CN111999784B - Use of polymers as substrates for biochips - Google Patents
Use of polymers as substrates for biochips Download PDFInfo
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- CN111999784B CN111999784B CN202010930662.4A CN202010930662A CN111999784B CN 111999784 B CN111999784 B CN 111999784B CN 202010930662 A CN202010930662 A CN 202010930662A CN 111999784 B CN111999784 B CN 111999784B
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- optical waveguide
- pmma
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- 239000000758 substrate Substances 0.000 title claims abstract description 30
- 229920000642 polymer Polymers 0.000 title claims abstract description 25
- 238000000018 DNA microarray Methods 0.000 title claims abstract description 24
- 239000000463 material Substances 0.000 claims abstract description 24
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims abstract description 20
- 239000002861 polymer material Substances 0.000 claims abstract description 7
- 230000003287 optical effect Effects 0.000 claims description 31
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 17
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 17
- NRTOMJZYCJJWKI-UHFFFAOYSA-N Titanium nitride Chemical compound [Ti]#N NRTOMJZYCJJWKI-UHFFFAOYSA-N 0.000 claims description 9
- 239000000126 substance Substances 0.000 claims description 5
- 239000011521 glass Substances 0.000 abstract description 19
- 238000004519 manufacturing process Methods 0.000 abstract description 12
- 239000004417 polycarbonate Substances 0.000 description 9
- 229920000515 polycarbonate Polymers 0.000 description 9
- 239000004793 Polystyrene Substances 0.000 description 4
- 230000005284 excitation Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 238000000465 moulding Methods 0.000 description 3
- 229920002223 polystyrene Polymers 0.000 description 3
- 238000010146 3D printing Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 229920000307 polymer substrate Polymers 0.000 description 2
- 238000001338 self-assembly Methods 0.000 description 2
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000002086 nanomaterial Substances 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- -1 polydimethylsiloxane Polymers 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/045—Light guides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
- G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
- G02B6/122—Basic optical elements, e.g. light-guiding paths
- G02B6/1226—Basic optical elements, e.g. light-guiding paths involving surface plasmon interaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
- G02B6/10—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
- G02B6/12—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
- G02B2006/12035—Materials
- G02B2006/12069—Organic material
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optical Integrated Circuits (AREA)
Abstract
The invention discloses application of a polymer as a substrate of a local surface plasmon resonance biochip. The polymer material is used as the substrate of the local surface plasmon resonance biochip instead of the existing glass material, so that the manufacturing cost can be reduced, the structure is firm, the structure is easy to construct, the rapid forming is realized, and the requirement of large-scale manufacturing is met.
Description
Technical Field
The present invention relates to the field of biochips, in particular to the field of applications of polymers as substrates for localized surface plasmon resonance biochips.
Background
An advanced version based on nanotechnology, called Localized Surface Plasmon Resonance (LSPR) with nanostructures, is a technology that establishes label-free biosensing. The prior art biochip uses glass as a substrate, and has the disadvantages of high melting point, high-temperature process, hard and fragile structure, difficult shape change, complex manufacturing process, weak structure, difficult structure and difficult rapid molding.
Based on this, there is an urgent need in the art for an alternative substrate material for localized surface plasmon resonance biochips that can reduce cost, is structurally strong, is easy to construct, is rapidly shaped, and meets the needs of mass production.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention aims to: provided is an alternative substrate material for a localized surface plasmon resonance biochip, which can reduce manufacturing costs, has a strong structure, is easy to construct, is rapidly molded, and satisfies the need for mass production.
In order to achieve the above purpose, the technical scheme of the invention is as follows:
in one aspect, the invention provides the use of a polymer as a substrate for a localized surface plasmon resonance biochip.
In a preferred embodiment, the polymer is PMMA, PC or PS, more preferably PMMA or PC, most preferably PMMA.
In a preferred embodiment, the portions of the substrate may be composed of the same material or may be composed of different materials.
In a preferred embodiment, the localized surface plasmon resonance biochip further comprises: (1) A plurality of optical waveguides disposed in the substrate, the plurality of optical waveguides forming an optical waveguide array; (2) Titanium nitride nanocubes disposed on side surfaces of each of the optical waveguides.
