CN111991055A

CN111991055A - Catheter assembly capable of removing blood vessel occlusion plaque

Info

Publication number: CN111991055A
Application number: CN202010987364.9A
Authority: CN
Inventors: 王卫; 孙冰茹
Original assignee: Suzhou Chaochao Consulting Service Co ltd
Current assignee: Suzhou Chaochao Consulting Service Co ltd
Priority date: 2020-09-18
Filing date: 2020-09-18
Publication date: 2020-11-27

Abstract

The invention discloses a catheter assembly capable of removing blood vessel occlusion plaques, which comprises a balloon catheter, wherein the balloon catheter comprises an inner catheter and a balloon which is arranged on the inner catheter and can be expanded, the catheter assembly also comprises a first catheter which can be sleeved outside the balloon catheter in a relatively sliding manner, a second catheter which can be sleeved outside the first catheter in a relatively sliding manner, and a filter screen sleeve with a meshed peripheral wall, wherein the filter screen sleeve can be sleeved outside the first sleeve in a relatively sliding manner, the front end part of the filter screen sleeve is fixedly connected to the front part of the first catheter, and the rear end part of the filter screen sleeve is fixedly connected to the front part of the second catheter. After removing the calcified plaque blocked in the blood vessel, the catheter assembly can be used for removing the broken calcified plaque from the blood vessel, and the risk that the calcified plaque is still left in the blood vessel and flows along with the blood is avoided. The catheter assembly is simple in structure and convenient to operate.

Description

Catheter assembly capable of removing blood vessel occlusion plaque

Technical Field

The present invention relates to a catheter assembly capable of removing blood vessel occlusion plaque.

Background

The calcification of blood vessels means that calcium salt deposits exist in the wall of the artery and vein blood vessels, namely, calcified spots on the inner wall of the artery and vein, and the health of patients is seriously threatened. In recent years, for calcium deposition in blood vessels, it is common to insert a catheter provided with a balloon into a blood vessel by means of a small procedure, inflate the balloon when it reaches the calcium deposition site, and work with electrodes disposed in the balloon to release a high voltage pulse, thereby forming a shock wave that propagates through the fluid and strikes the balloon wall and calcified areas to destroy the calcium deposition with the repeated pulse.

In the prior art, most of the methods for generating shock waves in the human body are used for removing calcified plaques in blood vessels of the human body, which needs to generate higher high-voltage pulses in the human body, and the generated pulses promote the liquid filled in the balloon to generate bubbles, so that the bubbles act on the balloon wall when being ruptured, and then act on the calcified plaques. However, the thickness of the blood vessels at different positions on the same blood vessel of the human body is different, and if the shock wave generated by the pulse is too large, the blood vessels are damaged to a certain extent, so the technology for eliminating the calcified plaque in the human body by adopting the pulse is not applied to the clinic.

To safely and effectively remove calcified plaque in blood vessels, chinese patent publication No. CN 109953799 a discloses an ultrasonic balloon catheter assembly, a catheter system and a method of use, in which calcified plaque in blood vessels of a human body is removed by using a method of forming ultrasonic waves in the human body. However, this solution only solves the problem of removing calcified plaque, but the removed plaque still remains in the blood vessel, and if it cannot be taken out of the blood vessel of the human body, it will flow along with the blood to other parts of the body, such as the heart, which brings a great threat to the health of the postoperative patient.

Disclosure of Invention

It is an object of the present invention to provide a catheter assembly capable of removing occluded plaque from a blood vessel, thereby removing calcified plaque from the blood vessel.

In order to achieve the purpose, the invention adopts the technical scheme that: a catheter assembly capable of removing blood vessel occlusion plaque, the catheter assembly comprising a balloon catheter, the balloon catheter comprises an inner catheter and a balloon which is arranged on the inner catheter and can be expanded, the inner catheter axially penetrates through the inner cavity of the balloon and can introduce fluid into the inner cavity of the balloon, the periphery of the balloon is connected with the inner catheter in a sealing way, the catheter assembly also comprises a first catheter which can be sheathed outside the balloon catheter in a relatively sliding way and a second catheter which can be sheathed outside the first catheter in a relatively sliding way, and a filter screen sleeve with a reticular peripheral wall, wherein the filter screen sleeve can be sleeved outside the first sleeve in a relatively sliding way, the front end of the screen sleeve is fixedly connected to the front portion of the first conduit, and the rear end of the screen sleeve is fixedly connected to the front portion of the second conduit.

