CN111949058A - Linkage control system and method for indoor temperature and humidity in DNA synthesizer - Google Patents

Linkage control system and method for indoor temperature and humidity in DNA synthesizer Download PDF

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Publication number
CN111949058A
CN111949058A CN202010746954.2A CN202010746954A CN111949058A CN 111949058 A CN111949058 A CN 111949058A CN 202010746954 A CN202010746954 A CN 202010746954A CN 111949058 A CN111949058 A CN 111949058A
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China
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humidity
temperature
synthesizer
control device
synthesizer body
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CN202010746954.2A
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CN111949058B (en
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马石金
朱强
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Tsingke Biotechnology Co Ltd
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Tsingke Biotechnology Co Ltd
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    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05DSYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D27/00Simultaneous control of variables covered by two or more of main groups G05D1/00 - G05D25/00
    • G05D27/02Simultaneous control of variables covered by two or more of main groups G05D1/00 - G05D25/00 characterised by the use of electric means

Abstract

The invention relates to the field of control methods, in particular to a linkage control system and method for indoor temperature and humidity in a DNA synthesizer. The linkage control system for the indoor temperature and the humidity in the DNA synthesizer comprises a detection piece, a detection piece and a control piece, wherein the detection piece is arranged in the synthesizer body and is used for detecting the environmental temperature and the environmental humidity in the synthesizer body; a temperature adjusting device arranged indoors; the humidity adjusting device is arranged in the synthesizer body, and the synthesizer body is arranged in a room; and the control device controls the temperature adjusting device and/or the humidity adjusting device based on a detection signal of the detection piece. This linkage control system of indoor temperature and DNA synthesizer internal humidity can save the manual work to the humidity in the synthesizer body and according to the step of the corresponding ambient temperature who adjusts the position that the synthesizer body is located of experience, has improved the degree of automation and the adaptive capacity of synthesizer body, has further reduced the influence of manual operation to the normal work of synthesizer body.

Description

Linkage control system and method for indoor temperature and humidity in DNA synthesizer
Technical Field
The invention relates to the field of control methods, in particular to a linkage control system and method for indoor temperature and humidity in a DNA synthesizer.
Background
At present, the artificial synthesis of DNA is the only way for the known directional modification of gene sequences, and is widely applied to the fields of protein modification, life science and the like, such as nucleic acid medicine, enzyme engineering, gene detection, gene therapy and the like. The DNA synthesizer resynthesis process needs to carry out the steps of deprotection, activation linking, capping, oxidation and the like. Because the DNA is synthesized based on a phosphorous acid amide chemical synthesis method, the chemical reaction of each step needs to be carried out within a certain temperature and humidity range so as to ensure the synthesis of a DNA sequence with higher quality.
The humidity control chamber of the current DNA synthesizer controls the humidity of a synthesis reaction chamber through a closed cavity, so that the moisture in the air is prevented from entering a reaction environment, however, the synthesis instrument relates to screw fixation, assembly links such as threading and wiring are adopted, the opening of the synthesis cavity is too many, and the sealing cannot be completely realized, so that the quality of the synthesized DNA can be always influenced by the humidity in the air, and the high-quality DNA synthesis cannot be realized. Temperature control only depends on manually setting the temperature of a laboratory so as to indirectly control the temperature of a chamber of a synthesizer, and the method cannot realize accurate temperature control, so that high-quality DNA synthesis is difficult to provide.
Disclosure of Invention
The present invention is directed to solving at least one of the problems of the prior art. Therefore, the invention provides a linkage control system for the indoor temperature and the humidity in the DNA synthesizer, which can accurately adjust the humidity in the synthesizer body and the environmental temperature of the position where the synthesizer body is located, and ensure the normal use of the synthesizer body.
The invention provides a linkage control system for indoor temperature and humidity in a DNA synthesizer, which comprises:
the detection piece is arranged in the synthesizer body and used for detecting the environmental temperature and the environmental humidity in the synthesizer body;
a temperature adjusting device arranged indoors;
the humidity adjusting device is arranged in the synthesizer body, and the synthesizer body is arranged in the chamber;
a control device that controls the temperature adjusting device and/or the humidity adjusting device based on a detection signal of the detection member.
