CN112175805A - Biological cell separation device convenient to get and put test tube - Google Patents

Biological cell separation device convenient to get and put test tube Download PDF

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Publication number
CN112175805A
CN112175805A CN202011022082.1A CN202011022082A CN112175805A CN 112175805 A CN112175805 A CN 112175805A CN 202011022082 A CN202011022082 A CN 202011022082A CN 112175805 A CN112175805 A CN 112175805A
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China
Prior art keywords
test tube
fixed block
rotating disc
rack
gear
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CN202011022082.1A
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Chinese (zh)
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韦文杰
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Individual
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/08Flask, bottle or test tube
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/46Means for fastening
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/48Holding appliances; Racks; Supports

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Centrifugal Separators (AREA)

Abstract

The invention relates to the technical field of biological cells, and discloses a biological cell separation device convenient for taking and placing test tubes, which comprises a toothed ring, a rotating disc and six driven wheels, wherein threaded rods are inserted into the six driven wheels, clamping blocks are fixedly connected to the tops of the six threaded rods, a driving wheel is rotated on the inner rear wall of the toothed ring, six test tube grooves are formed in the top of the rotating disc, the bottoms of the six test tube grooves are movably connected with fixing blocks, gears and clamps are rotatably connected to one sides of the six test tube grooves far away from the center of the rotating disc and one sides of the six test tube grooves near the center of the rotating disc, and racks are arranged on one sides of the gears far away from the fixing blocks. Through action wheel, ring gear, drive the fixed block lapse from driving wheel and threaded rod cooperation, it is fixed with the test tube to drive anchor clamps through gear, rack, chute and slider when the fixed block lapse to reached and prevented that the test tube from colliding with the test-tube groove when the centrifugation, caused the effect of harm to the test tube.