Preferably, the front end of the screen sleeve is fixedly connected to the first connecting position of the first conduit, the rear end of the screen sleeve is fixedly connected to the second connecting position of the second conduit, the screen sleeve has a retracted state and an opened state, when the screen sleeve is in the retracted state, the distance between the first connecting position and the second connecting position is the same as the length of the screen sleeve, and the screen sleeve is sleeved outside the first conduit in a cylindrical shape; when the filter screen sleeve pipe is in an open state, the distance between the first connecting position and the second connecting position is smaller than the length of the filter screen sleeve pipe, and the filter screen sleeve pipe is sleeved outside the first conduit pipe in a frustum shape.

Further, when the screen sleeve is in an open state, the screen sleeve is crushed and deformed to form the frustum shape and a recovery screen capable of collecting vascular plaque.

Further, the recovery strainer has a frustum shape with a large front end area and a small rear end area.

Still further, the recovery screen includes a first tapered portion and a second tapered portion joined at a leading end, the first tapered portion extending forwardly and obliquely outwardly from the second connection location, the second tapered portion extending forwardly and obliquely outwardly from the first connection location, and the second tapered portion being located in the first tapered portion.

Still further, the recovery screen is formed when a distance between the first connection position and the second connection position is less than a half length of the screen sleeve.

Preferably, the screen sleeve is a cylinder woven from a flexible strip of wire or high strength PP material.

Preferably, the catheter assembly further comprises a protective sleeve which can be sleeved outside the second catheter and the filter screen sleeve in a relatively sliding manner.

Preferably, a first handle is fixedly arranged at the rear part of the first conduit, a second handle is fixedly arranged at the rear part of the second conduit, and a lock catch capable of fixing the first handle and the second handle relatively is arranged between the first handle and the second handle.

Preferably, the catheter assembly further comprises a generating element capable of emitting ultrasound or shock waves, the generating element being disposed in the lumen of the balloon.

Due to the application of the technical scheme, compared with the prior art, the invention has the following advantages: the catheter assembly of the present invention is characterized in that a screen sleeve capable of deforming is provided so as to form a recovery screen capable of recovering calcified plaque after being axially compressed. Thus, after removing the calcified plaque blocked in the blood vessel, the catheter assembly can be used for removing the broken calcified plaque from the blood vessel, and the risk that the calcified plaque is still left in the blood vessel to flow along with the blood is avoided. The catheter assembly is simple in structure and convenient to operate.

Drawings

Fig. 1 is an overall structural schematic view of an ultrasonic balloon catheter system according to embodiment 1 of the present invention;

fig. 2 is a side view of the ultrasonic balloon catheter system of example 1;

FIG. 3 is a schematic sectional view taken along the direction P-P in FIG. 2;

fig. 4 is a schematic longitudinal sectional view of an initial state of the ultrasonic balloon catheter system of example 1;

FIG. 5 is an enlarged view of portion A of FIG. 4;

fig. 6 is a longitudinal sectional view of the ultrasound balloon catheter system according to embodiment 1, in which the first catheter and the second catheter are extended to an initial preset position;

FIG. 7 is an enlarged view of portion B of FIG. 6;

fig. 8 is a longitudinal sectional view of the ultrasonic balloon catheter system according to embodiment 1, after the screen sleeve is switched to the open state;

FIG. 9 is an enlarged view of the portion C of FIG. 8;

FIG. 10 is a schematic longitudinal sectional view of the balloon shown in FIG. 8, as it is extended forwardly to a second predetermined position;

FIG. 11 is an enlarged view of portion D of FIG. 10;

FIG. 12 is a longitudinal sectional view of the balloon inflated with liquid injected therein, based on FIG. 10;

FIG. 13 is an enlarged view of section E of FIG. 12;

FIG. 14 is a schematic longitudinal sectional view of the balloon moving gradually backward and draining on the basis of FIG. 12;

FIG. 15 is an enlarged view of portion F of FIG. 14;

wherein: 1. a balloon catheter; 11. an inner conduit; 12. a balloon; 13. a liquid injection head; 2. a filter screen sleeve; 21. a first tapered portion; 22. a second tapered portion; 3. a first conduit; 4. a second conduit; 5. protecting the sleeve; 6. an ultrasonic wave generating element; 7. an operating handle; 70. a handle base; 71. a first handle; 72. a second handle; 73. a limiting groove; 8. an ultrasonic control generator; 9. a connecting wire; 10. a blood vessel; 20. calcifying the plaque.

Detailed Description

The technical solution of the present invention is further explained with reference to the drawings and the specific embodiments.

