CN112089749A - Chinese and western medicine compound medicine for treating rheumatoid bone diseases and preparation method thereof - Google Patents
Chinese and western medicine compound medicine for treating rheumatoid bone diseases and preparation method thereof Download PDFInfo
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Abstract
The invention provides a Chinese and western medicine compound medicine for treating rheumatism bone disease, which consists of traditional Chinese medicine components and western medicine components, wherein the traditional Chinese medicine components comprise liquorice, zaocys dhumnade, pseudo-ginseng, gentiana macrophylla, astragalus mongholicus and safflower carthamus, and the western medicine components comprise ibuprofen, calcium gluconate and aluminum hydroxide. The Chinese and western medicine compound medicine for treating the rheumatoid bone disease organically combines natural Chinese herbal medicines and western medicines, adjusts the compatibility and the applicability of the Chinese and western medicines, and achieves the effect of treating rheumatism and osteoporosis by adding calcium gluconate and aluminum hydroxide; aiming at the properties of the traditional Chinese medicine, different treatment modes are adopted, the active ingredients of the traditional Chinese medicine are retained to the maximum extent, the preparation method of the medicine is simple, and the cure effect of patients with mild, moderate and severe rheumatic bone diseases is improved by removing dampness and removing arthralgia, and dredging collaterals and eliminating evil.
Description
Technical Field
The invention relates to the technical field of medicines, in particular to a Chinese and western medicine compound medicine for treating rheumatoid bone diseases.
Background
Rheumatism is a group of diseases mainly attacking joints, bones, muscles, blood vessels and related soft tissues or connective tissues, and most of them are autoimmune diseases. The disease is more hidden and slow, the disease course is longer, most of the diseases have hereditary tendency, and the diagnosis and the treatment are difficult to some extent. The traditional Chinese medicine considers that the arthralgia syndrome comprises migratory arthralgia, painful arthralgia, migratory arthralgia, wangbi and the like, and is characterized in that damp-heat is accumulated among limbs, joints, meridians and muscles and bones, stays undeveloped for a long time, is depressed to generate dryness, robbes and damages body fluid, muscles and joints are not nourished, qi stagnation and blood stasis are caused, and coagulation is not performed, so that qi and limb joints are deformed and contracture is caused. At present, western medicine treatment, physical treatment, massage acupuncture treatment, operation treatment and the like are available for treating rheumatism, but the method has the disadvantages of great side effect or high cost and incomplete treatment, and brings great pain and heavy burden to patients and families.
At present, some patent applications are also directed to rheumatoid diseases, for example, the medicine for treating rheumatism and rheumatoid diseases disclosed in CN 102805817B is prepared from expensive traditional Chinese medicine raw materials such as ganoderma lucidum, the treatment period of mild patients is more than half a year, the treatment period is long, and the treatment cost of patients is increased; for example, CN 105148199A discloses a compound Chinese and western medicine for treating rheumatoid arthritis, which has good diagnosis and treatment effects on patients with mild rheumatic arthritis with a disease history of 1 month to 2 years, but the compound Chinese and western medicine comprises 23 traditional Chinese medicine components and 10 western medicine components, has a complex formula, is added with hormone medicines such as prednisone acetate and the like, and has complicated processes of tormentum tormentosum extraction and lumbrokinase preparation, thereby increasing the production cost of the medicine.
Therefore, there is a need to develop a medicament for treating rheumatism, which has a simple formula, a good curative effect and a simple preparation process. The invention provides a compound medicine of Chinese and western medicines for treating rheumatic bone diseases, which integrates the clinical treatment concepts of the Chinese and western medicines, adopts the ideas of treating both symptoms and root causes of western medicines, quickly relieves the discomfort such as pain and swelling of patients in the treatment process, fundamentally improves the immunity of the patients, eliminates dampness and arthralgia, unblocks collaterals and eliminates pathogenic factors, and improves the cure effect of patients with mild, moderate and severe rheumatic bone diseases.
