CN112014518A - Multifunctional module combined liquid chromatographic system - Google Patents

Multifunctional module combined liquid chromatographic system Download PDF

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Publication number
CN112014518A
CN112014518A CN202010847827.1A CN202010847827A CN112014518A CN 112014518 A CN112014518 A CN 112014518A CN 202010847827 A CN202010847827 A CN 202010847827A CN 112014518 A CN112014518 A CN 112014518A
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China
Prior art keywords
buffering
column
limiting
block
buffer
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Withdrawn
Application number
CN202010847827.1A
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Chinese (zh)
Inventor
赵利新
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Nanjing Yunzhu Information Technology Co Ltd
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Nanjing Yunzhu Information Technology Co Ltd
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Priority to CN202010847827.1A priority Critical patent/CN112014518A/en
Publication of CN112014518A publication Critical patent/CN112014518A/en
Withdrawn legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

The invention discloses a multifunctional module combined liquid chromatography system which comprises an installation base and a chromatography body, wherein the chromatography body is arranged in the installation base, a fixed column is arranged in the installation base in a sliding manner and connected with a fixer, the two fixers jointly fix the chromatography body, and a driver is arranged in the installation base; the driver is used for driving the fixer. According to the invention, the handle is rotated, the rotating shaft rotates, the driving shaft rotates, the screw block screw blocks are in threaded connection with the positive thread area and the negative thread area, and then the two screw block screw blocks move oppositely, so that the fixed column is driven to move, and then the chromatographic body is fixed by the fixer; through thread bush downstream, drive the card post that blocks and the buckle joint that resets then, buffer spring compression in the joint can be to device structure protection then, and the cooperation through clamping mechanism can be spacing to the fixed column simultaneously, has improved chromatogram body installation stability.

