, and through the treatment pain relief, can hold and turn walker 18 examples, accounts for sum 1.05%.

7, femur head necrosis underwent operative treatment, joint capsule destroyed hip joint structure biomechanics occurs and change, and nonresponder's 49 examples account for sum 2.8%.

Embodiment:

Composition of raw materials is as follows

Eupolyphaga Seu Steleophaga 20g Radix Angelicae Sinensis 20g Radix Linderae 20g Fructus Gleditsia 10g Caulis Spatholobi 15g

Pericarpium Citri Reticulatae Viride 15g Cornu Cervi Degelatinatum 30g Pheretima 20g Radix Glycyrrhizae 10g Rhizoma Corydalis 20g

Herba Lycopodii 20g Galla Chinensis 20g cattle sunset 20g Hirudo (processing) 20g Radix Astragali 30g

Cornu Bubali 30g Radix Salviae Miltiorrhizae 20g Fructus Lycii 20g Semen Persicae 20g Herba Cistanches 20g

Rhizoma Cyperi 20g Herba speranskiae tuberculatae 30g halberd sky 30g membrana follicularis ovi 100g Squama Manis 20g

Carapax et Plastrum Testudinis 20g

With above-mentioned medical material oven dry, be ground into fine powder, making pellets by mixing medical powder with honey, every ball weight is 18g.

Claims

1, a kind of medicine for the treatment of femur head necrosis is characterized in that it is the oral medicine made from following proportion raw material: