CN112006273A - Healthy fat-reducing meal replacement powder without generating ketone and preparation method thereof - Google Patents
Healthy fat-reducing meal replacement powder without generating ketone and preparation method thereof Download PDFInfo
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- CN112006273A CN112006273A CN202010506274.3A CN202010506274A CN112006273A CN 112006273 A CN112006273 A CN 112006273A CN 202010506274 A CN202010506274 A CN 202010506274A CN 112006273 A CN112006273 A CN 112006273A
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- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
- A23L7/198—Dry unshaped finely divided cereal products, not provided for in groups A23L7/117 - A23L7/196 and A23L29/00, e.g. meal, flour, powder, dried cereal creams or extracts
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/125—Casei
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/169—Plantarum
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/175—Rhamnosus
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/531—Lactis
Abstract
The invention discloses healthy fat-reducing meal replacement powder without ketone and a preparation method thereof; wherein, the healthy fat-reducing meal replacement powder without ketone generation comprises: in the meal replacement powder, the carbohydrate energy supply ratio is 17-25%, the protein energy supply ratio is 25-40%, the fat energy supply ratio is 25-38%, and the dietary fiber energy supply ratio is 13-20%, meal replacement powder nutritional balance makes the human body preferentially use fat as the energy source, can accurately regulate and control human metabolic pathway, avoids the production of ketone body to reach the purpose of healthy fat reduction. The formula of the invention obtains the medium-long carbon chain triglyceride with low partial glyceride content, the easily-brewed whole grain powder, the fruit powder and the nut powder through various creative technological innovations, has the dietary fiber proportion with the maximum synergistic effect, and is coupled with the prebiotics, the multifunctional mixed probiotics and the like, thereby leading various functional components to exert the best effect.
Description
Technical Field
The invention belongs to the technical field of functional foods, and particularly relates to healthy fat-reducing meal replacement powder without ketone and a preparation method thereof.
Background
Obesity is an important cause of chronic diseases such as cardiovascular and cerebrovascular diseases, cancer, diabetes and the like, and is listed as one of ten diseases threatening human health by the world health organization. According to the statistical mathematics of the world health organization, the number of overweight people is over 10 hundred million, 3 hundred million people are seriously obese, and the obesity proportion of developing countries is greatly increased. In China, according to the research results of nutrition and health conditions published by Ministry of health, Ministry of science and technology and the national statistical office, 2 hundred million people in 13 hundred million people in China are overweight, and particularly, the overweight of children is rapidly increased. Therefore, controlling body weight is a significant global problem. The currently recommended physical activity increase and total energy intake reduction are correct and effective intervention means, but the effect is slow, the compliance is insufficient, and the long-term adherence is difficult.
At present, the carbohydrate content of the Chinese diet is relatively high. A high carbohydrate diet tends to increase insulin secretion. Insulin is a key hormone that promotes anabolism and promotes fat storage. Insulin stores energy as fat isolated in adipose tissue, preventing the energy from being oxidatively utilized by metabolically active tissues, resulting in an intracellular starvation condition. Hunger sensation and appetite reactivity are enhanced, calorie intake is increased, and energy is balanced, so that obesity appears. Reducing insulin level, improving cardiovascular metabolism, and reducing body weight. It is generally believed that hyperinsulinemia is secondary to obesity, and indeed, hyperinsulinemia may be primary, arising from autonomic dysfunction. Obesity is also a leptin resistant state, where leptin signaling defects promote excessive caloric intake to maintain normal energy expenditure; insulin acts as an antagonist of endogenous leptin, sharing a central signaling pathway with leptin; inhibiting insulin can reduce leptin resistance, thereby reducing caloric intake and increasing autonomic activity. Hyperinsulinemia also interferes with dopamine clearance in the ventral tegmental area and nucleus accumbens, promoting already elevated food rewards. Hyperinsulinemia promotes weight gain by the following mechanisms: promoting energy entry into adipose tissue, interfering with leptin signaling, interfering with the resolution of the food hedonic response.
Hyperinsulinemia is a corollary to high carbohydrate intake, which inhibits the release of fatty acids into the blood in adipose tissue by increasing insulin secretion, anchors fat in adipose tissue, and introduces fat in the blood circulation into adipose tissue for storage. Metabolically active organ tissues such as heart, muscle, liver, decrease available fatty acid from blood circulation, starving these cells, resulting in decreased adaptive energy consumption and increased food intake. Reducing the ratio of carbohydrate to fat supply in the food, reducing insulin secretion, increasing fat mobilization in adipose tissue, and promoting oxidation of free fatty acids in blood circulation. Such changes in metabolic and endocrine environments are therefore expected to reduce the state of hunger in cells, reduce hunger sensation, increase body fat loss, increase energy expenditure. Another possible mechanism of low carbon diet to reduce body weight is that fat and protein increase satiety, reduce concomitant hypoglycemia, and further reduce hunger, reduce total food intake, and produce an active energy deficit. The 3 rd mechanism of low carbon diet is that low carbon diet will produce higher metabolic combustion than high carbon diet, burning 200-300 kcal in addition compared with high carbon diet of equal heat.
Average daily carbohydrate intake varies widely among ethnic groups, so it is difficult to have a common low carbon standard worldwide. Average carbohydrate intake of 45% or less (energy source) in most countries is significant low carbon diet since the body does not undergo any metabolic changes in many cases when the carbohydrate content is below 45%, so carbohydrates are so low that they can be metabolized, i.e. when fat is burned. Currently, the carbohydrates in the diet are divided into 4, etc., according to their proportion in the total energy intake: very low-carbon (VLC): the carbohydrate accounts for less than 10% of the total energy, namely the ketogenic diet; low-carbon (LC): the total energy proportion of carbohydrate is less than 26%; ③ medium-carbon (MC): the carbohydrate accounts for 26 to 44 percent of the total energy; high-carbon (HC): the total energy content of carbohydrates is equal to or greater than 45%. When the total energy proportion of carbohydrate in the diet is less than 26%, the functional mode of the body changes from depending on glucose to depending on fatty acid and ketone body.
The current popular ketogenic diet weight-reducing method belongs to very low-carbon diet, mainly uses fat to provide energy, and the fat content accounts for 70-75%. Fatty acids undergo a beta oxidation process in vivo to produce acetyl-CoA, which needs to be combined with oxaloacetate in order to enter the Krebs cycle for complete oxidation. In the ketogenic diet, due to the lack of carbohydrates, insufficient oxaloacetate is present in the body and a large proportion of acetyl-CoA is metabolized to ketone bodies. Ketone bodies contain 3 components: acetoacetate, beta-hydroxybutyrate, and acetone. In the human body, under the condition of hunger or ketogenic diet, fatty acid provides energy for muscle and other tissues, but it cannot enter brain, and ketone body produced by fatty acid and ketogenic amino acid in liver enter brain through transport carrier to provide other energy for it. Normally, blood ketone bodies are minimal, and if blood ketone bodies are too high and urine ketone bodies appear, patients with some diseases, especially stealth diseases, may have certain health or life risks. Although the weight loss effect of people who lose weight by ketogenic diet is good in the initial stage, the proportion of people who can keep the weight loss result is only 1 percent finally. Compliance is too poor, and there is only a short-term fat-reducing effect, making ketogenic diets less effective in weight management.
At present, related patents report meal replacement powder for losing weight and reducing fat, but the prior patent technology basically adopts the efficacy of one or more components to achieve the purpose of losing weight and reducing fat, and does not consider the problem from the regulation and control of the basic metabolism of a human body, so the achieved effect is not very ideal.
Disclosure of Invention
This section is for the purpose of summarizing some aspects of embodiments of the invention and to briefly introduce some preferred embodiments. In this section, as well as in the abstract and the title of the invention of this application, simplifications or omissions may be made to avoid obscuring the purpose of the section, the abstract and the title, and such simplifications or omissions are not intended to limit the scope of the invention.
The present invention has been made in view of the above-mentioned technical drawbacks.
Therefore, as one aspect of the invention, the invention overcomes the defects in the prior art and provides the healthy fat-reducing meal replacement powder without generating ketone and the preparation method thereof.
In order to solve the technical problems, the invention provides the following technical scheme: a non-ketogenic healthy fat-reducing meal replacement powder, wherein: in the meal replacement powder, the energy supply ratio of carbohydrate is 17-25%, the energy supply ratio of protein is 25-40%, the energy supply ratio of fat is 25-38%, and the energy supply ratio of dietary fiber is 13-20%, so that the meal replacement powder is balanced in nutrition, fat is preferentially taken as an energy source by a human body, the metabolic pathway of the human body can be accurately regulated, the generation of ketone bodies is avoided, and the purpose of health and fat reduction is achieved; the meal replacement powder comprises, by mass, 13.4-53.6% of protein, 8-16% of medium-long chain triglyceride fat, 15-32% of dietary fiber, 10-14% of whole grain powder, 6-10% of fruit powder, 6-12% of nut powder and 1.4-2.6% of an additive.
The preferable scheme of the healthy fat-reducing meal replacement powder without ketone generation is as follows: the content of medium-long chain triglyceride in the medium-long chain triglyceride fat is more than 30%, the content of partial glyceride is less than 1% of the grease, the content of saturated fatty acid is 25-40%, the content of n-6 polyunsaturated fatty acid is 20-40%, and the content of n-3 polyunsaturated fatty acid is 4-8%; the medium-long chain triglyceride fat is medium-long chain triglyceride with low content of partial glyceride obtained by enzyme catalytic reaction, is beneficial to promoting the digestion and metabolism of fatty acid, avoids fat accumulation and prolongs the shelf life of the product.
The preferable scheme of the healthy fat-reducing meal replacement powder without ketone generation is as follows: the protein in the meal replacement powder is derived from one or more of soybean protein isolate, whey protein, egg white protein, whole grain powder, fruit powder and nut powder, wherein the content of the soybean protein isolate is 8-12%, the content of the whey protein is 7-10%, the content of the egg white protein is 4-10%, the content of the whole grain powder provides 1-2%, the content of the fruit powder provides 0.3-0.6%, and the content of the nut powder provides 1.7-4.1%.
The preferable scheme of the healthy fat-reducing meal replacement powder without ketone generation is as follows: the carbohydrates in the meal replacement powder are derived from whole grain powder, fruit powder and nut powder, wherein the whole grain powder provides 7.5-11.5% of the carbohydrates, the fruit powder provides 4.5-8.5% of the carbohydrates, and the nut powder provides 1.0-1.85% of the carbohydrates.
The preferable scheme of the healthy fat-reducing meal replacement powder without ketone generation is as follows: the dietary fiber in the meal replacement powder is selected from one or more of konjac gum, xanthan gum, sodium alginate, whole grain powder, fruit powder and nut powder; wherein the konjac glucomannan content is 4-6%, the xanthan gum content is 4-6%, the sodium alginate content is 2-3%, the whole grain powder provides 0.6-0.8% of dietary fiber, the fruit powder provides 0.1-0.3% of dietary fiber, and the nut powder provides 0.5-1.5% of dietary fiber; by adding the enzyme-treated whole grain powder, fruit powder and nut powder, on one hand, the full dietary fiber, the polyphenol substances and the good flavor are provided for the product, and meanwhile, the full grain powder, the fruit powder and the nut powder have better brewing performance through the hydrolysis of the enzyme.
The preferable scheme of the healthy fat-reducing meal replacement powder without ketone generation is as follows: the fat in the meal replacement powder is derived from one or more of medium-long chain triglyceride fat powder, whole grain powder, fruit powder and nut powder, wherein the medium-long chain triglyceride fat powder provides fat with the amount of 4.5-12%, the whole grain powder provides fat with the amount of 0.3-0.45%, the fruit powder provides fat with the amount of 0.15-0.35%, and the nut powder provides fat with the amount of 2.5-5%.
The preferable scheme of the healthy fat-reducing meal replacement powder without ketone generation is as follows: the additive comprises probiotic powder beneficial to intestinal microecological balance, and the content of the probiotic powder is 2-3.5%; wherein the probiotics comprise one or more of bacillus coagulans BC01, lactobacillus plantarum PL15, lactobacillus casei CL05, bifidobacterium lactis NJ241 and lactobacillus rhamnosus NJ 551; the bacillus coagulans BC01 is in a spore state, has high survival rate after entering the intestinal tract, can rapidly germinate within 4-6 hours and is converted into the bacillus coagulans, oxygen in the intestinal tract is consumed firstly during the germination process, limited nutrient substances and living space are strived for with intestinal tract harmful flora, and various lactic acid and coagulans for inhibiting harmful bacteria are generated simultaneously.
The preferable scheme of the healthy fat-reducing meal replacement powder without ketone generation is as follows: essential amino acids, vitamins and minerals in the meal replacement powder all meet the requirement of human body, so that the nitrogen balance of the human body is achieved, wherein,
histidine is more than or equal to 564.5mg/100g, isoleucine is more than or equal to 1191.0mg/100g, leucine is more than or equal to 2194.4mg/100g, lysine is more than or equal to 1815.3mg/100g, sulfur-containing amino acid (methionine and cysteine) is more than or equal to 893.6mg/100g, aromatic amino acid (tyrosine and phenylalanine) is more than or equal to 2066.8mg/100g, threonine is more than or equal to 998.9mg/100g, tryptophan is more than or equal to 989.9mg/100g, and valine is more than or equal to 1280.8mg/100 g;
the content of VA is not more than 12mg/Kg, the content of VD is not more than 0.2mg/Kg, the content of VE is not more than 2.360g/Kg, the content of VK is not more than 0.32mg/Kg, the content of VB1 is not more than 5.6mg/Kg, the content of VB2 is not more than 5.6mg/Kg, the content of VB6 is not more than 240mg/Kg, the content of VB12 is not more than 9.6 mu g/Kg, the content of pantothenic acid is not more than 24mg/Kg, the content of folic acid is not more than 4mg/Kg, the content of nicotinic acid is not more than 60mg/Kg, the content of nicotinamide is not more than 1.240g/Kg, the content of choline is not more than 8.8g/Kg, the content of biotin is not more than 0.16mg/Kg, and the content of;
the calcium content is not more than 7.6g/Kg, the phosphorus content is not more than 13.2g/Kg, the potassium content is not more than 14.4g/Kg, the magnesium content is not more than 1.32g/Kg, the chlorine content is not more than 9.2g/Kg, the iron content is not more than 168mg/Kg, the iodine content is not more than 2.4mg/Kg, the zinc content is not more than 124mg/Kg, the selenium content is not more than 1.6mg/Kg, the copper content is not more than 28mg/Kg, the fluorine content is not more than 12mg/Kg, the chromium content is not more than 0.12mg/Kg, the manganese content is not more than 40mg/Kg, and the molybdenum content is not more than 2 mg/Kg.
