CN112159754B

CN112159754B - Exosome tumor vaccine preparation equipment

Info

Publication number: CN112159754B
Application number: CN202011081535.8A
Authority: CN
Inventors: 冯文明; 崔戈; 田华妹
Original assignee: First Peoples Hospital of Huzhou
Current assignee: ZHEJIANG CENTRAL CORPORATION OF TECHNOLOGY AND TECHNOLOGY Co.,Ltd.
Priority date: 2020-10-12
Filing date: 2020-10-12
Publication date: 2021-09-03
Anticipated expiration: 2040-10-12
Also published as: CN112159754A

Abstract

The invention discloses an exosome tumor vaccine manufacturing device, which comprises a machine body, wherein a conical working cavity with an upward opening is arranged in the machine body, slide rods are slidably arranged on the left side wall and the right side wall of the conical working cavity, the lower side of each slide rod is rotatably connected with a hook claw through a torsion spring, a centrifugal barrel is rotatably connected between the slide rods on the left side and the right side, clamping grooves are symmetrically arranged on the left side and the right side of the bottom wall of the centrifugal barrel, the lower ends of the hook claws extend into the clamping grooves, a centrifugal cavity with an upward opening is arranged in the centrifugal barrel, a filter screen is fixedly connected in the centrifugal cavity, a movable pipe penetrating through the centrifugal barrel is slidably arranged on the bottom wall of the centrifugal cavity, the device is simple to operate, the device is movably communicated through the placement of a cover plate and a storage barrel, so that the limitation on the centrifugal barrel is removed, the movement of a collecting pipe frame is controlled through the transmission alternation between a rotating shaft and a transmission shaft, and the intermittent movement of the movable pipe is synchronously controlled, thereby collecting and packaging the exosome cells at different stages and facilitating the vaccine production.

Description

Exosome tumor vaccine preparation equipment

Technical Field

The invention relates to the technical field related to vaccine preparation, in particular to exosome tumor vaccine preparation equipment.

Background

The tumor problem puzzles people's very serious disease, and scientists discover through the experiment now that the exosome of tumor can play huge effect in the transfer process of tumor, therefore tumour bacterin accessible exosome preparation, but current exosome extraction methods are more, and the effect differs, can not be suitable carry out extraction work to tumour exosome, and is inefficient, and the exosome after the separation is collected the separation comparatively loaded down with trivial details moreover.

Disclosure of Invention

The invention aims to solve the technical problem of providing an exosome tumor vaccine manufacturing device, and solves the problems of low exosome separation efficiency and difficult exosome collection.

The invention is realized by the following technical scheme.

