CN111991502B - Traditional Chinese medicine compound vision plaster for treating ophthalmic diseases - Google Patents
Traditional Chinese medicine compound vision plaster for treating ophthalmic diseases Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
In order to solve the defects of the prior art, the invention provides a traditional Chinese medicine compound vision plaster for treating ophthalmic diseases, which comprises the following components: traditional Chinese medicine components, additives and a sticking film. The traditional Chinese medicine comprises the following components: semen plantaginis, herba Senecionis Scandentis, rhizoma anemarrhenae, semen Armeniacae amarum, and herba Taraxaci, wherein the total mass of semen plantaginis, herba Taraxaci and semen Armeniacae amarum is more than 60% of the total mass of the Chinese medicinal components. The weight parts of the plantain seed, the senecio scandens, the anemarrhena asphodeloides bunge, the almond and the dandelion are 15-30 parts, 5-10 parts of the senecio scandens, 2-5 parts of the rhizoma anemarrhenae and 15-25 parts of the almond. The traditional Chinese medicine compound vision plaster is obtained on the basis of traditional Chinese medicines, is convenient to use, has an obvious treatment effect on muscae volitantes, can obviously improve after being continuously used for about 10 days generally, and can not relapse within a long time after being continuously used for about 30-40 days.
Description
Technical Field
The invention belongs to the technical field of medicine, and particularly relates to a traditional Chinese medicine compound vision patch for treating ophthalmic diseases.
Background
The symptoms of muscae volitantes are: the patient may have dark spots in front of the eyes and fly away with the rotation of the eyeball, as if a mosquito is flying, and the shape of the mosquito is circular, oval, dot, linear, etc. It is often the case that a patient is more likely to find its presence when looking at a brighter background such as a blue sky, white walls, etc. The ophthalmic disease is generally caused by vitreous degeneration, a natural aging phenomenon, i.e., the vitreous "liquefies" with aging, producing some turbidity. Therefore, the formal name of the mosquito disease is "vitreous chaos" or "vitreous floating objects".
In the prior art, the treatment is generally carried out by supplementing antioxidant substances such as lutein, astaxanthin and the like, the treatment period is long, and the total treatment cost is higher.
Disclosure of Invention
The invention provides a traditional Chinese medicine compound vision plaster for treating ophthalmic diseases, aiming at the problems in the prior art, and the traditional Chinese medicine compound vision plaster comprises: traditional Chinese medicine components, additives and a sticking film. The traditional Chinese medicine comprises the following components: semen plantaginis, herba Senecionis Scandentis, rhizoma anemarrhenae, semen Armeniacae amarum, and herba Taraxaci, wherein the total mass of semen plantaginis, herba Taraxaci and semen Armeniacae amarum is more than 60% of the total mass of the Chinese medicinal components.
Furthermore, the plantain seed is 15-30 parts by mass, the groundsel is 5-10 parts by mass, the rhizoma anemarrhenae is 2-5 parts by mass, the almond is 20-25 parts by mass, and the dandelion is 15-20 parts by mass.
Further, the additives are: acrylamide and potassium persulfate. The film comprises: a viscose patch A for storing Chinese medicinal components and a smooth patch B for storing viscose patch A.
The compound eyesight patch is prepared by taking semen plantaginis, dandelion and almond as a component A and senecio scandens and rhizoma anemarrhenae as a component B, and the preparation method of the compound eyesight patch comprises the following steps:
s1, mixing the component A with 3-5 times of water by mass, and then carrying out decoction operation A.
S2, after the decoction operation A is finished, carrying out solid-liquid separation through filter cloth to obtain a solid-phase component A and a liquid-phase component A.
S3, mixing the liquid-phase component A with the component B, and then carrying out decoction operation B. And after the decoction operation B is finished, carrying out solid-liquid separation through filter cloth to obtain a solid-phase component B and a liquid-phase component B.
S4, crushing the solid phase component A to 80-120 meshes, and crushing the solid phase component B to 150-180 meshes. Then mixing the crushed products of the two to obtain a mixture. Baking the liquid phase component B at the temperature of 120 ℃ and 130 ℃ until the mass of the liquid phase component B is reduced by 70-75 percent to obtain a liquid phase component C.
S5, adding acrylamide accounting for 8-10% of the mass of the liquid phase component C into the liquid phase component C, and adding potassium persulfate accounting for 0.3-0.5% of the mass of the mixture into the mixture. Then mixing the two, and reacting for 5-10 minutes at 80-90 ℃ to obtain a paste.