In one aspect, the invention overcomes the deficiencies in the prior art by providing a medium and long carbon chain triglyceride having a low partial glyceride content,
the medium-long carbon chain triglyceride with low content of partial glyceride obtained by enzyme catalytic reaction is beneficial to promoting the digestion and metabolism of fatty acid, avoiding fat accumulation and prolonging the shelf life of the product; wherein the content of medium-long carbon chain triglyceride is more than 30%, and the content of partial glyceride is less than 1% of the grease;
the medium-long chain triglyceride of the low-part glyceride is prepared by carrying out ester exchange and deacidification on base oil, and the preparation process comprises the steps of adopting Novozym 435 lipase with the enzyme adding amount of 8-15% to carry out random ester exchange on the base oil to prepare medium-long chain triglyceride, wherein the reaction temperature is 30-80 ℃, the time is 3-5 h, and the stirring speed is 300-700 rpm, so as to obtain an intermediate product; adding Lipase G with the pH value of 6.0-7.0, mixing the intermediate product with Lipase G according to the proportion that 180-1600U of Lipase G is added into each liter of the intermediate product, fully stirring and reacting for 1-3h at the temperature of 30-80 ℃, hydrolyzing partial glyceride, carrying out high-speed centrifugal separation on oil and water solution, and carrying out molecular distillation on an enzymolysis product to remove fatty acid, so as to obtain medium-long carbon chain triglyceride with low partial glyceride content, wherein in the base material oil, the mass fraction is 25-35% of coconut oil, 8-20% of olive oil, 4-12% of linseed oil, 8-25% of sunflower seed oil and 20-50% of walnut oil;
in the medium-long chain triglyceride of the low-part glyceride, the content of saturated fatty acid is 2.5-4%, the energy supply ratio is 7-9.5%, the content of linoleic acid is 2.4-3.3%, the energy supply ratio is 5.9-8.2%, the content of linolenic acid is 0.6-0.75 g/100 g%, and the energy supply ratio is 1.75-1.95%. .
As one aspect of the present invention, the present invention overcomes the disadvantages of the prior art and provides a method for preparing medium-long carbon chain triglyceride powder with low partial glyceride content, which comprises, stirring and dissolving gum arabic; adding medium-long carbon chain triglyceride with low partial glyceride content and continuously stirring to form emulsion; homogenizing the emulsion, and then carrying out spray drying to obtain grease powder; the mass ratio of the medium-long carbon chain triglyceride with low partial glyceride content to the Arabic gum is 1: 1; the homogenization is carried out for 5min at 14000 r/min; the solvent for dissolving the Arabic gum is water with the temperature of 60 ℃.
The invention has the beneficial effects that:
the formula of the invention obtains the medium-long carbon chain triglyceride with low partial glyceride content, the easily-brewed whole grain powder, the fruit powder and the nut powder through various creative technological innovations, has the dietary fiber proportion with the maximum synergistic effect, and is coupled with the prebiotics, the multifunctional mixed probiotics and the like, thereby leading various functional components to exert the best effect.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with examples are described in detail below.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, but the present invention may be practiced in other ways than those specifically described and will be readily apparent to those of ordinary skill in the art without departing from the spirit of the present invention, and therefore the present invention is not limited to the specific embodiments disclosed below.
Furthermore, reference herein to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one implementation of the invention. The appearances of the phrase "in one embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments.
Example 1
Selection of Novozym 435 lipase is used for random ester exchange of compounded vegetable oil to prepare medium and long carbon chain triglyceride, and the reaction conditions include enzyme adding amount of 8-15% and reaction temperature of 60 deg.cThe time is 5h, and the lipase is recovered by high-speed centrifugal filtration. Lipase G (by Amano Enz)yme Inc. produced by Penicilium camemberti fermentation) is prepared into 3000-8000U/L aqueous solution, the pH value is adjusted to 6.0-7.0 by phosphate buffer solution, an enzyme reaction intermediate product and the aqueous solution of Lipase G are mixed according to the volume ratio of 10 (0.6-2), partial glyceride is fully stirred and reacted for 1-3 hours at the temperature of 40-50 ℃, and oil and the aqueous solution are separated by high-speed centrifugation. And (3) carrying out molecular distillation on an enzymolysis product obtained by hydrolysis of Lipase G to remove fatty acid, thus obtaining the medium-long carbon chain triglyceride with low partial glyceride content.
TABLE 1.1 compositional volume percent of the formulated vegetable oils (%)
Serial number | Coconut oil | Linseed oil | Walnut kernel oil | Olive oil | Sunflower seed oil |
1 | 35 | 10 | 15 | 40 | 0 |
2 | 20 | 2 | 25 | 53 | 0 |
3 | 45 | 13 | 20 | 22 | 0 |
4 | 20 | 4 | 24 | 32 | 20 |
5 | 25 | 6 | 50 | 9 | 10 |
6 | 35 | 10 | 20 | 20 | 15 |
TABLE 1.2 Process parameters for the enzymatic transesterification and hydrolysis of the compounded vegetable oils
TABLE 1.3 composition ratio of glycerides in transesterified fats (%)
Dissolving Arabic gum in 60 deg.C distilled water, magnetically stirring until it is fully dissolved, slowly adding the medium-long carbon chain triglyceride with low partial glyceride content, stirring to obtain emulsions with Arabic gum and medium-long carbon chain triglyceride content of 25%, homogenizing the emulsions in homogenizer at 14000r/min for 5min, and spray drying to obtain powdered oil with oil-Arabic gum ratio of 1: 1.
Table 1.4 fatty acid composition and energy supply ratio of powdered fat No. 4
Fatty acids | Formula oil | Fatty acid composition (%) | Energy supply ratio (% E) |
C4:0 | 0.0 | 0.07 | 0.03 |
C6:0 | 0.0 | 0.06 | 0.02 |
C8:0 | 1.1 | 1.14 | 0.40 |
C10:0 | 1.1 | 1.18 | 0.41 |
C12:0 | 9.5 | 9.18 | 3.21 |
C14:0 | 3.9 | 3.95 | 1.38 |
C16:0 | 8.2 | 8.26 | 2.89 |
C16:1 | 0.3 | 0.34 | 0.12 |
C17:0 | 0.0 | 0.05 | 0.02 |
C17:1 | 0.0 | 0.03 | 0.01 |
C18:0 | 3.0 | 3.23 | 1.13 |
C18:1 | 38.2 | 38.16 | 13.35 |
C18:2n-6 | 28.7 | 28.23 | 9.87 |
C18:3n-3 | 4.9 | 4.72 | 1.65 |
Saturated fatty acid | 27.0 | 27.1 | 9.5 |
Fatty acid composition and energy supply ratio of the powdered fat or oil obtained in No. 5 of Table 1.5
Table 1.6 fatty acid composition and energy supply ratio of powdered fat No. 6
Fatty acids | Formula oil | Fatty acid composition (%) | Energy supply ratio (% E) |
C4:0 | 0.0 | 0.32 | 0.07 |
C6:0 | 0.0 | 0.26 | 0.05 |
C8:0 | 2.0 | 1.99 | 0.41 |
C10:0 | 1.9 | 2.23 | 0.46 |
C12:0 | 16.7 | 15.07 | 3.10 |
C14:0 | 6.8 | 7.05 | 1.45 |
C16:0 | 8.2 | 9.04 | 1.86 |
C16:1 | 0.2 | 0.37 | 0.08 |
C17:0 | 0.0 | 0.05 | 0.01 |
C17:1 | 0.0 | 0.03 | 0.01 |
C18:0 | 3.0 | 3.72 | 0.77 |
C18:1 | 28.7 | 29.26 | 6.02 |
C18:2n-6 | 24.0 | 22.92 | 4.72 |
C18:3n-3 | 7.7 | 6.91 | 1.42 |
Saturated fatty acid | 38.7 | 39.7 | 8.2 |
After treatment, the energy supply ratio of the fatty acid of the powdered oil with the serial number of 1-6 meets the requirement of the dietary nutrient reference intake of Chinese residents, the energy supply ratio of saturated fatty acid is less than 10, the energy supply ratio of n-6 polyunsaturated fatty acid is 2.5-9.0%, and the energy supply ratio of n-3 polyunsaturated fatty acid is 0.5-2.0%.
Example 2
The basic formula of the embodiment comprises, by mass, 30 parts of protein (10 parts of each of isolated soy protein, whey protein and egg white protein), 10 parts of dietary fiber (prepared by compounding konjac gum, xanthan gum and sodium alginate, wherein the respective proportions are 40%, 40% and 20%), 20 parts of medium-long-chain fat powder obtained in the embodiment 1, 10 parts of whole grain powder, 10 parts of fruit powder, 10 parts of nut powder and 9 parts of additives (the mass ratio of the additives is soybean lecithin, L-arabinose, stachyose, probiotic powder, vitamins, minerals, sucralose and erythritol is 1: 0.5: 0.5: 2.5: 1: 3.5: 0.2: 0.8). And fully stirring and uniformly mixing all the weighed material powder.
Wherein, the components and the mixture ratio of the whole grain powder, the fruit powder and the nut powder are shown in the table 2.1.
The cereal flour, fruit flour and nut flour are prepared as follows:
removing impurities from grains, cleaning, transferring to shallow-groove container, performing germination accelerating culture at 30 deg.C while spraying distilled water to keep paddy wet, culturing until sprout length is 0.5-1mm, oven drying in 40 deg.C heat pump drying oven, removing rice hull with rice huller, pulverizing with pulverizer, and sieving with 60 mesh sieve. Weighing 40-50U/g of high-temperature alpha-amylase liquid, dissolving the high-temperature alpha-amylase liquid in distilled water accounting for 10-15% of the mass of the grain, and uniformly mixing the high-temperature alpha-amylase liquid with the sprouted grain raw material. Extruding and puffing the materials by a double-screw extruder, collecting an extruded sample after the materials are stably discharged, drying at the constant temperature of 55 ℃, crushing the dried sample and sieving by a 40-mesh sieve;
crushing the raw material of the shell-free nuts without impurities, adjusting the water content to 10-20%, adding 2.5-3.5% of mixed enzyme containing cellulase and protease, uniformly mixing, wherein the ratio of the two enzymes is 8:2, performing enzymolysis for 20-30 min, performing extrusion and expansion treatment on the material by a double-screw extruder, collecting an extruded sample after discharging is stable, drying at the constant temperature of 55 ℃, crushing the dried sample, and sieving by a 40-mesh sieve;
cleaning fruit raw materials, pulping, adding 0.2-0.3 g/kg of ascorbic acid to protect the color of the fruit juice, adding 2-3% of pectinase and cellulase inwards, uniformly mixing, carrying out enzymolysis for 15-20 min, and then carrying out vacuum freeze drying on the materials, wherein the drying conditions are as follows: the prefreezing temperature is-40 ℃, the vacuum degree is 10Pa, and the sublimation heating temperature is 50 ℃.
TABLE 2.1 formulation of the base materials and their chemical composition
Whole grain flour | Mass fraction/% | Fruit powder | Mass fraction/% | Nut flour | Mass fraction/% |
Brown rice | 30 | Apple (Malus pumila) | 30 | Peanut | 30 |
Black rice | 10 | Lichee | 20 | Walnut (walnut) | 10 |
Millet | 20 | Grape | 20 | Pine nut | 10 |
Highland barley | 10 | Mango (mango) | 20 | Almond | 30 |
Oat | 20 | Strawberry | 10 | Hazelnut | 20 |
Buckwheat (Fagopyrum esculentum Moench) | 10 |
Through detection, the component content of the meal replacement powder obtained in the embodiment and the energy ratio provided by the meal replacement powder are shown in table 2.2, and the content of essential amino acids, fatty acids, vitamins and minerals in the healthy fat-reducing meal replacement powder formula without ketone is detected, and the result is shown in tables 2.3-2.5. As can be seen from the table, the meal replacement powder of this example has a protein energy supply ratio of about 38.13%, a carbohydrate energy supply ratio of 18.78%, a dietary fiber energy supply ratio of 13.45%, and a fat energy supply ratio of 29.64%. The energy supply ratio of saturated fatty acid in the meal replacement powder is 9.36 percent, the energy supply ratio of C18:2n-6 and C18:3n-3 are 5.96 percent and 1.75 percent respectively, and the requirements of the reference intake of nutrient in the diet of Chinese residents (2013 edition) on the energy supply ratio of saturated fatty acid (< 10%) n-6 polyunsaturated fatty acid (2.5-9%) and n-3 polyunsaturated fatty acid (0.2-2%) are met.
TABLE 2.2 chemical composition and energy supply ratio of meal replacement powder
Protein | Carbohydrate compound | Dietary fiber | Fat | |
Example 2 | 5.37 | 17.43 | 2.94 | 4.21 |
Mass ratio/%) | 35.38 | 17.43 | 24.96 | 12.22 |
Energy ratio/%) | 38.13 | 18.78 | 13.45 | 29.64 |
TABLE 2.3 essential amino acid composition in non-ketogenic healthy fat-reducing meal replacement powders
TABLE 2.4 healthy fat-reducing meal replacement powder without ketone formation, fatty acid mass fraction, content and energy ratio
Mass fraction (%) | Content (g/100g material) | Energy ratio (%) | |
C8:0 | 1.31 | 0.16 | 0.39 |
C10:0 | 1.27 | 0.16 | 0.38 |
C12:0 | 10.93 | 1.34 | 3.24 |
C14:0 | 4.43 | 0.54 | 1.31 |
C16:0 | 8.83 | 1.08 | 2.62 |
C16:1 | 0.29 | 0.04 | 0.09 |
C18:0 | 4.83 | 0.59 | 1.43 |
C18:1 | 42.08 | 5.14 | 12.47 |
C18:2n-6 | 20.12 | 2.46 | 5.96 |
C18:3n-3 | 5.92 | 0.72 | 1.75 |
Saturated fatty acid | 31.59 | 3.86 | 9.36 |
TABLE 2.5 detection of vitamins and minerals in the healthy fat-reducing meal replacement powder without ketone
Example 3
The basic formula of the meal replacement powder comprises, by mass, 21 parts of protein (soybean protein isolate: whey protein: egg albumin ═ 8: 7: 6), 15 parts of dietary fiber (prepared by compounding konjac gum, xanthan gum and sodium alginate, the respective proportions are 40%, 40% and 20%, namely the proportions of the konjac gum, the xanthan gum and the sodium alginate in the meal replacement powder dietary fiber are 6%, 6% and 3%), 30 parts of medium-long-chain fat powder, 12 parts of whole grain powder, 6 parts of fruit powder, 6 parts of nut powder and additives (the mass ratios of the additives are soybean lecithin, L-arabinose, stachyose, probiotic powder, vitamins, minerals, sucralose and erythritol are 0.8: 0.8: 0.3: 2: 1.2: 4: 0.3: 0.6).