The invention relates to an exosome tumor vaccine manufacturing device, which comprises a machine body, wherein a conical working cavity with an upward opening is arranged in the machine body, slide rods are slidably arranged on the left side wall and the right side wall of the conical working cavity, the lower side of each slide rod is rotatably connected with a hook claw through a torsion spring, a centrifugal barrel is rotatably connected between the slide rods on the left side and the right side, clamping grooves are symmetrically arranged on the left side and the right side of the bottom wall of the centrifugal barrel, the lower ends of the hook claws extend into the clamping grooves, a centrifugal cavity with an upward opening is arranged in the centrifugal barrel, a filter screen is fixedly connected in the centrifugal cavity, a movable tube penetrating through the centrifugal barrel is slidably arranged on the bottom wall of the centrifugal cavity, a supporting plate is fixedly connected outside the centrifugal barrel, the supporting plate is connected with the bottom wall of the centrifugal barrel through a spring, fixed rods are respectively fixedly arranged on the left side and the right side of the front wall and the rear wall of the centrifugal cavity, and sliding plates are symmetrically matched in the centrifugal cavity in a sliding mode, the slide plate is arranged on the left side and the right side and used for sealing the movable pipe, the upper side of the slide plate is rotatably connected with a swing rod, the upper side of the swing rod supports the filter screen, the swing rod is provided with a guide slot which is penetrated through from front to back, the fixed rod penetrates and is in sliding fit with the guide slot, the top wall of the centrifugal barrel is rotatably connected with a cover plate outside the machine body, the upper side of the cover plate is in sliding connection with a storage barrel, a storage cavity is arranged in the storage barrel, the lower side of the storage cavity is communicated with a discharge port which penetrates through the storage barrel, the cover plate is provided with a connecting port which penetrates through the cover plate at the lower side of the discharge port, the left side wall and the right side wall of the connecting port are symmetrically provided with chutes, a partition plate is arranged on the wall body between the chutes and the connecting port in a sliding manner, the partition plate is connected with the inner wall of the chutes through springs, the top wall of the chutes is provided with L-shaped inclined rods which extend out to contact the cover plate and the storage barrel, l shape bevel lever in the spout with the baffle contact, lateral wall symmetry is equipped with the opening orientation around the toper working chamber the slot rolling of centrifugation bucket, toper working chamber downside is equipped with the belt chamber, the front and back side the slot rolling with wall body between the belt chamber rotates installs the roller shaft, the roller shaft in fixedly connected with gyro wheel in the slot rolling, the gyro wheel with centrifugation bucket roll connection, the front and back side the roller shaft in the belt intracavity is connected through power belt transmission.

Preferably, the wall body between toper working chamber and the belt chamber is equipped with the transmission chamber, slidable mounting has the collection pipe support on the toper working chamber front and back wall, divide equally on the collection pipe support and be equipped with the ascending collection chamber of opening, transmission chamber with wall body rotation between the toper working chamber installs transmission shaft and pivot, the pivot is located collection pipe support left side, the transmission shaft is located collection pipe support right side, the transmission shaft with the pivot is in the transmission chamber is connected through connecting the belt transmission, the pivot is in toper working chamber fixedly connected with impels gear and L shape pole, impel gear with the meshing of collection pipe support is connected, L shape pole with the backup pad contacts, the transmission shaft in toper working chamber splined connection has the spline sleeve, fixedly connected with conical surface gyro wheel on the spline sleeve outer wall, the spline sleeve is connected with a supporting push plate on the upper side of the conical roller in a rotating mode, the supporting push plate is in contact with the supporting plate, and the supporting plate is connected with the bottom wall of the conical working cavity through a spring.

Preferably, the collecting pipe frame in collect the chamber right side and be equipped with the opening groove of accomodating to the right, it has the push rod to accomodate inslot slidable mounting, the push rod with conical surface gyro wheel is connected, it is equipped with the forward connection spout of opening to collect chamber back side wall, it has link block to connect slidable mounting in the spout, the link block front side is connected with through the turn-round and stretches into collect the connection pivot in chamber, connect the pivot in collect intracavity fixedly connected with upset apron, link block right side fixedly connected with connects the rope, connect rope sliding fit collect the pipe frame right side wall and stretch out the collecting pipe frame, it stretches into to connect the rope right side accomodate groove fixed connection the push rod left end.

Preferably, a motor cavity is arranged on a wall body between the rolling groove on the rear side and the belt cavity, the roller shaft on the rear side is rotatably connected with the wall body between the rolling groove on the rear side and the belt cavity on the rear side, a motor is fixedly installed on the rear side wall of the motor cavity, the front side of the motor is in power connection with a worm motor shaft, the worm motor shaft and the roller shaft are connected through a linking bevel gear set, a transmission worm is rotatably installed on the wall body between the motor cavity and the conical working cavity, the transmission worm is in transmission connection with the motor cavity and the worm motor shaft through a linking belt, a linking worm wheel is fixedly connected in the transmission cavity of the transmission shaft, the transmission worm is in meshing connection with the linking worm wheel in the transmission cavity, a T-shaped rod is slidably installed on the wall body between the transmission cavity and the conical working cavity, and supporting rotating plates are rotatably installed on the front side and the rear side of the T-shaped rod in the transmission cavity, the front side and the rear side are connected through springs, and the supporting rotating plates are in contact with the connecting belts.