Example 1

The following description of the anteroposterior direction is defined with reference to the direction of penetration of the catheter assembly into the vessel 10 during use of the catheter assembly, wherein the end that enters the vessel 10 first is anterior and vice versa.

Referring to fig. 1 to 3, an ultrasonic balloon catheter system includes a catheter assembly and an ultrasonic wave generating element 6 capable of emitting an ultrasonic wave, and an ultrasonic wave control generator 8 for controlling the operation of the ultrasonic wave generating element 6.

The catheter assembly comprises a balloon catheter 1, the balloon catheter 1 comprises an inner catheter 11 and a balloon 12 which is arranged at the front part of the inner catheter 11 and can be expanded, the inner catheter 11 axially penetrates through the inner cavity of the balloon 12 and can feed fluid into the inner cavity of the balloon 12, the periphery of the balloon 12 is hermetically connected with the inner catheter 11, the inner catheter 11 in the inner cavity of the balloon 12 is provided with a plurality of liquid flow holes which are communicated with the inner cavity of the balloon 12 and the inner cavity of the inner catheter 11, the rear end part of the inner catheter 11 is provided with a liquid injection head 13, liquid enters the inner cavity of the balloon 12 through the liquid flow holes of the inner catheter 11 to expand the balloon 12 by injecting liquid into the liquid injection head 13, or the liquid flows out of the inner catheter 11 from the liquid flow holes in the balloon 12 to shrink the balloon 12. The ultrasonic wave generating element 6 is arranged on the inner catheter 11 and is positioned in the inner cavity of the saccule 12, one end of the connecting wire 9 is connected with the ultrasonic wave generating element 6, and the other end of the connecting wire penetrates out of the saccule 12 and is connected with the ultrasonic wave control generator 8.

The catheter assembly further comprises:

a first catheter 3, wherein the first catheter 3 can be sleeved outside the balloon catheter 1 in a relatively sliding manner;

a second conduit 4, wherein the second conduit 4 can be sheathed outside the first conduit 3 in a relatively sliding way;

the screen sleeve 2, which is cylindrical when not extruded and has a mesh-like peripheral wall, may be formed by weaving a flexible tape made of a high-strength PP material or by weaving a metal wire, preferably a titanium alloy wire. The filter screen sleeve 2 is sleeved outside the first guide pipe 3 in a relatively sliding manner, the front end part of the filter screen sleeve 2 is fixedly connected to the front part of the first guide pipe 3, and the connection position of the filter screen sleeve is a first connection position; the rear end part of the filter screen sleeve 2 is fixedly connected to the front part of the second conduit 4, and the connecting position is a second connecting position;

and the protective sleeve 5 is sleeved outside the second guide pipe 4 and the filter screen sleeve 2 in a relatively sliding manner.

The filter screen sleeve 2 has a retracted state and an opened state according to the condition that the filter screen sleeve is axially extruded, when the filter screen sleeve 2 is in the retracted state, the distance between the first connecting position and the second connecting position is the same as the length of the filter screen sleeve 2, and the filter screen sleeve 2 is sleeved outside the first conduit 3 in a cylindrical shape; when the filter screen sleeve 2 is in the open state, the distance between the first connecting position and the second connecting position is smaller than the length of the filter screen sleeve 2, and the filter screen sleeve 2 is extruded and deformed along the axial direction to be sleeved outside the first guide pipe 2 in a frustum shape.

When the filter screen sleeve 2 is in an open state, the filter screen sleeve 2 is squeezed and deformed to form a frustum shape and a recovery filter screen capable of collecting the vascular plaque 20 is formed, the recovery filter screen is in a frustum shape with a large front end area and a small rear end area, and the calcified plaque located in front of the filter screen sleeve 2 can enter the recovery filter screen and be collected when moving backwards.

Referring specifically to fig. 8 to 15, the recovery screen formed by the screen sleeve 2 in the open state comprises a first tapering portion 21 and a second tapering portion 22 which meet at their front ends, the first tapering portion 21 extending obliquely forwardly and outwardly from the second connection position, the second tapering portion 22 extending obliquely forwardly and outwardly from the first connection position, and the second tapering portion 22 being located in the first tapering portion 21, the recovery screen being formed when the distance between the first connection position and the second connection position is less than half the length of the screen sleeve 2. The screen sleeve 2 in the open state also has a collecting operation state outside the protection sleeve 5 and a recovery operation mode housed in the protection sleeve 5.