The components and proportions of the whole grain flour, fruit flour and nut flour are as follows in table 3.1:
TABLE 3.1 formulation of the base materials and their chemical composition
Whole grain flour | Mass fraction/% | Fruit powder | Mass fraction/% | Nut flour | Mass fraction/% |
Brown rice | 20 | Apple (Malus pumila) | 40 | Peanut | 20 |
Black rice | 20 | Lichee | 15 | Walnut (walnut) | 20 |
Millet | 10 | Grape | 15 | Pine nut | 30 |
Highland barley | 20 | Mango (mango) | 15 | Almond | 20 |
Oat | 10 | Strawberry | 15 | Hazelnut | 10 |
Buckwheat (Fagopyrum esculentum Moench) | 20 |
The meal replacement powder prepared by the embodiment can provide about 26% of protein energy supply ratio, 17% of carbohydrate energy supply ratio, 19% of dietary fiber energy supply ratio and 37% of fat energy supply, and simultaneously achieve the balance of amino acid and fatty acid of a human body (according with the reference intake of dietary nutrients of Chinese residents). The energy supply ratio of saturated fatty acid in the meal replacement powder is 9.22 percent, the energy supply ratio of C18:2n-6 and C18:3n-3 are 8.14 percent and 1.69 percent respectively, and the requirements of the reference intake of nutrient in the diet of Chinese residents (2013 edition) on the energy supply ratio of saturated fatty acid (< 10%) n-6 polyunsaturated fatty acid (2.5-9%) and n-3 polyunsaturated fatty acid (0.2-2%) are met. Essential amino acids, fatty acids, vitamins and minerals of the meal replacement powder of the embodiment are detected, and the results are shown in tables 3.3-3.5.
TABLE 3.2 chemical composition and energy supply ratio of meal replacement powder
TABLE 3.3 essential amino acid composition in meal powder
TABLE 3.4 Mass fraction, content and energy ratio of fatty acids in meal powder
Mass fraction (%) | Content (g/100g material) | Energy ratio (%) | |
C8:0 | 0.91 | 0.14 | 0.34 |
C10:0 | 0.89 | 0.13 | 0.33 |
C12:0 | 7.61 | 1.14 | 2.82 |
C14:0 | 3.09 | 0.46 | 1.14 |
C16:0 | 8.85 | 1.33 | 3.28 |
C16:1 | 0.40 | 0.06 | 0.15 |
C18:0 | 3.52 | 0.53 | 1.31 |
C18:1 | 48.22 | 7.25 | 17.88 |
C18:2n-6 | 21.96 | 3.30 | 8.14 |
C18:3n-3 | 4.56 | 0.69 | 1.69 |
Saturated fatty acid | 24.86 | 3.74 | 9.22 |
TABLE 3.5 composition of vitamins and minerals in meal powder
Vitamin preparation | Content (mg/Kg) | Mineral substance | Content (mg/Kg) |
VA | 12.1 | Calcium carbonate | 7169 |
VD | 0.22 | Phosphorus (P) | 10788 |
VE | 1650 | Potassium salt | 11197 |
VK | 0.30 | Magnesium alloy | 1269 |
VB1 | 5.7 | Chlorine | 9188 |
VB2 | 5.6 | Iron | 170 |
VB6 | 203 | Iodine | 2.2 |
VB12 | 9.9(μg/Kg) | Zinc | 80.5 |
Pantothenic acid | 16.5 | Selenium | 1.4 |
Folic acid | 2.4 | Copper (Cu) | 24 |
Nicotinic acid | 60.7 | Fluorine | 10.5 |
Nicotinamide | 1233 | Chromium (III) | 0.13 |
Choline | 4789 | Manganese oxide | 26 |
Biotin | 0.16 | Molybdenum (Mo) | 2.1 |
Example 4
The basic formula of the instant embodiment is that, by mass, 25 parts of protein (isolated soy protein: whey protein: egg albumin ═ 12:9:4), 13 parts of dietary fiber (prepared by compounding konjac gum, xanthan gum and sodium alginate, the respective proportions are 40%, 40% and 20%, namely the proportions of konjac gum, xanthan gum and sodium alginate in the meal replacement powder dry dietary fiber are 5.2%, 5.2% and 2.6%), 12 parts of medium-long-chain fat powder in the serial number 3 in the example 1, 14 parts of whole grain powder, 10 parts of fruit powder, 12 parts of nut powder and 9 parts of additives (the mass ratio of each additive is that soybean lecithin: L-arabinose: stachyose: probiotic powder: vitamins: minerals: sucralose: erythritol ═ 1.5: 1.2: 3.5: 1.5: 4.5: 0.1: 0.5).
Wherein, the components and the mixture ratio of the whole grain powder, the fruit powder and the nut powder are as shown in the table 4.1:
TABLE 4.1 formulation of the base materials and their chemical composition
The meal replacement powder provided by the embodiment can provide about 35% of protein energy supply ratio, 24% of carbohydrate energy supply ratio, 13% of dietary fiber energy supply ratio and 26% of fat energy supply, and simultaneously achieves the balance of amino acid and fatty acid of a human body (according with the reference intake of dietary nutrients of Chinese residents). The energy supply ratio of saturated fatty acid in the meal replacement powder is 7.25%, the energy supply ratio of C18:2n-6 and C18:3n-3 are 6.62% and 1.93% respectively, and the requirements of the reference intake of dietary nutrients of Chinese residents (2013 edition) on the energy supply ratio of saturated fatty acid (< 10%) n-6 polyunsaturated fatty acid (2.5-9%) and n-3 polyunsaturated fatty acid (0.2-2%) are met.