Description

Multifunctional module combined liquid chromatographic system
Technical Field
The invention relates to the technical field of liquid chromatography, in particular to a multifunctional module combined type liquid chromatography system.
Background
Chromatography, also known as chromatography, is a high performance physical separation technique that is used in analytical chemistry in conjunction with appropriate detection means to produce chromatographic analysis, and is classified into Gas Chromatography (GC) and Liquid Chromatography (LC) because the mobile phase can be either gas or liquid. The stationary phase may be either a solid or a liquid coated on a solid, and thus gas chromatography and liquid chromatography may be classified into gas-liquid chromatography, gas-solid chromatography, liquid-solid chromatography, and liquid-liquid chromatography. The liquid chromatography system mainly comprises: buffer solution bottle, high-pressure infusion pump, sample injector, chromatographic column, detector, waste liquid bottle, etc. In the use process of the liquid chromatograph, the constant supply of stable flow plays an important role in relation to the stability of the whole instrument system, thereby influencing the accuracy and precision of the analysis and test results.
The liquid chromatograph body in the existing liquid chromatograph system is generally placed on a desktop for medical detection operation, and is poor in stability and not beneficial to the use of the liquid chromatograph.
Disclosure of Invention
The technical problem to be solved by the present invention is to overcome the disadvantages of the prior art and to provide a multifunctional module combined liquid chromatography system.
In order to solve the technical problems, the technical scheme of the invention is as follows:
a multifunctional module combined liquid chromatography system comprises a mounting base and a chromatography body, wherein the chromatography body is arranged in the mounting base, a fixing column is arranged in the mounting base in a sliding mode and connected with a fixer, the two fixers jointly fix the chromatography body, and a driver is arranged in the mounting base; the driver is used for driving the fixer; the driver comprises a driving cavity, a driving shaft is arranged in the driving cavity, a positive thread area and a negative thread area are arranged in the driving shaft, the positive thread area and the negative thread area are in threaded connection with screw block screw blocks, the two screw block screws are respectively connected with a fixed column, the driving shaft is connected with a rotating shaft, and the rotating shaft penetrates through the driving cavity and is connected with the handle; the inner bottom wall of the driving cavity is provided with a limiting groove, a limiting rod is arranged in the limiting groove in a sliding mode, the limiting rod is connected with a screw block, and the limiting groove is arranged in the region range of a positive thread region and a negative thread region; the installation base is provided with a drawing mechanism in a drawing mode, and the drawing mechanism is used for limiting the chromatographic body; the drawing mechanism comprises a drawing column, the drawing column is arranged on the installation base in a drawing mode, one end of the drawing column is connected with a drawing limiting block, the two drawing limiting blocks limit the chromatographic body jointly, the other end of the drawing column is connected with a drawing block, a handle is arranged on the drawing block, the drawing block is connected with the installation base through a drawing spring, and the drawing column is sleeved with the drawing block.
As a preferable embodiment of the multifunctional module combined liquid chromatography system of the present invention, wherein: the driving shaft is provided with a limiting main bevel gear, the limiting main bevel gear is meshed with a limiting slave bevel gear, the limiting slave bevel gear is connected with a positioner, and the positioner is arranged on the bottom wall in the driving cavity.
As a preferable embodiment of the multifunctional module combined liquid chromatography system of the present invention, wherein: the locator includes the location box, rotates in the location box and is equipped with the location axle, and location axle top is connected with spacing from bevel gear, and the bottom is equipped with the lift screw thread district, and lift screw thread district thread bush is connected, and the thread bush bottom is equipped with clamping mechanism, the thread bush both sides are equipped with the auxiliary rod, and the auxiliary rod sets up with the spacing slip of the auxiliary tank that the location box lateral wall was equipped with, the buckle that the diapire was equipped with in the location box, clamping mechanism and the spacing setting of buckle.
As a preferable embodiment of the multifunctional module combined liquid chromatography system of the present invention, wherein: the clamping mechanism comprises a clamping plate, an installation bayonet is arranged on the clamping plate, a buffer spring is arranged at the installation bayonet, a reset clamping column is arranged at the bottom end of the buffer spring, and the reset clamping column is clamped with the buckle.
As a preferable embodiment of the multifunctional module combined liquid chromatography system of the present invention, wherein: the fixer includes fixed box, and fixed box and fixed column installation set up, are equipped with fixed slide in the fixed box, and fixed slide slides in the spout of fixed box, and fixed slide moves the post with spacing and is connected, and spacing post that moves is connected with spacing movable block, and the common spacing chromatogram body of two spacing movable blocks, fixed slide are connected with buffer gear, and buffer gear sets up the diapire in fixed box.
