CN112155685A

CN112155685A - Dilatation injection system for preventing and treating arterial stenosis

Info

Publication number: CN112155685A
Application number: CN202010989311.0A
Authority: CN
Inventors: 谭最
Original assignee: Wuhan Ai Lu Tong Medical Technology Co ltd
Current assignee: Wuhan Ai Lu Tong Medical Technology Co ltd
Priority date: 2020-09-18
Filing date: 2020-09-18
Publication date: 2021-01-01

Abstract

The invention relates to an expansion injection system for preventing and treating arterial stenosis, which comprises a catheter, wherein a guide wire channel and a water injection channel which extend along the long axis direction of the catheter are arranged in the catheter; the first balloon is wrapped at one end of the catheter, the inner cavity of the first balloon is communicated with the water injection channel, and both ends of the first balloon are of conical structures after water injection expansion; the catheter joint is connected to the other end of the catheter, and is provided with a water injection port and a medicine injection port, the water injection channel is communicated with the water injection channel, and the medicine injection port is connected with the puncture guide tube seat; the catheter joint or the catheter is provided with a guide wire port which is communicated with the guide wire channel; the puncture guide tube is arranged in the catheter, one end of the puncture guide tube penetrates through the catheter and is attached to the conical surface of the first balloon close to the first balloon along the long axis direction of the catheter, and the other end of the puncture guide tube extends to be connected with the puncture guide tube seat through the interior of the catheter; the needle tail of the puncture needle is connected with a needle tube which can enter from a puncture guide tube seat. The advantages are that: the stability of the puncture angle is guaranteed, and the balloon is effectively protected from being damaged.

Description

Dilatation injection system for preventing and treating arterial stenosis

Technical Field

The invention relates to the technical field of medical instruments, in particular to an expansion injection system for preventing and treating arterial stenosis.

Background

Peripheral arterial disease PAD is a disease in which peripheral atherosclerotic plaques are formed, which causes stenosis and occlusion of peripheral arteries, and further causes chronic ischemia of limbs. Is the important cause of death and disability in the current global disease spectrum, and the death rate is second to coronary heart disease and cerebral apoplexy in cardiovascular and cerebrovascular diseases.

The main methods of current intraluminal treatment techniques are balloon angioplasty and stent implantation. The long-term restenosis rate of the traditional balloon dilatation can reach 80 percent, and the implantation of the stent brings new problems of stent related complications (stent displacement, fracture, thrombus in the stent and the like) and stent restenosis and the like.

Drug-coated balloons (DCB) and drug-eluting stents (DES) have become new hot spots for peripheral vascular diseases in recent years, and the DCB and DES mainly adopt paclitaxel drugs, and the drug coating can inhibit intimal hyperplasia, smooth muscle hyperplasia, migration and the like of blood vessels so as to prevent restenosis. However, DCB and DES have some disadvantages, mainly lie in that the spraying medicine can only contact with the vascular intima in short time, the osmotic administration is easy to be washed by blood flow, the local medicine concentration is difficult to maintain, and the curative effect is influenced; secondly, the concentration of the medicine is increased and the side effect of the medicine is caused because the medicine is easy to elute.

At present, a patent US7559923 (domestic patent CN107360123A) at abroad describes a system for inhibiting vasculitis, which mainly solves the defect that drugs are easy to be washed by blood flow after the current drug coating balloon is placed, and the system consists of a balloon catheter part and a drug injection part, wherein the balloon part is mainly used for adapting to different blood vessel diameters, and a microneedle for injecting drugs is pushed into a vascular interlayer to mainly play a role in providing pressure. General angiostenosis firstly needs to be dilated by a balloon and then replaced by a balloon injection system in the prior art for injection, so as to achieve the purpose of treatment.

Further, described in CNB is an intraluminal injection catheter device comprising a hollow catheter body and an injection mechanism. The injection mechanism comprises a support component, an end head, a hollow pull tube and an injection needle, wherein the support component is radially expanded by the pulling back action of the hollow pull tube, and a guide hole of the injection needle is driven to provide guidance and support for the injection needle so as to realize the injection function, but the expansion of the support component in the patent technology cannot realize the expansion of the narrow part in the cavity; secondly, the device realizes the expansion and the repositioning of the supporting component through the pulling back action, and the pulling back action easily changes the position of the supporting component in the cavity, so that the positioning is inaccurate. The hand is not only unstable, but also the force is difficult to control, thereby causing the puncture angle to change.