Disclosure of Invention
The invention provides a Chinese and western medicine compound medicine for treating rheumatic osteopathy, which is good in curative effect, simple in formula and suitable for batch production, and aims to solve the problems that the medicine for treating stroke-wet osteopathy in the prior art is complex in formula, long in treatment period, unobvious in treatment effect on severe patients, expensive in patient treatment and the like.
A Chinese and western medicine compound medicine for treating rheumatoid bone diseases is composed of traditional Chinese medicine components and western medicine components, wherein the traditional Chinese medicine components are mainly prepared by extracting the following raw material medicines in parts by weight: 3-10 parts of liquorice, 2-8 parts of zaocys dhumnade, 1-4 parts of pseudo-ginseng, 2-5 parts of gentiana macrophylla, 5-10 parts of astragalus membranaceus and 2-4 parts of safflower, wherein the western medicine components are mainly prepared by mixing the following raw material medicines in parts by weight: 0.1-0.3 part of ibuprofen, 0.1-0.3 part of calcium gluconate and 0.2-0.5 part of aluminum hydroxide.
Further, the Chinese and western medicine compound medicine for treating the rheumatoid bone disease is prepared by extracting the following raw material medicines in parts by weight: 5-8 parts of liquorice, 4-6 parts of zaocys dhumnade, 2-3 parts of pseudo-ginseng, 3-4 parts of gentiana macrophylla, 7-9 parts of astragalus membranaceus and 3-4 parts of safflower, wherein the western medicine components are mainly prepared by mixing the following raw material medicines in parts by weight: 0.15-0.25 part of ibuprofen, 0.15-0.25 part of calcium gluconate and 0.3-0.4 part of aluminum hydroxide.
A preparation method of a Chinese and western medicine compound medicine for treating rheumatoid bone diseases comprises the following steps:
(1) weighing the following raw material medicines in parts by weight: cleaning, airing and crushing raw material medicines of liquorice, pseudo-ginseng, gentiana macrophylla and astragalus membranaceus to obtain raw material medicine particles A, mixing and decocting the raw material medicine particles A with 6-9 times of purified water for 2-4 hours, centrifuging for 10-16min at the rotating speed of 3000-5000r/min, and separating to obtain precipitates B and a supernatant C; mixing the precipitate B with purified water 6-9 times the amount of the precipitate B, decocting for 2-3h, centrifuging at the rotating speed of 3000-5000r/min for 10-16min, and separating to obtain a precipitate D and a supernatant E; mixing the supernatant C and E, and vacuum concentrating under reduced pressure at steam pressure of 0.20MPa or less, vacuum degree of 710-800mmhg, and temperature of 60-79 deg.C to obtain Chinese medicinal extract F with density of 1.02-1.2g/cm3；
(2) Weighing the following raw material medicines in parts by weight: mixing Zaocys, Carthami flos, ibuprofen, calcium gluconate and aluminum hydroxide, pulverizing, and sieving with 100 mesh sieve to obtain crude drug powder G smaller than 100 mesh;
(3) mixing the Chinese medicinal extract F and the crude drug powder G uniformly, making into granules with particle size of 14-60 meshes, and bagging according to the specification of 5-7G per bag.
Further, the preparation method of the Chinese and western medicine compound medicine for treating the rheumatoid bone disease comprises the step (3) of uniformly mixing the traditional Chinese medicine extract F and the bulk drug powder G, and directly preparing pills of 5-7G/pill.
The pharmacological actions of the traditional Chinese medicine and the western medicine are as follows:
the liquorice has the functions of tonifying spleen and qi, clearing heat and detoxicating, eliminating phlegm and stopping cough, relieving spasm and pain, and harmonizing the drugs, and is used for treating weakness of spleen and stomach, lassitude and weakness, palpitation and shortness of breath, cough and excessive phlegm, abdominal and limb spasm and pain, carbuncle swelling and sore toxicity, and relieving drug toxicity and intensity.