Preferably, the left and right side walls of the conical working cavity are symmetrically provided with lifting cavities, the left and right sides of the conical working cavity are rotatably provided with linking shafts, the linking shafts are fixedly connected with driven worm gears in the motor cavity, the driven worm gears are meshed and connected with the worm motor shaft, the linking shafts are fixedly connected with upgrading arc gears in the lifting cavities, the top wall of the lifting cavity is slidably provided with lifting racks extending out of the machine body, the lifting racks are connected with the bottom wall of the lifting cavity through springs, the lifting racks are meshed and connected with the upgrading arc gears, the side of the cover plate away from the connecting port in the sliding chute is provided with transition grooves with downward openings, the left and right side walls of the transition grooves are rotatably provided with connecting shafts, the connecting shafts are fixedly connected with driven wheels and chain wheels, and pull ropes are wound and connected on the chain wheels, the pull rope is in sliding fit with the wall body between the transition groove and the sliding groove, the pull rope is fixedly connected with the partition board in the sliding groove, and the lifting rack is meshed with the driven wheel.

Preferably, the toper working chamber with slide bar sliding fit department is equipped with the opening orientation the spacing groove of centrifugation bucket, the slide bar in spacing inslot fixedly connected with fixed block, the fixed block passes through spring coupling the spacing groove diapire, be equipped with the annular on the centrifugation bucket outer wall, control the side the slide bar in fixedly connected with fixture block in the apron.

The invention has the beneficial effects that: this device easy operation, place through apron and storage vat and make device activity intercommunication, thereby remove the restriction to the centrifugation bucket, transmission through between pivot and the transmission shaft is alternative, the pipe support activity is collected in control, and the intermittent type nature removal of synchronous control movable tube, thereby collect and encapsulate the exosome cell under the different stages, conveniently carry out the bacterin preparation, cooperate from driving wheel control baffle intermittent type nature activity through the lifting rack, thereby control catalyst gets into the centrifugal chamber, cooperation centrifugation bucket rotates the high-efficient separation exosome of centrifugal force and cell that produces, and the work efficiency is improved.

Drawings

In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the invention, and it is obvious for those skilled in the art that other drawings can be obtained based on these drawings without creative efforts.

FIG. 1 is a schematic structural diagram of an apparatus for preparing an exosome tumor vaccine according to an embodiment of the present invention;

FIG. 2 is an enlarged schematic view of the structure at A in FIG. 1 according to an embodiment of the present invention;

FIG. 3 is a schematic diagram of a partial cross-sectional structure at B-B in FIG. 1 according to an embodiment of the present invention;

FIG. 4 is an enlarged schematic view of the embodiment of the present invention at C in FIG. 1;

FIG. 5 is a schematic diagram of a partial cross-sectional structure at D-D in FIG. 1 according to an embodiment of the present invention.

Detailed Description

The invention will now be described in detail with reference to fig. 1-5, wherein for ease of description the orientations described hereinafter are now defined as follows: the up, down, left, right, and front-back directions described below correspond to the up, down, left, right, and front-back directions in the projection relationship of fig. 1 itself.