As a preferable embodiment of the multifunctional module combined liquid chromatography system of the present invention, wherein: buffer gear includes the cushion socket, is equipped with the dashpot in the cushion socket, and it is equipped with the buffer block to slide in the dashpot, and the buffer block articulates there is the buffering down tube, and two buffering down tubes are articulated to be set up jointly with fixed slide, two the buffer block is connected through first buffer spring, the cushion socket is connected with buffering owner's post, and buffering owner's post passes the buffering movable plate, slides on the buffering movable plate and sets up, and the buffering movable plate buffering sets up in fixed box, buffering owner's post cover is equipped with second buffer spring, and second buffer spring one end is connected with the buffering movable plate, and the other end is connected with the cushion socket.
As a preferable embodiment of the multifunctional module combined liquid chromatography system of the present invention, wherein: the buffering main column is connected with the inner bottom wall of the fixed box through a main spring, and the buffering movable plate is connected with the inner bottom wall of the fixed box through a secondary spring.
As a preferable embodiment of the multifunctional module combined liquid chromatography system of the present invention, wherein: the rubber ball is arranged on the pulling block, the mounting base is provided with a mounting frame, the mounting frame is provided with a lock groove, and the rubber ball and the lock groove are arranged in a locking mode.
The invention has the beneficial effects that:
(1) according to the invention, the handle is rotated, the rotating shaft rotates, the driving shaft rotates, the screw block screw blocks are in threaded connection with the positive thread area and the negative thread area, and then the two screw block screw blocks move oppositely, so that the fixed column is driven to move, and then the chromatographic body is fixed by the fixer; through thread bush downstream, drive the card post that blocks and the buckle joint that resets then, buffer spring compression in the joint can be to device structure protection then, and the cooperation through clamping mechanism can be spacing to the fixed column simultaneously, has improved chromatogram body installation stability.
(2) According to the invention, the fixed box is driven to move by the movement of the fixed column, firstly, the two limiting movable blocks limit the chromatographic body together, meanwhile, through the reaction of the limiting movable columns, the fixed sliding plate slides in the sliding groove of the fixed box, the buffer blocks are driven to slide in the buffer groove by the buffer inclined rods, the first buffer spring is compressed, the buffer base drives the buffer main column to move, then the second buffer spring is compressed, the main column and the buffer movable plate are simultaneously buffered to move, then the main spring and the auxiliary spring are driven to compress, thus the buffer effect is achieved, and then the effect of protection is achieved in the clamping and fixing chromatographic body.
(3) According to the invention, the two drawing limiting blocks limit the chromatographic body together, the handle is pulled, the drawing column moves away from one side of the chromatographic body, the spring is pulled to compress, and meanwhile, the drawing limiting blocks are positioned through the arrangement of the rubber ball and the lock groove lock catch, so that the fixation of the chromatographic body is released.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive exercise.
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic structural diagram of the actuator of the present invention;
FIG. 3 is a schematic view of the positioner of the present invention;
FIG. 4 is a schematic view of the fastener of the present invention;
FIG. 5 is an enlarged schematic view of the structure of FIG. 4 at A according to the present invention.
Detailed Description
In order that the present invention may be more readily and clearly understood, a more particular description of the invention briefly described above will be rendered by reference to specific embodiments that are illustrated in the appended drawings.
Referring to fig. 1-2, in the embodiment of the present invention, a multifunctional module combined liquid chromatography system includes a mounting base 1 and a chromatography body 2, where the chromatography body 2 is disposed in the mounting base 1, a fixing column 3 is slidably disposed in the mounting base 1, the fixing column 3 is connected to a fixer 4, the two fixers 4 fix the chromatography body 2 together, and a driver 5 is disposed in the mounting base 1; the driver 5 is used for driving the holder 4;
the driver 5 comprises a driving cavity 51, a driving shaft 52 is arranged in the driving cavity 51, a positive thread area 53 and a negative thread area 54 are arranged in the driving shaft 52, the positive thread area 53 and the negative thread area 54 are in threaded connection with screw block screw blocks 55, the two screw block screws 55 are respectively connected with a fixed column 3, the driving shaft 52 is connected with a rotating shaft 56, and the rotating shaft 56 penetrates through the driving cavity 51 to be connected with a handle 57; a limiting groove 58 is formed in the inner bottom wall of the driving cavity 51, a limiting rod 59 is arranged in the limiting groove 58 in a sliding mode, the limiting rod 59 is connected with the screw block 55, and the limiting groove 58 is formed in the area range of the positive thread area 53 and the negative thread area 54;
the handle 57 is rotated, the rotating shaft 56 rotates, the driving shaft 52 rotates, the positive thread area 53 and the negative thread area 54 are in threaded connection with the screw block screw blocks 55, and then the two screw block screw blocks 55 move oppositely, so that the fixing column 3 is driven to move, and then the fixing device 4 fixes the chromatographic body 2; the movement stability of the screw block and wire block 55 is improved by the matching of the limiting rod 59 which is arranged in the limiting groove 58 in a sliding way;
