CN112168870A - Traditional Chinese medicine cough and asthma paste and preparation method thereof - Google Patents

Traditional Chinese medicine cough and asthma paste and preparation method thereof Download PDF

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Publication number
CN112168870A
CN112168870A CN201910588767.3A CN201910588767A CN112168870A CN 112168870 A CN112168870 A CN 112168870A CN 201910588767 A CN201910588767 A CN 201910588767A CN 112168870 A CN112168870 A CN 112168870A
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chinese medicine
traditional chinese
asthma
hot melt
melt adhesive
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王金文
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Henan Chungli Biotechnology Co ltd
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Henan Chungli Biotechnology Co ltd
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
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Abstract

The invention relates to a traditional Chinese medicine cough and asthma plaster and a preparation method thereof, wherein the traditional Chinese medicine cough and asthma plaster is prepared from the following raw materials, by weight, 15-18g of frosted mulberry leaf, 25-30g of white mustard seed, 25-30g of ephedra, 15-20g of asarum, 15-20g of euphorbia kansui, 15-20g of raw radix aconiti agrestis, 15-20g of radix angelicae, 25-30g of folium artemisiae argyi, 15-20g of saponin, 15-20g of black pepper, 600g of hot melt adhesive and 5-7g of vanillyl butyl ether. The invention has the advantages of improving clinical symptoms of cough, phlegm, asthma and the like, improving exercise tolerance, improving life quality and reducing the number of acute attack times per year, and is particularly suitable for patients in the stable period of chronic obstructive pulmonary disease and the remission period of asthma.