S6, smearing paste at the set position of the patch A, flattening, and then covering the patch B on the patch A to obtain the traditional Chinese medicine compound vision patch for treating the ophthalmic diseases.
Further, the decoction operation A comprises the following steps: putting the mixture of the component A and water into a closed container to submerge the component A in the water. Then heating to 110-115 ℃ for decoction for 30-35 minutes.
Further, the decoction operation B comprises the following steps: putting the mixture of the liquid-phase component A and the component B into a closed container to enable the liquid-phase component A to submerge the component B. Then heating to 120-.
The invention has the advantages that: the traditional Chinese medicine compound vision plaster is obtained on the basis of traditional Chinese medicines, is convenient to use, has an obvious treatment effect on muscae volitantes, can obviously improve after being continuously used for about 10 days generally, and can not relapse within a long time after being continuously used for about 30-40 days.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1
A Chinese medicinal compound vision patch for treating ophthalmic diseases comprises: traditional Chinese medicine components, additives and a sticking film. The traditional Chinese medicine comprises the following components: semen plantaginis, herba Senecionis Scandentis, rhizoma anemarrhenae, semen Armeniacae amarum, and herba Taraxaci, wherein the total mass of semen plantaginis, herba Taraxaci and semen Armeniacae amarum is more than 60% of the total mass of the Chinese medicinal components.
The plantain seed is 20 parts by mass, the groundsel is 8 parts by mass, the rhizoma anemarrhenae is 3 parts by mass, the almond is 22 parts by mass, and the dandelion is 18 parts by mass.
Example 2
A Chinese medicinal compound vision patch for treating ophthalmic diseases comprises: traditional Chinese medicine components, additives and a sticking film. The traditional Chinese medicine comprises the following components: semen plantaginis, herba Senecionis Scandentis, rhizoma anemarrhenae, semen Armeniacae amarum, and herba Taraxaci, wherein the total mass of semen plantaginis, herba Taraxaci and semen Armeniacae amarum is more than 60% of the total mass of the Chinese medicinal components.
The traditional Chinese medicine composition comprises, by mass, 30 parts of plantain seeds, 10 parts of groundsel, 5 parts of rhizoma anemarrhenae, 25 parts of almonds and 20 parts of dandelion.
Example 3
A Chinese medicinal compound vision patch for treating ophthalmic diseases comprises: traditional Chinese medicine components, additives and a sticking film. The traditional Chinese medicine comprises the following components: semen plantaginis, herba Senecionis Scandentis, rhizoma anemarrhenae, semen Armeniacae amarum, and herba Taraxaci, wherein the total mass of semen plantaginis, herba Taraxaci and semen Armeniacae amarum is more than 60% of the total mass of the Chinese medicinal components.
The plantain seed is 15 parts by mass, the groundsel is 5 parts by mass, the rhizoma anemarrhenae is 2 parts by mass, the almond is 20 parts by mass, and the dandelion is 15 parts by mass.
Example 4
The traditional Chinese medicine compound vision patch for treating the ophthalmic diseases based on any one of the embodiments 1 to 3 comprises the following additives: acrylamide and potassium persulfate. The film comprises: a viscose patch A for storing Chinese medicinal components and a smooth patch B for storing viscose patch A.
The compound eyesight patch is prepared by taking semen plantaginis, dandelion and almond as a component A and senecio scandens and rhizoma anemarrhenae as a component B, and the preparation method of the compound eyesight patch comprises the following steps:
s1, mixing the component A with 4 times of water by mass, and then carrying out decoction operation A.
S2, after the decoction operation A is finished, carrying out solid-liquid separation through filter cloth to obtain a solid-phase component A and a liquid-phase component A.
S3, mixing the liquid-phase component A with the component B, and then carrying out decoction operation B. And after the decoction operation B is finished, carrying out solid-liquid separation through filter cloth to obtain a solid-phase component B and a liquid-phase component B.
S4, crushing the solid phase component A to 100 meshes, and crushing the solid phase component B to 160 meshes. Then mixing the crushed products of the two to obtain a mixture. Baking the liquid phase component B at 125 ℃ until the mass of the liquid phase component B is reduced by 73 percent to obtain a liquid phase component C.
S5, adding 9 mass percent of acrylamide in the liquid phase component C into the liquid phase component C, and adding 0.4 mass percent of potassium persulfate into the mixture. Then, the two were mixed and reacted at 88 ℃ for 8 minutes to obtain a paste.
