CN112156747B

CN112156747B - Reaction cup and reaction cup mixing device

Info

Publication number: CN112156747B
Application number: CN202011175328.9A
Authority: CN
Inventors: 华斌; 王宇; 黄一鸣; 官志超
Original assignee: Suzhou Yuce Biotechnology Co ltd
Current assignee: Suzhou Yuce Biotechnology Co ltd
Priority date: 2020-10-28
Filing date: 2020-10-28
Publication date: 2024-04-30
Anticipated expiration: 2040-10-28
Also published as: CN112156747A

Abstract

The application discloses a reaction cup and a reaction cup mixing device, and relates to the technical field of mixing equipment. The reaction cup mixing device comprises a frame, a rotary disk, a first rotary mechanism, a mixing assembly and a reaction chamber, wherein a plurality of mounting grooves for mounting reaction cups are formed in the rotary disk; the first rotating mechanism is arranged on the frame, is in transmission connection with the rotating disc and is used for driving the rotating disc to rotate; the reaction chamber is arranged on the frame, the rotating disk is arranged in the reaction chamber, and a third perforation is arranged on the reaction chamber; the mixing component comprises a second rotating mechanism and a friction wheel, wherein the second rotating mechanism is arranged on the frame, is in transmission connection with the friction wheel and is used for driving the friction wheel to rotate, the friction wheel and the rotating disk are arranged at intervals, and the friction wheel is provided with an overlapping part; the second rotating mechanism is arranged on the outer side of the reaction chamber, and the overlapping part passes through the third perforation and then overlaps with the rotating disk along the radial direction so as to vibrate the reaction cup. The application can improve the mixing effect and can lead the mixing effect to be more uniform.

Description

Reaction cup and reaction cup mixing device

Technical Field

The application relates to the technical field of mixing equipment, in particular to a reaction cup and a mixing device of the reaction cup.

Background

In the prior art, a fluorescent dye is a nano material with special optical properties, and when the fluorescent dye is at rest for more than 24 hours, partial sedimentation can occur, so that the solution is uneven, and the solution is required to be uniformly mixed so as to ensure the uniformity of the solution.

Disclosure of Invention

The application aims to provide a reaction cup and a reaction cup mixing device, which can ensure that the mixing effect is more uniform.

Embodiments of the present application are implemented as follows:

In a first aspect, an embodiment of the present invention provides a reaction cup, where at least one friction member is disposed on an inner surface of the reaction cup.

In an embodiment, a fourth flange is disposed on an outer surface of the reaction cup, and when the reaction cup is disposed in the mounting groove, the fourth flange is used to abut against the rotating disk, so as to limit the up-and-down movement of the reaction cup.

In a second aspect, an embodiment of the present invention provides a reaction cup mixing device, where the reaction cup mixing device includes a frame, a rotating disc, a first rotating mechanism, a mixing assembly and a reaction chamber, and the rotating disc is provided with a plurality of mounting slots for mounting reaction cups; the first rotating mechanism is arranged on the frame, is in transmission connection with the rotating disc and is used for driving the rotating disc to rotate; the reaction chamber is arranged on the frame, the rotating disk is arranged in the reaction chamber, and a third perforation is arranged on the reaction chamber; the mixing component comprises a second rotating mechanism and a friction wheel, wherein the second rotating mechanism is arranged on the frame, is in transmission connection with the friction wheel and is used for driving the friction wheel to rotate, the friction wheel and the rotating disk are arranged at intervals, and the friction wheel is provided with an overlapping part; the second rotating mechanism is arranged on the outer side of the reaction chamber, and the overlapping part passes through the third perforation and then overlaps with the rotating disk along the radial direction so as to vibrate the reaction cup.

In an embodiment, the reaction cup mixing device further comprises: at least one reaction cup, at least one friction piece is arranged on the inner surface of the reaction cup.

In an embodiment, the reaction cup mixing device further comprises: the counting assembly comprises a code disc and a counting optical coupler, the counting optical coupler is arranged on the frame, and the code disc is in transmission connection with the rotating disc.

In an embodiment, the counting assembly further includes a third supporting frame, and the counting optocoupler is fixed on the bottom plate through the third supporting frame.

In an embodiment, the reaction cup mixing device further comprises: the zero-position assembly comprises a zero-position baffle and a zero-position optical coupler, the zero-position optical coupler is arranged on the frame, and the zero-position baffle is arranged on the code disc.