In a preferred embodiment, the material of the optical waveguide is at least the same as the material of the base portion where the optical waveguide is provided, more preferably a PMMA or PC polymer material, most preferably a PMMA polymer material.
In a preferred embodiment, the titanium nitride nanocubes self-assemble on the surface of the optical waveguide array by chemical bonding.
The invention has the beneficial effects that:
1. the polymer material is used as the substrate of the local surface plasmon resonance biochip instead of the existing glass material, and has the advantages of low cost, firm structure, easy construction and rapid molding.
2. The polymer material is used as a substrate of the local surface plasmon resonance biochip, can be formed at one time through 3D printing, is convenient to manufacture and easy to form, and meets the requirement of large-scale manufacture.
3. The substrate and the optical waveguide adopt the same PMMA, PC and other polymers as constituent materials, not only can realize the refractive index basically the same as BK7 glass and the like, but also can be self-assembled and fixed on the surface of the polymer optical waveguide through chemical bonds with the titanium nitride nanocube material, thereby being convenient for manufacturing, improving the manufacturing efficiency and reducing the cost.
In conclusion, the technical scheme of the invention not only can reduce the manufacturing cost, has a firm structure, but also is easy to construct and rapidly mold, and meets the large-scale manufacturing requirement.
Drawings
The invention is described in further detail below with reference to the accompanying drawings and examples, it being noted that the examples or embodiments described below are intended to facilitate an understanding of the invention and are not limiting.
FIG. 1 shows a structure of a glass-based biochip of the prior art.
FIG. 2 shows one embodiment of the polymer of the present invention used as a localized surface plasmon resonance biochip.
Fig. 3 shows the arrangement of the titanium nitride nanocubes of the present invention on the side surface of a polymer optical waveguide.
FIG. 4 shows the real part (n) of the complex refractive index of a polymer compared to BK7 glass over the excitation light wavelength range of 400nm to 1200 nm.
Fig. 5 shows the imaginary part (k) of the complex refractive index of a polymer compared to BK7 glass in the excitation light wavelength range of 400nm to 1200 nm.
Detailed Description
As required, detailed embodiments of the present invention are disclosed herein. However, those skilled in the art will appreciate that the disclosed detailed embodiments are merely exemplary of the invention, which may be embodied in various and suitable forms. Therefore, specific structural and functional details disclosed herein are not to be interpreted as limiting, but as a basis for the claims and as a basis for teaching one skilled in the art to variously employ the present invention in virtually any appropriately detailed structure, structure or system.
Referring to fig. 1, a structure of a glass-based biochip according to the related art is shown. The prior art is a 40 nanometer gold island structure which takes glass as a substrate and grows by a high-temperature self-assembly tin shrinking method.
Referring to fig. 2, one embodiment of the polymer of the present invention used as a localized surface plasmon resonance biochip is shown. The polymer substrate for the localized surface plasmon resonance biochip of the present invention can be molded once by 3D printing. Those skilled in the art will appreciate that the substrate may be composed of one or more materials.
Referring to fig. 3, there is shown the arrangement of the titanium nitride nanocubes of the present invention on the side surface of a polymer optical waveguide. The optical waveguide shape and nanocube material shown in fig. 3 are for illustration only and not for limitation. It will be appreciated by those skilled in the art that the polymeric substrates of the present invention and the optical waveguides associated therewith may be of the same or different constituent materials, preferably at least the substrate portion where the optical waveguides are disposed and the optical waveguides are of the same material. It will be appreciated by those skilled in the art that either the polymeric optical waveguide or the substrate contains chemical bonds, and that the surface plasmon resonance portion of the optical waveguide may be dispersed and immobilized on the surface plasmon resonance sample detection portion of the optical waveguide by a chemical bond self-assembly method. For example, when a polymer such as PMMA, PC, or the like is used as a substrate and an optical waveguide, a titanium nitride nanocube is taken as an example of a surface plasmon resonance portion of the optical waveguide, and the titanium nitride nanocube may be self-assembled with the polymer optical waveguide by a titanyl bond and dispersed and fixed on the surface plasmon resonance sample detection portion of the optical waveguide.