With reference to the accompanying drawings 1-5, an exosome tumor vaccine manufacturing device comprises a machine body 27, wherein a conical working chamber 28 with an upward opening is arranged in the machine body 27, sliding devices are arranged on the left side wall and the right side wall of the conical working chamber 28 and provided with a sliding rod 14, the lower side of the sliding rod 14 is connected with a hook claw 15 through a torsion spring in a rotating manner, a centrifugal barrel 29 is rotatably connected between the sliding rods 14 on the left side and the right side, the bottom wall of the centrifugal barrel 29 is bilaterally symmetrical and provided with clamping grooves 16, the lower end of the hook claw 15 extends into the clamping groove 16, a centrifugal chamber 40 with an upward opening is arranged in the centrifugal barrel 29, a filter screen 39 is fixedly connected in the centrifugal chamber 40, a movable pipe 63 penetrating through the centrifugal barrel 29 is slidably arranged on the bottom wall of the centrifugal chamber 40, a supporting plate 64 is fixedly connected outside the centrifugal barrel 29, the supporting plate 64 is connected with the bottom wall of the centrifugal barrel 29 through a spring, fixing rods 60 are fixedly arranged on the left side and the right side of the front and rear wall of the centrifugal chamber 40 respectively, the movable pipe 63 is symmetrically and sliding-fitted with sliding plates 75 in the centrifugal chamber 40, the sliding plates 75 on the left and right sides seal the movable pipe 63, the upper side of the sliding plate 75 is rotatably connected with a swing rod 62, the upper side of the swing rod 62 supports the filter screen 39, the swing rod 62 is provided with guide grooves 61 which are penetrated through from front to back, the fixed rod 60 is penetrated through and sliding-fitted with the guide grooves 61, the top wall of the centrifugal barrel 29 is rotatably connected with a cover plate 43 outside the machine body 27, the upper side of the cover plate 43 is slidably connected with a storage barrel 42, the storage chamber 41 is arranged in the storage barrel 42, the lower side of the storage chamber 41 is communicated with a discharge port 48 penetrating through the storage barrel 42, the cover plate 43 is provided with a connecting port 49 penetrating through the cover plate 43 at the lower side of the discharge port 48, sliding chutes 46 are symmetrically arranged in the left and right side walls of the connecting port 49, and a partition plate 45 is installed on the sliding wall body between the sliding chute 46 and the connecting port 49, baffle 45 passes through spring coupling the spout 46 inner wall, spout 46 roof slidable mounting has L shape inclined plane pole 47, L shape inclined plane pole 47 stretches out apron 43 with the storage vat 42 contact, L shape inclined plane pole 47 in the spout 46 with baffle 45 contact, the lateral wall symmetry is equipped with the opening orientation around the toper working chamber 28 the slot rolling 52 of centrifuge drum 29, toper working chamber 28 downside is equipped with belt chamber 22, the front and back side the slot rolling 52 with wall rotation between the belt chamber 22 installs roller shaft 51, roller shaft 51 in fixedly connected with gyro wheel 50 in the slot rolling 52, gyro wheel 50 with centrifuge drum 29 roll connection, the front and back side roller shaft 51 in connect through power belt 24 belt transmission in the belt chamber 22.

Beneficially, wall body between toper working chamber 28 and the belt chamber 22 is equipped with transmission chamber 26, slidable mounting has collection pipe support 55 on the toper working chamber 28 front and back wall, it is equipped with the ascending collection chamber 70 of opening equally to divide on the collection pipe support 55, transmission chamber 26 with wall body rotation between the toper working chamber 28 installs transmission shaft 25 and pivot 20, pivot 20 is located collection pipe support 55 left side, transmission shaft 25 is located collection pipe support 55 right side, transmission shaft 25 with pivot 20 in transmission chamber 26 through connecting belt 23 belt drive connection, pivot 20 in fixedly connected with impels curved gear 18 and L shape pole 17 in toper working chamber 28, impel curved gear 18 with collection pipe support 55 meshing connection, L shape pole 17 with the backup pad 64 contact, transmission shaft 25 in toper working chamber 28 internal spline connection has spline sleeve 66, the outer wall of the spline sleeve 66 is fixedly connected with a conical roller 76, the spline sleeve 66 is rotatably connected with a supporting push plate 65 on the upper side of the conical roller 76, the supporting push plate 65 is in contact with the supporting plate 64, and the supporting plate 64 is connected with the bottom wall of the conical working cavity 28 through a spring.

