CN111990705A - Coronavirus intelligent monitoring clothes - Google Patents

Coronavirus intelligent monitoring clothes Download PDF

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CN111990705A
CN111990705A CN202010841949.XA CN202010841949A CN111990705A CN 111990705 A CN111990705 A CN 111990705A CN 202010841949 A CN202010841949 A CN 202010841949A CN 111990705 A CN111990705 A CN 111990705A
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module
detection
coating
data
sweat
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罗洁
刘语隆
廖煜容
毛爱华
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Guangzhou University
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Guangzhou University
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    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D1/00Garments
    • A41D1/002Garments adapted to accommodate electronic equipment
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D27/00Details of garments or of their making
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00Materials specially adapted for outerwear
    • A41D31/02Layered materials
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00Materials specially adapted for outerwear
    • A41D31/04Materials specially adapted for outerwear characterised by special function or use
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04WWIRELESS COMMUNICATION NETWORKS
    • H04W4/00Services specially adapted for wireless communication networks; Facilities therefor
    • H04W4/02Services making use of location information
    • H04W4/029Location-based management or tracking services
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7756Sensor type
    • G01N2021/7759Dipstick; Test strip

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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Textile Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
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  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
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  • Cell Biology (AREA)
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  • Computer Networks & Wireless Communication (AREA)
  • Tropical Medicine & Parasitology (AREA)
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Abstract

The invention discloses an intelligent coronavirus monitoring garment which comprises a garment body, a plurality of coating detection modules, a plurality of sensor modules, a control unit and an intelligent mobile phone terminal, wherein the garment body comprises a garment body shell and a plurality of coating detection modules; the coating detection module, the sensor module and the control unit are arranged on the garment body; sweat is collected and is detected to coating detection module, and sensor module collects the result information that detects and conducts the control unit, and the control unit analysis, screening data gather stroke orbit positioning data and give smart mobile phone terminal with data transmission through bluetooth or network, and the user can monitor health status, accomplish health status aassessment and early warning through smart mobile phone terminal. According to the invention, the corresponding coronavirus immune protein in sweat is detected, and the primary home detection of a user is automatically completed by adopting a mode of combining colloidal gold detection and a sensor, so that the online monitoring of the user and the real-time monitoring and evaluation, early warning and screening of people are completed.

Description

Coronavirus intelligent monitoring clothes
Technical Field
The invention belongs to the field of sensor technology and biological coating materials, and relates to an intelligent coronavirus monitoring garment.
Background
Coronaviruses are one of the common main pathogenic microorganisms infecting human beings and causing health hazards, along with the development of epidemic situations, a plurality of nucleic acid detection methods applied to new coronaviruses are rapidly developed at home and abroad, most of the coronaviruses are based on a real-time fluorescent quantitative PCR (qPCR) technology, and in addition, a great number of rapid gene detection technologies are also proposed, such as a field rapid inspection (POCT) technology, a cassette fluorescent PCR technology and the like, and the technologies are required to be carried out in laboratories with conditions and qualification, so that the requirements on equipment, personnel and operation are high, and the duration is long. Zhang robe, etc. indicates that nucleic acid detection mainly uses nasopharyngeal swab, and improper material selection and different virus loads at different parts easily result in poor sample quality, thereby causing false negative result.
The invention provides an epidemic situation monitoring method and system based on a wearable body temperature sensor, which are provided by Liguanhua et al.
Huang Zhen Hai et al ' an information safety monitoring system based on big data ' discloses an information safety monitoring system based on big data, and this has big data technology front end not to detect the technique, and only regional drawing is reported, and big data monitoring technology exists the user and reports, does not know self health state and can't track user action track defect such as not reporting, simultaneously, in the path of confirming the patient, does not have automatic alarm to inform other people that probably have action track coincidence, at present in seeking the track of the suspected crowd that contacts, need to rely on special staff or police to screen the suspected case action track.
Disclosure of Invention
The invention mainly aims to overcome the defects of the prior art, provides a coronavirus intelligent detection suit based on a sweat measurement method and a colloidal gold detection method of an IgM/IgG detection principle, realizes home self-detection and real-time monitoring and evaluation, early warning and screening of isolated people, improves the accuracy of home virus detection, and improves the situation that the existing home detection only takes temperature as a standard.
