CN112136980A - Additive premix for improving sow production performance - Google Patents

Additive premix for improving sow production performance Download PDF

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Publication number
CN112136980A
CN112136980A CN202011095659.1A CN202011095659A CN112136980A CN 112136980 A CN112136980 A CN 112136980A CN 202011095659 A CN202011095659 A CN 202011095659A CN 112136980 A CN112136980 A CN 112136980A
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China
Prior art keywords
additive
sows
premix
improving
productivity
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CN202011095659.1A
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Chinese (zh)
Inventor
冉学光
王丽
杨雪芬
高开国
易宏波
肖昊
胡友军
温晓鹿
蒋宗勇
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Institute of Animal Science of Guangdong Academy of Agricultural Sciences
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Institute of Animal Science of Guangdong Academy of Agricultural Sciences
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Priority to CN202011095659.1A priority Critical patent/CN112136980A/en
Publication of CN112136980A publication Critical patent/CN112136980A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/121Heterocyclic compounds containing oxygen or sulfur as hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/28Silicates, e.g. perlites, zeolites or bentonites
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses an additive premix for improving the productivity of sows, which comprises a carrier and an additive composition. The additive composition consists of 5-20 mg/kg of N-carbamylglutamic acid, 10-100mg/kg of 4 ', 5, 7-trihydroxyisoflavone, 10-50 mg/kg of 4', 7-dihydroxyisoflavone, 0.5-1 mg/kg of folic acid, 10-100mg/kg of vitamin E, 0.5-1 mg/kg of biotin and 800 mg/kg of ferrous glycinate. The invention also provides a using method of the additive, and compared with singly adding any one component, the additive premix using the composition has better effect, reduces the dosage of each additive and saves the cost. The additive premix can provide high-quality nutrition guarantee for the development of embryos, placentas and fetuses in sows, remarkably improve the litter size and the number of live litters of sows, improve the weight of newborn litters, newborn individual weights and placenta weights to a certain extent, and effectively improve the production performance of sows.