TABLE 4.2 chemical composition and energy supply ratio of meal replacement powder
Protein | Carbohydrate compound | Dietary fiber | Fat | |
Example 4 | 6.19 | 20.99 | 3.34 | 5.48 |
Ratio of substances | 31.18 | 20.99 | 23.53 | 10.29 |
Energy ratio | 35.80 | 24.10 | 13.51 | 26.59 |
TABLE 4.3 essential amino acid composition in meal powder
TABLE 4.4 Mass fraction, content and energy ratio of fatty acids in meal powder
TABLE 4.5 composition of vitamins and minerals in meal powder
Vitamin preparation | Content (mg/Kg) | Mineral substance | Content (mg/Kg) |
VA | 8.1 | Calcium carbonate | 7580 |
VD | 0.3 | Phosphorus (P) | 13180 |
VE | 2345 | Potassium salt | 13500 |
VK | 0.30 | Magnesium alloy | 1180 |
VB1 | 5.2 | Chlorine | 9186 |
VB2 | 4.6 | Iron | 75 |
VB6 | 116 | Iodine | 0.43 |
VB12 | 9.3(μg/Kg) | Zinc | 29.8 |
Pantothenic acid | 19.7 | Selenium | 0.22 |
Folic acid | 4.1 | Copper (Cu) | 3.1 |
Nicotinic acid | 58 | Fluorine | 5.5 |
Nicotinamide | 1202 | Chromium (III) | 0.11 |
Choline | 8789 | Manganese oxide | 17.3 |
Biotin | 0.11 | Molybdenum (Mo) | 0.41 |
Vitamin C | 2356 |
Example 5:
and the sensory evaluation adopts a double-blind method to carry out scoring, each sample is repeated for three times, a sensory scoring standard is formulated according to the color, the flavor, the taste and the reconstitution property of the product, and the overall acceptance is used as an overall evaluation index. Sensory scoring criteria are shown in the table.
TABLE 5.1 sensory Scoring standards
TABLE 5.2 scoring profiles
Example 6: evaluation of human body experiment
The meal replacement powder of the embodiment 2-4 is subjected to human body experiments, 12 study subjects are obtained, 4 study subjects are obtained in each group, all the participating subjects are overweight (BMI is more than 24), diet intervention is carried out on the participating subjects, 250g is taken by each person every day, and human body composition tests are respectively carried out before intervention and at the end of the intervention.
TABLE 6.1 results of obesity-related index testing before and after intervention
According to the metabolic characteristics of a human body, based on the accurate limit of nutrient components, a fat-reducing meal replacement powder formula which is balanced in various macro and micro nutrients and can accurately regulate and control the basic metabolic pathway of the human body is designed, so that the human body preferentially takes fat as an energy source, and meanwhile, the generation of ketone bodies is avoided, and the purpose of health and fat reduction is achieved; the medium-long carbon chain triglyceride with low partial glyceride content obtained by enzyme catalysis reaction in the formula is a main fat source, which is beneficial to promoting the rapid digestion and metabolism of fatty acid, avoiding fat accumulation and prolonging the shelf life of the product; the whole grain powder, the fruit powder and the nut powder which are treated by enzyme are added, so that the product has better brewing performance while sufficient dietary fiber, polyphenol substances and good flavor are provided; by optimizing the proportion of the dietary fibers and utilizing the synergistic effect of the dietary fibers, the viscosity of the dietary fibers is increased, the postprandial glycemic index is stabilized, and the insulin resistance is relieved; prebiotics and multifunctional mixed probiotics are added in the formula, and the intestinal micro-ecological balance is maintained through the synergistic effect of the prebiotics and the multifunctional mixed probiotics. The meal replacement powder obtained by the invention has the advantages of high speed of reducing fat and blood sugar, obvious effect and no obvious side effect.
The formula of the optimized fat-reducing meal replacement powder disclosed by the invention enables a human body to preferentially use fat as an energy source after entering the human body, and simultaneously due to the existence of a proper amount of carbohydrate, the generation of ketone bodies can be well avoided by utilizing the intermediate metabolite of the carbohydrate, so that the purpose of health and fat reduction is achieved; the medium-long carbon chain triglyceride with low content of partial glyceride obtained by enzyme catalytic reaction is beneficial to promoting the digestion and metabolism of fatty acid, avoiding fat accumulation and prolonging the shelf life of the product; by adding the enzyme-treated whole grain powder, fruit powder and nut powder, on one hand, sufficient dietary fiber, polyphenol substances and good flavor are provided for the product, and meanwhile, the product has better brewing performance through the hydrolysis of enzyme; by optimizing the proportion of the dietary fibers and utilizing the synergistic effect of the dietary fibers, the viscosity of the dietary fibers is increased, the blood glucose load of the product is improved, the postprandial blood glucose index is stabilized, and the insulin resistance is relieved; prebiotics and probiotics are added in the formula, and the intestinal microecological balance is maintained through the synergistic effect of the prebiotics and the probiotics.
The meal replacement powder formula is added with probiotic powder which is beneficial to intestinal microecological balance, the content of the probiotic powder is 2-3.5%, the probiotic comprises bacillus coagulans BC01, lactobacillus plantarum PL15, lactobacillus casei CL05, bifidobacterium lactis NJ241 and lactobacillus rhamnosus NJ551, wherein the proportion of the bacillus coagulans BC01 is 10-20%, the proportion of the lactobacillus plantarum PL15 is 10-20%, the proportion of the lactobacillus casei CL05 is 10-30%, the proportion of the bifidobacterium lactis NJ241 is 10-30% and the proportion of the lactobacillus rhamnosus NJ551 is 20-30%; the bacillus coagulans BC01 is in a spore state, has high survival rate after entering the intestinal tract, can quickly germinate within 4-6 hours and is converted into the vegetative bacillus coagulans, oxygen in the intestinal tract is consumed during the germination process, limited nutrient substances and living space are strived for with harmful flora in the intestinal tract, and various lactic acid and coagulants for inhibiting the harmful bacteria are generated simultaneously; the lactobacillus plantarum PL15 is a facultative anaerobe, generates special lactobacillin, inhibits pathogenic bacteria, maintains intestinal balance and promotes nutrient absorption; the lactobacillus casei CL05 is resistant to gastric acid and bile salt, can be abundantly present in intestinal tract, regulates intestinal flora balance, prevents constipation and cell aging, and promotes digestion and absorption of human body; the bifidobacterium lactis NJ241 can inhibit the growth of putrefying bacteria in the intestinal tract by regulating the normal flora of the intestinal tract, thereby reducing the generation of some intestinal carcinogens and adsorbing carcinogenic and mutagenic substances in food, thereby protecting body cells from being damaged by the carcinogens; the Lactobacillus rhamnosus can enter human intestinal tract as living body, survive and colonize in human intestinal tract, promote growth of Bacillus bifidus and Lactobacillus acidophilus, balance and improve intestinal tract function, and prevent and treat diarrhea.
The stachyose added in the invention has very obvious proliferation effect on beneficial flora such as bifidobacterium, lactobacillus and the like in the gastrointestinal tract of a human body, can quickly improve the environment in the digestive tract of the human body and adjust the balance of microecological flora. The composition can promote the formation of dominant bacteria status of beneficial bacteria in the alimentary canal, inhibit the production of putrefying bacteria such as clostridium aerogen and acidogenic bacillus, and the like, and also generate a large amount of physiological active substances, adjust the pH value of the intestinal tract, kill pathogenic bacteria, inhibit the generation of putrefying products, inhibit the generation and absorption of endogenous carcinogens, and decompose and derive multiple immune function factors; the added L-arabinose can inhibit enzyme for hydrolyzing disaccharide, thereby inhibiting the rise of blood sugar caused by taking sucrose, simultaneously, the inhibition effect of the L-arabinose on the disaccharide hydrolase enables the sucrose which is not decomposed in small intestine to be decomposed by microorganisms in large intestine to generate a large amount of organic acid which has the inhibition effect on the synthesis of fat by liver, and the inhibition effect of the L-arabinose on the absorption of the sucrose in small intestine, thereby reducing the generation of new fat in vivo. The raw materials also comprise other food additives which influence the taste, flavor and texture of the meal replacement powder, and the food additives comprise 0.8 to 1.5 percent of soybean lecithin, 0.1 to 0.3 percent of sucralose and 0.5 to 0.8 percent of erythritol.