In order to achieve the purpose, the invention adopts the following technical scheme:
the invention provides an intelligent coronavirus monitoring garment which comprises a garment body, a plurality of coating detection modules, a plurality of sensor modules, a control unit and an intelligent mobile phone terminal, wherein the garment body comprises a garment body shell and a plurality of coating detection modules; the coating detection module, the sensor module and the control unit are arranged on the garment body, and the control unit is in communication with the smart phone terminal in a wireless mode;
the coating detection module is used for collecting sweat and detecting the sweat, and comprises a coating protection module and a sweat detection module; the sweat detection module comprises a plurality of time-interval detection subintervals, and a detection coating is arranged on each time-interval detection subinterval and used for sweat detection;
the sensor module is used for collecting and reading a sweat detection result of the coating detection module;
the control unit is used for caching, analyzing, screening data, positioning, communicating with the smart phone terminal and sending the data to the smart phone terminal;
the intelligent mobile phone terminal is used for providing data visualization, health report and health early warning functions according to monitoring information;
sweat is collected and is detected to coating detection module, and sensor module collects the result information that detects and conducts the control unit, and the control unit analysis, screening data gather stroke orbit positioning data and give smart mobile phone terminal with data transmission through bluetooth or network, and the user can monitor health status, accomplish health status aassessment and early warning through smart mobile phone terminal.
As a preferred technical scheme, the coating protection module is used for protecting the detection coating and comprises a glue pressing waterproof film coating layer and a coating glue pressing; the glue pressing waterproof film coating layer is made of an EPTFE material and is arranged on the outer side of the coating glue pressing; the coating moulding compound is used for protecting the detection coating; the detection coating is arranged in the clothing body by adopting a biological textile technology, and specifically is a multilayer detection test paper which comprises a protective layer, a chromatography layer, a binding layer, a detection layer and a quality control layer.
As a preferred technical scheme, the protective layer is made of a unidirectional polymer material and is used for preventing the test paper from being affected with damp; the chromatographic protective layer is used for protecting the chromatographic layer; the chromatography layer adopts a net structure and is used for filtering impurities irrelevant to detection in sweat; the binding layer and the detection layer are provided with colloidal gold for binding reaction with sweat; the quality control layer is provided with a flowing medium, and the products of the binding reaction in the binding layer and the detection layer generate a color reaction in the quality control layer.
As a preferred technical solution, the chromatography protection layer is also used for blocking reverse osmosis of the flowing medium of the quality control layer.
As a preferred technical scheme, the sensor module comprises a color sensor and a data acquisition module, wherein the color sensor is used for sensing a coating detection result; each detection coating all is furnished with the color sensor, and every color sensor sets up the bottom surface at the detection coating that corresponds and is connected with the sensor.
The sweat detection method is based on an IgM/IgG detection principle, and a colloidal gold detection method are used for detecting sweat, the principle is a double-antibody sandwich colloidal gold test method, detection indexes are conjugates of a gold-labeled antigen, an immune protein product IgM, an antigen-specific antibody and an immune protein product IgM antibody, the three conjugate indexes generate a chromogenic reaction when a quality control layer in a detection coating of the monitoring garment performs a positive reaction, the color sensor monitors whether the chromogenic reaction occurs, and if the color sensor induces color block variation in the detection coating, a data acquisition module of the color sensor uploads acquired data to a control unit; the colloidal gold component in the detection coating contains a gold label, and the gold label is combined with the antigen in the sweat of the detector to generate a gold label antigen.
As a preferred technical scheme, the control unit comprises a data cache module, a data analysis and screening module, a GPRS positioning module, a communication module and a power supply module;
the data cache module is used for converting the signals transmitted by the sensor module into digital signals, ensuring the accuracy of the data through signal filtering and storing the acquired data in a cache space for recording or waiting to be sent; the data analysis and screening module is used for analyzing and screening useful information of the data in the cache space; the GPRS positioning module is used for recording a travel track of a user; the communication module is used for communicating with the smart phone terminal and supporting Bluetooth, GSM and WIFI networks; the power supply module is used for supplying power to all components of the control unit.
As a preferred technical scheme, the smart phone terminal comprises a data receiving module, a data storage module, a data visualization module, a health report module, a health early warning module and a big data report module;
the data receiving module is used for receiving the information transmitted by the control unit; the data storage module is used for storing information; the data visualization module is used for generating pictures and texts according to the data, so that reading is facilitated; the health report module is used for generating a health report according to the health information of the user; the health early warning module is used for early warning the user and sending information to a mobile phone and a mailbox of the user after a health monitoring result of the user reaches a set judgment threshold; the big data reporting module is a module for matching the path and time of the information of the user diagnosed in the period based on the big data of the user, and can combine the real-time position and radiation range of the user with risk reminding, so that the surrounding conditions can be known among the users through views.
As a preferable technical scheme, the time-interval detection subinterval is divided into a main sweat area interval and a secondary sweat area interval according to the distribution of human body physiological sweat.