Zaocys dhumnades has effects of dispelling pathogenic wind, dredging collaterals, and relieving spasm. Can be used for treating rheumatism, numbness, spasm, apoplexy, facial distortion, hemiplegia, convulsion, spasm, tetanus, and leprosy.
Notoginseng radix has effects of dispelling blood stasis, stopping bleeding, relieving swelling and pain, and can be used for hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, brain and abdominal pain, and traumatic injury with swelling and pain.
Qin jiao can dispel wind-damp, clear damp-heat, relieve arthralgia and alleviate deficiency heat. Can be used for treating rheumatalgia, apoplexy, hemiplegia, spasm of tendons and vessels, soreness of bone joints, jaundice due to damp-heat pathogen, hectic fever due to yin-deficiency, and infantile malnutrition with fever.
The astragalus root has the functions of invigorating qi and raising yang, consolidating superficial resistance and arresting sweating, inducing diuresis and reducing edema, promoting the production of body fluid and nourishing blood, activating stagnancy and removing obstruction of qi, expelling toxin and pus, healing sore and promoting granulation. Can be used for treating deficiency of vital energy, asthenia, anorexia, loose stool, apoplexy, chronic diarrhea, rectocele, hematochezia, metrorrhagia, exterior deficiency, spontaneous perspiration, qi deficiency, edema, internal heat, diabetes, blood deficiency, hemiplegia, arthralgia, numbness, pain, cellulitis, intractable ulcer, and chronic ulcer.
Safflower, for dispersing blood stasis, eliminating obstruction, removing food retention, relieving pain, inducing diuresis and relieving swelling. Can be used for treating lump and lump, goiter and tumor, dyspepsia, gastralgia, abdominal pain, edema and ascites.
Ibuprofen is a non-steroidal antipyretic analgesic to relieve various pains, joint ache and the like.
Calcium gluconate, a calcium supplement drug, increases bone density and prevents or treats osteoporosis.
Aluminum hydroxide is a gastric mucosa protective agent, prevents the medicine from stimulating bone mucosa to cause injury, and prevents gastrorrhagia and the like.
The invention has the beneficial effects that:
1. the natural Chinese herbal medicines and the western medicines are organically combined, the compatibility and the applicability of the Chinese herbal medicines and the western medicines are adjusted, the Chinese herbal medicine and the western medicine compound medicine for treating the rheumatic bone disease are prepared, and the cure effect of patients with mild, moderate and severe rheumatic bone diseases is improved by removing dampness and removing arthralgia and dredging collaterals and eliminating evil;
2. calcium gluconate and aluminum hydroxide are added into the formula of the Chinese and western medicine compound medicine for treating the rheumatic bone disease, so that the bone density is increased, the gastric mucosa is protected, and the effect of treating rheumatism and osteoporosis is achieved;
3. according to the invention, different treatment modes are adopted according to the property of the traditional Chinese medicine, the effective components of the liquorice, the pseudo-ginseng, the gentiana macrophylla and the astragalus membranaceus are extracted, and when the zaocys dhumnade and the safflower are treated, the effective components of the traditional Chinese medicine are reserved to the maximum extent, and the treatment effect of the medicine is improved.
4. The Chinese and western medicine compound medicine formula for treating the rheumatoid bone disease is prepared from Chinese medicines and non-hormone western medicines, has a good treatment effect, does not cause adverse reactions, and has high acceptance of patients on the medicine.
The specific implementation mode is as follows:
the present invention will be described in further detail with reference to specific examples.