In an embodiment, the zero-position assembly further includes a fourth supporting frame, and the zero-position optocoupler is fixed on the bottom plate through the fourth supporting frame.

In one embodiment, the reaction chamber comprises a pot body and a heating film, wherein the pot body is arranged on the rack, and a first groove is formed in the bottom of the pot body; the heating film is arranged in the first groove; wherein, the third perforation includes the first opening of locating the pan body lateral wall.

In one embodiment, the reaction chamber further comprises: the cover plate is covered on the pot body and is provided with a hole for adding a sample, a hole for adding a reagent and a hole for detecting.

In one embodiment, the cover plate is provided with a hole for judging the cup, and the pot body is provided with a cup judging sensor.

In one embodiment, the reaction chamber further comprises: the heat insulation base plate is clamped between the heating film and the frame.

In one embodiment, the reaction chamber further comprises: the outer sleeve is covered outside the pot body, the heat insulation base plate and the cover plate; wherein the third perforation further comprises a second opening arranged on the side wall of the outer sleeve.

In an embodiment, the first rotating mechanism comprises a central shaft, a transmission mechanism, a first rotating driving piece and a first supporting frame, and the first supporting frame is respectively connected with the first rotating driving piece and the frame; the first rotary driving piece is in transmission connection with the central shaft through a transmission mechanism; the central shaft passes through the first perforation and the second perforation and then is connected with the rotary disk.

In an embodiment, the frame includes a bottom plate, a first through hole is formed in the bottom plate, a second through hole is formed in the reaction chamber, and the first rotary driving member, the first supporting frame and the first rotary driving member are all arranged on the outer side of the reaction chamber and are all arranged on the other side of the bottom plate opposite to the rotary disk.

In one embodiment, the second perforation includes a first hole provided in the pan body, a second hole provided in the heat insulating pad, a third hole provided in the jacket, and a fourth hole provided in the heating film.

In one embodiment, the transmission mechanism comprises a synchronous belt, a driving wheel and a driven wheel, wherein the driving wheel is connected with the first rotary driving piece, and the driven wheel is connected with the central shaft.

In one embodiment, the rotating disc comprises a rotating ring and a first adapter which are connected with each other, and the mounting groove is arranged on the rotating ring; the central shaft is connected with the rotating ring through a first adapter.

In one embodiment, the driven wheel has a central mounting hole in which a second adapter is disposed; the central shaft is connected with the driven wheel through a second adapter.

In an embodiment, a first mounting hole is formed in the first adapter, and a second mounting hole is formed in the second adapter, wherein one end of the central shaft is arranged in the first mounting hole in a penetrating manner, and the other end of the central shaft is arranged in the second mounting hole in a penetrating manner.

In one embodiment, the second rotation mechanism includes a second rotation driving member, a second supporting frame, a shaft sleeve and a pressing piece, wherein the second rotation driving member has a second main shaft; the second support frame is respectively connected with the second rotary driving piece and the frame; the shaft sleeve is sleeved on the second main shaft, a third flange is arranged on the shaft sleeve, the friction wheel is sleeved on the shaft sleeve and props against the third flange, and the pressing sheet is arranged on the other side of the friction wheel relative to the third flange.

In one embodiment, the base plate is provided with a plurality of support legs, and the support legs are provided with four support legs.

In one embodiment, the central shaft is sleeved with at least one bearing, the inner bottom surface of the pot body is provided with a first convex ring, and the inner surface of the first convex ring is provided with at least one mounting groove for mounting the bearing.

In an embodiment, a second convex ring is arranged on the inner bottom surface of the pot body, and the second convex ring and the first convex ring are coaxially arranged.

In one embodiment, the bearings are arranged at two ends of the first convex ring, and the mounting grooves are arranged at two ends of the first convex ring.

In an embodiment, the central shaft is sleeved with a bearing pressing ring, and the bearing pressing ring is used for propping against a bearing arranged below and limiting the axial movement of the bearing.

In one embodiment, the end of the central shaft is provided with a first flange, the longitudinal sections of the first flange and the central shaft are in a cross shape, and the longitudinal section of the first mounting hole is in a cross shape and is matched with the first flange and the central shaft.

In an embodiment, a second flange is disposed on an end of the central shaft, the second flange is disposed on a lower surface of the first flange, and the second flange is used for abutting against a bearing disposed above the second flange and limiting axial movement of the bearing.