According to the linkage control system for the indoor temperature and the humidity in the DNA synthesizer, provided by the embodiment of the invention, the detection piece is arranged, so that the humidity in the synthesizer body and the environmental temperature of the position where the synthesizer body is located can be accurately detected, the detected humidity and temperature are converted into a humidity signal and a temperature signal, and the humidity signal and the temperature signal are sent to the control device. After controlling means received humidity signal and temperature signal, can compare humidity signal and temperature signal and the humidity threshold value and the temperature threshold value of prestoring in controlling means, and control indoor temperature regulation apparatus according to the comparison result, perhaps control the humidity regulation apparatus in the synthesizer body, thereby realized accurate closed-loop control to the humidity of this internal and the ambient temperature of synthesizer body position, and then can make this internal humidity of synthesizer and the ambient temperature of synthesizer body position all maintain reasonable within range, the normal use of synthesizer body has been guaranteed. Through the linkage control system of the indoor temperature and the humidity in the DNA synthesizer, the step of manually adjusting the ambient temperature of the position of the synthesizer body according to the experience and the humidity in the synthesizer body is omitted, the automation degree and the self-adaptive capacity of the synthesizer body are improved, and the influence of manual operation on the normal work of the synthesizer body is further reduced.
Further, the control device includes:
the first controller is arranged in the room and is in communication connection with the temperature adjusting device;
and the second controller is arranged on the synthesizer body and is in communication connection with the humidity adjusting device.
Further, the humidity adjusting apparatus includes:
the gas storage tank stores inert gas and is connected to the synthesizer body through a pipeline;
and the adjusting assembly is connected to the pipeline and is in communication connection with the second controller.
Further, the adjustment assembly includes:
the switching valve is connected to the pipeline and is in communication connection with the second controller so as to control the opening and closing of the switching valve through the second controller;
and the speed regulating valve is connected to the pipeline and is positioned between the switch valve and the synthesizer body.
Further, the humidity adjusting apparatus includes:
the gas storage tank stores inert gas and is connected to the synthesizer body through a pipeline;
the adjusting assembly is connected to the pipeline, and the adjusting assembly and the temperature adjusting device are in communication connection with the control device.
Further, the adjustment assembly includes:
the switching valve is connected to the pipeline and is in communication connection with the control device so as to control the switching of the switching valve through the control device;
and the speed regulating valve is connected to the pipeline and is positioned between the switch valve and the synthesizer body.
Further, the switch valve is a two-position two-way electromagnetic valve, the air outlet end of the two-position two-way electromagnetic valve is communicated with the air inlet end of the speed regulating valve through the pipeline, and the air inlet end of the two-position two-way electromagnetic valve is communicated with the air storage tank through the pipeline.
The invention also provides a linkage control method of the linkage control system of the indoor temperature and the humidity in the DNA synthesizer, which comprises the following steps:
acquiring the ambient temperature and/or the ambient humidity;
judging the size relation between the environment temperature and an environment temperature threshold value, and/or judging the size relation between the environment humidity and an environment humidity threshold value;
and controlling the temperature adjusting device and/or the humidity adjusting device according to the judgment result.
According to the linkage control method for the indoor temperature and the humidity in the DNA synthesizer, provided by the embodiment of the invention, the humidity in the synthesizer body and the environmental temperature of the position where the synthesizer body is located are obtained, and the detected humidity and temperature are converted into a humidity signal and a temperature signal and are sent to the control device. After controlling means received humidity signal and temperature signal, can compare humidity signal and temperature signal and the humidity threshold value and the temperature threshold value of prestoring in controlling means, and control indoor temperature regulation apparatus according to the comparison result, perhaps control the humidity regulation apparatus in the synthesizer body, thereby realized accurate closed-loop control to the humidity of this internal and the ambient temperature of synthesizer body position, and then can make this internal humidity of synthesizer and the ambient temperature of synthesizer body position all maintain reasonable within range, the normal use of synthesizer body has been guaranteed. The error caused by manual adjustment is eliminated, and the automation degree and the self-adaptive capacity of the synthesizer body are improved.