Beneficially, collect pipe support 55 in collect chamber 70 right side is equipped with opening right groove 69 of accomodating, it has push rod 68 to accomodate the interior sliding fit of groove 69, push rod 68 with conical surface gyro wheel 76 connects, collect chamber 70 back side wall is equipped with the forward connection spout 71 of opening, sliding fit has link block 73 in connecting spout 71, link block 73 front side rotates through the twisted ring to be connected with and stretches into collect chamber 70's connection pivot 74, connect pivot 74 in collect chamber 70 interior fixedly connected with flip cover 72, link block 73 right side fixedly connected with connects rope 67, connect rope 67 sliding fit collect pipe support 55 right side wall and stretch out collect pipe support 55, connect rope 67 right side to stretch into accomodate groove 69 fixed connection the push rod 68 left end.

Advantageously, a motor cavity 53 is formed in a wall body between the rolling groove 52 and the belt cavity 22 at the rear side, the roller shaft 51 at the rear side is rotatably connected with the motor cavity 53 and a wall body between the rolling groove 52 and the belt cavity 22 at the rear side, a motor 54 is fixedly installed on the rear side wall of the motor cavity 53, a worm motor shaft 58 is dynamically connected with the front side of the motor 54, the worm motor shaft 58 is connected with the roller shaft 51 through an engaging bevel gear set 57, a transmission worm 21 is rotatably installed on the wall body between the motor cavity 53 and the tapered working cavity 28, the transmission worm 21 is in belt transmission connection with the motor cavity 53 and the worm motor shaft 58 through an engaging belt 59, an engaging worm wheel 19 is fixedly connected in the transmission cavity 26 of the transmission shaft 25, the transmission worm 21 is in meshing connection with the engaging worm wheel 19 in the transmission cavity 26, a T-shaped rod 78 is slidably installed on the wall body between the transmission cavity 26 and the tapered working cavity 28, the top wall of the transmission cavity 26 is rotatably provided with a supporting rotating plate 77 at the front side and the rear side of the T-shaped rod 78, the supporting rotating plate 77 at the front side and the rear side are connected through a spring, and the supporting rotating plate 77 is contacted with the connecting belt 23.

Beneficially, the left and right side walls of the conical working cavity 28 are symmetrically provided with lifting cavities 32, the wall body between the lifting cavity 32 and the motor cavity 53 on the left and right sides is rotatably provided with a connecting shaft 31, the connecting shaft 31 is fixedly connected with a driven worm gear 56 in the motor cavity 53, the driven worm gear 56 is in meshed connection with the worm motor shaft 58, the connecting shaft 31 is fixedly connected with an upgrading arc gear 30 in the lifting cavity 32, the top wall of the lifting cavity 32 is slidably provided with a lifting rack 33 extending out of the machine body 27, the lifting rack 33 is connected with the bottom wall of the lifting cavity 32 through a spring, the lifting rack 33 is in meshed connection with the upgrading arc gear 30, the cover plate 43 is provided with a transition groove 36 with a downward opening on the side of the sliding groove 46 far away from the connecting port 49, the left and right side walls of the transition groove 36 are rotatably provided with connecting shafts 34, and a driven wheel 35 and a chain wheel 37 are fixedly, the chain wheel 37 is wound and connected with a pull rope 38, the pull rope 38 is in sliding fit with a wall body between the transition groove 36 and the sliding groove 46, the pull rope 38 is fixedly connected with the partition plate 45 in the sliding groove 46, and the lifting rack 33 is meshed and connected with the driven wheel 35.

Beneficially, the conical working chamber 28 and the sliding fit position of the sliding rod 14 are provided with a limiting groove 13 with an opening facing the centrifugal barrel 29, the sliding rod 14 is fixedly connected with a fixed block 12 in the limiting groove 13, the fixed block 12 is connected with the bottom wall of the limiting groove 13 through a spring, an annular groove 44 is arranged on the outer wall of the centrifugal barrel 29, and the sliding rod 14 is fixedly connected with a clamping block 11 in the cover plate 43 on the left side and the right side.