In one embodiment, four lightening holes are provided on the friction wheel.

Compared with the prior art, the application has the beneficial effects that:

According to the application, the friction piece is arranged in the reaction cup, when the friction wheel enables the reaction cup to vibrate, the friction piece in the reaction cup can be rubbed with liquid such as fluorescent material in the reaction cup, so that the mixing effect can be improved, and the mixing effect can be more uniform.

When the friction wheel does not work, in the periodic rotation working process of the rotating disk, when the reaction cup on the rotating disk passes through the mixing position, the outer surface of the reaction cup is in contact with the friction wheel, the reaction cup can be rotated by the contact force between the reaction cup and the friction wheel, the rotation of the reaction cup can enable the friction piece in the reaction cup and the liquid in the reaction cup to generate oscillation force, so that the liquid in the reaction cup is fully and uniformly mixed, and the antigen-antibody combination reaction in the liquid in the reaction cup is more complete.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

Fig. 1 is a schematic structural view of a reaction cup according to an embodiment of the present application.

Fig. 2 is a cross-sectional view of fig. 1 in A-A direction according to an embodiment of the present application.

Fig. 3 is a schematic structural view of a mixing device for a reaction cup according to an embodiment of the present application.

Fig. 4 is an exploded view of a mixing device for a cuvette according to an embodiment of the present application.

Fig. 5 is a schematic structural view of a mixing device for a reaction cup according to an embodiment of the present application.

Fig. 6 is an exploded view of a mixing device for a cuvette according to an embodiment of the present application.

Fig. 7 is an exploded view of a cuvette mixing device according to an embodiment of the present application.

Fig. 8 is an exploded cross-sectional view showing a part of the structure of a cuvette mixing apparatus according to an embodiment of the present application.

Fig. 9 is a plan view of a cuvette mixing apparatus according to an embodiment of the present application.

Fig. 10 is a B-B directional cross-sectional view of fig. 9, illustrating an embodiment of the present application.

Fig. 11 is a front view of a mixing assembly according to an embodiment of the application.

Fig. 12 is a top view of a mixing assembly according to an embodiment of the application.

Fig. 13 is a top view of a mixing assembly according to an embodiment of the application.

Icon: 1-a reaction cup; 1 a-the inner surface of the reaction cup; 1 b-the outer surface of the reaction cup; 11-friction member; 12-fourth flange; 13-graining; 2-a reaction cup mixing device; 300-frame; 310-a bottom plate; 311-first perforation; 320-feet; 400-rotating disc; 410-a rotating ring; 411-mounting slots; 420-a first adapter; 421-first mounting hole; 500-a first rotation mechanism; 510-a central axis; 511-bearings; 512-bearing press ring; 513-a first flange; 514-a second flange; 520-a transmission mechanism; 521-synchronous belt; 522-a driving wheel; 523-driven wheel; 524-a central mounting hole; 525-a second adapter; 526-a second mounting hole; 530-a first rotary drive; 531-first spindle; 540-a first support frame; 600-uniformly mixing the components; 610-friction wheel; 611-overlapping portions; 612-lightening holes; 613-teeth; 620-a second rotation mechanism; 621-a second rotary drive; 622-second spindle; 623-a second support frame; 624-sleeve; 625-a third flange; 626-tabletting; 700-counting component; 710-code wheel; 711-notch; 720-counting optocouplers; 730-a third support frame; 800-zero assembly; 810-zero position stop piece; 820-zero optocoupler; 830-fourth support; 900-reaction chamber; 920-pot body; 920 a-inner bottom surface of the pan body; 920 b-the outer bottom of the pan body; 920 c-side walls of the pan body; 921-first grooves; 923-a first collar; 924-mounting grooves; 925-a second convex ring; 930-heating the film; 940-cover plate; 941-a well for sample addition; 942-wells for adding reagents; 943-detection well; 944-hole for judging cup; 950-cup judging sensor; 960-heat insulation backing plate; 970-outer sleeve; 981-first hole; 982-second well; 983-third well; 984-fourth well; 990-third perforations; 991-a first opening; 992-second opening.

Detailed Description

The terms "first," "second," "third," and the like are used merely for distinguishing between descriptions and not for indicating a sequence number, nor are they to be construed as indicating or implying relative importance.

Furthermore, the terms "horizontal," "vertical," "overhang," and the like do not denote a requirement that the component be absolutely horizontal or overhang, but rather may be slightly inclined. As "horizontal" merely means that its direction is more horizontal than "vertical", and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.