Description

Biological cell separation device convenient to get and put test tube
Technical Field
The invention relates to the technical field of biological cells, in particular to a biological cell separation device convenient for taking and placing test tubes.
Background
Biological cells generally refer to stem cells, most biologists and medical scientists currently consider that stem cells come from embryos, fetuses or in vivo cells with the capacity of unlimited self-renewal and proliferation differentiation under certain conditions, and the stem cells have extremely wide application prospects in the fields of cell repair, developmental biology, pharmacology and the like of life sciences.
Biological cells are often separated in biological research, so that people can conveniently observe cells in a diversified manner, a test tube is only placed in a test tube groove when a general biological cell separation device is used for centrifugation, no further protection device is provided, the test tube is easily damaged when being collided in the test tube groove, and after separation is finished, an operator generally takes out the test tube with hands to observe, so that the operation is troublesome, bacteria on the hands easily pollute a separated sample, and therefore the biological cell separation device convenient for taking and placing the test tube is provided.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides the biological cell separation device convenient for taking and placing the test tube, which has the advantages of fixing and protecting the test tube, preventing the test tube from being damaged during centrifugation and being convenient for taking and placing the test tube for observation, and solves the problems that the test tube is easily damaged when being collided in a test tube groove, and after the separation is finished, an operator needs to take out the test tube by hands to observe the test tube, and bacteria on the hands are easy to pollute a separated sample.
(II) technical scheme
In order to realize the purposes of fixing and protecting the test tube, preventing the test tube from being damaged during centrifugation and facilitating the test tube taking and placing for observation, the invention provides the following technical scheme: a biological cell separation device convenient for taking and placing test tubes comprises a box body, wherein a motor and six fixed cylinders are fixedly connected to the inner bottom wall of the box body, the tops of the six fixed cylinders are rotatably connected with driven wheels, threaded rods are inserted into the six driven wheels, a toothed ring is rotatably connected to the interior of the box body, clamping blocks are fixedly connected to the tops of the six threaded rods, a driving wheel is rotated on the inner rear wall of the toothed ring, a rotating disc is rotatably connected to the top of the motor, six test tube grooves are formed in the top of the rotating disc, fixed blocks are movably connected to the bottoms of the six test tube grooves, gears and clamps are rotatably connected to one sides of the six test tube grooves, which are far away from the center of the rotating disc, and one sides of the gears, which are close to the center of the rotating disc, racks are arranged on one sides of the gears, which are far away from, six equal fixedly connected with two dead levers of interior diapire of test-tube slot.
Preferably, the gear ring is meshed with the driving wheel and the six driven wheels, and the driving wheel drives the six driven wheels to rotate through the gear ring.
Preferably, one side of the fixed block, which is far away from the center of the rotating disc, and one side of the fixed block, which is close to the center of the rotating disc, are both provided with teeth and are meshed with the gear.
Preferably, the rack is meshed with the gear, and the fixed block drives the rack to move up and down through the gear when moving up and down.
Preferably, the rack penetrates through the fixture, inclined grooves are formed in the inner walls of the two sides of the fixture, which are in contact with the rack, two sliding blocks are arranged outside the rack, and the sliding blocks are located in the inclined grooves, so that the rack drives the fixture to move left and right through the sliding blocks and the inclined grooves when moving up and down in the fixture.
Preferably, the effect that the direction that drives the kelly and toward being close to the fixed block removed is played to the equal fixedly connected with reset spring in one side that the kelly carried on the back mutually, and the bottom of kelly all is provided with the spout, and the dead lever passes through the spout and drives the kelly and toward the direction of keeping away from nearly fixed block and remove.
Preferably, the opposite sides of the clamp are provided with spongy cushions, so that the test tube is protected.
(III) advantageous effects
Compared with the prior art, the invention provides a biological cell separation device convenient for taking and placing test tubes, which has the following beneficial effects:
1. this biological cell separator convenient to get and put test tube, on putting the fixed block of test tube inslot into through testing the test tube, the action wheel passes through the ring gear and drives from the driving wheel rotation, from driving wheel and passing through the threaded rod drive fixed block lapse, after tooth and gear contact on the fixed block, drive rack lapse through the gear, the rack passes through chute and slider and drives anchor clamps and slide to the direction that is close to the test tube, and then fixed the test tube, thereby reached and prevented that the test tube from colliding with the test tube groove when the centrifugation, cause the effect of harm to the test tube.
2. This biological cell separator convenient to get and put test tube, the action wheel passes through the ring gear and drives from the driving wheel rotation, it drives the fixture block upwards to slide to pass through the threaded rod from the driving wheel, after the fixture block contacts with the fixed block, can drive the fixed block upwards and slide, the fixed block passes through gear and rack and drives anchor clamps and slide toward the direction of keeping away from the test tube, separate with the test tube, the threaded rod continues to the ejecting test tube groove of fixed block, thereby reach the effect of being convenient for observe the progress of cell separation in the test tube, avoided artificially contacting the test tube and caused bacterial contamination, and the threaded rod drives the test tube at the uniform velocity slow rising at fixed block top, the form of cell separation in having avoided the test tube.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the structure A of FIG. 1 according to the present invention;
FIG. 3 is a schematic view of the structure B of FIG. 1 according to the present invention;
FIG. 4 is a schematic top view of the clamp configuration of the present invention;
FIG. 5 is a schematic top view of a ring gear structure according to the present invention.
In the figure: 1. a box body; 2. a fixed cylinder; 3. a motor; 4. a driven wheel; 5. a threaded rod; 6. a toothed ring; 7. a clamping block; 8. a driving wheel; 9. rotating the disc; 10. a test tube groove; 11. a fixed block; 12. a gear; 13. a rack; 14. a clamp; 15. a clamping rod; 16. and (5) fixing the rod.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, a biological cell separation device convenient for taking and placing test tubes comprises a box body 1, a motor 3 and six fixed cylinders 2 are fixedly connected to the inner bottom wall of the box body 1, driven wheels 4 are rotatably connected to the tops of the six fixed cylinders 2, threaded rods 5 are inserted into the six driven wheels 4, a toothed ring 6 is rotatably connected to the inside of the box body 1, clamping blocks 7 are fixedly connected to the tops of the six threaded rods 5, a driving wheel 8 is rotatably connected to the inner rear wall of the toothed ring 6, the toothed ring 6 is meshed with the driving wheel 8 and the six driven wheels 4, the driving wheel 8 drives the six driven wheels 4 to rotate through the toothed ring 6, a rotating disc 9 is rotatably connected to the top of the motor 3, six test tube slots 10 are formed in the top of the rotating disc 9, fixed blocks 11 are movably connected to the bottoms of the six test tube slots 10, a gear 12 and a clamp 14 are rotatably connected to one side of the six test tube slots 10 away from, teeth are arranged on one side of the fixed block 11, which is far away from the center of the rotating disc 9, and one side of the fixed block 11, which is close to the center of the rotating disc 9, and are meshed with the gear 12, a rack 13 is arranged on one side of the gear 12, which is far away from the fixed block 11, the rack 13 is meshed with the gear 12, the rack 13 is driven by the gear 12 to move up and down when the fixed block 11 moves up and down, the rack 13 penetrates through the clamp 14, a sponge pad is arranged on one opposite side of the clamp 14 to protect the test tube, inclined grooves are formed in the inner walls of two sides, which are in contact with the rack 13, of the clamp 14, two sliding blocks are arranged outside the rack 13, the sliding blocks are positioned in the inclined grooves, the clamp 14 is driven by the sliding blocks and the inclined grooves to move left and right when the rack 13 moves up and down in the clamp 14, two, play the effect that drives kelly 15 and remove toward the direction of being close to fixed block 11, and the bottom of kelly 15 all is provided with the spout, drives kelly 15 through the spout and removes toward the direction of keeping away from nearly fixed block 11 when dead lever 16 contacts with kelly 15.