As a preferred technical solution, the generating of the health report and the health warning includes the following states:
in the first reporting and early warning prompting mode, the detection coatings in the sub-intervals of more than or equal to 6 time intervals are subjected to color reaction, a patient is judged, the health reporting module and the health early warning module send hospitalization information and detection department help information to the patient, and the big data reporting module reports the journey history and monitoring data of the patient and sends an alarm, an anonymous journey circuit diagram of the patient and a radiated range to other users;
in the second report and early warning prompting mode, 3 to 5 time-interval detection subintervals are subjected to color reaction, and the number of the sub-sweat area intervals is less than 3, so that the sub-sweat area intervals are judged to be highly suspected cases, the health early warning module pushes suggestions and guidelines to users, and the users who do not worry about the results can perform other detection or seek medical advice according to the suggestions to ensure health;
a third reporting and early warning prompting mode, namely, if the color reaction occurs in more than or equal to 3 secondary sweat areas, judging the patient to be the same as the first mode;
the report and early warning prompt mode is four, wherein 1 to 3 time-interval detection subintervals have color reaction and are main sweat area intervals, the mild suspected cases are judged, the smart phone terminal generates a percentile graph by using the data visualization module, the health report module and the health early warning module to subdivide the specific percentage from mild to high and push suggestions and guidelines, and users who do not worry about results can perform other detection or medical treatment according to the guidelines to ensure health;
a fifth reporting and early warning prompting mode, wherein a color reaction occurs in less than or equal to 1 main sweat area, and the index is low according to judgment of the sensor module, and the index is still judged to be healthy;
and in a report and early warning prompting mode six, zero time-interval detection subintervals are subjected to color reaction, and the health is judged.
Compared with the prior art, the invention has the following advantages and beneficial effects:
1. the detection mode of the invention has higher pathological detection scientific basis, and the sweat measurement method and the colloidal gold detection method based on the IgM/IgG detection principle of the invention avoid unscientific taking body temperature as an index; in addition, the invention diagnoses whether the testee suffers from the coronavirus through a method of multiple steps and simultaneous testing of multiple points of the human body, thereby greatly improving the detection accuracy.
2. The method is based on a big data cloud technology, real-time GPRS positioning is carried out on the users, travel tracking and recording are carried out, the travel track of each user is overlapped, the detection result is the user travel record of the patient and is accurately reported, and alarm reminding is carried out on other users, so that a set of complete anonymous data statistics, travel tracks and hospitalizing alarm system for the patients suffering from the coronavirus is formed. The invention uploads the journey information of the patient anonymously, thereby protecting the privacy of each user.
3. The detection method involved in the invention can detect asymptomatic confirmed population infected by coronavirus.
4. The advanced detection mode of the invention can solve the defects of low accuracy of the existing in vitro detection: according to research on coronavirus, the coronavirus has the characteristic of high variability and rapidness, the judgment is fuzzy when the result relates to body temperature amplification intersection by taking the body temperature as a judgment standard, even whether the coronavirus is infected or the conventional fever cannot be identified, and the accuracy is greatly fuzzy. The invention adopts a coating detection technology based on a colloidal gold detection method, and immune protein (IgM/IgG) generated after human infection with coronavirus is used for detection. Put into coating detection module on intelligent clothes to use the moulding process to protect the coating after the degerming technique, the filtration of coating can adsorb the immune protein to coronavirus that generates in catching human sweat, combines rather than at the reaction layer and generates the color reaction. Can be identified by visually identifying whether the coating generates color spots or blocks. The control unit judges the color reaction of the coating and diagnoses the user, and utilizes a plurality of data acquisition, thereby greatly solving the inaccuracy existing in the colloidal gold test method.
5. The invention overcomes the defect that the prior big data software has no front end, and the built-in color sensor module and the intelligent mobile phone terminal developed by matching with the color sensor module can well interact with the user.
6. The existing data processing platform such as ciokang and urban health codes under the Paibao flag all adopt a data self-reporting mode, so that the situations of false reporting and false reporting exist, a built-in control unit in the invention carries a GPRS positioning module, so that the specific situation travel of a user can be accurately recorded, and the detection logic of multipoint advanced judgment used by the invention is matched, so that useless information can be filtered out, and the crowd data judged as a patient can be accurately reported.
7. The coatings of the present invention can also be used for monitoring of various coronaviruses after changing the coating formulation.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2a is a schematic view of a coating detection module according to the present invention;
FIG. 2b is a schematic view of a coating detection module according to the present invention
FIG. 3 is a schematic view of the composition of the detection coating in the time-phased detection zone of the present invention;
FIG. 4 is a schematic of the binding reaction for sweat detection according to the present invention;
fig. 5 is a schematic diagram of a male pattern of an intelligent monitoring garment according to a first embodiment of the invention;
FIG. 6 is a distribution of male sweating regions;
fig. 7 is a schematic diagram of a female pattern of the intelligent monitoring suit according to the second embodiment of the invention;
FIG. 8 is a distribution of female sweating regions;
FIG. 9a is a schematic illustration of a candidate region of the coating detection module of the present invention;
FIG. 9b is a schematic illustration of a candidate region of the coating detection module of the present invention;
the reference numbers illustrate: 1. a garment body; 2. a coating detection module; 3. a sensor module; 4. a control unit; 5. a smartphone terminal; 21. a coating protection module; 22. a sweat detection module; 32. a data acquisition module; 41. a data caching module; 42. a data analysis and screening module; 43. a GPRS positioning module; 44. a Bluetooth/GSM/WIFI communication module; 45. a power supply module; 51. a data receiving module; 52. a data storage module; 53. a data visualization module; 54. a health report module; 55. a health early warning module; 56. A big data reporting module; 21-1, pressing a glue waterproof film coating layer; 21-2, coating and glue pressing; 22-1 to 22-14, detecting subintervals at different time intervals; 22-a1, protective layer; 22-A2, a chromatographic protective layer; 22-A3, chromatography layer; 22-a4, binding layer 22-a5, detection layer; 22-A6, quality control layer; 31-1 to 31-14, a color sensor.