In the description of the present application, it should be noted that, directions or positional relationships indicated by terms such as "inner", "outer", "left", "right", "upper", "lower", etc., are based on directions or positional relationships shown in the drawings, or directions or positional relationships conventionally put in use of the product of the application, are merely for convenience of describing the present application and simplifying the description, and are not indicative or implying that the apparatus or element to be referred to must have a specific direction, be configured and operated in a specific direction, and thus should not be construed as limiting the present application.

In the description of the present application, unless explicitly stated and limited otherwise, the terms "disposed," "mounted," "connected," and "coupled" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements.

The technical solutions of the present application will be clearly and completely described below with reference to the accompanying drawings.

Referring to fig. 1, a schematic structure of a reaction cup 1 according to an embodiment of the application is shown. Referring to FIG. 2, a cross-sectional view of the direction A-A of FIG. 1 is shown according to an embodiment of the present application. The reaction cup 1 can be applied to equipment such as an incubation reaction cup mixing device 2, a chemiluminescent immunity detection instrument and the like and is used for containing liquids such as fluorescent materials and the like. At least one friction member 11 is provided on the inner surface 1a of the reaction cup. The friction piece 11 is arranged at the bottom of the reaction cup 1. The cross section of the reaction cup 1 may be circular, square or other shapes, and the cylindrical friction member 11 may be strip-shaped, dot-shaped or other shapes, and in this embodiment, the friction member 11 is provided with four elongated ribs, and the four friction members 11 are distributed in a circumferential array around the axis of the reaction cup 1. The upper half part of the reaction cup 1 is cylindrical, the lower half part is conical-like, and the inner bottom surface of the reaction cup 1 is arc-shaped.

In this embodiment, by arranging the friction member 11 in the reaction cup 1, when the reaction cup 1 vibrates, the friction member 11 in the reaction cup 1 can "rub" with liquid such as fluorescent material in the reaction cup 1, so as to improve the mixing effect, and make the mixing effect more uniform, so that the liquid in the reaction cup 1 fully reacts, and the detection effect is improved.

The outer surface 1b of the cuvette is provided with a fourth flange 12, which fourth flange 12 is used for extracting the cuvette 1 or limiting the up-and-down movement of the cuvette 1.

The outer surface 1b of the reaction cup is provided with a plurality of granular frosted surfaces 13, so that the outer surface 1b of the reaction cup is a granular frosted surface, friction force is increased during mixing, and the contact friction force between the reaction cup 1 and the friction wheel 610 is increased, so that the effect of more fully mixing is achieved. In this embodiment, the plurality of granular sand stones 13 are all disposed above the fourth flange 12.

Fig. 3 is a schematic structural diagram of a mixing device 2 for a reaction cup according to an embodiment of the application. The cuvette mixing device 2 comprises a frame 300, and a mixing component 600 and a reaction chamber 900 are arranged on the frame 300. The mixing assembly 600 is provided with one side of the reaction chamber 900.

Fig. 4 is an exploded view of a cuvette mixing device 2 according to an embodiment of the application. A rotating disk 400 is provided in the reaction chamber 900, and a plurality of mounting slots 411 for mounting the reaction cups 1 are provided in the rotating disk 400. In the present embodiment, 16 mounting slots 411 are provided.

The cuvette mixing apparatus 2 further includes at least one cuvette 1, and when the cuvette 1 is disposed in the mounting groove 411, the fourth flange 12 is used to abut against the rotating disc 400, so that the up-and-down movement of the cuvette 1 can be restricted.

The frame 300 is provided with a first rotating mechanism 500, and the first rotating mechanism 500 is in transmission connection with the rotating disc 400 and is used for driving the rotating disc 400 to rotate.

The mixing assembly 600 includes a second rotating mechanism 620 and a friction wheel 610, where the second rotating mechanism 620 is disposed on the frame 300 and is in transmission connection with the friction wheel 610, and is used for driving the friction wheel 610 to rotate, the friction wheel 610 and the rotating disk 400 are disposed at intervals, and the friction wheel 610 has an overlapping portion 611;

the reaction chamber 900 is provided with a third through hole 990, the second rotating mechanism 620 is disposed at the outer side of the reaction chamber 900, and the overlapping portion 611 overlaps the rotating disk 400 along the radial direction after passing through the third through hole 990, i.e. the overlapping portion 611 is disposed directly above the rotating disk 400, for vibrating the reaction cup 1.