Disclosure of Invention

The invention aims to solve the technical problem of providing an expansion injection system for preventing and treating arterial stenosis, and effectively overcomes the defects of the prior art.

The technical scheme for solving the technical problems is as follows:

a dilation injection system for preventing and treating arterial stenosis, comprising: the catheter is internally provided with a guide wire channel and a water injection channel which extend along the long axis direction of the catheter; the first balloon is wrapped at one end of the catheter, the inner cavity of the first balloon is communicated with the water injection channel, and both ends of the first balloon are in conical structures after water injection and expansion; a catheter joint which is connected with the other end of the catheter and is provided with a water injection port and a medicine injection port, wherein the water injection channel is communicated with the corresponding end of the water injection channel, and the medicine injection port is connected with a puncture guide tube seat; a guide wire port communicated with the guide wire channel is arranged on the catheter joint or at the other end of the catheter, and the guide wire port is communicated with the corresponding end of the guide wire channel; a puncture guide tube provided in the catheter, one end of which passes through one end of the catheter and is fixed to a tapered surface of the first balloon near the one end thereof in a manner of being bonded to the long axis direction of the catheter, and the other end of which extends through the inside of the catheter to be connected to the puncture guide tube base; the puncture needle can enter from the puncture guide tube seat and is pushed and pulled through the needle tube under the external force until the needle point is pushed out or retracted from one end of the puncture guide tube.

On the basis of the technical scheme, the invention can be further improved as follows.

Furthermore, one end of the puncture guide tube seat extends into the medicine injection port and is hermetically connected with the medicine injection port, a needle tube intervention cavity is arranged inside the other end of the puncture guide tube seat, and the other end of the puncture guide tube penetrates through one end of the puncture guide tube seat and is communicated with the needle tube intervention cavity.

The needle tube comprises a needle tube seat, a needle tube is arranged in the needle tube seat, a tube cavity is arranged in one end of the needle tube seat, a socket part matched with the needle tube insertion cavity is arranged at the other end of the needle tube seat, one end, far away from the puncture needle, of the needle tube penetrates into the socket part and extends to be communicated with one end, close to the tube cavity, of the tube cavity, the socket part is used for being inserted into the needle tube insertion cavity and slides along the needle tube insertion cavity under the action of external force, and therefore the needle tube is pushed and pulled so that the needle point of the puncture needle is pushed out or retracted from one.

Furthermore, the puncture guide tubes are provided with a plurality of puncture guide tubes, one ends of the puncture guide tubes penetrate through one end of the catheter respectively, the puncture guide tubes are uniformly attached and fixed on a conical surface along the axial direction of the conical structure at the corresponding end of the first balloon respectively, the corresponding puncture needles are provided with a plurality of puncture needles, the number of the puncture needles is consistent with that of the puncture guide tubes, the needle tail of each puncture needle is connected with the needle tube, and the puncture needles penetrate through the puncture guide tube seats respectively and enter the corresponding puncture guide tubes.

Further, the area of the surface of the catheter, which is positioned in the wrapping range of the first balloon, is provided with at least two radiopaque first developing mark rings along the long axis direction.

Further, the catheter joint is a four-way joint, one interface of the four-way joint is hermetically connected and communicated with the other end of the catheter, the other three interfaces respectively form the water injection port, the guide wire port and the medicine injection port, and the guide wire channel extends to be connected and communicated with the guide wire port; or the catheter joint is a three-way joint, one interface of the three-way joint is hermetically connected with the other end of the catheter 1 and is communicated with the other two interfaces to form the water injection port and the medicine injection port respectively, the other end of the catheter is provided with a guide wire fast exchange port communicated with the guide wire channel, and the guide wire fast exchange port forms the guide wire port.

Further, the catheter comprises an outer tube and an inner tube arranged in the outer tube, the other ends of the outer tube and the inner tube are connected with the catheter joint together, an inner cavity for the puncture guide tube to pass through is formed between the outer tube and the inner tube, one end of the inner tube extends out of one end of the outer tube, the first balloon is wrapped and arranged outside one end of the inner tube and is close to one end of the outer tube, and the inner tube is internally provided with the guide wire channel and the water injection channel along the long axis direction; one end of the puncture guide tube penetrates through the outer wall of one end of the outer tube and extends to be attached and fixed to the conical surface of one end, close to the outer wall, of the first balloon along the outer wall of one end of the outer tube, or one end of the puncture guide tube penetrates out of one end of the outer tube along the inner wall of the outer tube and extends to be attached and fixed to the conical surface of one end, close to the inner wall, of the first balloon.