In an initial state, the cover plate 43 is separated from the storage barrel 42 and the centrifugal barrel 29, the connecting belt 23 is loosened, the lower side of the hook claw 15 extends into the clamping groove 16, the partition plate 45 seals the connecting port 49, the sliding plate 75 seals the movable pipe 63, and the L-shaped inclined plane rod 47 limits the movement of the partition plate 45;

when the centrifugal machine starts to work, the storage barrel 42 is buckled on the cover plate 43, the L-shaped bevel lever 47 moves downwards, the partition plate 45 can move, the cover plate 43 is placed on the centrifugal barrel 29 and drives the centrifugal barrel 29 to move downwards, the centrifugal barrel 29 drives the sliding rod 14 and the hook claw 15 to move downwards through the clamping block 11, the hook claw 15 turns over and is separated from the clamping groove 16, the motor 54 is started to drive the worm motor shaft 58 to rotate, the worm motor shaft 58 drives the rear side roller shaft 51 to rotate through the engaging bevel gear set 57, the rear side roller shaft 51 drives the front side roller shaft 51 to rotate through the power belt 24, the front side roller shaft 51 and the rear side roller shaft 51 drive the centrifugal barrel 29 to rotate through the rollers 50, meanwhile, the worm motor shaft 58 drives the connecting shaft 31 to rotate through the driven worm wheel 56, the connecting shaft 31 drives the left and right side upgrading arc gears 30 to control the lifting racks 33 to move, the upgrading racks 33 reciprocate up and down through the springs and the upgrading arc gears 30, the upgrading arc gears 30 drive the connecting shaft 34 to rotate through the driven wheels 35, the connecting shaft 34 drives the chain wheel 37 to rotate, the pull rope 38 is contracted and loosened to and fro, the pull rope 38 drives the partition plate 45 to be opened intermittently, the catalyst in the storage cavity 41 falls into the centrifugal cavity 40, the conical working cavity 28 is matched with the catalyst through centrifugal force to separate exosomes from cancer cells, the exosomes are filtered by the filter screen 39 to fall into the bottom of the centrifugal cavity 40, the collecting pipe frame 55 is extended into the conical working cavity 28, the collecting pipe frame 55 is contacted with the T-shaped rod 78, the T-shaped rod 78 moves downwards to drive the front and rear side supporting rotating plates 77 to rotate, the supporting rotating plates 77 tension the connecting belt 23, the worm motor shaft 58 drives the transmission worm 21 to rotate through the connecting belt 59, the transmission worm 21 drives the transmission shaft 25 to rotate through the connecting worm wheel 19, the transmission shaft 25 drives the rotating shaft 20 to rotate through the connecting belt 23, the rotating shaft 20 drives the pushing arc-shaped gear 18 and the L-shaped rod 17 to rotate, the supporting plate 64 drives the movable tube 63 to move upwards, the movable tube 63 drives the sliding plate 75 to move upwards, the sliding plate 75 is matched with the swing rod 62 to overturn and slide, the movable tube 63 is communicated, exosomes on the bottom wall of the centrifugal cavity 40 falls into the collection cavity 70 through the movable tube 63, the L-shaped rod 17 is separated from the support plate 64, the support plate 64 moves downwards to drive the support push plate 65 to move, the support push plate 65 drives the conical roller 76 to move downwards through the spline sleeve 66, the transmission shaft 25 drives the conical roller 76 to rotate through the spline sleeve 66, the conical roller 76 drives the push rod 68 to slide leftwards in the process of rotating and moving downwards, the push rod 68 drives the connecting slider 73 to move rightwards through the connecting rope 67, the connecting slider 73 drives the turnover cover plate 72 to slide through the connecting rotating shaft 74, the turnover cover plate 72 slides and rotates, the turnover cover plate 72 seals the collection cavity 70, the arc gear 18 is pushed to contact with the collection pipe frame 55 to drive the collection pipe frame 55 to slide, and the movable pipe 63 contacts with the next collection cavity 70.