The chassis 300 includes a base plate 310 and four legs 320 provided on the base plate 310. The base plate 310 and the support legs 320 may be integral or detachably connected.

The reaction chamber 900 includes a pot 920, a cover 940 and an outer jacket 970, wherein the pot 920 is disposed on the bottom plate 310 of the frame 300, the cover 940 is disposed on the pot 920, and the outer jacket 970 is disposed outside the pot 920 and the cover 940. The cross-section of the reaction chamber 900 and the rotating disk 400 may be square, circular, or other shapes.

In another embodiment, the friction member 11 may not be disposed in the reaction cup 1. In this embodiment, the friction wheel 610 rotates to mix the reaction, and the reaction cup 1 of this embodiment may be an immunization reaction cup 1, which can be used for detection, and the friction member 11 is not provided, so that the inner wall is smooth.

In one embodiment, the friction member 11 may be disposed in the reaction cup 1. In this embodiment, besides rotating the friction wheel 610 to mix the liquid in the reaction cup 1, when the friction wheel 610 does not work, the first rotating mechanism 500 drives the rotating disc 400 to periodically rotate, the rotating disc 400 drives the reaction cup 1 disposed in the mounting slot 411 to rotate, the reaction cup 1 rotates to the mixing assembly 600 (i.e. rotates to the mixing position), the overlapping portion 611 of the friction wheel 610 contacts with the reaction cup 1, so that the reaction cup 1 vibrates, and the contact force between the reaction cup 1 and the friction wheel 610 also causes the reaction cup 1 to rotate, and the rotation of the reaction cup 1 causes the friction piece 11 in the reaction cup 1 and the liquid in the reaction cup 1 to generate an oscillating force, so that the liquid in the reaction cup 1 is sufficiently mixed, and the antigen-antibody binding reaction in the liquid in the reaction cup 1 is more sufficient. And the mixing effect is better in the embodiment compared with the embodiment without the friction member 11.

Fig. 5 is a schematic structural diagram of a mixing device 2 for a reaction cup according to an embodiment of the application. The reaction cup mixing device 2 further comprises a counting assembly 700, the counting assembly 700 comprises a code disc 710 and a counting optical coupler 720, the counting optical coupler 720 is arranged on the frame 300, and the code disc 710 is in transmission connection with the rotary disc 400. The code wheel 710 is provided with a plurality of notches 711 corresponding to the mounting slots 411, and when the rotary disk 400 rotates, the code wheel 710 rotates synchronously, and the counting optocoupler 720 can be used for detecting the number of the rotated mounting slots 411, i.e. the reaction cups 1.

The reaction cup mixing device 2 further includes: the zero assembly 800, the zero assembly 800 includes a zero stop 810 and a zero optocoupler 820, the zero optocoupler 820 is disposed on the frame 300, and the zero stop 810 is disposed on the code wheel 710. When the code wheel 710 rotates, the zero position blocking piece 810 rotates synchronously, so that the zero position blocking piece 810 can be set to be zero position, and when the zero position blocking piece 810 reaches the zero position optocoupler 820 for the second time, the code wheel 710, namely the rotary disk 400 rotates for one circle, so that the zero position assembly 800 can be used for detecting the number of circles of the rotary disk 400.

Fig. 6 is an exploded view of a cuvette mixing device 2 according to an embodiment of the application. The third perforation 990 includes a first opening 991 provided in a side wall 920c of the pan body and a second opening 992 provided in a side wall of the outer jacket 970.

The reaction chamber 900 includes a heating film 930 and a heat insulation backing plate 960, and the reaction chamber 900 includes a cover plate 940, a pot 920, the heating film 930 and the heat insulation backing plate 960 sequentially disposed from top to bottom, the heat insulation backing plate 960 being disposed on the bottom plate 310. In this embodiment, the heat-insulating base plate 960 is fixed to the bottom plate 310 by bolting, etc., and the pan body 920 is fixed to the heat-insulating base plate 960 and the cover plate 940 by bolting, etc., so that the heating film 930 is sandwiched between the pan body 920 and the heat-insulating base plate 960. The outer sleeve 970 is in a round tube shape and covers the pot 920, the heat insulation backing plate 960 and the cover plate 940.