Detailed Description
The present invention will be described in further detail with reference to examples and drawings, but the present invention is not limited thereto.
The sweat measuring method and the colloidal gold measuring method based on the IgM/IgG detection principle adopt a step multi-point combined measuring method to diagnose whether a person to be detected suffers from coronavirus, thereby greatly improving the detection accuracy; meanwhile, based on a big data cloud technology, real-time GPRS positioning is carried out on users, travel tracking and recording are carried out, travel tracks of all the users are overlapped, detection results are accurately reported for the user travel records of patients, alarm reminding is carried out on other users, a set of complete anonymous data statistics, travel tracks and hospitalizing alarm system for people suffering from coronavirus is formed, and finally home self-detection, real-time monitoring and evaluation of isolated people, early warning and screening are achieved.
Examples
As shown in fig. 1, the intelligent coronavirus monitoring garment comprises a garment body 1, a coating detection module 2, a sensor module 3, a control unit 4 and a smartphone terminal 5; the coating detection module 2, the sensor module 3 and the control unit 4 are arranged on the garment body 1, and the control unit 4 is in wireless communication with the smart phone terminal 5.
The coating detection module 2 comprises a coating protection module 21 and a sweat detection module 22; the sweat detection module comprises a plurality of time-interval detection subintervals, and a detection coating is arranged on each time-interval detection subinterval and used for sweat detection;
the sensor module 3 comprises a color sensor 31 and a data acquisition module 32;
the control unit comprises a data cache module 41, a data analysis and screening module 42, a GPRS positioning module 43, a Bluetooth/GSM/WIFI communication module 44 and a power supply module 45;
the smartphone terminal comprises a data receiving module 51, a data storage module 52, a data visualization module 53, a health report module 54, a health early warning module 55 and a big data report module 56.
In this embodiment, the reaction result detected by the sweat detecting module 22, if it is positive, generates red color, the reaction result can be recognized by naked eyes, the specific data is collected and read by the sensor module 3, the color sensor module 31 senses the detection result of the detection coating and transmits the result to the data collecting module 32, and then the data is transmitted to the control unit 4 for a series of operations such as data integration processing. The sub-sensors, the color sensor module 31 and the wiring contained in the coating detection module 2 and the sensor module 3 are placed at the positions of the chest, the back waist, the abdomen, the back and the like of the inner layer of the clothing body according to the distribution of human physiological sweat, and the wiring is placed according to the trend of human muscles and does not generate foreign body sensation to the human body.
In this embodiment, as shown in fig. 2a and 2b, the sweat detection module includes 14 time-phased detection sub-intervals, which are a first detection sub-interval 22-1, a second detection sub-interval 22-2, a third detection sub-interval 22-3, a fourth detection sub-interval 22-4, a fifth detection sub-interval 22-5, a sixth detection sub-interval 22-6, a seventh detection sub-interval 22-7, an eighth detection sub-interval 22-8, a ninth detection sub-interval 22-9, a tenth detection sub-interval 22-10, an eleventh detection sub-interval 22-11, a twelfth detection sub-interval 22-12, a thirteenth detection sub-interval 22-13 and a fourteenth detection sub-interval 22-14, each time-phased detection sub-interval includes a detection coating, and each detection coating is provided with a corresponding first color sensor 31-1, A second color sensor 31-2, a third color sensor 31-3, a fourth color sensor 31-4, a fifth color sensor 31-5, a sixth color sensor 31-6, a seventh color sensor 31-7, an eighth color sensor 31-8, a ninth color sensor 31-9, a tenth color sensor 31-10, an eleventh color sensor 31-11, a twelfth color sensor 31-12, a thirteenth color sensor 31-13, and a fourteenth color sensor 31-14.
The color sensors 3 are connected with the control unit 4, and each color sensor is arranged on the bottom surface of the corresponding detection coating; when one detection coating finishes detection, the color sensor monitors whether the detection coating is positive or not, namely, a color change reaction occurs, and if the detection coating is positive, the detection data is transmitted to the control unit 4 through the data acquisition module 32.