Example 1:
(1) weighing 4 parts of liquorice, 3 parts of pseudo-ginseng, 4 parts of gentiana macrophylla and 8 parts of astragalus mongholicus, cleaning, airing and crushing to 1mm of granularity to obtain raw material medicine particles A, mixing and decocting the raw material medicine particles A with 8 times of purified water for 3 hours, centrifuging for 10min at the rotating speed of 4000r/min, and separating to obtain a precipitate B and a supernatant C; mixing the precipitate B with 6 times of purified water, decocting for 3h, centrifuging at 5000r/min for 12min, and separating to obtain precipitate D and supernatant E; mixing the supernatant C and E, and vacuum concentrating under 0.20MPa of steam pressure, 800mmhg of vacuum degree and 75 deg.C to obtain Chinese medicinal extract F with density of 1.05g/cm3；
(2) Weighing 5 parts of zaocys dhumnade, 4 parts of safflower, 0.3 part of ibuprofen, 0.2 part of calcium gluconate and 0.4 part of aluminum hydroxide, mixing, crushing, and sieving with a 100-mesh sieve to obtain bulk drug powder G with the particle size of less than 100 meshes;
(3) and uniformly mixing the traditional Chinese medicine extract F and the bulk drug powder G, preparing into particles with the particle size of 14-60 meshes, and bagging according to the specification of 6G per bag to obtain the traditional Chinese and western medicine compound medicine for treating the rheumatoid bone disease.
Example 2:
(1) weighing 7 parts of liquorice, 3.5 parts of pseudo-ginseng, 4.5 parts of gentiana macrophylla and 7 parts of astragalus membranaceus, cleaning, airing and crushing to 1mm granularity to obtain raw material medicine particles A, mixing and decocting the raw material medicine particles A with 9 times of purified water for 3.5 hours, centrifuging for 10min at the rotating speed of 4000r/min, and separating to obtain a precipitate B and a supernatant C; mixing the precipitate B with 6 times of purified water, decocting for 2.5h, centrifuging at 5000r/min for 12min, and separating to obtain precipitate D and supernatant E; mixing the supernatant C and E, and vacuum concentrating under steam pressure of 0.18MPa, vacuum degree of 800mmhg, and temperature of 76 deg.C to obtain Chinese medicinal extract F with density of 1.05g/cm3；
(2) Weighing 5.5 parts of zaocys dhumnade, 3.5 parts of safflower, 0.25 part of ibuprofen, 0.15 part of calcium gluconate and 0.35 part of aluminum hydroxide, mixing, crushing, and sieving with a 100-mesh sieve to obtain raw material medicine powder G with the particle size less than 100 meshes;
(3) and uniformly mixing the traditional Chinese medicine extract F and the bulk drug powder G, preparing into particles with the particle size of 14-60 meshes, and bagging according to the specification of 6G per bag to obtain the traditional Chinese and western medicine compound medicine for treating the rheumatoid bone disease.
Example 3:
(1) weighing 7 parts of liquorice, 3.5 parts of pseudo-ginseng, 4.5 parts of gentiana macrophylla and 7 parts of astragalus membranaceus, cleaning, airing and crushing to 1mm granularity to obtain raw material medicine particles A, mixing and decocting the raw material medicine particles A with 9 times of purified water for 3.5 hours, centrifuging for 10min at the rotating speed of 4000r/min, and separating to obtain a precipitate B and a supernatant C; mixing the precipitate B with 6 times of purified water, decocting for 2.5h, centrifuging at 5000r/min for 12min, and separating to obtain precipitate D and supernatant E; mixing the supernatant C and E, and vacuum concentrating under steam pressure of 0.18MPa, vacuum degree of 800mmhg, and temperature of 76 deg.C to obtain Chinese medicinal extract F with density of 1.05g/cm3；
(2) Weighing 5.5 parts of zaocys dhumnade, 3.5 parts of safflower, 0.25 part of ibuprofen, 0.15 part of calcium gluconate and 0.35 part of aluminum hydroxide, mixing, crushing, and sieving with a 100-mesh sieve to obtain raw material medicine powder G with the particle size less than 100 meshes;
(3) and uniformly mixing the traditional Chinese medicine extract F and the bulk drug powder G, and directly preparing pills of 5-7G/pill to obtain the traditional Chinese and western medicine compound medicine for treating the rheumatoid bone diseases.