The catheter further comprises a second balloon, the second balloon is wrapped at one end of the inner tube and is arranged at one end, far away from the catheter joint, of the first balloon at intervals, and one end of the second balloon extends to be connected and communicated with the other end of the first balloon.

Further, the area of the surface of the catheter, which is positioned in the wrapping range of the second balloon, is provided with at least two radiopaque second developing mark rings along the long axis direction.

The invention has the beneficial effects that: structural design is reasonable, has ensured the stability of puncture angle, simultaneously, has protected the sacculus effectively not to be damaged, is favorable to the repeated multiple spot puncture of blood vessel, and the validity of expansion and the uniformity of puncture angle have been guaranteed to the non-compliance sacculus.

Drawings

FIG. 1 is a schematic structural view of a dilation injection system for prevention and treatment of arterial stenosis of the present invention;

FIG. 2 is another schematic structural view of the dilation injection system of the present invention for preventing and treating stenosis of an artery;

FIG. 3 is a schematic structural view of another embodiment of the dilation injection system of the present invention for preventing and treating stenosis of an artery;

FIG. 4 is a schematic structural view of the first balloon of the dilation injection system for controlling stenosis of an artery of the present invention when folded;

FIG. 5 is a schematic structural view of the first balloon of the dilation injection system for controlling stenosis of an artery of the present invention inflated;

FIG. 6 is a first schematic view showing the structure of the needle seat and the puncture guide tube seat of the dilatation injection system for controlling arterial stenosis of the present invention;

FIG. 7 is a schematic view of a second embodiment of the needle seat and the puncture needle seat of the dilatation injection system for prevention and treatment of arterial stenosis of the present invention;

FIG. 8 is a partial schematic view of the expandable injection system for preventing and treating arterial stenosis according to the present invention with multiple needles;

fig. 9 is a partial structural schematic view of the dilation injection system for preventing and treating arterial stenosis of the present invention with two balloons.

In the drawings, the components represented by the respective reference numerals are listed below:

1. a conduit; 2. a first balloon; 3. a catheter adapter; 4. puncturing the guide tube; 5. puncturing needle; 6. a needle tube base; 7. a second balloon; 11. a first development mark ring; 12. a second development marker ring; 13. an outer tube; 14. an inner tube; 31. a water injection port; 32. a wire guide opening; 33. a medicine injection port; 34. a puncture guide tube seat; 51. a needle tube; 61. a socket portion; 341. the needle tube is inserted into the cavity.

Detailed Description

The principles and features of this invention are described below in conjunction with the following drawings, which are set forth by way of illustration only and are not intended to limit the scope of the invention.

The first embodiment is as follows: as shown in fig. 1, 2, 3, 4 and 5, the dilatation injection system for preventing and treating arterial stenosis of the present embodiment comprises a catheter 1, wherein the catheter 1 has a guide wire channel and a water injection channel extending along the long axis direction thereof; the first sacculus 2 is wrapped at one end of the catheter 1, the inner cavity of the first sacculus 2 is communicated with the water injection channel, and both ends of the first sacculus 2 are in a conical structure after water injection and expansion; a catheter adapter 3, wherein the catheter adapter 3 is connected to the other end of the catheter 1, and is provided with a water injection port 31 and a drug injection port 33, the water injection channel is communicated with the corresponding end of the water injection channel, and the drug injection port 33 is connected with a puncture guide tube seat 34; a guide wire port 32 communicated with the guide wire channel is arranged on the catheter joint 3 or the other end of the catheter 1, and the guide wire port 32 is communicated with the corresponding end of the guide wire channel; a puncture guide tube 4, the puncture guide tube 4 being provided in the catheter 1, one end of the puncture guide tube 4 penetrating one end of the catheter 1, and being attached and fixed to a tapered surface of the first balloon 2 near the one end thereof along the longitudinal direction of the catheter 1, the other end of the puncture guide tube 4 extending through the inside of the catheter 1 to be connected to the puncture guide tube holder 34; and a puncture needle 5 having a needle tube 51 connected to a needle end of the puncture needle 5, wherein the puncture needle 5 is inserted into the puncture guide tube holder 34, and pushed and pulled by an external force through the needle tube 51 until a needle tip thereof is pushed out or retracted from one end of the puncture guide tube 4.