Description

Additive premix for improving sow production performance
Technical Field
The invention relates to the technical field of feed additive premix, in particular to additive premix for improving the production performance of sows.
Background
The production performance of the sow is one of the important factors influencing the economic benefit of the pig industry. At present, the reproductive capacity of sows is mainly used as a standard to evaluate the production performance of sows. Including the contents of the number born, the number of the litters born per year, the birth weight and the lactation capacity. Ways to improve the productivity of sows have also been studied mainly around these aspects. Such as: the oestrus time and the farrowing interval are shortened, and the number of yearly farrowing nests is increased; increasing the ovulation number of sows by a breeding technology; timely breeding is carried out, and the fertilization rate of the discharged eggs is improved; properly increase the exercise, improve the feeding management of pregnant sows, strengthen the physique of the sows and improve the survival rate of embryos. These objectives must be achieved by providing corresponding nutrient control measures. Therefore, the research on the feed or additive premix for improving the production performance of the sows is of great significance.
Patent application CN201911093296.5 discloses a plant extract feed additive for improving reproductive performance of sows, which consists of angelica sinensis, astragalus polysaccharide, motherwort, soybean isoflavone, cowherb seed, glossy privet fruit polysaccharide, rhizoma polygonati and a proper amount of carrier. The influence of the feed on the sows is reflected in the following aspects: can improve the feed intake in the lactation period, reduce the loss of backfat, promote the immunity of organisms, promote the development of mammary tissue, increase the milk yield and improve the contents of milk fat and milk protein in the normal milk; patent application CN201910806409.5 discloses a Chinese herbal medicine for improving the reproductive performance of sows, which comprises the following components: honeysuckle, scutellaria baicalensis, astragalus mongholicus, motherwort herb, mangnolia officinalis, angelica sinensis, turmeric and glossy privet fruit, and the action mechanism of the traditional Chinese medicine composition can improve the antioxidant and anti-stress capacity of sows, improve the physique of the sows and improve the production performance and the reproductive performance. The idea of the invention is to prepare the additive from the perspective of Chinese herbal medicine, but the active ingredients of the additive are unclear, and the formula compatibility is only empirical, the effect is uncertain and side effects are easy to generate.
Patent application CN 201711069021.9 discloses a compound feed for improving the productivity of sows, which comprises vitamin E, folic acid, biotin, L-valine, chromium picolinate, dihydropyridine, chlorogenic acid, red clover extract, probiotics, glucose and the like. The action mechanism of the compound feed is to enhance the resistance of the sow, and is beneficial to improving the conception rate and the number of the farrowing of the sow and improving the survival rate of the young sows.
Patent application CN201710442446.3 discloses a feed additive for nursing sows, which comprises lactobacillus plantarum metabolite antibacterial peptide, lactobacillus rhamnosus, glucose oxidase, catalase, peptide peptidase, epoxidase, phosphatase, and the like. The mechanism is to prevent the influence of mycotoxin and vivotoxin on the lactating sow, so that the immunity and the lactation yield of the lactating sow are obviously increased, and the weaning weight of the piglet is obviously improved.
Disclosure of Invention
The invention aims to solve the technical problem of providing an additive premix for improving the production performance of sows, and the invention is designed to provide high-quality nutrition guarantee for the development of embryos, placentas and fetuses in the sows through a comprehensive application technology of component combination and synergistic effect with definite functions, improve the oxidation resistance of sows and improve the lactation performance of the sows so as to achieve the aim of improving the production performance of the sows.
In order to solve the problems, the additive premix for improving the productivity of the sows, provided by the invention, comprises a carrier and an additive composition, wherein the additive composition comprises glycine consisting of N-carbamylglutamic acid, 4 ', 5, 7-trihydroxyisoflavone, 4', 7-dihydroxyisoflavone, folic acid, vitamin E, biotin and ferrous glycinate.
The carrier is one or a mixture of stone powder, zeolite powder, bentonite, bran, corn starch or defatted rice bran.
The additive composition comprises 5-20 mg/kg of N-carbamylglutamic acid, 10-100mg/kg of 4 ', 5, 7-trihydroxyisoflavone, 10-50 mg/kg of 4', 7-dihydroxyisoflavone, 0.5-1 mg/kg of folic acid, 10-100mg/kg of vitamin E, 0.5-1 mg/kg of biotin and 800 mg/kg of ferrous glycinate.
The N-carbamylglutamic acid in the invention is a structural analogue of N-acetyl glutamic acid, the former can replace the latter to become an allosteric catalyst of carbamyl phosphate synthetase, thereby promoting the conversion of proline and glutamine to citrulline and arginine, increasing the endogenous synthesis of arginine, and arginine has important function on the development of embryo, placenta and fetus.
The sow body is easy to suffer from severe oxidative stress in the perinatal period and the lactation period, and the lactation performance of the sow is influenced. Therefore, the antioxidation is also the problem to be solved for improving the productivity of the sows. In the invention, 4 ', 5, 7-trihydroxyisoflavone and 4', 7-dihydroxyisoflavone are added as polyphenol substances, and the two substances have different numbers of substituted hydroxyl groups and different positions to influence the distribution of electron cloud of a ring, so that the antioxidant capacity cannot be analogized by the number of phenolic hydroxyl groups and similar structures simply, and the combined application of the two substances forms a new antioxidant system which has stronger antioxidant capacity than that of a single component and has more simple effect superposition than that of the two substances. The compound can effectively react with free radicals in vivo and in vitro to generate corresponding ions and molecules, inhibit the generation of the free radicals, eliminate and extinguish the free radicals, terminate the chain reaction of the free radicals, promote the secretion of antioxidant enzymes, inhibit lipid peroxidation, improve the proliferation of mammary epithelial cells of sows, and reduce apoptosis, thereby improving the development of the breasts of the sows and the oxidation resistance of organisms, and improving the weight gain and the survival rate of suckling piglets.
Vitamin E is a potent antioxidant that is an important component of the antioxidant defense system of tissues and cells. Folic acid is involved in purine, pyrimidine and amino acid metabolic processes, so that the synthesis of DNA, RNA and various proteins of sow embryos is promoted, and the embryo formation and the growth and development of fetuses are directly influenced. The biotin is used as a coenzyme and participates in various main metabolic processes, so that the production performance of the sow can be improved, and the disease frequency of the sow can be reduced.