Description

Traditional Chinese medicine cough and asthma paste and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine cough and asthma paste and a preparation method thereof.
Background
Chronic obstructive pulmonary disease (chronic obstructive pulmonary disease) is characterized by an incompletely reversible airflow limitation, which is often progressively aggravated and is often associated with an abnormal inflammatory response of the lungs to harmful gases or particles such as cigarette smoke. Chronic obstruction of the lung mainly affects the lungs, but can also cause systemic adverse effects. The chronic obstructive pulmonary disease is mainly clinically manifested by chronic cough, expectoration, chest distress, shortness of breath and dyspnea, the dyspnea is a sign symptom of the chronic obstructive pulmonary disease, appears only in labor at the early stage, and is also short in breath during daily activities and even rest along with the gradual decline of lung functions, so that the life quality of patients is seriously affected. The chronic obstructive pulmonary disease has the disadvantages of a large number of patients, high mortality rate and heavy social and economic burden, becomes an important public health problem, and is the fourth cause of death in the world at present. In China, chronic obstructive pulmonary disease is also an important chronic respiratory disease seriously harming the physical health of people, the morbidity of the chronic obstructive pulmonary disease of people over 40 years old accounts for 8.2 percent, the mortality of the chronic obstructive pulmonary disease accounts for the 1 st chronic disease mortality in rural areas in China, and the chronic obstructive pulmonary disease brings huge burden to patients, families and society.
Modern medical treatment for chronic obstructive pulmonary disease comprises inhalation of glucocorticoid and/or bronchodilator, oral expectorant, antioxidant, etc., administration of antibiotic treatment when combined with bacterial infection, administration of long-term family oxygen therapy for treating chronic respiratory failure and heart failure, and treatment for correcting heart failure. In addition, rehabilitation therapy, surgical volume reduction and the like exist, but the current treatment means cannot change the natural course of the chronic obstructive pulmonary disease and cannot prevent and reverse the progress trend of the course of the disease.
The traditional Chinese medicine is mostly described in the sections of cough, asthma syndrome, lung distention and phlegm-fluid retention. The traditional Chinese medicine holds that the disease is caused by long-term chronic cough and asthma with reversed flow of qi, repeated attack, long-term lung, spleen and kidney deficiency, and accumulation of phlegm and blood stasis. The traditional Chinese medicine treatment selects different prescriptions according to different syndrome types of patients with syndrome differentiation, the dosage forms are decoction, powder or pill, and the like, but the patients are difficult to persist in long-term oral treatment due to long-term chronic obstructive pulmonary disease course.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine cough and asthma paste and a preparation method thereof.
The above object of the present invention is achieved by the following technical solutions:
a traditional Chinese medicine cough and asthma plaster is prepared from the following raw materials, by weight, 15-18g of frosted mulberry leaf, 25-30g of white mustard seed, 25-30g of ephedra herb, 15-20g of asarum, 15-20g of euphorbia kansui root, 15-20g of raw radix aconiti agrestis, 15-20g of radix angelicae, 25-30g of folium artemisiae argyi, 15-20g of saponin, 15-20g of black pepper, 600g of hot melt adhesive and 5-7g of vanillyl butyl ether.
Preferably, the traditional Chinese medicine cough and asthma paste is prepared from the following raw materials, by weight, 15g of frosted mulberry leaf, 25g of white mustard seed, 25g of ephedra herb, 15g of asarum, 15g of euphorbia kansui, 15g of raw radix aconiti agrestis, 15g of radix angelicae, 25g of folium artemisiae argyi, 15g of Chinese honeylocust fruit, 15g of black pepper, 500g of hot melt adhesive and 5g of vanillyl butyl ether.
Preferably, the traditional Chinese medicine cough and asthma paste is prepared from the following raw materials, by weight, 18g of frosted mulberry leaf, 30g of white mustard seed, 30g of ephedra herb, 20g of asarum, 20g of euphorbia kansui, 20g of unprocessed radix aconiti agrestis, 20g of radix angelicae, 30g of folium artemisiae argyi, 20g of Chinese honeylocust fruit, 20g of black pepper, 600g of hot melt adhesive and 7g of vanillyl butyl ether.
Preferably, the traditional Chinese medicine cough and asthma paste is prepared from the following raw materials, by weight, 17g of frosted mulberry leaf, 28g of white mustard seed, 28g of ephedra herb, 18g of asarum, 18g of euphorbia kansui, 18g of unprocessed radix aconiti kusnezoffii, 18g of radix angelicae, 28g of folium artemisiae argyi, 18g of saponin, 18g of black pepper, 550g of hot melt adhesive and 6g of vanillyl butyl ether.
A preparation method of a traditional Chinese medicine cough and asthma paste comprises the following steps:
(1) pulverizing folium Mori, semen Sinapis Albae, herba Ephedrae, herba asari, radix kansui, radix Aconiti Kusnezoffii, radix Angelicae Dahuricae, folium Artemisiae Argyi, fructus Gleditsiae Abnormalis, and fructus Piperis with superfine pulverizer, breaking cell wall, and sieving with 100 mesh sieve to obtain Chinese medicinal powder;