Further, the humidity adjusting device comprises an adjusting component;
the step of controlling the humidity control device and/or the humidity control device according to the judgment result further includes:
if the environmental humidity is greater than the environmental humidity threshold value, controlling the adjusting assembly to introduce inert gas into the synthesizer body;
if the environment humidity is smaller than the environment humidity threshold value, the adjusting component is controlled to be closed, and/or the temperature adjusting device is controlled to be cooled.
The invention also provides an electronic device, which comprises a memory, a processor and a computer program which is stored on the memory and can run on the processor, wherein the processor executes the program to realize the steps of the linkage control method of the indoor temperature and the humidity in the DNA synthesizer.
One or more technical solutions in the embodiments of the present invention have at least one of the following technical effects:
according to the linkage control system for the indoor temperature and the humidity in the DNA synthesizer, provided by the embodiment of the invention, the detection piece is arranged, so that the humidity in the synthesizer body and the environmental temperature of the position where the synthesizer body is located can be accurately detected, the detected humidity and temperature are converted into a humidity signal and a temperature signal, and the humidity signal and the temperature signal are sent to the control device. After controlling means received humidity signal and temperature signal, can compare humidity signal and temperature signal and the humidity threshold value and the temperature threshold value of prestoring in controlling means, and control indoor temperature regulation apparatus according to the comparison result, perhaps control the humidity regulation apparatus in the synthesizer body, thereby realized accurate closed-loop control to the humidity of this internal and the ambient temperature of synthesizer body position, and then can make this internal humidity of synthesizer and the ambient temperature of synthesizer body position all maintain reasonable within range, the normal use of synthesizer body has been guaranteed. Through the linkage control system of the indoor temperature and the humidity in the synthesizer body, the step of manually adjusting the ambient temperature of the position of the synthesizer body according to the experience corresponding to the humidity in the synthesizer body is omitted, the automation degree and the self-adaptive capacity of the synthesizer body are improved, and the influence of manual operation on the normal work of the synthesizer body is further reduced.
According to the linkage control method for the indoor temperature and the humidity in the DNA synthesizer, provided by the embodiment of the invention, the humidity in the synthesizer body and the environmental temperature of the position where the synthesizer body is located are obtained, and the detected humidity and temperature are converted into a humidity signal and a temperature signal and are sent to the control device. After controlling means received humidity signal and temperature signal, can compare humidity signal and temperature signal and the humidity threshold value and the temperature threshold value of prestoring in controlling means, and control indoor temperature regulation apparatus according to the comparison result, perhaps control the humidity regulation apparatus in the synthesizer body, thereby realized accurate closed-loop control to the humidity of this internal and the ambient temperature of synthesizer body position, and then can make this internal humidity of synthesizer and the ambient temperature of synthesizer body position all maintain reasonable within range, the normal use of synthesizer body has been guaranteed. The error caused by manual adjustment is eliminated, and the automation degree and the self-adaptive capacity of the synthesizer body are improved.
Drawings
FIG. 1 is a schematic structural diagram of a linkage control system for indoor temperature and humidity in a DNA synthesizer according to an embodiment of the present invention;
FIG. 2 is a schematic flow chart of a method for controlling the indoor temperature and the humidity in the DNA synthesizer in a linkage manner according to an embodiment of the present invention;
FIG. 3 is a schematic block diagram of an electronic device provided by an embodiment of the invention; .
The reference numbers illustrate:
100. a detection member; 102. a synthesizer body; 104. a temperature adjustment device; 106. a first controller; 108. a second controller; 110. a gas storage tank; 112. a pipeline; 114. an on-off valve; 116. a speed regulating valve; 118. a processor; 120. a communication interface; 122. a memory; 124. a communication bus; 126. a synthesis chamber.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be described below with reference to the accompanying drawings, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the embodiments of the present invention, it should be noted that the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience in describing the embodiments of the present invention and simplifying the description, but do not indicate or imply that the referred devices or elements must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the embodiments of the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the embodiments of the present invention, it should be noted that, unless explicitly stated or limited otherwise, the terms "connected" and "connected" are to be interpreted broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; may be directly connected or indirectly connected through an intermediate. Specific meanings of the above terms in the embodiments of the present invention can be understood in specific cases by those of ordinary skill in the art.