S6, smearing paste at the set position of the patch A, flattening, and then covering the patch B on the patch A to obtain the traditional Chinese medicine compound vision patch for treating the ophthalmic diseases.
The decoction operation A comprises the following steps: putting the mixture of the component A and water into a closed container to submerge the component A in the water. Then heating to 112 ℃ for decoction for 32 minutes.
The decoction operation B comprises the following steps: putting the mixture of the liquid-phase component A and the component B into a closed container to enable the liquid-phase component A to submerge the component B. Then heating to 122 ℃ for decoction for 22 minutes.
Example 5
The traditional Chinese medicine compound vision patch for treating the ophthalmic diseases based on any one of the embodiments 1 to 3 comprises the following additives: acrylamide and potassium persulfate. The film comprises: a viscose patch A for storing Chinese medicinal components and a smooth patch B for storing viscose patch A.
The compound eyesight patch is prepared by taking semen plantaginis, dandelion and almond as a component A and senecio scandens and rhizoma anemarrhenae as a component B, and the preparation method of the compound eyesight patch comprises the following steps:
s1, mixing the component A with water of which the mass is 5 times that of the component A, and then carrying out decoction operation A.
S2, after the decoction operation A is finished, carrying out solid-liquid separation through filter cloth to obtain a solid-phase component A and a liquid-phase component A.
S3, mixing the liquid-phase component A with the component B, and then carrying out decoction operation B. And after the decoction operation B is finished, carrying out solid-liquid separation through filter cloth to obtain a solid-phase component B and a liquid-phase component B.
S4, crushing the solid phase component A to 120 meshes, and crushing the solid phase component B to 180 meshes. Then mixing the crushed products of the two to obtain a mixture. And (3) baking the liquid-phase component B at 130 ℃ until the mass of the liquid-phase component B is reduced by 75 percent to obtain a liquid-phase component C.
S5, adding 10 mass percent of acrylamide in the liquid phase component C into the liquid phase component C, and adding 0.5 mass percent of potassium persulfate into the mixture. Then, the two were mixed and reacted at 90 ℃ for 10 minutes to obtain a paste.
S6, smearing paste at the set position of the patch A, flattening, and then covering the patch B on the patch A to obtain the traditional Chinese medicine compound vision patch for treating the ophthalmic diseases.
The decoction operation A comprises the following steps: putting the mixture of the component A and water into a closed container to submerge the component A in the water. Then heating to 115 ℃ for decoction for 35 minutes.
The decoction operation B comprises the following steps: putting the mixture of the liquid-phase component A and the component B into a closed container to enable the liquid-phase component A to submerge the component B. Then heating to 125 ℃ for decoction for 25 minutes.
Example 6
The traditional Chinese medicine compound vision patch for treating the ophthalmic diseases based on any one of the embodiments 1 to 3 comprises the following additives: acrylamide and potassium persulfate. The film comprises: a viscose patch A for storing Chinese medicinal components and a smooth patch B for storing viscose patch A.
The compound eyesight patch is prepared by taking semen plantaginis, dandelion and almond as a component A and senecio scandens and rhizoma anemarrhenae as a component B, and the preparation method of the compound eyesight patch comprises the following steps:
s1, mixing the component A with 3 times of water by mass, and then carrying out decoction operation A.
S2, after the decoction operation A is finished, carrying out solid-liquid separation through filter cloth to obtain a solid-phase component A and a liquid-phase component A.
S3, mixing the liquid-phase component A with the component B, and then carrying out decoction operation B. And after the decoction operation B is finished, carrying out solid-liquid separation through filter cloth to obtain a solid-phase component B and a liquid-phase component B.
S4, crushing the solid phase component A to 80 meshes, and crushing the solid phase component B to 150 meshes. Then mixing the crushed products of the two to obtain a mixture. Baking the liquid phase component B at 120 ℃ until the mass of the liquid phase component B is reduced by 70 percent to obtain a liquid phase component C.
S5, adding acrylamide accounting for 8% of the mass of the liquid phase component C into the liquid phase component C, and adding potassium persulfate accounting for 0.3% of the mass of the mixture into the mixture. Then, the two were mixed and reacted at 80 ℃ for 5 minutes to obtain a paste.
S6, smearing paste at the set position of the patch A, flattening, and then covering the patch B on the patch A to obtain the traditional Chinese medicine compound vision patch for treating the ophthalmic diseases.