In an operation process, the heating film 930 can heat the interior of the reaction chamber 900, and the temperature in the reaction chamber 900 is increased to facilitate the sufficient reaction of the liquid such as fluorescent material in the reaction cup 1. While the insulating spacer 960 may be made of an insulating material to insulate the temperature transfer between the racks 300 and the reaction chamber 900 to prevent the racks 300 from being too hot.

The bottom plate 310 is provided with a first perforation 311, the reaction chamber 900 is provided with a second perforation, and the second perforation comprises a first hole 981 which is arranged on the pot 920, a second hole 982 which is arranged on the heat insulation backing plate 960, a third hole 983 which is arranged on the outer sleeve 970 and a fourth hole 984 which is arranged on the heating film 930, which are communicated with each other.

The first rotation mechanism 500 includes a central shaft 510, a transmission mechanism 520, a first rotation driving member 530 and a first supporting frame 540, and the first supporting frame 540 is connected to the first rotation driving member 530 and the frame 300 by bolting or the like; the first rotary driving member 530 is in transmission connection with the central shaft 510 via a transmission mechanism 520, and the first rotary driving member 530 may be a driving member such as a rotary motor, and has a first main shaft 531; the central shaft 510 passes through the first perforation 311 and the second perforation and then is connected with the rotary disk 400.

The first rotation driving member 530, the first supporting frame 540 and the first rotation driving member 530 are all disposed outside the reaction chamber 900, and are all disposed at the other side of the bottom plate 310 with respect to the rotating plate 400. In the present embodiment, the rotating disc 400 is disposed above the base plate 310, and the first rotating driving member 530, the first supporting frame 540 and the first rotating driving member 530 are disposed below the base plate 310.

The transmission 520 may be a gear, belt, or other transmission. In this embodiment, the transmission mechanism 520 includes a timing belt 521, a driving pulley 522, and a driven pulley 523, the driving pulley 522 is connected to the first main shaft 531 of the first rotary driving member 530, and the driven pulley 523 is connected to the central shaft 510.

Fig. 7 is an exploded view of a cuvette mixing device 2 according to an embodiment of the application. The second rotation mechanism 620 includes a second rotation driving unit 621, a second support frame 623, a shaft sleeve 624, and a pressing piece 626, and the second rotation driving unit 621 may be a driving unit such as a rotary motor; having a second spindle 622; the second support frame 623 is connected to the second rotary driving unit 621 and the frame 300, respectively; the shaft sleeve 624 is sleeved on the second main shaft 622, a third flange 625 is arranged on the shaft sleeve 624, the friction wheel 610 is sleeved on the shaft sleeve 624 and abuts against the third flange 625, and the pressing sheet 626 is arranged on the other side of the friction wheel 610 relative to the third flange 625.

The rotary disk 400 includes a rotary ring 410 and a first adapter 420 connected to each other, the rotary ring 410 is sleeved on the first adapter 420 and can rotate along with the rotation of the first adapter 420, and the mounting slot 411 is arranged on the rotary ring 410; the central shaft 510 is connected to the rotary ring 410 through the first adapter 420.

The driven wheel 523 has a central mounting hole 524, and a second adapter 525 is arranged in the central mounting hole 524; the central shaft 510 is connected to the driven wheel 523 via a second adapter 525.

The counting assembly 700 further includes a third support frame 730, the counting optocoupler 720 is fixed on the bottom plate 310 through the third support frame 730, and the third support frame 730 can be fixed by a bolt connection or the like.

The zero subassembly 800 further includes a fourth support 830, the zero optocoupler 820 is fixed on the base plate 310 by the fourth support 830, and the fourth support 830 can be fixed by bolting or the like.

Referring to fig. 8, an exploded cross-sectional view of a part of the structure of a cuvette mixing apparatus 2 according to an embodiment of the application is shown. The outer bottom 920b of the pot body is provided with a first groove 921; the heating film 930 is disposed within the first recess 921.

The first adaptor 420 is provided with a first mounting hole 421, and the second adaptor 525 is provided with a second mounting hole 526, wherein one end of the central shaft 510 is arranged in the first mounting hole 421 in a penetrating manner, and the other end is arranged in the second mounting hole 526 in a penetrating manner.