The preoperative preparation process was as follows:

firstly, a guide wire is pushed to a treatment position along a blood vessel, then the catheter 1 is pushed in along the guide wire, and the first balloon 2 is confirmed to reach a designated position according to the developing position of the first balloon 2 under the DSA.

And secondly, injecting water into the water injection port 31, wherein the water enters the catheter 1 and the first balloon 2, and the first balloon 2 is expanded, so that the stenotic vessel can be expanded. Meanwhile, the first saccule 2 expands to expand and recover the conical structure at the end, and the section of the puncture guiding tube 4 attached to the conical surface bends along with the conical angle (forms an included angle with the catheter 1, namely forms an included angle with the trend of the blood vessel, and the included angle is about 30-45 degrees).

Thirdly, the needle tube 51 is connected with an injector of the liquid medicine, and the needle tube 51 is pushed, so that the needle tube 51 is slowly pushed along the direction of the puncture guide tube 4; until the puncture needle 5 punctures the adventitia of the blood vessel. At this time, the medicine in the syringe may be injected.

And fourthly, after the medicine is filled, retracting the needle tube puncture needle 5 and the needle tube 51 according to the original path, and pumping out the water in the first balloon 2 to restore the initial folding (dry and flat) state of the first balloon 2. And then exits the catheter 1 and guidewire in sequence.

If a plurality of places need to be injected with the medicine, the operations of water injection, needle pushing, medicine injection, needle withdrawing and water pumping can be repeated.

The whole system has reasonable structural design, ensures the stability of the puncture angle, simultaneously effectively protects the saccule from being damaged, is beneficial to repeated multi-point puncture of blood vessels, and ensures the effectiveness of expansion and the consistency of the puncture angle by the non-compliant saccule.

In the present embodiment, the conduit joint 3 involves at least the following two structures:

1) as shown in fig. 1 and 2, the catheter adapter 3 is a four-way adapter, one of the ports is connected to and communicates with the other end of the catheter 1 in a sealed manner, the remaining three ports respectively constitute the water injection port 31, the guide wire port 32, and the drug injection port 33, and the guide wire passage extends to be connected to and communicates with the guide wire port 32.

In this embodiment, the four-way joint is a special joint, and mainly comprises a straight main passage and two branches connected to the main passage, two ends of the main passage form two interfaces of the four-way joint, and the ends of the two branches form the remaining two interfaces (respectively comprising a water injection port 31 and a thread guide port 32), wherein one end of the main passage and the other end of the catheter 1 are mutually inserted (hermetically connected and communicated), and the other end of the main passage forms a drug injection port 33, so that different operations can be conveniently performed through different ports, and the interfaces are arranged in a reasonable order.

2) As shown in fig. 3, the catheter adapter 3 is a three-way adapter, one of the ports is connected to the other end of the catheter 1 in a sealing manner and communicates with the other two ports to form the water injection port 31 and the drug injection port 33, and the other end of the catheter 1 is provided with a guide wire quick-change port communicating with the guide wire channel and forming the guide wire port 32.

In the embodiment, the guide wire can be quickly and conveniently placed through the guide wire quick exchange port, the catheter does not need to be replaced at any time in the guide wire operation process, and the balloon dilatation catheter does not need to be replaced with the extension guide wire.

In a preferred embodiment, the puncture guide tube holder 34 is a cylindrical holder body, one end of which extends into the drug injection port 33 and is hermetically connected to the same, a cylindrical needle insertion cavity 341 is provided inside the other end of the puncture guide tube holder 34, and the other end of the puncture guide tube 4 passes through one end of the puncture guide tube holder 34 and communicates with the needle insertion cavity 341.

In this embodiment, access to the needle cannula 51 and the puncture needle 5 is facilitated through the needle access chamber 341.

In a preferred embodiment, at least two radiopaque first visualization marker rings 11 are provided along the longitudinal axis of the catheter 1 in the area of the surface of the catheter 1 within the envelope of the first balloon 2.

In this embodiment, the two first visualization marking rings 11 are reasonably designed, and are beneficial to positioning the first balloon 2 after filling.