The decoction operation A comprises the following steps: putting the mixture of the component A and water into a closed container to submerge the component A in the water. Then heating to 110 ℃ for decoction for 30 minutes.
The decoction operation B comprises the following steps: putting the mixture of the liquid-phase component A and the component B into a closed container to enable the liquid-phase component A to submerge the component B. Then heating to 120 ℃ for decoction for 20 minutes.
Example 7
The traditional Chinese medicine compound vision patch for treating the ophthalmic diseases based on any one of the embodiments 1 to 3 comprises the following additives: acrylamide and potassium persulfate. The film comprises: a viscose patch A for storing Chinese medicinal components and a smooth patch B for storing viscose patch A.
The compound eyesight patch is prepared by taking semen plantaginis, dandelion and almond as a component A and senecio scandens and rhizoma anemarrhenae as a component B, and the preparation method of the compound eyesight patch comprises the following steps: the component A is crushed to 100 meshes, and the component B is crushed to 160 meshes. Then, the two were mixed, acrylamide of the same mass as in example 4 was added, and a potassium persulfate bucket of the same mass and concentration as in example 4 was also mixed, and reacted at 88 ℃ for 8 minutes to obtain a paste. And smearing the paste at the formulated position of the patch A, flattening, and then covering the patch B on the patch A to obtain the traditional Chinese medicine compound vision patch for treating the ophthalmic diseases.
The effects of examples 4-7 after actual use are shown in the following table, using methods: the plaster is applied once a day in the morning and at night for 20 minutes. The position of the patch is affected eye, and the patient closes the eye and then pastes the patch.
Therefore, the compound vision patch prepared by directly using the ointment prepared from the traditional Chinese medicine components has a better treatment effect. However, the compound vision patch prepared by the preparation method is better in effect, the onset time and the treatment time are obviously shortened, and no recurrent cases are found.
It is to be noted and understood that various modifications and improvements can be made to the invention described in detail above without departing from the spirit and scope of the invention as claimed. Accordingly, the scope of the claimed subject matter is not limited by any of the specific exemplary teachings provided.
Claims (1)
1. A traditional Chinese medicine compound vision patch for treating muscae volitantes is characterized in that: is prepared from Chinese medicinal components, additives and a film; the traditional Chinese medicine components comprise semen plantaginis, groundsel, rhizoma anemarrhenae, almond and dandelion, wherein the sum of the mass of the semen plantaginis, the mass of the dandelion and the almond accounts for more than 60% of the total mass of the traditional Chinese medicine components;
15-30 parts of semen plantaginis, 5-10 parts of groundsel, 2-5 parts of rhizoma anemarrhenae, 20-25 parts of almond and 15-20 parts of dandelion;
the additive is acrylamide and potassium persulfate; the film comprises: a viscose patch A for storing Chinese medicinal components and a smooth patch B for storing viscose patch A.
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| CN202010986996.3A CN111991502B (en) | 2020-09-18 | 2020-09-18 | Traditional Chinese medicine compound vision plaster for treating ophthalmic diseases |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102986937A (en) * | 2011-09-13 | 2013-03-27 | 江月锋 | Coffee Senna healthcare tea for liver heat and conjunctival congestion |
| CN104784446A (en) * | 2015-04-29 | 2015-07-22 | 金先琦 | Traditional Chinese medicine for treating muscae volitantes |
| CN106214811A (en) * | 2016-09-29 | 2016-12-14 | 山东正瑞生物股份有限公司 | A kind of Chinese herb medicine eye paste eliminating muscae volitantes and preparation method |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050058730A1 (en) * | 2003-09-15 | 2005-03-17 | Xushan Wan | Compositions and methods for preventing or treating eyestrain |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102986937A (en) * | 2011-09-13 | 2013-03-27 | 江月锋 | Coffee Senna healthcare tea for liver heat and conjunctival congestion |
| CN104784446A (en) * | 2015-04-29 | 2015-07-22 | 金先琦 | Traditional Chinese medicine for treating muscae volitantes |
| CN106214811A (en) * | 2016-09-29 | 2016-12-14 | 山东正瑞生物股份有限公司 | A kind of Chinese herb medicine eye paste eliminating muscae volitantes and preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 五子衍宗丸治疗飞蚊症疗效观察;史素兰;《山西职工医学院学报》;19971231;第7卷(第01期);39 * |
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