After the work is finished, the motor 54 is turned off, the collecting pipe frame 55 is pulled out, the cover plate 43 and the storage bucket 42 are taken down, and the device is restored to the initial state.

The above embodiments are merely illustrative of the technical ideas and features of the present invention, and the purpose thereof is to enable those skilled in the art to understand the contents of the present invention and implement the present invention, and not to limit the protection scope of the present invention. All equivalent changes and modifications made according to the spirit of the present invention should be covered within the protection scope of the present invention.

Claims

1. An exosome tumor vaccine preparation equipment, includes the organism, its characterized in that: a conical working cavity with an upward opening is arranged in the machine body, slide bars are arranged on the left side wall and the right side wall of the conical working cavity in a sliding manner, the lower side of each slide bar is rotatably connected with a hook claw through a torsion spring, a centrifugal barrel is rotatably connected between the slide bars on the left side and the right side, clamp grooves are symmetrically arranged on the left side and the right side of the bottom wall of the centrifugal barrel, the lower end of the hook claw extends into the clamp grooves, a centrifugal cavity with an upward opening is arranged in the centrifugal barrel, a filter screen is fixedly connected in the centrifugal cavity, a movable tube penetrating through the centrifugal barrel is slidably arranged on the bottom wall of the centrifugal cavity, a support plate is fixedly connected outside the centrifugal barrel through a spring, the support plate is connected with the bottom wall of the centrifugal barrel through a spring, fixed rods are respectively and fixedly arranged on the left side and the right side of the front wall and the rear wall of the centrifugal cavity, slide plates are slidably matched in the left side and the right side of the centrifugal cavity, the slide plates seal the movable tubes, the upper side of the sliding plate is rotatably connected with a swing rod, the upper side of the swing rod supports the filter screen, the swing rod is provided with a guide slot which is penetrated through from front to back, the fixed rod penetrates and is in sliding fit with the guide slot, the top wall of the centrifugal barrel is rotatably connected with a cover plate outside the machine body, the upper side of the cover plate is slidably connected with a storage barrel, a storage cavity is arranged in the storage barrel, the lower side of the storage cavity is communicated with a discharge port which penetrates through the storage barrel, the cover plate is provided with a connecting port which penetrates through the cover plate at the lower side of the discharge port, sliding grooves are symmetrically arranged in the left side wall and the right side wall of the connecting port, a partition plate is slidably arranged on the wall body between the sliding grooves and the connecting port, the partition plate is connected with the inner wall of the sliding groove through a spring, the top wall of the sliding groove is slidably arranged with an L-shaped inclined plane rod which extends out of the cover plate to be in contact with the storage barrel, and the L-shaped inclined plane rod is in contact with the partition plate in the sliding groove, the front side wall and the rear side wall of the conical working cavity are symmetrically provided with rolling grooves with openings facing the centrifugal barrel, the lower side of the conical working cavity is provided with a belt cavity, a wall body between the rolling grooves and the belt cavity on the front side and the rear side is rotatably provided with a roller shaft, the roller shaft is fixedly connected with a roller in the rolling groove, the roller is in rolling connection with the centrifugal barrel, and the roller shaft on the front side and the rear side is in transmission connection with the belt cavity through a power belt; the wall body between toper working chamber and the belt chamber is equipped with the transmission chamber, slidable mounting has the collection pipe support on the toper working chamber front and back wall, divide equally on the collection pipe support and be equipped with the ascending collection chamber of opening, transmission chamber with wall body between the toper working chamber rotates installs transmission shaft and pivot, the pivot is located collection pipe support left side, the transmission shaft is located collection pipe support right side, the transmission shaft with the pivot is in the transmission chamber is connected through connecting the belt transmission, the pivot is in toper working chamber fixedly connected with impels