Example two: as shown in fig. 6 and 7, the puncture needle further comprises a needle tube base 6, one end of the needle tube base 6 is internally provided with a lumen, the other end of the needle tube base 6 is provided with a columnar insertion part 61 matched with the needle tube insertion cavity 341, the needle tube insertion cavity 341 and the insertion part 61 are both in a matched columnar structure, one end of the needle tube 51 far away from the puncture needle 5 penetrates into the insertion part 61 and extends to be communicated with one end of the lumen close to the needle tube, the insertion part 61 is inserted into the needle tube insertion cavity 341 and slides along the needle tube insertion cavity 341 under the action of external force, so that the needle tube 51 is pushed and pulled to enable the needle tip of the puncture needle 5 to be pushed out or retracted from one end of the puncture guide tube 4, and multi-point puncture blood vessel injection can be realized on.

In this embodiment, the insertion portion 61 and the needle insertion chamber 341 are engaged to limit the penetration depth of the puncture needle 5 (i.e., the length of the puncture needle 5 penetrating through the needle insertion needle 5), and the needle holder 6 can push the puncture needle 5 and the needle tube 51, thereby facilitating the operation.

As a preferred embodiment, different clamping grooves are arranged at intervals on the inner wall of the needle tube insertion cavity 341 along the long axis direction thereof (i.e. the long axis direction of the catheter 1), and a convex flexible clamping part is arranged at a matching position on the socket part 61, and the clamping part can be clamped at different clamping grooves along with the depth of the needle tube insertion cavity 341, that is, the clamping grooves with different distances are arranged according to different distances required by the insertion needle, so that the distance of the puncture needle 5 for pushing and puncturing can be selected by a plurality of 'gears', and the needle tube insertion cavity has a limiting function and is more flexible to use.

It should be noted that: the needle tube 51 is made of nickel titanium material and has memory. The needle tube 51 moves in the puncture guide tube 4 in the direction of the guide tube.

The other steps are the same as those of the first embodiment.

Example three: as shown in fig. 8, a plurality of puncture guide tubes 4 are provided, one end of each puncture guide tube 4 penetrates through one end of the catheter 1, and one end of each puncture guide tube is uniformly attached and fixed to a tapered surface along the axial direction of the tapered structure at the corresponding end of the first balloon 2, a plurality of puncture needles 5 are provided in correspondence, the number of the puncture needles is equal to the number of the puncture guide tubes 4, the needle tube 51 is connected to the needle end of each puncture needle 5, and the puncture needles 5 enter the corresponding puncture guide tubes 4 through the puncture guide tube holders 34.

The embodiment realizes multi-point injection administration, can effectively avoid and penetrate plaques, ensures the success of drug injection, and simultaneously can ensure the combination treatment and multi-point treatment of various drugs.

The product consists of a balloon dilatation catheter and an injection system, firstly, the artery stenosis part is dilated through the balloon, and then the medicine is directly injected into the targeted blood vessel adventitia through the puncture needle 5, so that the medicine slowly and continuously infiltrates into the blood vessel intima, and the hyperplasia, the smooth muscle hyperplasia and the migration of the blood vessel are inhibited, and the restenosis of the blood vessel is prevented. Has the advantages of high local drug concentration, long drug action time, small systemic side effect and the like, can replace the prior drug eluting balloon technology, and improves the long-term recanalization rate of blood vessels. The stent has the remarkable advantages that the case of placing the stent is reduced or the stent is avoided, and the stent also has positive clinical effect on patients with blood vessel restenosis after the stent is placed.

On the basis of the four embodiments, the cooperation between the catheter 1 and the puncture guide tube 4 can include the following two structures:

1) as shown in fig. 1, 3, 4, 5, 8 and 9, the catheter 1 includes an outer tube 13 and an inner tube 14 disposed inside the outer tube 13, the other ends of the outer tube 13 and the inner tube 14 are connected to the catheter adapter 3, the outer tube 13 and the inner tube 14 are provided with a lumen through which the puncture guide tube 4 passes and the water injection channel, one end of the inner tube 14 extends out of one end of the outer tube 13, the first balloon 2 is wrapped around one end of the inner tube 14, and one end of the first balloon extends to be connected to and communicated with the water injection channel, and the inner tube 14 is provided with the guide wire channel along the longitudinal direction thereof; one end of the puncture guide tube 4 penetrates through the inner wall of the outer tube 13 through one end thereof, and extends along the surface of the extension part at one end of the first balloon 2 to be attached and fixed on the conical surface at one end of the first balloon 2 close to the first balloon.