In embodiments of the invention, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through intervening media. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of an embodiment of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.
As shown in FIG. 1, the present invention provides a linkage control system for indoor temperature and humidity in a DNA synthesizer, comprising a detection unit 100, a temperature adjustment device 104, a humidity adjustment device and a control device; the detection piece 100 is disposed in the synthesizer body 102 and is used for detecting an ambient temperature and an ambient humidity in the synthesizer body 102; the temperature adjustment device 104 is disposed indoors; the humidity adjusting device is arranged in the synthesizer body 102, and the synthesizer body 102 is arranged indoors; the control device controls the temperature adjustment device 104 and/or the humidity adjustment device based on the detection signal of the detection member 100.
According to the linkage control system for the indoor temperature and the humidity in the DNA synthesizer, provided by the embodiment of the invention, the detection piece 100 is arranged, so that the humidity in the synthesizer body 102 and the environmental temperature of the position where the synthesizer body 102 is located can be accurately detected, the detected humidity and temperature are converted into a humidity signal and a temperature signal, and the humidity signal and the temperature signal are sent to the control device. After the control device receives the humidity signal and the temperature signal, the humidity signal and the temperature signal can be compared with a humidity threshold and a temperature threshold which are stored in the control device in advance, the indoor temperature adjusting device 104 is controlled according to a comparison result, or the humidity adjusting device in the synthesizer body 102 is controlled, so that accurate closed-loop control is realized on the humidity in the synthesizer body 102 and the environment temperature of the position where the synthesizer body 102 is located, the humidity in the synthesizer body 102 and the environment temperature of the position where the synthesizer body 102 is located can be maintained within a reasonable range, and normal use of the synthesizer body 102 is guaranteed. Through the linkage control system of the indoor temperature and the humidity in the DNA synthesizer, the step of manually adjusting the ambient temperature of the position of the synthesizer body 102 correspondingly according to the humidity in the synthesizer body 102 and experience is omitted, the automation degree and the self-adaptive capacity of the synthesizer body 102 are improved, and the influence of manual operation on the normal work of the synthesizer body 102 is further reduced.
Specifically, in the system for controlling the indoor temperature and the humidity inside the DNA synthesizer in a linkage manner provided by the embodiment of the present invention, the detection member 100 is used for detecting the ambient temperature and the ambient humidity inside the synthesizer body 102, so that in the embodiment of the present invention, the detection member 100 is disposed inside the synthesizer body 102, for example, the detection member 100 may be disposed inside the synthesis chamber 126 in the synthesizer body 102. For example, a temperature and humidity sensor may be used as the detecting member 100, and other sensor devices equipped with humidity-sensitive and heat-sensitive elements and capable of measuring temperature and humidity may be used.
The temperature control device 104 is installed indoors, and the synthesizer main body 102 is also installed indoors. For example, the room may be a laboratory room, and the temperature control device 104 may be a central air conditioner, a cabinet, an on-hook device, or the like that can control the temperature in the laboratory room.
The humidity control device is disposed on the synthesizer body 102 and is used to control the humidity inside the synthesizer body 102.
The control device is in communication connection with the temperature adjusting device 104, the humidity adjusting device and the detecting element 100, so that after the detecting element 100 detects the indoor temperature and the humidity in the synthesizer body 102, the corresponding temperature signal and humidity signal are sent to the control device, and the control device can automatically judge whether the indoor temperature and the humidity in the synthesizer body 102 are in the optimal range based on the corresponding detection signal. If the indoor temperature and the humidity in the synthesizer body 102 do not meet the actual standard, the control device generates a corresponding control signal to control the temperature adjustment device 104 to adjust the indoor temperature, or generates a corresponding control signal to control the humidity adjustment device to adjust the humidity in the synthesizer body 102, or simultaneously controls the temperature adjustment device 104 and the humidity adjustment device.
In the embodiment of the present invention, the control device may include two realizable manners. The specific control of the control device is explained further below in terms of two realizable ways.