The central shaft 510 is sleeved with at least one bearing 511, the inner bottom surface 920a of the pot body is provided with a first convex ring 923, and the inner surface of the first convex ring 923 is provided with at least one mounting groove 924 for mounting the bearing 511. The central shaft 510 is sleeved with a bearing pressing ring 512, and the bearing pressing ring 512 is used for abutting against a bearing 511 arranged below and limiting the axial movement of the bearing 511. In this embodiment, the bearings 511 are provided in two, and the mounting grooves 924 are provided in two and are respectively provided at both ends of the first collar 923. The bearing 511 may be a rolling bearing 511 or a sliding bearing 511, so that the friction coefficient during the movement of the central shaft 510 may be reduced.

The end of the central shaft 510 is provided with a first flange 513, the longitudinal section of the first flange 513 and the central shaft 510 is in a cross shape, and the longitudinal section of the first mounting hole 421 is in a cross shape and is matched with the first flange 513 and the central shaft 510.

The end of the central shaft 510 is provided with a second flange 514, the second flange 514 is provided on the lower surface of the first flange 513, and the second flange 514 is configured to abut against the bearing 511 provided above and to limit the axial movement of the bearing 511.

The inner bottom 920a of the pot body is provided with a second convex ring 925, and the second convex ring 925 and the first convex ring 923 are coaxially arranged. The height of the second convex ring 925 is smaller than that of the first convex ring 923, so that the second convex ring 925 is not in contact with the rotating disk 400, and the second convex ring 925 is prevented from interfering with the rotation of the rotating disk 400.

Referring to fig. 9, a top view of a cuvette mixing apparatus 2 according to an embodiment of the application is shown. The cover sheet 940 is provided with a sample addition hole 941, a reagent addition hole 942, and a detection hole 943 spaced apart from each other. Wherein the reagent application aperture 942 is used to apply reagent closest to the mixing assembly 600 and the overlapping portion 611 of the friction wheel 610 is visible in the reagent application aperture 942. The detection hole 943 is adjacent to the reagent-adding hole 942, and can be used in combination with other detection means for detection. The well 941 for sample addition is adjacent to the well 942 for reagent addition and is farther than the well 943 for detection.

The cover plate 940 is provided with a hole 944 for judging a cup, and the hole 944 for judging a cup is opposite to the hole 942 for adding a reagent and is located on a diameter of the cover plate 940. The pot 920 is provided with a cup determining sensor 950, and the cup determining sensor 950 is configured to detect whether or not the reaction cup 1 is present in the mounting slot 411 facing the cup determining hole 944.

Referring to fig. 10, a cross-sectional view of fig. 9 in the B-B direction is shown according to an embodiment of the application. The central shaft 510, the bearing 511, the pot 920, the cover 940, the rotating ring 410, the first adapter 420 and the second adapter 525 are all coaxially arranged. The first adapter 420 is coupled to the central shaft 510 by a bolt, pin, or other fastener. The code wheel 710 is fixedly provided on the driven wheel 523 by means of bolting or the like.

Referring to fig. 11, a front view of a mixing assembly 600 according to an embodiment of the application is shown. The pressing piece 626 is disposed above the friction wheel 610, and the third flange 625 of the boss 624 is disposed below the friction wheel 610. Both the tab 626 and the boss 624 may limit the up and down movement of the friction wheel 610.

Referring to fig. 12, a top view of a mixing assembly 600 according to an embodiment of the application is shown. The friction wheel 610 is provided with four evenly distributed lightening holes 612. The weight reducing holes 612 can reduce the weight of the friction wheel 610, and the friction wheel 610 can be made of rubber or other elastic material, so that the leakage caused by overlarge vibration of the friction wheel 610 to the reaction cup 1 can be avoided, and the friction wheel 610 has certain elasticity, can be well in full contact with the outer wall of the reaction cup 1, and improves the mixing effect.

Referring to fig. 13, a top view of a mixing assembly 600 according to an embodiment of the application is shown. The convex teeth 613 are arranged on the outer surface of the friction wheel 610, so that the friction wheel 610 forms a gear-shaped structure, friction force with the reaction cup 1 can be increased, and a good mixing effect is achieved.

It should be noted that the features of the embodiments of the present application may be combined with each other without conflict.

The above is only a preferred embodiment of the present application, and is not intended to limit the present application, but various modifications and variations can be made to the present application by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the protection scope of the present application.