Referring to FIG. 4, there is shown the real part (n) of the complex refractive index of a polymer compared to BK7 glass over the range of excitation light wavelengths from 400nm to 1200nm, n being an index of the propagation velocity of light waves in the dielectric, n being 1 in vacuum, a larger n representing a slower propagation velocity of light waves in the dielectric. In fig. 4, it is shown that polymethyl methacrylate (PMMA) is close to the n of BK7 glass, that the n of Polycarbonate (PC) and Polystyrene (PS) is higher than the n of BK7 glass, and that the n of polydimethylsiloxane is significantly smaller than the n of BK7 glass. In view of the fact that in localized plasmon surface plasmon resonance biochips, it is necessary to couple evanescent waves by total internal reflection to excite plasmon resonance, and bioanalytics detected by biochips typically contain water (n=1.3330), PMMA, PC and PS are preferred substrate materials instead of BK7 glass.
Referring to fig. 5, the imaginary part (k) of the complex refractive index of a polymer compared to BK7 glass over the range of excitation light wavelengths from 400nm to 1200nm is shown, k being an indicator of the loss of light through the material, the greater k, the greater the loss of light, and vice versa. In fig. 5, it is shown that k of PC and PMMA is approximately the same as k of BK7 glass, so PMMA, PC and PS are preferred base materials instead of BK7 glass. As can be confirmed from fig. 4 to 5, the polymer substrate of the present invention can achieve substantially the same refractive index as the BK7 glass substrate.
In conclusion, when the polymer provided by the invention is used as a substrate of a local surface plasmon resonance biochip, the refractive index of the polymer is the same as that of a glass substrate, and the polymer has the beneficial effects of low cost, easiness in construction, firm structure and rapid molding, and meets the requirement of large-scale manufacturing.
It is to be understood that although preferred embodiments have been described in detail hereinabove, the invention is not limited to the materials, structures and arrangements of features described and illustrated herein, which are merely exemplary preferred embodiments of the invention, which can be embodied in various equivalent forms.
Claims (9)
1. Use of a polymer as a substrate for a biochip, characterized in that the substrate is a substrate for a localized surface plasmon resonance biochip, wherein the biochip further comprises: (1) A plurality of optical waveguides disposed in the substrate, the plurality of optical waveguides forming an optical waveguide array; (2) Titanium nitride nanocubes disposed on side surfaces of each of the optical waveguides.
2. Use according to claim 1, characterized in that the polymer is PMMA, PC or PS.
3. Use according to claim 2, characterized in that the polymer is PMMA or PC.
4. Use according to claim 3, characterized in that the polymer is PMMA.
5. Use according to claim 1, characterized in that the parts of the substrate consist of the same material.
6. Use according to claim 1, characterized in that the parts of the substrate consist of different materials.
7. Use according to claim 1, characterized in that the material of the optical waveguide is at least the same as the material of the base part where the optical waveguide is provided, a PMMA or PC polymer material.
8. Use according to claim 7, characterized in that the material of the optical waveguide is at least the same as the material of the base part where the optical waveguide is arranged, a PMMA polymer material.