The implementation mode is as follows:
in this implementable manner, the control means includes a first controller 106 and a second controller 108; the first controller 106 is disposed indoors and is in communication connection with the temperature adjustment device 104; the second controller 108 is disposed on the synthesizer body 102 and is in communication with the humidity control device.
As shown in fig. 1, the first controller 106 is disposed indoors for controlling the thermostat 104, and the detecting member 100 is also communicatively connected to the first controller 106 for precise closed-loop control. The second controller 108 is disposed on the synthesizer body 102 for controlling the humidity control device, and the detecting member 100 is also communicatively connected to the second controller 108 for precise closed-loop control. In other words, in this implementable manner, the thermostat 104 and the humidifier are controlled by the first controller 106 and the second controller 108, respectively.
That is, after the temperature in the laboratory rises, the first controller 106 controls the temperature adjustment device 104 to introduce cool air into the laboratory to reduce the temperature in the laboratory; when the temperature in the laboratory is lowered, the first controller 106 controls the temperature adjustment device 104 to introduce hot air into the laboratory to increase the temperature in the laboratory. By controlling the temperature adjustment device 104, the synthesizer body 102 can be always in a reasonable temperature environment.
In this realisable form, the humidity conditioning means comprises a gas reservoir 110 and a conditioning assembly; wherein, the gas storage tank 110 stores inert gas and is connected to the synthesizer body 102 through a pipeline 112; the regulating assembly is connected to the pipeline 112 and is in communication connection with the second controller 108; the regulating assembly comprises a switch valve 114 and a speed regulating valve 116; wherein, the switch valve 114 is connected to the pipeline 112 and is connected to the second controller 108 in communication so as to control the opening and closing thereof by the second controller 108; the speed valve 116 is connected to the line 112 and is located between the on-off valve 114 and the synthesizer body 102.
Referring to fig. 1, the gas tank 110 is used for storing inert gas, such as helium, argon, etc., and the gas tank 110 is communicated with the synthesis chamber 126 through a pipeline 112 to achieve the purpose of introducing the inert gas into the synthesis chamber 126.
A regulating assembly is also arranged on the pipeline 112, wherein, from the gas storage tank 110 to the direction of the synthesizer body 102, a switch valve 114 and a speed regulating valve 116 are arranged on the pipeline 112 in sequence, wherein the switch valve 114 is in communication connection with the second controller 108. When the second controller 108 controls the switch valve 114 to open the pipeline 112, which means that the gas storage tank 110 is communicated with the synthesis chamber 126, the inert gas in the gas storage tank 110 can flow into the synthesis chamber 126 at a certain flow rate through the speed regulation of the speed regulation valve 116. When the second controller 108 controls the on-off valve 114 to close the pipeline 112, it is equivalent to the air storage tank 110 not being communicated with the synthesis chamber 126. It should be noted that when the inert gas is introduced into the synthesis chamber 126, the humidity in the synthesis chamber 126 is reduced; after the inert gas is stopped from being introduced into the synthesis chamber 126, the humidity in the synthesis chamber 126 gradually increases with the operation of the synthesizer body 102.
The second implementation mode:
in this realisable form, the humidity conditioning means comprises a gas reservoir 110 and a conditioning assembly; wherein, the gas storage tank 110 stores inert gas and is connected to the synthesizer body 102 through a pipeline 112; the adjusting assembly is connected to the pipeline 112, and the adjusting assembly and the temperature adjusting device 104 are in communication connection with the control device; the regulating assembly comprises a switch valve 114 and a speed regulating valve 116; wherein, the switch valve 114 is connected to the pipeline 112 and is in communication connection with the control device to control the opening and closing thereof through the control device; the speed valve 116 is connected to the line 112 and is located between the on-off valve 114 and the synthesizer body 102.
The main difference between the first and second realizations is the difference in the control device, in which the control device simultaneously realizes the control of the temperature adjustment device 104 and the humidity adjustment device. The rest of the contents are the same as the first realizable manner, and are not described again here.