Claims

1. A reaction cup blending device, comprising:

A frame;

the rotating disk is provided with a plurality of mounting grooves for mounting the reaction cups;

the first rotating mechanism is arranged on the frame, is in transmission connection with the rotating disc and is used for driving the rotating disc to rotate;

The reaction chamber is arranged on the rack, the rotating disc is arranged in the reaction chamber, and a third perforation is arranged on the reaction chamber; and

The mixing assembly consists of a second rotating mechanism and a friction wheel, wherein the second rotating mechanism is arranged on the frame, is in transmission connection with the friction wheel and is used for driving the friction wheel to rotate, the friction wheel and the rotating disk are arranged at intervals, and the friction wheel is provided with an overlapping part;

wherein the second rotating mechanism is arranged at the outer side of the reaction chamber, the overlapping part passes through the third perforation and then overlaps with the rotating disk along the radial direction,

The reaction chamber includes:

The pot body is arranged on the rack, and a first groove is formed in the bottom of the pot body; and

The heating film is arranged in the first groove;

Wherein the third perforation comprises a first opening arranged on the side wall of the pot body,

The reaction cup mixing device also comprises a reaction cup, wherein the inner surface of the reaction cup is provided with four friction pieces which are distributed in a circumferential array around the axis of the reaction cup,

The upper half part of the reaction cup is cylindrical, the lower half part is conical-like, the inner bottom surface is arc-shaped,

The friction piece is an elongated rib arranged on the inner surface of the lower half part of the reaction cup which is similar to the cone shape, and the rib extends from the junction of the cylindrical upper half part of the reaction cup and the lower half part which is similar to the cone shape to the inner bottom surface,

The outer surface of the reaction cup is provided with a fourth flange which is used for extracting the reaction cup or limiting the reaction cup from moving up and down;

The outer surface of the reaction cup is also provided with a plurality of granular frosted surfaces which are all arranged above the fourth flange.

2. The cuvette mixing device according to claim 1, wherein the cuvette mixing device further comprises:

The counting assembly comprises a code disc and a counting optical coupler, the counting optical coupler is arranged on the frame, and the code disc is in transmission connection with the rotating disc; and

The zero-position assembly comprises a zero-position blocking piece and a zero-position optical coupler, the zero-position optical coupler is arranged on the frame, and the zero-position blocking piece is arranged on the code disc.

3. The cuvette mixing device according to claim 1, wherein the reaction chamber further comprises:

a cover plate, which is covered on the pot body and is provided with a hole for adding sample, a hole for adding reagent, a hole for detecting and a hole for judging the cup,

Wherein, the pot body is provided with a cup judging sensor.

4. The cuvette mixing device according to claim 3, wherein the reaction chamber further comprises:

The heat insulation base plate is clamped between the heating film and the rack; and

The jacket is covered outside the pot body, the heat insulation base plate and the cover plate;

Wherein the third perforation further comprises a second opening arranged on the side wall of the outer sleeve.

5. The cuvette mixing device according to any one of claims 1 to 4, wherein the frame comprises a bottom plate, wherein the bottom plate is provided with a first perforation, wherein the reaction chamber is provided with a second perforation,

The first rotation mechanism includes:

the central shaft penetrates through the first perforation and the second perforation and then is connected with the rotary disk;

A transmission mechanism;

The first rotary driving piece is in transmission connection with the central shaft through the transmission mechanism; and

The first supporting frame is respectively connected with the first rotary driving piece and the frame;

The first rotary driving piece, the first supporting frame and the first rotary driving piece are arranged on the outer side of the reaction chamber and on the other side of the bottom plate relative to the rotary disc.

6. The cuvette mixing device according to claim 5, wherein the rotating disc comprises a rotating ring and a first adapter connected to each other, the mounting groove being provided on the rotating ring;

The transmission mechanism comprises a synchronous belt, a driving wheel and a driven wheel, the driving wheel is connected with the first rotary driving piece, the driven wheel is connected with the central shaft, the driven wheel is provided with a central mounting hole, and a second adapter piece is arranged in the central mounting hole;

One end of the central shaft is connected with the second adapter, and the other end of the central shaft is connected with the first adapter.

7. The cuvette mixing device according to claim 1, wherein the second rotation mechanism comprises:

a second rotary drive member having a second spindle;

The second supporting frame is respectively connected with the second rotary driving piece and the frame;

The shaft sleeve is sleeved on the second main shaft, a third flange is arranged on the shaft sleeve, and the friction wheel is sleeved on the shaft sleeve and abuts against the third flange; and

And the pressing piece is arranged on the other side of the friction wheel relative to the third flange.