Referring to the drawings, the catheter system further comprises an operating handle 7, the operating handle 7 comprises a first handle 71 fixed at the rear part of the first catheter 3, a second handle 72 fixed at the rear part of the second catheter 4, and a lock catch (not shown) capable of relatively separating or fixing the first handle 71 and the second handle 72 is arranged between the two handles. When the first handle 71 and the second handle 72 are fixed with each other through the lock catch, the first conduit 3, the second conduit 4 and the filter screen sleeve 2 can be driven and ensured to synchronously move forwards and backwards; when the first handle 71 and the second handle 72 are separated from each other by releasing the lock, the user can separately drive the first duct 3 backward, so that the screen sleeve 2 is crushed and deformed to be converted from the retracted state to the open state.

The operating handle 7 further comprises a handle seat 70 fixedly arranged at the rear part of the protective sleeve 5, the handle seat 70 is provided with a limiting groove 73 extending along the front-rear direction, the first handle 71 and the second handle 72 are arranged in the limiting groove 73 in a relatively sliding manner, so that the sliding positions of the first guide pipe 3 and the second guide pipe 4 can be limited in actual operation, and meanwhile, when the first handle 71 and/or the second handle 72 are fixed relative to the handle seat 70, the protective sleeve 5 and the first guide pipe 3 and/or the second guide pipe 4 can be ensured to slide synchronously.

The method for using the ultrasonic balloon catheter system of the embodiment is described below with reference to the accompanying drawings:

referring to fig. 3 to 5, the balloon 12 is first kept in an unfilled state and positioned in the first catheter 3, the screen sleeve 2 is in a retracted state, the screen sleeve 2 is axially and extendedly sleeved outside the first catheter 3, the second catheter 4 and the screen sleeve 2 are both positioned in the protection sleeve 5, and the front end of the catheter assembly in this state is advanced into the blood vessel 10 to an initial preset position, which is positioned behind the blood vessel occlusion plaque 20 in the blood vessel 10.

Referring to fig. 6 and 7, the protection sleeve 5 is kept still, and the first conduit 3, the second conduit 4 and the filter screen sleeve 2 are synchronously slid forward and out of the protection sleeve 5 to a first preset position, which is in front of the initial preset position and behind the blood vessel occlusion plaque 20 in the blood vessel 10.

Referring to fig. 8 and 9, holding the second conduit 4 still, the first conduit 3 is pulled backward and slid backward relative to the second conduit 4, so that the screen sleeve 2 is pressed in the axial direction to expand and form a frustum-shaped recovery screen, the front end periphery of which should be in contact with the inner wall of the blood vessel 10 or have only a small gap.

Referring to fig. 10, 11, the balloon 12 is advanced out of the first catheter 3 via the inner catheter 11 to a second preset position, where the balloon 12 is outside the lumen of the first catheter 3 and corresponds to a location in the blood vessel where an occluded calcified plaque 20 is formed.

Referring to fig. 12 and 13, the liquid is injected from the injection head 13, so that the liquid enters the inner cavity of the balloon 12 through the inner catheter 11 to expand the balloon 12, the periphery of the balloon 12 contacts the calcified plaque 20 when the balloon is expanded, and then the ultrasonic wave generating element 6 is started to generate ultrasonic waves for a preset time, and the ultrasonic waves act on the calcified plaque 20 to break the calcified plaque 20 to separate the calcified plaque from the blood vessel wall.

Referring to fig. 14 and 15, the fluid inlet of the inner catheter 11 is opened, i.e. the mouth of the injection head 13 at the rear end is kept open, then the inner catheter 11 is pulled backwards, so that the balloon 12 moves backwards, the balloon 12 is squeezed in the process of moving backwards, so that the liquid in the inner cavity of the balloon is discharged from the inner catheter 11, the rear part of the balloon 12 is gradually contracted, and the front part of the balloon 12 is still kept in a tensioned and inflated state, so that the calcified plaque 20 crushed in the blood vessel is gradually pushed backwards by the balloon 12 to be driven into the recovery screen (i.e. the screen sleeve 2 in the opened state), so that the calcified plaque 20 is completely inserted into the recovery screen until the balloon 12 is accommodated in the first catheter 3 or is directly pulled backwards from the first catheter 3.

Finally, not shown, the first and

second conduits

3, 4 are pulled back simultaneously, so that the recovery screen, in which the calcified slabs 20 are collected, is squeezed and housed into the protective sleeve 5. At this point, the first catheter tube 3, the second catheter tube 4 and the protective sleeve 5 are driven synchronously backward to be removed from the blood vessel 10.