Therefore, the basic formula of the healthy fat-reducing meal replacement powder with low carbon water, high protein and high dietary fiber is optimized, and the accurate regulation and control on the human metabolism are realized: the fat is preferentially metabolized by a human body, meanwhile, the intermediate metabolite of carbohydrate is utilized, the generation of ketone bodies due to incomplete fat metabolism is avoided, the purpose of healthy fat reduction is achieved, the medium-long carbon chain triglyceride with low content of partial glyceride, the easily-brewed whole grain powder, the fruit powder and the nut powder are obtained through various creative technological innovations in the formula, the dietary fiber proportion with the maximum synergistic effect is realized, and the prebiotics, the multifunctional mixed probiotics and the like are coupled, so that various functional components play the best effect.
The balance of various nutrients is finally realized by optimizing the composition of various nutrient substances, so that amino acid, fatty acid, mineral substances, vitamins and the like all accord with the recommended standard of the reference intake of dietary nutrients of Chinese residents; the medium-long carbon chain triglyceride with low partial glyceride content obtained by adding enzyme reaction in the formula is beneficial to promoting the digestion and metabolism of fatty acid, avoiding fat accumulation and prolonging the shelf life of the product; the enzyme-treated whole grain powder, fruit powder and nut powder are added in the formula, so that the dietary fiber and the flavor of the product are improved, and the brewing performance of the product is better; the formula increases the viscosity of the dietary fiber by optimizing the proportion of the dietary fiber and utilizing the synergistic effect of the dietary fiber, improves the blood sugar load of the product, is beneficial to stabilizing the postprandial blood sugar index and relieving insulin resistance; meanwhile, prebiotics and probiotics are added in the formula, and the intestinal microecological balance is maintained through the synergistic effect of the prebiotics and the probiotics.
It should be noted that the above-mentioned embodiments are only for illustrating the technical solutions of the present invention and not for limiting, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, which should be covered by the claims of the present invention.
Claims (10)
1. A healthy fat-reducing meal replacement powder without generating ketone is characterized in that:
in the meal replacement powder, the energy supply ratio of carbohydrate is 17-25%, the energy supply ratio of protein is 25-40%, the energy supply ratio of fat is 25-38%, and the energy supply ratio of dietary fiber is 13-20%, so that the meal replacement powder is balanced in nutrition, fat is preferentially taken as an energy source by a human body, the metabolic pathway of the human body can be accurately regulated, the generation of ketone bodies is avoided, and the purpose of health and fat reduction is achieved;
the meal replacement powder comprises, by mass, 13.4-53.6% of protein, 8-16% of medium-long chain triglyceride fat, 15-32% of dietary fiber, 10-14% of whole grain powder, 6-10% of fruit powder, 6-12% of nut powder and 1.4-2.6% of an additive.
2. The non-ketogenic healthy fat-reducing meal replacement powder of claim 1, wherein: the content of medium-long chain triglyceride in the medium-long chain triglyceride fat is more than 30%, the content of partial glyceride is less than 1% of the grease, the content of saturated fatty acid is 25-40%, the content of n-6 polyunsaturated fatty acid is 20-40%, and the content of n-3 polyunsaturated fatty acid is 4-8%;
the medium-long chain triglyceride fat is medium-long chain triglyceride with low content of partial glyceride obtained by enzyme catalytic reaction, is beneficial to promoting the digestion and metabolism of fatty acid, avoids fat accumulation and prolongs the shelf life of the product.
3. The non-ketogenic healthy fat-reducing meal replacement powder of claim 1 or 2, wherein: the protein in the meal replacement powder is derived from one or more of soybean protein isolate, whey protein, egg white protein, whole grain powder, fruit powder and nut powder, wherein the content of the soybean protein isolate is 8-12%, the content of the whey protein is 7-10%, the content of the egg white protein is 4-10%, the content of the whole grain powder provides 1-2%, the content of the fruit powder provides 0.3-0.6%, and the content of the nut powder provides 1.7-4.1%.
4. The non-ketogenic healthy fat-reducing meal replacement powder of claim 1 or 2, wherein:
the carbohydrates in the meal replacement powder are derived from whole grain powder, fruit powder and nut powder, wherein the whole grain powder provides 7.5-11.5% of the carbohydrates, the fruit powder provides 4.5-8.5% of the carbohydrates, and the nut powder provides 1.0-1.85% of the carbohydrates.
5. The non-ketogenic healthy fat-reducing meal replacement powder of claim 1 or 2, wherein: the dietary fiber in the meal replacement powder is selected from one or more of konjac gum, xanthan gum, sodium alginate, whole grain powder, fruit powder and nut powder; wherein the konjac glucomannan content is 4-6%, the xanthan gum content is 4-6%, the sodium alginate content is 2-3%, the whole grain powder provides 0.6-0.8% of dietary fiber, the fruit powder provides 0.1-0.3% of dietary fiber, and the nut powder provides 0.5-1.5% of dietary fiber;
by adding the enzyme-treated whole grain powder, fruit powder and nut powder, on one hand, the full dietary fiber, the polyphenol substances and the good flavor are provided for the product, and meanwhile, the full grain powder, the fruit powder and the nut powder have better brewing performance through the hydrolysis of the enzyme.
6. The non-ketogenic healthy fat-reducing meal replacement powder of claim 1 or 2, wherein: the fat in the meal replacement powder is derived from one or more of medium-long chain triglyceride fat powder, whole grain powder, fruit powder and nut powder, wherein the medium-long chain triglyceride fat powder provides fat with the amount of 4.5-12%, the whole grain powder provides fat with the amount of 0.3-0.45%, the fruit powder provides fat with the amount of 0.15-0.35%, and the nut powder provides fat with the amount of 2.5-5%.
7. The non-ketogenic healthy fat-reducing meal replacement powder of claim 1 or 2, wherein: the additive comprises probiotic powder beneficial to intestinal microecological balance, and the content of the probiotic powder is 2-3.5%;
wherein the probiotics comprise one or more of bacillus coagulans BC01, lactobacillus plantarum PL15, lactobacillus casei CL05, bifidobacterium lactis NJ241 and lactobacillus rhamnosus NJ 551; the bacillus coagulans BC01 is in a spore state, has high survival rate after entering the intestinal tract, can rapidly germinate within 4-6 hours and is converted into the bacillus coagulans, oxygen in the intestinal tract is consumed firstly during the germination process, limited nutrient substances and living space are strived for with intestinal tract harmful flora, and various lactic acid and coagulans for inhibiting harmful bacteria are generated simultaneously.