Example 4:
(1) weighing 7 parts of liquorice, 3.5 parts of pseudo-ginseng, 4.5 parts of gentiana macrophylla and 7 parts of astragalus membranaceus, cleaning, airing and crushing to 1mm granularity to obtain raw material medicine particles A, mixing and decocting the raw material medicine particles A with 9 times of purified water for 3.5 hours, centrifuging for 10min at the rotating speed of 4000r/min, and separating to obtain a precipitate B and a supernatant C; mixing the precipitate B with 6 times of purified water, decocting for 2.5h, centrifuging at 5000r/min for 12min, and separating to obtain precipitate D and supernatant E; mixing the supernatant C and E, and vacuum concentrating under steam pressure of 0.18MPa, vacuum degree of 800mmhg, and temperature of 76 deg.C to obtain Chinese medicinal extract F with density of 1.05g/cm3；
(2) Weighing 5.5 parts of zaocys dhumnade, 3.5 parts of safflower, 0.25 part of ibuprofen, 0.3 part of calcium gluconate and 0.35 part of aluminum hydroxide, mixing, crushing, and sieving with a 100-mesh sieve to obtain raw material medicine powder G with the particle size less than 100 meshes;
(3) and uniformly mixing the traditional Chinese medicine extract F and the bulk drug powder G, preparing into particles with the particle size of 14-60 meshes, and bagging according to the specification of 6G per bag to obtain the traditional Chinese and western medicine compound medicine for treating the rheumatoid bone disease.
Example 5:
(1) weighing 10 parts of liquorice, 8 parts of pseudo-ginseng, 5 parts of gentiana macrophylla and 10 parts of astragalus membranaceus, cleaning, airing, and crushing to 1mm granularity to obtain raw material medicine particles A, mixing and decocting the raw material medicine particles A with 9 times of purified water for 3.5 hours, centrifuging for 10min at the rotating speed of 4000r/min, and separating to obtain a precipitate B and a supernatant C; mixing the precipitate B with 6 times of purified water, decocting for 2.5h, centrifuging at 5000r/min for 12min, and separating to obtain precipitate D and supernatant E; mixing the supernatant C and E at steam pressure of 0.18MPa, vacuum degree of 800mmhg and temperature of 76 deg.CUnder the condition, vacuum decompression concentration is adopted to obtain a traditional Chinese medicine extract F, and the density of the traditional Chinese medicine extract F is 1.05g/cm3；
(2) Weighing 8 parts of zaocys dhumnade, 4 parts of safflower, 0.3 part of ibuprofen, 0.25 part of calcium gluconate and 0.2 part of aluminum hydroxide, mixing, crushing, and sieving with a 100-mesh sieve to obtain bulk drug powder G with the particle size of less than 100 meshes;
(3) and uniformly mixing the traditional Chinese medicine extract F and the bulk drug powder G, preparing into particles with the particle size of 14-60 meshes, and bagging according to the specification of 6G per bag to obtain the traditional Chinese and western medicine compound medicine for treating the rheumatoid bone disease.