9. The use according to claim 1, wherein the titanium nitride nanocubes self-assemble on the surface of the optical waveguide array by chemical bonding.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010930662.4A CN111999784B (en) | 2020-09-07 | 2020-09-07 | Use of polymers as substrates for biochips |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010930662.4A CN111999784B (en) | 2020-09-07 | 2020-09-07 | Use of polymers as substrates for biochips |
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| Publication Number | Publication Date |
|---|---|
| CN111999784A CN111999784A (en) | 2020-11-27 |
| CN111999784B true CN111999784B (en) | 2024-03-22 |
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Citations (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005069978A (en) * | 2003-08-27 | 2005-03-17 | Toyobo Co Ltd | Biochip |
| CN101398377A (en) * | 2007-09-25 | 2009-04-01 | 北京大学 | Polymer SPR chip and method for making same |
| CN103868887A (en) * | 2014-03-11 | 2014-06-18 | 中国科学院重庆绿色智能技术研究院 | Graphene film-based tapered optical fiber sensor |
| CN104634763A (en) * | 2015-02-11 | 2015-05-20 | 浙江大学 | SPR sensor chip and preparation method thereof |
| EP3199993A1 (en) * | 2016-01-27 | 2017-08-02 | Centre National de la Recherche Scientifique (C.N.R.S.) | Optical plasmonic conductors comprising one or more fibrillar organic supramolecular species |
| KR20180028798A (en) * | 2016-09-09 | 2018-03-19 | 주식회사 엘지화학 | Glass light guide plate, backlight unit and display device including the same |
| CN107849738A (en) * | 2015-02-16 | 2018-03-27 | 密执安州立大学董事会 | System and method for carrying out immunoassays |
| CN109470682A (en) * | 2017-09-08 | 2019-03-15 | 清华大学 | Molecular vehicle for Molecular Detection |
| CN110087867A (en) * | 2016-12-19 | 2019-08-02 | 3M创新有限公司 | Flexible substrates and preparation method thereof with plasma particle surface covering |
| CN110662995A (en) * | 2017-01-20 | 2020-01-07 | 弗吉尼亚技术知识资产公司 | Plasmonic nanoparticle layers with controlled orientation |
| CN110764186A (en) * | 2018-07-27 | 2020-02-07 | 京东方科技集团股份有限公司 | Optical waveguide substrate and microfluidic device |
| WO2020065535A1 (en) * | 2018-09-24 | 2020-04-02 | Sabic Global Technologies B.V. | Integrated plasmons with thin film transistor (tft) device for molecular biosensing |
| CN111060466A (en) * | 2019-12-30 | 2020-04-24 | 暨南大学 | Portable optical gas sensor |
| US10725373B1 (en) * | 2016-10-21 | 2020-07-28 | Iowa State University Research Foundation, Inc. | Nano-patterning methods including: (1) patterning of nanophotonic structures at optical fiber tip for refractive index sensing and (2) plasmonic crystal incorporating graphene oxide gas sensor for detection of volatile organic compounds |
| CN112014924A (en) * | 2020-09-07 | 2020-12-01 | 科竟达生物科技有限公司 | Method for decorating nanocubes on surface of polymer optical waveguide, optical waveguide manufactured by method, biosensing system and application |
| CN112033932A (en) * | 2020-09-07 | 2020-12-04 | 科竟达生物科技有限公司 | Local surface plasmon resonance biochip, manufacturing method thereof, biosensing system comprising local surface plasmon resonance biochip and application of biosensing system |
| CN116953847A (en) * | 2023-08-02 | 2023-10-27 | 桂林电子科技大学 | Mixed surface plasma directional coupler for network on optical sheet |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7010182B2 (en) * | 2002-07-31 | 2006-03-07 | Luna Innovations Incorporated | Biosensors having enhanced environmental sensitivity |
| US10371892B2 (en) * | 2017-03-27 | 2019-08-06 | Board Of Regents, The University Of Texas System | Nanostructured photonic materials |
-
2020
- 2020-09-07 CN CN202010930662.4A patent/CN111999784B/en active Active