In this way, it is accomplished that the calcified plaque 20 clogged on the peripheral wall of the blood vessel 10 is removed and the removed calcified plaque 20 is removed from the blood vessel 10, avoiding the risk of the calcified plaque 20 remaining in the blood vessel 10 along with the blood flow.

Example 2

Not shown, the main difference between the catheter assembly of the present embodiment and the catheter assembly of embodiment 1 is the difference in the generating elements.

In this embodiment, the ultrasonic wave generating element 6 in the catheter assembly is replaced with a generating element capable of generating a shock wave, so that the shock wave is generated during operation to break and peel off the calcified plaque 20 occluded in the blood vessel from the blood vessel wall.

The above-mentioned embodiments are merely illustrative of the technical idea and features of the present invention, and the purpose thereof is to enable those skilled in the art to understand the contents of the present invention and implement the present invention, and not to limit the scope of the present invention, and all equivalent changes or modifications made according to the spirit of the present invention should be covered in the scope of the present invention.

Claims

1. A catheter assembly capable of removing vascular occlusion plaque, the catheter assembly comprising a balloon catheter including an inner catheter and an inflatable balloon disposed on the inner catheter, the inner catheter passing axially through a lumen of the balloon and capable of passing a fluid into the lumen of the balloon, a peripheral portion of the balloon being in sealed connection with the inner catheter, the catheter assembly characterized in that:

the duct subassembly is still established including establishing with relatively sliding first pipe outside the sacculus pipe, establishing with relatively sliding second pipe outside the first pipe to and the perisporium is netted filter screen sleeve pipe, filter screen sleeve pipe is established with relatively sliding first outside the pipe, filter screen sheathed tube preceding tip fixed connection be in on the front portion of first pipe, filter screen sheathed tube back tip is connected fixedly on the front portion of second pipe.

2. A catheter assembly capable of removing occluded plaque from blood vessels as defined in claim 1, wherein: the front end part of the filter screen sleeve is fixedly connected to a first connecting position of the first conduit, the rear end part of the filter screen sleeve is fixedly connected to a second connecting position of the second conduit, the filter screen sleeve has a folding state and an opening state, when the filter screen sleeve is in the folding state, the distance between the first connecting position and the second connecting position is the same as the length of the filter screen sleeve, and the filter screen sleeve is sleeved outside the first conduit in a cylindrical shape; when the filter screen sleeve pipe is in an open state, the distance between the first connecting position and the second connecting position is smaller than the length of the filter screen sleeve pipe, and the filter screen sleeve pipe is sleeved outside the first conduit pipe in a frustum shape.

3. A catheter assembly capable of removing occluded plaque from blood vessels as defined in claim 2, wherein: when the screen sleeve is in an open state, the screen sleeve is extruded and deformed to form the frustum shape and the recovery screen capable of collecting the vascular plaque.

4. A catheter assembly capable of removing occluded plaque from blood vessels as defined in claim 3, wherein: the recovery filter screen is in a frustum shape with a large front end area and a small rear end area.

5. A catheter assembly capable of removing occluded plaque from blood vessels as defined in claim 3, wherein: the recovery filter screen comprises a first conical part and a second conical part, wherein the first conical part and the second conical part are connected at the front end part, the first conical part extends forwards and outwards in an inclined mode from the second connecting position, the second conical part extends forwards and outwards in an inclined mode from the first connecting position, and the second conical part is located in the first conical part.

6. A catheter assembly capable of removing occluded plaque from blood vessels as defined in claim 3, wherein: the recovery screen is formed when the distance between the first connection position and the second connection position is less than half the length of the screen sleeve.

7. A catheter assembly capable of removing occluded plaque from blood vessels as defined in claim 1, wherein: the filter screen sleeve is formed by weaving a flexible belt made of metal wires or high-strength PP materials.

8. A catheter assembly capable of removing occluded plaque from blood vessels as defined in claim 1, wherein: the catheter assembly further comprises a protective sleeve which can be sleeved outside the second catheter and the filter screen sleeve in a relatively sliding mode.

9. A catheter assembly capable of removing occluded plaque from blood vessels as defined in claim 1, wherein: the rear part of the first conduit is fixedly provided with a first handle, the rear part of the second conduit is fixedly provided with a second handle, and a lock catch capable of fixing the first handle and the second handle relatively is arranged between the first handle and the second handle.

10. A catheter assembly capable of removing occluded plaque from blood vessels according to any of claims 1 to 9, wherein: the catheter assembly also includes a generating element capable of emitting ultrasonic or shock waves, the generating element disposed within the lumen of the balloon.