2) As shown in fig. 2, the catheter 1 includes an outer tube 13 and an inner tube 14 disposed inside the outer tube 13, the other ends of the outer tube 13 and the inner tube 14 are connected to the catheter adapter 3 together, and a lumen for passing the puncture guide tube 4 is formed between the outer tube 13 and the inner tube 14, one end of the inner tube 14 extends outside one end of the outer tube 13, the first balloon 2 is wrapped around one end of the inner tube 14 and is disposed near one end of the outer tube 13, and the inner tube 14 is provided with the guide wire channel and the water injection channel along the longitudinal direction thereof; one end of the puncture guide tube 4 penetrates through the outer wall of one end of the outer tube 13 and extends along the outer wall of one end of the outer tube 13 to be attached and fixed to the conical surface of one end of the first balloon 2 close to the outer wall.

Example four: as shown in fig. 9, in addition to the above embodiment, the present invention further includes a second balloon 7, the second balloon 7 is wrapped around one end of the inner tube 14 and disposed at an end of the first balloon 2 away from the catheter adapter 3, and one end of the second balloon 7 extends to be connected to and communicated with the other end of the first balloon 2.

When the system in the embodiment is used, after the second balloon 7 reaches the designated position, water is injected into the water injection channel through the water injection port, the second balloon 7 is fully inflated firstly, the blood vessel stenosis part is expanded, and after the expansion is completed, the second balloon 7 is contracted; the catheter 1 is continuously pushed forwards, the second balloon 7 and the first balloon 2 are inflated and expanded through the water injection channel, the puncture needle 5 is operated to penetrate out of the end part of the puncture needle guide tube 4 to puncture the adventitia of the blood vessel after the first balloon 2 is expanded, and then the medicine is injected.

In a preferred embodiment, at least two radiopaque second visualization marker rings 12 are provided along the longitudinal axis of the catheter 1 in the area of the surface of the catheter 1 within the envelope of the second balloon 7.

The second balloon 7 is a sausage-shaped balloon, the length of the first balloon 2 can be shorter, and the second balloon 7 is not used for dilating a stenosed blood vessel but is only used as an expansion to facilitate the puncture needle 5 to penetrate out and pierce into an adventitia of the blood vessel.

The other steps are the same as those of the first embodiment.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. A dilation injection system for preventing and treating arterial stenosis, comprising:

the catheter (1) is internally provided with a guide wire channel and a water injection channel which extend along the long axis direction of the catheter (1);

the first balloon (2) is wrapped at one end of the catheter (1), the inner cavity of the first balloon (2) is communicated with the water injection channel, and both ends of the first balloon (2) are of conical structures after water injection and expansion;

the catheter joint (3) is connected to the other end of the catheter (1), a water injection port (31) and a medicine injection port (33) are formed in the catheter joint (3), the water injection port (31) is communicated with the corresponding end of the water injection channel, and the medicine injection port (33) is connected with a puncture guide tube seat (34);

a guide wire port (32) communicated with the guide wire channel is formed in the catheter joint (3) or the other end of the catheter (1), and the guide wire port (32) is communicated with the corresponding end of the guide wire channel;

the puncture guide tube (4) is arranged in the catheter (1), one end of the puncture guide tube (4) penetrates through the catheter (1) and is fixedly attached to a conical surface of one end, close to the first balloon (2), of the first balloon along the long axis direction of the catheter (1), and the other end of the puncture guide tube (4) extends to be connected with the puncture guide tube seat (34) through the interior of the catheter (1);

the puncture needle comprises a puncture needle (5), the needle tail of the puncture needle (5) is connected with a needle tube (51), the puncture needle (5) can enter from a puncture guide tube seat (34) and is pushed and pulled to the needle point through the needle tube (51) under the action of external force to be pushed out or retracted from one end of the puncture guide tube (4).

2. The dilatation injection system for preventing and treating arterial stenosis according to claim 1, wherein: one end of the puncture guide tube seat (34) extends into the medicine injection port (33), the puncture guide tube seat and the medicine injection port are mutually connected in a sealing mode, a needle tube intervention cavity (341) is formed in the other end of the puncture guide tube seat (34), and the other end of the puncture guide tube (4) penetrates through one end of the puncture guide tube seat (34) and is communicated with the needle tube intervention cavity (341).