In this example, as shown in FIG. 3, the detection coating used in the present invention includes a protective layer 22-A1, a chromatographic protective layer 22-A2, a chromatographic layer 22-A3, a binding layer 22-A4, a detection layer 22-A5, and a quality control layer 22-A6. The detection coating is prepared by placing the original multilayer detection test paper into the antibacterial fiber by using a biological textile technology; the coating protection module comprises a glue pressing waterproof film coating layer 21-1 and a coating glue pressing layer 21-2.
The coating adhesive 21-2 can protect the detection coating. The detection coating is covered with an adhesive pressing waterproof coating layer 21-1, the selected material is EPTFE (polytetrafluoroethylene), the detection coating has waterproof and breathable properties, when a user actually uses the detection coating, the detection coating needs to be torn, sweat of the user permeates into the detection coating from a protective layer 22-A1 after the adhesive pressing waterproof coating layer 21-1 is torn, and the protective layer 22-A1 is a one-way high polymer organic material and has the function of protecting the accuracy of detection and preventing the conditions such as dampness and the like; the chromatographic protective layer 22-A2 is designed for protecting the chromatographic layer 22-A3 and also ensures the accuracy of the detection result. The reticular structure of the chromatographic layer 22-A3 can filter off a part of impurities irrelevant to detection when sweat passes through the chromatographic layer 22-A3, so that substances relevant to detection can continuously permeate into the binding layer 22-A4, a colloidal gold component exists in the binding layer 22-A4, and the colloidal gold component can be combined with an IgM sample and an antigen component existing in the sweat to generate an antigen body with a gold label. The detection layer 22-A5, which functions in the same manner as the binding layer 22-A4. The binding material formed in the quality control layer 22-A6, the binding layer 22-A4 and the detection layer 22-A5 exhibits a color reaction due to the flow medium in the quality control layer 22-A6, and the flow medium permeates backward into the binding layer 22-A4, the detection layer 22-A5 and the chromatography layer 22-A3, but is blocked by the chromatography protective layer 22-A2. In this example, 6mil is used as the adhesive tape width standard, 600 ℃ is the control temperature of the hot-press adhesive machine, the speed is 18FPM/min, and the nozzle air pressure is 17 PSi.
As shown in fig. 4, the detection coating of the present invention binds to the reaction when detecting sweat. The principle of the coating detection in the invention is designed based on a colloidal gold test method and a double-antibody sandwich method colloidal gold test method. The detection indexes comprise gold-labeled antigen D3 with positive reaction, anti-IgM antibody D4, antigen-specific antibody D5, and final conjugate D6, conjugate D7 and conjugate D8. Wherein D1 is IgM which is an immune protein produced by a human body at a specific period after infection with coronavirus. The D3 is a gold-labeled antigen, which is an antigen in sweat attached by colloidal gold and is an essential binding component in a binding reaction, the colloidal gold has a gold label, and the gold label can be combined with the antigen to generate a gold-labeled antigen D3. The D4 is an anti-IgM antibody, which is an antibody present in sweat and capable of binding IgM (D1) to adsorb gold-labeled conjugate D7. The D5 is antigen-specific antibody, is a product in immune reaction, and can generate D8 by the binding reaction with the binding gold-labeled D3. The binder D6, the binder D7 and the binder D8, which are slightly different in composition, all show a color reaction in the quality control layer 22-A6 with positive indicators, and can be captured by the color sensor 31 and upload the collected data to the control unit 4.
In this embodiment, the data buffer module 41 in the control unit converts the conducted signal into a digital signal, and ensures the accuracy of the data through signal filtering, and stores the acquired data in a buffer space for recording or a state to be sent; the data analyzing and screening module 42 analyzes the data collected by the control unit 4 and screens useful information; the GPRS positioning module 43 is used for recording the travel tracks of users when the products are used, overlapping the travel tracks of confirmed users by combining a big data technology to share information, screening infected persons who may contact, and early warning; the Bluetooth/GSM/WIFI communication module 44 is used for connecting the smart phone terminal 5; the power supply module 45 has a charging function and a power storage function, and is used for supplying power to each module in the control unit 4.
In this embodiment, in the smart phone terminal, the data receiving module 51 is configured to be in communication connection with the bluetooth/GSM/WIFI communication module 44 of the control unit 4, and receive data by using a wireless network technology; the data storage module 52 is configured to store the received data, store the received information in a specific file format, so as to facilitate the accuracy of the data, read and export the result, and send the data to the data visualization module 53, or generate result information that facilitates reading and viewing by the user by means of the data displayed by the data visualization module 53; the statement-of-health module 54 will generate reporting data after each use by the user; the health early warning module 55 can perform early warning on the user after a single day or a certain amount of results generated by the user reach a judgment threshold value, and simultaneously send messages to the mobile phone number of the user and the binding mailbox, so that the user can conveniently perform a series of operations such as treatment and the like according to the results shown by the early warning; the big data reporting module 56 is a module for matching the path and time of the information of the user diagnosed in the period based on the big data of the user, and can combine the real-time location and the travel history of the user with the risk reminding by using the GPRS location module 43 and the smartphone terminal 5 to coordinate the real-time location and the travel history of the user, so that the user can know the surrounding situation through the view.