The working principle is as follows: when biological cells are separated, firstly, the driving wheel 8 drives the driven wheel 4 to rotate through the toothed ring 6, the driven wheel 4 drives the clamping block 7 to slide upwards through the threaded rod 5, after the clamping block 7 is contacted with the fixed block 11, the fixed block 11 is driven to slide upwards, after the fixed rod 16 is separated from the clamping rod 15, the reset spring drives the clamping rod 15 to extend out to clamp the clamping block 7, the fixed block 11 drives the clamp 14 to slide towards a direction far away from the test tube groove 10 through the gear 12 and the rack 13, the threaded rod 5 continuously pushes the fixed block 11 out of the test tube groove 10, at the moment, an experimental test tube is placed at the top of the fixed block 11, the driving wheel 8 drives the driven wheel 4 to rotate through the toothed ring 6, the driven wheel 4 drives the fixed block 11 to slide downwards through the threaded rod 5, after teeth on the fixed block 11 are contacted with the gear 12, the rack 13 is driven to slide upwards through the gear 12, the rack, further fixing the test tube, thereby achieving the effect of preventing the test tube from colliding with the test tube slot 10 during centrifugation and damaging the test tube, when the fixed block 11 reaches the bottom of the test tube slot 10, the fixed rod 16 contacts with the clamping rod 15 to separate the clamping rod 15 from the clamping block 7, the driving wheel 8 continues to drive the threaded rod 5 to descend to separate from the rotating disc 9, then the motor 3 is started to drive the rotating disc 9 to rotate, the biological cells in the test tube are centrifugally separated, after the rotating disc 9 stops at the original position, the driving wheel 8 drives the threaded rod 5 to ascend through the toothed ring 6 and the gear 12 to push the fixed block 11 out of the test tube slot 10, thereby achieving the effect of conveniently observing the progress of cell separation in the test tube, avoiding bacterial pollution caused by artificial contact with the test tube, and the threaded rod 5 drives the test tube at the top of the fixed block 11 to slowly ascend at a uniform speed, avoiding the form of cell separation in the test, the observation effect is better.
In conclusion, this biological cell separator convenient to get and put test tube, through on putting the experiment test tube into the fixed block 11 of test tube groove 10, action wheel 8 passes through ring gear 6 and drives and rotate from driving wheel 4, from driving wheel 4 through threaded rod 5 drive fixed block 11 lapse, tooth and gear 12 contact back on the fixed block 11, drive rack 13 through gear 12 and upwards slide, rack 13 drives anchor clamps 14 through chute and slider and slides to the direction that is close to the test tube, and then it is fixed with the test tube, thereby reached and prevented that the test tube from colliding with test tube groove 10 when the centrifugation, the effect of harm leads to the fact to the test tube.
Action wheel 8 passes through ring gear 6 and drives from driving wheel 4 and rotate, from driving wheel 4 through threaded rod 5 drive fixture block 7 upwards sliding, after fixture block 7 and fixed block 11 contact, can drive fixed block 11 upwards sliding, fixed block 11 drives anchor clamps 14 through gear 12 and rack 13 and slides towards the direction of keeping away from the test tube, separate with the test tube, threaded rod 5 continues with 11 ejecting test tube grooves 10 of fixed block, thereby reached the effect of being convenient for carry out the observation to the progress of cell separation in the test tube, avoided the artificial contact test tube to cause bacterial contamination, and threaded rod 5 drives the test tube at the fixed block 11 top at the uniform velocity and slowly rises, the form of cell separation in having avoided the test tube receives external force and changes, make the observation effect better, application scope is more extensive.
Having shown and described embodiments of the present invention, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in the embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. The utility model provides a biological cell separator convenient to get and put test tube, includes box (1), its characterized in that: the test tube box is characterized in that a motor (3) and six fixed cylinders (2) are fixedly connected to the inner bottom wall of the box body (1), the tops of the six fixed cylinders (2) are connected with a driven wheel (4) in a rotating mode, a threaded rod (5) is inserted into the driven wheel (4), a toothed ring (6) is connected to the box body (1) in a rotating mode, clamping blocks (7) are fixedly connected to the tops of the threaded rods (5), a driving wheel (8) is arranged on the inner rear wall of the toothed ring (6) in a rotating mode, a rotating disc (9) is connected to the top of the motor (3) in a rotating mode, six test tube grooves (10) are formed in the top of the rotating disc (9), fixing blocks (11) are movably connected to the bottoms of the six test tube grooves (10), and a gear (12) and a clamp (14) are rotatably connected to one side, away from the center of the rotating disc (9), and one side, close to, one side that fixed block (11) were kept away from in gear (12) all is provided with rack (13), six the inside of fixed block (11) all is provided with two kellies (15), six two dead levers (16) of the equal fixedly connected with of inner diapire of test-tube slot (10).
2. The device for separating biological cells, which is convenient for taking and placing test tubes according to claim 1, wherein: the toothed ring (6) is meshed with the driving wheel (8) and the six driven wheels (4).
3. The device for separating biological cells, which is convenient for taking and placing test tubes according to claim 1, wherein: and teeth are arranged on one side of the fixed block (11) far away from the center of the rotating disc (9) and one side of the fixed block close to the center of the rotating disc (9) and are meshed with the gear (12).
4. The device for separating biological cells, which is convenient for taking and placing test tubes according to claim 1, wherein: the rack (13) is meshed with the gear (12).
5. The device for separating biological cells, which is convenient for taking and placing test tubes according to claim 1, wherein: the rack (13) penetrates through the clamp (14), inclined grooves are formed in the inner walls of the two sides, in contact with the rack (13), of the clamp (14), two sliding blocks are arranged outside the rack (13), and the sliding blocks are located in the inclined grooves.
6. The device for separating biological cells, which is convenient for taking and placing test tubes according to claim 1, wherein: the equal fixedly connected with reset spring in one side that kelly (15) carried on the back mutually, and the bottom of kelly (15) all is provided with the spout.
7. The device for separating biological cells, which is convenient for taking and placing test tubes according to claim 1, wherein: sponge cushions are arranged on the opposite sides of the clamps (14).
CN202011022082.1A 2020-09-25 2020-09-25 Biological cell separation device convenient to get and put test tube Withdrawn CN112175805A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011022082.1A CN112175805A (en) 2020-09-25 2020-09-25 Biological cell separation device convenient to get and put test tube