8. The non-ketogenic healthy fat-reducing meal replacement powder according to any one of claims 1 to 7, wherein: essential amino acids, vitamins and minerals in the meal replacement powder all meet the requirement of human body, so that the nitrogen balance of the human body is achieved, wherein,
histidine is more than or equal to 564.5mg/100g, isoleucine is more than or equal to 1191.0mg/100g, leucine is more than or equal to 2194.4mg/100g, lysine is more than or equal to 1815.3mg/100g, sulfur-containing amino acid (methionine and cysteine) is more than or equal to 893.6mg/100g, aromatic amino acid (tyrosine and phenylalanine) is more than or equal to 2066.8mg/100g, threonine is more than or equal to 998.9mg/100g, tryptophan is more than or equal to 989.9mg/100g, and valine is more than or equal to 1280.8mg/100 g;
the content of VA is not more than 12mg/Kg, the content of VD is not more than 0.2mg/Kg, the content of VE is not more than 2.360g/Kg, the content of VK is not more than 0.32mg/Kg, the content of VB1 is not more than 5.6mg/Kg, the content of VB2 is not more than 5.6mg/Kg, the content of VB6 is not more than 240mg/Kg, the content of VB12 is not more than 9.6 mu g/Kg, the content of pantothenic acid is not more than 24mg/Kg, the content of folic acid is not more than 4mg/Kg, the content of nicotinic acid is not more than 60mg/Kg, the content of nicotinamide is not more than 1.240g/Kg, the content of choline is not more than 8.8g/Kg, the content of biotin is not more than 0.16mg/Kg, and the content of;
the calcium content is not more than 7.6g/Kg, the phosphorus content is not more than 13.2g/Kg, the potassium content is not more than 14.4g/Kg, the magnesium content is not more than 1.32g/Kg, the chlorine content is not more than 9.2g/Kg, the iron content is not more than 168mg/Kg, the iodine content is not more than 2.4mg/Kg, the zinc content is not more than 124mg/Kg, the selenium content is not more than 1.6mg/Kg, the copper content is not more than 28mg/Kg, the fluorine content is not more than 12mg/Kg, the chromium content is not more than 0.12mg/Kg, the manganese content is not more than 40mg/Kg, and the molybdenum content is not more than 2 mg/Kg.
9. A medium-long carbon chain triglyceride having a low partial glyceride content, characterized in that: the medium-long carbon chain triglyceride with low content of partial glyceride obtained by enzyme catalytic reaction is beneficial to promoting the digestion and metabolism of fatty acid, avoiding fat accumulation and prolonging the shelf life of the product; wherein the content of medium-long carbon chain triglyceride is more than 30%, and the content of partial glyceride is less than 1% of the grease;
the medium-long chain triglyceride of the low-part glyceride is prepared by performing ester exchange and deacidification on base oil,
carrying out random ester exchange on base oil by adopting Novozym 435 lipase with the enzyme adding amount of 8-15% to prepare medium-long carbon chain triglyceride, wherein the reaction temperature is 30-80 ℃, the reaction time is 3-5 h, and the stirring speed is 300-700 rpm, so as to obtain an intermediate product; adding Lipase G with the pH value of 6.0-7.0, mixing the intermediate product with Lipase G according to the proportion that 180-1600U of Lipase G is added into each liter of the intermediate product, fully stirring and reacting for 1-3h at the temperature of 30-80 ℃, hydrolyzing partial glyceride, carrying out high-speed centrifugal separation on oil and water solution, and carrying out molecular distillation on an enzymolysis product to remove fatty acid, thus obtaining medium-long carbon chain triglyceride with low content of partial glyceride;
according to the mass fraction, the base oil comprises 25-35% of coconut oil, 8-20% of olive oil, 4-12% of linseed oil, 8-25% of sunflower seed oil and 20-50% of walnut oil;
in the medium-long chain triglyceride of the low-part glyceride, the content of saturated fatty acid is 2.5-4%, the energy supply ratio is 7-9.5%, the content of linoleic acid is 2.4-3.3%, the energy supply ratio is 5.9-8.2%, the content of linolenic acid is 0.6-0.75 g/100 g%, and the energy supply ratio is 1.75-1.95%.
10. A process for the preparation of a low partial glyceride content medium-long carbon chain triglyceride powder according to claim 9, wherein:
stirring and dissolving the Arabic gum;
adding medium-long carbon chain triglyceride with low partial glyceride content and continuously stirring to form emulsion;
homogenizing the emulsion, and then carrying out spray drying to obtain grease powder; the mass ratio of the medium-long carbon chain triglyceride with low partial glyceride content to the Arabic gum is 1: 1; the homogenization is carried out for 5min at 14000 r/min; the solvent for dissolving the Arabic gum is water with the temperature of 60 ℃.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN114009786A (en) * | 2021-11-22 | 2022-02-08 | 江南大学 | Nutritional oil composition for vitamin D delivery, preparation method and application |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101115831A (en) * | 2005-01-19 | 2008-01-30 | 日清奥利友集团株式会社 | Method for producing a purified lipase |
CN103060086A (en) * | 2012-12-17 | 2013-04-24 | 华南理工大学 | Method for removing metaglyceride from grease |
CN103897811A (en) * | 2014-04-02 | 2014-07-02 | 河北康睿达脂质有限公司 | Production method for medium-chain and long-chain oil fatty acid |
US20150164840A1 (en) * | 2012-06-15 | 2015-06-18 | Vitaflo (International) Ltd | Nutritional product |
CN106418544A (en) * | 2016-06-30 | 2017-02-22 | 山东凤凰生物有限公司 | Protein and probiotic composite food with weight losing effect |
CN109645320A (en) * | 2019-02-28 | 2019-04-19 | 北京万莱康营养与健康食品科学技术研究院有限公司 | A kind of light jejunitas full nutrient formulation can brew instant stick and preparation method thereof |
-
2020
- 2020-06-05 CN CN202010506274.3A patent/CN112006273B/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101115831A (en) * | 2005-01-19 | 2008-01-30 | 日清奥利友集团株式会社 | Method for producing a purified lipase |
US20150164840A1 (en) * | 2012-06-15 | 2015-06-18 | Vitaflo (International) Ltd | Nutritional product |
CN103060086A (en) * | 2012-12-17 | 2013-04-24 | 华南理工大学 | Method for removing metaglyceride from grease |
CN103897811A (en) * | 2014-04-02 | 2014-07-02 | 河北康睿达脂质有限公司 | Production method for medium-chain and long-chain oil fatty acid |
CN106418544A (en) * | 2016-06-30 | 2017-02-22 | 山东凤凰生物有限公司 | Protein and probiotic composite food with weight losing effect |
CN109645320A (en) * | 2019-02-28 | 2019-04-19 | 北京万莱康营养与健康食品科学技术研究院有限公司 | A kind of light jejunitas full nutrient formulation can brew instant stick and preparation method thereof |
Non-Patent Citations (2)
Title |
---|
SAMEH A. KORMA,等: ""Preparation of structured lipids enriched withmedium- and long-chain triacylglycerols byenzymatic interesterification for infant formulaformula"", 《FOOD AND BIOPRODUCTS PROCESSING》 * |
周飞等: "中长碳链甘油三酯的研究进展", 《中国油脂》 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114009786A (en) * | 2021-11-22 | 2022-02-08 | 江南大学 | Nutritional oil composition for vitamin D delivery, preparation method and application |
CN114009786B (en) * | 2021-11-22 | 2023-04-07 | 江南大学 | Nutritional oil composition for vitamin D delivery, preparation method and application |
WO2024018421A1 (en) * | 2022-07-21 | 2024-01-25 | Biosfera Nature S.R.L. | Dietetic food product and method for the production thereof |
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