In this embodiment, two coating detection modules 2 and 14 time-phased detection subintervals are set on the garment body 1, and in the smartphone terminal 5, the health report module 54 forms a health report and an early warning mode according to the data of the sweat detection module 22 collected by the color sensor module 31, and presents the following six states, specifically including:
and in the first report and early warning prompt mode, positive reactions are generated in more than or equal to 6 intervals in 14 time-interval detection subintervals, and the patient is judged. The health report module 54 and the health early warning module 55 send the medical advice to the patient, the information big data report module 56 which asks for help from the detection department reports all the journey history and the illness data of the patient, and sends the alarm to other users, and sends the anonymous type circuit diagram of the patient and the radiated range.
And in a second report and early warning prompt mode, the existence of sub-sweat regions in 3 intervals or more in 14 sub-intervals is detected in time intervals, and the sub-sweat regions are positive, so that the patient is judged. The health report module 54 and the health early warning module 55 send information for seeking medical services and help to detection departments, and the big data report module 56 reports all travel history and illness data of the users and sends alarms to other users, and sends anonymous circuit diagrams of patients and radiation ranges.
And a third reporting and early warning prompting mode, wherein if 0 interval in the 14 time-interval detection subintervals is positive, the health is judged.
And in the report and early warning prompting mode, the 14 time-interval detection subintervals are positive in the interval of less than or equal to 1 main sweat area, and the judgment is made according to the sensor, and if the index is low, the judgment is also made to be healthy.
And in the report and early warning prompt mode, 3 to 5 positive intervals exist in 14 sweat detection module subintervals, and the number of the secondary sweat area intervals is less than 3, so that the result is judged to be highly suspected. The user may receive recommendations from the health alert module 55 and the user who is not reassuring the results may perform other tests or medical visits based on guidelines to ensure health.
And in the report and early warning prompt mode, 1 to 3 positive intervals exist in 14 sweat detection module subintervals, and the subintervals do not relate to the secondary sweat area interval, so that the result is judged to be mild suspected. Because there are many situations, the specific situation may be determined by the control unit 4 and generated in the smartphone terminal 5 by using the data visualization module 53, the health report module 54, and the health warning module 55 to subdivide the specific percentage from mild to high. Users who are not reassuring about the results may perform other tests or medical visits according to the guidelines to ensure health.
In the embodiment, as shown in fig. 9a and 9b, the position of the coating detection module 2 used in the present invention may be adjusted according to the actual situation, the user's requirement, or the like, except for the predetermined area, the adjustment may also be performed according to the reasonable situation indicated by the sweat difference map of men and women, and the dotted area in fig. 9a and 9b is the optional area of the coating detection module 2.
In embodiments, the coating recipe of the present invention can also be developed or updated to other recipes by updating the detection method, but the mode of the coating detection and the advanced detection will not change. The detection principle used by the established detection coating module 2 is mode updating and expanding according to a colloidal gold detection method, and colloidal gold chromatography liquid or detection material can be subjected to concentration increase and decrease or material replacement according to actual conditions or technical updating. Other detection methods or detection factors and formulas can be replaced, such as detecting ribonucleic acid molecules in sweat samples, adsorbing new coronavirus RNA possibly existing in sweat by using magnetic nanoparticle materials, and the like. In addition, the detection material is also arranged into the intelligent accessory by the textile technology.
In another embodiment of the application, as shown in fig. 5, the intelligent coronavirus detection clothing male money of the embodiment comprises a clothing body, wherein the clothing body is made by adding an antibacterial deodorant into fibers, the clothing body comprises an inner layer and an outer layer, and the inner layer is provided with a coating detection module 2, a sensor module 3 and a control unit 4.
As shown in fig. 6, the placement area of the detection coating in the first embodiment is set to be the primary and secondary two areas according to the male sweating region. The numerical value is shown as a unit data icon of sweat detection, the minimum unit is defined as being more than or equal to 0, the maximum value is 900+, and the measurement formula is as follows:
the dominant sweating amount (unit: ml/h) is different from the sweating amount (ml) of different shapes/100 cm2X 60/drop formation time (min) x sweat interval visible to the naked eye (cm)2)÷100
The division is carried out by the formula and the common sense of the human body interval, the primary and secondary points of the sweating interval are defined by taking 700 as a unit threshold value, the 700 is summarized as a secondary sweating area, and the 700 is summarized as a primary sweating area (the temporary measuring and judging mode of the invention or the correction of the specific situation is carried out), and the reference document is obtained according to the research progress of the human body sweating rate distribution of the treatise of Zhang Wen Huan and the like. A schematic of the male sweating-front was obtained, with the value 620 being the highest. Schematic on the back of the male sweating-where the value 1050 is highest. Because the selection of the highest 620 region may cause a non-stick condition, which may affect the amount of sweat absorbed by the coating, based on the comparison of the male sweat-front values and ergonomic considerations, it is most preferable to place the coating detection module 2 in the 590 region, and based on the comparison of the male sweat-back values and ergonomic considerations, it is most preferable to place the coating detection module 2 in the highest 1050 region.