Further, in both implementations, the on-off valve 114 is a two-position two-way solenoid valve. That is, the air outlet end of the two-position two-way electromagnetic valve is communicated with the air inlet end of the speed regulating valve 116 through the pipeline 112, and the air inlet end of the two-position two-way electromagnetic valve is communicated with the air storage tank 110 through the pipeline 112. When the humidity value detected by the detection part 100 is higher than the upper limit value, a humidity signal is fed back to the control device, the control device controls the two-position two-way electromagnetic valve to open, inert gas is ensured to be introduced into the synthesis chamber 126 at a certain flow rate through the speed regulating valve 116, when the humidity value is reduced to a target value, the control device controls the two-position two-way electromagnetic valve to close, inflation is stopped, and the steps are repeated, so that the humidity control of the synthesis chamber 126 is completed, and the humidity is always controlled within a certain range.
As shown in fig. 2, the present invention further provides a linkage control method of the linkage control system for indoor temperature and humidity in a DNA synthesizer, comprising:
s100, acquiring the ambient temperature and/or the ambient humidity;
s200, judging the size relation between the environment temperature and the environment temperature threshold value, and/or judging the size relation between the environment humidity and the environment humidity threshold value;
and S300, controlling the temperature adjusting device 104 and/or the humidity adjusting device according to the judgment result.
According to the linkage control method for the indoor temperature and the humidity in the DNA synthesizer, provided by the embodiment of the invention, the humidity in the synthesizer body 102 and the environmental temperature of the position where the synthesizer body 102 is located are obtained, and the detected humidity and temperature are converted into a humidity signal and a temperature signal and are sent to the control device. After the control device receives the humidity signal and the temperature signal, the humidity signal and the temperature signal can be compared with a humidity threshold and a temperature threshold which are stored in the control device in advance, the indoor temperature adjusting device 104 is controlled according to a comparison result, or the humidity adjusting device in the synthesizer body 102 is controlled, so that accurate closed-loop control is realized on the humidity in the synthesizer body 102 and the environment temperature of the position where the synthesizer body 102 is located, the humidity in the synthesizer body 102 and the environment temperature of the position where the synthesizer body 102 is located can be maintained within a reasonable range, and normal use of the synthesizer body 102 is guaranteed. The error caused by manual adjustment is eliminated, and the automation degree and the self-adaptive capacity of the synthesizer body 102 are improved.
Specifically, in step S100, the ambient temperature of the laboratory and/or the humidity in the synthesis chamber 126 are/is acquired by the detection member 100, and a temperature signal and/or a humidity signal are/is generated, and then the temperature signal and/or the humidity signal are/is sent to the control device;
in step S200, after acquiring the temperature signal and/or the humidity signal, the control device compares the temperature signal and/or the humidity signal with a temperature threshold and/or a humidity threshold pre-stored in the control device, and determines a detected temperature value and a detected temperature threshold, and/or a detected humidity value and a detected humidity threshold.
In step S300, if the detected temperature value is not equal to the temperature threshold, or the detected temperature value is not within the range of the pre-stored temperature threshold, the control device controls the temperature adjustment device 104 to adjust the temperature in the laboratory; if the detected humidity value is not equal to the humidity threshold value, or the detected humidity value is not within the range of the pre-stored humidity threshold value, the control device controls the humidity adjusting device to adjust the humidity in the synthesizer body 102.
Further, in step S300, the method further includes:
s400, if the environmental humidity is larger than the environmental humidity threshold value, controlling the adjusting assembly to introduce inert gas into the synthesizer body 102;
as previously described, if the humidity within the synthesis chamber 126 exceeds a humidity threshold or humidity threshold range, inert gas is introduced into the synthesis chamber 126 to reduce the humidity within the synthesis chamber 126;
if the ambient humidity is less than the ambient humidity threshold, the regulating component is controlled to be turned off, and/or the temperature regulating device 104 is controlled to be cooled.
As mentioned above, if the humidity in the synthesis chamber 126 is less than the humidity threshold or the humidity threshold range, the inert gas is stopped from being introduced into the synthesis chamber 126, and/or the temperature adjustment device 104 is controlled to reduce the temperature in the laboratory, so as to increase the humidity in the synthesis chamber 126.