(2) heating the hot melt adhesive with an iron pot with slow fire until the hot melt adhesive is melted, then adding the traditional Chinese medicine powder prepared in the step (1) into the hot melt adhesive, and uniformly stirring, and then adding vanillyl butyl ether, and uniformly stirring to obtain a paste;
(3) adding a plaster dripping machine into the paste obtained in the step (2), and obtaining the plaster according to the required grams of mud flat.
Preferably, the temperature of the hot melt adhesive is not more than 110 ℃ during the process of heating to melt.
Preferably, the Chinese medicine powder obtained in the step (2) is slowly placed on the strainer a little by a little, the strainer is slowly shaken by hands to be uniformly and slowly added into the hot melt adhesive in the pot, and the Chinese medicine powder is stirred while being placed.
The traditional Chinese medicine used by the invention has the following medicinal properties:
frosted mulberry leaves: bitter and sweet in taste and cold in nature, and has the effects of dispelling wind and heat, clearing lung-heat, moistening dryness, suppressing liver yang, clearing liver-heat, improving eyesight, cooling blood and stopping bleeding;
white mustard seed: pungent taste and warm nature, and has effects of benefiting qi for eliminating phlegm, relieving swelling, resolving hard mass, dredging collaterals and relieving pain;
herba ephedrae: has pungent, slightly bitter and warm nature, and has effects of inducing sweat, dispelling cold, dispersing lung qi, relieving asthma, inducing diuresis, and relieving swelling;
asarum: has pungent taste and warm nature, and has effects of expelling pathogenic wind, dispelling cold, promoting diuresis, inducing resuscitation, and treating wind-cold headache, nasosinusitis, odontalgia, phlegm and fluid retention cough, and rheumatalgia;
euphorbia kansui: bitter taste, cold nature, and purgation and retention of water, and can be used for treating edema, abdominal dropsy, phlegm and fluid accumulation, reversed flow of qi, cough and asthma, and constipation;
raw radix aconiti: is bitter and pungent in taste, warm in nature, has effects of dispelling pathogenic wind, removing dampness, warming channels and relieving pain, and can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, and cold hernia pain;
raw kusnezoff monkshood root: is pungent, bitter and hot in taste, and has the effects of dispelling pathogenic wind, removing dampness, warming channels, dispelling cold, and relieving swelling and pain;
radix angelicae: the medicine has pungent taste and warm nature, enters lung, spleen and stomach channels, and has the effects of relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging nasal orifice, eliminating dampness, stopping leukorrhagia, and relieving swelling and pus discharge;
folium artemisiae argyi: the medicine is pungent and bitter in taste and warm in nature, and has the effects of warming channels, stopping bleeding, dispelling cold, relieving pain, eliminating dampness and relieving itching;
and (2) Chinese honeylocust fruit: has pungent taste and warm nature, and has effects of eliminating phlegm, relieving cough, and opening and closing orifices;
black pepper: pungent taste and warm nature, and has the actions of warming the middle-jiao and descending qi, resolving phlegm and removing toxicity.
In conclusion, the beneficial technical effects of the invention are as follows:
the traditional Chinese medicine powder is subjected to ultramicro wall breaking, the particle size can reach 300 meshes, the medicine effect is better to be absorbed, the plaster is not carbonized at low temperature, does not contain lead and mercury, has better effect and is healthier.
Detailed Description
The present invention will be described in further detail with reference to examples.
Example 1:
the invention discloses a traditional Chinese medicine cough and asthma plaster which is prepared from the following raw materials, by weight, 15g of frosted mulberry leaf, 25g of white mustard seed, 25g of ephedra herb, 15g of asarum, 15g of euphorbia kansui, 15g of raw radix aconiti agrestis, 15g of radix angelicae, 25g of folium artemisiae argyi, 15g of saponin, 15g of black pepper, 500g of hot melt adhesive and 5g of vanillyl butyl ether.
A preparation method of a traditional Chinese medicine cough and asthma paste comprises the following steps:
(1) pulverizing folium Mori, semen Sinapis Albae, herba Ephedrae, herba asari, radix kansui, radix Aconiti Kusnezoffii, radix Angelicae Dahuricae, folium Artemisiae Argyi, fructus Gleditsiae Abnormalis, and fructus Piperis with superfine pulverizer, breaking cell wall, and sieving with 100 mesh sieve to obtain Chinese medicinal powder;
(2) heating the hot melt adhesive with an iron pot with slow fire until the hot melt adhesive is melted, then adding the traditional Chinese medicine powder prepared in the step (1) into the hot melt adhesive, and uniformly stirring, and then adding vanillyl butyl ether, and uniformly stirring to obtain a paste;
(3) adding a plaster dripping machine into the paste obtained in the step (2), and obtaining the plaster according to the required grams of mud flat.
The temperature of the hot melt adhesive is not more than 110 ℃ in the process of heating to melt.
Slowly placing the Chinese medicinal powder obtained in the step (2) on the strainer a little by a little, slowly shaking the strainer by hands to uniformly and slowly add the Chinese medicinal powder into the hot melt adhesive in the pot, and stirring while adding the Chinese medicinal powder.
Example 2:
the invention discloses a traditional Chinese medicine cough and asthma paste which is prepared from the following raw materials, by weight, 18g of frosted mulberry leaf, 30g of white mustard seed, 30g of ephedra herb, 20g of asarum, 20g of euphorbia kansui, 20g of unprocessed radix aconiti kusnezoffii, 20g of angelica dahurica, 30g of folium artemisiae argyi, 20g of Chinese honeylocust fruit, 20g of black pepper, 600g of hot melt adhesive and 7g of vanillyl butyl ether.
A preparation method of a traditional Chinese medicine cough and asthma paste comprises the following steps:
(1) pulverizing folium Mori, semen Sinapis Albae, herba Ephedrae, herba asari, radix kansui, radix Aconiti Kusnezoffii, radix Angelicae Dahuricae, folium Artemisiae Argyi, fructus Gleditsiae Abnormalis, and fructus Piperis with superfine pulverizer, breaking cell wall, and sieving with 100 mesh sieve to obtain Chinese medicinal powder;
(2) heating the hot melt adhesive with an iron pot with slow fire until the hot melt adhesive is melted, then adding the traditional Chinese medicine powder prepared in the step (1) into the hot melt adhesive, and uniformly stirring, and then adding vanillyl butyl ether, and uniformly stirring to obtain a paste;
(3) adding a plaster dripping machine into the paste obtained in the step (2), and obtaining the plaster according to the required grams of mud flat.
The temperature of the hot melt adhesive is not more than 110 ℃ in the process of heating to melt.
Slowly placing the Chinese medicinal powder obtained in the step (2) on the strainer a little by a little, slowly shaking the strainer by hands to uniformly and slowly add the Chinese medicinal powder into the hot melt adhesive in the pot, and stirring while adding the Chinese medicinal powder.
Example 3:
the invention discloses a traditional Chinese medicine cough and asthma plaster which is prepared from the following raw materials, by weight, 17g of frosted mulberry leaf, 28g of white mustard seed, 28g of ephedra herb, 18g of asarum, 18g of euphorbia kansui, 18g of unprocessed radix aconiti kusnezoffii, 18g of angelica dahurica, 28g of folium artemisiae argyi, 18g of saponin, 18g of black pepper, 550g of hot melt adhesive and 6g of vanillyl butyl ether.
A preparation method of a traditional Chinese medicine cough and asthma paste comprises the following steps:
(1) pulverizing folium Mori, semen Sinapis Albae, herba Ephedrae, herba asari, radix kansui, radix Aconiti Kusnezoffii, radix Angelicae Dahuricae, folium Artemisiae Argyi, fructus Gleditsiae Abnormalis, and fructus Piperis with superfine pulverizer, breaking cell wall, and sieving with 100 mesh sieve to obtain Chinese medicinal powder;
(2) heating the hot melt adhesive with an iron pot with slow fire until the hot melt adhesive is melted, then adding the traditional Chinese medicine powder prepared in the step (1) into the hot melt adhesive, and uniformly stirring, and then adding vanillyl butyl ether, and uniformly stirring to obtain a paste;
(3) adding a plaster dripping machine into the paste obtained in the step (2), and obtaining the plaster according to the required grams of mud flat.
The temperature of the hot melt adhesive is not more than 110 ℃ in the process of heating to melt.
Slowly placing the Chinese medicinal powder obtained in the step (2) on the strainer a little by a little, slowly shaking the strainer by hands to uniformly and slowly add the Chinese medicinal powder into the hot melt adhesive in the pot, and stirring while adding the Chinese medicinal powder.
Clinical data:
1. case selection:
selecting 200 patients with cough and asthma for observation, and randomly dividing the patients into a treatment group and a control group;
in the treatment group 100, 50 males and 50 females are 20-70 years old at 50 years old;
in a control group 100, 50 males and 50 females are 20-70 years old at 50 years old;
the disease course and the severity of symptoms of the two groups of cases of the treatment group and the control group are basically consistent, have no obvious difference and are comparable.
2. Selecting the medicines:
the traditional Chinese medicine cough and asthma plaster is externally applied to a treatment group, 1 time is taken every day, 1 plaster is applied every time, 1 day is 1 treatment course, 3-4 treatment courses are continuously performed, and the dosage is increased according to the advice of patients with serious illness;
the control group adopts conventional treatment method of oral Chinese medicine or western medicine.
3. And (3) judging the curative effect:
(1) and (3) curing: the cough and asthma symptoms disappear completely, and the body recovers as normal;
(2) the effect is shown: the cough and asthma symptoms are obviously disappeared and obviously alleviated;
(3) the method has the following advantages: the cough and asthma symptoms basically disappear and are relieved;
(4) and (4) invalidation: the symptoms of cough and asthma are not improved or aggravated by treatment.
4. As a result:
number of examples Cure of disease Show effect Is effective Invalidation Cure rate Total effective rate
Treatment group 100 95 2 1 2 95% 98%
Control group 100 80 10 2 8 80 92%
The results show that the cure rate and the total effective rate of the treatment group are higher than those of the control group.
The traditional Chinese medicine powder is subjected to ultramicro wall breaking, the particle size can reach 300 meshes, the medicine effect is better to be absorbed, the plaster is not carbonized at low temperature, does not contain lead and mercury, has better effect and is healthier.
The embodiments of the present invention are preferred embodiments of the present invention, and the scope of the present invention is not limited by these embodiments, so: all equivalent changes made according to the structure, shape and principle of the invention are covered by the protection scope of the invention.