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011022082.1A CN112175805A (en) 2020-09-25 2020-09-25 Biological cell separation device convenient to get and put test tube

Publications (1)

Publication Number Publication Date
CN112175805A true CN112175805A (en) 2021-01-05

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112628357A (en) * 2021-02-15 2021-04-09 杭州天微基因科技有限公司 A gear box for nucleic acid extraction
CN113406319A (en) * 2021-06-25 2021-09-17 吉林大学 Division of endocrinology nurse is with urine sugar detection device
CN116040098A (en) * 2022-12-30 2023-05-02 吉林省医疗器械检验研究院(吉林省医药医疗器械洁净环境监测中心、吉林省医疗器械质量认证中心) Medicine inspection sampler that leakproofness is good

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112628357A (en) * 2021-02-15 2021-04-09 杭州天微基因科技有限公司 A gear box for nucleic acid extraction
CN113406319A (en) * 2021-06-25 2021-09-17 吉林大学 Division of endocrinology nurse is with urine sugar detection device
CN116040098A (en) * 2022-12-30 2023-05-02 吉林省医疗器械检验研究院(吉林省医药医疗器械洁净环境监测中心、吉林省医疗器械质量认证中心) Medicine inspection sampler that leakproofness is good
CN116040098B (en) * 2022-12-30 2023-09-01 吉林省医疗器械检验研究院(吉林省医药医疗器械洁净环境监测中心、吉林省医疗器械质量认证中心) Medicine inspection sampler that leakproofness is good

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Application publication date: 20210105