Ferrous glycinate is an amino acid chelated iron source, is easier to absorb than inorganic iron sources such as ferrous sulfate and organic acid iron sources such as ferrous fumarate and ferrous citrate, and is easier to transmit to piglets through sow placentas and sows, thereby promoting the growth and development of piglets, preventing iron-deficiency anemia and reducing the death rate of piglets.
The application method of the additive premix for improving the productivity of the sows, provided by the invention, is respectively adding the additive premix into 4% of premix, 10% of concentrated feed and complete compound feed according to the proportion of 20-50 kg/ton, 5-10 kg/ton and 2-5 kg/ton.
The invention has the advantages and beneficial effects that: the composition composed of the bioactive substances has the functions of not simply superposing all the components but realizing the synergistic effect of all the components, is a set of comprehensive application technology, and the additive premix added with the composition has better effect than the additive premix added with any one component singly, and reduces the dosage of each additive, thereby saving the cost.
Detailed Description
The present invention is described below by way of specific examples, which are provided only for the purpose of further illustrating the present invention and do not represent the scope of the present invention, and other insubstantial modifications and adaptations made in accordance with the present invention would still fall within the scope of the present invention.
Example 1
An additive premix for improving the production performance of sows comprises a carrier and an additive composition, wherein in the composition, N-carbamylglutamic acid 5 mg/kg, 4 ', 5, 7-trihydroxyisoflavone 100mg/kg, 4', 7-dihydroxyisoflavone 10mg/kg, folic acid 1 mg/kg, vitamin E10 mg/kg, biotin 1 mg/kg and ferrous glycine 800 mg/kg, the carrier is corn starch, the mixture is uniformly mixed, and the mixture is added into a complete formula feed according to the proportion of 2 kg/ton.
Example 2
An additive premix for improving the production performance of sows comprises a carrier and an additive composition, wherein in the composition, N-carbamylglutamic acid is 20 mg/kg, 4 ', 5, 7-trihydroxyisoflavone is 10mg/kg, 4', 7-dihydroxyisoflavone is 50 mg/kg, folic acid is 0.5 mg/kg, vitamin E is 100mg/kg, biotin is 0.5 mg/kg, ferrous glycinate is 200 mg/kg, the carrier is zeolite powder, the mixture is uniformly mixed, and the zeolite powder is added into 10% concentrated feed according to the proportion of 10 kg/ton.
Example 3
An additive premix for improving the production performance of sows comprises a carrier and an additive composition, wherein in the composition, N-carbamylglutamic acid is 10mg/kg, 4 ', 5, 7-trihydroxyisoflavone is 40 mg/kg, 4', 7-dihydroxyisoflavone is 20 mg/kg, folic acid is 0.6 mg/kg, vitamin E is 80 mg/kg, biotin is 0.5 mg/kg, ferrous glycinate is 300 mg/kg, the carrier is defatted rice bran, the mixture is uniformly mixed, and the mixture is added into 4% of the premix according to the proportion of 30 kg/ton.
Example 4
An additive premix for improving the production performance of sows comprises a carrier and an additive composition, wherein the additive composition comprises 15 mg/kg of N-carbamylglutamic acid, 60 mg/kg of 4 ', 5, 7-trihydroxyisoflavone, 30 mg/kg of 4', 7-dihydroxyisoflavone, 1 mg/kg of folic acid, 40 mg/kg of vitamin E, 0.5 mg/kg of biotin and 500 mg/kg of ferrous glycinate, the carrier is bentonite, the additive premix is uniformly mixed, and the bentonite is added into a complete formula feed according to the proportion of 5 kg/ton.
Example 5
An additive premix for improving the production performance of sows comprises a carrier and an additive composition, wherein in the composition, N-carbamylglutamic acid 8 mg/kg, 4 ', 5, 7-trihydroxyisoflavone 30 mg/kg, 4', 7-dihydroxyisoflavone 20 mg/kg, folic acid 1 mg/kg, vitamin E60 mg/kg, biotin 0.5 mg/kg and ferrous glycine 700 mg/kg are mixed uniformly, and the carrier is bran and is added into 4 percent of the premix according to the proportion of 50 kg/ton.
Example 6
An additive premix for improving the production performance of sows comprises a carrier and an additive composition, wherein the composition comprises 20 mg/kg of N-carbamylglutamic acid, 60 mg/kg of 4 ', 5, 7-trihydroxyisoflavone, 30 mg/kg of 4', 7-dihydroxyisoflavone, 0.5 mg/kg of folic acid, 10mg/kg of vitamin E, 0.5 mg/kg of biotin and 800 mg/kg of ferrous glycinate, the carrier is corn starch, the mixture is uniformly mixed, and the mixture is added into a complete formula feed according to the proportion of 2 kg/ton.
Example 7
An additive premix for improving the production performance of sows comprises a carrier and an additive composition, wherein in the composition, N-carbamylglutamic acid 10mg/kg, 4 ', 5, 7-trihydroxyisoflavone 60 mg/kg, 4', 7-dihydroxyisoflavone 40 mg/kg, folic acid 1 mg/kg, vitamin E70 mg/kg, biotin 1 mg/kg and ferrous glycine 200 mg/kg, the carrier is bran, the components are uniformly mixed and added into 4% concentrated feed according to the proportion of 5 kg/ton.
Application examples
The experimental site is a pig farm tested by the institute of animal science of the academy of agricultural sciences of Guangdong province, 60 pregnant sows are selected, the sows are immediately divided into a control group and an experimental group after pregnancy for 60 days, 30 sows in each group are selected, 10 sows in each group are repeated, 3 sows are repeated, a single-factor experimental design is adopted, basic daily ration (the control group) and the basic daily ration plus 4% of premix (the experimental group) in example 3 are respectively fed, the environmental conditions of the experimental pigs are consistent, the sows freely drink water, and the conventional health care immunity is performed, and the cleanness and sanitation of the environment are well made.
The method for measuring the indicators of the sow production performance mainly comprises the following steps: total litter size, litter weight, individual weight, and methods of data analysis and processing were recorded using methods common in the art.
The results of total litter size, number of live litter, weight of newborn individual, and placenta of the control and test groups are shown in the following table:
control group Test group
Number of sow tested (head) 30 30
Litter size (head) 11.47 b 13.16 a
Living boy number (head) 11.3 b 12.8 a
Weight of newborn litter (kilogram) 13.75 14.55
Birth individual weight (kilogram) 1.36 1.47
Placenta weight (kilogram) 2. 05 2.27
Note: the data in the same row shows no significant difference (P is more than 0.05) when the letters are not marked on the shoulder, and shows significant difference (P is less than 0.05) when the letters are marked with different lower case letters
As can be seen from the table: the test group can obviously improve the litter size and the litter live number of the sow, the litter size and the live number are improved by more than 1, and the difference is extremely obvious (P is less than 0.01). The weight of the newborn nest, the newborn individual weight and the weight of the placenta are improved to a certain extent, but the difference is not obvious. The additive premix feed for improving the productivity of sows disclosed by the invention has an obvious improvement effect on the productivity of sows.