Claims (7)

1. The traditional Chinese medicine cough and asthma paste is characterized by being prepared from the following raw materials in parts by weight: 15-18g of frosted mulberry leaf, 25-30g of white mustard seed, 25-30g of ephedra herb, 15-20g of asarum, 15-20g of euphorbia kansui, 15-20g of unprocessed radix aconiti kusnezoffii, 15-20g of angelica dahurica, 25-30g of folium artemisiae argyi, 15-20g of Chinese honeylocust fruit, 15-20g of black pepper, 500g of hot melt adhesive and 600g of vanillyl butyl ether.
2. The traditional Chinese medicine cough and asthma paste as claimed in claim 1, which is characterized in that: the traditional Chinese medicine cough and asthma paste is prepared from the following raw materials, by weight, 15g of frosted mulberry leaf, 25g of white mustard seed, 25g of ephedra herb, 15g of asarum, 15g of euphorbia kansui, 15g of raw radix aconiti, 15g of raw kusnezoff monkshood root, 15g of angelica dahurica, 25g of folium artemisiae argyi, 15g of Chinese honeylocust fruit, 15g of black pepper, 500g of hot melt adhesive and 5g of vanillyl butyl ether.
3. The traditional Chinese medicine cough and asthma paste as claimed in claim 1, which is characterized in that: the traditional Chinese medicine cough and asthma paste is prepared from the following raw materials, by weight, 18g of frosted mulberry leaf, 30g of white mustard seed, 30g of ephedra herb, 20g of asarum, 20g of euphorbia kansui, 20g of unprocessed radix aconiti kusnezoffii, 20g of radix angelicae, 30g of folium artemisiae argyi, 20g of saponin, 20g of black pepper, 600g of hot melt adhesive and 7g of vanillyl butyl ether.
4. The traditional Chinese medicine cough and asthma paste as claimed in claim 1, which is characterized in that: the traditional Chinese medicine cough and asthma paste is prepared from the following raw materials, by weight, 17g of frosted mulberry leaf, 28g of white mustard seed, 28g of ephedra herb, 18g of asarum, 18g of euphorbia kansui, 18g of unprocessed radix aconiti kusnezoffii, 18g of radix angelicae, 28g of folium artemisiae argyi, 18g of saponin, 18g of black pepper, 550g of hot melt adhesive and 6g of vanillyl butyl ether.
5. The preparation method of the traditional Chinese medicine cough and asthma paste as claimed in claim 1, which is characterized by comprising the following steps:
(1) pulverizing folium Mori, semen Sinapis Albae, herba Ephedrae, herba asari, radix kansui, radix Aconiti Kusnezoffii, radix Angelicae Dahuricae, folium Artemisiae Argyi, fructus Gleditsiae Abnormalis, and fructus Piperis with superfine pulverizer, breaking cell wall, and sieving with 100 mesh sieve to obtain Chinese medicinal powder;
(2) heating the hot melt adhesive with an iron pot with slow fire until the hot melt adhesive is melted, then adding the traditional Chinese medicine powder prepared in the step (1) into the hot melt adhesive, and uniformly stirring, and then adding vanillyl butyl ether, and uniformly stirring to obtain a paste;
(3) adding a plaster dripping machine into the paste obtained in the step (2), and obtaining the plaster according to the required grams of mud flat.
6. The traditional Chinese medicine cough and asthma paste according to claim 5, which is characterized in that: the temperature of the hot melt adhesive is not more than 110 ℃ in the process of heating to melt.
7. The traditional Chinese medicine cough and asthma paste according to claim 5, which is characterized in that: slowly placing the Chinese medicinal powder obtained in the step (2) on the strainer a little by a little, slowly shaking the strainer by hands to uniformly and slowly add the Chinese medicinal powder into the hot melt adhesive in the pot, and stirring while adding the Chinese medicinal powder.
CN201910588767.3A 2019-07-02 2019-07-02 Traditional Chinese medicine cough and asthma paste and preparation method thereof Pending CN112168870A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103169754A (en) * 2011-12-09 2013-06-26 上海市中医医院 Traditional Chinese medicinal composition for treating asthma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103169754A (en) * 2011-12-09 2013-06-26 上海市中医医院 Traditional Chinese medicinal composition for treating asthma

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张奇文等: "《中国膏敷疗法 第2版》", 31 January 2018, 中国医药科技出版社 *

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