Example 6:
(1) weighing 3 parts of liquorice, 1 part of pseudo-ginseng, 2 parts of gentiana macrophylla and 6 parts of astragalus mongholicus, cleaning, airing and crushing to 1mm of granularity to obtain raw material medicine particles A, mixing and decocting the raw material medicine particles A and 9 times of purified water for 3.5 hours, centrifuging for 10min at the rotating speed of 4000r/min, and separating to obtain a precipitate B and a supernatant C; mixing the precipitate B with 6 times of purified water, decocting for 2.5h, centrifuging at 5000r/min for 12min, and separating to obtain precipitate D and supernatant E; mixing the supernatant C and E, and vacuum concentrating under steam pressure of 0.18MPa, vacuum degree of 800mmhg, and temperature of 76 deg.C to obtain Chinese medicinal extract F with density of 1.05g/cm3；
(2) Weighing 4 parts of zaocys dhumnade, 3 parts of safflower, 0.15 part of ibuprofen, 0.2 part of calcium gluconate and 0.1 part of aluminum hydroxide, mixing, crushing, and sieving with a 100-mesh sieve to obtain bulk drug powder G with the particle size of less than 100 meshes;
(3) and uniformly mixing the traditional Chinese medicine extract F and the bulk drug powder G, preparing into particles with the particle size of 14-60 meshes, and bagging according to the specification of 6G per bag to obtain the traditional Chinese and western medicine compound medicine for treating the rheumatoid bone disease.
The method for taking the Chinese and western medicine compound medicine for treating the rheumatoid bone disease is to take the Chinese and western medicine compound medicine twice a day and 12g of the compound medicine for each time, namely, two pills of 6 g/bag of medicine and 2 bags or 6 g/pill of medicine are taken, and the Chinese and western medicine compound medicine is taken orally half an hour after breakfast and supper.
Clinical cases
In order to show the treatment effect of the traditional Chinese and western medicine compound medicine for treating the rheumatic bone disease, 325 cases are clinically observed, wherein 172 men and 153 women are cured by 25-83 years old and 15-27 days of the course of disease and 309 men are cured, the cure rate reaches 95.08%, and the effective rate reaches 100%.
Wangzhi, women, age 38, history of rheumatoid arthritis for 15 days, slight edema of ankle and face, red and swollen joint of thumb and thumb of right hand and slight pain, the compound Chinese and Western medicine for treating the rheumatoid bone disease prepared in the embodiment 2 is used for treatment, the joint swelling and pain disappear after 3 days, the disease heals after 5 days, and no relapse occurs after one year of follow-up diagnosis.
Zhangzhi, male, 25 years old, the history of rheumatoid arthritis is 3 months, the legs usually feel ache, the knees are drilled into the knee like cold wind in cold weather or rainy days, the pain is strong, the compound Chinese and western medicine for treating the rheumatoid bone disease prepared in the embodiment 1 is used for treating, the ache and the pain disappear after 5 days, the disease is healed after 1 month, and the disease does not relapse in cold weather or rainy days after one year of diagnosis.
In case of a certain disease of Qinzhi, women and 52 years old, the history of rheumatoid arthritis is 2 years old, the symptoms of osteoporosis are accompanied, the joints are often swollen, the fingers are not stretched directly, and the pain is difficult to be suffered, the compound Chinese and western medicine for treating the rheumatoid bone disease prepared in the embodiment 4 is used for treatment, the pain is difficult to be suffered to disappear after 7 days, the disease is healed after 3 months, and the disease is not relapsed after one year of follow-up diagnosis.
Wangzhi, male, 78 years old, the rheumatism history is more than 5 years old, accompanied with osteoporosis symptoms, and some treatments such as traditional Chinese medicine, western medicine, acupuncture and moxibustion and the like have been adopted all the time, so that the joint is controlled not to deform, but the joint is red, swollen and painful after the relapse in spring festival every year, the Chinese and western medicine compound medicine for treating the rheumatism bone disease prepared in the embodiment 4 is used for treating, the joint swelling and pain are relieved after 3 days, the joint swelling and pain disappear after 10 days, the disease is healed after 5 months, and the disease does not relapse after two years of follow-up diagnosis.
The compound Chinese and western medicine for treating the rheumatic bone disease prepared in the example 5 is used for treating the Chua's disease, male and male with 51 years old, the rheumatism history is 10 years, the left elbow joint is seriously changed, the knee joints of both legs are just slightly deformed, red, swollen and painful, and the disease is frequently bedridden, so that the joint swelling and pain are relieved after 5 days, the pain disappears after 20 days, the disease is healed after 14 months, and the disease is cured after one year without relapse.