3. The dilatation injection system for preventing and treating arterial stenosis according to claim 2 wherein: the puncture needle comprises a puncture guide tube (4) and is characterized by further comprising a needle tube seat (6), a tube cavity is formed in one end of the needle tube seat (6), a columnar insertion part (61) matched with the needle tube intervention cavity (341) is arranged at the other end of the needle tube seat, one end, far away from the puncture needle (5), of the needle tube (51) penetrates into the insertion part (61) and extends to be communicated with one end, close to the tube cavity, of the tube cavity, the insertion part (61) is used for being inserted into the needle tube intervention cavity (341) and slides along the needle tube intervention cavity (341) under the action of external force, and therefore the needle tube (51) is pushed and pulled so that the needle point of the puncture needle (5) is pushed out or retracted from one end.

4. A dilatation injection system for prevention and treatment of arterial stenosis according to anyone of the claims 1 to 3 characterized in that: the surface of the catheter (1) is provided with at least two radiopaque first developing mark rings (11) in the long axis direction in the area of the first balloon (2).

5. A dilatation injection system for prevention and treatment of arterial stenosis according to anyone of the claims 1 to 3 characterized in that: the puncture guide tube (4) is provided with a plurality of puncture guide tubes, one end of each puncture guide tube penetrates through one end of the catheter (1) respectively, the puncture guide tubes are uniformly attached and fixed on a conical surface along the axial direction of the conical structure at the corresponding end of the first balloon (2) respectively, the puncture needles (5) are correspondingly provided with a plurality of puncture needles, the number of the puncture needles is consistent with that of the puncture guide tubes (4), the needle tail of each puncture needle (5) is connected with the needle tube (51), and the puncture needles (5) penetrate through the puncture guide tube seats (34) respectively and enter the corresponding puncture guide tubes (4).

6. A dilatation injection system for prevention of arterial stenosis according to claims 1 to 3 characterized in that: the catheter joint (3) is a four-way joint, one interface of the catheter joint is hermetically connected and communicated with the other end of the catheter (1), the other three interfaces respectively form the water injection port (31), the guide wire port (32) and the medicine injection port (33), and the guide wire channel extends to be connected and communicated with the guide wire port (32); or the catheter joint (3) is a three-way joint, one interface of the three-way joint is hermetically connected with the other end of the catheter (1) and communicated with the other two interfaces to form the water injection port (31) and the medicine injection port (33) respectively, the other end of the catheter (1) is provided with a guide wire fast exchange port communicated with the guide wire channel, and the guide wire fast exchange port forms the guide wire port (32).

7. A dilatation injection system for prevention and treatment of arterial stenosis according to anyone of the claims 1 to 3 characterized in that: the catheter (1) comprises an outer tube (13) and an inner tube (14) arranged inside the outer tube (13), the other ends of the outer tube (13) and the inner tube (14) are connected with the catheter connector (3) together, an inner cavity for the puncture guide tube (4) to pass through and the water injection channel are arranged on the outer tube (13) and the inner tube (14), one end of the inner tube (14) extends out of one end of the outer tube (13), the first balloon (2) is wrapped and arranged outside one end of the inner tube (14), one end of the first balloon extends to be connected and communicated with the water injection channel, and the guide wire channel is arranged in the inner tube (14) along the long axis direction of the inner tube; one end of the puncture guide tube (4) penetrates through the outer wall of one end of the outer tube (13) and extends to be attached and fixed to a conical surface of one end, close to the outer tube, of the first balloon (2) along the outer wall of one end of the outer tube (13), or one end of the puncture guide tube (4) penetrates out of one end of the inner wall of the outer tube (13) along one end of the inner wall of the outer tube and extends to be attached and fixed to a conical surface of one end, close to the outer tube, of the first balloon (2) along the surface of one end extending portion of the first balloon (2).

8. The dilatation injection system of claim 7 wherein: the catheter joint further comprises a second balloon (7), the second balloon (7) is wrapped at one end of the inner tube (14) and is arranged at one end, far away from the catheter joint (3), of the first balloon (2) at intervals, and one end of the second balloon (7) extends to be connected with and communicated with the other end of the first balloon (2).

9. The dilatation injection system of claim 8 wherein: the surface of the catheter (1) is provided with at least two radiopaque second developing mark rings (12) in the long axis direction in the area of the second balloon (7).