curved gear and L shape pole, impel curved gear and the meshing connection of collection pipe support, L shape pole and the backup pad contact, the transmission shaft in toper working chamber splined connection has the spline sleeve, fixedly connected with conical surface gyro wheel on the spline sleeve outer wall, the spline sleeve is rotatably connected with a supporting push plate on the upper side of the conical roller, the supporting push plate is in contact with the supporting plate, and the supporting plate is connected with the bottom wall of the conical working cavity through a spring; the collecting pipe frame is provided with a containing groove with a right opening on the right side of the collecting cavity, a push rod is arranged in the containing groove in a sliding mode, the push rod is connected with the conical surface idler wheel, a connecting sliding groove with a forward opening is formed in the rear side wall of the collecting cavity, a connecting sliding block is arranged in the connecting sliding groove in a sliding mode, the front side of the connecting sliding block is connected with a connecting rotating shaft extending into the collecting cavity through a torsional ring in a rotating mode, an overturning cover plate is fixedly connected into the collecting cavity through the connecting rotating shaft, a connecting rope is fixedly connected to the right side of the connecting sliding block, the connecting rope is in sliding fit with the right side wall of the collecting pipe frame and extends out of the collecting pipe frame, and the right side of the connecting rope extends into the containing groove to be fixedly connected with the left end of the push rod; a motor cavity is arranged on a wall body between the rolling groove at the rear side and the belt cavity, the roller shaft at the rear side is rotatably connected with the motor cavity and a wall body between the rolling groove at the rear side and the belt cavity at the rear side, a motor is fixedly arranged on the rear side wall of the motor cavity, the front side of the motor is in power connection with a worm motor shaft, the worm motor shaft and the roller shaft are connected through a linking bevel gear set, a transmission worm is rotatably arranged on the wall body between the motor cavity and the conical working cavity, the transmission worm is in transmission connection with the motor cavity and the worm motor shaft through a linking belt, a linking worm wheel is fixedly connected in the transmission cavity of the transmission shaft, the transmission worm is in meshing connection with the transmission cavity and the linking worm wheel, a T-shaped rod is slidably arranged on the wall body between the transmission cavity and the conical working cavity, and supporting rotating plates are rotatably arranged on the top wall of the transmission cavity and the front and rear sides of the T-shaped rod, the supporting rotating plates on the front side and the rear side are connected through springs, and the supporting rotating plates are in contact with the connecting belts; the lifting cavity is symmetrically arranged on the left side wall and the right side wall of the conical working cavity, the left side wall and the right side wall of the conical working cavity are rotatably provided with a connecting shaft, the connecting shaft is fixedly connected with a driven worm gear in the motor cavity, the driven worm gear is meshed with the worm motor shaft, the connecting shaft is fixedly connected with an upgrading arc gear in the lifting cavity, the top wall of the lifting cavity is slidably provided with a lifting rack extending out of the machine body, the lifting rack is connected with the bottom wall of the lifting cavity through a spring, the lifting rack is meshed with the upgrading arc gear, the cover plate is provided with a transition groove with a downward opening on the side of the chute far away from the connecting port, the left side wall and the right side wall of the transition groove are rotatably provided with connecting shafts, the connecting shafts are fixedly connected with driven wheels and chain wheels, the chain wheels are wound with pull ropes, and the pull ropes are in sliding fit with the wall bodies between the transition groove and the chute, the pull rope is fixedly connected with the partition board in the sliding groove, and the lifting rack is meshed with the driven wheel; the toper working chamber with slide bar sliding fit department is equipped with the opening orientation the spacing groove of centrifugation bucket, the slide bar in spacing inslot fixedly connected with fixed block, the fixed block passes through spring coupling the spacing groove diapire, be equipped with the annular on the centrifugation bucket outer wall, control the side the slide bar in fixedly connected with fixture block in the apron.