the installation base 1 is provided with a drawing mechanism 6 in a drawing way, and the drawing mechanism 6 is used for limiting the chromatographic body 2; the drawing mechanism 6 comprises a drawing column 61, the drawing column 61 is arranged on the installation base 1 in a drawing mode, one end of the drawing column 61 is connected with a drawing limiting block 62, the two drawing limiting blocks 62 limit the chromatographic body 2 jointly, the other end of the drawing column 61 is connected with a drawing block 63, a handle 64 is arranged on the drawing block 63, the drawing block 63 is connected with the installation base 1 through a drawing spring 65, and the drawing column 61 is sleeved with the drawing block 63.
The driving shaft 52 of the embodiment is provided with a limiting main bevel gear 7, the limiting main bevel gear 7 is meshed with a limiting auxiliary bevel gear 8, the limiting auxiliary bevel gear 8 is connected with a positioner 9, and the positioner 9 is arranged on the inner bottom wall of the driving cavity 51.
Referring to fig. 3, the positioner 9 of this embodiment includes a positioning box 91, a positioning shaft 92 is rotatably disposed in the positioning box 91, the top end of the positioning shaft 92 is connected to the limiting slave bevel gear 8, the bottom end of the positioning shaft 92 is provided with a lifting threaded area 93, the lifting threaded area 93 is connected to a threaded sleeve 94, the bottom end of the threaded sleeve 94 is provided with a locking mechanism 95, two sides of the threaded sleeve 94 are provided with auxiliary rods 98, the auxiliary rods 98 are slidably disposed in a limiting manner in auxiliary grooves 96 formed in side walls of the positioning box 91, a buckle 97 is disposed on a bottom wall of the positioning box 91, and the locking mechanism 95 is disposed in a limiting.
The driving shaft 52 rotates to drive the limiting main bevel gear 7 to rotate, then the limiting auxiliary bevel gear 8 rotates, so that the positioning shaft 92 rotates, the lifting threaded area 93 is threaded with the threaded sleeve 94, then the threaded sleeve 94 can move downwards, and the moving stability of the threaded sleeve 94 can be improved through the matching of the auxiliary rod 98 and the auxiliary groove 96;
the locking mechanism 95 of this embodiment includes the card fixed plate 951, is equipped with installation bayonet 952 on the card fixed plate 951, and installation bayonet 952 is equipped with buffer spring 953, and buffer spring 953 bottom is equipped with the card post 954 that resets, resets card post 954 and buckle 97 joint.
Through thread bush 94 downstream, drive card 951 downstream, then reset card post 954 and buckle 97 joint, buffer spring 953 compression in the joint can be to device structure protection then, and the cooperation through card mechanism 95 simultaneously can be spacing to fixed column 3, has improved 2 installation stability of chromatogram body.
Referring to fig. 4-5, the fixing device 4 of the present embodiment includes a fixing box 41, the fixing box 41 is installed with a fixing column 3, a fixing sliding plate 42 is disposed in the fixing box 41, the fixing sliding plate 42 slides in a sliding slot 43 of the fixing box 41, the fixing sliding plate 42 is connected with a limiting moving column 44, the limiting moving column 44 is connected with a limiting moving block 45, the two limiting moving blocks 45 limit the chromatography body 2 together, the fixing sliding plate 42 is connected with a buffer mechanism 46, and the buffer mechanism 46 is disposed on an inner bottom wall of the fixing box 41.
The buffering mechanism 46 of this embodiment includes a buffering seat 461, a buffering groove 462 is provided in the buffering seat 461, a buffering block 463 is slidably provided in the buffering groove 462, the buffering block 463 is hinged to a buffering slanting rod 4610, two buffering slanting rods 4610 are hinged to the fixed sliding plate 42, two buffering blocks 463 are connected by a first buffering spring 467, the buffering seat 461 is connected with a buffering main column 464, the buffering main column 464 penetrates through a buffering movable plate 465 and is slidably provided on the buffering movable plate 465, the buffering movable plate 465 is buffered and provided in the fixed box 41, the buffering main column 464 is sleeved with a second buffering spring 466, one end of the second buffering spring 466 is connected with the buffering movable plate 465, and the other end of the second buffering spring 466 is connected with the buffering seat 461.
The damping main post 464 of this embodiment is connected to the inner bottom wall of the stationary box 41 by a main spring 468, and the damping movable plate 465 is connected to the inner bottom wall of the stationary box 41 by a sub spring 469.
The fixed column 3 moves to drive the fixed box 41 to move, firstly, the two limit moving blocks 45 limit the chromatographic body 2 together, meanwhile, through the reaction of the limit moving column 44, the fixed sliding plate 42 slides in the sliding groove 43 of the fixed box 41, the buffer block 463 is driven by the buffer inclined rod 4610 to slide in the buffer groove 462, the first buffer spring 467 compresses, the buffer seat 461 drives the buffer main column 464 to move, then the second buffer spring 466 compresses, meanwhile, the buffer main column 464 and the buffer moving plate 465 move, then the main spring 468 is driven, the slave spring 469 compresses, thereby playing a buffer effect, and then playing a protection effect in clamping the fixed chromatographic body 2.
Be equipped with rubber ball 10 on the pulling piece 63 of this embodiment, be equipped with mounting bracket 11 on the installation base 1, be equipped with locked groove 12 on the mounting bracket 11, rubber ball 10 and the setting of locked groove 12 hasp.
Through the common spacing chromatogram body 2 of two pull limiters 62, pulling handle 64, the removal is kept away from chromatogram body 2 one side to pull post 61, and pulling spring 65 compresses, thereby fixes a position pull limiters 62 through rubber ball 10 and keyway 12 hasp setting simultaneously, removes the fixed to chromatogram body 2.
The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
In addition to the above embodiments, the present invention may have other embodiments; all technical solutions formed by adopting equivalent substitutions or equivalent transformations fall within the protection scope of the claims of the present invention.