Patent Citations (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005069978A (en) * | 2003-08-27 | 2005-03-17 | Toyobo Co Ltd | Biochip |
| CN101398377A (en) * | 2007-09-25 | 2009-04-01 | 北京大学 | Polymer SPR chip and method for making same |
| CN103868887A (en) * | 2014-03-11 | 2014-06-18 | 中国科学院重庆绿色智能技术研究院 | Graphene film-based tapered optical fiber sensor |
| CN104634763A (en) * | 2015-02-11 | 2015-05-20 | 浙江大学 | SPR sensor chip and preparation method thereof |
| CN107849738A (en) * | 2015-02-16 | 2018-03-27 | 密执安州立大学董事会 | System and method for carrying out immunoassays |
| EP3199993A1 (en) * | 2016-01-27 | 2017-08-02 | Centre National de la Recherche Scientifique (C.N.R.S.) | Optical plasmonic conductors comprising one or more fibrillar organic supramolecular species |
| WO2017129776A1 (en) * | 2016-01-27 | 2017-08-03 | Centre National De La Recherche Scientifique | Optical plasmonic conductors comprising one or more fibrillar organic supramolecular species |
| KR20180028798A (en) * | 2016-09-09 | 2018-03-19 | 주식회사 엘지화학 | Glass light guide plate, backlight unit and display device including the same |
| US10725373B1 (en) * | 2016-10-21 | 2020-07-28 | Iowa State University Research Foundation, Inc. | Nano-patterning methods including: (1) patterning of nanophotonic structures at optical fiber tip for refractive index sensing and (2) plasmonic crystal incorporating graphene oxide gas sensor for detection of volatile organic compounds |
| CN110087867A (en) * | 2016-12-19 | 2019-08-02 | 3M创新有限公司 | Flexible substrates and preparation method thereof with plasma particle surface covering |
| CN110662995A (en) * | 2017-01-20 | 2020-01-07 | 弗吉尼亚技术知识资产公司 | Plasmonic nanoparticle layers with controlled orientation |
| CN109470682A (en) * | 2017-09-08 | 2019-03-15 | 清华大学 | Molecular vehicle for Molecular Detection |
| CN110764186A (en) * | 2018-07-27 | 2020-02-07 | 京东方科技集团股份有限公司 | Optical waveguide substrate and microfluidic device |
| WO2020065535A1 (en) * | 2018-09-24 | 2020-04-02 | Sabic Global Technologies B.V. | Integrated plasmons with thin film transistor (tft) device for molecular biosensing |
| CN111060466A (en) * | 2019-12-30 | 2020-04-24 | 暨南大学 | Portable optical gas sensor |
| CN112014924A (en) * | 2020-09-07 | 2020-12-01 | 科竟达生物科技有限公司 | Method for decorating nanocubes on surface of polymer optical waveguide, optical waveguide manufactured by method, biosensing system and application |
| CN112033932A (en) * | 2020-09-07 | 2020-12-04 | 科竟达生物科技有限公司 | Local surface plasmon resonance biochip, manufacturing method thereof, biosensing system comprising local surface plasmon resonance biochip and application of biosensing system |
| WO2022047848A1 (en) * | 2020-09-07 | 2022-03-10 | 科竟达生物科技有限公司 | Method for decorating nanocube on surface of optical waveguide of polymer, optical waveguide manufactured thereby, biosensing system, and application |
| WO2022047847A1 (en) * | 2020-09-07 | 2022-03-10 | 科竟达生物科技有限公司 | Local surface plasmon resonance biochip and manufacturing method therefor, biosensing system including same, and use of biosensing system |
| CN116953847A (en) * | 2023-08-02 | 2023-10-27 | 桂林电子科技大学 | Mixed surface plasma directional coupler for network on optical sheet |
Non-Patent Citations (6)
| Title |
|---|
| "聚合物光波导生物传感器的制备与特性研究";邹盼;《中国优秀硕士学位论文全文数据库 信息科技辑 (月刊)》(第7期);全文 * |
| Au/TiN复合薄膜制备及其表面增强拉曼光谱研究;吴振刚;刘燕梅;吴明明;陈颖;魏颖娜;羡皓晗;王学沛;魏恒勇;;光谱学与光谱分析(第02期);全文 * |
| Tempering Hemispherical Radiative Properties with a Resonance Compilation;Chen, Yu-Bin 等;《PLASMONICS 》;第10卷(第3期);全文 * |
| 基于氮化钛纳米球的等离子体模式与光热耦合性质的研究;窦杰;《万方数据知识服务平台》;全文 * |
| 基于氮化钛膜和金线的PCF-SPR传感特性研究;马颖;《中国优秀硕士学位论文全文数据库 信息科技辑 (月刊)》(10);全文 * |
| 自组装聚合物材料技术及其应用展望;华兰;冀克俭;邓卫华;刘元俊;邵鸿飞;;高分子材料科学与工程(第06期);全文 * |
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