In another embodiment of the present application, as shown in fig. 7, the present embodiment is an intelligent coronavirus monitoring suit for women according to distribution of sweat areas of women, which is different from the first embodiment in a set position of a coating detection module 2, and the present embodiment also includes a suit body 1, and the coating detection module 2, a sensor module 3, and a control unit 4 are arranged in an inner layer.
As shown in FIG. 8, a distribution graph of female sweat areas is shown, the numerical values are illustrated as unit data plots for sweat detection, the minimum unit is defined as ≧ 0, the maximum is 900+, and the measurement formula is:
the dominant sweating amount (unit: ml/h) is different from the sweating amount (ml) of different shapes/100 cm2X 60/drop formation time (min) x sweat interval visible to the naked eye (cm)2)÷100;
The division is carried out by the formula and the common sense of the human body interval, the primary and secondary divisions of the sweating interval are defined by taking 700 as a unit threshold value, 700 is generalized to be a secondary sweating area, and on the contrary, 700 is generalized to be a primary sweating area (the provisional measurement and judgment mode of the invention or the correction is carried out due to specific conditions). From the reference of "progress of research on human body sweating rate distribution", it is found that the value 570 is the highest and the value 250 is the lowest in the female sweating-face as shown in fig. 8. Female sweating-the dorsal aspect is the highest value 840 and the lowest value 250. According to the numerical comparison and ergonomic consideration of female sweating-front, the coating detection module 2 is most preferably placed at the abdomen of the woman, and according to the numerical comparison and ergonomic consideration of the sweating zone E4 on the back of the woman, the coating detection module 2 is most preferably placed at the back of the woman, because the chest with the highest numerical range is not attached, which may affect the amount of sweat absorbed by the coating.
The invention can also be implemented on intelligent wearable clothes or clothing equipment such as intelligent coronavirus monitoring clothes, intelligent coronavirus monitoring waistbands, intelligent coronavirus detection stickers and the like. The method can monitor whether the user suffers from the coronavirus or not under the condition of not influencing the sleeping action of the user and the like. The body of the clothes, the clothes or the clothes accessories of the device is not limited to the clothes, fabrics with different materials and colors can be selected according to the requirements of users, the style of the clothes, the appearance of the clothes or the clothes accessories can be changed according to individual requirements, and the detection mode of the invention is not influenced by the style of the clothes, the accessories and the clothes.
It should also be noted that in this specification, terms such as "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (10)

1. The intelligent coronavirus monitoring garment is characterized by comprising a garment body, a plurality of coating detection modules, a plurality of sensor modules, a control unit and a smart phone terminal; the coating detection module, the sensor module and the control unit are arranged on the garment body, and the control unit is in communication with the smart phone terminal in a wireless mode;
the coating detection module is used for collecting sweat and detecting the sweat, and comprises a coating protection module and a sweat detection module; the sweat detection module comprises a plurality of time-interval detection subintervals, and a detection coating is arranged on each time-interval detection subinterval and used for sweat detection;
the sensor module is used for collecting and reading a sweat detection result of the coating detection module;
the control unit is used for caching, analyzing, screening data, positioning, communicating with the smart phone terminal and sending the data to the smart phone terminal;
the intelligent mobile phone terminal is used for providing data visualization, health report and health early warning functions according to monitoring information;
sweat is collected and is detected to coating detection module, and sensor module collects the result information that detects and conducts the control unit, and the control unit analysis, screening data gather stroke orbit positioning data and give smart mobile phone terminal with data transmission through bluetooth or network, and the user can monitor health status, accomplish health status aassessment and early warning through smart mobile phone terminal.
2. The intelligent coronavirus monitoring garment as claimed in claim 1, wherein the coating protection module is used for protecting the detection coating and comprises an adhesive pressing waterproof film coating layer and a coating adhesive pressing layer; the glue pressing waterproof film coating layer is made of an EPTFE material and is arranged on the outer side of the coating glue pressing; the coating moulding compound is used for protecting the detection coating; the detection coating is arranged in the clothing body by adopting a biological textile technology, and specifically is a multilayer detection test paper which comprises a protective layer, a chromatography layer, a binding layer, a detection layer and a quality control layer.
3. The intelligent coronavirus monitoring garment according to claim 2, wherein the protective layer is made of a unidirectional polymer material and is used for preventing the test paper from being affected with damp; the chromatographic protective layer is used for protecting the chromatographic layer; the chromatography layer adopts a net structure and is used for filtering impurities irrelevant to detection in sweat; the binding layer and the detection layer are provided with colloidal gold for binding reaction with sweat; the quality control layer is provided with a flowing medium, and the products of the binding reaction in the binding layer and the detection layer generate a color reaction in the quality control layer.