Claims (8)

1. A multifunctional module combined liquid chromatography system comprises a mounting base and a chromatography body, and is characterized in that the chromatography body is arranged in the mounting base, a fixing column is arranged in the mounting base in a sliding manner, the fixing column is connected with a fixer, the two fixers jointly fix the chromatography body, and a driver is arranged in the mounting base; the driver is used for driving the fixer;
the driver comprises a driving cavity, a driving shaft is arranged in the driving cavity, a positive thread area and a negative thread area are arranged in the driving shaft, the positive thread area and the negative thread area are in threaded connection with screw block screw blocks, the two screw block screws are respectively connected with a fixed column, the driving shaft is connected with a rotating shaft, and the rotating shaft penetrates through the driving cavity and is connected with the handle; the inner bottom wall of the driving cavity is provided with a limiting groove, a limiting rod is arranged in the limiting groove in a sliding mode, the limiting rod is connected with a screw block, and the limiting groove is arranged in the region range of a positive thread region and a negative thread region;
the installation base is provided with a drawing mechanism in a drawing mode, and the drawing mechanism is used for limiting the chromatographic body; the drawing mechanism comprises a drawing column, the drawing column is arranged on the installation base in a drawing mode, one end of the drawing column is connected with a drawing limiting block, the two drawing limiting blocks limit the chromatographic body jointly, the other end of the drawing column is connected with a drawing block, a handle is arranged on the drawing block, the drawing block is connected with the installation base through a drawing spring, and the drawing column is sleeved with the drawing block.
2. The multifunctional modular combined liquid chromatography system of claim 1, wherein: the driving shaft is provided with a limiting main bevel gear, the limiting main bevel gear is meshed with a limiting slave bevel gear, the limiting slave bevel gear is connected with a positioner, and the positioner is arranged on the bottom wall in the driving cavity.
3. The multifunctional modular combined liquid chromatography system of claim 2, wherein: the locator includes the location box, rotates in the location box and is equipped with the location axle, and location axle top is connected with spacing from bevel gear, and the bottom is equipped with the lift screw thread district, and lift screw thread district thread bush is connected, and the thread bush bottom is equipped with clamping mechanism, the thread bush both sides are equipped with the auxiliary rod, and the auxiliary rod sets up with the spacing slip of the auxiliary tank that the location box lateral wall was equipped with, the buckle that the diapire was equipped with in the location box, clamping mechanism and the spacing setting of buckle.
4. The multifunctional modular combined liquid chromatography system of claim 3, wherein: the clamping mechanism comprises a clamping plate, an installation bayonet is arranged on the clamping plate, a buffer spring is arranged at the installation bayonet, a reset clamping column is arranged at the bottom end of the buffer spring, and the reset clamping column is clamped with the buckle.
5. The multifunctional modular combined liquid chromatography system of claim 4, wherein: the fixer includes fixed box, and fixed box and fixed column installation set up, are equipped with fixed slide in the fixed box, and fixed slide slides in the spout of fixed box, and fixed slide moves the post with spacing and is connected, and spacing post that moves is connected with spacing movable block, and the common spacing chromatogram body of two spacing movable blocks, fixed slide are connected with buffer gear, and buffer gear sets up the diapire in fixed box.
6. The multifunctional modular combined liquid chromatography system of claim 5, wherein: buffer gear includes the cushion socket, is equipped with the dashpot in the cushion socket, and it is equipped with the buffer block to slide in the dashpot, and the buffer block articulates there is the buffering down tube, and two buffering down tubes are articulated to be set up jointly with fixed slide, two the buffer block is connected through first buffer spring, the cushion socket is connected with buffering owner's post, and buffering owner's post passes the buffering movable plate, slides on the buffering movable plate and sets up, and the buffering movable plate buffering sets up in fixed box, buffering owner's post cover is equipped with second buffer spring, and second buffer spring one end is connected with the buffering movable plate, and the other end is connected with the cushion socket.
7. The multifunctional modular combined liquid chromatography system of claim 6, wherein: the buffering main column is connected with the inner bottom wall of the fixed box through a main spring, and the buffering movable plate is connected with the inner bottom wall of the fixed box through a secondary spring.
8. The multifunctional modular combined liquid chromatography system of claim 1, wherein: the rubber ball is arranged on the pulling block, the mounting base is provided with a mounting frame, the mounting frame is provided with a lock groove, and the rubber ball and the lock groove are arranged in a locking mode.
CN202010847827.1A 2020-08-21 2020-08-21 Multifunctional module combined liquid chromatographic system Withdrawn CN112014518A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010847827.1A CN112014518A (en) 2020-08-21 2020-08-21 Multifunctional module combined liquid chromatographic system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010847827.1A CN112014518A (en) 2020-08-21 2020-08-21 Multifunctional module combined liquid chromatographic system

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Publication Number Publication Date
CN112014518A true CN112014518A (en) 2020-12-01

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CN202010847827.1A Withdrawn CN112014518A (en) 2020-08-21 2020-08-21 Multifunctional module combined liquid chromatographic system

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115355225A (en) * 2021-05-17 2022-11-18 扬州宇新管业有限公司 Portable pipe fitting connecting device
CN115747796A (en) * 2023-01-10 2023-03-07 岗春激光科技(江苏)有限公司 Air-borne-to-gravity powder feeding device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115355225A (en) * 2021-05-17 2022-11-18 扬州宇新管业有限公司 Portable pipe fitting connecting device
CN115747796A (en) * 2023-01-10 2023-03-07 岗春激光科技(江苏)有限公司 Air-borne-to-gravity powder feeding device

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Application publication date: 20201201