As shown in fig. 3, the present invention further provides an electronic device, which includes a memory 122, a processor 118 and a computer program stored in the memory 122 and executable on the processor 118, wherein the processor 118 executes the computer program to implement the steps of the method for controlling the linkage between the indoor temperature and the humidity in the DNA synthesizer.
Fig. 3 illustrates a physical structure diagram of an electronic device, which may include, as shown in fig. 3: a processor 118, a communication interface 120, a memory 122 and a communication bus 124, wherein the processor 118, the communication interface 120 and the memory 122 are communicated with each other through the communication bus 124. The processor 118 may invoke logic instructions in the memory 122 to perform the method of coordinated control of indoor temperature and humidity within the DNA synthesizer as described above, the method comprising:
s100, acquiring the ambient temperature and/or the ambient humidity;
s200, judging the size relation between the environment temperature and the environment temperature threshold value, and/or judging the size relation between the environment humidity and the environment humidity threshold value;
s300, controlling a temperature adjusting device and/or a humidity adjusting device according to the judgment result;
s400, if the environmental humidity is larger than an environmental humidity threshold value, controlling the adjusting assembly to introduce inert gas into the synthesizer body; and if the ambient humidity is less than the ambient humidity threshold value, controlling the adjusting assembly to be closed, and/or controlling the temperature adjusting device to cool down.
Furthermore, the logic instructions in the memory 122 may be implemented in software functional units and stored in a computer readable storage medium when sold or used as a stand-alone product. Based on such understanding, the technical solution of the present invention may be embodied in the form of a software product, which is stored in a storage medium and includes instructions for causing a computer device (which may be a personal computer, a server, or a network device) to execute all or part of the steps of the method according to the embodiments of the present invention. And the aforementioned storage medium includes: a U-disk, a removable hard disk, a Read-Only Memory (ROM), a Random Access Memory (RAM), a magnetic disk or an optical disk, and other various media capable of storing program codes.
In summary, one or more of the technical solutions in the embodiments of the present invention at least have one of the following technical effects:
according to the linkage control system for the indoor temperature and the humidity in the DNA synthesizer, provided by the embodiment of the invention, the detection piece 100 is arranged, so that the humidity in the synthesizer body 102 and the environmental temperature of the position where the synthesizer body 102 is located can be accurately detected, the detected humidity and temperature are converted into a humidity signal and a temperature signal, and the humidity signal and the temperature signal are sent to the control device. After the control device receives the humidity signal and the temperature signal, the humidity signal and the temperature signal can be compared with a humidity threshold and a temperature threshold which are stored in the control device in advance, the indoor temperature adjusting device 104 is controlled according to a comparison result, or the humidity adjusting device in the synthesizer body 102 is controlled, so that accurate closed-loop control is realized on the humidity in the synthesizer body 102 and the environment temperature of the position where the synthesizer body 102 is located, the humidity in the synthesizer body 102 and the environment temperature of the position where the synthesizer body 102 is located can be maintained within a reasonable range, and normal use of the synthesizer body 102 is guaranteed. Through the linkage control system of the indoor temperature and the humidity in the synthesizer body 102, the step of manually adjusting the ambient temperature of the position of the synthesizer body 102 correspondingly according to the humidity in the synthesizer body 102 and experience is omitted, the automation degree and the self-adaptive capacity of the synthesizer body 102 are improved, and the influence of manual operation on the normal work of the synthesizer body 102 is further reduced.
According to the linkage control method for the indoor temperature and the humidity in the DNA synthesizer, provided by the embodiment of the invention, the humidity in the synthesizer body 102 and the environmental temperature of the position where the synthesizer body 102 is located are obtained, and the detected humidity and temperature are converted into a humidity signal and a temperature signal and are sent to the control device. After the control device receives the humidity signal and the temperature signal, the humidity signal and the temperature signal can be compared with a humidity threshold and a temperature threshold which are stored in the control device in advance, the indoor temperature adjusting device 104 is controlled according to a comparison result, or the humidity adjusting device in the synthesizer body 102 is controlled, so that accurate closed-loop control is realized on the humidity in the synthesizer body 102 and the environment temperature of the position where the synthesizer body 102 is located, the humidity in the synthesizer body 102 and the environment temperature of the position where the synthesizer body 102 is located can be maintained within a reasonable range, and normal use of the synthesizer body 102 is guaranteed. The error caused by manual adjustment is eliminated, and the automation degree and the self-adaptive capacity of the synthesizer body 102 are improved.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (10)

1. A linkage control system of indoor temperature and humidity in a DNA synthesizer is characterized by comprising:
the detection piece (100) is arranged in the synthesizer body (102) and is used for detecting the ambient temperature and the ambient humidity in the synthesizer body (102);
a temperature control device (104) installed indoors;
the humidity adjusting device is arranged in the synthesizer body (102), and the synthesizer body (102) is arranged in the chamber;
a control device that controls the temperature adjustment device (104) and/or the humidity adjustment device based on a detection signal of the detection member (100).