4. The intelligent coronavirus monitoring garment according to claim 3, wherein the chromatographic protective layer is further used for blocking reverse osmosis of a flowing medium of the quality control layer.
5. The intelligent coronavirus monitoring garment according to claim 1 or 2, wherein the sensor module comprises a color sensor and a data acquisition module, wherein the color sensor is used for sensing a coating detection result; each detection coating all is furnished with the color sensor, and every color sensor sets up the bottom surface at the detection coating that corresponds and is connected with the sensor.
6. The intelligent coronavirus monitoring garment of any one of claims 1-5, wherein the monitoring garment detects sweat by a sweat measurement method based on IgM/IgG detection principle and a colloidal gold detection method, the principle is derived from a double-antibody sandwich colloidal gold test method, the detection indexes are conjugates of a gold-labeled antigen and an immune protein product IgM, an antigen-specific antibody and an immune protein product IgM antibody, the three conjugates indicate that a color development reaction occurs when a quality control layer in a detection coating of the monitoring garment is in a positive reaction, the color sensor monitors whether the color development reaction occurs, and if the color sensor induces a color change in a color block in the detection coating, a data acquisition module of the color sensor uploads the acquired data to the control unit; the colloidal gold component in the detection coating contains a gold label, and the gold label is combined with the antigen in the sweat of the detector to generate a gold label antigen.
7. The intelligent coronavirus monitoring garment as claimed in claim 1, wherein the control unit comprises a data caching module, a data analysis and screening module, a GPRS positioning module, a communication module and a power supply module;
the data cache module is used for converting the signals transmitted by the sensor module into digital signals, ensuring the accuracy of the data through signal filtering and storing the acquired data in a cache space for recording or waiting to be sent; the data analysis and screening module is used for analyzing and screening useful information of the data in the cache space; the GPRS positioning module is used for recording a travel track of a user; the communication module is used for communicating with the smart phone terminal and supporting Bluetooth, GSM and WIFI networks; the power supply module is used for supplying power to all components of the control unit.
8. The coronavirus intelligent monitoring garment as claimed in claim 1, wherein the smartphone terminal comprises a data receiving module, a data storage module, a data visualization module, a health report module, a health early warning module and a big data report module;
the data receiving module is used for receiving the information transmitted by the control unit; the data storage module is used for storing information; the data visualization module is used for generating pictures and texts according to the data, so that reading is facilitated; the health report module is used for generating a health report according to the health information of the user; the health early warning module is used for early warning the user and sending information to a mobile phone and a mailbox of the user after a health monitoring result of the user reaches a set judgment threshold; the big data reporting module is a module for matching the path and time of the information of the user diagnosed in the period based on the big data of the user, and can combine the real-time position and radiation range of the user with risk reminding, so that the surrounding conditions can be known among the users through views.
9. The coronavirus intelligent monitoring garment of claim 1, wherein the time-division detection subinterval is divided into a primary sweat region interval and a secondary sweat region interval according to human body physiological sweat distribution.
10. The intelligent coronavirus monitoring garment of claim 8 or 9, wherein the health report generation and the health alert generation comprise the following states:
in the first reporting and early warning prompting mode, the detection coatings in the sub-intervals of more than or equal to 6 time intervals are subjected to color reaction, a patient is judged, the health reporting module and the health early warning module send hospitalization information and detection department help information to the patient, and the big data reporting module reports the journey history and monitoring data of the patient and sends an alarm, an anonymous journey circuit diagram of the patient and a radiated range to other users;
in the second report and early warning prompting mode, 3 to 5 time-interval detection subintervals are subjected to color reaction, and the number of the sub-sweat area intervals is less than 3, so that the sub-sweat area intervals are judged to be highly suspected cases, the health early warning module pushes suggestions and guidelines to users, and the users who do not worry about the results can perform other detection or seek medical advice according to the suggestions to ensure health;
a third reporting and early warning prompting mode, namely, if the color reaction occurs in more than or equal to 3 secondary sweat areas, judging the patient to be the same as the first mode;
the report and early warning prompt mode is four, wherein 1 to 3 time-interval detection subintervals have color reaction and are main sweat area intervals, the mild suspected cases are judged, the smart phone terminal generates a percentile graph by using the data visualization module, the health report module and the health early warning module to subdivide the specific percentage from mild to high and push suggestions and guidelines, and users who do not worry about results can perform other detection or medical treatment according to the guidelines to ensure health;
a fifth reporting and early warning prompting mode, wherein a color reaction occurs in less than or equal to 1 main sweat area, and the index is low according to judgment of the sensor module, and the index is still judged to be healthy;
and in a report and early warning prompting mode six, zero time-interval detection subintervals are subjected to color reaction, and the health is judged.
CN202010841949.XA 2020-08-20 2020-08-20 Coronavirus intelligent monitoring clothes Pending CN111990705A (en)

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