When the compound Chinese and western medicine for treating the rheumatoid bone disease prepared in example 5 is used for treating a certain plum, a woman and a person of 62 years old with a rheumatoid disease history of 20 years, the spine is seriously deformed and painful, the height of the compound Chinese and western medicine for treating the rheumatoid bone disease is 165cm originally and is 155cm at present, the pain is obviously relieved after 7 days, the pain disappears after 1 month, the compound Chinese and western medicine is healed after 2 years, and the disease does not relapse after one year of follow-up diagnosis.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those skilled in the art that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (4)
1. A Chinese and western medicine compound medicine for treating rheumatoid bone diseases is composed of traditional Chinese medicine components and western medicine components, and is characterized in that the traditional Chinese medicine components are mainly prepared by extracting the following raw material medicines in parts by weight: 3-10 parts of liquorice, 2-8 parts of zaocys dhumnade, 1-4 parts of pseudo-ginseng, 2-5 parts of gentiana macrophylla, 5-10 parts of astragalus membranaceus and 2-4 parts of safflower, wherein the western medicine components are mainly prepared by mixing the following raw material medicines in parts by weight: 0.1-0.3 part of ibuprofen, 0.1-0.3 part of calcium gluconate and 0.2-0.5 part of aluminum hydroxide.
2. The compound traditional Chinese medicine and western medicine for treating the rheumatoid bone disease as claimed in claim 1, wherein the traditional Chinese medicine components are mainly prepared by extracting the following raw material medicines in parts by weight: 5-8 parts of liquorice, 4-6 parts of zaocys dhumnade, 2-3 parts of pseudo-ginseng, 3-4 parts of gentiana macrophylla, 7-9 parts of astragalus membranaceus and 3-4 parts of safflower, wherein the western medicine components are mainly prepared by mixing the following raw material medicines in parts by weight: 0.15-0.25 part of ibuprofen, 0.15-0.25 part of calcium gluconate and 0.3-0.4 part of aluminum hydroxide.
3. A preparation method of a Chinese and western medicine compound medicine for treating rheumatoid bone diseases is characterized by comprising the following steps:
(1) weighing the following raw material medicines in parts by weight: cleaning, air drying and pulverizing the raw material medicines of liquorice, pseudo-ginseng, gentiana macrophylla and astragalus membranaceusMixing the raw material medicine particles A with purified water 6-9 times the particle size of 1mm, decocting for 2-4h, centrifuging at 3000-5500r/min, and separating to obtain precipitate B and supernatant C; mixing the precipitate B with purified water 6-9 times the amount of the precipitate B, decocting for 2-3h, centrifuging at the rotating speed of 3000-5500r/min, and separating to obtain a precipitate D and a supernatant E; mixing the supernatant C and E, and vacuum concentrating under reduced pressure at steam pressure of 0.20MPa or less, vacuum degree of 710-800mmhg, and temperature of 60-79 deg.C to obtain Chinese medicinal extract F with density of 1.02-1.2g/cm3；
(2) Weighing the following raw material medicines in parts by weight: mixing Zaocys, Carthami flos, ibuprofen, calcium gluconate and aluminum hydroxide, pulverizing, and sieving with 100 mesh sieve to obtain crude drug powder G smaller than 100 mesh;
(3) mixing the Chinese medicinal extract F and the crude drug powder G uniformly, making into granules with particle size of 14-60 meshes, and bagging according to the specification of 5-7G per bag.
4. The preparation method of the compound traditional Chinese medicine and western medicine for treating the rheumatoid bone disease as claimed in claim 3, wherein the traditional Chinese medicine extract F in the step (3) is uniformly mixed with the bulk drug powder G, and is directly prepared into pills of 5-7G/pill.
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