2. The system for controlling the indoor temperature and the humidity inside the DNA synthesizer according to claim 1, wherein the control device comprises:
a first controller (106) disposed within the chamber and communicatively coupled to the thermostat (104);
and the second controller (108) is arranged on the synthesizer body (102) and is in communication connection with the humidity adjusting device.
3. The system for controlling the indoor temperature and the humidity in the DNA synthesizer in a linked manner according to claim 2, wherein the humidity control device comprises:
a gas storage tank (110) which stores inert gas and is connected to the synthesizer body (102) through a pipeline (112);
a conditioning assembly coupled to the conduit (112) and communicatively coupled to the second controller (108).
4. The system of claim 3, wherein the adjusting assembly comprises:
a switching valve (114) connected to the pipeline (112) and in communication with the second controller (108) to be controlled to open and close by the second controller (108);
and the speed regulating valve (116) is connected to the pipeline (112) and is positioned between the switch valve (114) and the synthesizer body (102).
5. The system for controlling the indoor temperature and the humidity in the DNA synthesizer according to claim 1, wherein the humidity control device comprises:
a gas storage tank (110) which stores inert gas and is connected to the synthesizer body (102) through a pipeline (112);
a regulating assembly connected to the conduit (112), the regulating assembly and the temperature regulating device (104) each being in communicative connection with the control device.
6. The system of claim 5, wherein the adjusting assembly comprises:
a switching valve (114) connected to the pipeline (112) and in communication with the control device to control the opening and closing thereof by the control device;
and the speed regulating valve (116) is connected to the pipeline (112) and is positioned between the switch valve (114) and the synthesizer body (102).
7. The linkage control system for indoor temperature and humidity in DNA synthesizer according to claim 4 or 6, wherein the switch valve (114) is a two-position two-way solenoid valve, the air outlet end of the two-position two-way solenoid valve is communicated with the air inlet end of the speed regulating valve (116) through the pipeline (112), and the air inlet end of the two-position two-way solenoid valve is communicated with the air storage tank (110) through the pipeline (112).
8. A linkage control method of a linkage control system of indoor temperature and humidity in a DNA synthesizer according to any one of claims 1 to 7, comprising:
acquiring the ambient temperature and/or the ambient humidity;
judging the size relation between the environment temperature and an environment temperature threshold value, and/or judging the size relation between the environment humidity and an environment humidity threshold value;
and controlling the temperature adjusting device (104) and/or the humidity adjusting device according to the judgment result.
9. The method according to claim 8, wherein the humidity control device comprises a regulating component;
the step of controlling the humidity control device and/or the humidity control device according to the judgment result further includes:
if the environmental humidity is larger than the environmental humidity threshold value, controlling the adjusting assembly to introduce inert gas into the synthesizer body (102);
if the ambient humidity is less than the ambient humidity threshold value, the adjusting component is controlled to be closed, and/or the temperature adjusting device (104) is controlled to be cooled.
10. An electronic device comprising a memory (122), a processor (118) and a computer program stored on the memory (122) and executable on the processor (118), wherein the processor (118) when executing the program implements the steps of the method for linked control of indoor temperature and humidity in a DNA synthesizer according to claim 8 or 9.
CN202010746954.2A 2020-07-29 2020-07-29 Linkage control system and method for indoor temperature and humidity in DNA synthesizer Active CN111949058B (en)

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