Claims (6)

1. An additive premix for improving the productivity of sows comprises a carrier and an additive composition, and is characterized in that: the additive composition consists of N-carbamylglutamic acid, 4 ', 5, 7-trihydroxyisoflavone, 4', 7-dihydroxyisoflavone, folic acid, vitamin E, biotin and ferrous glycinate.
2. The additive premix for improving the productivity of sows as set forth in claim 1, wherein: the carrier is one or a mixture of stone powder, zeolite powder, bentonite, bran, corn starch or defatted rice bran.
3. The additive premix for improving the productivity of sows as set forth in claim 1, wherein: the additive amount of each component in the additive composition is 5-20 mg/kg of N-carbamylglutamic acid, 10-100mg/kg of 4 ', 5, 7-trihydroxyisoflavone, 10-50 mg/kg of 4', 7-dihydroxyisoflavone, 0.5-1 mg/kg of folic acid, 10-100mg/kg of vitamin E, 0.5-1 mg/kg of biotin and 800 mg/kg of ferrous glycinate.
4. An additive premix for improving productivity of sows according to claim 1 or 2 or 3, wherein: the premix is added into 4 percent of premix according to the proportion of 20-50 kg/ton.
5. An additive premix for improving productivity of sows according to claim 1 or 2 or 3, wherein: the premix is added into 10 percent concentrated feed according to the proportion of 5-10 kg/ton.
6. An additive premix for improving productivity of sows according to claim 1 or 2 or 3, wherein: the premix is added into complete feed according to the proportion of 2-5 kg/ton.
CN202011095659.1A 2020-10-14 2020-10-14 Additive premix for improving sow production performance Pending CN112136980A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113475635A (en) * 2021-07-02 2021-10-08 广东省农业科学院动物科学研究所 Additive premix for relieving oxidative stress of sows

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108497186A (en) * 2018-03-23 2018-09-07 广东新南都饲料科技有限公司 A kind of additive premix improving sow reproductive performance
CN108617874A (en) * 2018-05-11 2018-10-09 广东新南都饲料科技有限公司 A kind of additive premix reducing sow oxidative stress
CN109221706A (en) * 2018-09-20 2019-01-18 广东新南都饲料科技有限公司 A kind of additive premix improving sow milk performance

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108497186A (en) * 2018-03-23 2018-09-07 广东新南都饲料科技有限公司 A kind of additive premix improving sow reproductive performance
CN108617874A (en) * 2018-05-11 2018-10-09 广东新南都饲料科技有限公司 A kind of additive premix reducing sow oxidative stress
CN109221706A (en) * 2018-09-20 2019-01-18 广东新南都饲料科技有限公司 A kind of additive premix improving sow milk performance

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113475635A (en) * 2021-07-02 2021-10-08 广东省农业科学院动物科学研究所 Additive premix for relieving oxidative stress of sows

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